Amino acid dipepetide frequency for Sauropus yellowing virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.954AlaAla: 3.954 ± 1.283
0.659AlaCys: 0.659 ± 0.492
1.318AlaAsp: 1.318 ± 0.334
3.295AlaGlu: 3.295 ± 1.485
1.647AlaPhe: 1.647 ± 0.483
5.601AlaGly: 5.601 ± 1.476
0.988AlaHis: 0.988 ± 0.455
3.624AlaIle: 3.624 ± 0.945
1.647AlaLys: 1.647 ± 0.889
6.919AlaLeu: 6.919 ± 1.127
1.647AlaMet: 1.647 ± 0.607
1.977AlaAsn: 1.977 ± 0.888
2.965AlaPro: 2.965 ± 1.366
3.954AlaGln: 3.954 ± 0.489
3.295AlaArg: 3.295 ± 0.572
6.26AlaSer: 6.26 ± 1.231
2.306AlaThr: 2.306 ± 1.357
7.249AlaVal: 7.249 ± 2.137
0.0AlaTrp: 0.0 ± 0.0
2.636AlaTyr: 2.636 ± 1.156
0.0AlaXaa: 0.0 ± 0.0
Cys
1.647CysAla: 1.647 ± 0.888
0.0CysCys: 0.0 ± 0.0
1.647CysAsp: 1.647 ± 0.741
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.647CysGly: 1.647 ± 0.518
0.0CysHis: 0.0 ± 0.0
1.318CysIle: 1.318 ± 0.334
2.306CysLys: 2.306 ± 0.624
1.977CysLeu: 1.977 ± 0.758
0.659CysMet: 0.659 ± 0.312
0.988CysAsn: 0.988 ± 0.274
0.329CysPro: 0.329 ± 0.334
0.329CysGln: 0.329 ± 0.522
0.329CysArg: 0.329 ± 0.468
0.659CysSer: 0.659 ± 0.492
1.647CysThr: 1.647 ± 0.483
1.318CysVal: 1.318 ± 0.88
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.295AspAla: 3.295 ± 0.927
0.988AspCys: 0.988 ± 0.601
3.954AspAsp: 3.954 ± 0.758
3.295AspGlu: 3.295 ± 0.878
1.647AspPhe: 1.647 ± 0.518
3.295AspGly: 3.295 ± 0.65
0.988AspHis: 0.988 ± 0.453
2.306AspIle: 2.306 ± 0.764
0.988AspLys: 0.988 ± 0.274
4.283AspLeu: 4.283 ± 0.629
0.659AspMet: 0.659 ± 0.315
2.636AspAsn: 2.636 ± 0.926
1.318AspPro: 1.318 ± 0.703
1.977AspGln: 1.977 ± 0.694
1.977AspArg: 1.977 ± 1.23
3.624AspSer: 3.624 ± 1.288
2.306AspThr: 2.306 ± 0.546
1.977AspVal: 1.977 ± 1.075
0.988AspTrp: 0.988 ± 0.455
2.965AspTyr: 2.965 ± 1.205
0.0AspXaa: 0.0 ± 0.0
Glu
2.965GluAla: 2.965 ± 0.762
0.329GluCys: 0.329 ± 0.522
2.306GluAsp: 2.306 ± 1.148
2.965GluGlu: 2.965 ± 0.651
1.977GluPhe: 1.977 ± 0.91
3.624GluGly: 3.624 ± 1.074
0.659GluHis: 0.659 ± 0.483
3.295GluIle: 3.295 ± 0.459
4.942GluLys: 4.942 ± 0.904
3.624GluLeu: 3.624 ± 1.287
1.318GluMet: 1.318 ± 0.334
0.988GluAsn: 0.988 ± 0.521
2.636GluPro: 2.636 ± 1.051
2.636GluGln: 2.636 ± 0.671
2.965GluArg: 2.965 ± 0.762
5.931GluSer: 5.931 ± 0.856
6.59GluThr: 6.59 ± 1.016
3.954GluVal: 3.954 ± 1.386
0.988GluTrp: 0.988 ± 0.607
0.988GluTyr: 0.988 ± 0.808
0.0GluXaa: 0.0 ± 0.0
Phe
2.306PheAla: 2.306 ± 0.725
0.988PheCys: 0.988 ± 0.455
3.954PheAsp: 3.954 ± 1.119
2.636PheGlu: 2.636 ± 0.85
0.659PhePhe: 0.659 ± 0.589
3.295PheGly: 3.295 ± 0.999
0.329PheHis: 0.329 ± 0.468
1.647PheIle: 1.647 ± 1.393
1.318PheLys: 1.318 ± 0.519
4.613PheLeu: 4.613 ± 1.101
0.329PheMet: 0.329 ± 0.334
2.965PheAsn: 2.965 ± 1.349
3.624PhePro: 3.624 ± 0.551
2.306PheGln: 2.306 ± 0.54
2.965PheArg: 2.965 ± 1.051
1.977PheSer: 1.977 ± 1.245
3.295PheThr: 3.295 ± 0.759
3.954PheVal: 3.954 ± 1.387
0.0PheTrp: 0.0 ± 0.0
0.329PheTyr: 0.329 ± 0.468
0.0PheXaa: 0.0 ± 0.0
Gly
3.624GlyAla: 3.624 ± 0.419
1.977GlyCys: 1.977 ± 0.707
4.283GlyAsp: 4.283 ± 0.807
3.954GlyGlu: 3.954 ± 0.936
3.624GlyPhe: 3.624 ± 0.897
4.942GlyGly: 4.942 ± 1.443
0.988GlyHis: 0.988 ± 0.453
3.295GlyIle: 3.295 ± 1.306
5.272GlyLys: 5.272 ± 0.84
5.931GlyLeu: 5.931 ± 0.811
0.0GlyMet: 0.0 ± 0.0
5.601GlyAsn: 5.601 ± 1.715
1.647GlyPro: 1.647 ± 0.624
3.624GlyGln: 3.624 ± 1.164
7.249GlyArg: 7.249 ± 2.909
6.26GlySer: 6.26 ± 1.757
3.954GlyThr: 3.954 ± 0.763
3.954GlyVal: 3.954 ± 0.882
0.988GlyTrp: 0.988 ± 0.607
3.295GlyTyr: 3.295 ± 1.149
0.0GlyXaa: 0.0 ± 0.0
His
0.659HisAla: 0.659 ± 0.937
1.647HisCys: 1.647 ± 0.649
1.318HisAsp: 1.318 ± 0.919
1.318HisGlu: 1.318 ± 0.665
1.318HisPhe: 1.318 ± 0.519
0.988HisGly: 0.988 ± 0.512
0.0HisHis: 0.0 ± 0.0
0.988HisIle: 0.988 ± 0.938
1.318HisLys: 1.318 ± 0.662
0.988HisLeu: 0.988 ± 0.607
0.329HisMet: 0.329 ± 0.468
1.647HisAsn: 1.647 ± 0.528
0.329HisPro: 0.329 ± 0.246
0.659HisGln: 0.659 ± 0.312
0.659HisArg: 0.659 ± 0.312
3.954HisSer: 3.954 ± 1.051
0.329HisThr: 0.329 ± 0.33
0.659HisVal: 0.659 ± 0.312
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.624IleAla: 3.624 ± 0.701
0.329IleCys: 0.329 ± 0.468
0.988IleAsp: 0.988 ± 0.795
4.283IleGlu: 4.283 ± 1.669
1.647IlePhe: 1.647 ± 1.447
0.329IleGly: 0.329 ± 0.33
0.659IleHis: 0.659 ± 0.312
1.647IleIle: 1.647 ± 0.674
1.977IleLys: 1.977 ± 0.732
3.295IleLeu: 3.295 ± 1.244
0.659IleMet: 0.659 ± 0.315
1.318IleAsn: 1.318 ± 0.468
6.59IlePro: 6.59 ± 1.737
3.295IleGln: 3.295 ± 0.835
3.295IleArg: 3.295 ± 1.131
3.295IleSer: 3.295 ± 0.846
1.977IleThr: 1.977 ± 0.534
1.647IleVal: 1.647 ± 0.624
1.977IleTrp: 1.977 ± 0.937
2.965IleTyr: 2.965 ± 0.694
0.0IleXaa: 0.0 ± 0.0
Lys
3.624LysAla: 3.624 ± 1.863
0.0LysCys: 0.0 ± 0.0
2.636LysAsp: 2.636 ± 0.923
0.659LysGlu: 0.659 ± 0.483
2.965LysPhe: 2.965 ± 0.881
5.272LysGly: 5.272 ± 1.914
0.659LysHis: 0.659 ± 0.312
2.965LysIle: 2.965 ± 1.262
1.647LysLys: 1.647 ± 0.889
5.931LysLeu: 5.931 ± 1.107
0.988LysMet: 0.988 ± 0.563
1.977LysAsn: 1.977 ± 0.758
2.965LysPro: 2.965 ± 1.205
3.295LysGln: 3.295 ± 1.297
3.954LysArg: 3.954 ± 1.156
5.931LysSer: 5.931 ± 0.863
1.977LysThr: 1.977 ± 0.548
2.636LysVal: 2.636 ± 0.671
1.647LysTrp: 1.647 ± 0.528
0.659LysTyr: 0.659 ± 0.315
0.329LysXaa: 0.329 ± 0.334
Leu
6.59LeuAla: 6.59 ± 1.97
3.295LeuCys: 3.295 ± 1.297
3.624LeuAsp: 3.624 ± 1.426
4.942LeuGlu: 4.942 ± 0.961
6.59LeuPhe: 6.59 ± 1.983
4.613LeuGly: 4.613 ± 0.78
2.636LeuHis: 2.636 ± 0.623
2.306LeuIle: 2.306 ± 1.042
6.26LeuLys: 6.26 ± 1.247
9.226LeuLeu: 9.226 ± 1.221
2.306LeuMet: 2.306 ± 1.634
0.659LeuAsn: 0.659 ± 0.312
4.613LeuPro: 4.613 ± 1.401
2.636LeuGln: 2.636 ± 1.259
7.578LeuArg: 7.578 ± 1.659
10.873LeuSer: 10.873 ± 2.273
4.942LeuThr: 4.942 ± 1.09
6.59LeuVal: 6.59 ± 2.246
1.647LeuTrp: 1.647 ± 0.674
3.295LeuTyr: 3.295 ± 0.63
0.0LeuXaa: 0.0 ± 0.0
Met
1.318MetAla: 1.318 ± 0.358
0.329MetCys: 0.329 ± 0.246
0.659MetAsp: 0.659 ± 0.399
2.636MetGlu: 2.636 ± 0.909
0.0MetPhe: 0.0 ± 0.0
0.988MetGly: 0.988 ± 1.018
0.329MetHis: 0.329 ± 0.246
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.647MetLeu: 1.647 ± 0.518
0.0MetMet: 0.0 ± 0.0
0.988MetAsn: 0.988 ± 0.764
0.329MetPro: 0.329 ± 0.468
0.329MetGln: 0.329 ± 0.468
1.318MetArg: 1.318 ± 0.456
0.988MetSer: 0.988 ± 0.633
0.0MetThr: 0.0 ± 0.0
2.965MetVal: 2.965 ± 0.332
0.0MetTrp: 0.0 ± 0.0
0.659MetTyr: 0.659 ± 0.312
0.0MetXaa: 0.0 ± 0.0
Asn
0.659AsnAla: 0.659 ± 0.937
0.659AsnCys: 0.659 ± 0.312
0.0AsnAsp: 0.0 ± 0.0
1.977AsnGlu: 1.977 ± 0.757
1.647AsnPhe: 1.647 ± 0.507
7.578AsnGly: 7.578 ± 1.696
0.329AsnHis: 0.329 ± 0.522
1.977AsnIle: 1.977 ± 0.734
2.306AsnLys: 2.306 ± 0.54
4.613AsnLeu: 4.613 ± 0.766
0.0AsnMet: 0.0 ± 0.229
3.295AsnAsn: 3.295 ± 0.574
1.647AsnPro: 1.647 ± 0.794
0.329AsnGln: 0.329 ± 0.334
5.272AsnArg: 5.272 ± 1.993
2.636AsnSer: 2.636 ± 1.063
3.954AsnThr: 3.954 ± 0.489
1.647AsnVal: 1.647 ± 0.975
0.988AsnTrp: 0.988 ± 0.524
1.647AsnTyr: 1.647 ± 0.741
0.0AsnXaa: 0.0 ± 0.0
Pro
1.977ProAla: 1.977 ± 1.187
0.329ProCys: 0.329 ± 0.334
2.306ProAsp: 2.306 ± 1.042
3.624ProGlu: 3.624 ± 0.807
0.659ProPhe: 0.659 ± 0.483
4.613ProGly: 4.613 ± 1.232
1.977ProHis: 1.977 ± 0.629
4.283ProIle: 4.283 ± 1.084
3.624ProLys: 3.624 ± 0.661
4.283ProLeu: 4.283 ± 1.114
0.988ProMet: 0.988 ± 0.524
2.306ProAsn: 2.306 ± 1.561
6.919ProPro: 6.919 ± 3.073
1.318ProGln: 1.318 ± 0.572
1.977ProArg: 1.977 ± 1.078
3.295ProSer: 3.295 ± 0.564
2.636ProThr: 2.636 ± 1.307
4.613ProVal: 4.613 ± 0.933
0.988ProTrp: 0.988 ± 0.601
0.988ProTyr: 0.988 ± 0.455
0.0ProXaa: 0.0 ± 0.0
Gln
4.613GlnAla: 4.613 ± 0.981
0.329GlnCys: 0.329 ± 0.246
0.659GlnAsp: 0.659 ± 0.315
1.318GlnGlu: 1.318 ± 0.572
1.318GlnPhe: 1.318 ± 0.468
1.318GlnGly: 1.318 ± 0.468
0.0GlnHis: 0.0 ± 0.0
0.988GlnIle: 0.988 ± 0.721
1.977GlnLys: 1.977 ± 0.791
3.624GlnLeu: 3.624 ± 1.181
0.988GlnMet: 0.988 ± 0.952
1.318GlnAsn: 1.318 ± 0.983
3.295GlnPro: 3.295 ± 1.249
2.636GlnGln: 2.636 ± 0.536
3.624GlnArg: 3.624 ± 2.03
4.283GlnSer: 4.283 ± 0.824
0.988GlnThr: 0.988 ± 0.274
0.988GlnVal: 0.988 ± 0.455
0.988GlnTrp: 0.988 ± 0.601
1.977GlnTyr: 1.977 ± 0.438
0.0GlnXaa: 0.0 ± 0.0
Arg
3.295ArgAla: 3.295 ± 1.442
0.0ArgCys: 0.0 ± 0.0
2.306ArgAsp: 2.306 ± 1.113
2.636ArgGlu: 2.636 ± 0.624
4.613ArgPhe: 4.613 ± 1.9
7.578ArgGly: 7.578 ± 3.451
2.306ArgHis: 2.306 ± 0.464
2.306ArgIle: 2.306 ± 0.548
4.613ArgLys: 4.613 ± 1.227
7.249ArgLeu: 7.249 ± 1.596
0.0ArgMet: 0.0 ± 0.0
3.954ArgAsn: 3.954 ± 1.748
1.977ArgPro: 1.977 ± 0.757
3.295ArgGln: 3.295 ± 1.505
8.237ArgArg: 8.237 ± 1.804
4.283ArgSer: 4.283 ± 2.267
3.954ArgThr: 3.954 ± 1.091
2.965ArgVal: 2.965 ± 0.989
1.647ArgTrp: 1.647 ± 0.345
2.965ArgTyr: 2.965 ± 0.818
0.0ArgXaa: 0.0 ± 0.0
Ser
6.26SerAla: 6.26 ± 1.423
2.636SerCys: 2.636 ± 0.721
3.954SerAsp: 3.954 ± 1.571
6.59SerGlu: 6.59 ± 2.733
3.954SerPhe: 3.954 ± 1.814
6.26SerGly: 6.26 ± 1.507
2.965SerHis: 2.965 ± 0.546
3.954SerIle: 3.954 ± 1.079
4.613SerLys: 4.613 ± 1.823
7.908SerLeu: 7.908 ± 2.059
0.329SerMet: 0.329 ± 0.33
3.954SerAsn: 3.954 ± 1.414
5.601SerPro: 5.601 ± 1.426
0.0SerGln: 0.0 ± 0.0
4.283SerArg: 4.283 ± 1.743
10.214SerSer: 10.214 ± 2.015
5.931SerThr: 5.931 ± 2.976
6.919SerVal: 6.919 ± 0.667
1.977SerTrp: 1.977 ± 0.758
1.318SerTyr: 1.318 ± 0.529
0.0SerXaa: 0.0 ± 0.0
Thr
4.283ThrAla: 4.283 ± 2.535
0.659ThrCys: 0.659 ± 0.312
1.977ThrAsp: 1.977 ± 0.569
2.306ThrGlu: 2.306 ± 0.671
4.283ThrPhe: 4.283 ± 1.01
3.295ThrGly: 3.295 ± 0.575
0.329ThrHis: 0.329 ± 0.246
4.942ThrIle: 4.942 ± 2.245
3.295ThrLys: 3.295 ± 1.097
4.283ThrLeu: 4.283 ± 1.043
0.988ThrMet: 0.988 ± 0.757
0.988ThrAsn: 0.988 ± 0.593
4.613ThrPro: 4.613 ± 0.555
0.988ThrGln: 0.988 ± 0.601
3.954ThrArg: 3.954 ± 0.826
4.942ThrSer: 4.942 ± 1.987
6.59ThrThr: 6.59 ± 1.316
4.613ThrVal: 4.613 ± 0.993
0.659ThrTrp: 0.659 ± 0.312
2.636ThrTyr: 2.636 ± 0.538
0.0ThrXaa: 0.0 ± 0.0
Val
3.954ValAla: 3.954 ± 1.108
1.318ValCys: 1.318 ± 0.867
4.283ValAsp: 4.283 ± 0.405
3.954ValGlu: 3.954 ± 1.004
1.977ValPhe: 1.977 ± 0.629
5.601ValGly: 5.601 ± 1.138
0.988ValHis: 0.988 ± 0.747
2.636ValIle: 2.636 ± 0.931
1.647ValLys: 1.647 ± 0.345
9.226ValLeu: 9.226 ± 2.348
1.977ValMet: 1.977 ± 0.694
3.954ValAsn: 3.954 ± 0.695
1.647ValPro: 1.647 ± 0.961
1.647ValGln: 1.647 ± 1.076
3.624ValArg: 3.624 ± 0.945
7.249ValSer: 7.249 ± 1.917
2.965ValThr: 2.965 ± 1.051
4.613ValVal: 4.613 ± 1.717
2.306ValTrp: 2.306 ± 0.48
1.647ValTyr: 1.647 ± 0.837
0.0ValXaa: 0.0 ± 0.0
Trp
1.318TrpAla: 1.318 ± 0.662
0.0TrpCys: 0.0 ± 0.0
1.647TrpAsp: 1.647 ± 0.837
1.318TrpGlu: 1.318 ± 0.358
1.318TrpPhe: 1.318 ± 0.526
0.659TrpGly: 0.659 ± 0.483
0.659TrpHis: 0.659 ± 0.589
0.659TrpIle: 0.659 ± 0.483
0.988TrpLys: 0.988 ± 0.455
1.977TrpLeu: 1.977 ± 0.48
0.988TrpMet: 0.988 ± 0.455
0.329TrpAsn: 0.329 ± 0.246
0.329TrpPro: 0.329 ± 0.246
0.0TrpGln: 0.0 ± 0.0
1.977TrpArg: 1.977 ± 0.871
1.647TrpSer: 1.647 ± 0.708
0.329TrpThr: 0.329 ± 0.522
1.977TrpVal: 1.977 ± 0.757
0.329TrpTrp: 0.329 ± 0.468
0.329TrpTyr: 0.329 ± 0.468
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.977TyrAla: 1.977 ± 0.521
0.329TyrCys: 0.329 ± 0.334
1.647TyrAsp: 1.647 ± 0.837
1.977TyrGlu: 1.977 ± 0.983
1.647TyrPhe: 1.647 ± 0.837
2.965TyrGly: 2.965 ± 0.981
1.318TyrHis: 1.318 ± 0.545
0.659TyrIle: 0.659 ± 0.315
1.977TyrLys: 1.977 ± 1.017
3.624TyrLeu: 3.624 ± 1.18
0.0TyrMet: 0.0 ± 0.0
1.647TyrAsn: 1.647 ± 0.518
0.329TyrPro: 0.329 ± 0.246
1.977TyrGln: 1.977 ± 0.758
1.647TyrArg: 1.647 ± 0.518
1.318TyrSer: 1.318 ± 1.377
3.954TyrThr: 3.954 ± 0.753
1.647TyrVal: 1.647 ± 0.741
0.659TyrTrp: 0.659 ± 0.315
1.647TyrTyr: 1.647 ± 0.788
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.329XaaVal: 0.329 ± 0.334
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3036 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski