Amino acid dipepetide frequency for Wenzhouxiangella marina

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.77AlaAla: 12.77 ± 0.13	1.196AlaCys: 1.196 ± 0.04	6.709AlaAsp: 6.709 ± 0.079	8.347AlaGlu: 8.347 ± 0.135	3.767AlaPhe: 3.767 ± 0.067	10.241AlaGly: 10.241 ± 0.133	2.005AlaHis: 2.005 ± 0.043	5.323AlaIle: 5.323 ± 0.074	1.624AlaLys: 1.624 ± 0.05	13.932AlaLeu: 13.932 ± 0.164	2.879AlaMet: 2.879 ± 0.047	2.603AlaAsn: 2.603 ± 0.06	4.975AlaPro: 4.975 ± 0.086	3.797AlaGln: 3.797 ± 0.06	9.311AlaArg: 9.311 ± 0.128	6.903AlaSer: 6.903 ± 0.08	4.827AlaThr: 4.827 ± 0.091	7.379AlaVal: 7.379 ± 0.093	2.105AlaTrp: 2.105 ± 0.05	2.233AlaTyr: 2.233 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.807CysAla: 0.807 ± 0.028	0.102CysCys: 0.102 ± 0.012	0.524CysAsp: 0.524 ± 0.023	0.53CysGlu: 0.53 ± 0.021	0.307CysPhe: 0.307 ± 0.017	0.889CysGly: 0.889 ± 0.035	0.269CysHis: 0.269 ± 0.025	0.344CysIle: 0.344 ± 0.019	0.139CysLys: 0.139 ± 0.01	0.992CysLeu: 0.992 ± 0.029	0.15CysMet: 0.15 ± 0.011	0.261CysAsn: 0.261 ± 0.017	0.525CysPro: 0.525 ± 0.026	0.387CysGln: 0.387 ± 0.021	0.74CysArg: 0.74 ± 0.028	0.588CysSer: 0.588 ± 0.025	0.456CysThr: 0.456 ± 0.025	0.543CysVal: 0.543 ± 0.027	0.133CysTrp: 0.133 ± 0.012	0.2CysTyr: 0.2 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	6.603AspAla: 6.603 ± 0.103	0.69AspCys: 0.69 ± 0.03	3.625AspAsp: 3.625 ± 0.096	4.364AspGlu: 4.364 ± 0.065	2.582AspPhe: 2.582 ± 0.059	5.997AspGly: 5.997 ± 0.117	1.355AspHis: 1.355 ± 0.039	2.427AspIle: 2.427 ± 0.053	0.974AspLys: 0.974 ± 0.037	6.837AspLeu: 6.837 ± 0.09	1.153AspMet: 1.153 ± 0.04	1.441AspAsn: 1.441 ± 0.046	4.15AspPro: 4.15 ± 0.076	2.591AspGln: 2.591 ± 0.049	5.484AspArg: 5.484 ± 0.08	3.219AspSer: 3.219 ± 0.066	2.489AspThr: 2.489 ± 0.051	3.533AspVal: 3.533 ± 0.059	1.406AspTrp: 1.406 ± 0.04	1.72AspTyr: 1.72 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	8.75GluAla: 8.75 ± 0.143	0.43GluCys: 0.43 ± 0.019	3.583GluAsp: 3.583 ± 0.085	3.387GluGlu: 3.387 ± 0.076	2.183GluPhe: 2.183 ± 0.041	4.653GluGly: 4.653 ± 0.062	1.598GluHis: 1.598 ± 0.048	3.166GluIle: 3.166 ± 0.055	1.246GluLys: 1.246 ± 0.04	8.012GluLeu: 8.012 ± 0.106	1.242GluMet: 1.242 ± 0.038	1.495GluAsn: 1.495 ± 0.035	3.297GluPro: 3.297 ± 0.064	3.365GluGln: 3.365 ± 0.065	6.617GluArg: 6.617 ± 0.095	3.542GluSer: 3.542 ± 0.053	3.061GluThr: 3.061 ± 0.055	4.505GluVal: 4.505 ± 0.069	0.785GluTrp: 0.785 ± 0.028	1.148GluTyr: 1.148 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	3.636PheAla: 3.636 ± 0.053	0.324PheCys: 0.324 ± 0.017	2.996PheAsp: 2.996 ± 0.06	2.879PheGlu: 2.879 ± 0.052	1.394PhePhe: 1.394 ± 0.042	3.474PheGly: 3.474 ± 0.072	0.748PheHis: 0.748 ± 0.028	1.574PheIle: 1.574 ± 0.044	0.736PheLys: 0.736 ± 0.028	3.401PheLeu: 3.401 ± 0.065	0.698PheMet: 0.698 ± 0.028	1.141PheAsn: 1.141 ± 0.035	1.478PhePro: 1.478 ± 0.035	1.243PheGln: 1.243 ± 0.036	2.296PheArg: 2.296 ± 0.052	2.461PheSer: 2.461 ± 0.062	1.754PheThr: 1.754 ± 0.052	2.359PheVal: 2.359 ± 0.057	0.54PheTrp: 0.54 ± 0.023	0.844PheTyr: 0.844 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	7.837GlyAla: 7.837 ± 0.11	0.822GlyCys: 0.822 ± 0.031	4.875GlyAsp: 4.875 ± 0.079	5.549GlyGlu: 5.549 ± 0.081	3.513GlyPhe: 3.513 ± 0.072	7.196GlyGly: 7.196 ± 0.154	1.881GlyHis: 1.881 ± 0.045	3.914GlyIle: 3.914 ± 0.07	1.904GlyLys: 1.904 ± 0.051	10.265GlyLeu: 10.265 ± 0.112	1.979GlyMet: 1.979 ± 0.047	2.556GlyAsn: 2.556 ± 0.096	3.916GlyPro: 3.916 ± 0.077	4.223GlyGln: 4.223 ± 0.08	6.534GlyArg: 6.534 ± 0.101	5.468GlySer: 5.468 ± 0.111	3.996GlyThr: 3.996 ± 0.08	5.723GlyVal: 5.723 ± 0.072	1.508GlyTrp: 1.508 ± 0.04	1.881GlyTyr: 1.881 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.162HisAla: 2.162 ± 0.042	0.26HisCys: 0.26 ± 0.018	1.155HisAsp: 1.155 ± 0.038	1.254HisGlu: 1.254 ± 0.034	0.903HisPhe: 0.903 ± 0.031	1.94HisGly: 1.94 ± 0.056	0.601HisHis: 0.601 ± 0.026	0.703HisIle: 0.703 ± 0.027	0.33HisLys: 0.33 ± 0.019	2.322HisLeu: 2.322 ± 0.055	0.358HisMet: 0.358 ± 0.019	0.443HisAsn: 0.443 ± 0.021	1.538HisPro: 1.538 ± 0.039	0.792HisGln: 0.792 ± 0.031	1.889HisArg: 1.889 ± 0.047	1.011HisSer: 1.011 ± 0.032	0.74HisThr: 0.74 ± 0.029	1.24HisVal: 1.24 ± 0.038	0.468HisTrp: 0.468 ± 0.02	0.61HisTyr: 0.61 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.409IleAla: 5.409 ± 0.076	0.397IleCys: 0.397 ± 0.019	4.105IleAsp: 4.105 ± 0.065	4.489IleGlu: 4.489 ± 0.065	1.38IlePhe: 1.38 ± 0.044	4.527IleGly: 4.527 ± 0.079	1.009IleHis: 1.009 ± 0.032	1.826IleIle: 1.826 ± 0.047	0.98IleLys: 0.98 ± 0.039	4.126IleLeu: 4.126 ± 0.078	0.716IleMet: 0.716 ± 0.027	1.551IleAsn: 1.551 ± 0.036	2.118IlePro: 2.118 ± 0.039	1.628IleGln: 1.628 ± 0.036	3.396IleArg: 3.396 ± 0.068	2.734IleSer: 2.734 ± 0.057	2.28IleThr: 2.28 ± 0.062	3.217IleVal: 3.217 ± 0.062	0.554IleTrp: 0.554 ± 0.022	1.018IleTyr: 1.018 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	2.304LysAla: 2.304 ± 0.067	0.105LysCys: 0.105 ± 0.01	1.029LysAsp: 1.029 ± 0.035	0.933LysGlu: 0.933 ± 0.035	0.494LysPhe: 0.494 ± 0.026	1.283LysGly: 1.283 ± 0.044	0.458LysHis: 0.458 ± 0.021	0.862LysIle: 0.862 ± 0.031	0.694LysLys: 0.694 ± 0.058	2.137LysLeu: 2.137 ± 0.06	0.378LysMet: 0.378 ± 0.017	0.456LysAsn: 0.456 ± 0.022	1.161LysPro: 1.161 ± 0.041	0.763LysGln: 0.763 ± 0.025	1.782LysArg: 1.782 ± 0.046	1.042LysSer: 1.042 ± 0.038	1.014LysThr: 1.014 ± 0.03	1.404LysVal: 1.404 ± 0.045	0.176LysTrp: 0.176 ± 0.012	0.399LysTyr: 0.399 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	15.005LeuAla: 15.005 ± 0.152	0.911LeuCys: 0.911 ± 0.029	8.128LeuAsp: 8.128 ± 0.1	7.526LeuGlu: 7.526 ± 0.107	3.686LeuPhe: 3.686 ± 0.067	9.138LeuGly: 9.138 ± 0.114	2.06LeuHis: 2.06 ± 0.048	6.101LeuIle: 6.101 ± 0.091	2.686LeuLys: 2.686 ± 0.071	12.028LeuLeu: 12.028 ± 0.183	2.429LeuMet: 2.429 ± 0.05	2.876LeuAsn: 2.876 ± 0.051	6.077LeuPro: 6.077 ± 0.088	3.26LeuGln: 3.26 ± 0.066	7.723LeuArg: 7.723 ± 0.101	7.334LeuSer: 7.334 ± 0.089	5.036LeuThr: 5.036 ± 0.073	7.964LeuVal: 7.964 ± 0.091	1.362LeuTrp: 1.362 ± 0.042	2.063LeuTyr: 2.063 ± 0.049	0.0LeuXaa: 0.0 ± 0.0
Met	2.621MetAla: 2.621 ± 0.054	0.099MetCys: 0.099 ± 0.011	1.182MetAsp: 1.182 ± 0.033	1.059MetGlu: 1.059 ± 0.033	0.594MetPhe: 0.594 ± 0.029	1.578MetGly: 1.578 ± 0.042	0.435MetHis: 0.435 ± 0.021	1.133MetIle: 1.133 ± 0.031	0.677MetLys: 0.677 ± 0.026	2.28MetLeu: 2.28 ± 0.049	0.465MetMet: 0.465 ± 0.022	0.798MetAsn: 0.798 ± 0.025	1.135MetPro: 1.135 ± 0.037	0.803MetGln: 0.803 ± 0.026	1.537MetArg: 1.537 ± 0.038	1.614MetSer: 1.614 ± 0.037	1.228MetThr: 1.228 ± 0.034	1.397MetVal: 1.397 ± 0.039	0.162MetTrp: 0.162 ± 0.012	0.267MetTyr: 0.267 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.76AsnAla: 2.76 ± 0.064	0.238AsnCys: 0.238 ± 0.016	1.64AsnAsp: 1.64 ± 0.052	1.541AsnGlu: 1.541 ± 0.037	0.941AsnPhe: 0.941 ± 0.032	2.548AsnGly: 2.548 ± 0.078	0.5AsnHis: 0.5 ± 0.023	1.056AsnIle: 1.056 ± 0.034	0.422AsnLys: 0.422 ± 0.023	2.896AsnLeu: 2.896 ± 0.058	0.445AsnMet: 0.445 ± 0.021	0.896AsnAsn: 0.896 ± 0.041	1.867AsnPro: 1.867 ± 0.046	1.055AsnGln: 1.055 ± 0.03	1.927AsnArg: 1.927 ± 0.042	1.402AsnSer: 1.402 ± 0.052	1.305AsnThr: 1.305 ± 0.042	1.79AsnVal: 1.79 ± 0.048	0.47AsnTrp: 0.47 ± 0.024	0.678AsnTyr: 0.678 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	6.061ProAla: 6.061 ± 0.088	0.349ProCys: 0.349 ± 0.02	4.17ProAsp: 4.17 ± 0.075	4.616ProGlu: 4.616 ± 0.064	1.681ProPhe: 1.681 ± 0.044	5.377ProGly: 5.377 ± 0.092	0.848ProHis: 0.848 ± 0.027	2.283ProIle: 2.283 ± 0.046	0.913ProLys: 0.913 ± 0.033	4.899ProLeu: 4.899 ± 0.073	1.212ProMet: 1.212 ± 0.033	1.317ProAsn: 1.317 ± 0.038	2.698ProPro: 2.698 ± 0.063	1.414ProGln: 1.414 ± 0.035	2.981ProArg: 2.981 ± 0.051	3.056ProSer: 3.056 ± 0.058	2.369ProThr: 2.369 ± 0.06	4.15ProVal: 4.15 ± 0.065	0.817ProTrp: 0.817 ± 0.028	0.956ProTyr: 0.956 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	5.69GlnAla: 5.69 ± 0.083	0.274GlnCys: 0.274 ± 0.016	1.842GlnAsp: 1.842 ± 0.039	1.483GlnGlu: 1.483 ± 0.039	1.248GlnPhe: 1.248 ± 0.037	3.022GlnGly: 3.022 ± 0.057	0.761GlnHis: 0.761 ± 0.029	1.806GlnIle: 1.806 ± 0.039	0.615GlnLys: 0.615 ± 0.023	4.027GlnLeu: 4.027 ± 0.061	0.718GlnMet: 0.718 ± 0.025	0.807GlnAsn: 0.807 ± 0.028	2.11GlnPro: 2.11 ± 0.049	1.52GlnGln: 1.52 ± 0.042	3.552GlnArg: 3.552 ± 0.063	2.149GlnSer: 2.149 ± 0.048	1.806GlnThr: 1.806 ± 0.048	2.943GlnVal: 2.943 ± 0.046	0.624GlnTrp: 0.624 ± 0.025	0.654GlnTyr: 0.654 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	8.092ArgAla: 8.092 ± 0.112	0.672ArgCys: 0.672 ± 0.029	4.155ArgAsp: 4.155 ± 0.059	4.942ArgGlu: 4.942 ± 0.094	3.544ArgPhe: 3.544 ± 0.056	4.954ArgGly: 4.954 ± 0.078	1.87ArgHis: 1.87 ± 0.044	4.442ArgIle: 4.442 ± 0.077	1.547ArgLys: 1.547 ± 0.045	10.259ArgLeu: 10.259 ± 0.134	1.809ArgMet: 1.809 ± 0.042	1.873ArgAsn: 1.873 ± 0.044	3.813ArgPro: 3.813 ± 0.072	3.483ArgGln: 3.483 ± 0.068	6.543ArgArg: 6.543 ± 0.113	4.424ArgSer: 4.424 ± 0.075	2.838ArgThr: 2.838 ± 0.052	5.472ArgVal: 5.472 ± 0.088	1.426ArgTrp: 1.426 ± 0.038	2.114ArgTyr: 2.114 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	6.488SerAla: 6.488 ± 0.085	0.626SerCys: 0.626 ± 0.034	3.662SerAsp: 3.662 ± 0.071	3.78SerGlu: 3.78 ± 0.058	2.126SerPhe: 2.126 ± 0.055	6.213SerGly: 6.213 ± 0.112	1.096SerHis: 1.096 ± 0.033	2.908SerIle: 2.908 ± 0.056	1.021SerLys: 1.021 ± 0.036	6.578SerLeu: 6.578 ± 0.087	1.307SerMet: 1.307 ± 0.037	1.816SerAsn: 1.816 ± 0.056	3.132SerPro: 3.132 ± 0.062	1.947SerGln: 1.947 ± 0.045	4.113SerArg: 4.113 ± 0.067	3.807SerSer: 3.807 ± 0.079	2.922SerThr: 2.922 ± 0.073	3.997SerVal: 3.997 ± 0.071	0.94SerTrp: 0.94 ± 0.029	1.29SerTyr: 1.29 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	5.073ThrAla: 5.073 ± 0.086	0.391ThrCys: 0.391 ± 0.02	2.589ThrAsp: 2.589 ± 0.055	2.641ThrGlu: 2.641 ± 0.048	1.372ThrPhe: 1.372 ± 0.042	4.702ThrGly: 4.702 ± 0.087	0.931ThrHis: 0.931 ± 0.026	2.429ThrIle: 2.429 ± 0.067	0.53ThrLys: 0.53 ± 0.023	5.562ThrLeu: 5.562 ± 0.087	0.824ThrMet: 0.824 ± 0.025	1.122ThrAsn: 1.122 ± 0.039	2.871ThrPro: 2.871 ± 0.057	1.281ThrGln: 1.281 ± 0.036	3.386ThrArg: 3.386 ± 0.061	2.5ThrSer: 2.5 ± 0.06	2.292ThrThr: 2.292 ± 0.074	3.849ThrVal: 3.849 ± 0.099	0.635ThrTrp: 0.635 ± 0.026	0.902ThrTyr: 0.902 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	7.509ValAla: 7.509 ± 0.096	0.624ValCys: 0.624 ± 0.025	4.83ValAsp: 4.83 ± 0.068	4.897ValGlu: 4.897 ± 0.077	2.718ValPhe: 2.718 ± 0.055	5.169ValGly: 5.169 ± 0.083	1.465ValHis: 1.465 ± 0.043	3.607ValIle: 3.607 ± 0.06	1.166ValLys: 1.166 ± 0.039	7.94ValLeu: 7.94 ± 0.099	1.536ValMet: 1.536 ± 0.042	1.911ValAsn: 1.911 ± 0.047	3.314ValPro: 3.314 ± 0.059	2.224ValGln: 2.224 ± 0.042	4.853ValArg: 4.853 ± 0.072	4.151ValSer: 4.151 ± 0.078	3.564ValThr: 3.564 ± 0.079	5.348ValVal: 5.348 ± 0.082	0.944ValTrp: 0.944 ± 0.032	1.492ValTyr: 1.492 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	1.301TrpAla: 1.301 ± 0.043	0.154TrpCys: 0.154 ± 0.012	0.635TrpAsp: 0.635 ± 0.026	0.617TrpGlu: 0.617 ± 0.025	0.671TrpPhe: 0.671 ± 0.025	0.876TrpGly: 0.876 ± 0.031	0.36TrpHis: 0.36 ± 0.019	0.816TrpIle: 0.816 ± 0.029	0.304TrpLys: 0.304 ± 0.018	2.4TrpLeu: 2.4 ± 0.062	0.424TrpMet: 0.424 ± 0.017	0.439TrpAsn: 0.439 ± 0.019	0.891TrpPro: 0.891 ± 0.031	0.903TrpGln: 0.903 ± 0.03	1.37TrpArg: 1.37 ± 0.038	1.038TrpSer: 1.038 ± 0.031	0.865TrpThr: 0.865 ± 0.032	1.028TrpVal: 1.028 ± 0.035	0.299TrpTrp: 0.299 ± 0.019	0.335TrpTyr: 0.335 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.052TyrAla: 2.052 ± 0.047	0.223TyrCys: 0.223 ± 0.014	1.207TyrAsp: 1.207 ± 0.039	1.229TyrGlu: 1.229 ± 0.037	0.873TyrPhe: 0.873 ± 0.029	1.762TyrGly: 1.762 ± 0.043	0.469TyrHis: 0.469 ± 0.024	0.74TyrIle: 0.74 ± 0.028	0.365TyrLys: 0.365 ± 0.02	2.499TyrLeu: 2.499 ± 0.054	0.342TyrMet: 0.342 ± 0.021	0.575TyrAsn: 0.575 ± 0.026	1.099TyrPro: 1.099 ± 0.035	0.973TyrGln: 0.973 ± 0.029	2.237TyrArg: 2.237 ± 0.048	1.325TyrSer: 1.325 ± 0.039	1.038TyrThr: 1.038 ± 0.034	1.422TyrVal: 1.422 ± 0.039	0.373TyrTrp: 0.373 ± 0.021	0.546TyrTyr: 0.546 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3023 proteins (1100236 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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