Amino acid dipepetide frequency for Flavivirga rizhaonensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.602AlaAla: 3.602 ± 0.075	0.552AlaCys: 0.552 ± 0.022	2.958AlaAsp: 2.958 ± 0.059	3.328AlaGlu: 3.328 ± 0.058	3.199AlaPhe: 3.199 ± 0.05	3.678AlaGly: 3.678 ± 0.069	1.012AlaHis: 1.012 ± 0.027	5.319AlaIle: 5.319 ± 0.067	4.36AlaLys: 4.36 ± 0.07	5.811AlaLeu: 5.811 ± 0.076	1.315AlaMet: 1.315 ± 0.031	3.442AlaAsn: 3.442 ± 0.055	1.8AlaPro: 1.8 ± 0.045	1.978AlaGln: 1.978 ± 0.043	1.781AlaArg: 1.781 ± 0.045	4.154AlaSer: 4.154 ± 0.056	3.398AlaThr: 3.398 ± 0.061	3.548AlaVal: 3.548 ± 0.057	0.589AlaTrp: 0.589 ± 0.019	2.465AlaTyr: 2.465 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.428CysAla: 0.428 ± 0.02	0.098CysCys: 0.098 ± 0.008	0.474CysAsp: 0.474 ± 0.028	0.488CysGlu: 0.488 ± 0.02	0.471CysPhe: 0.471 ± 0.019	0.576CysGly: 0.576 ± 0.024	0.204CysHis: 0.204 ± 0.017	0.656CysIle: 0.656 ± 0.025	0.556CysLys: 0.556 ± 0.021	0.665CysLeu: 0.665 ± 0.021	0.159CysMet: 0.159 ± 0.011	0.439CysAsn: 0.439 ± 0.019	0.313CysPro: 0.313 ± 0.017	0.192CysGln: 0.192 ± 0.013	0.204CysArg: 0.204 ± 0.013	0.609CysSer: 0.609 ± 0.025	0.424CysThr: 0.424 ± 0.025	0.438CysVal: 0.438 ± 0.019	0.07CysTrp: 0.07 ± 0.008	0.32CysTyr: 0.32 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.59AspAla: 3.59 ± 0.053	0.435AspCys: 0.435 ± 0.023	3.196AspAsp: 3.196 ± 0.055	3.55AspGlu: 3.55 ± 0.054	3.711AspPhe: 3.711 ± 0.061	3.725AspGly: 3.725 ± 0.075	0.918AspHis: 0.918 ± 0.024	5.167AspIle: 5.167 ± 0.063	4.258AspLys: 4.258 ± 0.066	5.316AspLeu: 5.316 ± 0.068	1.163AspMet: 1.163 ± 0.031	3.53AspAsn: 3.53 ± 0.055	1.646AspPro: 1.646 ± 0.044	1.333AspGln: 1.333 ± 0.034	1.777AspArg: 1.777 ± 0.036	3.362AspSer: 3.362 ± 0.058	3.048AspThr: 3.048 ± 0.055	3.779AspVal: 3.779 ± 0.051	0.769AspTrp: 0.769 ± 0.024	3.051AspTyr: 3.051 ± 0.054	0.0AspXaa: 0.0 ± 0.0
Glu	4.308GluAla: 4.308 ± 0.072	0.353GluCys: 0.353 ± 0.018	3.701GluAsp: 3.701 ± 0.056	4.273GluGlu: 4.273 ± 0.067	2.939GluPhe: 2.939 ± 0.05	3.555GluGly: 3.555 ± 0.046	1.145GluHis: 1.145 ± 0.028	5.239GluIle: 5.239 ± 0.067	5.47GluLys: 5.47 ± 0.077	5.971GluLeu: 5.971 ± 0.079	1.293GluMet: 1.293 ± 0.033	4.653GluAsn: 4.653 ± 0.068	1.542GluPro: 1.542 ± 0.039	1.997GluGln: 1.997 ± 0.037	2.338GluArg: 2.338 ± 0.045	3.555GluSer: 3.555 ± 0.054	3.843GluThr: 3.843 ± 0.052	4.034GluVal: 4.034 ± 0.06	0.633GluTrp: 0.633 ± 0.024	2.258GluTyr: 2.258 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	2.661PheAla: 2.661 ± 0.041	0.476PheCys: 0.476 ± 0.021	3.231PheAsp: 3.231 ± 0.056	3.37PheGlu: 3.37 ± 0.054	2.785PhePhe: 2.785 ± 0.05	3.439PheGly: 3.439 ± 0.052	0.847PheHis: 0.847 ± 0.025	4.194PheIle: 4.194 ± 0.064	4.365PheLys: 4.365 ± 0.062	4.575PheLeu: 4.575 ± 0.066	1.034PheMet: 1.034 ± 0.026	3.98PheAsn: 3.98 ± 0.063	1.677PhePro: 1.677 ± 0.034	1.459PheGln: 1.459 ± 0.033	1.587PheArg: 1.587 ± 0.035	4.174PheSer: 4.174 ± 0.061	3.073PheThr: 3.073 ± 0.049	2.893PheVal: 2.893 ± 0.048	0.582PheTrp: 0.582 ± 0.02	2.16PheTyr: 2.16 ± 0.043	0.0PheXaa: 0.0 ± 0.0
Gly	3.874GlyAla: 3.874 ± 0.061	0.639GlyCys: 0.639 ± 0.033	3.495GlyAsp: 3.495 ± 0.059	3.435GlyGlu: 3.435 ± 0.058	3.651GlyPhe: 3.651 ± 0.059	4.407GlyGly: 4.407 ± 0.092	1.171GlyHis: 1.171 ± 0.032	5.293GlyIle: 5.293 ± 0.072	4.822GlyLys: 4.822 ± 0.071	5.68GlyLeu: 5.68 ± 0.081	1.395GlyMet: 1.395 ± 0.03	3.885GlyAsn: 3.885 ± 0.075	1.303GlyPro: 1.303 ± 0.041	1.758GlyGln: 1.758 ± 0.042	2.04GlyArg: 2.04 ± 0.044	3.954GlySer: 3.954 ± 0.07	3.994GlyThr: 3.994 ± 0.088	4.229GlyVal: 4.229 ± 0.068	0.769GlyTrp: 0.769 ± 0.025	2.865GlyTyr: 2.865 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	0.947HisAla: 0.947 ± 0.026	0.167HisCys: 0.167 ± 0.011	0.936HisAsp: 0.936 ± 0.028	0.933HisGlu: 0.933 ± 0.027	1.147HisPhe: 1.147 ± 0.029	1.097HisGly: 1.097 ± 0.03	0.493HisHis: 0.493 ± 0.024	1.602HisIle: 1.602 ± 0.039	1.293HisLys: 1.293 ± 0.036	1.792HisLeu: 1.792 ± 0.042	0.308HisMet: 0.308 ± 0.015	1.034HisAsn: 1.034 ± 0.027	0.823HisPro: 0.823 ± 0.022	0.642HisGln: 0.642 ± 0.024	0.622HisArg: 0.622 ± 0.022	1.044HisSer: 1.044 ± 0.028	0.96HisThr: 0.96 ± 0.029	1.034HisVal: 1.034 ± 0.027	0.249HisTrp: 0.249 ± 0.014	0.876HisTyr: 0.876 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.182IleAla: 5.182 ± 0.072	0.637IleCys: 0.637 ± 0.02	5.48IleAsp: 5.48 ± 0.065	5.815IleGlu: 5.815 ± 0.074	3.647IlePhe: 3.647 ± 0.054	5.213IleGly: 5.213 ± 0.079	1.368IleHis: 1.368 ± 0.032	6.875IleIle: 6.875 ± 0.098	6.867IleLys: 6.867 ± 0.083	7.29IleLeu: 7.29 ± 0.096	1.459IleMet: 1.459 ± 0.037	5.62IleAsn: 5.62 ± 0.073	3.269IlePro: 3.269 ± 0.06	2.497IleGln: 2.497 ± 0.045	2.542IleArg: 2.542 ± 0.037	6.102IleSer: 6.102 ± 0.064	5.166IleThr: 5.166 ± 0.074	4.906IleVal: 4.906 ± 0.071	0.729IleTrp: 0.729 ± 0.025	3.105IleTyr: 3.105 ± 0.054	0.0IleXaa: 0.0 ± 0.0
Lys	4.838LysAla: 4.838 ± 0.062	0.374LysCys: 0.374 ± 0.018	4.926LysAsp: 4.926 ± 0.058	6.222LysGlu: 6.222 ± 0.087	3.037LysPhe: 3.037 ± 0.054	4.708LysGly: 4.708 ± 0.057	1.665LysHis: 1.665 ± 0.041	6.525LysIle: 6.525 ± 0.078	7.429LysLys: 7.429 ± 0.096	6.956LysLeu: 6.956 ± 0.077	1.883LysMet: 1.883 ± 0.04	5.846LysAsn: 5.846 ± 0.081	2.59LysPro: 2.59 ± 0.049	2.911LysGln: 2.911 ± 0.056	3.191LysArg: 3.191 ± 0.057	4.961LysSer: 4.961 ± 0.064	5.14LysThr: 5.14 ± 0.065	4.638LysVal: 4.638 ± 0.057	0.85LysTrp: 0.85 ± 0.024	3.266LysTyr: 3.266 ± 0.056	0.0LysXaa: 0.0 ± 0.0
Leu	5.088LeuAla: 5.088 ± 0.077	0.693LeuCys: 0.693 ± 0.026	5.1LeuAsp: 5.1 ± 0.063	6.041LeuGlu: 6.041 ± 0.07	5.018LeuPhe: 5.018 ± 0.069	5.638LeuGly: 5.638 ± 0.08	1.485LeuHis: 1.485 ± 0.038	7.304LeuIle: 7.304 ± 0.094	8.387LeuLys: 8.387 ± 0.096	8.557LeuLeu: 8.557 ± 0.101	1.88LeuMet: 1.88 ± 0.047	6.262LeuAsn: 6.262 ± 0.073	3.32LeuPro: 3.32 ± 0.053	2.842LeuGln: 2.842 ± 0.052	2.968LeuArg: 2.968 ± 0.049	6.829LeuSer: 6.829 ± 0.08	4.953LeuThr: 4.953 ± 0.07	5.171LeuVal: 5.171 ± 0.071	0.822LeuTrp: 0.822 ± 0.025	3.322LeuTyr: 3.322 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	1.371MetAla: 1.371 ± 0.037	0.15MetCys: 0.15 ± 0.011	1.001MetAsp: 1.001 ± 0.029	1.135MetGlu: 1.135 ± 0.03	0.871MetPhe: 0.871 ± 0.03	1.253MetGly: 1.253 ± 0.031	0.418MetHis: 0.418 ± 0.017	1.475MetIle: 1.475 ± 0.036	2.066MetLys: 2.066 ± 0.043	1.78MetLeu: 1.78 ± 0.035	0.49MetMet: 0.49 ± 0.02	1.236MetAsn: 1.236 ± 0.029	0.77MetPro: 0.77 ± 0.027	0.707MetGln: 0.707 ± 0.023	0.716MetArg: 0.716 ± 0.023	1.402MetSer: 1.402 ± 0.032	1.102MetThr: 1.102 ± 0.031	1.221MetVal: 1.221 ± 0.03	0.158MetTrp: 0.158 ± 0.011	0.731MetTyr: 0.731 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.761AsnAla: 3.761 ± 0.055	0.495AsnCys: 0.495 ± 0.02	3.874AsnAsp: 3.874 ± 0.05	3.954AsnGlu: 3.954 ± 0.058	3.174AsnPhe: 3.174 ± 0.055	4.335AsnGly: 4.335 ± 0.07	1.175AsnHis: 1.175 ± 0.027	5.766AsnIle: 5.766 ± 0.074	5.384AsnLys: 5.384 ± 0.071	5.766AsnLeu: 5.766 ± 0.079	1.334AsnMet: 1.334 ± 0.033	4.955AsnAsn: 4.955 ± 0.091	2.738AsnPro: 2.738 ± 0.054	2.255AsnGln: 2.255 ± 0.048	2.314AsnArg: 2.314 ± 0.042	4.301AsnSer: 4.301 ± 0.069	4.274AsnThr: 4.274 ± 0.079	3.684AsnVal: 3.684 ± 0.063	0.843AsnTrp: 0.843 ± 0.023	3.153AsnTyr: 3.153 ± 0.055	0.0AsnXaa: 0.0 ± 0.0
Pro	1.677ProAla: 1.677 ± 0.047	0.239ProCys: 0.239 ± 0.013	2.001ProAsp: 2.001 ± 0.036	2.645ProGlu: 2.645 ± 0.052	1.855ProPhe: 1.855 ± 0.032	1.796ProGly: 1.796 ± 0.048	0.613ProHis: 0.613 ± 0.018	2.805ProIle: 2.805 ± 0.049	2.64ProLys: 2.64 ± 0.044	2.862ProLeu: 2.862 ± 0.049	0.618ProMet: 0.618 ± 0.022	2.455ProAsn: 2.455 ± 0.047	0.808ProPro: 0.808 ± 0.032	1.01ProGln: 1.01 ± 0.027	0.922ProArg: 0.922 ± 0.026	2.143ProSer: 2.143 ± 0.046	1.914ProThr: 1.914 ± 0.049	2.14ProVal: 2.14 ± 0.046	0.369ProTrp: 0.369 ± 0.017	1.38ProTyr: 1.38 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	1.777GlnAla: 1.777 ± 0.037	0.176GlnCys: 0.176 ± 0.012	1.657GlnAsp: 1.657 ± 0.035	2.101GlnGlu: 2.101 ± 0.048	1.588GlnPhe: 1.588 ± 0.037	1.721GlnGly: 1.721 ± 0.038	0.545GlnHis: 0.545 ± 0.02	2.593GlnIle: 2.593 ± 0.041	2.556GlnLys: 2.556 ± 0.05	3.21GlnLeu: 3.21 ± 0.05	0.659GlnMet: 0.659 ± 0.02	2.129GlnAsn: 2.129 ± 0.04	0.993GlnPro: 0.993 ± 0.028	1.204GlnGln: 1.204 ± 0.037	1.09GlnArg: 1.09 ± 0.029	1.832GlnSer: 1.832 ± 0.033	1.811GlnThr: 1.811 ± 0.039	1.792GlnVal: 1.792 ± 0.044	0.344GlnTrp: 0.344 ± 0.018	1.265GlnTyr: 1.265 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	2.005ArgAla: 2.005 ± 0.046	0.2ArgCys: 0.2 ± 0.013	1.813ArgAsp: 1.813 ± 0.038	1.936ArgGlu: 1.936 ± 0.044	1.909ArgPhe: 1.909 ± 0.038	1.992ArgGly: 1.992 ± 0.044	0.63ArgHis: 0.63 ± 0.02	2.826ArgIle: 2.826 ± 0.041	2.698ArgLys: 2.698 ± 0.051	3.198ArgLeu: 3.198 ± 0.05	0.729ArgMet: 0.729 ± 0.023	2.095ArgAsn: 2.095 ± 0.039	1.05ArgPro: 1.05 ± 0.026	1.031ArgGln: 1.031 ± 0.029	1.297ArgArg: 1.297 ± 0.034	1.907ArgSer: 1.907 ± 0.043	1.733ArgThr: 1.733 ± 0.04	2.07ArgVal: 2.07 ± 0.041	0.415ArgTrp: 0.415 ± 0.015	1.501ArgTyr: 1.501 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	3.432SerAla: 3.432 ± 0.054	0.686SerCys: 0.686 ± 0.021	3.673SerAsp: 3.673 ± 0.061	4.013SerGlu: 4.013 ± 0.061	3.927SerPhe: 3.927 ± 0.054	4.693SerGly: 4.693 ± 0.075	1.204SerHis: 1.204 ± 0.029	5.959SerIle: 5.959 ± 0.069	5.579SerLys: 5.579 ± 0.068	6.033SerLeu: 6.033 ± 0.077	1.206SerMet: 1.206 ± 0.033	4.541SerAsn: 4.541 ± 0.068	2.084SerPro: 2.084 ± 0.046	2.091SerGln: 2.091 ± 0.041	2.131SerArg: 2.131 ± 0.046	4.556SerSer: 4.556 ± 0.075	3.678SerThr: 3.678 ± 0.068	3.942SerVal: 3.942 ± 0.053	0.736SerTrp: 0.736 ± 0.023	2.843SerTyr: 2.843 ± 0.054	0.0SerXaa: 0.0 ± 0.0
Thr	3.325ThrAla: 3.325 ± 0.074	0.412ThrCys: 0.412 ± 0.021	3.338ThrAsp: 3.338 ± 0.066	3.222ThrGlu: 3.222 ± 0.049	3.145ThrPhe: 3.145 ± 0.055	3.932ThrGly: 3.932 ± 0.083	1.055ThrHis: 1.055 ± 0.03	5.418ThrIle: 5.418 ± 0.075	4.171ThrLys: 4.171 ± 0.055	5.529ThrLeu: 5.529 ± 0.068	0.945ThrMet: 0.945 ± 0.025	3.779ThrAsn: 3.779 ± 0.072	2.46ThrPro: 2.46 ± 0.055	1.779ThrGln: 1.779 ± 0.039	1.639ThrArg: 1.639 ± 0.036	4.154ThrSer: 4.154 ± 0.069	3.678ThrThr: 3.678 ± 0.074	3.661ThrVal: 3.661 ± 0.069	0.589ThrTrp: 0.589 ± 0.025	2.581ThrTyr: 2.581 ± 0.052	0.0ThrXaa: 0.0 ± 0.0
Val	3.561ValAla: 3.561 ± 0.059	0.521ValCys: 0.521 ± 0.022	3.452ValAsp: 3.452 ± 0.055	3.658ValGlu: 3.658 ± 0.059	3.434ValPhe: 3.434 ± 0.055	3.546ValGly: 3.546 ± 0.06	0.951ValHis: 0.951 ± 0.025	4.998ValIle: 4.998 ± 0.068	4.501ValLys: 4.501 ± 0.062	5.817ValLeu: 5.817 ± 0.07	1.175ValMet: 1.175 ± 0.029	3.784ValAsn: 3.784 ± 0.056	1.983ValPro: 1.983 ± 0.039	1.551ValGln: 1.551 ± 0.033	1.851ValArg: 1.851 ± 0.041	4.561ValSer: 4.561 ± 0.056	3.561ValThr: 3.561 ± 0.075	3.678ValVal: 3.678 ± 0.062	0.645ValTrp: 0.645 ± 0.024	2.444ValTyr: 2.444 ± 0.049	0.0ValXaa: 0.0 ± 0.0
Trp	0.566TrpAla: 0.566 ± 0.021	0.126TrpCys: 0.126 ± 0.009	0.649TrpAsp: 0.649 ± 0.022	0.668TrpGlu: 0.668 ± 0.021	0.589TrpPhe: 0.589 ± 0.023	0.734TrpGly: 0.734 ± 0.028	0.252TrpHis: 0.252 ± 0.014	0.748TrpIle: 0.748 ± 0.028	0.875TrpLys: 0.875 ± 0.028	0.988TrpLeu: 0.988 ± 0.026	0.279TrpMet: 0.279 ± 0.016	0.774TrpAsn: 0.774 ± 0.028	0.245TrpPro: 0.245 ± 0.014	0.419TrpGln: 0.419 ± 0.018	0.396TrpArg: 0.396 ± 0.018	0.653TrpSer: 0.653 ± 0.022	0.585TrpThr: 0.585 ± 0.025	0.663TrpVal: 0.663 ± 0.023	0.157TrpTrp: 0.157 ± 0.01	0.467TrpTyr: 0.467 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.298TyrAla: 2.298 ± 0.038	0.353TyrCys: 0.353 ± 0.016	2.371TyrAsp: 2.371 ± 0.049	2.312TyrGlu: 2.312 ± 0.044	2.468TyrPhe: 2.468 ± 0.047	2.62TyrGly: 2.62 ± 0.051	0.849TyrHis: 0.849 ± 0.024	3.007TyrIle: 3.007 ± 0.049	3.677TyrLys: 3.677 ± 0.06	3.885TyrLeu: 3.885 ± 0.061	0.731TyrMet: 0.731 ± 0.022	3.096TyrAsn: 3.096 ± 0.053	1.476TyrPro: 1.476 ± 0.034	1.389TyrGln: 1.389 ± 0.035	1.628TyrArg: 1.628 ± 0.037	2.754TyrSer: 2.754 ± 0.055	2.477TyrThr: 2.477 ± 0.054	2.152TyrVal: 2.152 ± 0.039	0.512TyrTrp: 0.512 ± 0.022	1.95TyrTyr: 1.95 ± 0.042	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4045 proteins (1423285 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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