Amino acid dipepetide frequency for Wenzhou weivirus-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.777AlaAla: 12.777 ± 3.643
0.852AlaCys: 0.852 ± 0.456
1.704AlaAsp: 1.704 ± 0.913
4.259AlaGlu: 4.259 ± 0.68
1.704AlaPhe: 1.704 ± 0.689
9.37AlaGly: 9.37 ± 1.387
0.852AlaHis: 0.852 ± 1.146
3.407AlaIle: 3.407 ± 1.826
4.259AlaLys: 4.259 ± 0.68
7.666AlaLeu: 7.666 ± 2.506
4.259AlaMet: 4.259 ± 0.68
5.111AlaAsn: 5.111 ± 0.465
10.221AlaPro: 10.221 ± 0.671
2.555AlaGln: 2.555 ± 1.835
7.666AlaArg: 7.666 ± 2.3
4.259AlaSer: 4.259 ± 0.68
8.518AlaThr: 8.518 ± 0.242
7.666AlaVal: 7.666 ± 0.698
1.704AlaTrp: 1.704 ± 0.913
1.704AlaTyr: 1.704 ± 0.689
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.852CysAsp: 0.852 ± 0.456
0.852CysGlu: 0.852 ± 0.456
1.704CysPhe: 1.704 ± 0.913
1.704CysGly: 1.704 ± 0.913
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.852CysLeu: 0.852 ± 0.456
0.852CysMet: 0.852 ± 0.456
0.0CysAsn: 0.0 ± 0.0
0.852CysPro: 0.852 ± 0.456
1.704CysGln: 1.704 ± 0.913
1.704CysArg: 1.704 ± 0.689
1.704CysSer: 1.704 ± 0.913
1.704CysThr: 1.704 ± 0.913
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.259AspAla: 4.259 ± 2.524
0.0AspCys: 0.0 ± 0.0
1.704AspAsp: 1.704 ± 0.913
2.555AspGlu: 2.555 ± 1.369
0.852AspPhe: 0.852 ± 0.456
5.111AspGly: 5.111 ± 0.465
0.852AspHis: 0.852 ± 0.456
1.704AspIle: 1.704 ± 0.689
1.704AspLys: 1.704 ± 0.913
4.259AspLeu: 4.259 ± 2.282
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
3.407AspPro: 3.407 ± 0.224
0.852AspGln: 0.852 ± 1.146
2.555AspArg: 2.555 ± 1.369
2.555AspSer: 2.555 ± 0.233
2.555AspThr: 2.555 ± 1.835
2.555AspVal: 2.555 ± 0.233
0.852AspTrp: 0.852 ± 1.146
0.852AspTyr: 0.852 ± 0.456
0.0AspXaa: 0.0 ± 0.0
Glu
2.555GluAla: 2.555 ± 1.369
2.555GluCys: 2.555 ± 1.369
3.407GluAsp: 3.407 ± 0.224
6.814GluGlu: 6.814 ± 2.05
3.407GluPhe: 3.407 ± 1.378
4.259GluGly: 4.259 ± 2.282
1.704GluHis: 1.704 ± 0.913
0.0GluIle: 0.0 ± 0.0
4.259GluLys: 4.259 ± 0.68
4.259GluLeu: 4.259 ± 0.68
2.555GluMet: 2.555 ± 1.62
5.963GluAsn: 5.963 ± 0.009
2.555GluPro: 2.555 ± 0.233
2.555GluGln: 2.555 ± 0.233
7.666GluArg: 7.666 ± 4.108
4.259GluSer: 4.259 ± 2.524
0.852GluThr: 0.852 ± 0.456
2.555GluVal: 2.555 ± 0.233
1.704GluTrp: 1.704 ± 0.913
1.704GluTyr: 1.704 ± 0.913
0.0GluXaa: 0.0 ± 0.0
Phe
1.704PheAla: 1.704 ± 0.689
0.852PheCys: 0.852 ± 0.456
2.555PheAsp: 2.555 ± 0.233
2.555PheGlu: 2.555 ± 1.369
0.852PhePhe: 0.852 ± 0.456
3.407PheGly: 3.407 ± 0.224
0.852PheHis: 0.852 ± 0.456
0.852PheIle: 0.852 ± 1.146
3.407PheLys: 3.407 ± 1.826
2.555PheLeu: 2.555 ± 1.835
1.704PheMet: 1.704 ± 0.689
2.555PheAsn: 2.555 ± 0.233
0.0PhePro: 0.0 ± 0.0
1.704PheGln: 1.704 ± 0.689
4.259PheArg: 4.259 ± 0.68
6.814PheSer: 6.814 ± 2.756
2.555PheThr: 2.555 ± 1.369
0.852PheVal: 0.852 ± 1.146
0.852PheTrp: 0.852 ± 0.456
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
9.37GlyAla: 9.37 ± 1.817
0.0GlyCys: 0.0 ± 0.0
3.407GlyAsp: 3.407 ± 0.224
3.407GlyGlu: 3.407 ± 0.224
5.963GlyPhe: 5.963 ± 0.009
5.111GlyGly: 5.111 ± 0.465
4.259GlyHis: 4.259 ± 2.524
4.259GlyIle: 4.259 ± 2.282
3.407GlyLys: 3.407 ± 0.224
1.704GlyLeu: 1.704 ± 2.291
1.704GlyMet: 1.704 ± 2.291
0.852GlyAsn: 0.852 ± 1.146
7.666GlyPro: 7.666 ± 0.698
3.407GlyGln: 3.407 ± 0.224
5.111GlyArg: 5.111 ± 5.271
5.111GlySer: 5.111 ± 3.669
5.963GlyThr: 5.963 ± 1.593
6.814GlyVal: 6.814 ± 3.652
1.704GlyTrp: 1.704 ± 0.689
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.704HisAla: 1.704 ± 0.689
0.0HisCys: 0.0 ± 0.0
0.852HisAsp: 0.852 ± 0.456
1.704HisGlu: 1.704 ± 0.913
1.704HisPhe: 1.704 ± 0.913
2.555HisGly: 2.555 ± 0.233
1.704HisHis: 1.704 ± 0.689
2.555HisIle: 2.555 ± 1.369
0.0HisLys: 0.0 ± 0.0
3.407HisLeu: 3.407 ± 1.826
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.704HisPro: 1.704 ± 0.689
1.704HisGln: 1.704 ± 0.689
0.852HisArg: 0.852 ± 0.456
1.704HisSer: 1.704 ± 0.689
0.0HisThr: 0.0 ± 0.0
1.704HisVal: 1.704 ± 0.689
0.0HisTrp: 0.0 ± 0.0
1.704HisTyr: 1.704 ± 2.291
0.0HisXaa: 0.0 ± 0.0
Ile
1.704IleAla: 1.704 ± 0.913
0.0IleCys: 0.0 ± 0.0
3.407IleAsp: 3.407 ± 2.98
2.555IleGlu: 2.555 ± 0.233
2.555IlePhe: 2.555 ± 1.369
0.0IleGly: 0.0 ± 0.0
0.0IleHis: 0.0 ± 0.0
0.852IleIle: 0.852 ± 0.456
4.259IleLys: 4.259 ± 2.282
3.407IleLeu: 3.407 ± 1.826
0.852IleMet: 0.852 ± 0.456
2.555IleAsn: 2.555 ± 0.233
1.704IlePro: 1.704 ± 0.689
1.704IleGln: 1.704 ± 0.913
2.555IleArg: 2.555 ± 1.369
3.407IleSer: 3.407 ± 1.378
1.704IleThr: 1.704 ± 0.913
1.704IleVal: 1.704 ± 0.913
0.852IleTrp: 0.852 ± 0.456
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
7.666LysAla: 7.666 ± 0.698
0.852LysCys: 0.852 ± 0.456
3.407LysAsp: 3.407 ± 1.826
4.259LysGlu: 4.259 ± 2.282
2.555LysPhe: 2.555 ± 1.835
2.555LysGly: 2.555 ± 1.369
3.407LysHis: 3.407 ± 1.826
1.704LysIle: 1.704 ± 0.913
4.259LysLys: 4.259 ± 0.68
3.407LysLeu: 3.407 ± 1.826
1.704LysMet: 1.704 ± 0.913
0.852LysAsn: 0.852 ± 0.456
3.407LysPro: 3.407 ± 0.224
0.852LysGln: 0.852 ± 1.146
2.555LysArg: 2.555 ± 1.835
3.407LysSer: 3.407 ± 0.224
3.407LysThr: 3.407 ± 0.224
2.555LysVal: 2.555 ± 1.369
0.852LysTrp: 0.852 ± 0.456
1.704LysTyr: 1.704 ± 0.913
0.0LysXaa: 0.0 ± 0.0
Leu
5.963LeuAla: 5.963 ± 1.593
1.704LeuCys: 1.704 ± 0.913
1.704LeuAsp: 1.704 ± 0.913
5.111LeuGlu: 5.111 ± 1.137
3.407LeuPhe: 3.407 ± 0.224
6.814LeuGly: 6.814 ± 1.154
0.0LeuHis: 0.0 ± 0.0
3.407LeuIle: 3.407 ± 0.224
7.666LeuLys: 7.666 ± 0.904
3.407LeuLeu: 3.407 ± 1.378
3.407LeuMet: 3.407 ± 0.852
2.555LeuAsn: 2.555 ± 1.835
5.963LeuPro: 5.963 ± 3.195
0.852LeuGln: 0.852 ± 0.456
3.407LeuArg: 3.407 ± 1.378
5.963LeuSer: 5.963 ± 1.593
4.259LeuThr: 4.259 ± 2.282
5.111LeuVal: 5.111 ± 2.739
0.852LeuTrp: 0.852 ± 0.456
2.555LeuTyr: 2.555 ± 0.233
0.0LeuXaa: 0.0 ± 0.0
Met
3.407MetAla: 3.407 ± 1.378
0.852MetCys: 0.852 ± 0.456
1.704MetAsp: 1.704 ± 2.291
5.111MetGlu: 5.111 ± 1.137
0.852MetPhe: 0.852 ± 1.146
0.852MetGly: 0.852 ± 1.146
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.704MetLys: 1.704 ± 0.913
4.259MetLeu: 4.259 ± 2.282
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.704MetPro: 1.704 ± 0.689
0.0MetGln: 0.0 ± 0.0
1.704MetArg: 1.704 ± 0.913
2.555MetSer: 2.555 ± 1.369
2.555MetThr: 2.555 ± 1.369
2.555MetVal: 2.555 ± 1.835
1.704MetTrp: 1.704 ± 0.913
1.704MetTyr: 1.704 ± 2.291
0.0MetXaa: 0.0 ± 0.0
Asn
5.963AsnAla: 5.963 ± 1.611
0.0AsnCys: 0.0 ± 0.0
0.852AsnAsp: 0.852 ± 1.146
1.704AsnGlu: 1.704 ± 0.913
1.704AsnPhe: 1.704 ± 0.913
5.111AsnGly: 5.111 ± 2.067
1.704AsnHis: 1.704 ± 0.689
0.852AsnIle: 0.852 ± 1.146
1.704AsnLys: 1.704 ± 0.913
4.259AsnLeu: 4.259 ± 2.282
2.555AsnMet: 2.555 ± 1.835
0.0AsnAsn: 0.0 ± 0.0
0.852AsnPro: 0.852 ± 0.456
0.0AsnGln: 0.0 ± 0.0
0.0AsnArg: 0.0 ± 0.0
3.407AsnSer: 3.407 ± 1.378
2.555AsnThr: 2.555 ± 1.835
3.407AsnVal: 3.407 ± 2.98
1.704AsnTrp: 1.704 ± 0.689
1.704AsnTyr: 1.704 ± 2.291
0.0AsnXaa: 0.0 ± 0.0
Pro
10.221ProAla: 10.221 ± 2.273
0.852ProCys: 0.852 ± 0.456
1.704ProAsp: 1.704 ± 0.689
5.963ProGlu: 5.963 ± 1.593
0.852ProPhe: 0.852 ± 0.456
5.111ProGly: 5.111 ± 1.137
1.704ProHis: 1.704 ± 0.689
2.555ProIle: 2.555 ± 1.835
1.704ProLys: 1.704 ± 0.689
0.852ProLeu: 0.852 ± 1.146
1.704ProMet: 1.704 ± 0.689
2.555ProAsn: 2.555 ± 1.835
5.963ProPro: 5.963 ± 1.593
0.852ProGln: 0.852 ± 0.456
4.259ProArg: 4.259 ± 2.524
4.259ProSer: 4.259 ± 0.922
3.407ProThr: 3.407 ± 1.378
5.111ProVal: 5.111 ± 1.137
0.0ProTrp: 0.0 ± 0.0
1.704ProTyr: 1.704 ± 0.913
0.0ProXaa: 0.0 ± 0.0
Gln
3.407GlnAla: 3.407 ± 1.826
0.0GlnCys: 0.0 ± 0.0
0.852GlnAsp: 0.852 ± 0.456
1.704GlnGlu: 1.704 ± 0.689
0.852GlnPhe: 0.852 ± 0.456
2.555GlnGly: 2.555 ± 0.233
0.852GlnHis: 0.852 ± 0.456
0.0GlnIle: 0.0 ± 0.0
2.555GlnLys: 2.555 ± 1.369
1.704GlnLeu: 1.704 ± 0.913
1.704GlnMet: 1.704 ± 2.291
0.852GlnAsn: 0.852 ± 0.456
2.555GlnPro: 2.555 ± 1.835
0.0GlnGln: 0.0 ± 0.0
0.852GlnArg: 0.852 ± 0.456
0.0GlnSer: 0.0 ± 0.0
1.704GlnThr: 1.704 ± 2.291
0.852GlnVal: 0.852 ± 1.146
1.704GlnTrp: 1.704 ± 2.291
1.704GlnTyr: 1.704 ± 0.913
0.0GlnXaa: 0.0 ± 0.0
Arg
11.925ArgAla: 11.925 ± 0.018
0.852ArgCys: 0.852 ± 0.456
0.0ArgAsp: 0.0 ± 0.0
5.111ArgGlu: 5.111 ± 2.739
1.704ArgPhe: 1.704 ± 0.913
5.111ArgGly: 5.111 ± 3.669
0.852ArgHis: 0.852 ± 0.456
3.407ArgIle: 3.407 ± 1.826
5.963ArgLys: 5.963 ± 1.611
5.111ArgLeu: 5.111 ± 2.067
1.704ArgMet: 1.704 ± 0.913
6.814ArgAsn: 6.814 ± 2.756
1.704ArgPro: 1.704 ± 2.291
1.704ArgGln: 1.704 ± 0.689
5.111ArgArg: 5.111 ± 2.067
4.259ArgSer: 4.259 ± 0.68
5.111ArgThr: 5.111 ± 2.067
3.407ArgVal: 3.407 ± 0.224
0.852ArgTrp: 0.852 ± 0.456
0.852ArgTyr: 0.852 ± 1.146
0.0ArgXaa: 0.0 ± 0.0
Ser
5.111SerAla: 5.111 ± 1.137
0.852SerCys: 0.852 ± 0.456
5.111SerAsp: 5.111 ± 1.137
3.407SerGlu: 3.407 ± 1.378
2.555SerPhe: 2.555 ± 1.835
6.814SerGly: 6.814 ± 2.756
0.0SerHis: 0.0 ± 0.0
2.555SerIle: 2.555 ± 1.369
4.259SerLys: 4.259 ± 0.68
7.666SerLeu: 7.666 ± 0.698
1.704SerMet: 1.704 ± 2.291
3.407SerAsn: 3.407 ± 0.224
3.407SerPro: 3.407 ± 1.378
1.704SerGln: 1.704 ± 0.689
4.259SerArg: 4.259 ± 2.282
0.852SerSer: 0.852 ± 0.456
1.704SerThr: 1.704 ± 0.689
5.111SerVal: 5.111 ± 2.067
2.555SerTrp: 2.555 ± 1.369
0.852SerTyr: 0.852 ± 0.456
0.0SerXaa: 0.0 ± 0.0
Thr
5.963ThrAla: 5.963 ± 3.213
0.852ThrCys: 0.852 ± 0.456
1.704ThrAsp: 1.704 ± 0.913
2.555ThrGlu: 2.555 ± 1.369
4.259ThrPhe: 4.259 ± 0.922
3.407ThrGly: 3.407 ± 1.826
3.407ThrHis: 3.407 ± 1.378
1.704ThrIle: 1.704 ± 0.689
2.555ThrLys: 2.555 ± 1.369
5.111ThrLeu: 5.111 ± 1.137
2.555ThrMet: 2.555 ± 1.369
1.704ThrAsn: 1.704 ± 2.291
5.111ThrPro: 5.111 ± 1.137
1.704ThrGln: 1.704 ± 0.689
5.111ThrArg: 5.111 ± 5.271
2.555ThrSer: 2.555 ± 0.233
3.407ThrThr: 3.407 ± 1.378
5.111ThrVal: 5.111 ± 2.739
1.704ThrTrp: 1.704 ± 0.913
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
1.704ValAla: 1.704 ± 0.913
0.852ValCys: 0.852 ± 0.456
1.704ValAsp: 1.704 ± 0.689
4.259ValGlu: 4.259 ± 0.922
2.555ValPhe: 2.555 ± 1.835
6.814ValGly: 6.814 ± 2.756
1.704ValHis: 1.704 ± 0.913
4.259ValIle: 4.259 ± 0.68
0.852ValLys: 0.852 ± 0.456
7.666ValLeu: 7.666 ± 0.904
1.704ValMet: 1.704 ± 0.913
2.555ValAsn: 2.555 ± 1.835
1.704ValPro: 1.704 ± 2.291
1.704ValGln: 1.704 ± 0.913
9.37ValArg: 9.37 ± 0.215
4.259ValSer: 4.259 ± 2.282
5.963ValThr: 5.963 ± 1.593
6.814ValVal: 6.814 ± 2.756
0.0ValTrp: 0.0 ± 0.0
2.555ValTyr: 2.555 ± 0.233
0.0ValXaa: 0.0 ± 0.0
Trp
2.555TrpAla: 2.555 ± 0.233
0.0TrpCys: 0.0 ± 0.0
1.704TrpAsp: 1.704 ± 0.913
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.852TrpGly: 0.852 ± 0.456
0.852TrpHis: 0.852 ± 0.456
1.704TrpIle: 1.704 ± 0.913
0.0TrpLys: 0.0 ± 0.0
0.852TrpLeu: 0.852 ± 0.456
1.704TrpMet: 1.704 ± 0.913
1.704TrpAsn: 1.704 ± 0.689
0.852TrpPro: 0.852 ± 0.456
0.0TrpGln: 0.0 ± 0.0
2.555TrpArg: 2.555 ± 0.233
1.704TrpSer: 1.704 ± 0.913
2.555TrpThr: 2.555 ± 1.835
0.852TrpVal: 0.852 ± 0.456
1.704TrpTrp: 1.704 ± 0.913
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.555TyrAla: 2.555 ± 0.233
2.555TyrCys: 2.555 ± 0.233
0.852TyrAsp: 0.852 ± 1.146
2.555TyrGlu: 2.555 ± 1.835
0.852TyrPhe: 0.852 ± 0.456
1.704TyrGly: 1.704 ± 0.689
0.852TyrHis: 0.852 ± 0.456
0.0TyrIle: 0.0 ± 0.0
0.852TyrLys: 0.852 ± 1.146
1.704TyrLeu: 1.704 ± 0.913
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
0.0TyrPro: 0.0 ± 0.0
0.852TyrGln: 0.852 ± 0.456
0.0TyrArg: 0.0 ± 0.0
0.852TyrSer: 0.852 ± 0.456
0.0TyrThr: 0.0 ± 0.0
4.259TyrVal: 4.259 ± 2.524
0.852TyrTrp: 0.852 ± 0.456
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1175 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski