Amino acid dipepetide frequency for Asaia bogorensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.021AlaAla: 14.021 ± 0.175	1.36AlaCys: 1.36 ± 0.041	5.691AlaAsp: 5.691 ± 0.073	6.306AlaGlu: 6.306 ± 0.104	3.915AlaPhe: 3.915 ± 0.072	9.76AlaGly: 9.76 ± 0.116	2.778AlaHis: 2.778 ± 0.056	5.881AlaIle: 5.881 ± 0.088	2.893AlaLys: 2.893 ± 0.056	14.786AlaLeu: 14.786 ± 0.168	3.322AlaMet: 3.322 ± 0.056	2.717AlaAsn: 2.717 ± 0.056	6.257AlaPro: 6.257 ± 0.114	4.881AlaGln: 4.881 ± 0.078	8.773AlaArg: 8.773 ± 0.104	7.514AlaSer: 7.514 ± 0.095	6.184AlaThr: 6.184 ± 0.081	7.254AlaVal: 7.254 ± 0.094	1.548AlaTrp: 1.548 ± 0.039	2.503AlaTyr: 2.503 ± 0.058	0.001AlaXaa: 0.001 ± 0.001
Cys	1.288CysAla: 1.288 ± 0.04	0.178CysCys: 0.178 ± 0.014	0.615CysAsp: 0.615 ± 0.026	0.476CysGlu: 0.476 ± 0.022	0.405CysPhe: 0.405 ± 0.019	1.05CysGly: 1.05 ± 0.032	0.296CysHis: 0.296 ± 0.019	0.431CysIle: 0.431 ± 0.018	0.204CysLys: 0.204 ± 0.013	1.129CysLeu: 1.129 ± 0.039	0.191CysMet: 0.191 ± 0.013	0.245CysAsn: 0.245 ± 0.015	0.556CysPro: 0.556 ± 0.024	0.304CysGln: 0.304 ± 0.017	0.688CysArg: 0.688 ± 0.03	0.544CysSer: 0.544 ± 0.027	0.562CysThr: 0.562 ± 0.021	0.77CysVal: 0.77 ± 0.028	0.137CysTrp: 0.137 ± 0.011	0.199CysTyr: 0.199 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	6.339AspAla: 6.339 ± 0.09	0.511AspCys: 0.511 ± 0.025	2.943AspAsp: 2.943 ± 0.064	3.057AspGlu: 3.057 ± 0.062	1.878AspPhe: 1.878 ± 0.044	4.703AspGly: 4.703 ± 0.083	1.622AspHis: 1.622 ± 0.042	3.057AspIle: 3.057 ± 0.058	1.454AspLys: 1.454 ± 0.037	5.862AspLeu: 5.862 ± 0.081	1.494AspMet: 1.494 ± 0.038	1.351AspAsn: 1.351 ± 0.042	3.294AspPro: 3.294 ± 0.055	1.9AspGln: 1.9 ± 0.041	4.302AspArg: 4.302 ± 0.081	2.553AspSer: 2.553 ± 0.053	2.909AspThr: 2.909 ± 0.052	3.706AspVal: 3.706 ± 0.068	1.02AspTrp: 1.02 ± 0.028	1.414AspTyr: 1.414 ± 0.031	0.002AspXaa: 0.002 ± 0.001
Glu	7.294GluAla: 7.294 ± 0.126	0.399GluCys: 0.399 ± 0.021	2.407GluAsp: 2.407 ± 0.058	2.698GluGlu: 2.698 ± 0.063	1.339GluPhe: 1.339 ± 0.032	4.214GluGly: 4.214 ± 0.073	1.191GluHis: 1.191 ± 0.034	3.177GluIle: 3.177 ± 0.063	2.072GluLys: 2.072 ± 0.05	4.009GluLeu: 4.009 ± 0.075	1.347GluMet: 1.347 ± 0.039	1.656GluAsn: 1.656 ± 0.043	2.22GluPro: 2.22 ± 0.049	2.217GluGln: 2.217 ± 0.057	4.369GluArg: 4.369 ± 0.075	2.56GluSer: 2.56 ± 0.05	3.794GluThr: 3.794 ± 0.07	2.762GluVal: 2.762 ± 0.063	0.639GluTrp: 0.639 ± 0.027	0.859GluTyr: 0.859 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.965PheAla: 3.965 ± 0.063	0.486PheCys: 0.486 ± 0.021	2.34PheAsp: 2.34 ± 0.054	1.735PheGlu: 1.735 ± 0.043	1.278PhePhe: 1.278 ± 0.043	3.378PheGly: 3.378 ± 0.063	0.857PheHis: 0.857 ± 0.026	1.616PheIle: 1.616 ± 0.042	0.773PheLys: 0.773 ± 0.029	3.439PheLeu: 3.439 ± 0.067	0.955PheMet: 0.955 ± 0.033	1.074PheAsn: 1.074 ± 0.035	1.557PhePro: 1.557 ± 0.037	0.955PheGln: 0.955 ± 0.031	2.229PheArg: 2.229 ± 0.041	2.451PheSer: 2.451 ± 0.044	2.009PheThr: 2.009 ± 0.044	2.43PheVal: 2.43 ± 0.047	0.528PheTrp: 0.528 ± 0.022	0.899PheTyr: 0.899 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	9.111GlyAla: 9.111 ± 0.112	0.997GlyCys: 0.997 ± 0.034	3.996GlyAsp: 3.996 ± 0.068	4.138GlyGlu: 4.138 ± 0.071	3.578GlyPhe: 3.578 ± 0.065	7.208GlyGly: 7.208 ± 0.117	2.262GlyHis: 2.262 ± 0.051	4.437GlyIle: 4.437 ± 0.067	2.999GlyLys: 2.999 ± 0.059	9.02GlyLeu: 9.02 ± 0.106	2.508GlyMet: 2.508 ± 0.051	2.27GlyAsn: 2.27 ± 0.064	3.352GlyPro: 3.352 ± 0.058	3.352GlyGln: 3.352 ± 0.056	5.95GlyArg: 5.95 ± 0.08	4.953GlySer: 4.953 ± 0.08	4.921GlyThr: 4.921 ± 0.076	5.965GlyVal: 5.965 ± 0.091	1.48GlyTrp: 1.48 ± 0.046	2.302GlyTyr: 2.302 ± 0.055	0.002GlyXaa: 0.002 ± 0.001
His	2.889HisAla: 2.889 ± 0.055	0.269HisCys: 0.269 ± 0.019	1.761HisAsp: 1.761 ± 0.043	1.381HisGlu: 1.381 ± 0.037	1.028HisPhe: 1.028 ± 0.031	2.323HisGly: 2.323 ± 0.053	0.875HisHis: 0.875 ± 0.032	1.177HisIle: 1.177 ± 0.039	0.569HisLys: 0.569 ± 0.024	2.41HisLeu: 2.41 ± 0.057	0.564HisMet: 0.564 ± 0.024	0.603HisAsn: 0.603 ± 0.026	1.557HisPro: 1.557 ± 0.041	0.779HisGln: 0.779 ± 0.028	1.719HisArg: 1.719 ± 0.05	1.188HisSer: 1.188 ± 0.033	0.961HisThr: 0.961 ± 0.034	1.787HisVal: 1.787 ± 0.045	0.414HisTrp: 0.414 ± 0.019	0.684HisTyr: 0.684 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.807IleAla: 6.807 ± 0.078	0.614IleCys: 0.614 ± 0.024	3.484IleAsp: 3.484 ± 0.06	3.221IleGlu: 3.221 ± 0.051	1.498IlePhe: 1.498 ± 0.04	4.943IleGly: 4.943 ± 0.075	1.0IleHis: 1.0 ± 0.028	2.351IleIle: 2.351 ± 0.056	1.187IleLys: 1.187 ± 0.035	4.69IleLeu: 4.69 ± 0.082	1.216IleMet: 1.216 ± 0.034	1.474IleAsn: 1.474 ± 0.047	2.546IlePro: 2.546 ± 0.047	1.322IleGln: 1.322 ± 0.036	3.492IleArg: 3.492 ± 0.057	3.005IleSer: 3.005 ± 0.058	2.975IleThr: 2.975 ± 0.06	3.91IleVal: 3.91 ± 0.061	0.628IleTrp: 0.628 ± 0.026	1.017IleTyr: 1.017 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	3.893LysAla: 3.893 ± 0.065	0.134LysCys: 0.134 ± 0.011	1.377LysAsp: 1.377 ± 0.039	1.218LysGlu: 1.218 ± 0.041	0.709LysPhe: 0.709 ± 0.028	2.45LysGly: 2.45 ± 0.051	0.518LysHis: 0.518 ± 0.022	1.485LysIle: 1.485 ± 0.047	0.984LysLys: 0.984 ± 0.034	2.767LysLeu: 2.767 ± 0.063	0.639LysMet: 0.639 ± 0.028	0.795LysAsn: 0.795 ± 0.028	1.851LysPro: 1.851 ± 0.043	1.021LysGln: 1.021 ± 0.034	2.074LysArg: 2.074 ± 0.05	1.599LysSer: 1.599 ± 0.044	1.799LysThr: 1.799 ± 0.044	1.606LysVal: 1.606 ± 0.043	0.294LysTrp: 0.294 ± 0.02	0.455LysTyr: 0.455 ± 0.022	0.001LysXaa: 0.001 ± 0.001
Leu	12.87LeuAla: 12.87 ± 0.133	1.289LeuCys: 1.289 ± 0.036	6.292LeuAsp: 6.292 ± 0.098	4.796LeuGlu: 4.796 ± 0.072	3.581LeuPhe: 3.581 ± 0.076	8.343LeuGly: 8.343 ± 0.103	2.583LeuHis: 2.583 ± 0.058	5.035LeuIle: 5.035 ± 0.08	2.799LeuLys: 2.799 ± 0.061	9.745LeuLeu: 9.745 ± 0.121	2.444LeuMet: 2.444 ± 0.052	2.799LeuAsn: 2.799 ± 0.051	6.508LeuPro: 6.508 ± 0.084	3.117LeuGln: 3.117 ± 0.061	7.797LeuArg: 7.797 ± 0.105	7.622LeuSer: 7.622 ± 0.087	6.294LeuThr: 6.294 ± 0.084	7.139LeuVal: 7.139 ± 0.097	1.288LeuTrp: 1.288 ± 0.037	2.252LeuTyr: 2.252 ± 0.043	0.002LeuXaa: 0.002 ± 0.001
Met	3.202MetAla: 3.202 ± 0.066	0.151MetCys: 0.151 ± 0.011	1.099MetAsp: 1.099 ± 0.035	1.055MetGlu: 1.055 ± 0.035	0.655MetPhe: 0.655 ± 0.025	1.917MetGly: 1.917 ± 0.044	0.496MetHis: 0.496 ± 0.021	1.513MetIle: 1.513 ± 0.039	0.879MetLys: 0.879 ± 0.033	2.597MetLeu: 2.597 ± 0.053	0.689MetMet: 0.689 ± 0.027	0.706MetAsn: 0.706 ± 0.026	1.672MetPro: 1.672 ± 0.043	0.997MetGln: 0.997 ± 0.032	1.926MetArg: 1.926 ± 0.049	1.886MetSer: 1.886 ± 0.049	2.136MetThr: 2.136 ± 0.047	1.64MetVal: 1.64 ± 0.045	0.191MetTrp: 0.191 ± 0.013	0.276MetTyr: 0.276 ± 0.017	0.001MetXaa: 0.001 ± 0.001
Asn	3.308AsnAla: 3.308 ± 0.055	0.238AsnCys: 0.238 ± 0.015	1.521AsnAsp: 1.521 ± 0.043	1.258AsnGlu: 1.258 ± 0.039	0.974AsnPhe: 0.974 ± 0.04	2.602AsnGly: 2.602 ± 0.063	0.578AsnHis: 0.578 ± 0.024	1.386AsnIle: 1.386 ± 0.039	0.669AsnLys: 0.669 ± 0.029	2.544AsnLeu: 2.544 ± 0.054	0.661AsnMet: 0.661 ± 0.025	0.856AsnAsn: 0.856 ± 0.037	1.831AsnPro: 1.831 ± 0.049	0.922AsnGln: 0.922 ± 0.036	1.84AsnArg: 1.84 ± 0.044	1.293AsnSer: 1.293 ± 0.043	1.485AsnThr: 1.485 ± 0.046	1.813AsnVal: 1.813 ± 0.049	0.468AsnTrp: 0.468 ± 0.022	0.721AsnTyr: 0.721 ± 0.035	0.0AsnXaa: 0.0 ± 0.0
Pro	6.438ProAla: 6.438 ± 0.102	0.503ProCys: 0.503 ± 0.021	4.043ProAsp: 4.043 ± 0.065	3.697ProGlu: 3.697 ± 0.059	1.956ProPhe: 1.956 ± 0.045	4.828ProGly: 4.828 ± 0.082	1.404ProHis: 1.404 ± 0.035	2.185ProIle: 2.185 ± 0.044	1.37ProLys: 1.37 ± 0.038	5.099ProLeu: 5.099 ± 0.078	1.294ProMet: 1.294 ± 0.036	1.341ProAsn: 1.341 ± 0.036	2.835ProPro: 2.835 ± 0.078	1.927ProGln: 1.927 ± 0.046	2.989ProArg: 2.989 ± 0.062	3.372ProSer: 3.372 ± 0.055	2.648ProThr: 2.648 ± 0.06	4.632ProVal: 4.632 ± 0.066	0.692ProTrp: 0.692 ± 0.026	1.244ProTyr: 1.244 ± 0.037	0.001ProXaa: 0.001 ± 0.001
Gln	4.873GlnAla: 4.873 ± 0.083	0.27GlnCys: 0.27 ± 0.015	2.024GlnAsp: 2.024 ± 0.042	1.74GlnGlu: 1.74 ± 0.047	1.174GlnPhe: 1.174 ± 0.033	3.003GlnGly: 3.003 ± 0.062	0.813GlnHis: 0.813 ± 0.032	2.341GlnIle: 2.341 ± 0.047	1.229GlnLys: 1.229 ± 0.041	2.812GlnLeu: 2.812 ± 0.055	0.828GlnMet: 0.828 ± 0.027	1.17GlnAsn: 1.17 ± 0.04	1.898GlnPro: 1.898 ± 0.037	1.338GlnGln: 1.338 ± 0.042	2.51GlnArg: 2.51 ± 0.048	2.268GlnSer: 2.268 ± 0.052	2.211GlnThr: 2.211 ± 0.052	2.21GlnVal: 2.21 ± 0.05	0.469GlnTrp: 0.469 ± 0.023	0.761GlnTyr: 0.761 ± 0.03	0.001GlnXaa: 0.001 ± 0.001
Arg	7.658ArgAla: 7.658 ± 0.11	0.617ArgCys: 0.617 ± 0.028	4.287ArgAsp: 4.287 ± 0.07	4.037ArgGlu: 4.037 ± 0.076	2.93ArgPhe: 2.93 ± 0.055	4.599ArgGly: 4.599 ± 0.066	2.225ArgHis: 2.225 ± 0.054	3.944ArgIle: 3.944 ± 0.064	2.189ArgLys: 2.189 ± 0.05	8.567ArgLeu: 8.567 ± 0.11	1.894ArgMet: 1.894 ± 0.042	2.037ArgAsn: 2.037 ± 0.044	3.667ArgPro: 3.667 ± 0.055	3.015ArgGln: 3.015 ± 0.061	5.652ArgArg: 5.652 ± 0.096	3.946ArgSer: 3.946 ± 0.064	3.246ArgThr: 3.246 ± 0.065	4.5ArgVal: 4.5 ± 0.065	1.041ArgTrp: 1.041 ± 0.034	1.989ArgTyr: 1.989 ± 0.048	0.001ArgXaa: 0.001 ± 0.001
Ser	6.817SerAla: 6.817 ± 0.097	0.659SerCys: 0.659 ± 0.027	3.188SerAsp: 3.188 ± 0.055	2.807SerGlu: 2.807 ± 0.061	2.435SerPhe: 2.435 ± 0.046	6.006SerGly: 6.006 ± 0.092	1.503SerHis: 1.503 ± 0.036	2.831SerIle: 2.831 ± 0.059	1.356SerLys: 1.356 ± 0.035	6.743SerLeu: 6.743 ± 0.093	1.511SerMet: 1.511 ± 0.042	1.514SerAsn: 1.514 ± 0.046	3.403SerPro: 3.403 ± 0.062	1.974SerGln: 1.974 ± 0.041	4.212SerArg: 4.212 ± 0.066	3.68SerSer: 3.68 ± 0.087	3.143SerThr: 3.143 ± 0.07	4.255SerVal: 4.255 ± 0.067	0.938SerTrp: 0.938 ± 0.031	1.462SerTyr: 1.462 ± 0.043	0.003SerXaa: 0.003 ± 0.002
Thr	6.058ThrAla: 6.058 ± 0.078	0.507ThrCys: 0.507 ± 0.022	2.913ThrAsp: 2.913 ± 0.054	2.496ThrGlu: 2.496 ± 0.059	1.623ThrPhe: 1.623 ± 0.045	5.53ThrGly: 5.53 ± 0.085	1.387ThrHis: 1.387 ± 0.034	3.141ThrIle: 3.141 ± 0.056	1.303ThrLys: 1.303 ± 0.041	7.17ThrLeu: 7.17 ± 0.094	1.319ThrMet: 1.319 ± 0.039	1.453ThrAsn: 1.453 ± 0.044	3.994ThrPro: 3.994 ± 0.067	2.021ThrGln: 2.021 ± 0.053	3.973ThrArg: 3.973 ± 0.064	3.2ThrSer: 3.2 ± 0.072	3.148ThrThr: 3.148 ± 0.067	3.85ThrVal: 3.85 ± 0.072	0.621ThrTrp: 0.621 ± 0.023	1.217ThrTyr: 1.217 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	7.811ValAla: 7.811 ± 0.106	0.649ValCys: 0.649 ± 0.025	3.284ValAsp: 3.284 ± 0.058	3.454ValGlu: 3.454 ± 0.06	2.653ValPhe: 2.653 ± 0.057	4.724ValGly: 4.724 ± 0.079	1.487ValHis: 1.487 ± 0.045	3.826ValIle: 3.826 ± 0.06	1.767ValLys: 1.767 ± 0.043	7.193ValLeu: 7.193 ± 0.102	2.022ValMet: 2.022 ± 0.048	1.781ValAsn: 1.781 ± 0.052	3.662ValPro: 3.662 ± 0.061	2.359ValGln: 2.359 ± 0.052	4.291ValArg: 4.291 ± 0.064	4.742ValSer: 4.742 ± 0.067	4.572ValThr: 4.572 ± 0.08	4.935ValVal: 4.935 ± 0.09	0.868ValTrp: 0.868 ± 0.029	1.354ValTyr: 1.354 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.204TrpAla: 1.204 ± 0.031	0.174TrpCys: 0.174 ± 0.013	0.629TrpAsp: 0.629 ± 0.025	0.514TrpGlu: 0.514 ± 0.021	0.551TrpPhe: 0.551 ± 0.023	0.985TrpGly: 0.985 ± 0.034	0.455TrpHis: 0.455 ± 0.024	0.65TrpIle: 0.65 ± 0.026	0.457TrpLys: 0.457 ± 0.024	1.745TrpLeu: 1.745 ± 0.043	0.382TrpMet: 0.382 ± 0.02	0.459TrpAsn: 0.459 ± 0.022	0.679TrpPro: 0.679 ± 0.025	0.662TrpGln: 0.662 ± 0.027	1.285TrpArg: 1.285 ± 0.036	0.945TrpSer: 0.945 ± 0.031	0.731TrpThr: 0.731 ± 0.027	0.803TrpVal: 0.803 ± 0.025	0.223TrpTrp: 0.223 ± 0.018	0.303TrpTyr: 0.303 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.494TyrAla: 2.494 ± 0.057	0.268TyrCys: 0.268 ± 0.018	1.476TyrAsp: 1.476 ± 0.041	1.138TyrGlu: 1.138 ± 0.032	0.794TyrPhe: 0.794 ± 0.032	2.235TyrGly: 2.235 ± 0.06	0.608TyrHis: 0.608 ± 0.028	0.916TyrIle: 0.916 ± 0.034	0.515TyrLys: 0.515 ± 0.023	2.268TyrLeu: 2.268 ± 0.046	0.402TyrMet: 0.402 ± 0.023	0.666TyrAsn: 0.666 ± 0.033	1.157TyrPro: 1.157 ± 0.035	0.876TyrGln: 0.876 ± 0.036	1.965TyrArg: 1.965 ± 0.044	1.12TyrSer: 1.12 ± 0.042	1.197TyrThr: 1.197 ± 0.042	1.469TyrVal: 1.469 ± 0.036	0.347TyrTrp: 0.347 ± 0.022	0.635TyrTyr: 0.635 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.003XaaAla: 0.003 ± 0.002	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.001	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.001	0.0XaaLeu: 0.0 ± 0.0	0.001XaaMet: 0.001 ± 0.001	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.002XaaGln: 0.002 ± 0.001	0.003XaaArg: 0.003 ± 0.002	0.0XaaSer: 0.0 ± 0.0	0.001XaaThr: 0.001 ± 0.001	0.0XaaVal: 0.0 ± 0.0	0.002XaaTrp: 0.002 ± 0.002	0.0XaaTyr: 0.0 ± 0.0	0.131XaaXaa: 0.131 ± 0.114

Statistics based on 3273 proteins (1008756 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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