Amino acid dipepetide frequency for Wuchang romanomermis nematode virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.57AlaAla: 6.57 ± 2.276
0.986AlaCys: 0.986 ± 0.492
3.942AlaAsp: 3.942 ± 2.367
3.614AlaGlu: 3.614 ± 0.454
3.614AlaPhe: 3.614 ± 1.026
2.628AlaGly: 2.628 ± 0.562
1.971AlaHis: 1.971 ± 0.977
7.884AlaIle: 7.884 ± 1.962
1.971AlaLys: 1.971 ± 0.402
6.242AlaLeu: 6.242 ± 1.402
1.971AlaMet: 1.971 ± 0.527
1.971AlaAsn: 1.971 ± 1.722
1.971AlaPro: 1.971 ± 0.56
1.971AlaGln: 1.971 ± 0.798
2.957AlaArg: 2.957 ± 0.94
5.256AlaSer: 5.256 ± 1.498
2.628AlaThr: 2.628 ± 0.413
3.614AlaVal: 3.614 ± 0.459
0.986AlaTrp: 0.986 ± 0.462
2.957AlaTyr: 2.957 ± 0.767
0.0AlaXaa: 0.0 ± 0.0
Cys
0.329CysAla: 0.329 ± 0.164
0.0CysCys: 0.0 ± 0.0
0.657CysAsp: 0.657 ± 0.328
2.3CysGlu: 2.3 ± 1.291
0.657CysPhe: 0.657 ± 0.328
0.657CysGly: 0.657 ± 0.328
0.329CysHis: 0.329 ± 0.164
0.329CysIle: 0.329 ± 0.164
1.314CysLys: 1.314 ± 1.016
1.971CysLeu: 1.971 ± 0.984
0.329CysMet: 0.329 ± 0.537
0.0CysAsn: 0.0 ± 0.0
0.329CysPro: 0.329 ± 0.164
0.329CysGln: 0.329 ± 0.164
1.643CysArg: 1.643 ± 0.423
1.314CysSer: 1.314 ± 0.73
0.329CysThr: 0.329 ± 0.164
1.643CysVal: 1.643 ± 0.82
0.0CysTrp: 0.0 ± 0.0
1.643CysTyr: 1.643 ± 0.82
0.0CysXaa: 0.0 ± 0.0
Asp
2.3AspAla: 2.3 ± 0.776
0.329AspCys: 0.329 ± 0.164
2.3AspAsp: 2.3 ± 1.148
1.971AspGlu: 1.971 ± 0.725
0.986AspPhe: 0.986 ± 0.462
1.643AspGly: 1.643 ± 0.547
0.986AspHis: 0.986 ± 0.492
5.913AspIle: 5.913 ± 1.861
4.599AspLys: 4.599 ± 0.659
6.242AspLeu: 6.242 ± 1.045
1.971AspMet: 1.971 ± 1.34
0.657AspAsn: 0.657 ± 0.66
3.285AspPro: 3.285 ± 0.374
1.314AspGln: 1.314 ± 0.5
2.3AspArg: 2.3 ± 0.845
4.599AspSer: 4.599 ± 1.704
1.643AspThr: 1.643 ± 0.431
5.585AspVal: 5.585 ± 1.512
0.657AspTrp: 0.657 ± 0.328
2.3AspTyr: 2.3 ± 0.445
0.0AspXaa: 0.0 ± 0.0
Glu
1.314GluAla: 1.314 ± 0.499
1.314GluCys: 1.314 ± 0.655
2.957GluAsp: 2.957 ± 1.156
4.271GluGlu: 4.271 ± 0.496
3.614GluPhe: 3.614 ± 1.437
2.628GluGly: 2.628 ± 0.413
1.314GluHis: 1.314 ± 0.656
5.913GluIle: 5.913 ± 1.87
8.541GluLys: 8.541 ± 1.631
5.585GluLeu: 5.585 ± 0.884
1.971GluMet: 1.971 ± 0.977
2.3GluAsn: 2.3 ± 0.981
1.314GluPro: 1.314 ± 0.5
1.643GluGln: 1.643 ± 1.0
1.971GluArg: 1.971 ± 0.71
3.285GluSer: 3.285 ± 0.794
3.942GluThr: 3.942 ± 0.981
2.3GluVal: 2.3 ± 0.704
0.657GluTrp: 0.657 ± 0.328
1.643GluTyr: 1.643 ± 1.24
0.0GluXaa: 0.0 ± 0.0
Phe
2.957PheAla: 2.957 ± 0.903
0.986PheCys: 0.986 ± 0.824
2.3PheAsp: 2.3 ± 0.842
3.285PheGlu: 3.285 ± 1.168
2.957PhePhe: 2.957 ± 0.753
1.971PheGly: 1.971 ± 0.604
1.971PheHis: 1.971 ± 0.984
1.971PheIle: 1.971 ± 0.644
1.314PheLys: 1.314 ± 0.655
2.957PheLeu: 2.957 ± 0.907
1.314PheMet: 1.314 ± 1.055
2.3PheAsn: 2.3 ± 0.616
3.942PhePro: 3.942 ± 1.487
1.971PheGln: 1.971 ± 0.71
1.643PheArg: 1.643 ± 0.787
3.942PheSer: 3.942 ± 1.301
1.971PheThr: 1.971 ± 0.924
2.3PheVal: 2.3 ± 0.842
0.986PheTrp: 0.986 ± 0.492
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.971GlyAla: 1.971 ± 0.645
1.643GlyCys: 1.643 ± 0.665
1.314GlyAsp: 1.314 ± 0.656
1.971GlyGlu: 1.971 ± 0.993
2.628GlyPhe: 2.628 ± 0.795
2.957GlyGly: 2.957 ± 1.01
1.643GlyHis: 1.643 ± 0.665
2.628GlyIle: 2.628 ± 0.537
2.957GlyLys: 2.957 ± 1.074
4.271GlyLeu: 4.271 ± 0.871
0.329GlyMet: 0.329 ± 0.538
1.971GlyAsn: 1.971 ± 0.491
1.314GlyPro: 1.314 ± 0.947
1.971GlyGln: 1.971 ± 0.977
1.971GlyArg: 1.971 ± 0.71
1.971GlySer: 1.971 ± 0.644
2.3GlyThr: 2.3 ± 0.697
2.628GlyVal: 2.628 ± 0.932
0.986GlyTrp: 0.986 ± 0.492
0.986GlyTyr: 0.986 ± 0.492
0.0GlyXaa: 0.0 ± 0.0
His
1.643HisAla: 1.643 ± 1.397
0.0HisCys: 0.0 ± 0.0
0.329HisAsp: 0.329 ± 0.164
0.986HisGlu: 0.986 ± 0.492
0.986HisPhe: 0.986 ± 0.492
0.657HisGly: 0.657 ± 0.328
1.314HisHis: 1.314 ± 0.507
2.957HisIle: 2.957 ± 1.131
1.314HisLys: 1.314 ± 0.656
2.628HisLeu: 2.628 ± 0.537
0.986HisMet: 0.986 ± 0.76
0.986HisAsn: 0.986 ± 0.999
2.628HisPro: 2.628 ± 1.254
0.0HisGln: 0.0 ± 0.0
0.329HisArg: 0.329 ± 0.164
0.986HisSer: 0.986 ± 0.612
1.314HisThr: 1.314 ± 0.656
0.986HisVal: 0.986 ± 0.492
0.657HisTrp: 0.657 ± 0.328
0.986HisTyr: 0.986 ± 0.492
0.0HisXaa: 0.0 ± 0.0
Ile
6.57IleAla: 6.57 ± 0.513
3.285IleCys: 3.285 ± 0.651
4.599IleAsp: 4.599 ± 3.752
4.599IleGlu: 4.599 ± 1.91
3.285IlePhe: 3.285 ± 1.304
2.628IleGly: 2.628 ± 0.695
1.314IleHis: 1.314 ± 0.655
5.585IleIle: 5.585 ± 2.191
4.271IleLys: 4.271 ± 0.919
9.198IleLeu: 9.198 ± 1.625
2.3IleMet: 2.3 ± 1.208
4.271IleAsn: 4.271 ± 0.796
3.614IlePro: 3.614 ± 0.961
3.942IleGln: 3.942 ± 1.097
1.971IleArg: 1.971 ± 1.137
4.599IleSer: 4.599 ± 1.4
5.585IleThr: 5.585 ± 1.983
2.957IleVal: 2.957 ± 0.666
0.657IleTrp: 0.657 ± 0.328
4.599IleTyr: 4.599 ± 1.407
0.0IleXaa: 0.0 ± 0.0
Lys
6.57LysAla: 6.57 ± 1.411
0.0LysCys: 0.0 ± 0.0
1.971LysAsp: 1.971 ± 0.664
3.285LysGlu: 3.285 ± 0.881
2.3LysPhe: 2.3 ± 0.616
2.3LysGly: 2.3 ± 0.776
0.657LysHis: 0.657 ± 0.354
6.57LysIle: 6.57 ± 0.703
2.628LysLys: 2.628 ± 1.0
5.913LysLeu: 5.913 ± 1.827
1.971LysMet: 1.971 ± 0.637
3.285LysAsn: 3.285 ± 1.387
0.986LysPro: 0.986 ± 1.115
2.3LysGln: 2.3 ± 2.149
2.957LysArg: 2.957 ± 0.622
4.599LysSer: 4.599 ± 0.948
3.942LysThr: 3.942 ± 1.12
2.628LysVal: 2.628 ± 0.652
0.986LysTrp: 0.986 ± 0.492
3.614LysTyr: 3.614 ± 0.714
0.0LysXaa: 0.0 ± 0.0
Leu
6.242LeuAla: 6.242 ± 0.833
1.314LeuCys: 1.314 ± 0.656
5.913LeuAsp: 5.913 ± 1.455
7.227LeuGlu: 7.227 ± 1.297
5.585LeuPhe: 5.585 ± 1.515
2.628LeuGly: 2.628 ± 1.03
0.657LeuHis: 0.657 ± 0.328
8.213LeuIle: 8.213 ± 2.108
5.256LeuLys: 5.256 ± 0.926
13.141LeuLeu: 13.141 ± 4.512
1.314LeuMet: 1.314 ± 0.718
6.242LeuAsn: 6.242 ± 1.246
5.585LeuPro: 5.585 ± 1.475
5.585LeuGln: 5.585 ± 1.865
5.913LeuArg: 5.913 ± 1.43
9.855LeuSer: 9.855 ± 1.721
7.556LeuThr: 7.556 ± 1.356
4.271LeuVal: 4.271 ± 0.86
0.657LeuTrp: 0.657 ± 0.937
2.628LeuTyr: 2.628 ± 0.701
0.0LeuXaa: 0.0 ± 0.0
Met
1.314MetAla: 1.314 ± 1.355
0.329MetCys: 0.329 ± 0.164
0.657MetAsp: 0.657 ± 0.473
0.657MetGlu: 0.657 ± 0.992
0.329MetPhe: 0.329 ± 0.164
0.986MetGly: 0.986 ± 0.612
0.329MetHis: 0.329 ± 0.164
1.971MetIle: 1.971 ± 0.604
2.957MetLys: 2.957 ± 2.026
3.285MetLeu: 3.285 ± 0.843
0.657MetMet: 0.657 ± 0.328
1.643MetAsn: 1.643 ± 1.324
1.643MetPro: 1.643 ± 1.182
1.643MetGln: 1.643 ± 0.82
0.986MetArg: 0.986 ± 0.496
2.628MetSer: 2.628 ± 1.473
2.3MetThr: 2.3 ± 1.144
3.614MetVal: 3.614 ± 1.068
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.928AsnAla: 4.928 ± 0.807
0.329AsnCys: 0.329 ± 0.164
2.3AsnAsp: 2.3 ± 0.842
2.957AsnGlu: 2.957 ± 0.892
1.971AsnPhe: 1.971 ± 0.71
2.3AsnGly: 2.3 ± 2.41
0.986AsnHis: 0.986 ± 0.492
2.628AsnIle: 2.628 ± 0.825
2.957AsnLys: 2.957 ± 0.858
7.227AsnLeu: 7.227 ± 3.073
0.986AsnMet: 0.986 ± 0.492
1.643AsnAsn: 1.643 ± 0.787
2.3AsnPro: 2.3 ± 1.139
1.314AsnGln: 1.314 ± 1.092
2.3AsnArg: 2.3 ± 0.445
1.314AsnSer: 1.314 ± 0.656
2.628AsnThr: 2.628 ± 1.361
0.986AsnVal: 0.986 ± 0.462
0.329AsnTrp: 0.329 ± 0.164
2.957AsnTyr: 2.957 ± 0.646
0.0AsnXaa: 0.0 ± 0.0
Pro
2.628ProAla: 2.628 ± 1.741
1.643ProCys: 1.643 ± 0.595
3.614ProAsp: 3.614 ± 0.961
2.628ProGlu: 2.628 ± 0.668
2.628ProPhe: 2.628 ± 1.013
0.986ProGly: 0.986 ± 0.824
1.314ProHis: 1.314 ± 0.507
3.614ProIle: 3.614 ± 0.67
1.314ProLys: 1.314 ± 0.507
3.614ProLeu: 3.614 ± 0.714
1.314ProMet: 1.314 ± 0.641
0.986ProAsn: 0.986 ± 0.496
1.314ProPro: 1.314 ± 0.507
2.3ProGln: 2.3 ± 0.842
1.314ProArg: 1.314 ± 0.656
3.942ProSer: 3.942 ± 1.474
4.928ProThr: 4.928 ± 1.784
2.3ProVal: 2.3 ± 0.972
0.329ProTrp: 0.329 ± 0.164
2.628ProTyr: 2.628 ± 0.668
0.0ProXaa: 0.0 ± 0.0
Gln
4.271GlnAla: 4.271 ± 3.307
0.0GlnCys: 0.0 ± 0.0
1.314GlnAsp: 1.314 ± 0.656
1.643GlnGlu: 1.643 ± 1.065
0.986GlnPhe: 0.986 ± 0.859
2.628GlnGly: 2.628 ± 0.537
0.329GlnHis: 0.329 ± 0.164
3.942GlnIle: 3.942 ± 1.52
2.3GlnLys: 2.3 ± 1.321
3.614GlnLeu: 3.614 ± 1.331
2.3GlnMet: 2.3 ± 0.981
1.314GlnAsn: 1.314 ± 0.507
3.285GlnPro: 3.285 ± 2.037
3.285GlnGln: 3.285 ± 2.053
3.285GlnArg: 3.285 ± 1.137
2.628GlnSer: 2.628 ± 0.652
2.3GlnThr: 2.3 ± 1.56
2.3GlnVal: 2.3 ± 1.148
0.0GlnTrp: 0.0 ± 0.0
1.971GlnTyr: 1.971 ± 0.491
0.0GlnXaa: 0.0 ± 0.0
Arg
1.971ArgAla: 1.971 ± 0.645
1.314ArgCys: 1.314 ± 0.334
2.628ArgAsp: 2.628 ± 0.825
2.3ArgGlu: 2.3 ± 0.76
2.3ArgPhe: 2.3 ± 0.845
1.643ArgGly: 1.643 ± 0.552
1.971ArgHis: 1.971 ± 0.71
4.271ArgIle: 4.271 ± 1.394
2.957ArgLys: 2.957 ± 0.646
4.599ArgLeu: 4.599 ± 1.454
1.971ArgMet: 1.971 ± 1.185
3.942ArgAsn: 3.942 ± 0.978
1.314ArgPro: 1.314 ± 0.947
2.3ArgGln: 2.3 ± 0.704
2.957ArgArg: 2.957 ± 1.338
3.942ArgSer: 3.942 ± 1.33
2.3ArgThr: 2.3 ± 0.516
3.285ArgVal: 3.285 ± 0.773
1.314ArgTrp: 1.314 ± 0.656
1.643ArgTyr: 1.643 ± 0.843
0.0ArgXaa: 0.0 ± 0.0
Ser
2.957SerAla: 2.957 ± 1.332
0.986SerCys: 0.986 ± 0.462
2.628SerAsp: 2.628 ± 0.413
4.599SerGlu: 4.599 ± 0.681
2.628SerPhe: 2.628 ± 0.812
1.971SerGly: 1.971 ± 0.731
1.314SerHis: 1.314 ± 0.507
5.585SerIle: 5.585 ± 1.773
5.585SerLys: 5.585 ± 1.775
7.556SerLeu: 7.556 ± 2.263
1.971SerMet: 1.971 ± 1.137
3.614SerAsn: 3.614 ± 0.898
2.628SerPro: 2.628 ± 1.013
5.585SerGln: 5.585 ± 1.774
6.899SerArg: 6.899 ± 2.017
3.942SerSer: 3.942 ± 1.766
4.271SerThr: 4.271 ± 0.392
4.599SerVal: 4.599 ± 1.242
0.986SerTrp: 0.986 ± 0.492
2.3SerTyr: 2.3 ± 0.842
0.0SerXaa: 0.0 ± 0.0
Thr
5.256ThrAla: 5.256 ± 1.337
0.657ThrCys: 0.657 ± 0.328
5.913ThrAsp: 5.913 ± 1.474
3.942ThrGlu: 3.942 ± 1.965
2.3ThrPhe: 2.3 ± 0.445
3.614ThrGly: 3.614 ± 0.813
1.971ThrHis: 1.971 ± 1.061
4.271ThrIle: 4.271 ± 1.222
1.643ThrLys: 1.643 ± 0.82
5.913ThrLeu: 5.913 ± 1.245
1.643ThrMet: 1.643 ± 0.637
1.643ThrAsn: 1.643 ± 0.712
2.3ThrPro: 2.3 ± 1.449
1.643ThrGln: 1.643 ± 0.93
4.928ThrArg: 4.928 ± 0.576
4.599ThrSer: 4.599 ± 0.773
4.599ThrThr: 4.599 ± 1.551
3.614ThrVal: 3.614 ± 0.927
1.314ThrTrp: 1.314 ± 0.655
1.314ThrTyr: 1.314 ± 0.73
0.0ThrXaa: 0.0 ± 0.0
Val
2.3ValAla: 2.3 ± 2.261
0.657ValCys: 0.657 ± 0.328
4.271ValAsp: 4.271 ± 0.796
3.285ValGlu: 3.285 ± 1.168
0.986ValPhe: 0.986 ± 0.302
2.957ValGly: 2.957 ± 0.812
0.657ValHis: 0.657 ± 0.328
1.971ValIle: 1.971 ± 0.56
2.628ValLys: 2.628 ± 0.607
7.227ValLeu: 7.227 ± 1.771
1.643ValMet: 1.643 ± 1.0
2.957ValAsn: 2.957 ± 0.625
1.971ValPro: 1.971 ± 0.402
2.957ValGln: 2.957 ± 1.291
1.643ValArg: 1.643 ± 0.595
6.57ValSer: 6.57 ± 0.45
3.942ValThr: 3.942 ± 0.882
3.285ValVal: 3.285 ± 1.243
1.314ValTrp: 1.314 ± 0.655
1.643ValTyr: 1.643 ± 0.82
0.0ValXaa: 0.0 ± 0.0
Trp
1.314TrpAla: 1.314 ± 0.334
0.0TrpCys: 0.0 ± 0.0
0.657TrpAsp: 0.657 ± 0.328
1.643TrpGlu: 1.643 ± 0.921
0.657TrpPhe: 0.657 ± 0.328
0.329TrpGly: 0.329 ± 0.164
0.0TrpHis: 0.0 ± 0.0
1.314TrpIle: 1.314 ± 0.656
1.314TrpLys: 1.314 ± 0.655
0.657TrpLeu: 0.657 ± 0.328
0.329TrpMet: 0.329 ± 0.164
1.314TrpAsn: 1.314 ± 0.656
0.329TrpPro: 0.329 ± 0.164
0.657TrpGln: 0.657 ± 0.328
0.657TrpArg: 0.657 ± 0.328
0.329TrpSer: 0.329 ± 0.721
1.314TrpThr: 1.314 ± 0.656
0.657TrpVal: 0.657 ± 0.66
0.986TrpTrp: 0.986 ± 0.302
0.329TrpTyr: 0.329 ± 0.164
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.3TyrAla: 2.3 ± 0.486
0.329TyrCys: 0.329 ± 0.164
1.314TyrAsp: 1.314 ± 0.507
1.314TyrGlu: 1.314 ± 1.355
1.643TyrPhe: 1.643 ± 0.82
2.3TyrGly: 2.3 ± 0.704
1.643TyrHis: 1.643 ± 0.843
2.3TyrIle: 2.3 ± 0.907
1.643TyrLys: 1.643 ± 0.82
4.271TyrLeu: 4.271 ± 0.978
0.329TyrMet: 0.329 ± 0.17
2.3TyrAsn: 2.3 ± 1.291
3.285TyrPro: 3.285 ± 1.641
0.986TyrGln: 0.986 ± 0.462
2.3TyrArg: 2.3 ± 1.294
2.3TyrSer: 2.3 ± 0.486
3.285TyrThr: 3.285 ± 0.862
1.314TyrVal: 1.314 ± 0.656
0.986TyrTrp: 0.986 ± 0.462
2.3TyrTyr: 2.3 ± 1.148
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3045 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski