Amino acid dipepetide frequency for Acidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp. citrulli)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.195AlaAla: 21.195 ± 0.174	1.545AlaCys: 1.545 ± 0.035	6.669AlaAsp: 6.669 ± 0.066	7.058AlaGlu: 7.058 ± 0.078	4.002AlaPhe: 4.002 ± 0.052	12.548AlaGly: 12.548 ± 0.113	2.944AlaHis: 2.944 ± 0.041	4.883AlaIle: 4.883 ± 0.063	3.123AlaLys: 3.123 ± 0.072	15.602AlaLeu: 15.602 ± 0.134	3.583AlaMet: 3.583 ± 0.051	2.423AlaAsn: 2.423 ± 0.048	7.812AlaPro: 7.812 ± 0.095	6.186AlaGln: 6.186 ± 0.073	11.105AlaArg: 11.105 ± 0.108	7.133AlaSer: 7.133 ± 0.085	6.365AlaThr: 6.365 ± 0.07	9.644AlaVal: 9.644 ± 0.091	2.226AlaTrp: 2.226 ± 0.046	2.48AlaTyr: 2.48 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	1.268CysAla: 1.268 ± 0.026	0.115CysCys: 0.115 ± 0.008	0.548CysAsp: 0.548 ± 0.018	0.509CysGlu: 0.509 ± 0.018	0.301CysPhe: 0.301 ± 0.014	1.018CysGly: 1.018 ± 0.027	0.249CysHis: 0.249 ± 0.014	0.41CysIle: 0.41 ± 0.018	0.189CysLys: 0.189 ± 0.012	0.893CysLeu: 0.893 ± 0.025	0.246CysMet: 0.246 ± 0.014	0.205CysAsn: 0.205 ± 0.012	0.515CysPro: 0.515 ± 0.021	0.259CysGln: 0.259 ± 0.013	0.684CysArg: 0.684 ± 0.021	0.509CysSer: 0.509 ± 0.019	0.525CysThr: 0.525 ± 0.022	0.723CysVal: 0.723 ± 0.019	0.14CysTrp: 0.14 ± 0.011	0.195CysTyr: 0.195 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.747AspAla: 7.747 ± 0.079	0.451AspCys: 0.451 ± 0.018	2.547AspAsp: 2.547 ± 0.043	2.884AspGlu: 2.884 ± 0.042	1.975AspPhe: 1.975 ± 0.043	4.975AspGly: 4.975 ± 0.07	1.129AspHis: 1.129 ± 0.028	2.272AspIle: 2.272 ± 0.042	1.448AspLys: 1.448 ± 0.035	5.088AspLeu: 5.088 ± 0.059	1.203AspMet: 1.203 ± 0.028	1.083AspAsn: 1.083 ± 0.026	3.056AspPro: 3.056 ± 0.05	1.473AspGln: 1.473 ± 0.031	3.728AspArg: 3.728 ± 0.051	2.088AspSer: 2.088 ± 0.039	2.607AspThr: 2.607 ± 0.043	3.905AspVal: 3.905 ± 0.048	0.961AspTrp: 0.961 ± 0.026	1.307AspTyr: 1.307 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	7.247GluAla: 7.247 ± 0.086	0.415GluCys: 0.415 ± 0.015	2.412GluAsp: 2.412 ± 0.044	2.678GluGlu: 2.678 ± 0.045	1.615GluPhe: 1.615 ± 0.035	4.213GluGly: 4.213 ± 0.056	1.334GluHis: 1.334 ± 0.034	2.431GluIle: 2.431 ± 0.042	1.624GluLys: 1.624 ± 0.039	5.323GluLeu: 5.323 ± 0.072	1.182GluMet: 1.182 ± 0.029	1.194GluAsn: 1.194 ± 0.029	2.691GluPro: 2.691 ± 0.042	2.502GluGln: 2.502 ± 0.041	5.012GluArg: 5.012 ± 0.066	2.58GluSer: 2.58 ± 0.04	2.402GluThr: 2.402 ± 0.042	3.805GluVal: 3.805 ± 0.049	0.746GluTrp: 0.746 ± 0.024	1.011GluTyr: 1.011 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	4.077PheAla: 4.077 ± 0.055	0.371PheCys: 0.371 ± 0.018	2.263PheAsp: 2.263 ± 0.039	1.78PheGlu: 1.78 ± 0.034	1.233PhePhe: 1.233 ± 0.034	3.154PheGly: 3.154 ± 0.049	0.789PheHis: 0.789 ± 0.026	1.354PheIle: 1.354 ± 0.034	0.947PheLys: 0.947 ± 0.027	2.843PheLeu: 2.843 ± 0.045	0.729PheMet: 0.729 ± 0.023	0.919PheAsn: 0.919 ± 0.026	1.494PhePro: 1.494 ± 0.029	1.093PheGln: 1.093 ± 0.025	1.914PheArg: 1.914 ± 0.034	2.036PheSer: 2.036 ± 0.041	1.795PheThr: 1.795 ± 0.034	2.495PheVal: 2.495 ± 0.043	0.505PheTrp: 0.505 ± 0.019	0.794PheTyr: 0.794 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	10.677GlyAla: 10.677 ± 0.102	0.911GlyCys: 0.911 ± 0.026	4.233GlyAsp: 4.233 ± 0.057	4.49GlyGlu: 4.49 ± 0.057	3.11GlyPhe: 3.11 ± 0.043	8.074GlyGly: 8.074 ± 0.113	2.149GlyHis: 2.149 ± 0.037	3.841GlyIle: 3.841 ± 0.054	2.829GlyLys: 2.829 ± 0.055	8.833GlyLeu: 8.833 ± 0.083	2.507GlyMet: 2.507 ± 0.039	2.088GlyAsn: 2.088 ± 0.046	3.802GlyPro: 3.802 ± 0.05	3.48GlyGln: 3.48 ± 0.055	6.729GlyArg: 6.729 ± 0.082	4.768GlySer: 4.768 ± 0.067	5.167GlyThr: 5.167 ± 0.07	6.379GlyVal: 6.379 ± 0.065	1.583GlyTrp: 1.583 ± 0.038	2.222GlyTyr: 2.222 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	3.435HisAla: 3.435 ± 0.05	0.292HisCys: 0.292 ± 0.014	1.184HisAsp: 1.184 ± 0.036	1.119HisGlu: 1.119 ± 0.028	0.839HisPhe: 0.839 ± 0.022	2.36HisGly: 2.36 ± 0.045	0.644HisHis: 0.644 ± 0.021	0.933HisIle: 0.933 ± 0.026	0.512HisLys: 0.512 ± 0.018	2.281HisLeu: 2.281 ± 0.048	0.485HisMet: 0.485 ± 0.021	0.432HisAsn: 0.432 ± 0.015	1.655HisPro: 1.655 ± 0.035	0.767HisGln: 0.767 ± 0.025	1.764HisArg: 1.764 ± 0.043	1.058HisSer: 1.058 ± 0.025	1.091HisThr: 1.091 ± 0.031	1.634HisVal: 1.634 ± 0.03	0.456HisTrp: 0.456 ± 0.019	0.629HisTyr: 0.629 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.978IleAla: 5.978 ± 0.059	0.369IleCys: 0.369 ± 0.015	2.866IleAsp: 2.866 ± 0.044	2.65IleGlu: 2.65 ± 0.042	1.073IlePhe: 1.073 ± 0.028	3.806IleGly: 3.806 ± 0.051	0.869IleHis: 0.869 ± 0.025	1.248IleIle: 1.248 ± 0.032	1.122IleLys: 1.122 ± 0.033	2.938IleLeu: 2.938 ± 0.046	0.634IleMet: 0.634 ± 0.02	1.102IleAsn: 1.102 ± 0.03	1.935IlePro: 1.935 ± 0.036	1.284IleGln: 1.284 ± 0.027	2.463IleArg: 2.463 ± 0.042	1.905IleSer: 1.905 ± 0.037	2.176IleThr: 2.176 ± 0.04	3.2IleVal: 3.2 ± 0.05	0.421IleTrp: 0.421 ± 0.018	0.869IleTyr: 0.869 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	3.511LysAla: 3.511 ± 0.068	0.143LysCys: 0.143 ± 0.009	1.474LysAsp: 1.474 ± 0.036	1.387LysGlu: 1.387 ± 0.041	0.756LysPhe: 0.756 ± 0.026	2.11LysGly: 2.11 ± 0.046	0.51LysHis: 0.51 ± 0.021	1.257LysIle: 1.257 ± 0.026	1.113LysLys: 1.113 ± 0.041	2.658LysLeu: 2.658 ± 0.054	0.641LysMet: 0.641 ± 0.021	0.765LysAsn: 0.765 ± 0.022	1.682LysPro: 1.682 ± 0.035	0.943LysGln: 0.943 ± 0.026	1.746LysArg: 1.746 ± 0.038	1.479LysSer: 1.479 ± 0.034	1.606LysThr: 1.606 ± 0.039	2.117LysVal: 2.117 ± 0.042	0.281LysTrp: 0.281 ± 0.015	0.542LysTyr: 0.542 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	14.909LeuAla: 14.909 ± 0.123	1.086LeuCys: 1.086 ± 0.026	5.482LeuAsp: 5.482 ± 0.07	5.163LeuGlu: 5.163 ± 0.077	3.066LeuPhe: 3.066 ± 0.054	8.522LeuGly: 8.522 ± 0.094	2.567LeuHis: 2.567 ± 0.043	3.491LeuIle: 3.491 ± 0.052	2.784LeuLys: 2.784 ± 0.052	10.697LeuLeu: 10.697 ± 0.113	2.149LeuMet: 2.149 ± 0.044	2.245LeuAsn: 2.245 ± 0.037	6.652LeuPro: 6.652 ± 0.078	4.797LeuGln: 4.797 ± 0.063	8.677LeuArg: 8.677 ± 0.089	5.725LeuSer: 5.725 ± 0.062	4.601LeuThr: 4.601 ± 0.053	7.517LeuVal: 7.517 ± 0.079	1.368LeuTrp: 1.368 ± 0.031	1.913LeuTyr: 1.913 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	3.311MetAla: 3.311 ± 0.047	0.15MetCys: 0.15 ± 0.011	1.221MetAsp: 1.221 ± 0.032	1.19MetGlu: 1.19 ± 0.027	0.624MetPhe: 0.624 ± 0.022	1.855MetGly: 1.855 ± 0.036	0.591MetHis: 0.591 ± 0.019	0.738MetIle: 0.738 ± 0.023	0.796MetLys: 0.796 ± 0.021	2.486MetLeu: 2.486 ± 0.041	0.488MetMet: 0.488 ± 0.021	0.699MetAsn: 0.699 ± 0.021	1.625MetPro: 1.625 ± 0.034	1.091MetGln: 1.091 ± 0.025	1.775MetArg: 1.775 ± 0.037	1.314MetSer: 1.314 ± 0.03	1.383MetThr: 1.383 ± 0.03	1.732MetVal: 1.732 ± 0.034	0.196MetTrp: 0.196 ± 0.011	0.342MetTyr: 0.342 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.01AsnAla: 3.01 ± 0.044	0.217AsnCys: 0.217 ± 0.012	1.157AsnAsp: 1.157 ± 0.029	1.017AsnGlu: 1.017 ± 0.027	0.813AsnPhe: 0.813 ± 0.025	1.994AsnGly: 1.994 ± 0.041	0.491AsnHis: 0.491 ± 0.016	1.017AsnIle: 1.017 ± 0.025	0.622AsnLys: 0.622 ± 0.022	2.179AsnLeu: 2.179 ± 0.037	0.49AsnMet: 0.49 ± 0.018	0.615AsnAsn: 0.615 ± 0.024	1.634AsnPro: 1.634 ± 0.036	0.772AsnGln: 0.772 ± 0.026	1.548AsnArg: 1.548 ± 0.032	0.998AsnSer: 0.998 ± 0.031	1.198AsnThr: 1.198 ± 0.033	1.698AsnVal: 1.698 ± 0.036	0.359AsnTrp: 0.359 ± 0.015	0.59AsnTyr: 0.59 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	9.231ProAla: 9.231 ± 0.107	0.431ProCys: 0.431 ± 0.016	3.404ProAsp: 3.404 ± 0.051	3.532ProGlu: 3.532 ± 0.046	1.792ProPhe: 1.792 ± 0.031	5.694ProGly: 5.694 ± 0.067	1.28ProHis: 1.28 ± 0.029	1.695ProIle: 1.695 ± 0.037	1.167ProLys: 1.167 ± 0.031	5.57ProLeu: 5.57 ± 0.064	1.365ProMet: 1.365 ± 0.032	1.056ProAsn: 1.056 ± 0.028	3.642ProPro: 3.642 ± 0.073	2.323ProGln: 2.323 ± 0.039	3.847ProArg: 3.847 ± 0.056	3.158ProSer: 3.158 ± 0.043	2.429ProThr: 2.429 ± 0.042	4.526ProVal: 4.526 ± 0.058	0.873ProTrp: 0.873 ± 0.025	1.129ProTyr: 1.129 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	6.275GlnAla: 6.275 ± 0.08	0.322GlnCys: 0.322 ± 0.015	1.928GlnAsp: 1.928 ± 0.036	1.948GlnGlu: 1.948 ± 0.037	1.198GlnPhe: 1.198 ± 0.03	3.467GlnGly: 3.467 ± 0.056	0.927GlnHis: 0.927 ± 0.026	1.619GlnIle: 1.619 ± 0.031	1.04GlnLys: 1.04 ± 0.026	3.949GlnLeu: 3.949 ± 0.056	0.923GlnMet: 0.923 ± 0.028	0.843GlnAsn: 0.843 ± 0.027	2.581GlnPro: 2.581 ± 0.041	1.96GlnGln: 1.96 ± 0.039	3.66GlnArg: 3.66 ± 0.052	2.0GlnSer: 2.0 ± 0.033	1.643GlnThr: 1.643 ± 0.03	3.006GlnVal: 3.006 ± 0.042	0.713GlnTrp: 0.713 ± 0.022	0.791GlnTyr: 0.791 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	9.288ArgAla: 9.288 ± 0.092	0.703ArgCys: 0.703 ± 0.024	3.768ArgAsp: 3.768 ± 0.052	4.47ArgGlu: 4.47 ± 0.061	2.768ArgPhe: 2.768 ± 0.049	5.448ArgGly: 5.448 ± 0.065	2.292ArgHis: 2.292 ± 0.047	3.632ArgIle: 3.632 ± 0.049	2.043ArgLys: 2.043 ± 0.04	8.454ArgLeu: 8.454 ± 0.088	2.186ArgMet: 2.186 ± 0.039	1.743ArgAsn: 1.743 ± 0.035	4.118ArgPro: 4.118 ± 0.057	3.437ArgGln: 3.437 ± 0.047	6.211ArgArg: 6.211 ± 0.089	3.789ArgSer: 3.789 ± 0.046	3.954ArgThr: 3.954 ± 0.053	5.141ArgVal: 5.141 ± 0.067	1.442ArgTrp: 1.442 ± 0.039	1.921ArgTyr: 1.921 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	6.924SerAla: 6.924 ± 0.083	0.45SerCys: 0.45 ± 0.019	2.552SerAsp: 2.552 ± 0.041	2.41SerGlu: 2.41 ± 0.047	1.868SerPhe: 1.868 ± 0.037	5.281SerGly: 5.281 ± 0.066	1.175SerHis: 1.175 ± 0.026	2.115SerIle: 2.115 ± 0.041	1.192SerLys: 1.192 ± 0.032	5.287SerLeu: 5.287 ± 0.063	1.28SerMet: 1.28 ± 0.031	1.146SerAsn: 1.146 ± 0.029	3.18SerPro: 3.18 ± 0.045	1.841SerGln: 1.841 ± 0.034	3.662SerArg: 3.662 ± 0.05	3.138SerSer: 3.138 ± 0.061	2.839SerThr: 2.839 ± 0.042	3.828SerVal: 3.828 ± 0.056	0.692SerTrp: 0.692 ± 0.021	1.113SerTyr: 1.113 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	6.505ThrAla: 6.505 ± 0.068	0.387ThrCys: 0.387 ± 0.018	2.477ThrAsp: 2.477 ± 0.042	2.324ThrGlu: 2.324 ± 0.041	1.59ThrPhe: 1.59 ± 0.034	4.865ThrGly: 4.865 ± 0.065	1.137ThrHis: 1.137 ± 0.03	1.89ThrIle: 1.89 ± 0.041	1.103ThrLys: 1.103 ± 0.031	5.783ThrLeu: 5.783 ± 0.056	1.006ThrMet: 1.006 ± 0.023	1.053ThrAsn: 1.053 ± 0.029	3.55ThrPro: 3.55 ± 0.049	1.917ThrGln: 1.917 ± 0.036	3.29ThrArg: 3.29 ± 0.048	2.563ThrSer: 2.563 ± 0.038	2.683ThrThr: 2.683 ± 0.052	4.262ThrVal: 4.262 ± 0.059	0.686ThrTrp: 0.686 ± 0.021	1.033ThrTyr: 1.033 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	9.777ValAla: 9.777 ± 0.092	0.719ValCys: 0.719 ± 0.022	3.791ValAsp: 3.791 ± 0.05	4.068ValGlu: 4.068 ± 0.055	2.599ValPhe: 2.599 ± 0.043	5.502ValGly: 5.502 ± 0.07	1.7ValHis: 1.7 ± 0.029	2.789ValIle: 2.789 ± 0.056	2.017ValLys: 2.017 ± 0.041	8.222ValLeu: 8.222 ± 0.087	1.664ValMet: 1.664 ± 0.036	1.852ValAsn: 1.852 ± 0.032	4.617ValPro: 4.617 ± 0.064	3.15ValGln: 3.15 ± 0.046	5.814ValArg: 5.814 ± 0.064	3.779ValSer: 3.779 ± 0.048	3.723ValThr: 3.723 ± 0.049	6.184ValVal: 6.184 ± 0.068	0.957ValTrp: 0.957 ± 0.023	1.405ValTyr: 1.405 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.568TrpAla: 1.568 ± 0.034	0.188TrpCys: 0.188 ± 0.011	0.673TrpAsp: 0.673 ± 0.024	0.606TrpGlu: 0.606 ± 0.02	0.529TrpPhe: 0.529 ± 0.019	1.023TrpGly: 1.023 ± 0.026	0.356TrpHis: 0.356 ± 0.013	0.634TrpIle: 0.634 ± 0.022	0.485TrpLys: 0.485 ± 0.021	2.067TrpLeu: 2.067 ± 0.045	0.453TrpMet: 0.453 ± 0.018	0.427TrpAsn: 0.427 ± 0.015	0.835TrpPro: 0.835 ± 0.025	0.734TrpGln: 0.734 ± 0.022	1.4TrpArg: 1.4 ± 0.035	0.88TrpSer: 0.88 ± 0.026	0.799TrpThr: 0.799 ± 0.025	1.016TrpVal: 1.016 ± 0.025	0.307TrpTrp: 0.307 ± 0.016	0.276TrpTyr: 0.276 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.594TyrAla: 2.594 ± 0.044	0.236TyrCys: 0.236 ± 0.012	1.277TyrAsp: 1.277 ± 0.036	1.135TyrGlu: 1.135 ± 0.032	0.833TyrPhe: 0.833 ± 0.024	1.964TyrGly: 1.964 ± 0.036	0.437TyrHis: 0.437 ± 0.017	0.66TyrIle: 0.66 ± 0.02	0.565TyrLys: 0.565 ± 0.023	2.26TyrLeu: 2.26 ± 0.038	0.393TyrMet: 0.393 ± 0.017	0.528TyrAsn: 0.528 ± 0.019	1.066TyrPro: 1.066 ± 0.028	0.783TyrGln: 0.783 ± 0.023	1.778TyrArg: 1.778 ± 0.031	1.075TyrSer: 1.075 ± 0.027	1.12TyrThr: 1.12 ± 0.031	1.515TyrVal: 1.515 ± 0.035	0.344TyrTrp: 0.344 ± 0.015	0.567TyrTyr: 0.567 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4602 proteins (1557338 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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