Amino acid dipepetide frequency for Rupicapra rupicapra papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.36AlaAla: 5.36 ± 2.686
2.68AlaCys: 2.68 ± 1.232
2.68AlaAsp: 2.68 ± 1.23
5.806AlaGlu: 5.806 ± 1.747
2.233AlaPhe: 2.233 ± 0.998
4.913AlaGly: 4.913 ± 2.007
1.34AlaHis: 1.34 ± 1.283
2.233AlaIle: 2.233 ± 1.004
3.126AlaLys: 3.126 ± 1.175
2.68AlaLeu: 2.68 ± 1.31
1.34AlaMet: 1.34 ± 0.617
1.787AlaAsn: 1.787 ± 0.712
4.02AlaPro: 4.02 ± 1.363
4.02AlaGln: 4.02 ± 1.413
1.787AlaArg: 1.787 ± 0.941
3.126AlaSer: 3.126 ± 1.289
4.466AlaThr: 4.466 ± 0.788
1.787AlaVal: 1.787 ± 0.571
1.787AlaTrp: 1.787 ± 1.275
0.893AlaTyr: 0.893 ± 0.637
0.0AlaXaa: 0.0 ± 0.0
Cys
1.787CysAla: 1.787 ± 1.141
0.893CysCys: 0.893 ± 1.177
1.34CysAsp: 1.34 ± 0.646
0.447CysGlu: 0.447 ± 1.084
0.893CysPhe: 0.893 ± 0.437
2.233CysGly: 2.233 ± 2.656
0.447CysHis: 0.447 ± 0.4
1.787CysIle: 1.787 ± 1.106
2.233CysLys: 2.233 ± 0.537
2.68CysLeu: 2.68 ± 1.552
0.447CysMet: 0.447 ± 0.4
0.893CysAsn: 0.893 ± 0.637
1.787CysPro: 1.787 ± 0.707
1.34CysGln: 1.34 ± 0.602
1.34CysArg: 1.34 ± 1.018
1.34CysSer: 1.34 ± 0.813
0.893CysThr: 0.893 ± 0.437
1.34CysVal: 1.34 ± 0.691
0.893CysTrp: 0.893 ± 0.437
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.02AspAla: 4.02 ± 1.21
1.34AspCys: 1.34 ± 0.646
2.233AspAsp: 2.233 ± 0.82
4.466AspGlu: 4.466 ± 1.794
4.02AspPhe: 4.02 ± 1.288
5.36AspGly: 5.36 ± 1.063
1.34AspHis: 1.34 ± 0.427
1.34AspIle: 1.34 ± 0.432
2.68AspLys: 2.68 ± 1.476
7.593AspLeu: 7.593 ± 1.628
0.893AspMet: 0.893 ± 0.935
1.787AspAsn: 1.787 ± 0.882
3.573AspPro: 3.573 ± 2.247
1.34AspGln: 1.34 ± 0.65
2.233AspArg: 2.233 ± 0.81
6.699AspSer: 6.699 ± 2.048
4.02AspThr: 4.02 ± 0.652
5.36AspVal: 5.36 ± 2.676
0.0AspTrp: 0.0 ± 0.0
1.34AspTyr: 1.34 ± 0.646
0.0AspXaa: 0.0 ± 0.0
Glu
5.806GluAla: 5.806 ± 1.86
1.34GluCys: 1.34 ± 0.777
4.913GluAsp: 4.913 ± 1.176
6.253GluGlu: 6.253 ± 5.047
1.34GluPhe: 1.34 ± 0.779
4.02GluGly: 4.02 ± 1.736
1.34GluHis: 1.34 ± 0.432
2.233GluIle: 2.233 ± 1.187
2.233GluLys: 2.233 ± 1.196
5.36GluLeu: 5.36 ± 1.093
2.68GluMet: 2.68 ± 1.31
4.02GluAsn: 4.02 ± 1.289
2.233GluPro: 2.233 ± 1.31
4.02GluGln: 4.02 ± 2.123
1.787GluArg: 1.787 ± 0.874
4.913GluSer: 4.913 ± 2.072
2.68GluThr: 2.68 ± 1.077
4.913GluVal: 4.913 ± 1.04
0.893GluTrp: 0.893 ± 0.625
0.893GluTyr: 0.893 ± 0.441
0.0GluXaa: 0.0 ± 0.0
Phe
2.68PheAla: 2.68 ± 0.907
1.34PheCys: 1.34 ± 1.254
2.68PheAsp: 2.68 ± 0.763
1.34PheGlu: 1.34 ± 1.292
1.34PhePhe: 1.34 ± 0.602
4.02PheGly: 4.02 ± 1.105
1.34PheHis: 1.34 ± 0.417
2.68PheIle: 2.68 ± 1.087
2.233PheLys: 2.233 ± 0.394
5.806PheLeu: 5.806 ± 1.304
0.893PheMet: 0.893 ± 0.625
1.34PheAsn: 1.34 ± 0.781
1.787PhePro: 1.787 ± 0.636
1.34PheGln: 1.34 ± 0.725
1.34PheArg: 1.34 ± 0.938
1.787PheSer: 1.787 ± 0.589
1.787PheThr: 1.787 ± 0.571
2.233PheVal: 2.233 ± 0.671
1.787PheTrp: 1.787 ± 0.882
1.34PheTyr: 1.34 ± 0.779
0.0PheXaa: 0.0 ± 0.0
Gly
3.126GlyAla: 3.126 ± 1.595
0.447GlyCys: 0.447 ± 0.403
6.253GlyAsp: 6.253 ± 2.736
5.806GlyGlu: 5.806 ± 1.049
1.787GlyPhe: 1.787 ± 0.743
4.466GlyGly: 4.466 ± 2.911
2.233GlyHis: 2.233 ± 1.208
2.68GlyIle: 2.68 ± 0.835
1.787GlyLys: 1.787 ± 0.712
7.593GlyLeu: 7.593 ± 1.582
1.34GlyMet: 1.34 ± 0.741
0.893GlyAsn: 0.893 ± 0.467
4.913GlyPro: 4.913 ± 2.85
2.68GlyGln: 2.68 ± 1.229
7.593GlyArg: 7.593 ± 2.263
4.466GlySer: 4.466 ± 0.707
8.039GlyThr: 8.039 ± 2.391
5.806GlyVal: 5.806 ± 1.515
0.447GlyTrp: 0.447 ± 0.4
1.34GlyTyr: 1.34 ± 0.881
0.0GlyXaa: 0.0 ± 0.0
His
0.893HisAla: 0.893 ± 0.806
0.447HisCys: 0.447 ± 0.388
0.0HisAsp: 0.0 ± 0.0
1.34HisGlu: 1.34 ± 1.018
1.787HisPhe: 1.787 ± 0.757
1.787HisGly: 1.787 ± 0.683
0.447HisHis: 0.447 ± 0.313
0.447HisIle: 0.447 ± 0.313
0.447HisLys: 0.447 ± 0.4
1.787HisLeu: 1.787 ± 0.636
0.893HisMet: 0.893 ± 0.454
0.447HisAsn: 0.447 ± 0.403
3.126HisPro: 3.126 ± 0.72
1.787HisGln: 1.787 ± 0.92
2.233HisArg: 2.233 ± 1.035
2.68HisSer: 2.68 ± 1.141
0.447HisThr: 0.447 ± 0.388
0.893HisVal: 0.893 ± 0.437
1.34HisTrp: 1.34 ± 0.432
0.893HisTyr: 0.893 ± 0.467
0.0HisXaa: 0.0 ± 0.0
Ile
2.68IleAla: 2.68 ± 1.14
1.787IleCys: 1.787 ± 1.327
3.573IleAsp: 3.573 ± 0.896
2.68IleGlu: 2.68 ± 0.853
0.893IlePhe: 0.893 ± 0.746
1.787IleGly: 1.787 ± 1.111
1.787IleHis: 1.787 ± 0.743
0.0IleIle: 0.0 ± 0.0
0.447IleLys: 0.447 ± 0.403
4.02IleLeu: 4.02 ± 1.026
0.0IleMet: 0.0 ± 0.0
0.447IleAsn: 0.447 ± 0.388
3.126IlePro: 3.126 ± 0.982
0.893IleGln: 0.893 ± 0.441
0.893IleArg: 0.893 ± 0.607
3.126IleSer: 3.126 ± 1.169
2.68IleThr: 2.68 ± 0.498
4.466IleVal: 4.466 ± 1.677
0.0IleTrp: 0.0 ± 0.0
1.34IleTyr: 1.34 ± 0.427
0.0IleXaa: 0.0 ± 0.0
Lys
2.68LysAla: 2.68 ± 1.076
2.68LysCys: 2.68 ± 1.124
3.573LysAsp: 3.573 ± 1.176
1.34LysGlu: 1.34 ± 0.777
2.233LysPhe: 2.233 ± 0.839
2.68LysGly: 2.68 ± 0.553
3.126LysHis: 3.126 ± 0.684
0.893LysIle: 0.893 ± 0.806
4.913LysLys: 4.913 ± 1.693
4.02LysLeu: 4.02 ± 1.29
0.0LysMet: 0.0 ± 0.377
0.0LysAsn: 0.0 ± 0.0
1.787LysPro: 1.787 ± 0.934
2.233LysGln: 2.233 ± 0.776
2.68LysArg: 2.68 ± 0.835
2.68LysSer: 2.68 ± 1.323
2.233LysThr: 2.233 ± 1.204
4.466LysVal: 4.466 ± 1.491
0.893LysTrp: 0.893 ± 0.441
1.34LysTyr: 1.34 ± 0.432
0.0LysXaa: 0.0 ± 0.0
Leu
2.68LeuAla: 2.68 ± 1.232
2.68LeuCys: 2.68 ± 1.107
5.36LeuAsp: 5.36 ± 1.066
2.233LeuGlu: 2.233 ± 1.107
3.573LeuPhe: 3.573 ± 1.232
6.699LeuGly: 6.699 ± 1.737
2.233LeuHis: 2.233 ± 0.918
3.126LeuIle: 3.126 ± 1.087
4.466LeuLys: 4.466 ± 1.564
9.379LeuLeu: 9.379 ± 2.554
1.34LeuMet: 1.34 ± 0.627
2.233LeuAsn: 2.233 ± 1.134
6.253LeuPro: 6.253 ± 3.849
7.146LeuGln: 7.146 ± 1.423
7.593LeuArg: 7.593 ± 1.439
7.593LeuSer: 7.593 ± 1.534
4.02LeuThr: 4.02 ± 0.869
5.806LeuVal: 5.806 ± 1.316
2.68LeuTrp: 2.68 ± 1.164
2.68LeuTyr: 2.68 ± 0.561
0.0LeuXaa: 0.0 ± 0.0
Met
2.233MetAla: 2.233 ± 0.81
0.0MetCys: 0.0 ± 0.0
1.34MetAsp: 1.34 ± 1.208
1.34MetGlu: 1.34 ± 0.741
0.447MetPhe: 0.447 ± 0.403
0.447MetGly: 0.447 ± 0.403
0.447MetHis: 0.447 ± 0.4
0.0MetIle: 0.0 ± 0.0
0.447MetLys: 0.447 ± 0.313
0.893MetLeu: 0.893 ± 0.746
0.447MetMet: 0.447 ± 0.403
0.447MetAsn: 0.447 ± 0.4
0.893MetPro: 0.893 ± 0.625
1.34MetGln: 1.34 ± 0.432
1.787MetArg: 1.787 ± 1.235
1.787MetSer: 1.787 ± 0.895
0.0MetThr: 0.0 ± 0.0
1.34MetVal: 1.34 ± 0.646
0.0MetTrp: 0.0 ± 0.0
0.447MetTyr: 0.447 ± 0.313
0.0MetXaa: 0.0 ± 0.0
Asn
1.34AsnAla: 1.34 ± 0.646
0.447AsnCys: 0.447 ± 0.313
0.0AsnAsp: 0.0 ± 0.0
3.126AsnGlu: 3.126 ± 1.393
1.34AsnPhe: 1.34 ± 0.602
1.34AsnGly: 1.34 ± 0.779
0.447AsnHis: 0.447 ± 0.313
2.233AsnIle: 2.233 ± 1.183
5.36AsnLys: 5.36 ± 2.122
3.126AsnLeu: 3.126 ± 1.948
0.893AsnMet: 0.893 ± 0.441
1.787AsnAsn: 1.787 ± 0.882
0.893AsnPro: 0.893 ± 0.467
0.447AsnGln: 0.447 ± 0.313
2.68AsnArg: 2.68 ± 0.972
1.787AsnSer: 1.787 ± 0.915
0.893AsnThr: 0.893 ± 0.471
0.893AsnVal: 0.893 ± 0.465
1.34AsnTrp: 1.34 ± 0.432
1.34AsnTyr: 1.34 ± 0.691
0.0AsnXaa: 0.0 ± 0.0
Pro
5.36ProAla: 5.36 ± 1.597
0.893ProCys: 0.893 ± 1.306
4.913ProAsp: 4.913 ± 2.032
4.913ProGlu: 4.913 ± 0.99
2.233ProPhe: 2.233 ± 0.537
1.34ProGly: 1.34 ± 0.757
0.447ProHis: 0.447 ± 0.403
1.787ProIle: 1.787 ± 0.667
5.36ProLys: 5.36 ± 1.495
5.36ProLeu: 5.36 ± 1.121
0.447ProMet: 0.447 ± 0.4
1.787ProAsn: 1.787 ± 1.148
7.146ProPro: 7.146 ± 2.357
0.893ProGln: 0.893 ± 0.415
1.34ProArg: 1.34 ± 0.776
3.573ProSer: 3.573 ± 0.804
4.913ProThr: 4.913 ± 2.196
4.913ProVal: 4.913 ± 2.149
1.787ProTrp: 1.787 ± 0.667
2.68ProTyr: 2.68 ± 0.989
0.0ProXaa: 0.0 ± 0.0
Gln
0.893GlnAla: 0.893 ± 0.471
1.787GlnCys: 1.787 ± 0.915
0.893GlnAsp: 0.893 ± 0.471
4.913GlnGlu: 4.913 ± 1.283
0.893GlnPhe: 0.893 ± 0.467
5.806GlnGly: 5.806 ± 1.187
0.0GlnHis: 0.0 ± 0.0
3.126GlnIle: 3.126 ± 1.555
1.787GlnLys: 1.787 ± 0.707
4.02GlnLeu: 4.02 ± 1.493
0.893GlnMet: 0.893 ± 0.806
1.34GlnAsn: 1.34 ± 0.776
1.787GlnPro: 1.787 ± 1.007
3.573GlnGln: 3.573 ± 1.377
4.466GlnArg: 4.466 ± 3.498
5.36GlnSer: 5.36 ± 0.981
1.34GlnThr: 1.34 ± 0.417
3.126GlnVal: 3.126 ± 0.574
0.447GlnTrp: 0.447 ± 0.313
3.126GlnTyr: 3.126 ± 1.338
0.0GlnXaa: 0.0 ± 0.0
Arg
3.573ArgAla: 3.573 ± 1.212
1.787ArgCys: 1.787 ± 2.201
3.126ArgAsp: 3.126 ± 0.639
3.573ArgGlu: 3.573 ± 0.969
2.68ArgPhe: 2.68 ± 0.549
5.806ArgGly: 5.806 ± 2.206
2.68ArgHis: 2.68 ± 0.954
2.233ArgIle: 2.233 ± 0.796
3.126ArgLys: 3.126 ± 0.639
4.913ArgLeu: 4.913 ± 1.016
0.893ArgMet: 0.893 ± 0.441
2.68ArgAsn: 2.68 ± 0.927
4.466ArgPro: 4.466 ± 1.485
5.36ArgGln: 5.36 ± 3.829
9.379ArgArg: 9.379 ± 0.459
3.573ArgSer: 3.573 ± 1.236
0.447ArgThr: 0.447 ± 0.313
3.126ArgVal: 3.126 ± 1.067
0.0ArgTrp: 0.0 ± 0.0
2.68ArgTyr: 2.68 ± 0.549
0.0ArgXaa: 0.0 ± 0.0
Ser
3.126SerAla: 3.126 ± 1.225
0.447SerCys: 0.447 ± 0.4
6.699SerAsp: 6.699 ± 1.87
4.913SerGlu: 4.913 ± 1.535
4.02SerPhe: 4.02 ± 0.89
4.466SerGly: 4.466 ± 2.033
2.233SerHis: 2.233 ± 0.744
3.126SerIle: 3.126 ± 1.653
1.787SerLys: 1.787 ± 0.589
8.933SerLeu: 8.933 ± 2.328
0.893SerMet: 0.893 ± 0.567
2.233SerAsn: 2.233 ± 1.058
6.699SerPro: 6.699 ± 1.508
4.466SerGln: 4.466 ± 1.751
4.466SerArg: 4.466 ± 1.054
8.039SerSer: 8.039 ± 1.695
4.913SerThr: 4.913 ± 1.504
3.573SerVal: 3.573 ± 0.773
1.34SerTrp: 1.34 ± 0.412
0.893SerTyr: 0.893 ± 0.441
0.0SerXaa: 0.0 ± 0.0
Thr
4.913ThrAla: 4.913 ± 1.227
2.68ThrCys: 2.68 ± 0.927
3.126ThrAsp: 3.126 ± 1.279
2.233ThrGlu: 2.233 ± 1.196
2.68ThrPhe: 2.68 ± 0.659
6.253ThrGly: 6.253 ± 1.63
0.893ThrHis: 0.893 ± 0.415
2.233ThrIle: 2.233 ± 1.553
0.447ThrLys: 0.447 ± 0.403
3.573ThrLeu: 3.573 ± 1.157
0.893ThrMet: 0.893 ± 0.441
2.233ThrAsn: 2.233 ± 0.829
1.787ThrPro: 1.787 ± 0.266
0.447ThrGln: 0.447 ± 0.4
3.126ThrArg: 3.126 ± 1.279
4.02ThrSer: 4.02 ± 1.31
3.126ThrThr: 3.126 ± 0.565
8.486ThrVal: 8.486 ± 1.772
0.447ThrTrp: 0.447 ± 0.4
2.233ThrTyr: 2.233 ± 0.394
0.0ThrXaa: 0.0 ± 0.0
Val
2.68ValAla: 2.68 ± 0.864
1.34ValCys: 1.34 ± 1.26
7.593ValAsp: 7.593 ± 2.268
4.02ValGlu: 4.02 ± 0.759
4.466ValPhe: 4.466 ± 1.808
5.806ValGly: 5.806 ± 1.699
0.893ValHis: 0.893 ± 0.777
2.68ValIle: 2.68 ± 0.549
1.34ValLys: 1.34 ± 0.417
4.466ValLeu: 4.466 ± 1.029
0.447ValMet: 0.447 ± 0.403
2.68ValAsn: 2.68 ± 1.12
4.02ValPro: 4.02 ± 2.004
4.02ValGln: 4.02 ± 1.119
4.466ValArg: 4.466 ± 1.041
7.593ValSer: 7.593 ± 2.353
6.699ValThr: 6.699 ± 0.757
4.02ValVal: 4.02 ± 1.481
1.34ValTrp: 1.34 ± 0.779
1.787ValTyr: 1.787 ± 1.048
0.0ValXaa: 0.0 ± 0.0
Trp
0.447TrpAla: 0.447 ± 0.313
0.0TrpCys: 0.0 ± 0.0
1.34TrpAsp: 1.34 ± 0.646
0.893TrpGlu: 0.893 ± 0.471
0.893TrpPhe: 0.893 ± 0.625
2.233TrpGly: 2.233 ± 1.043
0.447TrpHis: 0.447 ± 0.4
1.34TrpIle: 1.34 ± 0.624
1.787TrpLys: 1.787 ± 0.92
1.34TrpLeu: 1.34 ± 0.785
0.0TrpMet: 0.0 ± 0.0
1.787TrpAsn: 1.787 ± 0.941
0.447TrpPro: 0.447 ± 0.388
0.0TrpGln: 0.0 ± 0.0
1.34TrpArg: 1.34 ± 1.283
1.34TrpSer: 1.34 ± 0.741
0.893TrpThr: 0.893 ± 0.471
2.233TrpVal: 2.233 ± 0.45
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.787TyrAla: 1.787 ± 1.265
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
2.233TyrGlu: 2.233 ± 0.776
1.34TyrPhe: 1.34 ± 0.881
2.233TyrGly: 2.233 ± 0.544
0.0TyrHis: 0.0 ± 0.0
0.447TyrIle: 0.447 ± 0.403
0.893TyrLys: 0.893 ± 0.441
2.233TyrLeu: 2.233 ± 0.728
0.0TyrMet: 0.0 ± 0.0
0.893TyrAsn: 0.893 ± 0.415
1.34TyrPro: 1.34 ± 0.846
2.233TyrGln: 2.233 ± 0.394
3.573TyrArg: 3.573 ± 0.606
1.787TyrSer: 1.787 ± 0.667
1.34TyrThr: 1.34 ± 2.198
3.573TyrVal: 3.573 ± 1.569
1.34TyrTrp: 1.34 ± 0.427
2.68TyrTyr: 2.68 ± 0.909
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2240 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski