Amino acid dipepetide frequency for Tissierellia bacterium S5-A11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.124AlaAla: 7.124 ± 0.162	0.924AlaCys: 0.924 ± 0.032	4.278AlaAsp: 4.278 ± 0.083	4.769AlaGlu: 4.769 ± 0.093	3.059AlaPhe: 3.059 ± 0.073	6.001AlaGly: 6.001 ± 0.111	1.476AlaHis: 1.476 ± 0.048	5.477AlaIle: 5.477 ± 0.099	5.396AlaLys: 5.396 ± 0.098	9.102AlaLeu: 9.102 ± 0.138	2.403AlaMet: 2.403 ± 0.06	2.764AlaAsn: 2.764 ± 0.056	2.493AlaPro: 2.493 ± 0.061	3.691AlaGln: 3.691 ± 0.085	3.894AlaArg: 3.894 ± 0.077	3.935AlaSer: 3.935 ± 0.071	3.773AlaThr: 3.773 ± 0.075	5.314AlaVal: 5.314 ± 0.113	0.663AlaTrp: 0.663 ± 0.028	2.885AlaTyr: 2.885 ± 0.058	0.0AlaXaa: 0.0 ± 0.0
Cys	0.677CysAla: 0.677 ± 0.032	0.111CysCys: 0.111 ± 0.012	0.522CysAsp: 0.522 ± 0.028	0.479CysGlu: 0.479 ± 0.029	0.337CysPhe: 0.337 ± 0.021	0.924CysGly: 0.924 ± 0.037	0.248CysHis: 0.248 ± 0.016	0.65CysIle: 0.65 ± 0.028	0.467CysLys: 0.467 ± 0.027	1.041CysLeu: 1.041 ± 0.037	0.222CysMet: 0.222 ± 0.017	0.342CysAsn: 0.342 ± 0.02	0.467CysPro: 0.467 ± 0.025	0.403CysGln: 0.403 ± 0.021	0.449CysArg: 0.449 ± 0.024	0.473CysSer: 0.473 ± 0.025	0.403CysThr: 0.403 ± 0.023	0.633CysVal: 0.633 ± 0.031	0.066CysTrp: 0.066 ± 0.01	0.352CysTyr: 0.352 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	3.999AspAla: 3.999 ± 0.083	0.515AspCys: 0.515 ± 0.025	2.737AspAsp: 2.737 ± 0.072	4.056AspGlu: 4.056 ± 0.081	3.017AspPhe: 3.017 ± 0.055	4.049AspGly: 4.049 ± 0.077	1.339AspHis: 1.339 ± 0.046	4.135AspIle: 4.135 ± 0.071	3.794AspLys: 3.794 ± 0.098	7.548AspLeu: 7.548 ± 0.135	1.465AspMet: 1.465 ± 0.036	1.88AspAsn: 1.88 ± 0.052	2.486AspPro: 2.486 ± 0.056	3.031AspGln: 3.031 ± 0.075	3.097AspArg: 3.097 ± 0.068	2.648AspSer: 2.648 ± 0.067	2.545AspThr: 2.545 ± 0.05	3.772AspVal: 3.772 ± 0.075	0.574AspTrp: 0.574 ± 0.031	2.79AspTyr: 2.79 ± 0.066	0.0AspXaa: 0.0 ± 0.0
Glu	5.493GluAla: 5.493 ± 0.094	0.415GluCys: 0.415 ± 0.024	4.684GluAsp: 4.684 ± 0.088	6.721GluGlu: 6.721 ± 0.127	2.349GluPhe: 2.349 ± 0.062	4.402GluGly: 4.402 ± 0.074	0.975GluHis: 0.975 ± 0.04	5.51GluIle: 5.51 ± 0.08	6.532GluLys: 6.532 ± 0.125	6.037GluLeu: 6.037 ± 0.096	2.069GluMet: 2.069 ± 0.051	3.581GluAsn: 3.581 ± 0.071	1.742GluPro: 1.742 ± 0.048	1.985GluGln: 1.985 ± 0.05	3.551GluArg: 3.551 ± 0.077	3.269GluSer: 3.269 ± 0.067	3.316GluThr: 3.316 ± 0.067	4.999GluVal: 4.999 ± 0.076	0.561GluTrp: 0.561 ± 0.027	2.073GluTyr: 2.073 ± 0.058	0.0GluXaa: 0.0 ± 0.0
Phe	3.14PheAla: 3.14 ± 0.068	0.478PheCys: 0.478 ± 0.024	2.399PheAsp: 2.399 ± 0.053	2.121PheGlu: 2.121 ± 0.051	2.007PhePhe: 2.007 ± 0.056	2.905PheGly: 2.905 ± 0.065	0.794PheHis: 0.794 ± 0.03	3.186PheIle: 3.186 ± 0.074	2.332PheLys: 2.332 ± 0.06	4.155PheLeu: 4.155 ± 0.08	1.05PheMet: 1.05 ± 0.039	1.586PheAsn: 1.586 ± 0.041	1.35PhePro: 1.35 ± 0.045	1.392PheGln: 1.392 ± 0.038	1.599PheArg: 1.599 ± 0.04	2.825PheSer: 2.825 ± 0.069	2.32PheThr: 2.32 ± 0.046	2.714PheVal: 2.714 ± 0.055	0.389PheTrp: 0.389 ± 0.022	1.669PheTyr: 1.669 ± 0.045	0.0PheXaa: 0.0 ± 0.0
Gly	5.567GlyAla: 5.567 ± 0.113	0.733GlyCys: 0.733 ± 0.032	3.865GlyAsp: 3.865 ± 0.066	4.363GlyGlu: 4.363 ± 0.079	2.895GlyPhe: 2.895 ± 0.06	4.918GlyGly: 4.918 ± 0.103	1.472GlyHis: 1.472 ± 0.044	5.564GlyIle: 5.564 ± 0.089	5.31GlyLys: 5.31 ± 0.079	7.506GlyLeu: 7.506 ± 0.1	2.005GlyMet: 2.005 ± 0.052	2.527GlyAsn: 2.527 ± 0.057	1.985GlyPro: 1.985 ± 0.048	2.933GlyGln: 2.933 ± 0.065	3.457GlyArg: 3.457 ± 0.073	3.888GlySer: 3.888 ± 0.065	3.779GlyThr: 3.779 ± 0.087	5.122GlyVal: 5.122 ± 0.081	0.588GlyTrp: 0.588 ± 0.025	2.907GlyTyr: 2.907 ± 0.067	0.0GlyXaa: 0.0 ± 0.0
His	1.35HisAla: 1.35 ± 0.039	0.233HisCys: 0.233 ± 0.017	0.98HisAsp: 0.98 ± 0.039	1.153HisGlu: 1.153 ± 0.038	0.873HisPhe: 0.873 ± 0.034	1.378HisGly: 1.378 ± 0.042	0.478HisHis: 0.478 ± 0.031	1.32HisIle: 1.32 ± 0.042	1.067HisLys: 1.067 ± 0.04	1.929HisLeu: 1.929 ± 0.053	0.465HisMet: 0.465 ± 0.023	0.612HisAsn: 0.612 ± 0.027	1.008HisPro: 1.008 ± 0.031	0.637HisGln: 0.637 ± 0.026	1.045HisArg: 1.045 ± 0.038	0.941HisSer: 0.941 ± 0.035	0.932HisThr: 0.932 ± 0.035	1.241HisVal: 1.241 ± 0.042	0.242HisTrp: 0.242 ± 0.016	0.809HisTyr: 0.809 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	5.623IleAla: 5.623 ± 0.098	0.745IleCys: 0.745 ± 0.029	4.29IleAsp: 4.29 ± 0.083	4.521IleGlu: 4.521 ± 0.079	3.048IlePhe: 3.048 ± 0.071	5.158IleGly: 5.158 ± 0.082	1.503IleHis: 1.503 ± 0.041	4.734IleIle: 4.734 ± 0.097	4.111IleLys: 4.111 ± 0.089	7.677IleLeu: 7.677 ± 0.112	1.586IleMet: 1.586 ± 0.044	2.762IleAsn: 2.762 ± 0.064	2.988IlePro: 2.988 ± 0.067	2.806IleGln: 2.806 ± 0.061	3.312IleArg: 3.312 ± 0.066	4.515IleSer: 4.515 ± 0.087	3.471IleThr: 3.471 ± 0.074	4.731IleVal: 4.731 ± 0.082	0.519IleTrp: 0.519 ± 0.026	2.633IleTyr: 2.633 ± 0.061	0.0IleXaa: 0.0 ± 0.0
Lys	5.154LysAla: 5.154 ± 0.087	0.356LysCys: 0.356 ± 0.025	5.18LysAsp: 5.18 ± 0.112	6.611LysGlu: 6.611 ± 0.112	1.874LysPhe: 1.874 ± 0.061	4.141LysGly: 4.141 ± 0.079	0.934LysHis: 0.934 ± 0.036	5.392LysIle: 5.392 ± 0.101	6.413LysLys: 6.413 ± 0.129	5.599LysLeu: 5.599 ± 0.093	1.998LysMet: 1.998 ± 0.053	3.767LysAsn: 3.767 ± 0.087	1.966LysPro: 1.966 ± 0.056	2.122LysGln: 2.122 ± 0.053	3.048LysArg: 3.048 ± 0.071	3.558LysSer: 3.558 ± 0.086	3.884LysThr: 3.884 ± 0.076	4.373LysVal: 4.373 ± 0.083	0.502LysTrp: 0.502 ± 0.023	2.365LysTyr: 2.365 ± 0.053	0.0LysXaa: 0.0 ± 0.0
Leu	9.848LeuAla: 9.848 ± 0.144	1.053LeuCys: 1.053 ± 0.038	6.33LeuAsp: 6.33 ± 0.097	7.02LeuGlu: 7.02 ± 0.111	4.018LeuPhe: 4.018 ± 0.09	7.496LeuGly: 7.496 ± 0.108	1.705LeuHis: 1.705 ± 0.047	6.338LeuIle: 6.338 ± 0.103	6.748LeuLys: 6.748 ± 0.104	10.062LeuLeu: 10.062 ± 0.139	2.598LeuMet: 2.598 ± 0.062	3.79LeuAsn: 3.79 ± 0.062	4.138LeuPro: 4.138 ± 0.087	3.399LeuGln: 3.399 ± 0.075	4.77LeuArg: 4.77 ± 0.08	6.384LeuSer: 6.384 ± 0.107	5.69LeuThr: 5.69 ± 0.089	7.359LeuVal: 7.359 ± 0.117	0.823LeuTrp: 0.823 ± 0.032	3.282LeuTyr: 3.282 ± 0.072	0.0LeuXaa: 0.0 ± 0.0
Met	2.449MetAla: 2.449 ± 0.059	0.171MetCys: 0.171 ± 0.014	1.897MetAsp: 1.897 ± 0.047	1.922MetGlu: 1.922 ± 0.05	0.72MetPhe: 0.72 ± 0.031	1.953MetGly: 1.953 ± 0.051	0.405MetHis: 0.405 ± 0.02	1.757MetIle: 1.757 ± 0.044	2.145MetLys: 2.145 ± 0.049	2.246MetLeu: 2.246 ± 0.049	0.774MetMet: 0.774 ± 0.031	1.227MetAsn: 1.227 ± 0.035	0.924MetPro: 0.924 ± 0.031	0.951MetGln: 0.951 ± 0.037	1.211MetArg: 1.211 ± 0.038	1.408MetSer: 1.408 ± 0.037	1.701MetThr: 1.701 ± 0.045	1.942MetVal: 1.942 ± 0.047	0.161MetTrp: 0.161 ± 0.013	0.687MetTyr: 0.687 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	2.647AsnAla: 2.647 ± 0.06	0.37AsnCys: 0.37 ± 0.023	1.892AsnAsp: 1.892 ± 0.043	2.452AsnGlu: 2.452 ± 0.056	1.772AsnPhe: 1.772 ± 0.047	2.664AsnGly: 2.664 ± 0.067	0.831AsnHis: 0.831 ± 0.033	3.121AsnIle: 3.121 ± 0.067	2.836AsnLys: 2.836 ± 0.069	4.168AsnLeu: 4.168 ± 0.069	1.052AsnMet: 1.052 ± 0.036	1.445AsnAsn: 1.445 ± 0.048	2.085AsnPro: 2.085 ± 0.051	1.585AsnGln: 1.585 ± 0.047	1.971AsnArg: 1.971 ± 0.058	1.872AsnSer: 1.872 ± 0.053	1.886AsnThr: 1.886 ± 0.045	2.432AsnVal: 2.432 ± 0.055	0.371AsnTrp: 0.371 ± 0.02	1.654AsnTyr: 1.654 ± 0.042	0.0AsnXaa: 0.0 ± 0.0
Pro	2.674ProAla: 2.674 ± 0.06	0.282ProCys: 0.282 ± 0.021	2.209ProAsp: 2.209 ± 0.049	2.865ProGlu: 2.865 ± 0.06	1.532ProPhe: 1.532 ± 0.039	2.626ProGly: 2.626 ± 0.059	0.768ProHis: 0.768 ± 0.032	2.377ProIle: 2.377 ± 0.049	2.33ProLys: 2.33 ± 0.063	3.803ProLeu: 3.803 ± 0.075	0.9ProMet: 0.9 ± 0.035	1.369ProAsn: 1.369 ± 0.043	0.939ProPro: 0.939 ± 0.042	1.765ProGln: 1.765 ± 0.044	1.436ProArg: 1.436 ± 0.04	2.072ProSer: 2.072 ± 0.05	1.851ProThr: 1.851 ± 0.054	2.701ProVal: 2.701 ± 0.064	0.337ProTrp: 0.337 ± 0.018	1.479ProTyr: 1.479 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	3.784GlnAla: 3.784 ± 0.08	0.27GlnCys: 0.27 ± 0.018	2.645GlnAsp: 2.645 ± 0.063	3.669GlnGlu: 3.669 ± 0.084	1.12GlnPhe: 1.12 ± 0.038	3.132GlnGly: 3.132 ± 0.071	0.534GlnHis: 0.534 ± 0.022	2.397GlnIle: 2.397 ± 0.057	2.772GlnLys: 2.772 ± 0.065	3.127GlnLeu: 3.127 ± 0.063	1.115GlnMet: 1.115 ± 0.036	1.442GlnAsn: 1.442 ± 0.042	1.122GlnPro: 1.122 ± 0.042	1.245GlnGln: 1.245 ± 0.048	1.908GlnArg: 1.908 ± 0.057	1.878GlnSer: 1.878 ± 0.047	1.852GlnThr: 1.852 ± 0.044	2.991GlnVal: 2.991 ± 0.067	0.4GlnTrp: 0.4 ± 0.023	1.186GlnTyr: 1.186 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	3.599ArgAla: 3.599 ± 0.074	0.396ArgCys: 0.396 ± 0.022	2.988ArgAsp: 2.988 ± 0.073	3.981ArgGlu: 3.981 ± 0.081	1.89ArgPhe: 1.89 ± 0.043	3.206ArgGly: 3.206 ± 0.061	0.88ArgHis: 0.88 ± 0.036	3.354ArgIle: 3.354 ± 0.066	3.228ArgLys: 3.228 ± 0.07	4.874ArgLeu: 4.874 ± 0.081	1.3ArgMet: 1.3 ± 0.043	1.739ArgAsn: 1.739 ± 0.049	1.836ArgPro: 1.836 ± 0.052	2.038ArgGln: 2.038 ± 0.054	2.766ArgArg: 2.766 ± 0.07	2.301ArgSer: 2.301 ± 0.058	2.191ArgThr: 2.191 ± 0.058	3.267ArgVal: 3.267 ± 0.064	0.437ArgTrp: 0.437 ± 0.023	1.829ArgTyr: 1.829 ± 0.049	0.0ArgXaa: 0.0 ± 0.0
Ser	3.496SerAla: 3.496 ± 0.059	0.474SerCys: 0.474 ± 0.024	2.607SerAsp: 2.607 ± 0.048	2.87SerGlu: 2.87 ± 0.064	2.756SerPhe: 2.756 ± 0.065	4.229SerGly: 4.229 ± 0.073	1.094SerHis: 1.094 ± 0.038	4.067SerIle: 4.067 ± 0.084	3.558SerLys: 3.558 ± 0.094	6.464SerLeu: 6.464 ± 0.098	1.483SerMet: 1.483 ± 0.044	2.069SerAsn: 2.069 ± 0.055	2.01SerPro: 2.01 ± 0.048	2.313SerGln: 2.313 ± 0.057	2.581SerArg: 2.581 ± 0.061	3.158SerSer: 3.158 ± 0.08	2.456SerThr: 2.456 ± 0.058	3.494SerVal: 3.494 ± 0.068	0.525SerTrp: 0.525 ± 0.025	2.432SerTyr: 2.432 ± 0.063	0.0SerXaa: 0.0 ± 0.0
Thr	4.099ThrAla: 4.099 ± 0.094	0.501ThrCys: 0.501 ± 0.024	2.968ThrAsp: 2.968 ± 0.064	3.179ThrGlu: 3.179 ± 0.071	2.06ThrPhe: 2.06 ± 0.049	4.137ThrGly: 4.137 ± 0.085	0.967ThrHis: 0.967 ± 0.034	3.725ThrIle: 3.725 ± 0.066	3.107ThrLys: 3.107 ± 0.069	5.199ThrLeu: 5.199 ± 0.082	1.383ThrMet: 1.383 ± 0.041	1.828ThrAsn: 1.828 ± 0.052	2.371ThrPro: 2.371 ± 0.053	1.644ThrGln: 1.644 ± 0.045	2.235ThrArg: 2.235 ± 0.048	2.812ThrSer: 2.812 ± 0.058	2.676ThrThr: 2.676 ± 0.064	3.803ThrVal: 3.803 ± 0.081	0.471ThrTrp: 0.471 ± 0.026	1.834ThrTyr: 1.834 ± 0.053	0.0ThrXaa: 0.0 ± 0.0
Val	5.552ValAla: 5.552 ± 0.103	0.708ValCys: 0.708 ± 0.029	4.292ValAsp: 4.292 ± 0.072	4.555ValGlu: 4.555 ± 0.083	2.956ValPhe: 2.956 ± 0.059	4.732ValGly: 4.732 ± 0.098	1.296ValHis: 1.296 ± 0.039	4.566ValIle: 4.566 ± 0.074	4.304ValLys: 4.304 ± 0.082	7.292ValLeu: 7.292 ± 0.101	1.705ValMet: 1.705 ± 0.05	2.608ValAsn: 2.608 ± 0.053	2.625ValPro: 2.625 ± 0.061	2.399ValGln: 2.399 ± 0.063	3.168ValArg: 3.168 ± 0.064	3.782ValSer: 3.782 ± 0.072	3.96ValThr: 3.96 ± 0.085	4.885ValVal: 4.885 ± 0.099	0.508ValTrp: 0.508 ± 0.022	2.58ValTyr: 2.58 ± 0.063	0.0ValXaa: 0.0 ± 0.0
Trp	0.613TrpAla: 0.613 ± 0.029	0.081TrpCys: 0.081 ± 0.01	0.489TrpAsp: 0.489 ± 0.023	0.582TrpGlu: 0.582 ± 0.028	0.315TrpPhe: 0.315 ± 0.02	0.565TrpGly: 0.565 ± 0.029	0.177TrpHis: 0.177 ± 0.015	0.565TrpIle: 0.565 ± 0.028	0.523TrpLys: 0.523 ± 0.026	0.932TrpLeu: 0.932 ± 0.038	0.236TrpMet: 0.236 ± 0.018	0.381TrpAsn: 0.381 ± 0.024	0.292TrpPro: 0.292 ± 0.019	0.541TrpGln: 0.541 ± 0.029	0.495TrpArg: 0.495 ± 0.025	0.452TrpSer: 0.452 ± 0.024	0.472TrpThr: 0.472 ± 0.025	0.513TrpVal: 0.513 ± 0.026	0.134TrpTrp: 0.134 ± 0.015	0.272TrpTyr: 0.272 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.531TyrAla: 2.531 ± 0.061	0.449TyrCys: 0.449 ± 0.023	2.226TyrAsp: 2.226 ± 0.054	2.377TyrGlu: 2.377 ± 0.06	1.813TyrPhe: 1.813 ± 0.055	2.769TyrGly: 2.769 ± 0.061	0.817TyrHis: 0.817 ± 0.031	2.497TyrIle: 2.497 ± 0.05	2.265TyrLys: 2.265 ± 0.07	4.09TyrLeu: 4.09 ± 0.079	0.841TyrMet: 0.841 ± 0.03	1.389TyrAsn: 1.389 ± 0.047	1.487TyrPro: 1.487 ± 0.044	1.708TyrGln: 1.708 ± 0.047	2.109TyrArg: 2.109 ± 0.052	1.962TyrSer: 1.962 ± 0.046	1.843TyrThr: 1.843 ± 0.048	2.188TyrVal: 2.188 ± 0.057	0.359TyrTrp: 0.359 ± 0.024	1.548TyrTyr: 1.548 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2755 proteins (864364 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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