Amino acid dipepetide frequency for Hubei polero-like virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.792AlaAla: 3.792 ± 1.75
0.542AlaCys: 0.542 ± 0.379
0.542AlaAsp: 0.542 ± 0.551
2.709AlaGlu: 2.709 ± 1.244
1.625AlaPhe: 1.625 ± 1.156
4.334AlaGly: 4.334 ± 1.56
0.0AlaHis: 0.0 ± 0.0
3.792AlaIle: 3.792 ± 1.167
3.792AlaLys: 3.792 ± 2.65
5.959AlaLeu: 5.959 ± 1.506
1.625AlaMet: 1.625 ± 0.571
4.334AlaAsn: 4.334 ± 1.207
4.875AlaPro: 4.875 ± 3.225
3.792AlaGln: 3.792 ± 1.42
3.25AlaArg: 3.25 ± 1.724
3.25AlaSer: 3.25 ± 1.05
3.25AlaThr: 3.25 ± 1.349
2.167AlaVal: 2.167 ± 0.963
0.0AlaTrp: 0.0 ± 0.0
4.334AlaTyr: 4.334 ± 1.938
0.0AlaXaa: 0.0 ± 0.0
Cys
1.083CysAla: 1.083 ± 0.757
0.0CysCys: 0.0 ± 0.0
0.542CysAsp: 0.542 ± 0.551
1.625CysGlu: 1.625 ± 0.813
0.542CysPhe: 0.542 ± 0.379
1.083CysGly: 1.083 ± 1.102
0.0CysHis: 0.0 ± 0.0
1.083CysIle: 1.083 ± 0.609
1.083CysLys: 1.083 ± 0.545
0.542CysLeu: 0.542 ± 0.551
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.625CysPro: 1.625 ± 0.813
0.542CysGln: 0.542 ± 0.607
1.083CysArg: 1.083 ± 0.609
3.25CysSer: 3.25 ± 1.315
0.0CysThr: 0.0 ± 0.0
2.167CysVal: 2.167 ± 0.684
0.0CysTrp: 0.0 ± 0.0
0.542CysTyr: 0.542 ± 0.607
0.0CysXaa: 0.0 ± 0.0
Asp
2.709AspAla: 2.709 ± 2.116
1.083AspCys: 1.083 ± 0.474
2.709AspAsp: 2.709 ± 0.369
4.875AspGlu: 4.875 ± 1.714
1.083AspPhe: 1.083 ± 0.757
2.167AspGly: 2.167 ± 0.519
1.083AspHis: 1.083 ± 0.609
2.709AspIle: 2.709 ± 1.449
1.625AspLys: 1.625 ± 0.649
3.25AspLeu: 3.25 ± 1.142
0.542AspMet: 0.542 ± 0.379
1.625AspAsn: 1.625 ± 0.81
4.334AspPro: 4.334 ± 2.268
3.25AspGln: 3.25 ± 1.129
2.709AspArg: 2.709 ± 1.052
3.792AspSer: 3.792 ± 1.015
1.083AspThr: 1.083 ± 0.653
2.167AspVal: 2.167 ± 1.743
1.083AspTrp: 1.083 ± 0.778
2.167AspTyr: 2.167 ± 0.519
0.0AspXaa: 0.0 ± 0.0
Glu
1.625GluAla: 1.625 ± 0.571
2.167GluCys: 2.167 ± 0.684
3.25GluAsp: 3.25 ± 0.719
3.25GluGlu: 3.25 ± 1.209
3.25GluPhe: 3.25 ± 1.007
3.792GluGly: 3.792 ± 1.319
1.625GluHis: 1.625 ± 0.633
2.167GluIle: 2.167 ± 0.578
5.417GluLys: 5.417 ± 1.35
5.417GluLeu: 5.417 ± 3.175
0.542GluMet: 0.542 ± 0.551
1.083GluAsn: 1.083 ± 0.653
3.25GluPro: 3.25 ± 1.706
2.167GluGln: 2.167 ± 1.181
1.083GluArg: 1.083 ± 1.391
6.501GluSer: 6.501 ± 1.687
5.959GluThr: 5.959 ± 1.312
4.875GluVal: 4.875 ± 1.677
1.625GluTrp: 1.625 ± 0.987
2.709GluTyr: 2.709 ± 0.752
0.0GluXaa: 0.0 ± 0.0
Phe
1.625PheAla: 1.625 ± 0.81
0.542PheCys: 0.542 ± 0.551
3.25PheAsp: 3.25 ± 1.175
0.542PheGlu: 0.542 ± 0.551
2.709PhePhe: 2.709 ± 1.052
2.709PheGly: 2.709 ± 1.244
0.0PheHis: 0.0 ± 0.0
3.25PheIle: 3.25 ± 1.267
2.709PheLys: 2.709 ± 0.939
3.792PheLeu: 3.792 ± 1.98
0.0PheMet: 0.0 ± 0.0
2.709PheAsn: 2.709 ± 1.034
1.083PhePro: 1.083 ± 0.609
2.167PheGln: 2.167 ± 0.963
1.083PheArg: 1.083 ± 0.653
3.25PheSer: 3.25 ± 1.309
3.25PheThr: 3.25 ± 1.345
2.167PheVal: 2.167 ± 1.366
0.542PheTrp: 0.542 ± 0.379
1.083PheTyr: 1.083 ± 0.757
0.0PheXaa: 0.0 ± 0.0
Gly
5.417GlyAla: 5.417 ± 1.065
1.083GlyCys: 1.083 ± 0.474
3.25GlyAsp: 3.25 ± 1.209
2.167GlyGlu: 2.167 ± 1.082
3.792GlyPhe: 3.792 ± 1.1
4.334GlyGly: 4.334 ± 3.127
1.625GlyHis: 1.625 ± 1.217
2.167GlyIle: 2.167 ± 1.019
4.334GlyLys: 4.334 ± 0.644
4.875GlyLeu: 4.875 ± 1.425
1.083GlyMet: 1.083 ± 0.787
5.959GlyAsn: 5.959 ± 1.352
2.709GlyPro: 2.709 ± 1.052
1.625GlyGln: 1.625 ± 1.33
2.709GlyArg: 2.709 ± 1.878
5.417GlySer: 5.417 ± 1.268
3.792GlyThr: 3.792 ± 1.574
3.792GlyVal: 3.792 ± 0.824
1.083GlyTrp: 1.083 ± 0.474
3.792GlyTyr: 3.792 ± 0.534
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
2.167HisCys: 2.167 ± 0.963
1.083HisAsp: 1.083 ± 0.907
2.167HisGlu: 2.167 ± 0.708
0.542HisPhe: 0.542 ± 0.551
1.083HisGly: 1.083 ± 0.757
1.083HisHis: 1.083 ± 0.609
2.167HisIle: 2.167 ± 0.684
1.625HisLys: 1.625 ± 1.155
2.167HisLeu: 2.167 ± 0.684
0.542HisMet: 0.542 ± 0.379
1.625HisAsn: 1.625 ± 0.736
1.083HisPro: 1.083 ± 0.787
0.542HisGln: 0.542 ± 0.379
1.083HisArg: 1.083 ± 0.778
2.167HisSer: 2.167 ± 0.578
1.083HisThr: 1.083 ± 0.474
0.542HisVal: 0.542 ± 0.379
0.0HisTrp: 0.0 ± 0.0
1.083HisTyr: 1.083 ± 0.733
0.0HisXaa: 0.0 ± 0.0
Ile
2.709IleAla: 2.709 ± 1.196
2.709IleCys: 2.709 ± 1.386
4.334IleAsp: 4.334 ± 1.705
3.792IleGlu: 3.792 ± 1.1
3.25IlePhe: 3.25 ± 1.267
3.25IleGly: 3.25 ± 0.823
1.625IleHis: 1.625 ± 0.76
1.083IleIle: 1.083 ± 0.757
4.334IleLys: 4.334 ± 1.223
7.042IleLeu: 7.042 ± 2.608
1.625IleMet: 1.625 ± 0.571
3.792IleAsn: 3.792 ± 0.824
5.959IlePro: 5.959 ± 1.329
1.625IleGln: 1.625 ± 0.81
3.792IleArg: 3.792 ± 0.534
2.167IleSer: 2.167 ± 1.082
3.792IleThr: 3.792 ± 1.581
2.709IleVal: 2.709 ± 0.752
0.542IleTrp: 0.542 ± 0.607
0.542IleTyr: 0.542 ± 0.379
0.0IleXaa: 0.0 ± 0.0
Lys
3.25LysAla: 3.25 ± 1.248
1.083LysCys: 1.083 ± 0.609
1.625LysAsp: 1.625 ± 1.519
1.083LysGlu: 1.083 ± 0.757
1.625LysPhe: 1.625 ± 0.933
4.334LysGly: 4.334 ± 1.926
1.625LysHis: 1.625 ± 1.295
7.584LysIle: 7.584 ± 3.055
2.709LysLys: 2.709 ± 1.422
7.042LysLeu: 7.042 ± 1.734
3.25LysMet: 3.25 ± 1.487
1.625LysAsn: 1.625 ± 0.571
3.25LysPro: 3.25 ± 1.099
2.709LysGln: 2.709 ± 1.405
1.083LysArg: 1.083 ± 0.545
4.875LysSer: 4.875 ± 1.472
2.167LysThr: 2.167 ± 1.082
3.792LysVal: 3.792 ± 1.752
1.083LysTrp: 1.083 ± 0.474
2.167LysTyr: 2.167 ± 0.963
0.0LysXaa: 0.0 ± 0.0
Leu
7.042LeuAla: 7.042 ± 1.095
1.083LeuCys: 1.083 ± 0.474
3.792LeuAsp: 3.792 ± 1.333
7.584LeuGlu: 7.584 ± 1.728
3.25LeuPhe: 3.25 ± 0.823
6.501LeuGly: 6.501 ± 0.545
3.792LeuHis: 3.792 ± 1.892
5.959LeuIle: 5.959 ± 2.045
1.625LeuLys: 1.625 ± 1.029
8.667LeuLeu: 8.667 ± 2.564
1.083LeuMet: 1.083 ± 0.757
5.417LeuAsn: 5.417 ± 1.287
2.709LeuPro: 2.709 ± 1.114
2.709LeuGln: 2.709 ± 1.396
4.875LeuArg: 4.875 ± 1.937
9.751LeuSer: 9.751 ± 2.067
5.959LeuThr: 5.959 ± 2.033
4.334LeuVal: 4.334 ± 2.263
1.625LeuTrp: 1.625 ± 0.956
4.875LeuTyr: 4.875 ± 2.229
0.0LeuXaa: 0.0 ± 0.0
Met
0.542MetAla: 0.542 ± 0.551
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
3.792MetGlu: 3.792 ± 1.024
0.0MetPhe: 0.0 ± 0.0
0.542MetGly: 0.542 ± 0.551
0.0MetHis: 0.0 ± 0.0
0.542MetIle: 0.542 ± 0.379
0.542MetLys: 0.542 ± 0.379
2.709MetLeu: 2.709 ± 0.852
1.083MetMet: 1.083 ± 0.653
1.625MetAsn: 1.625 ± 0.736
0.542MetPro: 0.542 ± 0.695
1.083MetGln: 1.083 ± 0.653
1.083MetArg: 1.083 ± 0.787
1.625MetSer: 1.625 ± 0.956
2.167MetThr: 2.167 ± 0.578
1.083MetVal: 1.083 ± 0.545
0.0MetTrp: 0.0 ± 0.0
0.542MetTyr: 0.542 ± 0.551
0.0MetXaa: 0.0 ± 0.0
Asn
2.167AsnAla: 2.167 ± 0.708
0.0AsnCys: 0.0 ± 0.0
1.625AsnAsp: 1.625 ± 0.571
1.625AsnGlu: 1.625 ± 0.571
1.625AsnPhe: 1.625 ± 0.658
4.334AsnGly: 4.334 ± 2.017
1.625AsnHis: 1.625 ± 0.813
3.25AsnIle: 3.25 ± 1.539
2.709AsnLys: 2.709 ± 0.873
5.959AsnLeu: 5.959 ± 1.268
0.542AsnMet: 0.542 ± 0.379
2.709AsnAsn: 2.709 ± 1.312
2.167AsnPro: 2.167 ± 1.188
1.083AsnGln: 1.083 ± 0.757
5.959AsnArg: 5.959 ± 1.035
5.959AsnSer: 5.959 ± 0.692
2.167AsnThr: 2.167 ± 0.605
3.25AsnVal: 3.25 ± 0.349
0.542AsnTrp: 0.542 ± 0.551
2.167AsnTyr: 2.167 ± 1.314
0.0AsnXaa: 0.0 ± 0.0
Pro
1.625ProAla: 1.625 ± 0.81
0.0ProCys: 0.0 ± 0.0
2.167ProAsp: 2.167 ± 1.575
5.959ProGlu: 5.959 ± 2.127
2.709ProPhe: 2.709 ± 1.422
4.334ProGly: 4.334 ± 1.039
2.167ProHis: 2.167 ± 0.667
4.875ProIle: 4.875 ± 1.068
3.25ProLys: 3.25 ± 1.309
2.167ProLeu: 2.167 ± 1.074
0.542ProMet: 0.542 ± 0.379
1.625ProAsn: 1.625 ± 1.136
3.25ProPro: 3.25 ± 1.62
2.709ProGln: 2.709 ± 1.405
3.25ProArg: 3.25 ± 1.226
4.334ProSer: 4.334 ± 1.559
5.959ProThr: 5.959 ± 1.333
2.709ProVal: 2.709 ± 0.939
0.0ProTrp: 0.0 ± 0.0
1.083ProTyr: 1.083 ± 0.474
0.0ProXaa: 0.0 ± 0.0
Gln
3.25GlnAla: 3.25 ± 0.349
0.0GlnCys: 0.0 ± 0.0
1.625GlnAsp: 1.625 ± 1.136
1.625GlnGlu: 1.625 ± 1.217
1.083GlnPhe: 1.083 ± 0.907
3.25GlnGly: 3.25 ± 1.62
0.542GlnHis: 0.542 ± 0.379
3.25GlnIle: 3.25 ± 1.923
4.334GlnLys: 4.334 ± 1.622
3.25GlnLeu: 3.25 ± 1.498
2.167GlnMet: 2.167 ± 0.582
3.25GlnAsn: 3.25 ± 1.315
1.083GlnPro: 1.083 ± 0.757
2.709GlnGln: 2.709 ± 1.052
1.083GlnArg: 1.083 ± 0.778
2.167GlnSer: 2.167 ± 0.948
3.792GlnThr: 3.792 ± 1.024
0.542GlnVal: 0.542 ± 0.551
0.542GlnTrp: 0.542 ± 0.551
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.875ArgAla: 4.875 ± 1.781
0.542ArgCys: 0.542 ± 0.607
1.083ArgAsp: 1.083 ± 1.391
2.167ArgGlu: 2.167 ± 1.219
2.709ArgPhe: 2.709 ± 1.234
3.25ArgGly: 3.25 ± 1.469
1.083ArgHis: 1.083 ± 0.787
1.625ArgIle: 1.625 ± 1.155
2.709ArgLys: 2.709 ± 1.2
4.334ArgLeu: 4.334 ± 2.263
1.083ArgMet: 1.083 ± 0.653
4.334ArgAsn: 4.334 ± 2.111
3.792ArgPro: 3.792 ± 1.918
2.709ArgGln: 2.709 ± 0.369
3.792ArgArg: 3.792 ± 2.34
5.959ArgSer: 5.959 ± 2.217
3.25ArgThr: 3.25 ± 1.248
3.25ArgVal: 3.25 ± 1.142
0.0ArgTrp: 0.0 ± 0.0
2.709ArgTyr: 2.709 ± 1.034
0.0ArgXaa: 0.0 ± 0.0
Ser
4.334SerAla: 4.334 ± 1.969
1.083SerCys: 1.083 ± 0.609
8.126SerAsp: 8.126 ± 4.691
5.417SerGlu: 5.417 ± 2.054
2.167SerPhe: 2.167 ± 1.082
6.501SerGly: 6.501 ± 1.773
2.167SerHis: 2.167 ± 0.948
4.334SerIle: 4.334 ± 2.359
5.959SerLys: 5.959 ± 1.638
8.667SerLeu: 8.667 ± 1.17
0.0SerMet: 0.0 ± 0.0
4.334SerAsn: 4.334 ± 0.899
4.334SerPro: 4.334 ± 0.994
2.167SerGln: 2.167 ± 0.684
5.417SerArg: 5.417 ± 0.936
7.042SerSer: 7.042 ± 1.212
8.126SerThr: 8.126 ± 1.691
4.875SerVal: 4.875 ± 1.981
2.709SerTrp: 2.709 ± 1.082
2.167SerTyr: 2.167 ± 0.578
0.0SerXaa: 0.0 ± 0.0
Thr
5.959ThrAla: 5.959 ± 2.634
0.542ThrCys: 0.542 ± 0.379
2.709ThrAsp: 2.709 ± 1.082
4.334ThrGlu: 4.334 ± 1.771
3.792ThrPhe: 3.792 ± 1.436
4.875ThrGly: 4.875 ± 0.841
1.083ThrHis: 1.083 ± 0.474
4.334ThrIle: 4.334 ± 1.291
3.25ThrLys: 3.25 ± 0.988
5.417ThrLeu: 5.417 ± 0.47
1.083ThrMet: 1.083 ± 0.757
2.167ThrAsn: 2.167 ± 1.487
5.417ThrPro: 5.417 ± 2.129
2.709ThrGln: 2.709 ± 1.893
3.25ThrArg: 3.25 ± 1.596
5.417ThrSer: 5.417 ± 1.387
5.417ThrThr: 5.417 ± 1.803
2.709ThrVal: 2.709 ± 0.906
1.625ThrTrp: 1.625 ± 0.784
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.792ValAla: 3.792 ± 1.011
1.083ValCys: 1.083 ± 0.609
2.167ValAsp: 2.167 ± 0.708
3.792ValGlu: 3.792 ± 1.167
1.625ValPhe: 1.625 ± 1.174
1.083ValGly: 1.083 ± 0.788
1.625ValHis: 1.625 ± 0.658
3.25ValIle: 3.25 ± 1.828
2.709ValLys: 2.709 ± 1.405
7.042ValLeu: 7.042 ± 1.18
1.083ValMet: 1.083 ± 1.108
1.083ValAsn: 1.083 ± 0.83
2.709ValPro: 2.709 ± 0.852
2.709ValGln: 2.709 ± 1.629
3.792ValArg: 3.792 ± 1.365
8.126ValSer: 8.126 ± 1.508
2.167ValThr: 2.167 ± 0.684
3.25ValVal: 3.25 ± 0.608
0.542ValTrp: 0.542 ± 0.551
0.542ValTyr: 0.542 ± 0.379
0.0ValXaa: 0.0 ± 0.0
Trp
1.083TrpAla: 1.083 ± 1.102
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.083TrpGlu: 1.083 ± 0.474
0.0TrpPhe: 0.0 ± 0.0
1.625TrpGly: 1.625 ± 0.649
0.542TrpHis: 0.542 ± 0.551
1.083TrpIle: 1.083 ± 0.757
0.542TrpLys: 0.542 ± 0.607
1.625TrpLeu: 1.625 ± 1.155
0.542TrpMet: 0.542 ± 0.551
1.083TrpAsn: 1.083 ± 0.653
0.0TrpPro: 0.0 ± 0.0
0.542TrpGln: 0.542 ± 0.379
1.083TrpArg: 1.083 ± 0.733
1.625TrpSer: 1.625 ± 0.956
0.542TrpThr: 0.542 ± 0.379
1.625TrpVal: 1.625 ± 0.555
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.083TyrAla: 1.083 ± 0.474
1.083TyrCys: 1.083 ± 0.757
2.167TyrAsp: 2.167 ± 1.019
2.167TyrGlu: 2.167 ± 1.069
1.083TyrPhe: 1.083 ± 0.83
1.625TyrGly: 1.625 ± 0.649
0.542TyrHis: 0.542 ± 0.551
2.167TyrIle: 2.167 ± 1.229
2.709TyrLys: 2.709 ± 1.678
2.709TyrLeu: 2.709 ± 1.114
0.542TyrMet: 0.542 ± 0.695
1.083TyrAsn: 1.083 ± 0.778
0.542TyrPro: 0.542 ± 0.607
0.0TyrGln: 0.0 ± 0.0
3.792TyrArg: 3.792 ± 1.263
3.25TyrSer: 3.25 ± 0.608
2.167TyrThr: 2.167 ± 0.963
2.709TyrVal: 2.709 ± 0.792
1.083TyrTrp: 1.083 ± 0.545
1.083TyrTyr: 1.083 ± 0.609
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1847 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski