Amino acid dipepetide frequency for Sanxia tombus-like virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.138AlaAla: 4.138 ± 2.586
1.379AlaCys: 1.379 ± 0.705
4.138AlaAsp: 4.138 ± 0.235
2.759AlaGlu: 2.759 ± 1.41
1.379AlaPhe: 1.379 ± 0.705
4.138AlaGly: 4.138 ± 2.586
0.0AlaHis: 0.0 ± 0.0
1.379AlaIle: 1.379 ± 1.646
1.379AlaLys: 1.379 ± 0.705
4.138AlaLeu: 4.138 ± 0.235
1.379AlaMet: 1.379 ± 0.705
5.517AlaAsn: 5.517 ± 4.231
4.138AlaPro: 4.138 ± 0.235
4.138AlaGln: 4.138 ± 0.235
9.655AlaArg: 9.655 ± 4.467
1.379AlaSer: 1.379 ± 0.705
2.759AlaThr: 2.759 ± 3.291
6.897AlaVal: 6.897 ± 1.175
2.759AlaTrp: 2.759 ± 0.94
2.759AlaTyr: 2.759 ± 1.41
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.379CysAsp: 1.379 ± 0.705
0.0CysGlu: 0.0 ± 0.0
2.759CysPhe: 2.759 ± 3.291
2.759CysGly: 2.759 ± 1.41
0.0CysHis: 0.0 ± 0.0
1.379CysIle: 1.379 ± 0.705
2.759CysLys: 2.759 ± 1.41
4.138CysLeu: 4.138 ± 2.116
1.379CysMet: 1.379 ± 0.705
1.379CysAsn: 1.379 ± 0.705
1.379CysPro: 1.379 ± 0.705
2.759CysGln: 2.759 ± 0.94
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.379CysThr: 1.379 ± 0.705
2.759CysVal: 2.759 ± 0.94
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.138AspAla: 4.138 ± 2.116
2.759AspCys: 2.759 ± 1.41
2.759AspAsp: 2.759 ± 1.41
1.379AspGlu: 1.379 ± 0.705
2.759AspPhe: 2.759 ± 1.41
2.759AspGly: 2.759 ± 1.41
1.379AspHis: 1.379 ± 1.646
4.138AspIle: 4.138 ± 2.586
2.759AspLys: 2.759 ± 1.41
1.379AspLeu: 1.379 ± 1.646
1.379AspMet: 1.379 ± 0.705
2.759AspAsn: 2.759 ± 1.41
1.379AspPro: 1.379 ± 0.705
1.379AspGln: 1.379 ± 0.705
2.759AspArg: 2.759 ± 1.41
4.138AspSer: 4.138 ± 2.586
2.759AspThr: 2.759 ± 1.41
4.138AspVal: 4.138 ± 2.116
1.379AspTrp: 1.379 ± 1.646
2.759AspTyr: 2.759 ± 1.41
0.0AspXaa: 0.0 ± 0.0
Glu
1.379GluAla: 1.379 ± 0.705
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
0.0GluGlu: 0.0 ± 0.0
4.138GluPhe: 4.138 ± 0.235
5.517GluGly: 5.517 ± 1.881
2.759GluHis: 2.759 ± 1.41
2.759GluIle: 2.759 ± 1.41
1.379GluLys: 1.379 ± 0.705
4.138GluLeu: 4.138 ± 2.116
2.759GluMet: 2.759 ± 3.291
2.759GluAsn: 2.759 ± 3.291
0.0GluPro: 0.0 ± 0.0
2.759GluGln: 2.759 ± 1.41
2.759GluArg: 2.759 ± 1.41
1.379GluSer: 1.379 ± 0.705
2.759GluThr: 2.759 ± 0.94
2.759GluVal: 2.759 ± 1.41
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
5.517PheAla: 5.517 ± 1.881
1.379PheCys: 1.379 ± 0.705
2.759PheAsp: 2.759 ± 1.41
5.517PheGlu: 5.517 ± 0.47
0.0PhePhe: 0.0 ± 0.0
4.138PheGly: 4.138 ± 2.116
0.0PheHis: 0.0 ± 0.0
2.759PheIle: 2.759 ± 1.41
2.759PheLys: 2.759 ± 1.41
2.759PheLeu: 2.759 ± 1.41
0.0PheMet: 0.0 ± 0.0
1.379PheAsn: 1.379 ± 0.705
1.379PhePro: 1.379 ± 1.646
2.759PheGln: 2.759 ± 0.94
4.138PheArg: 4.138 ± 0.235
1.379PheSer: 1.379 ± 1.646
2.759PheThr: 2.759 ± 1.41
2.759PheVal: 2.759 ± 1.41
1.379PheTrp: 1.379 ± 0.705
2.759PheTyr: 2.759 ± 1.41
0.0PheXaa: 0.0 ± 0.0
Gly
0.0GlyAla: 0.0 ± 0.0
0.0GlyCys: 0.0 ± 0.0
5.517GlyAsp: 5.517 ± 2.821
1.379GlyGlu: 1.379 ± 0.705
1.379GlyPhe: 1.379 ± 0.705
4.138GlyGly: 4.138 ± 0.235
4.138GlyHis: 4.138 ± 2.116
9.655GlyIle: 9.655 ± 2.586
4.138GlyLys: 4.138 ± 0.235
9.655GlyLeu: 9.655 ± 4.467
0.0GlyMet: 0.0 ± 0.0
5.517GlyAsn: 5.517 ± 1.881
0.0GlyPro: 0.0 ± 0.0
1.379GlyGln: 1.379 ± 0.705
4.138GlyArg: 4.138 ± 0.235
4.138GlySer: 4.138 ± 2.116
6.897GlyThr: 6.897 ± 8.228
9.655GlyVal: 9.655 ± 0.235
0.0GlyTrp: 0.0 ± 0.0
1.379GlyTyr: 1.379 ± 1.646
0.0GlyXaa: 0.0 ± 0.0
His
1.379HisAla: 1.379 ± 0.705
0.0HisCys: 0.0 ± 0.0
5.517HisAsp: 5.517 ± 2.821
1.379HisGlu: 1.379 ± 0.705
0.0HisPhe: 0.0 ± 0.0
1.379HisGly: 1.379 ± 0.705
0.0HisHis: 0.0 ± 0.0
1.379HisIle: 1.379 ± 0.705
0.0HisLys: 0.0 ± 0.0
2.759HisLeu: 2.759 ± 1.41
0.0HisMet: 0.0 ± 0.0
4.138HisAsn: 4.138 ± 2.116
0.0HisPro: 0.0 ± 0.0
1.379HisGln: 1.379 ± 0.705
0.0HisArg: 0.0 ± 0.0
1.379HisSer: 1.379 ± 1.646
0.0HisThr: 0.0 ± 0.0
1.379HisVal: 1.379 ± 0.705
0.0HisTrp: 0.0 ± 0.0
1.379HisTyr: 1.379 ± 1.646
0.0HisXaa: 0.0 ± 0.0
Ile
5.517IleAla: 5.517 ± 1.881
1.379IleCys: 1.379 ± 0.705
5.517IleAsp: 5.517 ± 2.821
2.759IleGlu: 2.759 ± 0.94
5.517IlePhe: 5.517 ± 0.47
1.379IleGly: 1.379 ± 1.646
0.0IleHis: 0.0 ± 0.0
1.379IleIle: 1.379 ± 0.705
5.517IleLys: 5.517 ± 0.47
1.379IleLeu: 1.379 ± 1.646
1.379IleMet: 1.379 ± 0.705
2.759IleAsn: 2.759 ± 1.41
2.759IlePro: 2.759 ± 0.94
1.379IleGln: 1.379 ± 0.705
6.897IleArg: 6.897 ± 1.175
4.138IleSer: 4.138 ± 2.586
2.759IleThr: 2.759 ± 1.41
1.379IleVal: 1.379 ± 0.705
1.379IleTrp: 1.379 ± 0.705
2.759IleTyr: 2.759 ± 0.94
0.0IleXaa: 0.0 ± 0.0
Lys
5.517LysAla: 5.517 ± 0.47
4.138LysCys: 4.138 ± 0.235
0.0LysAsp: 0.0 ± 0.0
0.0LysGlu: 0.0 ± 0.0
4.138LysPhe: 4.138 ± 2.116
2.759LysGly: 2.759 ± 0.94
2.759LysHis: 2.759 ± 1.41
1.379LysIle: 1.379 ± 0.705
1.379LysLys: 1.379 ± 1.646
4.138LysLeu: 4.138 ± 2.116
2.759LysMet: 2.759 ± 0.94
2.759LysAsn: 2.759 ± 1.41
4.138LysPro: 4.138 ± 2.116
1.379LysGln: 1.379 ± 0.705
4.138LysArg: 4.138 ± 2.116
0.0LysSer: 0.0 ± 0.0
0.0LysThr: 0.0 ± 0.0
2.759LysVal: 2.759 ± 3.291
1.379LysTrp: 1.379 ± 0.705
4.138LysTyr: 4.138 ± 0.235
0.0LysXaa: 0.0 ± 0.0
Leu
5.517LeuAla: 5.517 ± 2.821
0.0LeuCys: 0.0 ± 0.0
2.759LeuAsp: 2.759 ± 1.41
11.034LeuGlu: 11.034 ± 1.41
1.379LeuPhe: 1.379 ± 1.646
6.897LeuGly: 6.897 ± 3.526
4.138LeuHis: 4.138 ± 0.235
5.517LeuIle: 5.517 ± 0.47
6.897LeuLys: 6.897 ± 1.175
2.759LeuLeu: 2.759 ± 1.41
4.138LeuMet: 4.138 ± 2.116
2.759LeuAsn: 2.759 ± 0.94
2.759LeuPro: 2.759 ± 0.94
2.759LeuGln: 2.759 ± 0.94
4.138LeuArg: 4.138 ± 0.235
5.517LeuSer: 5.517 ± 0.47
5.517LeuThr: 5.517 ± 1.881
0.0LeuVal: 0.0 ± 0.0
0.0LeuTrp: 0.0 ± 0.0
2.759LeuTyr: 2.759 ± 1.41
0.0LeuXaa: 0.0 ± 0.0
Met
1.379MetAla: 1.379 ± 1.646
2.759MetCys: 2.759 ± 1.41
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
2.759MetPhe: 2.759 ± 0.94
1.379MetGly: 1.379 ± 0.705
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
4.138MetLeu: 4.138 ± 0.235
0.0MetMet: 0.0 ± 0.0
1.379MetAsn: 1.379 ± 0.705
0.0MetPro: 0.0 ± 0.0
1.379MetGln: 1.379 ± 0.705
1.379MetArg: 1.379 ± 0.705
4.138MetSer: 4.138 ± 2.116
1.379MetThr: 1.379 ± 0.705
4.138MetVal: 4.138 ± 2.586
0.0MetTrp: 0.0 ± 0.0
2.759MetTyr: 2.759 ± 1.41
0.0MetXaa: 0.0 ± 0.0
Asn
5.517AsnAla: 5.517 ± 4.231
2.759AsnCys: 2.759 ± 1.41
0.0AsnAsp: 0.0 ± 0.0
1.379AsnGlu: 1.379 ± 1.646
1.379AsnPhe: 1.379 ± 0.705
2.759AsnGly: 2.759 ± 1.41
0.0AsnHis: 0.0 ± 0.0
2.759AsnIle: 2.759 ± 1.41
1.379AsnLys: 1.379 ± 0.705
5.517AsnLeu: 5.517 ± 0.47
1.379AsnMet: 1.379 ± 1.646
6.897AsnAsn: 6.897 ± 1.175
4.138AsnPro: 4.138 ± 2.586
1.379AsnGln: 1.379 ± 0.705
1.379AsnArg: 1.379 ± 0.705
4.138AsnSer: 4.138 ± 2.116
4.138AsnThr: 4.138 ± 2.586
5.517AsnVal: 5.517 ± 0.47
0.0AsnTrp: 0.0 ± 0.0
2.759AsnTyr: 2.759 ± 0.94
0.0AsnXaa: 0.0 ± 0.0
Pro
5.517ProAla: 5.517 ± 0.47
1.379ProCys: 1.379 ± 0.705
4.138ProAsp: 4.138 ± 2.116
1.379ProGlu: 1.379 ± 1.646
0.0ProPhe: 0.0 ± 0.0
5.517ProGly: 5.517 ± 0.47
0.0ProHis: 0.0 ± 0.0
2.759ProIle: 2.759 ± 0.94
2.759ProLys: 2.759 ± 0.94
4.138ProLeu: 4.138 ± 0.235
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
5.517ProArg: 5.517 ± 1.881
1.379ProSer: 1.379 ± 1.646
4.138ProThr: 4.138 ± 0.235
6.897ProVal: 6.897 ± 1.175
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.759GlnAla: 2.759 ± 1.41
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
1.379GlnGlu: 1.379 ± 1.646
5.517GlnPhe: 5.517 ± 2.821
1.379GlnGly: 1.379 ± 1.646
1.379GlnHis: 1.379 ± 0.705
1.379GlnIle: 1.379 ± 0.705
2.759GlnLys: 2.759 ± 0.94
2.759GlnLeu: 2.759 ± 0.94
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
5.517GlnPro: 5.517 ± 0.47
5.517GlnGln: 5.517 ± 0.47
1.379GlnArg: 1.379 ± 0.705
4.138GlnSer: 4.138 ± 2.116
4.138GlnThr: 4.138 ± 2.586
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
4.138GlnTyr: 4.138 ± 0.235
0.0GlnXaa: 0.0 ± 0.0
Arg
4.138ArgAla: 4.138 ± 2.116
4.138ArgCys: 4.138 ± 2.586
4.138ArgAsp: 4.138 ± 0.235
0.0ArgGlu: 0.0 ± 0.0
2.759ArgPhe: 2.759 ± 1.41
8.276ArgGly: 8.276 ± 2.821
1.379ArgHis: 1.379 ± 0.705
8.276ArgIle: 8.276 ± 5.172
2.759ArgLys: 2.759 ± 1.41
4.138ArgLeu: 4.138 ± 2.116
4.138ArgMet: 4.138 ± 2.116
2.759ArgAsn: 2.759 ± 0.94
5.517ArgPro: 5.517 ± 0.47
4.138ArgGln: 4.138 ± 0.235
4.138ArgArg: 4.138 ± 2.116
2.759ArgSer: 2.759 ± 0.94
8.276ArgThr: 8.276 ± 1.881
4.138ArgVal: 4.138 ± 2.116
0.0ArgTrp: 0.0 ± 0.0
1.379ArgTyr: 1.379 ± 0.705
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
0.0SerCys: 0.0 ± 0.0
1.379SerAsp: 1.379 ± 1.646
1.379SerGlu: 1.379 ± 0.705
2.759SerPhe: 2.759 ± 1.41
5.517SerGly: 5.517 ± 1.881
1.379SerHis: 1.379 ± 0.705
0.0SerIle: 0.0 ± 0.0
2.759SerLys: 2.759 ± 1.41
4.138SerLeu: 4.138 ± 0.235
1.379SerMet: 1.379 ± 0.47
2.759SerAsn: 2.759 ± 3.291
4.138SerPro: 4.138 ± 2.116
1.379SerGln: 1.379 ± 0.705
12.414SerArg: 12.414 ± 1.646
0.0SerSer: 0.0 ± 0.0
4.138SerThr: 4.138 ± 2.586
6.897SerVal: 6.897 ± 3.526
0.0SerTrp: 0.0 ± 0.0
1.379SerTyr: 1.379 ± 0.705
0.0SerXaa: 0.0 ± 0.0
Thr
5.517ThrAla: 5.517 ± 4.231
2.759ThrCys: 2.759 ± 0.94
4.138ThrAsp: 4.138 ± 2.586
1.379ThrGlu: 1.379 ± 0.705
1.379ThrPhe: 1.379 ± 0.705
1.379ThrGly: 1.379 ± 0.705
2.759ThrHis: 2.759 ± 1.41
5.517ThrIle: 5.517 ± 1.881
4.138ThrLys: 4.138 ± 2.116
2.759ThrLeu: 2.759 ± 0.94
2.759ThrMet: 2.759 ± 1.41
4.138ThrAsn: 4.138 ± 0.235
2.759ThrPro: 2.759 ± 0.94
1.379ThrGln: 1.379 ± 1.646
2.759ThrArg: 2.759 ± 0.94
4.138ThrSer: 4.138 ± 2.586
0.0ThrThr: 0.0 ± 0.0
6.897ThrVal: 6.897 ± 5.877
1.379ThrTrp: 1.379 ± 0.705
1.379ThrTyr: 1.379 ± 0.705
0.0ThrXaa: 0.0 ± 0.0
Val
6.897ValAla: 6.897 ± 8.228
1.379ValCys: 1.379 ± 0.705
4.138ValAsp: 4.138 ± 0.235
5.517ValGlu: 5.517 ± 2.821
2.759ValPhe: 2.759 ± 1.41
6.897ValGly: 6.897 ± 1.175
0.0ValHis: 0.0 ± 0.0
2.759ValIle: 2.759 ± 0.94
2.759ValLys: 2.759 ± 0.94
6.897ValLeu: 6.897 ± 3.526
0.0ValMet: 0.0 ± 0.0
2.759ValAsn: 2.759 ± 1.41
2.759ValPro: 2.759 ± 0.94
0.0ValGln: 0.0 ± 0.0
2.759ValArg: 2.759 ± 0.94
6.897ValSer: 6.897 ± 1.175
4.138ValThr: 4.138 ± 0.235
0.0ValVal: 0.0 ± 0.0
2.759ValTrp: 2.759 ± 0.94
6.897ValTyr: 6.897 ± 3.526
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.379TrpAsp: 1.379 ± 1.646
0.0TrpGlu: 0.0 ± 0.0
1.379TrpPhe: 1.379 ± 1.646
1.379TrpGly: 1.379 ± 0.705
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.379TrpLeu: 1.379 ± 0.705
1.379TrpMet: 1.379 ± 0.705
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
4.138TrpGln: 4.138 ± 0.235
1.379TrpArg: 1.379 ± 0.705
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.379TyrAla: 1.379 ± 1.646
0.0TyrCys: 0.0 ± 0.0
1.379TyrAsp: 1.379 ± 0.705
1.379TyrGlu: 1.379 ± 0.705
4.138TyrPhe: 4.138 ± 2.116
2.759TyrGly: 2.759 ± 1.41
1.379TyrHis: 1.379 ± 0.705
2.759TyrIle: 2.759 ± 1.41
1.379TyrLys: 1.379 ± 1.646
4.138TyrLeu: 4.138 ± 0.235
1.379TyrMet: 1.379 ± 0.705
2.759TyrAsn: 2.759 ± 1.41
2.759TyrPro: 2.759 ± 0.94
2.759TyrGln: 2.759 ± 0.94
5.517TyrArg: 5.517 ± 2.821
4.138TyrSer: 4.138 ± 0.235
1.379TyrThr: 1.379 ± 0.705
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (726 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski