Amino acid dipepetide frequency for Ananas comosus (Pineapple) (Ananas ananas)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.673AlaAla: 11.673 ± 0.072	1.422AlaCys: 1.422 ± 0.016	3.817AlaAsp: 3.817 ± 0.024	5.244AlaGlu: 5.244 ± 0.033	3.052AlaPhe: 3.052 ± 0.019	5.268AlaGly: 5.268 ± 0.034	1.596AlaHis: 1.596 ± 0.014	3.883AlaIle: 3.883 ± 0.023	3.935AlaLys: 3.935 ± 0.023	7.97AlaLeu: 7.97 ± 0.038	1.944AlaMet: 1.944 ± 0.015	2.662AlaAsn: 2.662 ± 0.016	3.935AlaPro: 3.935 ± 0.027	2.232AlaGln: 2.232 ± 0.017	4.7AlaArg: 4.7 ± 0.029	6.809AlaSer: 6.809 ± 0.029	3.909AlaThr: 3.909 ± 0.023	5.936AlaVal: 5.936 ± 0.034	0.858AlaTrp: 0.858 ± 0.01	1.957AlaTyr: 1.957 ± 0.016	0.0AlaXaa: 0.0 ± 0.0
Cys	1.23CysAla: 1.23 ± 0.013	0.545CysCys: 0.545 ± 0.008	0.84CysAsp: 0.84 ± 0.011	0.874CysGlu: 0.874 ± 0.01	0.84CysPhe: 0.84 ± 0.01	1.541CysGly: 1.541 ± 0.015	0.416CysHis: 0.416 ± 0.007	0.886CysIle: 0.886 ± 0.01	0.966CysLys: 0.966 ± 0.013	1.702CysLeu: 1.702 ± 0.015	0.42CysMet: 0.42 ± 0.008	0.73CysAsn: 0.73 ± 0.009	0.965CysPro: 0.965 ± 0.011	0.487CysGln: 0.487 ± 0.008	1.23CysArg: 1.23 ± 0.012	1.833CysSer: 1.833 ± 0.016	0.83CysThr: 0.83 ± 0.011	1.061CysVal: 1.061 ± 0.01	0.253CysTrp: 0.253 ± 0.005	0.519CysTyr: 0.519 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.181AspAla: 4.181 ± 0.023	0.914AspCys: 0.914 ± 0.01	3.685AspAsp: 3.685 ± 0.029	3.971AspGlu: 3.971 ± 0.024	2.135AspPhe: 2.135 ± 0.016	4.003AspGly: 4.003 ± 0.024	1.175AspHis: 1.175 ± 0.011	2.611AspIle: 2.611 ± 0.019	2.32AspLys: 2.32 ± 0.017	5.197AspLeu: 5.197 ± 0.027	1.168AspMet: 1.168 ± 0.012	1.754AspAsn: 1.754 ± 0.015	2.906AspPro: 2.906 ± 0.022	1.541AspGln: 1.541 ± 0.015	2.793AspArg: 2.793 ± 0.021	3.827AspSer: 3.827 ± 0.024	1.944AspThr: 1.944 ± 0.014	3.571AspVal: 3.571 ± 0.021	0.701AspTrp: 0.701 ± 0.007	1.483AspTyr: 1.483 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	5.376GluAla: 5.376 ± 0.033	0.868GluCys: 0.868 ± 0.01	3.597GluAsp: 3.597 ± 0.024	6.864GluGlu: 6.864 ± 0.053	2.228GluPhe: 2.228 ± 0.016	4.134GluGly: 4.134 ± 0.026	1.267GluHis: 1.267 ± 0.012	3.592GluIle: 3.592 ± 0.021	4.468GluLys: 4.468 ± 0.029	6.037GluLeu: 6.037 ± 0.036	1.752GluMet: 1.752 ± 0.013	2.676GluAsn: 2.676 ± 0.02	2.278GluPro: 2.278 ± 0.016	2.04GluGln: 2.04 ± 0.018	3.953GluArg: 3.953 ± 0.026	4.28GluSer: 4.28 ± 0.023	2.726GluThr: 2.726 ± 0.018	4.061GluVal: 4.061 ± 0.024	0.786GluTrp: 0.786 ± 0.01	1.574GluTyr: 1.574 ± 0.014	0.0GluXaa: 0.0 ± 0.0
Phe	2.976PheAla: 2.976 ± 0.019	0.814PheCys: 0.814 ± 0.01	2.396PheAsp: 2.396 ± 0.017	2.196PheGlu: 2.196 ± 0.016	1.933PhePhe: 1.933 ± 0.019	3.052PheGly: 3.052 ± 0.022	1.019PheHis: 1.019 ± 0.011	1.782PheIle: 1.782 ± 0.014	1.72PheLys: 1.72 ± 0.015	4.161PheLeu: 4.161 ± 0.026	0.836PheMet: 0.836 ± 0.009	1.469PheAsn: 1.469 ± 0.013	2.048PhePro: 2.048 ± 0.016	1.261PheGln: 1.261 ± 0.012	2.222PheArg: 2.222 ± 0.016	3.768PheSer: 3.768 ± 0.023	1.821PheThr: 1.821 ± 0.015	2.798PheVal: 2.798 ± 0.021	0.527PheTrp: 0.527 ± 0.008	1.201PheTyr: 1.201 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	5.224GlyAla: 5.224 ± 0.031	1.333GlyCys: 1.333 ± 0.015	3.726GlyAsp: 3.726 ± 0.019	4.212GlyGlu: 4.212 ± 0.028	3.112GlyPhe: 3.112 ± 0.023	7.364GlyGly: 7.364 ± 0.055	1.505GlyHis: 1.505 ± 0.015	3.368GlyIle: 3.368 ± 0.022	3.659GlyLys: 3.659 ± 0.02	6.155GlyLeu: 6.155 ± 0.032	1.474GlyMet: 1.474 ± 0.015	2.738GlyAsn: 2.738 ± 0.02	2.877GlyPro: 2.877 ± 0.021	1.874GlyGln: 1.874 ± 0.014	4.531GlyArg: 4.531 ± 0.026	5.944GlySer: 5.944 ± 0.028	3.147GlyThr: 3.147 ± 0.022	4.412GlyVal: 4.412 ± 0.022	0.961GlyTrp: 0.961 ± 0.011	2.043GlyTyr: 2.043 ± 0.016	0.0GlyXaa: 0.0 ± 0.0
His	1.647HisAla: 1.647 ± 0.015	0.505HisCys: 0.505 ± 0.008	1.105HisAsp: 1.105 ± 0.012	1.209HisGlu: 1.209 ± 0.012	1.011HisPhe: 1.011 ± 0.01	1.76HisGly: 1.76 ± 0.016	1.02HisHis: 1.02 ± 0.017	1.095HisIle: 1.095 ± 0.012	0.988HisLys: 0.988 ± 0.011	2.502HisLeu: 2.502 ± 0.016	0.496HisMet: 0.496 ± 0.008	0.845HisAsn: 0.845 ± 0.011	1.465HisPro: 1.465 ± 0.014	0.843HisGln: 0.843 ± 0.01	1.571HisArg: 1.571 ± 0.016	1.778HisSer: 1.778 ± 0.014	0.884HisThr: 0.884 ± 0.01	1.502HisVal: 1.502 ± 0.015	0.29HisTrp: 0.29 ± 0.006	0.697HisTyr: 0.697 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	3.76IleAla: 3.76 ± 0.025	0.991IleCys: 0.991 ± 0.011	2.667IleAsp: 2.667 ± 0.018	2.994IleGlu: 2.994 ± 0.017	2.003IlePhe: 2.003 ± 0.015	3.265IleGly: 3.265 ± 0.022	1.187IleHis: 1.187 ± 0.011	2.454IleIle: 2.454 ± 0.018	2.537IleLys: 2.537 ± 0.016	4.875IleLeu: 4.875 ± 0.029	1.021IleMet: 1.021 ± 0.011	1.875IleAsn: 1.875 ± 0.014	2.871IlePro: 2.871 ± 0.026	1.676IleGln: 1.676 ± 0.015	2.693IleArg: 2.693 ± 0.019	4.388IleSer: 4.388 ± 0.026	2.41IleThr: 2.41 ± 0.018	3.266IleVal: 3.266 ± 0.022	0.626IleTrp: 0.626 ± 0.009	1.411IleTyr: 1.411 ± 0.013	0.0IleXaa: 0.0 ± 0.0
Lys	3.93LysAla: 3.93 ± 0.025	0.844LysCys: 0.844 ± 0.009	2.812LysAsp: 2.812 ± 0.021	4.285LysGlu: 4.285 ± 0.029	1.8LysPhe: 1.8 ± 0.017	3.376LysGly: 3.376 ± 0.024	1.184LysHis: 1.184 ± 0.012	2.748LysIle: 2.748 ± 0.02	4.058LysLys: 4.058 ± 0.035	5.329LysLeu: 5.329 ± 0.031	1.318LysMet: 1.318 ± 0.013	2.167LysAsn: 2.167 ± 0.016	2.516LysPro: 2.516 ± 0.018	1.952LysGln: 1.952 ± 0.016	3.444LysArg: 3.444 ± 0.021	3.924LysSer: 3.924 ± 0.026	2.27LysThr: 2.27 ± 0.016	3.275LysVal: 3.275 ± 0.02	0.703LysTrp: 0.703 ± 0.009	1.437LysTyr: 1.437 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	7.592LeuAla: 7.592 ± 0.033	1.859LeuCys: 1.859 ± 0.016	5.142LeuAsp: 5.142 ± 0.03	6.002LeuGlu: 6.002 ± 0.035	3.958LeuPhe: 3.958 ± 0.025	6.107LeuGly: 6.107 ± 0.032	2.651LeuHis: 2.651 ± 0.018	4.364LeuIle: 4.364 ± 0.024	5.337LeuLys: 5.337 ± 0.027	11.225LeuLeu: 11.225 ± 0.047	2.022LeuMet: 2.022 ± 0.015	3.526LeuAsn: 3.526 ± 0.025	5.7LeuPro: 5.7 ± 0.029	4.018LeuGln: 4.018 ± 0.027	6.74LeuArg: 6.74 ± 0.03	8.868LeuSer: 8.868 ± 0.056	4.309LeuThr: 4.309 ± 0.027	6.358LeuVal: 6.358 ± 0.03	1.178LeuTrp: 1.178 ± 0.013	2.482LeuTyr: 2.482 ± 0.017	0.0LeuXaa: 0.0 ± 0.0
Met	2.249MetAla: 2.249 ± 0.016	0.297MetCys: 0.297 ± 0.006	1.253MetAsp: 1.253 ± 0.012	1.797MetGlu: 1.797 ± 0.016	0.698MetPhe: 0.698 ± 0.009	1.553MetGly: 1.553 ± 0.016	0.502MetHis: 0.502 ± 0.008	1.094MetIle: 1.094 ± 0.014	1.331MetLys: 1.331 ± 0.014	2.172MetLeu: 2.172 ± 0.017	0.606MetMet: 0.606 ± 0.009	0.867MetAsn: 0.867 ± 0.01	1.077MetPro: 1.077 ± 0.012	0.849MetGln: 0.849 ± 0.01	1.367MetArg: 1.367 ± 0.012	1.58MetSer: 1.58 ± 0.013	0.926MetThr: 0.926 ± 0.011	1.515MetVal: 1.515 ± 0.013	0.263MetTrp: 0.263 ± 0.005	0.596MetTyr: 0.596 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.66AsnAla: 2.66 ± 0.019	0.792AsnCys: 0.792 ± 0.009	1.71AsnAsp: 1.71 ± 0.014	2.17AsnGlu: 2.17 ± 0.017	1.666AsnPhe: 1.666 ± 0.017	2.9AsnGly: 2.9 ± 0.02	0.899AsnHis: 0.899 ± 0.009	2.159AsnIle: 2.159 ± 0.016	1.952AsnLys: 1.952 ± 0.016	4.186AsnLeu: 4.186 ± 0.037	0.944AsnMet: 0.944 ± 0.011	1.996AsnAsn: 1.996 ± 0.028	2.329AsnPro: 2.329 ± 0.018	1.316AsnGln: 1.316 ± 0.014	1.948AsnArg: 1.948 ± 0.017	3.457AsnSer: 3.457 ± 0.024	1.773AsnThr: 1.773 ± 0.015	2.348AsnVal: 2.348 ± 0.017	0.501AsnTrp: 0.501 ± 0.008	1.156AsnTyr: 1.156 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	4.091ProAla: 4.091 ± 0.026	0.803ProCys: 0.803 ± 0.011	2.659ProAsp: 2.659 ± 0.019	3.136ProGlu: 3.136 ± 0.021	2.118ProPhe: 2.118 ± 0.014	2.891ProGly: 2.891 ± 0.022	1.267ProHis: 1.267 ± 0.013	2.323ProIle: 2.323 ± 0.014	2.465ProLys: 2.465 ± 0.017	4.939ProLeu: 4.939 ± 0.027	0.922ProMet: 0.922 ± 0.01	2.244ProAsn: 2.244 ± 0.017	5.46ProPro: 5.46 ± 0.055	1.786ProGln: 1.786 ± 0.015	3.162ProArg: 3.162 ± 0.023	5.8ProSer: 5.8 ± 0.029	2.796ProThr: 2.796 ± 0.022	3.014ProVal: 3.014 ± 0.021	0.624ProTrp: 0.624 ± 0.008	1.335ProTyr: 1.335 ± 0.014	0.0ProXaa: 0.0 ± 0.0
Gln	2.286GlnAla: 2.286 ± 0.016	0.562GlnCys: 0.562 ± 0.009	1.346GlnAsp: 1.346 ± 0.013	2.116GlnGlu: 2.116 ± 0.019	1.242GlnPhe: 1.242 ± 0.012	1.86GlnGly: 1.86 ± 0.016	0.847GlnHis: 0.847 ± 0.011	1.797GlnIle: 1.797 ± 0.015	1.993GlnLys: 1.993 ± 0.015	3.48GlnLeu: 3.48 ± 0.026	0.876GlnMet: 0.876 ± 0.01	1.434GlnAsn: 1.434 ± 0.016	1.601GlnPro: 1.601 ± 0.018	1.948GlnGln: 1.948 ± 0.031	2.087GlnArg: 2.087 ± 0.016	2.492GlnSer: 2.492 ± 0.019	1.419GlnThr: 1.419 ± 0.015	2.025GlnVal: 2.025 ± 0.016	0.432GlnTrp: 0.432 ± 0.008	0.879GlnTyr: 0.879 ± 0.011	0.0GlnXaa: 0.0 ± 0.0
Arg	4.655ArgAla: 4.655 ± 0.023	1.147ArgCys: 1.147 ± 0.015	2.962ArgAsp: 2.962 ± 0.02	3.882ArgGlu: 3.882 ± 0.025	2.358ArgPhe: 2.358 ± 0.017	4.087ArgGly: 4.087 ± 0.027	1.461ArgHis: 1.461 ± 0.013	3.022ArgIle: 3.022 ± 0.018	3.608ArgLys: 3.608 ± 0.021	5.823ArgLeu: 5.823 ± 0.031	1.418ArgMet: 1.418 ± 0.012	2.335ArgAsn: 2.335 ± 0.016	3.081ArgPro: 3.081 ± 0.023	1.796ArgGln: 1.796 ± 0.015	5.976ArgArg: 5.976 ± 0.041	5.256ArgSer: 5.256 ± 0.03	2.614ArgThr: 2.614 ± 0.019	3.735ArgVal: 3.735 ± 0.022	0.914ArgTrp: 0.914 ± 0.01	1.511ArgTyr: 1.511 ± 0.014	0.0ArgXaa: 0.0 ± 0.0
Ser	6.632SerAla: 6.632 ± 0.029	1.671SerCys: 1.671 ± 0.015	4.177SerAsp: 4.177 ± 0.024	4.519SerGlu: 4.519 ± 0.028	3.724SerPhe: 3.724 ± 0.022	5.945SerGly: 5.945 ± 0.03	1.861SerHis: 1.861 ± 0.016	4.13SerIle: 4.13 ± 0.027	4.229SerLys: 4.229 ± 0.024	8.76SerLeu: 8.76 ± 0.047	1.913SerMet: 1.913 ± 0.016	3.559SerAsn: 3.559 ± 0.029	5.157SerPro: 5.157 ± 0.035	2.556SerGln: 2.556 ± 0.019	4.719SerArg: 4.719 ± 0.026	11.6SerSer: 11.6 ± 0.064	4.41SerThr: 4.41 ± 0.028	4.888SerVal: 4.888 ± 0.023	1.182SerTrp: 1.182 ± 0.012	2.218SerTyr: 2.218 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	3.893ThrAla: 3.893 ± 0.025	0.88ThrCys: 0.88 ± 0.01	2.098ThrAsp: 2.098 ± 0.017	2.477ThrGlu: 2.477 ± 0.021	1.874ThrPhe: 1.874 ± 0.016	3.152ThrGly: 3.152 ± 0.021	0.953ThrHis: 0.953 ± 0.01	2.473ThrIle: 2.473 ± 0.017	2.347ThrLys: 2.347 ± 0.019	4.497ThrLeu: 4.497 ± 0.024	1.067ThrMet: 1.067 ± 0.011	1.872ThrAsn: 1.872 ± 0.017	2.546ThrPro: 2.546 ± 0.022	1.285ThrGln: 1.285 ± 0.013	2.314ThrArg: 2.314 ± 0.016	4.139ThrSer: 4.139 ± 0.024	2.869ThrThr: 2.869 ± 0.025	3.227ThrVal: 3.227 ± 0.02	0.614ThrTrp: 0.614 ± 0.009	1.313ThrTyr: 1.313 ± 0.013	0.0ThrXaa: 0.0 ± 0.0
Val	5.784ValAla: 5.784 ± 0.031	1.08ValCys: 1.08 ± 0.01	3.719ValAsp: 3.719 ± 0.023	4.357ValGlu: 4.357 ± 0.025	2.548ValPhe: 2.548 ± 0.02	4.55ValGly: 4.55 ± 0.023	1.471ValHis: 1.471 ± 0.013	3.119ValIle: 3.119 ± 0.02	3.309ValLys: 3.309 ± 0.023	6.416ValLeu: 6.416 ± 0.027	1.407ValMet: 1.407 ± 0.012	2.232ValAsn: 2.232 ± 0.017	3.303ValPro: 3.303 ± 0.02	2.023ValGln: 2.023 ± 0.015	3.708ValArg: 3.708 ± 0.022	4.966ValSer: 4.966 ± 0.025	2.976ValThr: 2.976 ± 0.019	5.234ValVal: 5.234 ± 0.034	0.782ValTrp: 0.782 ± 0.01	1.804ValTyr: 1.804 ± 0.015	0.0ValXaa: 0.0 ± 0.0
Trp	0.961TrpAla: 0.961 ± 0.011	0.24TrpCys: 0.24 ± 0.006	0.688TrpAsp: 0.688 ± 0.01	0.735TrpGlu: 0.735 ± 0.009	0.506TrpPhe: 0.506 ± 0.006	0.789TrpGly: 0.789 ± 0.01	0.277TrpHis: 0.277 ± 0.006	0.691TrpIle: 0.691 ± 0.009	0.788TrpLys: 0.788 ± 0.01	1.275TrpLeu: 1.275 ± 0.014	0.332TrpMet: 0.332 ± 0.006	0.659TrpAsn: 0.659 ± 0.01	0.524TrpPro: 0.524 ± 0.008	0.417TrpGln: 0.417 ± 0.007	0.976TrpArg: 0.976 ± 0.01	0.99TrpSer: 0.99 ± 0.012	0.627TrpThr: 0.627 ± 0.008	0.801TrpVal: 0.801 ± 0.009	0.252TrpTrp: 0.252 ± 0.006	0.326TrpTyr: 0.326 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.004TyrAla: 2.004 ± 0.019	0.602TyrCys: 0.602 ± 0.008	1.478TyrAsp: 1.478 ± 0.014	1.515TyrGlu: 1.515 ± 0.015	1.193TyrPhe: 1.193 ± 0.012	2.065TyrGly: 2.065 ± 0.017	0.655TyrHis: 0.655 ± 0.01	1.377TyrIle: 1.377 ± 0.014	1.361TyrLys: 1.361 ± 0.014	2.736TyrLeu: 2.736 ± 0.023	0.657TyrMet: 0.657 ± 0.008	1.222TyrAsn: 1.222 ± 0.014	1.198TyrPro: 1.198 ± 0.011	0.824TyrGln: 0.824 ± 0.01	1.509TyrArg: 1.509 ± 0.015	2.15TyrSer: 2.15 ± 0.017	1.231TyrThr: 1.231 ± 0.015	1.758TyrVal: 1.758 ± 0.015	0.407TyrTrp: 0.407 ± 0.007	0.967TyrTyr: 0.967 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 23408 proteins (9336427 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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