Amino acid dipepetide frequency for Gracilibacillus dipsosauri

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.444AlaAla: 4.444 ± 0.08	0.583AlaCys: 0.583 ± 0.023	3.154AlaAsp: 3.154 ± 0.048	4.25AlaGlu: 4.25 ± 0.066	3.152AlaPhe: 3.152 ± 0.05	4.536AlaGly: 4.536 ± 0.069	1.186AlaHis: 1.186 ± 0.03	6.168AlaIle: 6.168 ± 0.092	4.638AlaLys: 4.638 ± 0.063	6.615AlaLeu: 6.615 ± 0.086	1.951AlaMet: 1.951 ± 0.048	2.979AlaAsn: 2.979 ± 0.044	1.882AlaPro: 1.882 ± 0.046	2.095AlaGln: 2.095 ± 0.044	2.375AlaArg: 2.375 ± 0.052	3.952AlaSer: 3.952 ± 0.062	3.625AlaThr: 3.625 ± 0.06	4.474AlaVal: 4.474 ± 0.067	0.689AlaTrp: 0.689 ± 0.027	2.382AlaTyr: 2.382 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.347CysAla: 0.347 ± 0.018	0.081CysCys: 0.081 ± 0.009	0.321CysAsp: 0.321 ± 0.015	0.406CysGlu: 0.406 ± 0.02	0.306CysPhe: 0.306 ± 0.015	0.591CysGly: 0.591 ± 0.03	0.204CysHis: 0.204 ± 0.013	0.487CysIle: 0.487 ± 0.021	0.324CysLys: 0.324 ± 0.017	0.706CysLeu: 0.706 ± 0.024	0.197CysMet: 0.197 ± 0.012	0.277CysAsn: 0.277 ± 0.014	0.308CysPro: 0.308 ± 0.019	0.249CysGln: 0.249 ± 0.014	0.266CysArg: 0.266 ± 0.015	0.475CysSer: 0.475 ± 0.019	0.322CysThr: 0.322 ± 0.017	0.36CysVal: 0.36 ± 0.017	0.074CysTrp: 0.074 ± 0.007	0.268CysTyr: 0.268 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.103AspAla: 3.103 ± 0.05	0.344AspCys: 0.344 ± 0.018	2.603AspAsp: 2.603 ± 0.057	4.117AspGlu: 4.117 ± 0.065	2.491AspPhe: 2.491 ± 0.04	3.664AspGly: 3.664 ± 0.072	1.379AspHis: 1.379 ± 0.04	4.343AspIle: 4.343 ± 0.059	3.554AspLys: 3.554 ± 0.061	5.078AspLeu: 5.078 ± 0.065	1.298AspMet: 1.298 ± 0.035	2.258AspAsn: 2.258 ± 0.046	2.242AspPro: 2.242 ± 0.054	2.686AspGln: 2.686 ± 0.057	2.306AspArg: 2.306 ± 0.043	2.755AspSer: 2.755 ± 0.051	2.55AspThr: 2.55 ± 0.054	3.496AspVal: 3.496 ± 0.052	0.828AspTrp: 0.828 ± 0.028	2.373AspTyr: 2.373 ± 0.051	0.0AspXaa: 0.0 ± 0.0
Glu	5.341GluAla: 5.341 ± 0.069	0.309GluCys: 0.309 ± 0.016	4.194GluAsp: 4.194 ± 0.061	7.769GluGlu: 7.769 ± 0.114	2.472GluPhe: 2.472 ± 0.044	4.239GluGly: 4.239 ± 0.079	1.538GluHis: 1.538 ± 0.039	5.894GluIle: 5.894 ± 0.071	6.789GluLys: 6.789 ± 0.083	7.005GluLeu: 7.005 ± 0.084	2.368GluMet: 2.368 ± 0.047	4.12GluAsn: 4.12 ± 0.065	2.006GluPro: 2.006 ± 0.046	3.684GluGln: 3.684 ± 0.063	3.133GluArg: 3.133 ± 0.055	3.568GluSer: 3.568 ± 0.054	3.635GluThr: 3.635 ± 0.057	5.042GluVal: 5.042 ± 0.075	0.975GluTrp: 0.975 ± 0.031	2.277GluTyr: 2.277 ± 0.049	0.0GluXaa: 0.0 ± 0.0
Phe	2.868PheAla: 2.868 ± 0.059	0.355PheCys: 0.355 ± 0.016	2.502PheAsp: 2.502 ± 0.048	2.743PheGlu: 2.743 ± 0.05	2.448PhePhe: 2.448 ± 0.056	3.142PheGly: 3.142 ± 0.058	1.173PheHis: 1.173 ± 0.033	4.192PheIle: 4.192 ± 0.074	2.237PheLys: 2.237 ± 0.038	4.72PheLeu: 4.72 ± 0.088	1.227PheMet: 1.227 ± 0.032	1.78PheAsn: 1.78 ± 0.042	1.641PhePro: 1.641 ± 0.033	1.964PheGln: 1.964 ± 0.042	1.624PheArg: 1.624 ± 0.04	3.19PheSer: 3.19 ± 0.055	2.754PheThr: 2.754 ± 0.051	3.058PheVal: 3.058 ± 0.052	0.55PheTrp: 0.55 ± 0.023	1.861PheTyr: 1.861 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	4.255GlyAla: 4.255 ± 0.072	0.53GlyCys: 0.53 ± 0.023	3.269GlyAsp: 3.269 ± 0.067	4.489GlyGlu: 4.489 ± 0.073	3.318GlyPhe: 3.318 ± 0.06	4.455GlyGly: 4.455 ± 0.071	1.232GlyHis: 1.232 ± 0.034	5.809GlyIle: 5.809 ± 0.082	4.618GlyLys: 4.618 ± 0.066	6.346GlyLeu: 6.346 ± 0.079	2.114GlyMet: 2.114 ± 0.044	2.782GlyAsn: 2.782 ± 0.053	1.665GlyPro: 1.665 ± 0.042	1.988GlyGln: 1.988 ± 0.045	2.211GlyArg: 2.211 ± 0.052	3.779GlySer: 3.779 ± 0.06	3.717GlyThr: 3.717 ± 0.061	4.662GlyVal: 4.662 ± 0.068	0.833GlyTrp: 0.833 ± 0.034	2.772GlyTyr: 2.772 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	1.334HisAla: 1.334 ± 0.035	0.201HisCys: 0.201 ± 0.013	1.09HisAsp: 1.09 ± 0.032	1.36HisGlu: 1.36 ± 0.037	1.225HisPhe: 1.225 ± 0.03	1.375HisGly: 1.375 ± 0.034	0.833HisHis: 0.833 ± 0.035	1.642HisIle: 1.642 ± 0.038	0.987HisLys: 0.987 ± 0.028	2.354HisLeu: 2.354 ± 0.048	0.488HisMet: 0.488 ± 0.019	0.805HisAsn: 0.805 ± 0.025	1.145HisPro: 1.145 ± 0.037	1.105HisGln: 1.105 ± 0.03	0.835HisArg: 0.835 ± 0.023	1.279HisSer: 1.279 ± 0.033	1.113HisThr: 1.113 ± 0.03	1.355HisVal: 1.355 ± 0.032	0.244HisTrp: 0.244 ± 0.015	1.074HisTyr: 1.074 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	6.131IleAla: 6.131 ± 0.082	0.651IleCys: 0.651 ± 0.025	4.798IleAsp: 4.798 ± 0.06	5.987IleGlu: 5.987 ± 0.072	3.604IlePhe: 3.604 ± 0.072	6.121IleGly: 6.121 ± 0.091	1.96IleHis: 1.96 ± 0.041	6.548IleIle: 6.548 ± 0.107	4.708IleLys: 4.708 ± 0.06	7.667IleLeu: 7.667 ± 0.092	1.886IleMet: 1.886 ± 0.044	3.554IleAsn: 3.554 ± 0.061	3.573IlePro: 3.573 ± 0.06	3.295IleGln: 3.295 ± 0.058	3.073IleArg: 3.073 ± 0.047	5.233IleSer: 5.233 ± 0.068	4.795IleThr: 4.795 ± 0.065	5.527IleVal: 5.527 ± 0.074	0.842IleTrp: 0.842 ± 0.028	2.805IleTyr: 2.805 ± 0.049	0.0IleXaa: 0.0 ± 0.0
Lys	4.374LysAla: 4.374 ± 0.069	0.29LysCys: 0.29 ± 0.017	3.835LysAsp: 3.835 ± 0.064	7.026LysGlu: 7.026 ± 0.096	1.834LysPhe: 1.834 ± 0.041	4.173LysGly: 4.173 ± 0.063	1.427LysHis: 1.427 ± 0.038	4.855LysIle: 4.855 ± 0.075	5.954LysLys: 5.954 ± 0.083	5.728LysLeu: 5.728 ± 0.082	2.066LysMet: 2.066 ± 0.044	3.391LysAsn: 3.391 ± 0.054	2.07LysPro: 2.07 ± 0.045	3.549LysGln: 3.549 ± 0.061	3.119LysArg: 3.119 ± 0.058	3.403LysSer: 3.403 ± 0.054	3.241LysThr: 3.241 ± 0.054	4.5LysVal: 4.5 ± 0.061	0.977LysTrp: 0.977 ± 0.03	2.269LysTyr: 2.269 ± 0.044	0.0LysXaa: 0.0 ± 0.0
Leu	6.977LeuAla: 6.977 ± 0.088	0.615LeuCys: 0.615 ± 0.022	5.177LeuAsp: 5.177 ± 0.059	7.118LeuGlu: 7.118 ± 0.093	5.027LeuPhe: 5.027 ± 0.08	5.824LeuGly: 5.824 ± 0.08	2.017LeuHis: 2.017 ± 0.04	7.58LeuIle: 7.58 ± 0.103	6.248LeuLys: 6.248 ± 0.082	10.319LeuLeu: 10.319 ± 0.146	2.524LeuMet: 2.524 ± 0.041	4.191LeuAsn: 4.191 ± 0.063	3.999LeuPro: 3.999 ± 0.06	3.662LeuGln: 3.662 ± 0.059	3.448LeuArg: 3.448 ± 0.056	6.692LeuSer: 6.692 ± 0.089	5.627LeuThr: 5.627 ± 0.064	5.948LeuVal: 5.948 ± 0.079	0.943LeuTrp: 0.943 ± 0.031	3.327LeuTyr: 3.327 ± 0.058	0.0LeuXaa: 0.0 ± 0.0
Met	1.889MetAla: 1.889 ± 0.04	0.111MetCys: 0.111 ± 0.008	1.621MetAsp: 1.621 ± 0.034	2.242MetGlu: 2.242 ± 0.045	1.124MetPhe: 1.124 ± 0.032	1.601MetGly: 1.601 ± 0.038	0.408MetHis: 0.408 ± 0.02	2.33MetIle: 2.33 ± 0.05	2.424MetLys: 2.424 ± 0.041	2.504MetLeu: 2.504 ± 0.04	0.829MetMet: 0.829 ± 0.03	1.544MetAsn: 1.544 ± 0.039	0.955MetPro: 0.955 ± 0.033	0.953MetGln: 0.953 ± 0.03	1.024MetArg: 1.024 ± 0.028	1.511MetSer: 1.511 ± 0.04	1.574MetThr: 1.574 ± 0.035	1.878MetVal: 1.878 ± 0.043	0.223MetTrp: 0.223 ± 0.014	0.772MetTyr: 0.772 ± 0.03	0.0MetXaa: 0.0 ± 0.0
Asn	2.74AsnAla: 2.74 ± 0.049	0.281AsnCys: 0.281 ± 0.018	2.46AsnAsp: 2.46 ± 0.054	3.578AsnGlu: 3.578 ± 0.059	1.717AsnPhe: 1.717 ± 0.036	3.439AsnGly: 3.439 ± 0.06	1.235AsnHis: 1.235 ± 0.034	3.734AsnIle: 3.734 ± 0.061	3.18AsnLys: 3.18 ± 0.066	3.842AsnLeu: 3.842 ± 0.058	1.181AsnMet: 1.181 ± 0.037	2.263AsnAsn: 2.263 ± 0.056	2.138AsnPro: 2.138 ± 0.041	2.532AsnGln: 2.532 ± 0.047	2.112AsnArg: 2.112 ± 0.044	2.445AsnSer: 2.445 ± 0.052	2.282AsnThr: 2.282 ± 0.057	2.932AsnVal: 2.932 ± 0.045	0.708AsnTrp: 0.708 ± 0.027	1.873AsnTyr: 1.873 ± 0.043	0.0AsnXaa: 0.0 ± 0.0
Pro	2.14ProAla: 2.14 ± 0.041	0.195ProCys: 0.195 ± 0.012	2.032ProAsp: 2.032 ± 0.046	2.955ProGlu: 2.955 ± 0.063	1.984ProPhe: 1.984 ± 0.041	2.073ProGly: 2.073 ± 0.043	0.794ProHis: 0.794 ± 0.029	3.17ProIle: 3.17 ± 0.057	2.154ProLys: 2.154 ± 0.045	3.416ProLeu: 3.416 ± 0.054	0.852ProMet: 0.852 ± 0.028	1.959ProAsn: 1.959 ± 0.045	0.949ProPro: 0.949 ± 0.032	1.039ProGln: 1.039 ± 0.033	1.008ProArg: 1.008 ± 0.03	2.365ProSer: 2.365 ± 0.048	2.001ProThr: 2.001 ± 0.041	2.527ProVal: 2.527 ± 0.045	0.413ProTrp: 0.413 ± 0.021	1.415ProTyr: 1.415 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	2.949GlnAla: 2.949 ± 0.055	0.196GlnCys: 0.196 ± 0.014	1.956GlnAsp: 1.956 ± 0.047	3.206GlnGlu: 3.206 ± 0.057	1.798GlnPhe: 1.798 ± 0.042	2.139GlnGly: 2.139 ± 0.043	0.889GlnHis: 0.889 ± 0.028	3.084GlnIle: 3.084 ± 0.056	2.922GlnLys: 2.922 ± 0.055	4.583GlnLeu: 4.583 ± 0.064	1.173GlnMet: 1.173 ± 0.032	1.904GlnAsn: 1.904 ± 0.041	1.274GlnPro: 1.274 ± 0.033	2.065GlnGln: 2.065 ± 0.046	1.44GlnArg: 1.44 ± 0.04	2.416GlnSer: 2.416 ± 0.057	2.233GlnThr: 2.233 ± 0.043	2.487GlnVal: 2.487 ± 0.049	0.509GlnTrp: 0.509 ± 0.022	1.646GlnTyr: 1.646 ± 0.042	0.0GlnXaa: 0.0 ± 0.0
Arg	2.126ArgAla: 2.126 ± 0.043	0.209ArgCys: 0.209 ± 0.013	1.944ArgAsp: 1.944 ± 0.039	3.04ArgGlu: 3.04 ± 0.056	1.826ArgPhe: 1.826 ± 0.04	2.095ArgGly: 2.095 ± 0.049	0.738ArgHis: 0.738 ± 0.026	3.154ArgIle: 3.154 ± 0.051	3.105ArgLys: 3.105 ± 0.054	3.8ArgLeu: 3.8 ± 0.062	1.22ArgMet: 1.22 ± 0.036	1.916ArgAsn: 1.916 ± 0.039	1.164ArgPro: 1.164 ± 0.033	1.485ArgGln: 1.485 ± 0.037	1.685ArgArg: 1.685 ± 0.04	2.142ArgSer: 2.142 ± 0.049	1.933ArgThr: 1.933 ± 0.044	2.45ArgVal: 2.45 ± 0.045	0.431ArgTrp: 0.431 ± 0.021	1.555ArgTyr: 1.555 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	3.305SerAla: 3.305 ± 0.054	0.366SerCys: 0.366 ± 0.017	3.068SerAsp: 3.068 ± 0.053	3.976SerGlu: 3.976 ± 0.058	3.395SerPhe: 3.395 ± 0.061	4.018SerGly: 4.018 ± 0.058	1.218SerHis: 1.218 ± 0.032	5.436SerIle: 5.436 ± 0.074	3.748SerLys: 3.748 ± 0.059	5.992SerLeu: 5.992 ± 0.087	1.748SerMet: 1.748 ± 0.037	2.839SerAsn: 2.839 ± 0.05	1.994SerPro: 1.994 ± 0.047	1.98SerGln: 1.98 ± 0.042	2.11SerArg: 2.11 ± 0.046	3.887SerSer: 3.887 ± 0.066	3.313SerThr: 3.313 ± 0.058	3.881SerVal: 3.881 ± 0.061	0.718SerTrp: 0.718 ± 0.027	2.414SerTyr: 2.414 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	3.611ThrAla: 3.611 ± 0.054	0.377ThrCys: 0.377 ± 0.019	2.944ThrAsp: 2.944 ± 0.061	3.726ThrGlu: 3.726 ± 0.053	2.685ThrPhe: 2.685 ± 0.05	3.894ThrGly: 3.894 ± 0.057	0.982ThrHis: 0.982 ± 0.03	5.094ThrIle: 5.094 ± 0.067	3.381ThrLys: 3.381 ± 0.053	5.096ThrLeu: 5.096 ± 0.072	1.345ThrMet: 1.345 ± 0.033	2.841ThrAsn: 2.841 ± 0.05	2.181ThrPro: 2.181 ± 0.043	1.472ThrGln: 1.472 ± 0.035	1.706ThrArg: 1.706 ± 0.041	3.377ThrSer: 3.377 ± 0.053	3.118ThrThr: 3.118 ± 0.051	3.928ThrVal: 3.928 ± 0.068	0.582ThrTrp: 0.582 ± 0.025	2.006ThrTyr: 2.006 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	4.528ValAla: 4.528 ± 0.065	0.506ValCys: 0.506 ± 0.021	3.808ValAsp: 3.808 ± 0.062	5.03ValGlu: 5.03 ± 0.071	3.059ValPhe: 3.059 ± 0.051	4.235ValGly: 4.235 ± 0.066	1.318ValHis: 1.318 ± 0.035	5.595ValIle: 5.595 ± 0.079	4.204ValLys: 4.204 ± 0.069	6.298ValLeu: 6.298 ± 0.081	1.778ValMet: 1.778 ± 0.04	3.014ValAsn: 3.014 ± 0.048	2.34ValPro: 2.34 ± 0.044	2.319ValGln: 2.319 ± 0.044	2.337ValArg: 2.337 ± 0.046	4.101ValSer: 4.101 ± 0.065	3.953ValThr: 3.953 ± 0.059	4.628ValVal: 4.628 ± 0.077	0.686ValTrp: 0.686 ± 0.025	2.312ValTyr: 2.312 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	0.583TrpAla: 0.583 ± 0.024	0.088TrpCys: 0.088 ± 0.008	0.626TrpAsp: 0.626 ± 0.028	0.817TrpGlu: 0.817 ± 0.031	0.562TrpPhe: 0.562 ± 0.021	0.748TrpGly: 0.748 ± 0.028	0.263TrpHis: 0.263 ± 0.018	0.995TrpIle: 0.995 ± 0.032	0.903TrpLys: 0.903 ± 0.028	1.299TrpLeu: 1.299 ± 0.035	0.397TrpMet: 0.397 ± 0.016	0.678TrpAsn: 0.678 ± 0.026	0.31TrpPro: 0.31 ± 0.018	0.527TrpGln: 0.527 ± 0.022	0.492TrpArg: 0.492 ± 0.02	0.69TrpSer: 0.69 ± 0.027	0.621TrpThr: 0.621 ± 0.025	0.665TrpVal: 0.665 ± 0.026	0.179TrpTrp: 0.179 ± 0.013	0.433TrpTyr: 0.433 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.082TyrAla: 2.082 ± 0.042	0.28TyrCys: 0.28 ± 0.015	2.066TyrAsp: 2.066 ± 0.046	2.523TyrGlu: 2.523 ± 0.043	2.004TyrPhe: 2.004 ± 0.043	2.482TyrGly: 2.482 ± 0.049	1.052TyrHis: 1.052 ± 0.035	2.647TyrIle: 2.647 ± 0.054	2.002TyrLys: 2.002 ± 0.044	3.894TyrLeu: 3.894 ± 0.06	0.872TyrMet: 0.872 ± 0.027	1.579TyrAsn: 1.579 ± 0.039	1.607TyrPro: 1.607 ± 0.038	2.222TyrGln: 2.222 ± 0.052	1.713TyrArg: 1.713 ± 0.037	2.144TyrSer: 2.144 ± 0.042	1.941TyrThr: 1.941 ± 0.042	2.253TyrVal: 2.253 ± 0.039	0.471TyrTrp: 0.471 ± 0.022	1.633TyrTyr: 1.633 ± 0.041	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3941 proteins (1208377 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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