Schistosoma haematobium (Blood fluke)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda; Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma

Average proteome isoelectric point is 6.97

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 8963 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A6A5CSC2|A0A6A5CSC2_SCHHA Acyl-CoA thioesterase-related protein (Fragment) OS=Schistosoma haematobium OX=6185 GN=MS3_0012350 PE=3 SV=1
MM1 pKa = 7.58IIKK4 pKa = 10.52AIVLLCLTQYY14 pKa = 11.13LMCEE18 pKa = 4.2VAMMSTPASANIASDD33 pKa = 3.55EE34 pKa = 4.13VSEE37 pKa = 4.46VEE39 pKa = 6.17DD40 pKa = 3.67MVTDD44 pKa = 4.27DD45 pKa = 5.95GEE47 pKa = 4.34DD48 pKa = 3.52SKK50 pKa = 12.26SNDD53 pKa = 2.88SDD55 pKa = 3.97GNFVINLILTVIVHH69 pKa = 6.56LKK71 pKa = 10.02NLFGFGEE78 pKa = 4.42EE79 pKa = 4.58SSPSYY84 pKa = 9.18NTTMGVV90 pKa = 2.93

Molecular weight: 9.73 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A6A5DF27|A0A6A5DF27_SCHHA Putative flightless-I OS=Schistosoma haematobium OX=6185 GN=MS3_0015407 PE=4 SV=1
LL1 pKa = 7.18EE2 pKa = 5.12CFTEE6 pKa = 4.15ITILTHH12 pKa = 6.85HH13 pKa = 6.38YY14 pKa = 9.16RR15 pKa = 11.84SCSSGVALSARR26 pKa = 11.84AEE28 pKa = 3.81AALINWILINSRR40 pKa = 11.84LCAVRR45 pKa = 11.84LEE47 pKa = 4.31SSIKK51 pKa = 9.52ARR53 pKa = 11.84KK54 pKa = 8.77VRR56 pKa = 11.84DD57 pKa = 3.16RR58 pKa = 11.84VFGHH62 pKa = 7.05RR63 pKa = 11.84DD64 pKa = 3.29DD65 pKa = 4.33NSIVVTILKK74 pKa = 10.01HH75 pKa = 5.23RR76 pKa = 11.84LRR78 pKa = 11.84WLGHH82 pKa = 4.53VLRR85 pKa = 11.84MSSQRR90 pKa = 11.84IPRR93 pKa = 11.84RR94 pKa = 11.84ALFADD99 pKa = 4.67SGTGWKK105 pKa = 9.43KK106 pKa = 10.51RR107 pKa = 11.84RR108 pKa = 11.84GGQCMTWCRR117 pKa = 11.84GMKK120 pKa = 9.79EE121 pKa = 4.24SYY123 pKa = 10.06KK124 pKa = 10.77GLASVGPSRR133 pKa = 11.84RR134 pKa = 11.84PGWGSRR140 pKa = 11.84DD141 pKa = 3.55GATQWLEE148 pKa = 4.07TLSDD152 pKa = 3.54MAQNRR157 pKa = 11.84CQWRR161 pKa = 11.84SCCNLLLLSSQKK173 pKa = 10.39VAIEE177 pKa = 4.13TQCRR181 pKa = 11.84HH182 pKa = 6.54LIAA185 pKa = 5.91

Molecular weight: 21.04 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

8963

0

8963

5861687

19

9403

654.0

74.03

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.501 ± 0.022

2.188 ± 0.014

5.24 ± 0.017

5.406 ± 0.023

3.881 ± 0.014

4.405 ± 0.035

2.953 ± 0.012

6.654 ± 0.024

5.651 ± 0.022

9.807 ± 0.029

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.959 ± 0.008

7.088 ± 0.037

4.564 ± 0.025

4.26 ± 0.015

5.12 ± 0.022

10.205 ± 0.055

6.395 ± 0.022

5.385 ± 0.018

1.083 ± 0.007

3.256 ± 0.014
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski