Amino acid dipepetide frequency for Xingshan nematode virus 5

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.566AlaAla: 10.566 ± 7.669
1.509AlaCys: 1.509 ± 0.7
0.755AlaAsp: 0.755 ± 0.577
8.302AlaGlu: 8.302 ± 2.012
0.0AlaPhe: 0.0 ± 0.0
10.566AlaGly: 10.566 ± 1.374
0.755AlaHis: 0.755 ± 0.611
1.509AlaIle: 1.509 ± 0.718
1.509AlaLys: 1.509 ± 0.718
6.792AlaLeu: 6.792 ± 1.566
3.774AlaMet: 3.774 ± 2.025
0.755AlaAsn: 0.755 ± 0.752
4.528AlaPro: 4.528 ± 2.705
3.774AlaGln: 3.774 ± 0.853
12.075AlaArg: 12.075 ± 4.615
3.774AlaSer: 3.774 ± 0.853
3.774AlaThr: 3.774 ± 0.859
9.057AlaVal: 9.057 ± 0.502
1.509AlaTrp: 1.509 ± 1.221
3.019AlaTyr: 3.019 ± 0.952
0.0AlaXaa: 0.0 ± 0.0
Cys
1.509CysAla: 1.509 ± 0.553
0.0CysCys: 0.0 ± 0.0
0.755CysAsp: 0.755 ± 0.611
0.755CysGlu: 0.755 ± 0.577
0.755CysPhe: 0.755 ± 0.611
3.019CysGly: 3.019 ± 1.436
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.755CysLeu: 0.755 ± 0.611
0.755CysMet: 0.755 ± 0.611
0.0CysAsn: 0.0 ± 0.0
0.755CysPro: 0.755 ± 0.611
1.509CysGln: 1.509 ± 1.154
1.509CysArg: 1.509 ± 1.221
0.755CysSer: 0.755 ± 0.611
1.509CysThr: 1.509 ± 0.718
1.509CysVal: 1.509 ± 0.553
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.019AspAla: 3.019 ± 1.436
0.0AspCys: 0.0 ± 0.0
1.509AspAsp: 1.509 ± 1.221
3.019AspGlu: 3.019 ± 1.605
2.264AspPhe: 2.264 ± 0.2
3.019AspGly: 3.019 ± 1.401
2.264AspHis: 2.264 ± 1.077
2.264AspIle: 2.264 ± 0.2
2.264AspLys: 2.264 ± 0.2
3.019AspLeu: 3.019 ± 0.557
0.755AspMet: 0.755 ± 1.08
0.0AspAsn: 0.0 ± 0.0
1.509AspPro: 1.509 ± 0.553
2.264AspGln: 2.264 ± 1.012
2.264AspArg: 2.264 ± 0.951
3.019AspSer: 3.019 ± 0.506
2.264AspThr: 2.264 ± 1.012
3.019AspVal: 3.019 ± 1.436
3.019AspTrp: 3.019 ± 0.952
0.755AspTyr: 0.755 ± 0.577
0.0AspXaa: 0.0 ± 0.0
Glu
8.302GluAla: 8.302 ± 3.023
0.755GluCys: 0.755 ± 0.577
5.283GluAsp: 5.283 ± 3.156
4.528GluGlu: 4.528 ± 2.024
0.755GluPhe: 0.755 ± 0.577
3.774GluGly: 3.774 ± 1.444
1.509GluHis: 1.509 ± 0.718
3.774GluIle: 3.774 ± 2.177
4.528GluLys: 4.528 ± 1.639
7.547GluLeu: 7.547 ± 1.341
0.755GluMet: 0.755 ± 0.577
0.0GluAsn: 0.0 ± 0.0
5.283GluPro: 5.283 ± 0.907
0.755GluGln: 0.755 ± 0.577
6.792GluArg: 6.792 ± 1.459
2.264GluSer: 2.264 ± 0.2
3.774GluThr: 3.774 ± 1.444
3.019GluVal: 3.019 ± 1.577
4.528GluTrp: 4.528 ± 1.534
1.509GluTyr: 1.509 ± 0.553
0.0GluXaa: 0.0 ± 0.0
Phe
3.019PheAla: 3.019 ± 1.106
0.0PheCys: 0.0 ± 0.0
0.755PheAsp: 0.755 ± 0.611
3.774PheGlu: 3.774 ± 0.853
0.0PhePhe: 0.0 ± 0.0
1.509PheGly: 1.509 ± 0.718
0.0PheHis: 0.0 ± 0.0
2.264PheIle: 2.264 ± 0.2
1.509PheLys: 1.509 ± 0.718
1.509PheLeu: 1.509 ± 0.7
2.264PheMet: 2.264 ± 1.138
0.755PheAsn: 0.755 ± 0.752
2.264PhePro: 2.264 ± 1.064
1.509PheGln: 1.509 ± 0.553
2.264PheArg: 2.264 ± 1.731
1.509PheSer: 1.509 ± 0.553
1.509PheThr: 1.509 ± 0.7
3.019PheVal: 3.019 ± 0.506
1.509PheTrp: 1.509 ± 0.553
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.528GlyAla: 4.528 ± 2.641
3.019GlyCys: 3.019 ± 1.473
3.774GlyAsp: 3.774 ± 0.354
4.528GlyGlu: 4.528 ± 0.779
7.547GlyPhe: 7.547 ± 2.509
9.811GlyGly: 9.811 ± 2.635
0.0GlyHis: 0.0 ± 0.0
4.528GlyIle: 4.528 ± 0.4
3.019GlyLys: 3.019 ± 0.506
2.264GlyLeu: 2.264 ± 1.077
2.264GlyMet: 2.264 ± 1.012
1.509GlyAsn: 1.509 ± 0.718
6.038GlyPro: 6.038 ± 1.011
2.264GlyGln: 2.264 ± 1.832
5.283GlyArg: 5.283 ± 0.508
3.019GlySer: 3.019 ± 1.436
5.283GlyThr: 5.283 ± 2.227
5.283GlyVal: 5.283 ± 0.907
4.528GlyTrp: 4.528 ± 2.765
3.774GlyTyr: 3.774 ± 2.885
0.0GlyXaa: 0.0 ± 0.0
His
0.755HisAla: 0.755 ± 0.611
0.0HisCys: 0.0 ± 0.0
1.509HisAsp: 1.509 ± 0.7
1.509HisGlu: 1.509 ± 1.154
0.755HisPhe: 0.755 ± 0.611
1.509HisGly: 1.509 ± 1.504
0.0HisHis: 0.0 ± 0.0
1.509HisIle: 1.509 ± 0.718
3.019HisLys: 3.019 ± 1.605
3.019HisLeu: 3.019 ± 0.506
1.509HisMet: 1.509 ± 1.221
0.0HisAsn: 0.0 ± 0.0
2.264HisPro: 2.264 ± 1.012
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
1.509HisThr: 1.509 ± 0.553
0.755HisVal: 0.755 ± 0.577
0.0HisTrp: 0.0 ± 0.0
0.755HisTyr: 0.755 ± 0.611
0.0HisXaa: 0.0 ± 0.0
Ile
3.019IleAla: 3.019 ± 2.03
0.0IleCys: 0.0 ± 0.0
3.019IleAsp: 3.019 ± 0.557
1.509IleGlu: 1.509 ± 0.718
1.509IlePhe: 1.509 ± 0.553
3.019IleGly: 3.019 ± 0.506
1.509IleHis: 1.509 ± 1.154
1.509IleIle: 1.509 ± 1.504
0.755IleLys: 0.755 ± 0.577
3.019IleLeu: 3.019 ± 1.106
0.755IleMet: 0.755 ± 0.577
2.264IleAsn: 2.264 ± 0.2
3.774IlePro: 3.774 ± 0.853
0.0IleGln: 0.0 ± 0.0
1.509IleArg: 1.509 ± 1.221
3.019IleSer: 3.019 ± 1.605
3.019IleThr: 3.019 ± 0.506
0.755IleVal: 0.755 ± 0.611
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.774LysAla: 3.774 ± 1.066
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
0.755LysGlu: 0.755 ± 0.611
0.755LysPhe: 0.755 ± 0.611
0.755LysGly: 0.755 ± 0.577
2.264LysHis: 2.264 ± 0.951
3.019LysIle: 3.019 ± 0.952
3.019LysLys: 3.019 ± 2.308
5.283LysLeu: 5.283 ± 1.97
0.755LysMet: 0.755 ± 0.577
0.0LysAsn: 0.0 ± 0.0
2.264LysPro: 2.264 ± 1.012
0.755LysGln: 0.755 ± 0.577
2.264LysArg: 2.264 ± 1.064
3.774LysSer: 3.774 ± 1.152
2.264LysThr: 2.264 ± 0.2
5.283LysVal: 5.283 ± 2.213
0.755LysTrp: 0.755 ± 0.577
1.509LysTyr: 1.509 ± 0.7
0.0LysXaa: 0.0 ± 0.0
Leu
9.057LeuAla: 9.057 ± 1.299
2.264LeuCys: 2.264 ± 1.012
6.792LeuAsp: 6.792 ± 1.229
5.283LeuGlu: 5.283 ± 0.572
6.038LeuPhe: 6.038 ± 0.16
6.038LeuGly: 6.038 ± 3.726
1.509LeuHis: 1.509 ± 1.221
4.528LeuIle: 4.528 ± 1.902
3.019LeuLys: 3.019 ± 1.577
3.774LeuLeu: 3.774 ± 2.167
4.528LeuMet: 4.528 ± 1.639
1.509LeuAsn: 1.509 ± 0.718
4.528LeuPro: 4.528 ± 2.641
5.283LeuGln: 5.283 ± 2.383
12.075LeuArg: 12.075 ± 1.381
1.509LeuSer: 1.509 ± 1.221
2.264LeuThr: 2.264 ± 1.064
7.547LeuVal: 7.547 ± 1.352
2.264LeuTrp: 2.264 ± 1.832
3.774LeuTyr: 3.774 ± 0.853
0.0LeuXaa: 0.0 ± 0.0
Met
2.264MetAla: 2.264 ± 1.064
1.509MetCys: 1.509 ± 0.553
0.0MetAsp: 0.0 ± 0.0
3.774MetGlu: 3.774 ± 1.444
0.755MetPhe: 0.755 ± 0.577
0.755MetGly: 0.755 ± 0.611
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.755MetLys: 0.755 ± 0.577
5.283MetLeu: 5.283 ± 2.039
0.755MetMet: 0.755 ± 0.752
1.509MetAsn: 1.509 ± 0.553
2.264MetPro: 2.264 ± 0.2
3.774MetGln: 3.774 ± 1.712
1.509MetArg: 1.509 ± 1.221
2.264MetSer: 2.264 ± 1.064
0.0MetThr: 0.0 ± 0.0
1.509MetVal: 1.509 ± 0.718
0.0MetTrp: 0.0 ± 0.0
0.755MetTyr: 0.755 ± 0.577
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
0.755AsnAsp: 0.755 ± 0.611
0.0AsnGlu: 0.0 ± 0.0
1.509AsnPhe: 1.509 ± 0.718
1.509AsnGly: 1.509 ± 1.154
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
0.755AsnLys: 0.755 ± 0.577
0.0AsnLeu: 0.0 ± 0.0
0.755AsnMet: 0.755 ± 0.611
0.755AsnAsn: 0.755 ± 0.752
1.509AsnPro: 1.509 ± 0.7
0.755AsnGln: 0.755 ± 0.577
1.509AsnArg: 1.509 ± 1.504
3.019AsnSer: 3.019 ± 0.557
1.509AsnThr: 1.509 ± 0.7
2.264AsnVal: 2.264 ± 1.319
0.755AsnTrp: 0.755 ± 0.752
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
7.547ProAla: 7.547 ± 2.424
1.509ProCys: 1.509 ± 0.718
4.528ProAsp: 4.528 ± 0.861
6.038ProGlu: 6.038 ± 2.382
0.755ProPhe: 0.755 ± 0.577
6.792ProGly: 6.792 ± 1.703
1.509ProHis: 1.509 ± 0.7
1.509ProIle: 1.509 ± 0.553
1.509ProLys: 1.509 ± 1.154
6.038ProLeu: 6.038 ± 2.057
0.755ProMet: 0.755 ± 0.501
0.755ProAsn: 0.755 ± 0.752
3.019ProPro: 3.019 ± 0.557
0.755ProGln: 0.755 ± 0.752
3.019ProArg: 3.019 ± 0.557
1.509ProSer: 1.509 ± 0.553
5.283ProThr: 5.283 ± 2.227
3.774ProVal: 3.774 ± 2.802
1.509ProTrp: 1.509 ± 1.221
3.774ProTyr: 3.774 ± 1.444
0.0ProXaa: 0.0 ± 0.0
Gln
0.755GlnAla: 0.755 ± 0.577
0.755GlnCys: 0.755 ± 0.611
1.509GlnAsp: 1.509 ± 0.718
5.283GlnGlu: 5.283 ± 3.362
1.509GlnPhe: 1.509 ± 0.7
3.019GlnGly: 3.019 ± 0.952
1.509GlnHis: 1.509 ± 0.718
0.755GlnIle: 0.755 ± 0.611
1.509GlnLys: 1.509 ± 1.221
3.019GlnLeu: 3.019 ± 1.436
0.755GlnMet: 0.755 ± 0.752
1.509GlnAsn: 1.509 ± 0.553
2.264GlnPro: 2.264 ± 1.353
3.774GlnGln: 3.774 ± 2.762
2.264GlnArg: 2.264 ± 0.951
0.0GlnSer: 0.0 ± 0.0
3.019GlnThr: 3.019 ± 0.557
3.019GlnVal: 3.019 ± 0.952
0.0GlnTrp: 0.0 ± 0.0
3.019GlnTyr: 3.019 ± 2.443
0.0GlnXaa: 0.0 ± 0.0
Arg
7.547ArgAla: 7.547 ± 0.652
0.0ArgCys: 0.0 ± 0.0
0.755ArgAsp: 0.755 ± 0.611
7.547ArgGlu: 7.547 ± 3.356
2.264ArgPhe: 2.264 ± 0.2
6.038ArgGly: 6.038 ± 2.052
0.755ArgHis: 0.755 ± 0.611
1.509ArgIle: 1.509 ± 1.154
3.774ArgLys: 3.774 ± 2.885
12.075ArgLeu: 12.075 ± 4.059
3.019ArgMet: 3.019 ± 1.577
1.509ArgAsn: 1.509 ± 0.7
2.264ArgPro: 2.264 ± 1.012
1.509ArgGln: 1.509 ± 0.553
15.849ArgArg: 15.849 ± 7.123
5.283ArgSer: 5.283 ± 1.548
0.755ArgThr: 0.755 ± 0.611
10.566ArgVal: 10.566 ± 2.017
3.019ArgTrp: 3.019 ± 0.506
3.774ArgTyr: 3.774 ± 0.354
0.0ArgXaa: 0.0 ± 0.0
Ser
3.774SerAla: 3.774 ± 0.354
0.755SerCys: 0.755 ± 0.611
2.264SerAsp: 2.264 ± 0.2
3.774SerGlu: 3.774 ± 0.354
0.755SerPhe: 0.755 ± 0.752
6.038SerGly: 6.038 ± 1.889
1.509SerHis: 1.509 ± 0.718
0.0SerIle: 0.0 ± 0.0
2.264SerLys: 2.264 ± 1.832
6.038SerLeu: 6.038 ± 1.022
0.755SerMet: 0.755 ± 0.752
0.755SerAsn: 0.755 ± 0.577
4.528SerPro: 4.528 ± 1.138
0.755SerGln: 0.755 ± 0.611
3.774SerArg: 3.774 ± 1.712
6.038SerSer: 6.038 ± 1.022
5.283SerThr: 5.283 ± 3.208
1.509SerVal: 1.509 ± 0.553
1.509SerTrp: 1.509 ± 0.7
1.509SerTyr: 1.509 ± 1.221
0.0SerXaa: 0.0 ± 0.0
Thr
5.283ThrAla: 5.283 ± 0.508
0.755ThrCys: 0.755 ± 0.752
1.509ThrAsp: 1.509 ± 1.504
1.509ThrGlu: 1.509 ± 0.553
0.755ThrPhe: 0.755 ± 0.577
6.792ThrGly: 6.792 ± 1.566
2.264ThrHis: 2.264 ± 1.077
1.509ThrIle: 1.509 ± 1.221
0.755ThrLys: 0.755 ± 0.577
8.302ThrLeu: 8.302 ± 2.333
0.755ThrMet: 0.755 ± 0.752
0.755ThrAsn: 0.755 ± 0.611
4.528ThrPro: 4.528 ± 1.509
3.774ThrGln: 3.774 ± 0.853
3.019ThrArg: 3.019 ± 0.952
3.019ThrSer: 3.019 ± 0.952
1.509ThrThr: 1.509 ± 1.504
3.774ThrVal: 3.774 ± 0.859
0.755ThrTrp: 0.755 ± 0.752
0.755ThrTyr: 0.755 ± 0.577
0.0ThrXaa: 0.0 ± 0.0
Val
6.792ValAla: 6.792 ± 1.459
0.755ValCys: 0.755 ± 0.577
2.264ValAsp: 2.264 ± 1.319
6.038ValGlu: 6.038 ± 2.057
1.509ValPhe: 1.509 ± 0.7
4.528ValGly: 4.528 ± 1.534
2.264ValHis: 2.264 ± 1.832
3.019ValIle: 3.019 ± 0.952
3.019ValLys: 3.019 ± 0.557
8.302ValLeu: 8.302 ± 4.518
0.0ValMet: 0.0 ± 0.0
2.264ValAsn: 2.264 ± 1.077
3.774ValPro: 3.774 ± 0.354
3.019ValGln: 3.019 ± 0.952
6.792ValArg: 6.792 ± 2.287
3.774ValSer: 3.774 ± 1.973
5.283ValThr: 5.283 ± 2.258
6.038ValVal: 6.038 ± 1.021
2.264ValTrp: 2.264 ± 0.951
4.528ValTyr: 4.528 ± 1.112
0.0ValXaa: 0.0 ± 0.0
Trp
3.019TrpAla: 3.019 ± 0.506
0.0TrpCys: 0.0 ± 0.0
2.264TrpAsp: 2.264 ± 1.077
0.755TrpGlu: 0.755 ± 0.611
0.0TrpPhe: 0.0 ± 0.0
0.755TrpGly: 0.755 ± 0.611
0.0TrpHis: 0.0 ± 0.0
0.755TrpIle: 0.755 ± 0.611
0.755TrpLys: 0.755 ± 0.752
3.019TrpLeu: 3.019 ± 0.952
2.264TrpMet: 2.264 ± 0.951
0.755TrpAsn: 0.755 ± 0.752
3.019TrpPro: 3.019 ± 0.557
0.755TrpGln: 0.755 ± 0.752
3.019TrpArg: 3.019 ± 1.577
2.264TrpSer: 2.264 ± 1.077
1.509TrpThr: 1.509 ± 0.553
2.264TrpVal: 2.264 ± 0.2
2.264TrpTrp: 2.264 ± 1.319
0.755TrpTyr: 0.755 ± 0.611
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.774TyrAla: 3.774 ± 1.152
2.264TyrCys: 2.264 ± 1.832
2.264TyrAsp: 2.264 ± 0.2
0.755TyrGlu: 0.755 ± 0.577
0.755TyrPhe: 0.755 ± 0.611
3.019TyrGly: 3.019 ± 1.106
0.755TyrHis: 0.755 ± 0.577
0.0TyrIle: 0.0 ± 0.0
1.509TyrLys: 1.509 ± 1.154
4.528TyrLeu: 4.528 ± 1.639
0.755TyrMet: 0.755 ± 0.577
0.0TyrAsn: 0.0 ± 0.0
1.509TyrPro: 1.509 ± 0.718
2.264TyrGln: 2.264 ± 0.2
3.019TyrArg: 3.019 ± 1.605
3.774TyrSer: 3.774 ± 1.066
0.755TyrThr: 0.755 ± 0.611
2.264TyrVal: 2.264 ± 0.2
0.0TyrTrp: 0.0 ± 0.0
0.755TyrTyr: 0.755 ± 0.577
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1326 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski