Amino acid dipepetide frequency for Simian foamy virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.66AlaAla: 3.66 ± 1.025
0.845AlaCys: 0.845 ± 0.378
1.689AlaAsp: 1.689 ± 0.768
4.223AlaGlu: 4.223 ± 1.228
2.252AlaPhe: 2.252 ± 0.58
3.097AlaGly: 3.097 ± 0.546
1.971AlaHis: 1.971 ± 0.66
2.534AlaIle: 2.534 ± 1.076
2.534AlaLys: 2.534 ± 0.605
7.32AlaLeu: 7.32 ± 1.253
0.845AlaMet: 0.845 ± 0.41
3.097AlaAsn: 3.097 ± 0.599
3.378AlaPro: 3.378 ± 1.719
2.252AlaGln: 2.252 ± 0.626
2.534AlaArg: 2.534 ± 0.499
4.505AlaSer: 4.505 ± 1.085
3.941AlaThr: 3.941 ± 0.565
3.66AlaVal: 3.66 ± 1.296
0.845AlaTrp: 0.845 ± 0.661
1.689AlaTyr: 1.689 ± 0.791
0.0AlaXaa: 0.0 ± 0.0
Cys
0.845CysAla: 0.845 ± 0.404
0.563CysCys: 0.563 ± 0.391
0.845CysAsp: 0.845 ± 0.501
0.0CysGlu: 0.0 ± 0.0
1.689CysPhe: 1.689 ± 0.948
0.282CysGly: 0.282 ± 0.22
0.0CysHis: 0.0 ± 0.0
1.126CysIle: 1.126 ± 0.445
1.126CysLys: 1.126 ± 0.445
1.126CysLeu: 1.126 ± 0.318
0.0CysMet: 0.0 ± 0.0
0.845CysAsn: 0.845 ± 0.661
0.563CysPro: 0.563 ± 0.441
0.845CysGln: 0.845 ± 0.24
1.408CysArg: 1.408 ± 0.673
1.408CysSer: 1.408 ± 0.821
0.282CysThr: 0.282 ± 0.328
0.0CysVal: 0.0 ± 0.0
0.282CysTrp: 0.282 ± 0.228
0.563CysTyr: 0.563 ± 0.441
0.0CysXaa: 0.0 ± 0.0
Asp
0.563AspAla: 0.563 ± 0.455
0.845AspCys: 0.845 ± 0.661
2.534AspAsp: 2.534 ± 0.511
1.408AspGlu: 1.408 ± 0.744
0.563AspPhe: 0.563 ± 0.441
2.815AspGly: 2.815 ± 0.742
1.689AspHis: 1.689 ± 0.465
3.66AspIle: 3.66 ± 0.458
1.689AspLys: 1.689 ± 0.707
4.223AspLeu: 4.223 ± 1.112
0.0AspMet: 0.0 ± 0.0
1.689AspAsn: 1.689 ± 0.571
4.223AspPro: 4.223 ± 1.537
3.941AspGln: 3.941 ± 1.274
0.282AspArg: 0.282 ± 0.22
3.941AspSer: 3.941 ± 0.409
2.534AspThr: 2.534 ± 1.164
3.941AspVal: 3.941 ± 0.374
0.845AspTrp: 0.845 ± 0.378
2.534AspTyr: 2.534 ± 0.838
0.0AspXaa: 0.0 ± 0.0
Glu
2.534GluAla: 2.534 ± 0.297
1.689GluCys: 1.689 ± 0.463
2.534GluAsp: 2.534 ± 0.593
8.727GluGlu: 8.727 ± 2.944
1.689GluPhe: 1.689 ± 0.707
4.505GluGly: 4.505 ± 1.041
0.282GluHis: 0.282 ± 0.228
6.194GluIle: 6.194 ± 0.914
3.378GluLys: 3.378 ± 0.981
5.349GluLeu: 5.349 ± 0.439
3.097GluMet: 3.097 ± 1.153
1.408GluAsn: 1.408 ± 0.592
2.534GluPro: 2.534 ± 1.038
1.408GluGln: 1.408 ± 0.621
4.786GluArg: 4.786 ± 0.907
2.815GluSer: 2.815 ± 0.641
2.252GluThr: 2.252 ± 0.332
3.941GluVal: 3.941 ± 0.668
0.282GluTrp: 0.282 ± 0.228
0.845GluTyr: 0.845 ± 0.381
0.0GluXaa: 0.0 ± 0.0
Phe
2.534PheAla: 2.534 ± 0.805
0.282PheCys: 0.282 ± 0.22
0.563PheAsp: 0.563 ± 0.269
0.845PheGlu: 0.845 ± 0.688
0.563PhePhe: 0.563 ± 0.221
1.126PheGly: 1.126 ± 0.578
1.689PheHis: 1.689 ± 0.834
3.097PheIle: 3.097 ± 0.837
1.971PheLys: 1.971 ± 0.516
2.815PheLeu: 2.815 ± 0.621
0.282PheMet: 0.282 ± 0.413
0.563PheAsn: 0.563 ± 0.455
1.971PhePro: 1.971 ± 1.021
0.845PheGln: 0.845 ± 0.515
0.282PheArg: 0.282 ± 0.22
1.971PheSer: 1.971 ± 0.551
1.971PheThr: 1.971 ± 0.924
0.845PheVal: 0.845 ± 0.189
0.845PheTrp: 0.845 ± 0.327
1.689PheTyr: 1.689 ± 0.48
0.0PheXaa: 0.0 ± 0.0
Gly
3.097GlyAla: 3.097 ± 1.02
0.282GlyCys: 0.282 ± 0.22
3.097GlyAsp: 3.097 ± 0.914
2.815GlyGlu: 2.815 ± 1.481
2.252GlyPhe: 2.252 ± 0.872
1.689GlyGly: 1.689 ± 1.358
1.971GlyHis: 1.971 ± 0.664
5.068GlyIle: 5.068 ± 0.721
3.097GlyLys: 3.097 ± 1.007
3.097GlyLeu: 3.097 ± 0.781
1.126GlyMet: 1.126 ± 0.409
3.941GlyAsn: 3.941 ± 0.887
3.941GlyPro: 3.941 ± 1.539
3.378GlyGln: 3.378 ± 1.639
4.786GlyArg: 4.786 ± 1.913
3.097GlySer: 3.097 ± 0.803
2.252GlyThr: 2.252 ± 0.715
3.378GlyVal: 3.378 ± 1.131
0.563GlyTrp: 0.563 ± 0.395
2.815GlyTyr: 2.815 ± 0.398
0.0GlyXaa: 0.0 ± 0.0
His
0.845HisAla: 0.845 ± 0.474
0.282HisCys: 0.282 ± 0.22
0.845HisAsp: 0.845 ± 0.327
1.126HisGlu: 1.126 ± 0.617
0.0HisPhe: 0.0 ± 0.0
1.689HisGly: 1.689 ± 0.519
0.0HisHis: 0.0 ± 0.0
0.845HisIle: 0.845 ± 0.415
1.126HisLys: 1.126 ± 0.539
3.378HisLeu: 3.378 ± 0.864
1.126HisMet: 1.126 ± 0.488
1.408HisAsn: 1.408 ± 0.581
2.252HisPro: 2.252 ± 0.626
2.252HisGln: 2.252 ± 0.637
1.126HisArg: 1.126 ± 0.477
0.563HisSer: 0.563 ± 0.455
2.252HisThr: 2.252 ± 0.58
2.252HisVal: 2.252 ± 0.898
0.563HisTrp: 0.563 ± 0.455
0.845HisTyr: 0.845 ± 0.331
0.0HisXaa: 0.0 ± 0.0
Ile
3.378IleAla: 3.378 ± 1.799
1.126IleCys: 1.126 ± 0.596
3.097IleAsp: 3.097 ± 0.722
2.815IleGlu: 2.815 ± 0.97
0.563IlePhe: 0.563 ± 0.271
2.534IleGly: 2.534 ± 0.846
2.815IleHis: 2.815 ± 0.902
5.631IleIle: 5.631 ± 1.627
4.505IleLys: 4.505 ± 1.012
7.601IleLeu: 7.601 ± 0.949
0.845IleMet: 0.845 ± 0.39
3.378IleAsn: 3.378 ± 0.721
5.912IlePro: 5.912 ± 0.491
5.068IleGln: 5.068 ± 1.023
2.534IleArg: 2.534 ± 1.015
3.097IleSer: 3.097 ± 0.933
4.505IleThr: 4.505 ± 1.147
3.941IleVal: 3.941 ± 0.927
1.126IleTrp: 1.126 ± 0.481
1.971IleTyr: 1.971 ± 0.517
0.0IleXaa: 0.0 ± 0.0
Lys
4.505LysAla: 4.505 ± 1.969
1.408LysCys: 1.408 ± 0.763
2.252LysAsp: 2.252 ± 0.771
3.097LysGlu: 3.097 ± 0.693
1.408LysPhe: 1.408 ± 0.57
3.097LysGly: 3.097 ± 0.834
1.126LysHis: 1.126 ± 0.431
3.378LysIle: 3.378 ± 1.092
3.941LysLys: 3.941 ± 1.558
3.378LysLeu: 3.378 ± 0.958
0.845LysMet: 0.845 ± 0.474
4.223LysAsn: 4.223 ± 1.621
4.223LysPro: 4.223 ± 1.71
3.097LysGln: 3.097 ± 1.194
3.378LysArg: 3.378 ± 1.197
2.534LysSer: 2.534 ± 0.605
3.378LysThr: 3.378 ± 1.414
4.786LysVal: 4.786 ± 1.535
1.971LysTrp: 1.971 ± 0.588
2.252LysTyr: 2.252 ± 0.672
0.0LysXaa: 0.0 ± 0.0
Leu
6.194LeuAla: 6.194 ± 0.629
0.845LeuCys: 0.845 ± 0.66
3.941LeuAsp: 3.941 ± 0.864
4.786LeuGlu: 4.786 ± 1.293
3.097LeuPhe: 3.097 ± 0.89
6.194LeuGly: 6.194 ± 1.456
1.971LeuHis: 1.971 ± 0.608
4.505LeuIle: 4.505 ± 1.057
7.038LeuLys: 7.038 ± 2.207
7.32LeuLeu: 7.32 ± 2.602
1.408LeuMet: 1.408 ± 0.77
5.631LeuAsn: 5.631 ± 0.985
4.786LeuPro: 4.786 ± 0.785
7.883LeuGln: 7.883 ± 0.745
4.786LeuArg: 4.786 ± 1.431
5.349LeuSer: 5.349 ± 1.178
5.912LeuThr: 5.912 ± 1.412
5.349LeuVal: 5.349 ± 1.016
0.845LeuTrp: 0.845 ± 0.378
2.815LeuTyr: 2.815 ± 0.838
0.0LeuXaa: 0.0 ± 0.0
Met
1.408MetAla: 1.408 ± 0.427
0.282MetCys: 0.282 ± 0.284
1.408MetAsp: 1.408 ± 0.34
1.408MetGlu: 1.408 ± 0.476
0.282MetPhe: 0.282 ± 0.22
1.408MetGly: 1.408 ± 0.34
1.689MetHis: 1.689 ± 0.513
1.971MetIle: 1.971 ± 0.723
0.845MetLys: 0.845 ± 0.474
0.845MetLeu: 0.845 ± 0.415
0.563MetMet: 0.563 ± 0.407
0.563MetAsn: 0.563 ± 0.455
1.126MetPro: 1.126 ± 0.684
0.282MetGln: 0.282 ± 0.22
0.845MetArg: 0.845 ± 0.505
1.689MetSer: 1.689 ± 0.791
1.971MetThr: 1.971 ± 0.726
0.563MetVal: 0.563 ± 0.221
0.0MetTrp: 0.0 ± 0.0
0.563MetTyr: 0.563 ± 0.269
0.0MetXaa: 0.0 ± 0.0
Asn
3.378AsnAla: 3.378 ± 0.685
0.282AsnCys: 0.282 ± 0.328
1.408AsnAsp: 1.408 ± 0.231
3.097AsnGlu: 3.097 ± 1.033
2.815AsnPhe: 2.815 ± 0.516
1.971AsnGly: 1.971 ± 0.613
0.563AsnHis: 0.563 ± 0.221
3.097AsnIle: 3.097 ± 0.89
2.534AsnLys: 2.534 ± 0.757
4.505AsnLeu: 4.505 ± 0.323
0.845AsnMet: 0.845 ± 0.327
4.223AsnAsn: 4.223 ± 0.98
3.941AsnPro: 3.941 ± 1.796
3.66AsnGln: 3.66 ± 1.124
1.408AsnArg: 1.408 ± 0.311
5.068AsnSer: 5.068 ± 0.59
3.097AsnThr: 3.097 ± 0.47
2.252AsnVal: 2.252 ± 0.613
1.408AsnTrp: 1.408 ± 0.759
1.408AsnTyr: 1.408 ± 0.621
0.0AsnXaa: 0.0 ± 0.0
Pro
3.378ProAla: 3.378 ± 0.593
0.563ProCys: 0.563 ± 0.391
1.408ProAsp: 1.408 ± 0.818
4.786ProGlu: 4.786 ± 0.913
2.534ProPhe: 2.534 ± 1.124
3.097ProGly: 3.097 ± 1.777
2.534ProHis: 2.534 ± 0.865
5.068ProIle: 5.068 ± 1.556
3.378ProLys: 3.378 ± 1.215
6.475ProLeu: 6.475 ± 1.05
1.126ProMet: 1.126 ± 0.564
1.408ProAsn: 1.408 ± 0.363
5.349ProPro: 5.349 ± 1.462
3.378ProGln: 3.378 ± 0.405
7.32ProArg: 7.32 ± 3.269
6.475ProSer: 6.475 ± 1.902
3.941ProThr: 3.941 ± 0.681
5.631ProVal: 5.631 ± 1.076
1.689ProTrp: 1.689 ± 0.745
2.815ProTyr: 2.815 ± 0.45
0.0ProXaa: 0.0 ± 0.0
Gln
3.378GlnAla: 3.378 ± 0.452
1.126GlnCys: 1.126 ± 0.578
3.097GlnAsp: 3.097 ± 0.906
4.505GlnGlu: 4.505 ± 0.519
1.126GlnPhe: 1.126 ± 0.543
4.223GlnGly: 4.223 ± 0.91
1.971GlnHis: 1.971 ± 0.472
2.252GlnIle: 2.252 ± 0.815
3.378GlnLys: 3.378 ± 1.141
5.912GlnLeu: 5.912 ± 1.591
1.126GlnMet: 1.126 ± 0.439
3.941GlnAsn: 3.941 ± 0.937
3.378GlnPro: 3.378 ± 0.681
2.252GlnGln: 2.252 ± 0.574
2.534GlnArg: 2.534 ± 1.277
3.66GlnSer: 3.66 ± 1.648
3.378GlnThr: 3.378 ± 0.593
2.815GlnVal: 2.815 ± 0.319
0.845GlnTrp: 0.845 ± 0.378
2.815GlnTyr: 2.815 ± 0.45
0.0GlnXaa: 0.0 ± 0.0
Arg
3.66ArgAla: 3.66 ± 1.202
0.845ArgCys: 0.845 ± 0.364
1.971ArgAsp: 1.971 ± 0.853
2.815ArgGlu: 2.815 ± 0.427
0.563ArgPhe: 0.563 ± 0.271
5.349ArgGly: 5.349 ± 3.06
0.845ArgHis: 0.845 ± 0.474
2.815ArgIle: 2.815 ± 0.727
3.66ArgLys: 3.66 ± 0.856
3.097ArgLeu: 3.097 ± 0.476
0.845ArgMet: 0.845 ± 0.189
2.534ArgAsn: 2.534 ± 0.882
6.475ArgPro: 6.475 ± 2.083
1.689ArgGln: 1.689 ± 1.273
2.815ArgArg: 2.815 ± 1.078
3.66ArgSer: 3.66 ± 0.68
3.097ArgThr: 3.097 ± 0.809
2.534ArgVal: 2.534 ± 0.849
1.408ArgTrp: 1.408 ± 0.573
1.408ArgTyr: 1.408 ± 0.787
0.0ArgXaa: 0.0 ± 0.0
Ser
5.068SerAla: 5.068 ± 1.149
0.282SerCys: 0.282 ± 0.22
5.349SerAsp: 5.349 ± 1.694
3.941SerGlu: 3.941 ± 1.838
1.408SerPhe: 1.408 ± 0.231
4.223SerGly: 4.223 ± 1.478
1.126SerHis: 1.126 ± 0.318
4.223SerIle: 4.223 ± 1.304
2.534SerLys: 2.534 ± 0.98
6.194SerLeu: 6.194 ± 0.888
1.408SerMet: 1.408 ± 0.231
3.66SerAsn: 3.66 ± 1.326
5.068SerPro: 5.068 ± 1.229
3.097SerGln: 3.097 ± 0.962
3.941SerArg: 3.941 ± 1.088
7.32SerSer: 7.32 ± 1.147
4.505SerThr: 4.505 ± 0.83
2.534SerVal: 2.534 ± 0.882
1.126SerTrp: 1.126 ± 0.344
2.815SerTyr: 2.815 ± 0.538
0.0SerXaa: 0.0 ± 0.0
Thr
2.815ThrAla: 2.815 ± 0.621
1.126ThrCys: 1.126 ± 0.344
1.689ThrAsp: 1.689 ± 0.47
3.941ThrGlu: 3.941 ± 0.529
1.689ThrPhe: 1.689 ± 0.23
3.378ThrGly: 3.378 ± 0.887
1.126ThrHis: 1.126 ± 0.606
2.815ThrIle: 2.815 ± 1.416
3.66ThrLys: 3.66 ± 1.04
6.757ThrLeu: 6.757 ± 0.935
1.689ThrMet: 1.689 ± 0.403
1.126ThrAsn: 1.126 ± 0.431
5.068ThrPro: 5.068 ± 1.473
3.378ThrGln: 3.378 ± 1.191
3.941ThrArg: 3.941 ± 0.531
5.349ThrSer: 5.349 ± 0.633
2.252ThrThr: 2.252 ± 0.351
3.66ThrVal: 3.66 ± 0.757
1.689ThrTrp: 1.689 ± 0.403
2.815ThrTyr: 2.815 ± 0.833
0.0ThrXaa: 0.0 ± 0.0
Val
2.534ValAla: 2.534 ± 0.765
0.282ValCys: 0.282 ± 0.22
2.252ValAsp: 2.252 ± 0.995
2.815ValGlu: 2.815 ± 0.644
1.971ValPhe: 1.971 ± 0.512
2.815ValGly: 2.815 ± 0.768
0.282ValHis: 0.282 ± 0.22
4.786ValIle: 4.786 ± 0.635
3.941ValLys: 3.941 ± 0.857
5.912ValLeu: 5.912 ± 1.429
0.282ValMet: 0.282 ± 0.22
4.505ValAsn: 4.505 ± 0.708
4.223ValPro: 4.223 ± 0.836
4.786ValGln: 4.786 ± 0.967
1.971ValArg: 1.971 ± 0.904
3.66ValSer: 3.66 ± 0.791
4.786ValThr: 4.786 ± 1.532
5.349ValVal: 5.349 ± 1.366
1.971ValTrp: 1.971 ± 1.133
2.534ValTyr: 2.534 ± 0.381
0.0ValXaa: 0.0 ± 0.0
Trp
1.126TrpAla: 1.126 ± 0.318
0.282TrpCys: 0.282 ± 0.284
1.689TrpAsp: 1.689 ± 0.615
1.408TrpGlu: 1.408 ± 0.444
0.282TrpPhe: 0.282 ± 0.284
0.282TrpGly: 0.282 ± 0.269
0.282TrpHis: 0.282 ± 0.228
1.689TrpIle: 1.689 ± 0.611
1.408TrpLys: 1.408 ± 0.757
1.971TrpLeu: 1.971 ± 0.465
0.845TrpMet: 0.845 ± 0.378
0.845TrpAsn: 0.845 ± 0.661
1.126TrpPro: 1.126 ± 0.374
1.126TrpGln: 1.126 ± 0.318
0.563TrpArg: 0.563 ± 0.221
1.408TrpSer: 1.408 ± 0.726
1.408TrpThr: 1.408 ± 0.565
0.845TrpVal: 0.845 ± 0.66
0.845TrpTrp: 0.845 ± 0.331
0.563TrpTyr: 0.563 ± 0.221
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.971TyrAla: 1.971 ± 0.945
0.563TyrCys: 0.563 ± 0.336
2.252TyrAsp: 2.252 ± 0.637
1.689TyrGlu: 1.689 ± 0.702
0.282TyrPhe: 0.282 ± 0.22
1.971TyrGly: 1.971 ± 0.97
0.845TyrHis: 0.845 ± 0.24
1.689TyrIle: 1.689 ± 0.463
2.534TyrLys: 2.534 ± 1.437
3.378TyrLeu: 3.378 ± 1.045
1.126TyrMet: 1.126 ± 0.344
1.971TyrAsn: 1.971 ± 0.423
2.815TyrPro: 2.815 ± 1.312
3.097TyrGln: 3.097 ± 1.157
0.845TyrArg: 0.845 ± 0.331
2.252TyrSer: 2.252 ± 0.21
2.252TyrThr: 2.252 ± 0.604
3.378TyrVal: 3.378 ± 0.857
0.845TyrTrp: 0.845 ± 0.683
2.534TyrTyr: 2.534 ± 0.701
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3553 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski