Amino acid dipepetide frequency for Porcine picobirnavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.289AlaAla: 8.289 ± 4.133
0.754AlaCys: 0.754 ± 0.589
5.275AlaAsp: 5.275 ± 1.606
5.275AlaGlu: 5.275 ± 1.223
0.754AlaPhe: 0.754 ± 0.516
3.014AlaGly: 3.014 ± 1.361
0.754AlaHis: 0.754 ± 0.589
4.521AlaIle: 4.521 ± 0.779
1.507AlaLys: 1.507 ± 0.26
5.275AlaLeu: 5.275 ± 2.071
5.275AlaMet: 5.275 ± 2.823
5.275AlaAsn: 5.275 ± 0.854
1.507AlaPro: 1.507 ± 1.031
5.275AlaGln: 5.275 ± 1.92
5.275AlaArg: 5.275 ± 1.929
4.521AlaSer: 4.521 ± 1.811
3.768AlaThr: 3.768 ± 0.977
5.275AlaVal: 5.275 ± 0.912
0.0AlaTrp: 0.0 ± 0.0
4.521AlaTyr: 4.521 ± 0.779
0.0AlaXaa: 0.0 ± 0.0
Cys
0.754CysAla: 0.754 ± 0.516
0.0CysCys: 0.0 ± 0.0
0.754CysAsp: 0.754 ± 0.589
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.754CysIle: 0.754 ± 0.516
0.0CysLys: 0.0 ± 0.0
0.754CysLeu: 0.754 ± 0.589
1.507CysMet: 1.507 ± 1.178
1.507CysAsn: 1.507 ± 1.031
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.754CysArg: 0.754 ± 0.589
0.754CysSer: 0.754 ± 0.589
3.014CysThr: 3.014 ± 0.519
0.754CysVal: 0.754 ± 0.589
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.507AspAla: 1.507 ± 0.26
0.754AspCys: 0.754 ± 0.589
3.014AspAsp: 3.014 ± 1.324
3.768AspGlu: 3.768 ± 2.322
7.536AspPhe: 7.536 ± 1.426
2.261AspGly: 2.261 ± 0.751
0.754AspHis: 0.754 ± 0.516
4.521AspIle: 4.521 ± 0.779
5.275AspLys: 5.275 ± 0.232
4.521AspLeu: 4.521 ± 0.748
1.507AspMet: 1.507 ± 0.26
1.507AspAsn: 1.507 ± 1.031
2.261AspPro: 2.261 ± 0.565
3.014AspGln: 3.014 ± 1.051
2.261AspArg: 2.261 ± 0.565
2.261AspSer: 2.261 ± 1.547
4.521AspThr: 4.521 ± 1.439
5.275AspVal: 5.275 ± 0.232
1.507AspTrp: 1.507 ± 0.845
1.507AspTyr: 1.507 ± 1.178
0.0AspXaa: 0.0 ± 0.0
Glu
3.014GluAla: 3.014 ± 0.519
0.0GluCys: 0.0 ± 0.0
3.768GluAsp: 3.768 ± 0.341
4.521GluGlu: 4.521 ± 2.293
2.261GluPhe: 2.261 ± 0.56
3.768GluGly: 3.768 ± 0.341
1.507GluHis: 1.507 ± 0.26
1.507GluIle: 1.507 ± 0.26
1.507GluLys: 1.507 ± 1.031
3.768GluLeu: 3.768 ± 1.395
3.768GluMet: 3.768 ± 0.341
3.014GluAsn: 3.014 ± 1.324
2.261GluPro: 2.261 ± 0.751
3.768GluGln: 3.768 ± 1.263
2.261GluArg: 2.261 ± 1.277
4.521GluSer: 4.521 ± 3.18
5.275GluThr: 5.275 ± 2.875
5.275GluVal: 5.275 ± 0.232
0.0GluTrp: 0.0 ± 0.0
1.507GluTyr: 1.507 ± 0.845
0.0GluXaa: 0.0 ± 0.0
Phe
4.521PheAla: 4.521 ± 0.779
0.754PheCys: 0.754 ± 0.589
3.014PheAsp: 3.014 ± 0.519
0.754PheGlu: 0.754 ± 0.516
0.754PhePhe: 0.754 ± 0.589
2.261PheGly: 2.261 ± 0.751
0.0PheHis: 0.0 ± 0.0
1.507PheIle: 1.507 ± 0.89
0.0PheLys: 0.0 ± 0.0
1.507PheLeu: 1.507 ± 0.89
0.754PheMet: 0.754 ± 0.516
3.014PheAsn: 3.014 ± 0.519
0.754PhePro: 0.754 ± 0.589
0.0PheGln: 0.0 ± 0.0
2.261PheArg: 2.261 ± 0.565
2.261PheSer: 2.261 ± 0.565
2.261PheThr: 2.261 ± 0.751
2.261PheVal: 2.261 ± 0.565
0.0PheTrp: 0.0 ± 0.0
1.507PheTyr: 1.507 ± 1.031
0.0PheXaa: 0.0 ± 0.0
Gly
2.261GlyAla: 2.261 ± 1.146
0.0GlyCys: 0.0 ± 0.0
5.275GlyAsp: 5.275 ± 0.912
1.507GlyGlu: 1.507 ± 0.845
0.754GlyPhe: 0.754 ± 0.516
6.029GlyGly: 6.029 ± 0.803
0.754GlyHis: 0.754 ± 0.516
6.029GlyIle: 6.029 ± 0.891
4.521GlyLys: 4.521 ± 1.131
3.768GlyLeu: 3.768 ± 1.907
1.507GlyMet: 1.507 ± 0.26
1.507GlyAsn: 1.507 ± 1.031
1.507GlyPro: 1.507 ± 1.178
3.014GlyGln: 3.014 ± 0.78
3.768GlyArg: 3.768 ± 2.164
6.782GlySer: 6.782 ± 1.422
3.014GlyThr: 3.014 ± 0.607
9.043GlyVal: 9.043 ± 1.82
0.754GlyTrp: 0.754 ± 0.589
3.768GlyTyr: 3.768 ± 1.555
0.0GlyXaa: 0.0 ± 0.0
His
2.261HisAla: 2.261 ± 1.547
0.0HisCys: 0.0 ± 0.0
0.754HisAsp: 0.754 ± 0.516
0.0HisGlu: 0.0 ± 0.0
2.261HisPhe: 2.261 ± 1.768
3.014HisGly: 3.014 ± 0.519
0.754HisHis: 0.754 ± 0.589
0.0HisIle: 0.0 ± 0.0
0.754HisLys: 0.754 ± 0.589
0.754HisLeu: 0.754 ± 0.589
0.754HisMet: 0.754 ± 0.516
4.521HisAsn: 4.521 ± 4.823
1.507HisPro: 1.507 ± 0.26
0.754HisGln: 0.754 ± 0.516
0.754HisArg: 0.754 ± 0.589
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
2.261HisTyr: 2.261 ± 0.565
0.0HisXaa: 0.0 ± 0.0
Ile
4.521IleAla: 4.521 ± 0.396
1.507IleCys: 1.507 ± 0.26
2.261IleAsp: 2.261 ± 1.277
3.768IleGlu: 3.768 ± 2.322
0.754IlePhe: 0.754 ± 0.516
3.014IleGly: 3.014 ± 2.063
0.0IleHis: 0.0 ± 0.0
0.754IleIle: 0.754 ± 0.516
1.507IleLys: 1.507 ± 0.89
3.768IleLeu: 3.768 ± 1.907
0.754IleMet: 0.754 ± 0.516
3.014IleAsn: 3.014 ± 1.051
4.521IlePro: 4.521 ± 1.131
0.754IleGln: 0.754 ± 0.516
3.014IleArg: 3.014 ± 0.607
3.014IleSer: 3.014 ± 1.361
3.014IleThr: 3.014 ± 0.78
1.507IleVal: 1.507 ± 0.26
0.0IleTrp: 0.0 ± 0.0
4.521IleTyr: 4.521 ± 3.094
0.0IleXaa: 0.0 ± 0.0
Lys
6.029LysAla: 6.029 ± 1.26
0.754LysCys: 0.754 ± 0.516
3.014LysAsp: 3.014 ± 1.051
2.261LysGlu: 2.261 ± 0.56
1.507LysPhe: 1.507 ± 0.26
2.261LysGly: 2.261 ± 0.565
1.507LysHis: 1.507 ± 0.26
0.754LysIle: 0.754 ± 0.589
1.507LysLys: 1.507 ± 0.26
3.768LysLeu: 3.768 ± 0.977
0.0LysMet: 0.0 ± 0.507
1.507LysAsn: 1.507 ± 0.26
1.507LysPro: 1.507 ± 0.26
1.507LysGln: 1.507 ± 1.178
2.261LysArg: 2.261 ± 1.768
6.029LysSer: 6.029 ± 1.039
3.014LysThr: 3.014 ± 0.519
2.261LysVal: 2.261 ± 0.751
2.261LysTrp: 2.261 ± 0.56
6.029LysTyr: 6.029 ± 2.649
0.0LysXaa: 0.0 ± 0.0
Leu
4.521LeuAla: 4.521 ± 1.811
0.754LeuCys: 0.754 ± 0.516
3.768LeuAsp: 3.768 ± 0.341
3.768LeuGlu: 3.768 ± 1.263
0.0LeuPhe: 0.0 ± 0.0
6.782LeuGly: 6.782 ± 2.46
0.754LeuHis: 0.754 ± 0.516
3.768LeuIle: 3.768 ± 0.977
3.768LeuLys: 3.768 ± 1.263
5.275LeuLeu: 5.275 ± 1.929
1.507LeuMet: 1.507 ± 0.26
4.521LeuAsn: 4.521 ± 0.396
1.507LeuPro: 1.507 ± 0.26
3.768LeuGln: 3.768 ± 1.907
12.057LeuArg: 12.057 ± 3.424
6.029LeuSer: 6.029 ± 2.527
6.029LeuThr: 6.029 ± 1.354
3.768LeuVal: 3.768 ± 0.713
0.754LeuTrp: 0.754 ± 0.516
3.014LeuTyr: 3.014 ± 0.519
0.0LeuXaa: 0.0 ± 0.0
Met
3.768MetAla: 3.768 ± 2.578
0.754MetCys: 0.754 ± 0.516
1.507MetAsp: 1.507 ± 1.031
1.507MetGlu: 1.507 ± 1.178
0.754MetPhe: 0.754 ± 0.589
2.261MetGly: 2.261 ± 0.565
0.0MetHis: 0.0 ± 0.0
3.768MetIle: 3.768 ± 1.555
1.507MetLys: 1.507 ± 1.178
3.014MetLeu: 3.014 ± 1.564
0.0MetMet: 0.0 ± 0.0
1.507MetAsn: 1.507 ± 0.26
1.507MetPro: 1.507 ± 1.178
1.507MetGln: 1.507 ± 0.26
0.754MetArg: 0.754 ± 0.804
2.261MetSer: 2.261 ± 0.565
3.014MetThr: 3.014 ± 0.607
2.261MetVal: 2.261 ± 1.146
0.754MetTrp: 0.754 ± 0.516
0.754MetTyr: 0.754 ± 0.516
0.0MetXaa: 0.0 ± 0.0
Asn
3.014AsnAla: 3.014 ± 0.78
1.507AsnCys: 1.507 ± 0.26
2.261AsnAsp: 2.261 ± 0.751
1.507AsnGlu: 1.507 ± 1.031
2.261AsnPhe: 2.261 ± 1.146
3.014AsnGly: 3.014 ± 1.051
0.0AsnHis: 0.0 ± 0.0
3.014AsnIle: 3.014 ± 1.051
3.768AsnLys: 3.768 ± 1.555
3.014AsnLeu: 3.014 ± 0.78
2.261AsnMet: 2.261 ± 1.547
1.507AsnAsn: 1.507 ± 0.26
2.261AsnPro: 2.261 ± 0.751
1.507AsnGln: 1.507 ± 0.845
2.261AsnArg: 2.261 ± 1.59
5.275AsnSer: 5.275 ± 0.854
2.261AsnThr: 2.261 ± 0.565
6.782AsnVal: 6.782 ± 2.551
1.507AsnTrp: 1.507 ± 1.178
2.261AsnTyr: 2.261 ± 1.547
0.0AsnXaa: 0.0 ± 0.0
Pro
2.261ProAla: 2.261 ± 0.565
0.754ProCys: 0.754 ± 0.589
1.507ProAsp: 1.507 ± 0.26
0.754ProGlu: 0.754 ± 0.516
1.507ProPhe: 1.507 ± 1.178
2.261ProGly: 2.261 ± 0.565
0.754ProHis: 0.754 ± 0.589
0.754ProIle: 0.754 ± 0.589
3.768ProLys: 3.768 ± 0.713
5.275ProLeu: 5.275 ± 1.183
3.014ProMet: 3.014 ± 0.629
1.507ProAsn: 1.507 ± 0.26
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
0.754ProArg: 0.754 ± 0.516
3.768ProSer: 3.768 ± 0.956
1.507ProThr: 1.507 ± 0.26
3.768ProVal: 3.768 ± 2.578
0.0ProTrp: 0.0 ± 0.0
2.261ProTyr: 2.261 ± 0.751
0.0ProXaa: 0.0 ± 0.0
Gln
1.507GlnAla: 1.507 ± 0.89
0.754GlnCys: 0.754 ± 0.589
3.014GlnAsp: 3.014 ± 0.78
2.261GlnGlu: 2.261 ± 0.565
0.754GlnPhe: 0.754 ± 0.589
3.014GlnGly: 3.014 ± 2.343
1.507GlnHis: 1.507 ± 1.178
2.261GlnIle: 2.261 ± 1.146
1.507GlnLys: 1.507 ± 0.26
3.768GlnLeu: 3.768 ± 0.956
0.0GlnMet: 0.0 ± 0.0
2.261GlnAsn: 2.261 ± 0.565
1.507GlnPro: 1.507 ± 0.26
0.0GlnGln: 0.0 ± 0.0
3.014GlnArg: 3.014 ± 1.779
5.275GlnSer: 5.275 ± 3.041
3.014GlnThr: 3.014 ± 1.361
2.261GlnVal: 2.261 ± 1.567
1.507GlnTrp: 1.507 ± 1.031
3.768GlnTyr: 3.768 ± 0.713
0.0GlnXaa: 0.0 ± 0.0
Arg
6.029ArgAla: 6.029 ± 2.954
0.0ArgCys: 0.0 ± 0.0
3.768ArgAsp: 3.768 ± 1.907
3.768ArgGlu: 3.768 ± 1.307
0.754ArgPhe: 0.754 ± 0.589
3.768ArgGly: 3.768 ± 0.341
6.782ArgHis: 6.782 ± 4.701
4.521ArgIle: 4.521 ± 1.439
1.507ArgLys: 1.507 ± 0.26
8.289ArgLeu: 8.289 ± 1.517
0.754ArgMet: 0.754 ± 0.589
1.507ArgAsn: 1.507 ± 1.031
1.507ArgPro: 1.507 ± 1.031
3.768ArgGln: 3.768 ± 1.263
6.029ArgArg: 6.029 ± 1.213
4.521ArgSer: 4.521 ± 1.12
3.014ArgThr: 3.014 ± 0.78
0.754ArgVal: 0.754 ± 0.589
0.754ArgTrp: 0.754 ± 0.589
1.507ArgTyr: 1.507 ± 1.178
0.0ArgXaa: 0.0 ± 0.0
Ser
4.521SerAla: 4.521 ± 1.12
0.0SerCys: 0.0 ± 0.0
4.521SerAsp: 4.521 ± 1.439
6.782SerGlu: 6.782 ± 1.087
3.768SerPhe: 3.768 ± 1.555
9.797SerGly: 9.797 ± 0.98
0.754SerHis: 0.754 ± 0.589
5.275SerIle: 5.275 ± 1.223
5.275SerLys: 5.275 ± 1.183
2.261SerLeu: 2.261 ± 0.751
3.014SerMet: 3.014 ± 1.051
1.507SerAsn: 1.507 ± 0.845
1.507SerPro: 1.507 ± 0.26
6.029SerGln: 6.029 ± 1.825
5.275SerArg: 5.275 ± 1.048
6.782SerSer: 6.782 ± 2.46
5.275SerThr: 5.275 ± 3.454
2.261SerVal: 2.261 ± 0.751
0.0SerTrp: 0.0 ± 0.0
3.768SerTyr: 3.768 ± 2.578
0.0SerXaa: 0.0 ± 0.0
Thr
5.275ThrAla: 5.275 ± 0.854
1.507ThrCys: 1.507 ± 0.26
4.521ThrAsp: 4.521 ± 0.396
7.536ThrGlu: 7.536 ± 3.689
0.754ThrPhe: 0.754 ± 0.516
1.507ThrGly: 1.507 ± 1.031
0.0ThrHis: 0.0 ± 0.0
0.754ThrIle: 0.754 ± 0.589
3.014ThrLys: 3.014 ± 0.519
7.536ThrLeu: 7.536 ± 1.567
2.261ThrMet: 2.261 ± 1.146
6.029ThrAsn: 6.029 ± 1.039
3.768ThrPro: 3.768 ± 1.555
3.768ThrGln: 3.768 ± 1.395
3.014ThrArg: 3.014 ± 0.78
2.261ThrSer: 2.261 ± 0.565
4.521ThrThr: 4.521 ± 2.511
4.521ThrVal: 4.521 ± 0.779
0.754ThrTrp: 0.754 ± 0.589
3.014ThrTyr: 3.014 ± 0.519
0.0ThrXaa: 0.0 ± 0.0
Val
6.782ValAla: 6.782 ± 2.54
0.754ValCys: 0.754 ± 0.589
2.261ValAsp: 2.261 ± 0.565
4.521ValGlu: 4.521 ± 1.653
0.754ValPhe: 0.754 ± 0.516
3.768ValGly: 3.768 ± 1.395
1.507ValHis: 1.507 ± 1.031
0.754ValIle: 0.754 ± 0.516
6.029ValLys: 6.029 ± 2.649
3.768ValLeu: 3.768 ± 0.713
0.754ValMet: 0.754 ± 0.516
3.768ValAsn: 3.768 ± 1.555
3.768ValPro: 3.768 ± 0.977
2.261ValGln: 2.261 ± 1.567
3.014ValArg: 3.014 ± 0.519
6.782ValSer: 6.782 ± 3.584
5.275ValThr: 5.275 ± 2.578
5.275ValVal: 5.275 ± 1.183
0.754ValTrp: 0.754 ± 0.589
4.521ValTyr: 4.521 ± 1.501
0.0ValXaa: 0.0 ± 0.0
Trp
0.754TrpAla: 0.754 ± 0.804
0.0TrpCys: 0.0 ± 0.0
1.507TrpAsp: 1.507 ± 0.26
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.754TrpHis: 0.754 ± 0.589
0.754TrpIle: 0.754 ± 0.589
1.507TrpLys: 1.507 ± 0.26
0.754TrpLeu: 0.754 ± 0.589
1.507TrpMet: 1.507 ± 0.26
0.0TrpAsn: 0.0 ± 0.0
0.754TrpPro: 0.754 ± 0.589
0.0TrpGln: 0.0 ± 0.0
0.754TrpArg: 0.754 ± 0.589
0.0TrpSer: 0.0 ± 0.0
0.754TrpThr: 0.754 ± 0.516
0.0TrpVal: 0.0 ± 0.0
0.754TrpTrp: 0.754 ± 0.589
2.261TrpTyr: 2.261 ± 1.146
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.521TyrAla: 4.521 ± 0.779
0.0TyrCys: 0.0 ± 0.0
3.768TyrAsp: 3.768 ± 0.713
3.014TyrGlu: 3.014 ± 0.519
2.261TyrPhe: 2.261 ± 1.768
3.768TyrGly: 3.768 ± 2.578
2.261TyrHis: 2.261 ± 0.751
0.0TyrIle: 0.0 ± 0.0
2.261TyrLys: 2.261 ± 0.751
5.275TyrLeu: 5.275 ± 0.912
1.507TyrMet: 1.507 ± 0.26
2.261TyrAsn: 2.261 ± 1.146
2.261TyrPro: 2.261 ± 0.751
2.261TyrGln: 2.261 ± 0.751
3.768TyrArg: 3.768 ± 0.341
5.275TyrSer: 5.275 ± 2.578
3.768TyrThr: 3.768 ± 1.555
3.768TyrVal: 3.768 ± 2.578
0.754TyrTrp: 0.754 ± 0.589
3.014TyrTyr: 3.014 ± 1.051
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1328 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski