Rupicapra rupicapra papillomavirus 1

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Dyokappapapillomavirus; Dyokappapapillomavirus 2

Average proteome isoelectric point is 6.02

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|X2DFB2|X2DFB2_9PAPI Replication protein E1 OS=Rupicapra rupicapra papillomavirus 1 OX=1163708 GN=E1 PE=3 SV=1
MM1 pKa = 8.07RR2 pKa = 11.84GQQPTLPDD10 pKa = 3.56VVLHH14 pKa = 6.37EE15 pKa = 4.46LPEE18 pKa = 4.3PVSLFCEE25 pKa = 4.13EE26 pKa = 3.9QLEE29 pKa = 4.33EE30 pKa = 4.42EE31 pKa = 4.65EE32 pKa = 4.37EE33 pKa = 3.99QGAQYY38 pKa = 10.04TVYY41 pKa = 9.26TVCGRR46 pKa = 11.84CRR48 pKa = 11.84HH49 pKa = 5.42RR50 pKa = 11.84LKK52 pKa = 11.37LNICASAEE60 pKa = 3.84SRR62 pKa = 11.84RR63 pKa = 11.84AFEE66 pKa = 4.69SLLLGDD72 pKa = 4.76LQILCLPCGDD82 pKa = 3.92

Molecular weight: 9.28 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|X2DH11|X2DH11_9PAPI Major capsid protein L1 OS=Rupicapra rupicapra papillomavirus 1 OX=1163708 GN=L1 PE=3 SV=1
MM1 pKa = 7.57EE2 pKa = 6.46GYY4 pKa = 9.32PKK6 pKa = 10.41TIAQLAAHH14 pKa = 6.54SNFADD19 pKa = 3.41SHH21 pKa = 6.69LLLPCIFCGDD31 pKa = 4.18FLTAADD37 pKa = 4.51VIHH40 pKa = 7.19FDD42 pKa = 3.87TAPLTLLWRR51 pKa = 11.84FGFPYY56 pKa = 10.07ACCIRR61 pKa = 11.84CCNYY65 pKa = 10.94AGMLEE70 pKa = 4.28AYY72 pKa = 9.85RR73 pKa = 11.84YY74 pKa = 8.39FQGLIPAAWVEE85 pKa = 4.24QITGLSLLQLDD96 pKa = 4.56VRR98 pKa = 11.84CVTCLRR104 pKa = 11.84RR105 pKa = 11.84CSLGDD110 pKa = 3.41KK111 pKa = 10.87LSVLWRR117 pKa = 11.84SSDD120 pKa = 3.53FFVVRR125 pKa = 11.84NRR127 pKa = 11.84LKK129 pKa = 9.75TVCQICGDD137 pKa = 3.65AWSAAHH143 pKa = 6.87SSS145 pKa = 3.39

Molecular weight: 16.25 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

0

6

2240

82

605

373.3

41.91

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.804 ± 0.626

2.5 ± 0.671

6.161 ± 0.438

6.384 ± 0.816

4.107 ± 0.434

7.366 ± 1.267

2.411 ± 0.117

3.661 ± 0.39

4.688 ± 0.802

8.973 ± 0.831

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.607 ± 0.362

3.17 ± 0.519

6.205 ± 1.004

4.955 ± 0.829

6.607 ± 0.568

7.723 ± 0.657

5.58 ± 0.533

7.232 ± 0.985

1.875 ± 0.326

2.991 ± 0.282
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski