Amino acid dipepetide frequency for Corynebacterium camporealensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.599AlaAla: 14.599 ± 0.203	0.926AlaCys: 0.926 ± 0.039	7.073AlaAsp: 7.073 ± 0.11	8.338AlaGlu: 8.338 ± 0.122	3.636AlaPhe: 3.636 ± 0.079	9.508AlaGly: 9.508 ± 0.141	2.199AlaHis: 2.199 ± 0.056	5.648AlaIle: 5.648 ± 0.098	3.917AlaLys: 3.917 ± 0.086	11.141AlaLeu: 11.141 ± 0.145	2.698AlaMet: 2.698 ± 0.066	2.992AlaAsn: 2.992 ± 0.072	4.958AlaPro: 4.958 ± 0.154	4.444AlaGln: 4.444 ± 0.086	6.489AlaArg: 6.489 ± 0.111	5.724AlaSer: 5.724 ± 0.089	6.238AlaThr: 6.238 ± 0.096	8.951AlaVal: 8.951 ± 0.136	1.505AlaTrp: 1.505 ± 0.047	2.308AlaTyr: 2.308 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.827CysAla: 0.827 ± 0.033	0.069CysCys: 0.069 ± 0.012	0.437CysAsp: 0.437 ± 0.025	0.433CysGlu: 0.433 ± 0.028	0.248CysPhe: 0.248 ± 0.02	0.738CysGly: 0.738 ± 0.033	0.175CysHis: 0.175 ± 0.015	0.344CysIle: 0.344 ± 0.022	0.178CysLys: 0.178 ± 0.015	0.578CysLeu: 0.578 ± 0.03	0.157CysMet: 0.157 ± 0.015	0.176CysAsn: 0.176 ± 0.015	0.443CysPro: 0.443 ± 0.029	0.258CysGln: 0.258 ± 0.019	0.361CysArg: 0.361 ± 0.024	0.469CysSer: 0.469 ± 0.024	0.447CysThr: 0.447 ± 0.026	0.511CysVal: 0.511 ± 0.025	0.073CysTrp: 0.073 ± 0.01	0.137CysTyr: 0.137 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.323AspAla: 7.323 ± 0.11	0.407AspCys: 0.407 ± 0.023	4.435AspAsp: 4.435 ± 0.086	4.886AspGlu: 4.886 ± 0.089	2.336AspPhe: 2.336 ± 0.062	4.989AspGly: 4.989 ± 0.1	1.226AspHis: 1.226 ± 0.047	3.526AspIle: 3.526 ± 0.076	2.457AspLys: 2.457 ± 0.064	5.598AspLeu: 5.598 ± 0.086	1.415AspMet: 1.415 ± 0.041	2.222AspAsn: 2.222 ± 0.06	3.556AspPro: 3.556 ± 0.07	1.704AspGln: 1.704 ± 0.046	3.23AspArg: 3.23 ± 0.072	3.417AspSer: 3.417 ± 0.074	3.293AspThr: 3.293 ± 0.075	4.814AspVal: 4.814 ± 0.088	0.87AspTrp: 0.87 ± 0.033	1.771AspTyr: 1.771 ± 0.057	0.0AspXaa: 0.0 ± 0.0
Glu	7.058GluAla: 7.058 ± 0.112	0.409GluCys: 0.409 ± 0.023	4.229GluAsp: 4.229 ± 0.093	5.666GluGlu: 5.666 ± 0.128	2.233GluPhe: 2.233 ± 0.063	4.85GluGly: 4.85 ± 0.101	1.726GluHis: 1.726 ± 0.057	3.422GluIle: 3.422 ± 0.072	2.736GluLys: 2.736 ± 0.067	7.324GluLeu: 7.324 ± 0.12	1.466GluMet: 1.466 ± 0.042	2.154GluAsn: 2.154 ± 0.049	3.17GluPro: 3.17 ± 0.096	2.827GluGln: 2.827 ± 0.065	4.118GluArg: 4.118 ± 0.082	3.51GluSer: 3.51 ± 0.08	3.463GluThr: 3.463 ± 0.07	5.38GluVal: 5.38 ± 0.099	0.888GluTrp: 0.888 ± 0.034	1.546GluTyr: 1.546 ± 0.048	0.0GluXaa: 0.0 ± 0.0
Phe	3.869PheAla: 3.869 ± 0.074	0.283PheCys: 0.283 ± 0.021	2.453PheAsp: 2.453 ± 0.059	1.891PheGlu: 1.891 ± 0.057	1.306PhePhe: 1.306 ± 0.045	3.476PheGly: 3.476 ± 0.076	0.748PheHis: 0.748 ± 0.033	1.871PheIle: 1.871 ± 0.056	0.911PheLys: 0.911 ± 0.034	3.055PheLeu: 3.055 ± 0.086	0.736PheMet: 0.736 ± 0.03	1.109PheAsn: 1.109 ± 0.04	1.483PhePro: 1.483 ± 0.051	1.013PheGln: 1.013 ± 0.037	1.707PheArg: 1.707 ± 0.049	2.2PheSer: 2.2 ± 0.06	1.974PheThr: 1.974 ± 0.051	2.518PheVal: 2.518 ± 0.066	0.487PheTrp: 0.487 ± 0.031	0.842PheTyr: 0.842 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	8.464GlyAla: 8.464 ± 0.136	0.682GlyCys: 0.682 ± 0.034	4.629GlyAsp: 4.629 ± 0.091	5.406GlyGlu: 5.406 ± 0.091	3.209GlyPhe: 3.209 ± 0.077	6.623GlyGly: 6.623 ± 0.137	1.848GlyHis: 1.848 ± 0.055	4.859GlyIle: 4.859 ± 0.079	3.348GlyLys: 3.348 ± 0.068	7.91GlyLeu: 7.91 ± 0.102	2.167GlyMet: 2.167 ± 0.062	2.587GlyAsn: 2.587 ± 0.059	3.289GlyPro: 3.289 ± 0.081	2.851GlyGln: 2.851 ± 0.071	4.465GlyArg: 4.465 ± 0.082	4.615GlySer: 4.615 ± 0.077	5.029GlyThr: 5.029 ± 0.082	6.553GlyVal: 6.553 ± 0.085	1.361GlyTrp: 1.361 ± 0.047	2.263GlyTyr: 2.263 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	2.102HisAla: 2.102 ± 0.067	0.194HisCys: 0.194 ± 0.015	1.359HisAsp: 1.359 ± 0.043	1.203HisGlu: 1.203 ± 0.041	0.675HisPhe: 0.675 ± 0.032	1.874HisGly: 1.874 ± 0.053	0.613HisHis: 0.613 ± 0.039	1.06HisIle: 1.06 ± 0.039	0.556HisLys: 0.556 ± 0.027	2.111HisLeu: 2.111 ± 0.061	0.426HisMet: 0.426 ± 0.021	0.75HisAsn: 0.75 ± 0.03	1.5HisPro: 1.5 ± 0.049	0.685HisGln: 0.685 ± 0.033	1.369HisArg: 1.369 ± 0.041	1.181HisSer: 1.181 ± 0.042	1.26HisThr: 1.26 ± 0.043	1.501HisVal: 1.501 ± 0.046	0.24HisTrp: 0.24 ± 0.017	0.526HisTyr: 0.526 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	6.5IleAla: 6.5 ± 0.116	0.411IleCys: 0.411 ± 0.025	3.871IleAsp: 3.871 ± 0.073	3.288IleGlu: 3.288 ± 0.073	1.711IlePhe: 1.711 ± 0.056	4.583IleGly: 4.583 ± 0.092	0.986IleHis: 0.986 ± 0.035	2.781IleIle: 2.781 ± 0.082	1.453IleLys: 1.453 ± 0.044	4.253IleLeu: 4.253 ± 0.087	0.995IleMet: 0.995 ± 0.041	1.687IleAsn: 1.687 ± 0.049	2.614IlePro: 2.614 ± 0.061	1.371IleGln: 1.371 ± 0.042	2.605IleArg: 2.605 ± 0.068	3.007IleSer: 3.007 ± 0.067	3.166IleThr: 3.166 ± 0.068	4.385IleVal: 4.385 ± 0.089	0.59IleTrp: 0.59 ± 0.029	1.151IleTyr: 1.151 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	3.7LysAla: 3.7 ± 0.077	0.132LysCys: 0.132 ± 0.014	2.08LysAsp: 2.08 ± 0.061	2.336LysGlu: 2.336 ± 0.067	0.971LysPhe: 0.971 ± 0.038	2.337LysGly: 2.337 ± 0.055	0.831LysHis: 0.831 ± 0.033	1.608LysIle: 1.608 ± 0.052	1.944LysLys: 1.944 ± 0.071	3.353LysLeu: 3.353 ± 0.071	0.778LysMet: 0.778 ± 0.036	1.131LysAsn: 1.131 ± 0.038	1.836LysPro: 1.836 ± 0.057	1.544LysGln: 1.544 ± 0.056	2.276LysArg: 2.276 ± 0.057	1.761LysSer: 1.761 ± 0.052	1.89LysThr: 1.89 ± 0.061	2.657LysVal: 2.657 ± 0.066	0.462LysTrp: 0.462 ± 0.028	0.77LysTyr: 0.77 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	11.436LeuAla: 11.436 ± 0.146	0.715LeuCys: 0.715 ± 0.032	6.268LeuAsp: 6.268 ± 0.093	5.693LeuGlu: 5.693 ± 0.096	2.994LeuPhe: 2.994 ± 0.097	8.212LeuGly: 8.212 ± 0.12	1.989LeuHis: 1.989 ± 0.056	4.88LeuIle: 4.88 ± 0.095	2.648LeuLys: 2.648 ± 0.065	9.127LeuLeu: 9.127 ± 0.154	1.843LeuMet: 1.843 ± 0.051	3.026LeuAsn: 3.026 ± 0.066	5.193LeuPro: 5.193 ± 0.082	3.109LeuGln: 3.109 ± 0.072	6.435LeuArg: 6.435 ± 0.095	6.046LeuSer: 6.046 ± 0.103	5.422LeuThr: 5.422 ± 0.091	7.603LeuVal: 7.603 ± 0.11	1.133LeuTrp: 1.133 ± 0.047	1.933LeuTyr: 1.933 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.659MetAla: 2.659 ± 0.063	0.159MetCys: 0.159 ± 0.016	1.224MetAsp: 1.224 ± 0.042	1.242MetGlu: 1.242 ± 0.047	0.721MetPhe: 0.721 ± 0.032	1.773MetGly: 1.773 ± 0.056	0.456MetHis: 0.456 ± 0.027	1.028MetIle: 1.028 ± 0.044	0.728MetLys: 0.728 ± 0.029	2.375MetLeu: 2.375 ± 0.06	0.496MetMet: 0.496 ± 0.029	0.682MetAsn: 0.682 ± 0.029	1.194MetPro: 1.194 ± 0.048	0.723MetGln: 0.723 ± 0.033	1.348MetArg: 1.348 ± 0.044	1.699MetSer: 1.699 ± 0.052	1.661MetThr: 1.661 ± 0.048	1.666MetVal: 1.666 ± 0.053	0.282MetTrp: 0.282 ± 0.022	0.423MetTyr: 0.423 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	3.238AsnAla: 3.238 ± 0.065	0.216AsnCys: 0.216 ± 0.018	1.959AsnAsp: 1.959 ± 0.051	1.867AsnGlu: 1.867 ± 0.051	1.072AsnPhe: 1.072 ± 0.04	2.5AsnGly: 2.5 ± 0.062	0.672AsnHis: 0.672 ± 0.029	1.532AsnIle: 1.532 ± 0.046	1.041AsnLys: 1.041 ± 0.038	2.916AsnLeu: 2.916 ± 0.057	0.686AsnMet: 0.686 ± 0.032	1.121AsnAsn: 1.121 ± 0.044	2.243AsnPro: 2.243 ± 0.063	1.138AsnGln: 1.138 ± 0.04	1.74AsnArg: 1.74 ± 0.056	1.868AsnSer: 1.868 ± 0.048	1.788AsnThr: 1.788 ± 0.051	2.248AsnVal: 2.248 ± 0.059	0.446AsnTrp: 0.446 ± 0.026	0.919AsnTyr: 0.919 ± 0.037	0.0AsnXaa: 0.0 ± 0.0
Pro	5.597ProAla: 5.597 ± 0.121	0.259ProCys: 0.259 ± 0.021	3.464ProAsp: 3.464 ± 0.085	4.692ProGlu: 4.692 ± 0.104	1.593ProPhe: 1.593 ± 0.039	4.295ProGly: 4.295 ± 0.088	1.089ProHis: 1.089 ± 0.037	2.068ProIle: 2.068 ± 0.061	1.7ProLys: 1.7 ± 0.052	4.348ProLeu: 4.348 ± 0.079	0.952ProMet: 0.952 ± 0.039	1.551ProAsn: 1.551 ± 0.053	1.832ProPro: 1.832 ± 0.077	2.043ProGln: 2.043 ± 0.067	2.642ProArg: 2.642 ± 0.059	2.71ProSer: 2.71 ± 0.072	3.177ProThr: 3.177 ± 0.064	4.221ProVal: 4.221 ± 0.08	0.731ProTrp: 0.731 ± 0.034	1.059ProTyr: 1.059 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	4.185GlnAla: 4.185 ± 0.083	0.167GlnCys: 0.167 ± 0.017	1.931GlnAsp: 1.931 ± 0.048	2.263GlnGlu: 2.263 ± 0.057	1.062GlnPhe: 1.062 ± 0.04	2.489GlnGly: 2.489 ± 0.06	0.797GlnHis: 0.797 ± 0.03	1.565GlnIle: 1.565 ± 0.041	1.132GlnLys: 1.132 ± 0.045	4.058GlnLeu: 4.058 ± 0.088	0.864GlnMet: 0.864 ± 0.03	0.95GlnAsn: 0.95 ± 0.038	1.852GlnPro: 1.852 ± 0.061	1.796GlnGln: 1.796 ± 0.064	2.809GlnArg: 2.809 ± 0.072	1.612GlnSer: 1.612 ± 0.047	1.571GlnThr: 1.571 ± 0.044	2.741GlnVal: 2.741 ± 0.061	0.607GlnTrp: 0.607 ± 0.03	0.709GlnTyr: 0.709 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	6.017ArgAla: 6.017 ± 0.094	0.344ArgCys: 0.344 ± 0.023	3.632ArgAsp: 3.632 ± 0.076	4.298ArgGlu: 4.298 ± 0.089	1.982ArgPhe: 1.982 ± 0.055	4.24ArgGly: 4.24 ± 0.085	1.219ArgHis: 1.219 ± 0.045	3.166ArgIle: 3.166 ± 0.073	2.332ArgLys: 2.332 ± 0.059	5.395ArgLeu: 5.395 ± 0.093	1.619ArgMet: 1.619 ± 0.055	2.022ArgAsn: 2.022 ± 0.054	2.827ArgPro: 2.827 ± 0.06	2.125ArgGln: 2.125 ± 0.056	4.462ArgArg: 4.462 ± 0.109	3.24ArgSer: 3.24 ± 0.09	3.453ArgThr: 3.453 ± 0.072	4.363ArgVal: 4.363 ± 0.094	0.865ArgTrp: 0.865 ± 0.034	1.582ArgTyr: 1.582 ± 0.052	0.0ArgXaa: 0.0 ± 0.0
Ser	6.329SerAla: 6.329 ± 0.105	0.344SerCys: 0.344 ± 0.022	3.316SerAsp: 3.316 ± 0.077	3.605SerGlu: 3.605 ± 0.082	2.125SerPhe: 2.125 ± 0.055	5.049SerGly: 5.049 ± 0.08	1.113SerHis: 1.113 ± 0.043	2.714SerIle: 2.714 ± 0.073	1.898SerLys: 1.898 ± 0.059	5.176SerLeu: 5.176 ± 0.093	1.403SerMet: 1.403 ± 0.047	1.801SerAsn: 1.801 ± 0.055	2.754SerPro: 2.754 ± 0.064	2.07SerGln: 2.07 ± 0.055	3.277SerArg: 3.277 ± 0.078	3.506SerSer: 3.506 ± 0.092	3.727SerThr: 3.727 ± 0.066	4.211SerVal: 4.211 ± 0.083	0.869SerTrp: 0.869 ± 0.031	1.357SerTyr: 1.357 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	6.439ThrAla: 6.439 ± 0.092	0.43ThrCys: 0.43 ± 0.027	3.377ThrAsp: 3.377 ± 0.077	3.505ThrGlu: 3.505 ± 0.074	1.997ThrPhe: 1.997 ± 0.051	5.305ThrGly: 5.305 ± 0.083	1.147ThrHis: 1.147 ± 0.039	2.983ThrIle: 2.983 ± 0.076	1.955ThrLys: 1.955 ± 0.053	5.434ThrLeu: 5.434 ± 0.089	1.327ThrMet: 1.327 ± 0.036	1.706ThrAsn: 1.706 ± 0.043	3.509ThrPro: 3.509 ± 0.069	1.871ThrGln: 1.871 ± 0.053	3.152ThrArg: 3.152 ± 0.066	3.182ThrSer: 3.182 ± 0.063	3.611ThrThr: 3.611 ± 0.077	5.018ThrVal: 5.018 ± 0.087	0.874ThrTrp: 0.874 ± 0.033	1.483ThrTyr: 1.483 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	9.116ValAla: 9.116 ± 0.136	0.603ValCys: 0.603 ± 0.026	5.444ValAsp: 5.444 ± 0.102	5.327ValGlu: 5.327 ± 0.103	2.541ValPhe: 2.541 ± 0.072	6.303ValGly: 6.303 ± 0.105	1.597ValHis: 1.597 ± 0.047	4.497ValIle: 4.497 ± 0.08	2.291ValLys: 2.291 ± 0.062	7.742ValLeu: 7.742 ± 0.131	1.702ValMet: 1.702 ± 0.052	2.309ValAsn: 2.309 ± 0.06	3.869ValPro: 3.869 ± 0.073	2.15ValGln: 2.15 ± 0.058	4.355ValArg: 4.355 ± 0.08	4.576ValSer: 4.576 ± 0.085	4.992ValThr: 4.992 ± 0.088	6.889ValVal: 6.889 ± 0.128	0.946ValTrp: 0.946 ± 0.033	1.653ValTyr: 1.653 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	1.509TrpAla: 1.509 ± 0.049	0.104TrpCys: 0.104 ± 0.013	0.748TrpAsp: 0.748 ± 0.03	0.824TrpGlu: 0.824 ± 0.032	0.561TrpPhe: 0.561 ± 0.028	0.96TrpGly: 0.96 ± 0.042	0.289TrpHis: 0.289 ± 0.022	0.805TrpIle: 0.805 ± 0.036	0.525TrpLys: 0.525 ± 0.026	1.411TrpLeu: 1.411 ± 0.045	0.378TrpMet: 0.378 ± 0.021	0.464TrpAsn: 0.464 ± 0.029	0.666TrpPro: 0.666 ± 0.031	0.575TrpGln: 0.575 ± 0.029	0.838TrpArg: 0.838 ± 0.031	0.767TrpSer: 0.767 ± 0.034	0.789TrpThr: 0.789 ± 0.034	1.06TrpVal: 1.06 ± 0.034	0.334TrpTrp: 0.334 ± 0.021	0.304TrpTyr: 0.304 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.327TyrAla: 2.327 ± 0.058	0.205TyrCys: 0.205 ± 0.017	1.548TyrAsp: 1.548 ± 0.045	1.411TyrGlu: 1.411 ± 0.045	0.96TyrPhe: 0.96 ± 0.036	2.053TyrGly: 2.053 ± 0.055	0.462TyrHis: 0.462 ± 0.025	1.048TyrIle: 1.048 ± 0.043	0.648TyrLys: 0.648 ± 0.033	2.398TyrLeu: 2.398 ± 0.054	0.43TyrMet: 0.43 ± 0.027	0.771TyrAsn: 0.771 ± 0.033	1.235TyrPro: 1.235 ± 0.046	0.865TyrGln: 0.865 ± 0.033	1.506TyrArg: 1.506 ± 0.052	1.554TyrSer: 1.554 ± 0.045	1.354TyrThr: 1.354 ± 0.048	1.612TyrVal: 1.612 ± 0.051	0.347TyrTrp: 0.347 ± 0.022	0.598TyrTyr: 0.598 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2245 proteins (737566 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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