Amino acid dipepetide frequency for Chickpea chlorotic dwarf virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.906AlaAla: 3.906 ± 1.652
1.302AlaCys: 1.302 ± 1.044
2.604AlaAsp: 2.604 ± 1.821
2.604AlaGlu: 2.604 ± 0.83
0.0AlaPhe: 0.0 ± 0.0
1.302AlaGly: 1.302 ± 1.044
0.0AlaHis: 0.0 ± 0.0
0.0AlaIle: 0.0 ± 0.0
3.906AlaLys: 3.906 ± 2.372
5.208AlaLeu: 5.208 ± 1.542
0.0AlaMet: 0.0 ± 0.0
5.208AlaAsn: 5.208 ± 1.659
2.604AlaPro: 2.604 ± 2.088
1.302AlaGln: 1.302 ± 1.044
6.51AlaArg: 6.51 ± 2.668
2.604AlaSer: 2.604 ± 1.695
6.51AlaThr: 6.51 ± 1.813
0.0AlaVal: 0.0 ± 0.0
1.302AlaTrp: 1.302 ± 0.91
3.906AlaTyr: 3.906 ± 1.34
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.604CysGly: 2.604 ± 1.377
2.604CysHis: 2.604 ± 0.83
2.604CysIle: 2.604 ± 1.877
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
3.906CysAsn: 3.906 ± 2.114
1.302CysPro: 1.302 ± 1.044
1.302CysGln: 1.302 ± 1.389
1.302CysArg: 1.302 ± 1.044
1.302CysSer: 1.302 ± 0.91
1.302CysThr: 1.302 ± 1.044
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.906AspAla: 3.906 ± 2.731
1.302AspCys: 1.302 ± 1.516
5.208AspAsp: 5.208 ± 3.95
1.302AspGlu: 1.302 ± 1.389
6.51AspPhe: 6.51 ± 2.668
3.906AspGly: 3.906 ± 1.876
3.906AspHis: 3.906 ± 1.677
5.208AspIle: 5.208 ± 1.405
3.906AspLys: 3.906 ± 1.394
5.208AspLeu: 5.208 ± 3.641
1.302AspMet: 1.302 ± 0.91
5.208AspAsn: 5.208 ± 2.712
2.604AspPro: 2.604 ± 0.83
1.302AspGln: 1.302 ± 0.91
1.302AspArg: 1.302 ± 1.516
1.302AspSer: 1.302 ± 1.044
3.906AspThr: 3.906 ± 2.065
2.604AspVal: 2.604 ± 2.088
2.604AspTrp: 2.604 ± 1.377
1.302AspTyr: 1.302 ± 0.91
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
0.0GluCys: 0.0 ± 0.0
3.906GluAsp: 3.906 ± 2.611
2.604GluGlu: 2.604 ± 1.821
2.604GluPhe: 2.604 ± 1.821
5.208GluGly: 5.208 ± 1.659
0.0GluHis: 0.0 ± 0.0
1.302GluIle: 1.302 ± 1.516
1.302GluLys: 1.302 ± 0.91
1.302GluLeu: 1.302 ± 0.91
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
1.302GluPro: 1.302 ± 0.91
1.302GluGln: 1.302 ± 0.91
1.302GluArg: 1.302 ± 0.91
7.812GluSer: 7.812 ± 1.793
0.0GluThr: 0.0 ± 0.0
1.302GluVal: 1.302 ± 0.91
2.604GluTrp: 2.604 ± 0.83
3.906GluTyr: 3.906 ± 1.876
0.0GluXaa: 0.0 ± 0.0
Phe
1.302PheAla: 1.302 ± 1.389
0.0PheCys: 0.0 ± 0.0
1.302PheAsp: 1.302 ± 0.91
3.906PheGlu: 3.906 ± 0.919
3.906PhePhe: 3.906 ± 0.919
2.604PheGly: 2.604 ± 3.032
0.0PheHis: 0.0 ± 0.0
1.302PheIle: 1.302 ± 0.91
5.208PheLys: 5.208 ± 2.242
5.208PheLeu: 5.208 ± 2.781
1.302PheMet: 1.302 ± 1.044
0.0PheAsn: 0.0 ± 0.0
6.51PhePro: 6.51 ± 1.634
1.302PheGln: 1.302 ± 0.91
5.208PheArg: 5.208 ± 1.659
3.906PheSer: 3.906 ± 2.372
5.208PheThr: 5.208 ± 2.204
2.604PheVal: 2.604 ± 1.452
1.302PheTrp: 1.302 ± 1.044
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
7.812GlyAla: 7.812 ± 6.265
1.302GlyCys: 1.302 ± 1.389
6.51GlyAsp: 6.51 ± 1.066
0.0GlyGlu: 0.0 ± 0.0
1.302GlyPhe: 1.302 ± 1.516
2.604GlyGly: 2.604 ± 1.452
0.0GlyHis: 0.0 ± 0.0
5.208GlyIle: 5.208 ± 2.904
5.208GlyLys: 5.208 ± 2.904
2.604GlyLeu: 2.604 ± 1.821
1.302GlyMet: 1.302 ± 0.91
2.604GlyAsn: 2.604 ± 0.83
5.208GlyPro: 5.208 ± 3.002
1.302GlyGln: 1.302 ± 1.516
3.906GlyArg: 3.906 ± 2.933
6.51GlySer: 6.51 ± 2.396
2.604GlyThr: 2.604 ± 1.377
3.906GlyVal: 3.906 ± 1.34
0.0GlyTrp: 0.0 ± 0.0
1.302GlyTyr: 1.302 ± 1.044
0.0GlyXaa: 0.0 ± 0.0
His
2.604HisAla: 2.604 ± 1.377
1.302HisCys: 1.302 ± 0.91
0.0HisAsp: 0.0 ± 0.0
2.604HisGlu: 2.604 ± 1.821
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.302HisIle: 1.302 ± 0.91
1.302HisLys: 1.302 ± 0.91
1.302HisLeu: 1.302 ± 1.06
1.302HisMet: 1.302 ± 0.921
1.302HisAsn: 1.302 ± 1.389
3.906HisPro: 3.906 ± 1.677
1.302HisGln: 1.302 ± 0.91
1.302HisArg: 1.302 ± 1.044
0.0HisSer: 0.0 ± 0.0
2.604HisThr: 2.604 ± 0.83
1.302HisVal: 1.302 ± 0.91
0.0HisTrp: 0.0 ± 0.0
3.906HisTyr: 3.906 ± 0.919
0.0HisXaa: 0.0 ± 0.0
Ile
1.302IleAla: 1.302 ± 1.516
1.302IleCys: 1.302 ± 1.389
5.208IleAsp: 5.208 ± 2.204
0.0IleGlu: 0.0 ± 0.0
1.302IlePhe: 1.302 ± 1.044
3.906IleGly: 3.906 ± 1.677
1.302IleHis: 1.302 ± 0.91
3.906IleIle: 3.906 ± 2.611
6.51IleLys: 6.51 ± 1.066
3.906IleLeu: 3.906 ± 3.116
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
2.604IlePro: 2.604 ± 2.778
3.906IleGln: 3.906 ± 2.731
2.604IleArg: 2.604 ± 1.377
3.906IleSer: 3.906 ± 2.731
1.302IleThr: 1.302 ± 1.389
1.302IleVal: 1.302 ± 1.044
0.0IleTrp: 0.0 ± 0.0
2.604IleTyr: 2.604 ± 0.83
0.0IleXaa: 0.0 ± 0.0
Lys
3.906LysAla: 3.906 ± 2.372
1.302LysCys: 1.302 ± 0.91
2.604LysAsp: 2.604 ± 1.566
5.208LysGlu: 5.208 ± 1.112
5.208LysPhe: 5.208 ± 3.002
1.302LysGly: 1.302 ± 1.389
1.302LysHis: 1.302 ± 0.91
2.604LysIle: 2.604 ± 1.377
7.812LysLys: 7.812 ± 3.925
3.906LysLeu: 3.906 ± 2.731
0.0LysMet: 0.0 ± 0.0
3.906LysAsn: 3.906 ± 1.652
0.0LysPro: 0.0 ± 0.0
3.906LysGln: 3.906 ± 1.677
5.208LysArg: 5.208 ± 2.636
6.51LysSer: 6.51 ± 3.654
5.208LysThr: 5.208 ± 1.405
1.302LysVal: 1.302 ± 1.044
0.0LysTrp: 0.0 ± 0.0
2.604LysTyr: 2.604 ± 1.377
0.0LysXaa: 0.0 ± 0.0
Leu
2.604LeuAla: 2.604 ± 1.566
1.302LeuCys: 1.302 ± 1.389
6.51LeuAsp: 6.51 ± 3.07
3.906LeuGlu: 3.906 ± 2.731
5.208LeuPhe: 5.208 ± 2.739
3.906LeuGly: 3.906 ± 0.919
1.302LeuHis: 1.302 ± 0.91
3.906LeuIle: 3.906 ± 1.876
1.302LeuLys: 1.302 ± 1.516
2.604LeuLeu: 2.604 ± 1.566
0.0LeuMet: 0.0 ± 0.0
1.302LeuAsn: 1.302 ± 1.389
0.0LeuPro: 0.0 ± 0.0
2.604LeuGln: 2.604 ± 0.83
1.302LeuArg: 1.302 ± 0.91
0.0LeuSer: 0.0 ± 0.0
3.906LeuThr: 3.906 ± 2.731
6.51LeuVal: 6.51 ± 2.917
2.604LeuTrp: 2.604 ± 1.377
6.51LeuTyr: 6.51 ± 1.364
0.0LeuXaa: 0.0 ± 0.0
Met
2.604MetAla: 2.604 ± 0.83
0.0MetCys: 0.0 ± 0.0
1.302MetAsp: 1.302 ± 1.516
1.302MetGlu: 1.302 ± 0.91
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.302MetIle: 1.302 ± 0.91
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.604MetPro: 2.604 ± 1.821
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
2.604MetSer: 2.604 ± 1.452
1.302MetThr: 1.302 ± 0.91
1.302MetVal: 1.302 ± 0.91
0.0MetTrp: 0.0 ± 0.0
1.302MetTyr: 1.302 ± 1.389
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
2.604AsnCys: 2.604 ± 1.452
1.302AsnAsp: 1.302 ± 1.044
0.0AsnGlu: 0.0 ± 0.0
5.208AsnPhe: 5.208 ± 1.116
3.906AsnGly: 3.906 ± 2.114
1.302AsnHis: 1.302 ± 0.91
2.604AsnIle: 2.604 ± 1.377
5.208AsnLys: 5.208 ± 1.659
0.0AsnLeu: 0.0 ± 0.0
0.0AsnMet: 0.0 ± 0.0
1.302AsnAsn: 1.302 ± 1.044
5.208AsnPro: 5.208 ± 2.712
5.208AsnGln: 5.208 ± 2.242
0.0AsnArg: 0.0 ± 0.0
2.604AsnSer: 2.604 ± 0.83
1.302AsnThr: 1.302 ± 1.044
1.302AsnVal: 1.302 ± 1.044
0.0AsnTrp: 0.0 ± 0.0
1.302AsnTyr: 1.302 ± 1.389
0.0AsnXaa: 0.0 ± 0.0
Pro
3.906ProAla: 3.906 ± 2.945
1.302ProCys: 1.302 ± 1.044
1.302ProAsp: 1.302 ± 1.389
2.604ProGlu: 2.604 ± 1.821
5.208ProPhe: 5.208 ± 1.112
5.208ProGly: 5.208 ± 2.636
2.604ProHis: 2.604 ± 1.821
0.0ProIle: 0.0 ± 0.0
2.604ProLys: 2.604 ± 1.377
1.302ProLeu: 1.302 ± 1.771
1.302ProMet: 1.302 ± 1.162
2.604ProAsn: 2.604 ± 0.83
6.51ProPro: 6.51 ± 3.551
3.906ProGln: 3.906 ± 1.34
1.302ProArg: 1.302 ± 1.044
15.625ProSer: 15.625 ± 1.888
2.604ProThr: 2.604 ± 1.377
2.604ProVal: 2.604 ± 1.566
1.302ProTrp: 1.302 ± 1.044
1.302ProTyr: 1.302 ± 0.91
0.0ProXaa: 0.0 ± 0.0
Gln
1.302GlnAla: 1.302 ± 0.91
0.0GlnCys: 0.0 ± 0.0
3.906GlnAsp: 3.906 ± 1.677
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
2.604GlnGly: 2.604 ± 2.088
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
2.604GlnLys: 2.604 ± 1.452
5.208GlnLeu: 5.208 ± 1.845
0.0GlnMet: 0.0 ± 0.816
0.0GlnAsn: 0.0 ± 0.0
3.906GlnPro: 3.906 ± 2.065
1.302GlnGln: 1.302 ± 1.389
3.906GlnArg: 3.906 ± 2.065
2.604GlnSer: 2.604 ± 1.377
3.906GlnThr: 3.906 ± 2.945
5.208GlnVal: 5.208 ± 1.822
1.302GlnTrp: 1.302 ± 0.91
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.906ArgAla: 3.906 ± 3.132
2.604ArgCys: 2.604 ± 0.83
5.208ArgAsp: 5.208 ± 3.641
2.604ArgGlu: 2.604 ± 1.452
2.604ArgPhe: 2.604 ± 0.83
1.302ArgGly: 1.302 ± 0.91
3.906ArgHis: 3.906 ± 2.643
1.302ArgIle: 1.302 ± 1.516
1.302ArgLys: 1.302 ± 1.044
1.302ArgLeu: 1.302 ± 1.044
0.0ArgMet: 0.0 ± 0.0
2.604ArgAsn: 2.604 ± 1.566
2.604ArgPro: 2.604 ± 1.821
0.0ArgGln: 0.0 ± 0.0
1.302ArgArg: 1.302 ± 1.044
5.208ArgSer: 5.208 ± 2.904
6.51ArgThr: 6.51 ± 2.524
2.604ArgVal: 2.604 ± 1.695
1.302ArgTrp: 1.302 ± 0.91
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.208SerAla: 5.208 ± 2.204
2.604SerCys: 2.604 ± 2.088
11.719SerAsp: 11.719 ± 2.4
0.0SerGlu: 0.0 ± 0.0
1.302SerPhe: 1.302 ± 0.91
7.812SerGly: 7.812 ± 4.228
3.906SerHis: 3.906 ± 0.919
3.906SerIle: 3.906 ± 1.876
6.51SerLys: 6.51 ± 3.07
5.208SerLeu: 5.208 ± 2.933
1.302SerMet: 1.302 ± 1.234
2.604SerAsn: 2.604 ± 2.088
5.208SerPro: 5.208 ± 2.781
6.51SerGln: 6.51 ± 0.983
5.208SerArg: 5.208 ± 4.176
16.927SerSer: 16.927 ± 2.393
10.417SerThr: 10.417 ± 5.272
3.906SerVal: 3.906 ± 2.372
1.302SerTrp: 1.302 ± 1.044
3.906SerTyr: 3.906 ± 1.34
0.0SerXaa: 0.0 ± 0.0
Thr
1.302ThrAla: 1.302 ± 0.91
0.0ThrCys: 0.0 ± 0.0
1.302ThrAsp: 1.302 ± 1.516
5.208ThrGlu: 5.208 ± 1.542
2.604ThrPhe: 2.604 ± 2.088
3.906ThrGly: 3.906 ± 0.919
2.604ThrHis: 2.604 ± 1.377
3.906ThrIle: 3.906 ± 0.919
2.604ThrLys: 2.604 ± 1.821
1.302ThrLeu: 1.302 ± 1.516
3.906ThrMet: 3.906 ± 2.731
2.604ThrAsn: 2.604 ± 1.695
3.906ThrPro: 3.906 ± 2.065
0.0ThrGln: 0.0 ± 0.0
3.906ThrArg: 3.906 ± 1.876
9.115ThrSer: 9.115 ± 3.183
13.021ThrThr: 13.021 ± 5.048
7.812ThrVal: 7.812 ± 2.157
5.208ThrTrp: 5.208 ± 3.002
6.51ThrTyr: 6.51 ± 2.095
0.0ThrXaa: 0.0 ± 0.0
Val
2.604ValAla: 2.604 ± 0.83
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
1.302ValGlu: 1.302 ± 1.044
3.906ValPhe: 3.906 ± 1.34
5.208ValGly: 5.208 ± 3.25
0.0ValHis: 0.0 ± 0.0
1.302ValIle: 1.302 ± 1.516
2.604ValLys: 2.604 ± 2.088
3.906ValLeu: 3.906 ± 1.34
0.0ValMet: 0.0 ± 0.0
2.604ValAsn: 2.604 ± 1.452
7.812ValPro: 7.812 ± 1.838
0.0ValGln: 0.0 ± 0.0
0.0ValArg: 0.0 ± 0.0
13.021ValSer: 13.021 ± 3.38
2.604ValThr: 2.604 ± 1.695
6.51ValVal: 6.51 ± 5.983
0.0ValTrp: 0.0 ± 0.0
5.208ValTyr: 5.208 ± 3.25
0.0ValXaa: 0.0 ± 0.0
Trp
2.604TrpAla: 2.604 ± 1.377
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.302TrpGlu: 1.302 ± 0.91
0.0TrpPhe: 0.0 ± 0.0
1.302TrpGly: 1.302 ± 1.044
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.604TrpLys: 2.604 ± 1.452
2.604TrpLeu: 2.604 ± 0.83
1.302TrpMet: 1.302 ± 0.91
1.302TrpAsn: 1.302 ± 1.389
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.604TrpArg: 2.604 ± 1.821
1.302TrpSer: 1.302 ± 1.044
3.906TrpThr: 3.906 ± 3.132
1.302TrpVal: 1.302 ± 1.389
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
3.906TyrAsp: 3.906 ± 1.785
1.302TyrGlu: 1.302 ± 0.91
5.208TyrPhe: 5.208 ± 1.405
2.604TyrGly: 2.604 ± 1.452
2.604TyrHis: 2.604 ± 1.821
5.208TyrIle: 5.208 ± 1.112
1.302TyrLys: 1.302 ± 1.044
5.208TyrLeu: 5.208 ± 1.822
1.302TyrMet: 1.302 ± 1.389
1.302TyrAsn: 1.302 ± 1.389
1.302TyrPro: 1.302 ± 0.91
1.302TyrGln: 1.302 ± 1.516
0.0TyrArg: 0.0 ± 0.0
3.906TyrSer: 3.906 ± 0.919
2.604TyrThr: 2.604 ± 1.566
5.208TyrVal: 5.208 ± 1.659
1.302TyrTrp: 1.302 ± 1.389
1.302TyrTyr: 1.302 ± 1.044
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (769 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski