Amino acid dipepetide frequency for Romboutsia ilealis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	2.89AlaAla: 2.89 ± 0.089	0.715AlaCys: 0.715 ± 0.035	2.404AlaAsp: 2.404 ± 0.123	2.76AlaGlu: 2.76 ± 0.166	2.12AlaPhe: 2.12 ± 0.061	3.339AlaGly: 3.339 ± 0.086	0.807AlaHis: 0.807 ± 0.037	5.795AlaIle: 5.795 ± 0.109	4.797AlaLys: 4.797 ± 0.091	5.175AlaLeu: 5.175 ± 0.101	1.693AlaMet: 1.693 ± 0.052	2.896AlaAsn: 2.896 ± 0.066	1.291AlaPro: 1.291 ± 0.047	1.552AlaGln: 1.552 ± 0.055	1.753AlaArg: 1.753 ± 0.056	3.224AlaSer: 3.224 ± 0.078	2.962AlaThr: 2.962 ± 0.076	3.387AlaVal: 3.387 ± 0.087	0.361AlaTrp: 0.361 ± 0.025	2.072AlaTyr: 2.072 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	0.604CysAla: 0.604 ± 0.034	0.19CysCys: 0.19 ± 0.027	0.743CysAsp: 0.743 ± 0.035	0.83CysGlu: 0.83 ± 0.037	0.391CysPhe: 0.391 ± 0.022	1.079CysGly: 1.079 ± 0.051	0.176CysHis: 0.176 ± 0.016	1.275CysIle: 1.275 ± 0.049	1.065CysLys: 1.065 ± 0.042	0.84CysLeu: 0.84 ± 0.031	0.315CysMet: 0.315 ± 0.023	0.761CysAsn: 0.761 ± 0.041	0.449CysPro: 0.449 ± 0.028	0.245CysGln: 0.245 ± 0.02	0.316CysArg: 0.316 ± 0.022	0.778CysSer: 0.778 ± 0.034	0.532CysThr: 0.532 ± 0.031	0.684CysVal: 0.684 ± 0.035	0.047CysTrp: 0.047 ± 0.009	0.426CysTyr: 0.426 ± 0.03	0.0CysXaa: 0.0 ± 0.0
Asp	2.946AspAla: 2.946 ± 0.133	0.63AspCys: 0.63 ± 0.033	3.184AspAsp: 3.184 ± 0.077	5.098AspGlu: 5.098 ± 0.093	2.666AspPhe: 2.666 ± 0.069	3.128AspGly: 3.128 ± 0.071	0.605AspHis: 0.605 ± 0.034	7.419AspIle: 7.419 ± 0.123	6.115AspLys: 6.115 ± 0.12	5.238AspLeu: 5.238 ± 0.084	1.694AspMet: 1.694 ± 0.043	3.859AspAsn: 3.859 ± 0.09	1.215AspPro: 1.215 ± 0.041	0.857AspGln: 0.857 ± 0.036	1.92AspArg: 1.92 ± 0.049	3.224AspSer: 3.224 ± 0.08	2.877AspThr: 2.877 ± 0.069	3.664AspVal: 3.664 ± 0.069	0.343AspTrp: 0.343 ± 0.025	2.862AspTyr: 2.862 ± 0.073	0.0AspXaa: 0.0 ± 0.0
Glu	3.813GluAla: 3.813 ± 0.172	0.75GluCys: 0.75 ± 0.038	4.74GluAsp: 4.74 ± 0.098	6.995GluGlu: 6.995 ± 0.127	3.068GluPhe: 3.068 ± 0.077	3.912GluGly: 3.912 ± 0.088	0.904GluHis: 0.904 ± 0.043	7.373GluIle: 7.373 ± 0.118	6.989GluLys: 6.989 ± 0.112	6.803GluLeu: 6.803 ± 0.107	1.746GluMet: 1.746 ± 0.053	6.082GluAsn: 6.082 ± 0.119	1.286GluPro: 1.286 ± 0.047	1.738GluGln: 1.738 ± 0.05	2.361GluArg: 2.361 ± 0.066	3.734GluSer: 3.734 ± 0.071	2.876GluThr: 2.876 ± 0.069	5.208GluVal: 5.208 ± 0.091	0.306GluTrp: 0.306 ± 0.021	3.375GluTyr: 3.375 ± 0.072	0.0GluXaa: 0.0 ± 0.0
Phe	2.132PheAla: 2.132 ± 0.059	0.474PheCys: 0.474 ± 0.028	2.607PheAsp: 2.607 ± 0.065	2.8PheGlu: 2.8 ± 0.066	1.625PhePhe: 1.625 ± 0.054	2.641PheGly: 2.641 ± 0.077	0.434PheHis: 0.434 ± 0.025	4.779PheIle: 4.779 ± 0.094	3.789PheLys: 3.789 ± 0.075	3.603PheLeu: 3.603 ± 0.087	1.198PheMet: 1.198 ± 0.044	3.089PheAsn: 3.089 ± 0.063	0.966PhePro: 0.966 ± 0.038	0.63PheGln: 0.63 ± 0.03	1.166PheArg: 1.166 ± 0.036	2.656PheSer: 2.656 ± 0.064	2.306PheThr: 2.306 ± 0.059	2.507PheVal: 2.507 ± 0.06	0.235PheTrp: 0.235 ± 0.018	1.633PheTyr: 1.633 ± 0.046	0.0PheXaa: 0.0 ± 0.0
Gly	3.67GlyAla: 3.67 ± 0.108	1.016GlyCys: 1.016 ± 0.046	3.018GlyAsp: 3.018 ± 0.075	3.852GlyGlu: 3.852 ± 0.082	2.769GlyPhe: 2.769 ± 0.07	3.912GlyGly: 3.912 ± 0.098	1.017GlyHis: 1.017 ± 0.046	6.655GlyIle: 6.655 ± 0.107	5.018GlyLys: 5.018 ± 0.094	5.433GlyLeu: 5.433 ± 0.091	1.811GlyMet: 1.811 ± 0.067	3.125GlyAsn: 3.125 ± 0.071	1.23GlyPro: 1.23 ± 0.061	1.484GlyGln: 1.484 ± 0.046	1.964GlyArg: 1.964 ± 0.06	3.553GlySer: 3.553 ± 0.076	3.112GlyThr: 3.112 ± 0.075	4.579GlyVal: 4.579 ± 0.106	0.399GlyTrp: 0.399 ± 0.028	3.111GlyTyr: 3.111 ± 0.074	0.001GlyXaa: 0.001 ± 0.002
His	0.64HisAla: 0.64 ± 0.031	0.193HisCys: 0.193 ± 0.017	0.703HisAsp: 0.703 ± 0.034	0.899HisGlu: 0.899 ± 0.041	0.564HisPhe: 0.564 ± 0.029	0.914HisGly: 0.914 ± 0.042	0.265HisHis: 0.265 ± 0.023	1.488HisIle: 1.488 ± 0.048	1.129HisLys: 1.129 ± 0.045	1.182HisLeu: 1.182 ± 0.042	0.356HisMet: 0.356 ± 0.022	0.847HisAsn: 0.847 ± 0.041	0.587HisPro: 0.587 ± 0.034	0.345HisGln: 0.345 ± 0.025	0.481HisArg: 0.481 ± 0.025	0.861HisSer: 0.861 ± 0.034	0.747HisThr: 0.747 ± 0.032	0.7HisVal: 0.7 ± 0.034	0.097HisTrp: 0.097 ± 0.012	0.547HisTyr: 0.547 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.61IleAla: 5.61 ± 0.11	1.326IleCys: 1.326 ± 0.042	7.168IleAsp: 7.168 ± 0.123	7.789IleGlu: 7.789 ± 0.119	4.108IlePhe: 4.108 ± 0.097	6.54IleGly: 6.54 ± 0.127	1.331IleHis: 1.331 ± 0.055	9.619IleIle: 9.619 ± 0.169	9.489IleLys: 9.489 ± 0.137	9.613IleLeu: 9.613 ± 0.165	2.321IleMet: 2.321 ± 0.06	7.433IleAsn: 7.433 ± 0.131	3.292IlePro: 3.292 ± 0.078	2.203IleGln: 2.203 ± 0.06	2.906IleArg: 2.906 ± 0.058	7.307IleSer: 7.307 ± 0.117	4.942IleThr: 4.942 ± 0.085	6.678IleVal: 6.678 ± 0.114	0.515IleTrp: 0.515 ± 0.025	3.998IleTyr: 3.998 ± 0.095	0.0IleXaa: 0.0 ± 0.0
Lys	4.324LysAla: 4.324 ± 0.076	0.867LysCys: 0.867 ± 0.039	6.406LysAsp: 6.406 ± 0.104	8.865LysGlu: 8.865 ± 0.126	3.43LysPhe: 3.43 ± 0.08	4.703LysGly: 4.703 ± 0.089	1.225LysHis: 1.225 ± 0.047	8.512LysIle: 8.512 ± 0.12	8.012LysLys: 8.012 ± 0.139	7.865LysLeu: 7.865 ± 0.112	2.57LysMet: 2.57 ± 0.06	6.984LysAsn: 6.984 ± 0.132	1.963LysPro: 1.963 ± 0.063	2.245LysGln: 2.245 ± 0.052	2.88LysArg: 2.88 ± 0.066	5.706LysSer: 5.706 ± 0.109	4.109LysThr: 4.109 ± 0.074	5.939LysVal: 5.939 ± 0.1	0.492LysTrp: 0.492 ± 0.028	4.561LysTyr: 4.561 ± 0.094	0.001LysXaa: 0.001 ± 0.001
Leu	4.918LeuAla: 4.918 ± 0.097	0.961LeuCys: 0.961 ± 0.045	6.012LeuAsp: 6.012 ± 0.114	6.76LeuGlu: 6.76 ± 0.108	3.717LeuPhe: 3.717 ± 0.096	5.988LeuGly: 5.988 ± 0.112	1.07LeuHis: 1.07 ± 0.042	8.131LeuIle: 8.131 ± 0.14	8.279LeuLys: 8.279 ± 0.132	7.706LeuLeu: 7.706 ± 0.125	2.152LeuMet: 2.152 ± 0.061	6.506LeuAsn: 6.506 ± 0.121	2.593LeuPro: 2.593 ± 0.06	2.079LeuGln: 2.079 ± 0.049	2.906LeuArg: 2.906 ± 0.07	6.532LeuSer: 6.532 ± 0.106	4.415LeuThr: 4.415 ± 0.08	5.712LeuVal: 5.712 ± 0.097	0.478LeuTrp: 0.478 ± 0.032	3.297LeuTyr: 3.297 ± 0.082	0.0LeuXaa: 0.0 ± 0.0
Met	1.691MetAla: 1.691 ± 0.053	0.283MetCys: 0.283 ± 0.017	1.508MetAsp: 1.508 ± 0.054	1.738MetGlu: 1.738 ± 0.055	1.006MetPhe: 1.006 ± 0.04	1.73MetGly: 1.73 ± 0.06	0.336MetHis: 0.336 ± 0.021	2.482MetIle: 2.482 ± 0.066	2.474MetLys: 2.474 ± 0.052	2.206MetLeu: 2.206 ± 0.063	0.78MetMet: 0.78 ± 0.042	1.8MetAsn: 1.8 ± 0.048	0.833MetPro: 0.833 ± 0.036	0.697MetGln: 0.697 ± 0.034	0.858MetArg: 0.858 ± 0.034	1.81MetSer: 1.81 ± 0.047	1.328MetThr: 1.328 ± 0.038	1.538MetVal: 1.538 ± 0.047	0.14MetTrp: 0.14 ± 0.014	1.023MetTyr: 1.023 ± 0.037	0.0MetXaa: 0.0 ± 0.0
Asn	2.92AsnAla: 2.92 ± 0.066	0.728AsnCys: 0.728 ± 0.034	3.551AsnAsp: 3.551 ± 0.074	4.896AsnGlu: 4.896 ± 0.087	2.445AsnPhe: 2.445 ± 0.064	3.504AsnGly: 3.504 ± 0.088	0.957AsnHis: 0.957 ± 0.041	8.698AsnIle: 8.698 ± 0.132	7.278AsnLys: 7.278 ± 0.127	6.572AsnLeu: 6.572 ± 0.118	1.787AsnMet: 1.787 ± 0.048	5.355AsnAsn: 5.355 ± 0.117	2.271AsnPro: 2.271 ± 0.058	1.643AsnGln: 1.643 ± 0.053	2.007AsnArg: 2.007 ± 0.06	3.799AsnSer: 3.799 ± 0.086	3.322AsnThr: 3.322 ± 0.074	3.669AsnVal: 3.669 ± 0.071	0.406AsnTrp: 0.406 ± 0.029	2.965AsnTyr: 2.965 ± 0.068	0.0AsnXaa: 0.0 ± 0.0
Pro	1.326ProAla: 1.326 ± 0.054	0.289ProCys: 0.289 ± 0.021	1.305ProAsp: 1.305 ± 0.048	1.927ProGlu: 1.927 ± 0.064	1.303ProPhe: 1.303 ± 0.044	1.52ProGly: 1.52 ± 0.055	0.469ProHis: 0.469 ± 0.028	2.85ProIle: 2.85 ± 0.068	2.326ProLys: 2.326 ± 0.056	2.153ProLeu: 2.153 ± 0.057	0.728ProMet: 0.728 ± 0.038	1.634ProAsn: 1.634 ± 0.05	0.508ProPro: 0.508 ± 0.026	0.806ProGln: 0.806 ± 0.041	0.745ProArg: 0.745 ± 0.033	1.69ProSer: 1.69 ± 0.049	1.512ProThr: 1.512 ± 0.047	1.846ProVal: 1.846 ± 0.054	0.212ProTrp: 0.212 ± 0.017	1.22ProTyr: 1.22 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	1.332GlnAla: 1.332 ± 0.055	0.229GlnCys: 0.229 ± 0.018	1.326GlnAsp: 1.326 ± 0.048	1.758GlnGlu: 1.758 ± 0.056	0.897GlnPhe: 0.897 ± 0.035	1.651GlnGly: 1.651 ± 0.054	0.279GlnHis: 0.279 ± 0.021	2.228GlnIle: 2.228 ± 0.058	2.012GlnLys: 2.012 ± 0.054	2.035GlnLeu: 2.035 ± 0.051	0.668GlnMet: 0.668 ± 0.029	1.594GlnAsn: 1.594 ± 0.043	0.595GlnPro: 0.595 ± 0.026	0.641GlnGln: 0.641 ± 0.034	0.901GlnArg: 0.901 ± 0.032	1.365GlnSer: 1.365 ± 0.041	1.116GlnThr: 1.116 ± 0.04	1.571GlnVal: 1.571 ± 0.046	0.157GlnTrp: 0.157 ± 0.017	0.983GlnTyr: 0.983 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	1.653ArgAla: 1.653 ± 0.049	0.418ArgCys: 0.418 ± 0.025	1.833ArgAsp: 1.833 ± 0.056	2.696ArgGlu: 2.696 ± 0.068	1.313ArgPhe: 1.313 ± 0.043	1.831ArgGly: 1.831 ± 0.05	0.492ArgHis: 0.492 ± 0.026	2.783ArgIle: 2.783 ± 0.067	2.896ArgLys: 2.896 ± 0.066	2.79ArgLeu: 2.79 ± 0.058	0.856ArgMet: 0.856 ± 0.036	1.956ArgAsn: 1.956 ± 0.05	0.91ArgPro: 0.91 ± 0.038	0.841ArgGln: 0.841 ± 0.033	1.316ArgArg: 1.316 ± 0.055	1.504ArgSer: 1.504 ± 0.047	1.454ArgThr: 1.454 ± 0.046	2.195ArgVal: 2.195 ± 0.062	0.219ArgTrp: 0.219 ± 0.02	1.471ArgTyr: 1.471 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	2.882SerAla: 2.882 ± 0.074	0.651SerCys: 0.651 ± 0.031	3.204SerAsp: 3.204 ± 0.071	3.743SerGlu: 3.743 ± 0.076	2.843SerPhe: 2.843 ± 0.064	3.734SerGly: 3.734 ± 0.082	0.929SerHis: 0.929 ± 0.035	7.148SerIle: 7.148 ± 0.129	6.148SerLys: 6.148 ± 0.105	5.941SerLeu: 5.941 ± 0.094	1.67SerMet: 1.67 ± 0.056	4.209SerAsn: 4.209 ± 0.087	1.472SerPro: 1.472 ± 0.047	1.788SerGln: 1.788 ± 0.052	2.035SerArg: 2.035 ± 0.06	4.159SerSer: 4.159 ± 0.095	3.365SerThr: 3.365 ± 0.081	3.706SerVal: 3.706 ± 0.074	0.353SerTrp: 0.353 ± 0.024	2.667SerTyr: 2.667 ± 0.066	0.0SerXaa: 0.0 ± 0.0
Thr	2.554ThrAla: 2.554 ± 0.068	0.507ThrCys: 0.507 ± 0.027	2.51ThrAsp: 2.51 ± 0.063	2.648ThrGlu: 2.648 ± 0.066	2.123ThrPhe: 2.123 ± 0.057	3.347ThrGly: 3.347 ± 0.076	0.783ThrHis: 0.783 ± 0.03	5.272ThrIle: 5.272 ± 0.092	3.959ThrLys: 3.959 ± 0.083	4.959ThrLeu: 4.959 ± 0.094	1.163ThrMet: 1.163 ± 0.041	3.143ThrAsn: 3.143 ± 0.071	1.737ThrPro: 1.737 ± 0.052	1.179ThrGln: 1.179 ± 0.044	1.452ThrArg: 1.452 ± 0.043	3.284ThrSer: 3.284 ± 0.074	2.849ThrThr: 2.849 ± 0.076	3.317ThrVal: 3.317 ± 0.078	0.331ThrTrp: 0.331 ± 0.025	2.085ThrTyr: 2.085 ± 0.059	0.001ThrXaa: 0.001 ± 0.002
Val	3.833ValAla: 3.833 ± 0.097	0.917ValCys: 0.917 ± 0.039	4.35ValAsp: 4.35 ± 0.082	4.478ValGlu: 4.478 ± 0.082	2.796ValPhe: 2.796 ± 0.069	4.427ValGly: 4.427 ± 0.088	0.806ValHis: 0.806 ± 0.04	6.214ValIle: 6.214 ± 0.102	5.291ValLys: 5.291 ± 0.094	5.806ValLeu: 5.806 ± 0.088	1.459ValMet: 1.459 ± 0.044	3.916ValAsn: 3.916 ± 0.083	1.843ValPro: 1.843 ± 0.058	1.279ValGln: 1.279 ± 0.043	1.9ValArg: 1.9 ± 0.052	4.318ValSer: 4.318 ± 0.08	3.025ValThr: 3.025 ± 0.071	4.757ValVal: 4.757 ± 0.088	0.333ValTrp: 0.333 ± 0.022	2.601ValTyr: 2.601 ± 0.068	0.001ValXaa: 0.001 ± 0.001
Trp	0.368TrpAla: 0.368 ± 0.025	0.076TrpCys: 0.076 ± 0.01	0.365TrpAsp: 0.365 ± 0.023	0.356TrpGlu: 0.356 ± 0.023	0.248TrpPhe: 0.248 ± 0.02	0.388TrpGly: 0.388 ± 0.03	0.096TrpHis: 0.096 ± 0.014	0.641TrpIle: 0.641 ± 0.035	0.375TrpLys: 0.375 ± 0.022	0.488TrpLeu: 0.488 ± 0.029	0.167TrpMet: 0.167 ± 0.014	0.365TrpAsn: 0.365 ± 0.024	0.119TrpPro: 0.119 ± 0.015	0.172TrpGln: 0.172 ± 0.016	0.187TrpArg: 0.187 ± 0.018	0.363TrpSer: 0.363 ± 0.024	0.249TrpThr: 0.249 ± 0.019	0.376TrpVal: 0.376 ± 0.027	0.07TrpTrp: 0.07 ± 0.011	0.252TrpTyr: 0.252 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.887TyrAla: 1.887 ± 0.045	0.524TyrCys: 0.524 ± 0.029	2.608TyrAsp: 2.608 ± 0.064	3.172TyrGlu: 3.172 ± 0.077	1.836TyrPhe: 1.836 ± 0.054	2.44TyrGly: 2.44 ± 0.06	0.562TyrHis: 0.562 ± 0.03	4.827TyrIle: 4.827 ± 0.092	4.217TyrLys: 4.217 ± 0.096	3.802TyrLeu: 3.802 ± 0.068	1.127TyrMet: 1.127 ± 0.04	3.219TyrAsn: 3.219 ± 0.062	1.212TyrPro: 1.212 ± 0.046	0.916TyrGln: 0.916 ± 0.034	1.369TyrArg: 1.369 ± 0.045	2.78TyrSer: 2.78 ± 0.08	2.103TyrThr: 2.103 ± 0.059	2.321TyrVal: 2.321 ± 0.056	0.225TyrTrp: 0.225 ± 0.018	1.817TyrTyr: 1.817 ± 0.053	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.001XaaCys: 0.001 ± 0.002	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.001	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.002	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2333 proteins (698914 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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