Amino acid dipepetide frequency for Roseivivax jejudonensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.154AlaAla: 20.154 ± 0.25	1.138AlaCys: 1.138 ± 0.033	7.837AlaAsp: 7.837 ± 0.09	9.428AlaGlu: 9.428 ± 0.112	4.489AlaPhe: 4.489 ± 0.061	11.869AlaGly: 11.869 ± 0.117	2.51AlaHis: 2.51 ± 0.054	5.613AlaIle: 5.613 ± 0.064	2.667AlaLys: 2.667 ± 0.05	14.828AlaLeu: 14.828 ± 0.167	3.793AlaMet: 3.793 ± 0.067	2.287AlaAsn: 2.287 ± 0.044	7.09AlaPro: 7.09 ± 0.099	4.1AlaGln: 4.1 ± 0.068	11.163AlaArg: 11.163 ± 0.171	5.458AlaSer: 5.458 ± 0.074	6.627AlaThr: 6.627 ± 0.084	8.993AlaVal: 8.993 ± 0.104	1.629AlaTrp: 1.629 ± 0.035	2.477AlaTyr: 2.477 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	1.123CysAla: 1.123 ± 0.031	0.109CysCys: 0.109 ± 0.01	0.615CysAsp: 0.615 ± 0.022	0.379CysGlu: 0.379 ± 0.02	0.299CysPhe: 0.299 ± 0.016	0.928CysGly: 0.928 ± 0.028	0.26CysHis: 0.26 ± 0.015	0.36CysIle: 0.36 ± 0.019	0.144CysLys: 0.144 ± 0.01	0.891CysLeu: 0.891 ± 0.028	0.16CysMet: 0.16 ± 0.012	0.198CysAsn: 0.198 ± 0.014	0.463CysPro: 0.463 ± 0.021	0.178CysGln: 0.178 ± 0.013	0.594CysArg: 0.594 ± 0.022	0.377CysSer: 0.377 ± 0.017	0.411CysThr: 0.411 ± 0.019	0.607CysVal: 0.607 ± 0.022	0.103CysTrp: 0.103 ± 0.009	0.184CysTyr: 0.184 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	8.962AspAla: 8.962 ± 0.107	0.461AspCys: 0.461 ± 0.022	4.307AspAsp: 4.307 ± 0.15	3.71AspGlu: 3.71 ± 0.055	2.243AspPhe: 2.243 ± 0.057	6.597AspGly: 6.597 ± 0.122	1.382AspHis: 1.382 ± 0.034	3.03AspIle: 3.03 ± 0.056	1.201AspLys: 1.201 ± 0.033	6.615AspLeu: 6.615 ± 0.077	1.607AspMet: 1.607 ± 0.031	1.159AspAsn: 1.159 ± 0.041	4.164AspPro: 4.164 ± 0.075	1.472AspGln: 1.472 ± 0.038	5.266AspArg: 5.266 ± 0.08	2.322AspSer: 2.322 ± 0.056	3.64AspThr: 3.64 ± 0.076	4.566AspVal: 4.566 ± 0.061	1.208AspTrp: 1.208 ± 0.029	1.522AspTyr: 1.522 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	9.044GluAla: 9.044 ± 0.119	0.366GluCys: 0.366 ± 0.017	3.841GluAsp: 3.841 ± 0.075	3.75GluGlu: 3.75 ± 0.065	1.693GluPhe: 1.693 ± 0.036	5.134GluGly: 5.134 ± 0.075	1.071GluHis: 1.071 ± 0.035	3.736GluIle: 3.736 ± 0.054	1.608GluLys: 1.608 ± 0.04	4.84GluLeu: 4.84 ± 0.071	1.912GluMet: 1.912 ± 0.044	1.452GluAsn: 1.452 ± 0.042	2.811GluPro: 2.811 ± 0.06	1.687GluGln: 1.687 ± 0.035	5.033GluArg: 5.033 ± 0.064	2.4GluSer: 2.4 ± 0.046	4.449GluThr: 4.449 ± 0.066	4.487GluVal: 4.487 ± 0.061	0.732GluTrp: 0.732 ± 0.024	1.021GluTyr: 1.021 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	4.621PheAla: 4.621 ± 0.065	0.4PheCys: 0.4 ± 0.017	2.885PheAsp: 2.885 ± 0.055	2.292PheGlu: 2.292 ± 0.052	1.314PhePhe: 1.314 ± 0.03	3.68PheGly: 3.68 ± 0.058	0.677PheHis: 0.677 ± 0.024	1.353PheIle: 1.353 ± 0.038	0.652PheLys: 0.652 ± 0.026	3.308PheLeu: 3.308 ± 0.065	0.754PheMet: 0.754 ± 0.024	0.869PheAsn: 0.869 ± 0.029	1.515PhePro: 1.515 ± 0.033	0.829PheGln: 0.829 ± 0.027	2.364PheArg: 2.364 ± 0.047	1.839PheSer: 1.839 ± 0.034	1.911PheThr: 1.911 ± 0.043	2.873PheVal: 2.873 ± 0.055	0.533PheTrp: 0.533 ± 0.022	0.86PheTyr: 0.86 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	11.39GlyAla: 11.39 ± 0.113	0.818GlyCys: 0.818 ± 0.028	5.522GlyAsp: 5.522 ± 0.123	4.812GlyGlu: 4.812 ± 0.074	3.507GlyPhe: 3.507 ± 0.057	8.302GlyGly: 8.302 ± 0.163	1.985GlyHis: 1.985 ± 0.043	4.42GlyIle: 4.42 ± 0.072	2.164GlyLys: 2.164 ± 0.051	9.212GlyLeu: 9.212 ± 0.107	2.41GlyMet: 2.41 ± 0.046	1.938GlyAsn: 1.938 ± 0.065	4.263GlyPro: 4.263 ± 0.065	2.862GlyGln: 2.862 ± 0.053	6.918GlyArg: 6.918 ± 0.085	4.321GlySer: 4.321 ± 0.09	5.285GlyThr: 5.285 ± 0.1	6.487GlyVal: 6.487 ± 0.084	1.522GlyTrp: 1.522 ± 0.036	2.272GlyTyr: 2.272 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.554HisAla: 2.554 ± 0.055	0.192HisCys: 0.192 ± 0.013	1.378HisAsp: 1.378 ± 0.04	1.087HisGlu: 1.087 ± 0.03	0.774HisPhe: 0.774 ± 0.027	1.998HisGly: 1.998 ± 0.044	0.533HisHis: 0.533 ± 0.025	0.768HisIle: 0.768 ± 0.024	0.355HisLys: 0.355 ± 0.019	2.023HisLeu: 2.023 ± 0.044	0.487HisMet: 0.487 ± 0.019	0.386HisAsn: 0.386 ± 0.018	1.315HisPro: 1.315 ± 0.033	0.482HisGln: 0.482 ± 0.02	1.457HisArg: 1.457 ± 0.036	0.771HisSer: 0.771 ± 0.026	0.789HisThr: 0.789 ± 0.027	1.702HisVal: 1.702 ± 0.042	0.336HisTrp: 0.336 ± 0.017	0.494HisTyr: 0.494 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	6.927IleAla: 6.927 ± 0.077	0.503IleCys: 0.503 ± 0.019	3.548IleAsp: 3.548 ± 0.061	3.338IleGlu: 3.338 ± 0.052	1.593IlePhe: 1.593 ± 0.041	4.66IleGly: 4.66 ± 0.069	0.832IleHis: 0.832 ± 0.027	1.542IleIle: 1.542 ± 0.043	0.917IleLys: 0.917 ± 0.03	4.567IleLeu: 4.567 ± 0.07	0.876IleMet: 0.876 ± 0.028	1.065IleAsn: 1.065 ± 0.033	2.064IlePro: 2.064 ± 0.051	0.965IleGln: 0.965 ± 0.028	3.226IleArg: 3.226 ± 0.054	2.291IleSer: 2.291 ± 0.047	2.347IleThr: 2.347 ± 0.043	3.919IleVal: 3.919 ± 0.062	0.635IleTrp: 0.635 ± 0.022	1.044IleTyr: 1.044 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	2.823LysAla: 2.823 ± 0.055	0.153LysCys: 0.153 ± 0.01	1.312LysAsp: 1.312 ± 0.033	1.116LysGlu: 1.116 ± 0.034	0.613LysPhe: 0.613 ± 0.027	1.804LysGly: 1.804 ± 0.042	0.437LysHis: 0.437 ± 0.019	1.137LysIle: 1.137 ± 0.032	0.822LysLys: 0.822 ± 0.035	2.077LysLeu: 2.077 ± 0.049	0.636LysMet: 0.636 ± 0.024	0.526LysAsn: 0.526 ± 0.02	1.291LysPro: 1.291 ± 0.034	0.584LysGln: 0.584 ± 0.022	1.808LysArg: 1.808 ± 0.043	1.348LysSer: 1.348 ± 0.043	1.479LysThr: 1.479 ± 0.037	1.629LysVal: 1.629 ± 0.044	0.279LysTrp: 0.279 ± 0.016	0.438LysTyr: 0.438 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	13.557LeuAla: 13.557 ± 0.167	0.984LeuCys: 0.984 ± 0.027	6.573LeuAsp: 6.573 ± 0.078	5.433LeuGlu: 5.433 ± 0.072	3.463LeuPhe: 3.463 ± 0.063	8.732LeuGly: 8.732 ± 0.1	1.766LeuHis: 1.766 ± 0.04	4.462LeuIle: 4.462 ± 0.072	2.296LeuLys: 2.296 ± 0.048	8.56LeuLeu: 8.56 ± 0.128	2.435LeuMet: 2.435 ± 0.049	2.135LeuAsn: 2.135 ± 0.04	5.554LeuPro: 5.554 ± 0.062	2.368LeuGln: 2.368 ± 0.043	7.55LeuArg: 7.55 ± 0.092	6.578LeuSer: 6.578 ± 0.075	5.662LeuThr: 5.662 ± 0.073	7.477LeuVal: 7.477 ± 0.088	1.399LeuTrp: 1.399 ± 0.034	1.887LeuTyr: 1.887 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	3.188MetAla: 3.188 ± 0.055	0.178MetCys: 0.178 ± 0.011	1.315MetAsp: 1.315 ± 0.032	1.222MetGlu: 1.222 ± 0.028	0.731MetPhe: 0.731 ± 0.026	2.003MetGly: 2.003 ± 0.046	0.484MetHis: 0.484 ± 0.021	1.351MetIle: 1.351 ± 0.037	0.811MetLys: 0.811 ± 0.026	2.414MetLeu: 2.414 ± 0.046	0.62MetMet: 0.62 ± 0.023	0.703MetAsn: 0.703 ± 0.024	1.539MetPro: 1.539 ± 0.038	0.882MetGln: 0.882 ± 0.026	2.012MetArg: 2.012 ± 0.049	1.734MetSer: 1.734 ± 0.031	2.075MetThr: 2.075 ± 0.037	1.61MetVal: 1.61 ± 0.038	0.24MetTrp: 0.24 ± 0.016	0.304MetTyr: 0.304 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.899AsnAla: 2.899 ± 0.05	0.193AsnCys: 0.193 ± 0.011	1.408AsnAsp: 1.408 ± 0.067	1.062AsnGlu: 1.062 ± 0.028	0.796AsnPhe: 0.796 ± 0.027	2.047AsnGly: 2.047 ± 0.055	0.411AsnHis: 0.411 ± 0.017	1.035AsnIle: 1.035 ± 0.034	0.41AsnLys: 0.41 ± 0.02	2.066AsnLeu: 2.066 ± 0.04	0.537AsnMet: 0.537 ± 0.023	0.505AsnAsn: 0.505 ± 0.027	1.494AsnPro: 1.494 ± 0.035	0.555AsnGln: 0.555 ± 0.023	1.569AsnArg: 1.569 ± 0.037	0.888AsnSer: 0.888 ± 0.033	1.088AsnThr: 1.088 ± 0.037	1.723AsnVal: 1.723 ± 0.046	0.336AsnTrp: 0.336 ± 0.015	0.581AsnTyr: 0.581 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	6.584ProAla: 6.584 ± 0.092	0.343ProCys: 0.343 ± 0.016	4.631ProAsp: 4.631 ± 0.066	4.663ProGlu: 4.663 ± 0.075	1.932ProPhe: 1.932 ± 0.036	5.098ProGly: 5.098 ± 0.074	1.084ProHis: 1.084 ± 0.029	2.098ProIle: 2.098 ± 0.044	1.216ProLys: 1.216 ± 0.032	4.712ProLeu: 4.712 ± 0.07	1.158ProMet: 1.158 ± 0.031	1.152ProAsn: 1.152 ± 0.036	2.597ProPro: 2.597 ± 0.055	1.468ProGln: 1.468 ± 0.036	3.403ProArg: 3.403 ± 0.071	2.482ProSer: 2.482 ± 0.043	2.379ProThr: 2.379 ± 0.041	4.415ProVal: 4.415 ± 0.064	0.706ProTrp: 0.706 ± 0.023	1.078ProTyr: 1.078 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.487GlnAla: 3.487 ± 0.055	0.19GlnCys: 0.19 ± 0.014	1.586GlnAsp: 1.586 ± 0.045	1.493GlnGlu: 1.493 ± 0.042	0.886GlnPhe: 0.886 ± 0.025	2.254GlnGly: 2.254 ± 0.049	0.494GlnHis: 0.494 ± 0.017	1.667GlnIle: 1.667 ± 0.043	0.744GlnLys: 0.744 ± 0.027	2.32GlnLeu: 2.32 ± 0.051	0.836GlnMet: 0.836 ± 0.027	0.706GlnAsn: 0.706 ± 0.023	1.419GlnPro: 1.419 ± 0.031	0.907GlnGln: 0.907 ± 0.04	2.067GlnArg: 2.067 ± 0.044	1.648GlnSer: 1.648 ± 0.043	1.6GlnThr: 1.6 ± 0.035	2.147GlnVal: 2.147 ± 0.041	0.321GlnTrp: 0.321 ± 0.017	0.488GlnTyr: 0.488 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	10.226ArgAla: 10.226 ± 0.144	0.483ArgCys: 0.483 ± 0.02	5.123ArgAsp: 5.123 ± 0.084	4.336ArgGlu: 4.336 ± 0.065	2.897ArgPhe: 2.897 ± 0.05	5.465ArgGly: 5.465 ± 0.077	1.802ArgHis: 1.802 ± 0.046	4.16ArgIle: 4.16 ± 0.071	1.73ArgLys: 1.73 ± 0.039	8.188ArgLeu: 8.188 ± 0.106	2.057ArgMet: 2.057 ± 0.038	1.603ArgAsn: 1.603 ± 0.038	3.994ArgPro: 3.994 ± 0.073	2.183ArgGln: 2.183 ± 0.046	6.522ArgArg: 6.522 ± 0.107	3.461ArgSer: 3.461 ± 0.059	3.547ArgThr: 3.547 ± 0.05	5.437ArgVal: 5.437 ± 0.071	1.072ArgTrp: 1.072 ± 0.031	1.659ArgTyr: 1.659 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	6.01SerAla: 6.01 ± 0.075	0.398SerCys: 0.398 ± 0.019	3.416SerAsp: 3.416 ± 0.072	3.113SerGlu: 3.113 ± 0.053	1.978SerPhe: 1.978 ± 0.037	5.523SerGly: 5.523 ± 0.099	0.956SerHis: 0.956 ± 0.026	2.151SerIle: 2.151 ± 0.051	1.118SerLys: 1.118 ± 0.033	4.594SerLeu: 4.594 ± 0.062	1.188SerMet: 1.188 ± 0.033	1.123SerAsn: 1.123 ± 0.033	2.322SerPro: 2.322 ± 0.047	1.348SerGln: 1.348 ± 0.036	3.354SerArg: 3.354 ± 0.054	2.272SerSer: 2.272 ± 0.049	2.316SerThr: 2.316 ± 0.047	3.807SerVal: 3.807 ± 0.06	0.637SerTrp: 0.637 ± 0.025	1.201SerTyr: 1.201 ± 0.03	0.0SerXaa: 0.0 ± 0.0
Thr	6.604ThrAla: 6.604 ± 0.094	0.473ThrCys: 0.473 ± 0.021	3.596ThrAsp: 3.596 ± 0.066	3.337ThrGlu: 3.337 ± 0.054	2.09ThrPhe: 2.09 ± 0.053	5.657ThrGly: 5.657 ± 0.08	1.072ThrHis: 1.072 ± 0.028	2.61ThrIle: 2.61 ± 0.051	1.07ThrLys: 1.07 ± 0.033	6.451ThrLeu: 6.451 ± 0.079	1.213ThrMet: 1.213 ± 0.039	1.121ThrAsn: 1.121 ± 0.038	3.398ThrPro: 3.398 ± 0.047	1.413ThrGln: 1.413 ± 0.036	3.847ThrArg: 3.847 ± 0.056	2.467ThrSer: 2.467 ± 0.049	2.772ThrThr: 2.772 ± 0.069	4.282ThrVal: 4.282 ± 0.087	0.782ThrTrp: 0.782 ± 0.027	1.182ThrTyr: 1.182 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	9.956ValAla: 9.956 ± 0.104	0.627ValCys: 0.627 ± 0.022	4.199ValAsp: 4.199 ± 0.071	4.589ValGlu: 4.589 ± 0.073	2.876ValPhe: 2.876 ± 0.053	5.575ValGly: 5.575 ± 0.081	1.338ValHis: 1.338 ± 0.038	3.858ValIle: 3.858 ± 0.05	1.63ValLys: 1.63 ± 0.043	7.425ValLeu: 7.425 ± 0.073	1.905ValMet: 1.905 ± 0.036	1.793ValAsn: 1.793 ± 0.038	4.101ValPro: 4.101 ± 0.057	1.846ValGln: 1.846 ± 0.04	4.89ValArg: 4.89 ± 0.06	4.326ValSer: 4.326 ± 0.052	5.116ValThr: 5.116 ± 0.093	5.848ValVal: 5.848 ± 0.085	1.037ValTrp: 1.037 ± 0.028	1.463ValTyr: 1.463 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.452TrpAla: 1.452 ± 0.039	0.143TrpCys: 0.143 ± 0.009	0.775TrpAsp: 0.775 ± 0.026	0.661TrpGlu: 0.661 ± 0.024	0.529TrpPhe: 0.529 ± 0.02	1.026TrpGly: 1.026 ± 0.029	0.34TrpHis: 0.34 ± 0.016	0.744TrpIle: 0.744 ± 0.025	0.341TrpLys: 0.341 ± 0.015	1.64TrpLeu: 1.64 ± 0.043	0.412TrpMet: 0.412 ± 0.018	0.365TrpAsn: 0.365 ± 0.018	0.783TrpPro: 0.783 ± 0.028	0.566TrpGln: 0.566 ± 0.02	1.273TrpArg: 1.273 ± 0.032	0.813TrpSer: 0.813 ± 0.024	0.886TrpThr: 0.886 ± 0.026	0.866TrpVal: 0.866 ± 0.026	0.224TrpTrp: 0.224 ± 0.012	0.245TrpTyr: 0.245 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.593TyrAla: 2.593 ± 0.052	0.229TyrCys: 0.229 ± 0.014	1.565TyrAsp: 1.565 ± 0.032	1.248TyrGlu: 1.248 ± 0.038	0.828TyrPhe: 0.828 ± 0.023	2.056TyrGly: 2.056 ± 0.048	0.451TyrHis: 0.451 ± 0.021	0.764TyrIle: 0.764 ± 0.026	0.416TyrLys: 0.416 ± 0.021	2.14TyrLeu: 2.14 ± 0.042	0.419TyrMet: 0.419 ± 0.018	0.517TyrAsn: 0.517 ± 0.02	1.022TyrPro: 1.022 ± 0.03	0.566TyrGln: 0.566 ± 0.025	1.628TyrArg: 1.628 ± 0.033	1.026TyrSer: 1.026 ± 0.028	1.056TyrThr: 1.056 ± 0.033	1.521TyrVal: 1.521 ± 0.037	0.354TyrTrp: 0.354 ± 0.018	0.543TyrTyr: 0.543 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4082 proteins (1278265 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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