Amino acid dipepetide frequency for Gymnopus luxurians FD-317 M1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.966AlaAla: 6.966 ± 0.053	1.056AlaCys: 1.056 ± 0.016	3.481AlaAsp: 3.481 ± 0.028	4.302AlaGlu: 4.302 ± 0.032	3.401AlaPhe: 3.401 ± 0.032	4.922AlaGly: 4.922 ± 0.041	1.761AlaHis: 1.761 ± 0.016	4.093AlaIle: 4.093 ± 0.03	3.43AlaLys: 3.43 ± 0.032	7.769AlaLeu: 7.769 ± 0.041	1.692AlaMet: 1.692 ± 0.019	2.808AlaAsn: 2.808 ± 0.026	4.149AlaPro: 4.149 ± 0.034	3.208AlaGln: 3.208 ± 0.031	3.936AlaArg: 3.936 ± 0.032	7.147AlaSer: 7.147 ± 0.05	4.54AlaThr: 4.54 ± 0.034	4.827AlaVal: 4.827 ± 0.031	1.077AlaTrp: 1.077 ± 0.015	2.1AlaTyr: 2.1 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.939CysAla: 0.939 ± 0.014	0.308CysCys: 0.308 ± 0.008	0.657CysAsp: 0.657 ± 0.013	0.635CysGlu: 0.635 ± 0.013	0.624CysPhe: 0.624 ± 0.013	0.913CysGly: 0.913 ± 0.014	0.406CysHis: 0.406 ± 0.01	0.904CysIle: 0.904 ± 0.015	0.611CysLys: 0.611 ± 0.012	1.517CysLeu: 1.517 ± 0.019	0.305CysMet: 0.305 ± 0.008	0.582CysAsn: 0.582 ± 0.01	0.814CysPro: 0.814 ± 0.015	0.527CysGln: 0.527 ± 0.011	0.735CysArg: 0.735 ± 0.012	1.317CysSer: 1.317 ± 0.016	0.917CysThr: 0.917 ± 0.016	0.82CysVal: 0.82 ± 0.013	0.256CysTrp: 0.256 ± 0.009	0.399CysTyr: 0.399 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.035AspAla: 4.035 ± 0.03	0.715AspCys: 0.715 ± 0.015	3.473AspAsp: 3.473 ± 0.032	3.791AspGlu: 3.791 ± 0.037	2.133AspPhe: 2.133 ± 0.023	3.898AspGly: 3.898 ± 0.039	1.21AspHis: 1.21 ± 0.017	3.208AspIle: 3.208 ± 0.028	2.252AspLys: 2.252 ± 0.023	4.859AspLeu: 4.859 ± 0.033	1.118AspMet: 1.118 ± 0.015	1.986AspAsn: 1.986 ± 0.019	3.214AspPro: 3.214 ± 0.031	1.695AspGln: 1.695 ± 0.019	2.493AspArg: 2.493 ± 0.024	4.474AspSer: 4.474 ± 0.033	2.79AspThr: 2.79 ± 0.024	3.419AspVal: 3.419 ± 0.031	0.896AspTrp: 0.896 ± 0.015	1.456AspTyr: 1.456 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	4.355GluAla: 4.355 ± 0.035	0.772GluCys: 0.772 ± 0.013	3.706GluAsp: 3.706 ± 0.036	4.957GluGlu: 4.957 ± 0.054	2.008GluPhe: 2.008 ± 0.02	3.549GluGly: 3.549 ± 0.03	1.386GluHis: 1.386 ± 0.018	3.023GluIle: 3.023 ± 0.027	3.18GluLys: 3.18 ± 0.037	5.192GluLeu: 5.192 ± 0.041	1.368GluMet: 1.368 ± 0.017	2.268GluAsn: 2.268 ± 0.024	2.509GluPro: 2.509 ± 0.027	2.305GluGln: 2.305 ± 0.027	3.305GluArg: 3.305 ± 0.034	4.203GluSer: 4.203 ± 0.035	3.064GluThr: 3.064 ± 0.024	3.526GluVal: 3.526 ± 0.032	0.924GluTrp: 0.924 ± 0.015	1.645GluTyr: 1.645 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.061PheAla: 3.061 ± 0.031	0.7PheCys: 0.7 ± 0.012	2.309PheAsp: 2.309 ± 0.022	2.079PheGlu: 2.079 ± 0.023	1.945PhePhe: 1.945 ± 0.027	2.755PheGly: 2.755 ± 0.028	1.09PheHis: 1.09 ± 0.013	2.226PheIle: 2.226 ± 0.021	1.669PheLys: 1.669 ± 0.019	3.904PheLeu: 3.904 ± 0.034	0.818PheMet: 0.818 ± 0.013	1.747PheAsn: 1.747 ± 0.02	2.253PhePro: 2.253 ± 0.024	1.517PheGln: 1.517 ± 0.016	1.952PheArg: 1.952 ± 0.02	3.939PheSer: 3.939 ± 0.029	2.465PheThr: 2.465 ± 0.025	2.601PheVal: 2.601 ± 0.023	0.663PheTrp: 0.663 ± 0.013	1.169PheTyr: 1.169 ± 0.019	0.0PheXaa: 0.0 ± 0.0
Gly	4.492GlyAla: 4.492 ± 0.037	0.868GlyCys: 0.868 ± 0.014	3.211GlyAsp: 3.211 ± 0.03	3.408GlyGlu: 3.408 ± 0.029	2.632GlyPhe: 2.632 ± 0.024	5.333GlyGly: 5.333 ± 0.069	1.91GlyHis: 1.91 ± 0.029	3.467GlyIle: 3.467 ± 0.035	3.443GlyLys: 3.443 ± 0.032	5.473GlyLeu: 5.473 ± 0.032	1.507GlyMet: 1.507 ± 0.021	2.667GlyAsn: 2.667 ± 0.026	3.072GlyPro: 3.072 ± 0.03	2.357GlyGln: 2.357 ± 0.03	3.416GlyArg: 3.416 ± 0.027	6.219GlySer: 6.219 ± 0.051	4.04GlyThr: 4.04 ± 0.038	4.044GlyVal: 4.044 ± 0.034	1.074GlyTrp: 1.074 ± 0.016	1.897GlyTyr: 1.897 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	1.727HisAla: 1.727 ± 0.018	0.444HisCys: 0.444 ± 0.01	1.172HisAsp: 1.172 ± 0.015	1.174HisGlu: 1.174 ± 0.015	1.145HisPhe: 1.145 ± 0.014	1.517HisGly: 1.517 ± 0.019	0.887HisHis: 0.887 ± 0.019	1.462HisIle: 1.462 ± 0.02	0.955HisLys: 0.955 ± 0.015	2.695HisLeu: 2.695 ± 0.026	0.488HisMet: 0.488 ± 0.01	1.011HisAsn: 1.011 ± 0.015	2.017HisPro: 2.017 ± 0.026	0.965HisGln: 0.965 ± 0.015	1.459HisArg: 1.459 ± 0.019	2.45HisSer: 2.45 ± 0.025	1.62HisThr: 1.62 ± 0.023	1.388HisVal: 1.388 ± 0.017	0.383HisTrp: 0.383 ± 0.009	0.73HisTyr: 0.73 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.225IleAla: 4.225 ± 0.031	0.905IleCys: 0.905 ± 0.013	2.766IleAsp: 2.766 ± 0.027	2.823IleGlu: 2.823 ± 0.026	2.302IlePhe: 2.302 ± 0.023	3.256IleGly: 3.256 ± 0.033	1.438IleHis: 1.438 ± 0.02	2.995IleIle: 2.995 ± 0.031	2.155IleLys: 2.155 ± 0.024	5.45IleLeu: 5.45 ± 0.038	1.064IleMet: 1.064 ± 0.017	2.03IleAsn: 2.03 ± 0.021	3.576IlePro: 3.576 ± 0.029	2.175IleGln: 2.175 ± 0.024	2.686IleArg: 2.686 ± 0.023	4.736IleSer: 4.736 ± 0.039	2.993IleThr: 2.993 ± 0.026	3.579IleVal: 3.579 ± 0.03	1.174IleTrp: 1.174 ± 0.03	1.59IleTyr: 1.59 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	3.624LysAla: 3.624 ± 0.032	0.597LysCys: 0.597 ± 0.012	2.637LysAsp: 2.637 ± 0.027	3.294LysGlu: 3.294 ± 0.031	1.642LysPhe: 1.642 ± 0.019	2.852LysGly: 2.852 ± 0.031	1.117LysHis: 1.117 ± 0.016	2.371LysIle: 2.371 ± 0.026	2.91LysLys: 2.91 ± 0.036	4.191LysLeu: 4.191 ± 0.041	1.072LysMet: 1.072 ± 0.015	1.735LysAsn: 1.735 ± 0.02	2.34LysPro: 2.34 ± 0.026	1.788LysGln: 1.788 ± 0.023	2.78LysArg: 2.78 ± 0.029	3.551LysSer: 3.551 ± 0.032	2.555LysThr: 2.555 ± 0.025	2.716LysVal: 2.716 ± 0.021	0.732LysTrp: 0.732 ± 0.011	1.33LysTyr: 1.33 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.379LeuAla: 7.379 ± 0.037	1.439LeuCys: 1.439 ± 0.017	5.188LeuAsp: 5.188 ± 0.035	5.562LeuGlu: 5.562 ± 0.044	3.786LeuPhe: 3.786 ± 0.031	5.622LeuGly: 5.622 ± 0.046	2.684LeuHis: 2.684 ± 0.025	4.585LeuIle: 4.585 ± 0.036	4.487LeuLys: 4.487 ± 0.036	9.145LeuLeu: 9.145 ± 0.063	1.858LeuMet: 1.858 ± 0.02	3.698LeuAsn: 3.698 ± 0.023	6.094LeuPro: 6.094 ± 0.042	4.218LeuGln: 4.218 ± 0.033	5.264LeuArg: 5.264 ± 0.038	8.675LeuSer: 8.675 ± 0.049	5.425LeuThr: 5.425 ± 0.044	5.773LeuVal: 5.773 ± 0.038	1.328LeuTrp: 1.328 ± 0.016	2.599LeuTyr: 2.599 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	1.768MetAla: 1.768 ± 0.021	0.258MetCys: 0.258 ± 0.007	1.207MetAsp: 1.207 ± 0.018	1.238MetGlu: 1.238 ± 0.016	0.838MetPhe: 0.838 ± 0.014	1.285MetGly: 1.285 ± 0.018	0.523MetHis: 0.523 ± 0.011	1.08MetIle: 1.08 ± 0.017	1.044MetLys: 1.044 ± 0.015	1.935MetLeu: 1.935 ± 0.02	0.504MetMet: 0.504 ± 0.01	0.932MetAsn: 0.932 ± 0.015	1.132MetPro: 1.132 ± 0.017	0.894MetGln: 0.894 ± 0.014	1.083MetArg: 1.083 ± 0.014	1.99MetSer: 1.99 ± 0.021	1.268MetThr: 1.268 ± 0.017	1.238MetVal: 1.238 ± 0.018	0.274MetTrp: 0.274 ± 0.009	0.565MetTyr: 0.565 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.391AsnAla: 3.391 ± 0.032	0.533AsnCys: 0.533 ± 0.011	2.112AsnAsp: 2.112 ± 0.023	2.15AsnGlu: 2.15 ± 0.023	1.63AsnPhe: 1.63 ± 0.017	2.879AsnGly: 2.879 ± 0.029	1.017AsnHis: 1.017 ± 0.015	2.366AsnIle: 2.366 ± 0.025	1.484AsnLys: 1.484 ± 0.018	3.881AsnLeu: 3.881 ± 0.033	0.842AsnMet: 0.842 ± 0.013	1.689AsnAsn: 1.689 ± 0.022	2.61AsnPro: 2.61 ± 0.025	1.388AsnGln: 1.388 ± 0.018	1.772AsnArg: 1.772 ± 0.018	3.6AsnSer: 3.6 ± 0.031	2.406AsnThr: 2.406 ± 0.024	2.603AsnVal: 2.603 ± 0.024	0.607AsnTrp: 0.607 ± 0.012	1.047AsnTyr: 1.047 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	4.467ProAla: 4.467 ± 0.036	0.553ProCys: 0.553 ± 0.011	3.173ProAsp: 3.173 ± 0.03	3.339ProGlu: 3.339 ± 0.027	2.382ProPhe: 2.382 ± 0.024	3.504ProGly: 3.504 ± 0.033	1.477ProHis: 1.477 ± 0.02	2.774ProIle: 2.774 ± 0.023	2.376ProLys: 2.376 ± 0.022	5.487ProLeu: 5.487 ± 0.037	1.003ProMet: 1.003 ± 0.015	2.485ProAsn: 2.485 ± 0.022	5.28ProPro: 5.28 ± 0.057	2.191ProGln: 2.191 ± 0.025	2.823ProArg: 2.823 ± 0.028	7.039ProSer: 7.039 ± 0.06	3.989ProThr: 3.989 ± 0.033	3.603ProVal: 3.603 ± 0.028	0.69ProTrp: 0.69 ± 0.012	1.543ProTyr: 1.543 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	2.945GlnAla: 2.945 ± 0.027	0.597GlnCys: 0.597 ± 0.012	1.95GlnAsp: 1.95 ± 0.02	2.216GlnGlu: 2.216 ± 0.023	1.453GlnPhe: 1.453 ± 0.017	2.287GlnGly: 2.287 ± 0.025	1.018GlnHis: 1.018 ± 0.017	2.169GlnIle: 2.169 ± 0.024	1.84GlnLys: 1.84 ± 0.019	3.707GlnLeu: 3.707 ± 0.034	0.926GlnMet: 0.926 ± 0.012	1.696GlnAsn: 1.696 ± 0.019	2.027GlnPro: 2.027 ± 0.027	1.851GlnGln: 1.851 ± 0.034	2.072GlnArg: 2.072 ± 0.022	3.313GlnSer: 3.313 ± 0.032	2.34GlnThr: 2.34 ± 0.023	2.438GlnVal: 2.438 ± 0.026	0.624GlnTrp: 0.624 ± 0.011	1.262GlnTyr: 1.262 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	3.727ArgAla: 3.727 ± 0.032	0.764ArgCys: 0.764 ± 0.014	2.683ArgAsp: 2.683 ± 0.027	3.224ArgGlu: 3.224 ± 0.032	2.063ArgPhe: 2.063 ± 0.021	3.051ArgGly: 3.051 ± 0.029	1.33ArgHis: 1.33 ± 0.015	3.21ArgIle: 3.21 ± 0.033	3.03ArgLys: 3.03 ± 0.031	4.873ArgLeu: 4.873 ± 0.037	1.212ArgMet: 1.212 ± 0.013	2.168ArgAsn: 2.168 ± 0.023	2.773ArgPro: 2.773 ± 0.026	1.979ArgGln: 1.979 ± 0.021	4.052ArgArg: 4.052 ± 0.038	4.489ArgSer: 4.489 ± 0.041	2.997ArgThr: 2.997 ± 0.025	3.148ArgVal: 3.148 ± 0.026	0.885ArgTrp: 0.885 ± 0.012	1.58ArgTyr: 1.58 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.898SerAla: 6.898 ± 0.052	1.189SerCys: 1.189 ± 0.017	4.61SerAsp: 4.61 ± 0.035	4.347SerGlu: 4.347 ± 0.031	3.787SerPhe: 3.787 ± 0.028	6.166SerGly: 6.166 ± 0.051	2.237SerHis: 2.237 ± 0.024	4.717SerIle: 4.717 ± 0.03	3.786SerLys: 3.786 ± 0.026	8.787SerLeu: 8.787 ± 0.052	1.851SerMet: 1.851 ± 0.021	3.745SerAsn: 3.745 ± 0.032	6.267SerPro: 6.267 ± 0.059	3.437SerGln: 3.437 ± 0.031	4.909SerArg: 4.909 ± 0.048	11.984SerSer: 11.984 ± 0.099	6.467SerThr: 6.467 ± 0.053	5.571SerVal: 5.571 ± 0.049	1.156SerTrp: 1.156 ± 0.016	2.245SerTyr: 2.245 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	4.564ThrAla: 4.564 ± 0.032	0.849ThrCys: 0.849 ± 0.013	2.666ThrAsp: 2.666 ± 0.023	2.825ThrGlu: 2.825 ± 0.025	2.632ThrPhe: 2.632 ± 0.023	4.22ThrGly: 4.22 ± 0.039	1.424ThrHis: 1.424 ± 0.017	3.39ThrIle: 3.39 ± 0.028	2.334ThrLys: 2.334 ± 0.021	5.931ThrLeu: 5.931 ± 0.042	1.168ThrMet: 1.168 ± 0.015	2.23ThrAsn: 2.23 ± 0.027	4.024ThrPro: 4.024 ± 0.039	2.089ThrGln: 2.089 ± 0.021	2.864ThrArg: 2.864 ± 0.025	6.184ThrSer: 6.184 ± 0.052	4.156ThrThr: 4.156 ± 0.042	4.121ThrVal: 4.121 ± 0.032	0.833ThrTrp: 0.833 ± 0.012	1.665ThrTyr: 1.665 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	4.975ValAla: 4.975 ± 0.036	0.927ValCys: 0.927 ± 0.016	3.464ValAsp: 3.464 ± 0.029	3.633ValGlu: 3.633 ± 0.029	2.62ValPhe: 2.62 ± 0.028	3.776ValGly: 3.776 ± 0.034	1.565ValHis: 1.565 ± 0.019	3.341ValIle: 3.341 ± 0.03	2.832ValLys: 2.832 ± 0.027	5.953ValLeu: 5.953 ± 0.037	1.298ValMet: 1.298 ± 0.016	2.468ValAsn: 2.468 ± 0.023	3.74ValPro: 3.74 ± 0.028	2.597ValGln: 2.597 ± 0.025	3.173ValArg: 3.173 ± 0.032	5.27ValSer: 5.27 ± 0.04	3.574ValThr: 3.574 ± 0.028	4.357ValVal: 4.357 ± 0.031	0.991ValTrp: 0.991 ± 0.016	1.811ValTyr: 1.811 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.096TrpAla: 1.096 ± 0.015	0.214TrpCys: 0.214 ± 0.007	1.122TrpAsp: 1.122 ± 0.027	0.851TrpGlu: 0.851 ± 0.013	0.597TrpPhe: 0.597 ± 0.011	0.851TrpGly: 0.851 ± 0.012	0.35TrpHis: 0.35 ± 0.009	0.949TrpIle: 0.949 ± 0.014	0.941TrpLys: 0.941 ± 0.014	1.336TrpLeu: 1.336 ± 0.017	0.395TrpMet: 0.395 ± 0.009	0.858TrpAsn: 0.858 ± 0.019	0.606TrpPro: 0.606 ± 0.009	0.496TrpGln: 0.496 ± 0.009	0.931TrpArg: 0.931 ± 0.014	1.117TrpSer: 1.117 ± 0.016	0.938TrpThr: 0.938 ± 0.014	0.969TrpVal: 0.969 ± 0.014	0.27TrpTrp: 0.27 ± 0.008	0.41TrpTyr: 0.41 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.03TyrAla: 2.03 ± 0.021	0.499TyrCys: 0.499 ± 0.01	1.532TyrAsp: 1.532 ± 0.019	1.395TyrGlu: 1.395 ± 0.018	1.244TyrPhe: 1.244 ± 0.016	1.894TyrGly: 1.894 ± 0.02	0.859TyrHis: 0.859 ± 0.014	1.587TyrIle: 1.587 ± 0.02	1.074TyrLys: 1.074 ± 0.014	2.723TyrLeu: 2.723 ± 0.023	0.57TyrMet: 0.57 ± 0.011	1.202TyrAsn: 1.202 ± 0.016	1.679TyrPro: 1.679 ± 0.017	1.056TyrGln: 1.056 ± 0.015	1.531TyrArg: 1.531 ± 0.018	2.46TyrSer: 2.46 ± 0.032	1.626TyrThr: 1.626 ± 0.018	1.622TyrVal: 1.622 ± 0.023	0.46TyrTrp: 0.46 ± 0.01	0.91TyrTyr: 0.91 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 14588 proteins (4980570 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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