Amino acid dipepetide frequency for Flavimaricola marinus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.371AlaAla: 16.371 ± 0.175	1.095AlaCys: 1.095 ± 0.03	7.192AlaAsp: 7.192 ± 0.08	8.356AlaGlu: 8.356 ± 0.1	4.323AlaPhe: 4.323 ± 0.055	10.318AlaGly: 10.318 ± 0.107	2.311AlaHis: 2.311 ± 0.045	6.163AlaIle: 6.163 ± 0.068	3.817AlaLys: 3.817 ± 0.059	13.37AlaLeu: 13.37 ± 0.136	3.897AlaMet: 3.897 ± 0.055	2.819AlaAsn: 2.819 ± 0.044	5.723AlaPro: 5.723 ± 0.086	4.325AlaGln: 4.325 ± 0.067	8.149AlaArg: 8.149 ± 0.097	5.854AlaSer: 5.854 ± 0.072	6.114AlaThr: 6.114 ± 0.062	8.368AlaVal: 8.368 ± 0.089	1.414AlaTrp: 1.414 ± 0.032	2.555AlaTyr: 2.555 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	1.104CysAla: 1.104 ± 0.032	0.104CysCys: 0.104 ± 0.009	0.65CysAsp: 0.65 ± 0.022	0.441CysGlu: 0.441 ± 0.02	0.333CysPhe: 0.333 ± 0.015	0.953CysGly: 0.953 ± 0.03	0.278CysHis: 0.278 ± 0.014	0.462CysIle: 0.462 ± 0.019	0.214CysLys: 0.214 ± 0.012	0.878CysLeu: 0.878 ± 0.025	0.171CysMet: 0.171 ± 0.01	0.228CysAsn: 0.228 ± 0.013	0.516CysPro: 0.516 ± 0.019	0.253CysGln: 0.253 ± 0.015	0.503CysArg: 0.503 ± 0.018	0.441CysSer: 0.441 ± 0.017	0.461CysThr: 0.461 ± 0.018	0.633CysVal: 0.633 ± 0.02	0.119CysTrp: 0.119 ± 0.009	0.217CysTyr: 0.217 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.464AspAla: 7.464 ± 0.085	0.526AspCys: 0.526 ± 0.02	3.667AspAsp: 3.667 ± 0.093	3.543AspGlu: 3.543 ± 0.057	2.38AspPhe: 2.38 ± 0.041	5.975AspGly: 5.975 ± 0.097	1.378AspHis: 1.378 ± 0.035	3.188AspIle: 3.188 ± 0.05	1.62AspLys: 1.62 ± 0.039	6.565AspLeu: 6.565 ± 0.075	1.752AspMet: 1.752 ± 0.037	1.314AspAsn: 1.314 ± 0.029	3.922AspPro: 3.922 ± 0.059	1.946AspGln: 1.946 ± 0.034	4.353AspArg: 4.353 ± 0.056	2.331AspSer: 2.331 ± 0.044	3.076AspThr: 3.076 ± 0.065	4.458AspVal: 4.458 ± 0.064	1.263AspTrp: 1.263 ± 0.032	1.56AspTyr: 1.56 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	8.397GluAla: 8.397 ± 0.102	0.383GluCys: 0.383 ± 0.016	3.234GluAsp: 3.234 ± 0.052	3.199GluGlu: 3.199 ± 0.067	1.823GluPhe: 1.823 ± 0.033	4.535GluGly: 4.535 ± 0.064	1.127GluHis: 1.127 ± 0.027	3.561GluIle: 3.561 ± 0.044	1.841GluLys: 1.841 ± 0.047	4.909GluLeu: 4.909 ± 0.063	1.895GluMet: 1.895 ± 0.041	1.596GluAsn: 1.596 ± 0.04	2.697GluPro: 2.697 ± 0.055	2.027GluGln: 2.027 ± 0.041	4.015GluArg: 4.015 ± 0.054	2.212GluSer: 2.212 ± 0.044	3.837GluThr: 3.837 ± 0.063	4.401GluVal: 4.401 ± 0.059	0.745GluTrp: 0.745 ± 0.021	1.037GluTyr: 1.037 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	4.55PheAla: 4.55 ± 0.06	0.439PheCys: 0.439 ± 0.016	2.962PheAsp: 2.962 ± 0.044	2.239PheGlu: 2.239 ± 0.042	1.357PhePhe: 1.357 ± 0.036	3.809PheGly: 3.809 ± 0.06	0.733PheHis: 0.733 ± 0.024	1.638PheIle: 1.638 ± 0.034	0.874PheLys: 0.874 ± 0.028	3.353PheLeu: 3.353 ± 0.05	0.84PheMet: 0.84 ± 0.026	1.046PheAsn: 1.046 ± 0.03	1.567PhePro: 1.567 ± 0.033	1.069PheGln: 1.069 ± 0.027	2.097PheArg: 2.097 ± 0.04	2.144PheSer: 2.144 ± 0.034	1.985PheThr: 1.985 ± 0.039	2.834PheVal: 2.834 ± 0.042	0.611PheTrp: 0.611 ± 0.02	0.945PheTyr: 0.945 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	9.66GlyAla: 9.66 ± 0.097	0.895GlyCys: 0.895 ± 0.021	4.806GlyAsp: 4.806 ± 0.095	4.498GlyGlu: 4.498 ± 0.057	3.664GlyPhe: 3.664 ± 0.055	7.406GlyGly: 7.406 ± 0.114	1.922GlyHis: 1.922 ± 0.039	4.633GlyIle: 4.633 ± 0.059	2.895GlyLys: 2.895 ± 0.054	9.247GlyLeu: 9.247 ± 0.087	2.598GlyMet: 2.598 ± 0.049	2.192GlyAsn: 2.192 ± 0.065	4.03GlyPro: 4.03 ± 0.061	3.363GlyGln: 3.363 ± 0.053	5.659GlyArg: 5.659 ± 0.065	4.401GlySer: 4.401 ± 0.072	4.835GlyThr: 4.835 ± 0.073	6.401GlyVal: 6.401 ± 0.074	1.482GlyTrp: 1.482 ± 0.033	2.35GlyTyr: 2.35 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	2.25HisAla: 2.25 ± 0.043	0.227HisCys: 0.227 ± 0.012	1.343HisAsp: 1.343 ± 0.031	1.005HisGlu: 1.005 ± 0.025	0.851HisPhe: 0.851 ± 0.024	1.88HisGly: 1.88 ± 0.036	0.553HisHis: 0.553 ± 0.023	1.003HisIle: 1.003 ± 0.024	0.542HisLys: 0.542 ± 0.021	2.153HisLeu: 2.153 ± 0.042	0.547HisMet: 0.547 ± 0.023	0.478HisAsn: 0.478 ± 0.019	1.355HisPro: 1.355 ± 0.038	0.562HisGln: 0.562 ± 0.019	1.314HisArg: 1.314 ± 0.034	1.009HisSer: 1.009 ± 0.03	0.871HisThr: 0.871 ± 0.027	1.501HisVal: 1.501 ± 0.034	0.379HisTrp: 0.379 ± 0.015	0.545HisTyr: 0.545 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	7.025IleAla: 7.025 ± 0.081	0.63IleCys: 0.63 ± 0.021	3.834IleAsp: 3.834 ± 0.055	3.641IleGlu: 3.641 ± 0.049	1.737IlePhe: 1.737 ± 0.039	5.084IleGly: 5.084 ± 0.06	0.947IleHis: 0.947 ± 0.028	2.297IleIle: 2.297 ± 0.043	1.448IleLys: 1.448 ± 0.032	4.949IleLeu: 4.949 ± 0.073	1.212IleMet: 1.212 ± 0.03	1.424IleAsn: 1.424 ± 0.03	2.465IlePro: 2.465 ± 0.045	1.231IleGln: 1.231 ± 0.03	3.153IleArg: 3.153 ± 0.046	3.057IleSer: 3.057 ± 0.054	2.992IleThr: 2.992 ± 0.049	4.153IleVal: 4.153 ± 0.054	0.756IleTrp: 0.756 ± 0.027	1.192IleTyr: 1.192 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	3.722LysAla: 3.722 ± 0.063	0.162LysCys: 0.162 ± 0.01	1.654LysAsp: 1.654 ± 0.037	1.367LysGlu: 1.367 ± 0.035	0.835LysPhe: 0.835 ± 0.028	2.556LysGly: 2.556 ± 0.04	0.602LysHis: 0.602 ± 0.022	1.546LysIle: 1.546 ± 0.038	0.954LysLys: 0.954 ± 0.033	2.807LysLeu: 2.807 ± 0.055	0.812LysMet: 0.812 ± 0.027	0.664LysAsn: 0.664 ± 0.025	1.723LysPro: 1.723 ± 0.046	0.822LysGln: 0.822 ± 0.024	2.025LysArg: 2.025 ± 0.043	1.826LysSer: 1.826 ± 0.041	1.815LysThr: 1.815 ± 0.033	2.18LysVal: 2.18 ± 0.047	0.402LysTrp: 0.402 ± 0.018	0.558LysTyr: 0.558 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	12.691LeuAla: 12.691 ± 0.117	0.969LeuCys: 0.969 ± 0.029	5.984LeuAsp: 5.984 ± 0.059	5.122LeuGlu: 5.122 ± 0.068	3.482LeuPhe: 3.482 ± 0.059	8.424LeuGly: 8.424 ± 0.086	1.889LeuHis: 1.889 ± 0.038	5.551LeuIle: 5.551 ± 0.07	2.834LeuLys: 2.834 ± 0.05	8.638LeuLeu: 8.638 ± 0.099	2.71LeuMet: 2.71 ± 0.046	2.682LeuAsn: 2.682 ± 0.042	5.594LeuPro: 5.594 ± 0.072	2.719LeuGln: 2.719 ± 0.049	6.946LeuArg: 6.946 ± 0.073	6.748LeuSer: 6.748 ± 0.072	6.446LeuThr: 6.446 ± 0.07	6.546LeuVal: 6.546 ± 0.083	1.334LeuTrp: 1.334 ± 0.033	1.99LeuTyr: 1.99 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	3.607MetAla: 3.607 ± 0.056	0.206MetCys: 0.206 ± 0.012	1.42MetAsp: 1.42 ± 0.031	1.289MetGlu: 1.289 ± 0.03	0.855MetPhe: 0.855 ± 0.029	2.282MetGly: 2.282 ± 0.046	0.507MetHis: 0.507 ± 0.02	1.673MetIle: 1.673 ± 0.037	0.9MetLys: 0.9 ± 0.023	2.598MetLeu: 2.598 ± 0.043	0.809MetMet: 0.809 ± 0.022	0.811MetAsn: 0.811 ± 0.024	1.562MetPro: 1.562 ± 0.039	0.995MetGln: 0.995 ± 0.028	1.873MetArg: 1.873 ± 0.037	1.912MetSer: 1.912 ± 0.035	2.322MetThr: 2.322 ± 0.046	1.935MetVal: 1.935 ± 0.039	0.254MetTrp: 0.254 ± 0.013	0.37MetTyr: 0.37 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.16AsnAla: 3.16 ± 0.046	0.253AsnCys: 0.253 ± 0.012	1.567AsnAsp: 1.567 ± 0.061	1.173AsnGlu: 1.173 ± 0.03	0.968AsnPhe: 0.968 ± 0.027	2.488AsnGly: 2.488 ± 0.046	0.513AsnHis: 0.513 ± 0.017	1.356AsnIle: 1.356 ± 0.033	0.603AsnLys: 0.603 ± 0.023	2.488AsnLeu: 2.488 ± 0.045	0.697AsnMet: 0.697 ± 0.021	0.66AsnAsn: 0.66 ± 0.022	1.84AsnPro: 1.84 ± 0.034	0.72AsnGln: 0.72 ± 0.023	1.72AsnArg: 1.72 ± 0.037	1.226AsnSer: 1.226 ± 0.029	1.343AsnThr: 1.343 ± 0.029	1.898AsnVal: 1.898 ± 0.032	0.463AsnTrp: 0.463 ± 0.02	0.679AsnTyr: 0.679 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	5.771ProAla: 5.771 ± 0.084	0.355ProCys: 0.355 ± 0.014	4.261ProAsp: 4.261 ± 0.06	4.081ProGlu: 4.081 ± 0.058	1.945ProPhe: 1.945 ± 0.039	4.477ProGly: 4.477 ± 0.063	1.076ProHis: 1.076 ± 0.026	2.333ProIle: 2.333 ± 0.043	1.67ProLys: 1.67 ± 0.042	4.809ProLeu: 4.809 ± 0.061	1.415ProMet: 1.415 ± 0.033	1.455ProAsn: 1.455 ± 0.036	2.476ProPro: 2.476 ± 0.057	1.662ProGln: 1.662 ± 0.032	2.746ProArg: 2.746 ± 0.047	2.779ProSer: 2.779 ± 0.051	2.707ProThr: 2.707 ± 0.049	4.309ProVal: 4.309 ± 0.06	0.692ProTrp: 0.692 ± 0.02	1.197ProTyr: 1.197 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.899GlnAla: 3.899 ± 0.058	0.204GlnCys: 0.204 ± 0.012	1.672GlnAsp: 1.672 ± 0.032	1.588GlnGlu: 1.588 ± 0.035	1.121GlnPhe: 1.121 ± 0.029	2.554GlnGly: 2.554 ± 0.046	0.578GlnHis: 0.578 ± 0.02	2.177GlnIle: 2.177 ± 0.039	0.899GlnLys: 0.899 ± 0.025	2.821GlnLeu: 2.821 ± 0.054	1.115GlnMet: 1.115 ± 0.027	0.918GlnAsn: 0.918 ± 0.024	1.644GlnPro: 1.644 ± 0.035	0.99GlnGln: 0.99 ± 0.035	2.122GlnArg: 2.122 ± 0.045	2.043GlnSer: 2.043 ± 0.04	2.053GlnThr: 2.053 ± 0.041	2.381GlnVal: 2.381 ± 0.047	0.433GlnTrp: 0.433 ± 0.017	0.574GlnTyr: 0.574 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	7.574ArgAla: 7.574 ± 0.082	0.512ArgCys: 0.512 ± 0.019	4.214ArgAsp: 4.214 ± 0.07	3.523ArgGlu: 3.523 ± 0.049	2.616ArgPhe: 2.616 ± 0.045	4.45ArgGly: 4.45 ± 0.053	1.509ArgHis: 1.509 ± 0.032	3.935ArgIle: 3.935 ± 0.057	2.095ArgLys: 2.095 ± 0.044	6.95ArgLeu: 6.95 ± 0.092	1.988ArgMet: 1.988 ± 0.036	1.736ArgAsn: 1.736 ± 0.032	3.389ArgPro: 3.389 ± 0.057	2.251ArgGln: 2.251 ± 0.046	4.648ArgArg: 4.648 ± 0.065	3.406ArgSer: 3.406 ± 0.055	3.172ArgThr: 3.172 ± 0.049	4.455ArgVal: 4.455 ± 0.063	0.938ArgTrp: 0.938 ± 0.029	1.53ArgTyr: 1.53 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	6.047SerAla: 6.047 ± 0.078	0.448SerCys: 0.448 ± 0.019	3.54SerAsp: 3.54 ± 0.058	3.04SerGlu: 3.04 ± 0.048	2.349SerPhe: 2.349 ± 0.04	5.379SerGly: 5.379 ± 0.064	1.127SerHis: 1.127 ± 0.029	2.769SerIle: 2.769 ± 0.052	1.518SerLys: 1.518 ± 0.035	5.272SerLeu: 5.272 ± 0.066	1.367SerMet: 1.367 ± 0.032	1.422SerAsn: 1.422 ± 0.032	2.677SerPro: 2.677 ± 0.04	1.68SerGln: 1.68 ± 0.031	3.36SerArg: 3.36 ± 0.05	2.664SerSer: 2.664 ± 0.052	2.715SerThr: 2.715 ± 0.047	3.977SerVal: 3.977 ± 0.059	0.714SerTrp: 0.714 ± 0.02	1.373SerTyr: 1.373 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	6.395ThrAla: 6.395 ± 0.079	0.521ThrCys: 0.521 ± 0.018	3.501ThrAsp: 3.501 ± 0.056	3.1ThrGlu: 3.1 ± 0.055	2.083ThrPhe: 2.083 ± 0.037	5.612ThrGly: 5.612 ± 0.07	1.113ThrHis: 1.113 ± 0.029	2.964ThrIle: 2.964 ± 0.055	1.507ThrLys: 1.507 ± 0.035	6.192ThrLeu: 6.192 ± 0.067	1.336ThrMet: 1.336 ± 0.03	1.384ThrAsn: 1.384 ± 0.035	3.409ThrPro: 3.409 ± 0.05	1.666ThrGln: 1.666 ± 0.034	3.278ThrArg: 3.278 ± 0.05	2.946ThrSer: 2.946 ± 0.042	2.904ThrThr: 2.904 ± 0.048	4.433ThrVal: 4.433 ± 0.065	0.72ThrTrp: 0.72 ± 0.023	1.362ThrTyr: 1.362 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	8.783ValAla: 8.783 ± 0.087	0.674ValCys: 0.674 ± 0.021	4.274ValAsp: 4.274 ± 0.054	4.308ValGlu: 4.308 ± 0.061	2.835ValPhe: 2.835 ± 0.043	5.612ValGly: 5.612 ± 0.07	1.33ValHis: 1.33 ± 0.033	4.263ValIle: 4.263 ± 0.064	1.839ValLys: 1.839 ± 0.041	7.46ValLeu: 7.46 ± 0.085	2.102ValMet: 2.102 ± 0.04	1.978ValAsn: 1.978 ± 0.038	3.764ValPro: 3.764 ± 0.047	2.17ValGln: 2.17 ± 0.044	4.288ValArg: 4.288 ± 0.056	4.374ValSer: 4.374 ± 0.064	4.797ValThr: 4.797 ± 0.056	5.762ValVal: 5.762 ± 0.086	1.067ValTrp: 1.067 ± 0.026	1.528ValTyr: 1.528 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.439TrpAla: 1.439 ± 0.037	0.124TrpCys: 0.124 ± 0.008	0.862TrpAsp: 0.862 ± 0.025	0.72TrpGlu: 0.72 ± 0.023	0.571TrpPhe: 0.571 ± 0.021	1.025TrpGly: 1.025 ± 0.029	0.351TrpHis: 0.351 ± 0.015	0.777TrpIle: 0.777 ± 0.022	0.412TrpLys: 0.412 ± 0.017	1.605TrpLeu: 1.605 ± 0.037	0.424TrpMet: 0.424 ± 0.015	0.413TrpAsn: 0.413 ± 0.018	0.715TrpPro: 0.715 ± 0.022	0.653TrpGln: 0.653 ± 0.02	1.09TrpArg: 1.09 ± 0.027	0.862TrpSer: 0.862 ± 0.025	0.878TrpThr: 0.878 ± 0.027	0.913TrpVal: 0.913 ± 0.025	0.243TrpTrp: 0.243 ± 0.015	0.294TrpTyr: 0.294 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.624TyrAla: 2.624 ± 0.04	0.234TyrCys: 0.234 ± 0.015	1.644TyrAsp: 1.644 ± 0.034	1.239TyrGlu: 1.239 ± 0.033	0.964TyrPhe: 0.964 ± 0.028	2.12TyrGly: 2.12 ± 0.041	0.522TyrHis: 0.522 ± 0.021	0.936TyrIle: 0.936 ± 0.023	0.546TyrLys: 0.546 ± 0.021	2.235TyrLeu: 2.235 ± 0.039	0.493TyrMet: 0.493 ± 0.019	0.595TyrAsn: 0.595 ± 0.021	1.15TyrPro: 1.15 ± 0.034	0.681TyrGln: 0.681 ± 0.02	1.552TyrArg: 1.552 ± 0.028	1.203TyrSer: 1.203 ± 0.029	1.108TyrThr: 1.108 ± 0.029	1.668TyrVal: 1.668 ± 0.035	0.342TyrTrp: 0.342 ± 0.018	0.612TyrTyr: 0.612 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4548 proteins (1434317 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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