Amino acid dipepetide frequency for Maize yellow mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.025AlaAla: 5.025 ± 0.931
0.67AlaCys: 0.67 ± 0.476
2.345AlaAsp: 2.345 ± 0.486
6.7AlaGlu: 6.7 ± 0.8
2.68AlaPhe: 2.68 ± 0.777
6.03AlaGly: 6.03 ± 1.513
1.34AlaHis: 1.34 ± 0.343
2.68AlaIle: 2.68 ± 0.412
2.345AlaLys: 2.345 ± 1.318
6.7AlaLeu: 6.7 ± 1.582
1.34AlaMet: 1.34 ± 0.461
2.01AlaAsn: 2.01 ± 1.049
5.36AlaPro: 5.36 ± 1.961
2.68AlaGln: 2.68 ± 0.588
5.025AlaArg: 5.025 ± 0.683
10.385AlaSer: 10.385 ± 1.99
5.025AlaThr: 5.025 ± 0.859
1.675AlaVal: 1.675 ± 0.424
0.335AlaTrp: 0.335 ± 0.277
3.35AlaTyr: 3.35 ± 0.73
0.0AlaXaa: 0.0 ± 0.0
Cys
1.34CysAla: 1.34 ± 0.962
0.67CysCys: 0.67 ± 0.29
0.67CysAsp: 0.67 ± 0.476
1.34CysGlu: 1.34 ± 0.296
0.335CysPhe: 0.335 ± 0.39
1.34CysGly: 1.34 ± 0.952
0.0CysHis: 0.0 ± 0.0
1.34CysIle: 1.34 ± 0.455
0.67CysLys: 0.67 ± 0.29
2.01CysLeu: 2.01 ± 0.892
0.335CysMet: 0.335 ± 0.238
0.0CysAsn: 0.0 ± 0.0
0.335CysPro: 0.335 ± 0.238
0.335CysGln: 0.335 ± 0.238
0.67CysArg: 0.67 ± 0.44
1.34CysSer: 1.34 ± 0.681
1.34CysThr: 1.34 ± 0.296
3.015CysVal: 3.015 ± 0.476
0.335CysTrp: 0.335 ± 0.238
0.67CysTyr: 0.67 ± 0.29
0.0CysXaa: 0.0 ± 0.0
Asp
4.355AspAla: 4.355 ± 1.07
1.005AspCys: 1.005 ± 0.446
3.015AspAsp: 3.015 ± 0.505
2.345AspGlu: 2.345 ± 0.822
2.68AspPhe: 2.68 ± 1.354
2.68AspGly: 2.68 ± 0.687
0.335AspHis: 0.335 ± 0.277
3.35AspIle: 3.35 ± 0.957
0.67AspLys: 0.67 ± 0.304
4.355AspLeu: 4.355 ± 0.446
0.335AspMet: 0.335 ± 0.238
0.335AspAsn: 0.335 ± 0.39
2.345AspPro: 2.345 ± 0.791
1.675AspGln: 1.675 ± 0.506
1.675AspArg: 1.675 ± 0.881
4.02AspSer: 4.02 ± 1.674
1.34AspThr: 1.34 ± 0.608
2.345AspVal: 2.345 ± 0.335
0.67AspTrp: 0.67 ± 0.371
1.34AspTyr: 1.34 ± 0.581
0.0AspXaa: 0.0 ± 0.0
Glu
4.69GluAla: 4.69 ± 0.536
1.675GluCys: 1.675 ± 0.962
4.02GluAsp: 4.02 ± 1.566
4.02GluGlu: 4.02 ± 1.117
3.015GluPhe: 3.015 ± 1.144
3.685GluGly: 3.685 ± 0.989
1.675GluHis: 1.675 ± 0.604
3.685GluIle: 3.685 ± 0.979
1.675GluLys: 1.675 ± 0.642
4.355GluLeu: 4.355 ± 0.75
0.67GluMet: 0.67 ± 0.29
0.67GluAsn: 0.67 ± 0.304
2.68GluPro: 2.68 ± 1.582
2.01GluGln: 2.01 ± 0.558
1.005GluArg: 1.005 ± 0.211
4.69GluSer: 4.69 ± 0.602
4.69GluThr: 4.69 ± 0.466
4.02GluVal: 4.02 ± 0.69
2.01GluTrp: 2.01 ± 0.778
1.34GluTyr: 1.34 ± 0.893
0.0GluXaa: 0.0 ± 0.0
Phe
2.01PheAla: 2.01 ± 0.393
1.005PheCys: 1.005 ± 0.723
2.01PheAsp: 2.01 ± 0.455
1.675PheGlu: 1.675 ± 0.877
1.675PhePhe: 1.675 ± 0.585
3.35PheGly: 3.35 ± 0.646
0.67PheHis: 0.67 ± 0.779
2.345PheIle: 2.345 ± 0.928
4.355PheLys: 4.355 ± 1.321
3.015PheLeu: 3.015 ± 0.708
1.34PheMet: 1.34 ± 0.738
1.34PheAsn: 1.34 ± 0.581
0.67PhePro: 0.67 ± 0.779
2.68PheGln: 2.68 ± 0.388
2.345PheArg: 2.345 ± 0.409
3.685PheSer: 3.685 ± 1.099
2.68PheThr: 2.68 ± 0.593
1.675PheVal: 1.675 ± 0.554
1.005PheTrp: 1.005 ± 0.404
1.005PheTyr: 1.005 ± 0.211
0.0PheXaa: 0.0 ± 0.0
Gly
1.34GlyAla: 1.34 ± 0.527
2.01GlyCys: 2.01 ± 0.646
1.675GlyAsp: 1.675 ± 0.72
1.675GlyGlu: 1.675 ± 0.301
5.025GlyPhe: 5.025 ± 1.25
10.05GlyGly: 10.05 ± 2.515
1.005GlyHis: 1.005 ± 0.404
1.005GlyIle: 1.005 ± 0.378
3.015GlyLys: 3.015 ± 0.79
4.02GlyLeu: 4.02 ± 1.484
0.335GlyMet: 0.335 ± 0.277
5.36GlyAsn: 5.36 ± 1.302
3.015GlyPro: 3.015 ± 0.77
1.005GlyGln: 1.005 ± 0.531
7.035GlyArg: 7.035 ± 2.253
9.38GlySer: 9.38 ± 0.859
4.02GlyThr: 4.02 ± 1.148
4.355GlyVal: 4.355 ± 0.836
2.345GlyTrp: 2.345 ± 0.746
4.02GlyTyr: 4.02 ± 0.803
0.0GlyXaa: 0.0 ± 0.0
His
1.34HisAla: 1.34 ± 0.738
0.335HisCys: 0.335 ± 0.238
0.67HisAsp: 0.67 ± 0.304
1.34HisGlu: 1.34 ± 0.41
0.67HisPhe: 0.67 ± 0.29
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.335HisIle: 0.335 ± 0.39
1.005HisLys: 1.005 ± 0.487
1.675HisLeu: 1.675 ± 1.082
0.0HisMet: 0.0 ± 0.0
2.01HisAsn: 2.01 ± 0.556
1.34HisPro: 1.34 ± 0.527
0.67HisGln: 0.67 ± 0.611
1.34HisArg: 1.34 ± 0.654
0.335HisSer: 0.335 ± 0.455
1.34HisThr: 1.34 ± 0.461
2.345HisVal: 2.345 ± 0.995
0.67HisTrp: 0.67 ± 0.29
1.005HisTyr: 1.005 ± 0.404
0.0HisXaa: 0.0 ± 0.0
Ile
3.015IleAla: 3.015 ± 0.642
0.67IleCys: 0.67 ± 0.29
2.01IleAsp: 2.01 ± 0.454
3.35IleGlu: 3.35 ± 0.547
0.67IlePhe: 0.67 ± 0.29
1.675IleGly: 1.675 ± 0.505
0.335IleHis: 0.335 ± 0.455
2.01IleIle: 2.01 ± 0.667
1.675IleLys: 1.675 ± 0.378
4.69IleLeu: 4.69 ± 1.47
0.335IleMet: 0.335 ± 0.238
1.34IleAsn: 1.34 ± 0.851
4.02IlePro: 4.02 ± 1.118
0.335IleGln: 0.335 ± 0.277
2.345IleArg: 2.345 ± 1.009
7.705IleSer: 7.705 ± 1.015
2.68IleThr: 2.68 ± 0.854
1.34IleVal: 1.34 ± 0.775
0.0IleTrp: 0.0 ± 0.0
1.34IleTyr: 1.34 ± 0.343
0.0IleXaa: 0.0 ± 0.0
Lys
3.015LysAla: 3.015 ± 0.493
0.335LysCys: 0.335 ± 0.238
2.68LysAsp: 2.68 ± 0.578
1.34LysGlu: 1.34 ± 0.681
2.68LysPhe: 2.68 ± 0.397
5.025LysGly: 5.025 ± 0.774
0.67LysHis: 0.67 ± 0.29
4.02LysIle: 4.02 ± 0.783
1.005LysLys: 1.005 ± 0.527
4.02LysLeu: 4.02 ± 0.835
1.675LysMet: 1.675 ± 0.532
1.005LysAsn: 1.005 ± 0.507
1.675LysPro: 1.675 ± 0.8
2.68LysGln: 2.68 ± 1.361
1.675LysArg: 1.675 ± 0.552
4.355LysSer: 4.355 ± 0.98
4.355LysThr: 4.355 ± 0.742
4.355LysVal: 4.355 ± 1.573
0.67LysTrp: 0.67 ± 0.476
0.335LysTyr: 0.335 ± 0.288
0.335LysXaa: 0.335 ± 0.277
Leu
8.375LeuAla: 8.375 ± 1.785
2.01LeuCys: 2.01 ± 0.892
2.68LeuAsp: 2.68 ± 0.693
7.035LeuGlu: 7.035 ± 0.717
5.025LeuPhe: 5.025 ± 1.878
4.69LeuGly: 4.69 ± 1.544
3.015LeuHis: 3.015 ± 1.435
2.01LeuIle: 2.01 ± 0.879
3.015LeuLys: 3.015 ± 0.514
11.725LeuLeu: 11.725 ± 3.481
1.675LeuMet: 1.675 ± 0.764
2.68LeuAsn: 2.68 ± 0.512
4.355LeuPro: 4.355 ± 1.19
5.025LeuGln: 5.025 ± 0.84
5.025LeuArg: 5.025 ± 1.279
9.38LeuSer: 9.38 ± 0.223
5.36LeuThr: 5.36 ± 0.783
6.7LeuVal: 6.7 ± 2.253
0.335LeuTrp: 0.335 ± 0.238
2.68LeuTyr: 2.68 ± 0.757
0.0LeuXaa: 0.0 ± 0.0
Met
1.675MetAla: 1.675 ± 0.552
0.0MetCys: 0.0 ± 0.0
0.335MetAsp: 0.335 ± 0.455
0.335MetGlu: 0.335 ± 0.238
0.335MetPhe: 0.335 ± 0.455
0.67MetGly: 0.67 ± 0.304
0.0MetHis: 0.0 ± 0.0
1.005MetIle: 1.005 ± 0.446
0.335MetLys: 0.335 ± 0.288
1.34MetLeu: 1.34 ± 0.455
0.67MetMet: 0.67 ± 0.29
1.34MetAsn: 1.34 ± 0.851
0.335MetPro: 0.335 ± 0.455
0.67MetGln: 0.67 ± 0.29
1.005MetArg: 1.005 ± 0.404
1.675MetSer: 1.675 ± 0.625
0.67MetThr: 0.67 ± 0.304
0.67MetVal: 0.67 ± 0.29
0.0MetTrp: 0.0 ± 0.0
1.34MetTyr: 1.34 ± 0.296
0.0MetXaa: 0.0 ± 0.0
Asn
4.355AsnAla: 4.355 ± 0.59
0.335AsnCys: 0.335 ± 0.238
1.675AsnAsp: 1.675 ± 0.447
0.67AsnGlu: 0.67 ± 0.555
1.34AsnPhe: 1.34 ± 0.443
4.355AsnGly: 4.355 ± 0.745
0.0AsnHis: 0.0 ± 0.0
0.335AsnIle: 0.335 ± 0.39
4.355AsnLys: 4.355 ± 0.937
2.68AsnLeu: 2.68 ± 0.4
0.335AsnMet: 0.335 ± 0.274
3.685AsnAsn: 3.685 ± 1.135
3.015AsnPro: 3.015 ± 1.124
1.675AsnGln: 1.675 ± 0.317
4.02AsnArg: 4.02 ± 1.054
3.35AsnSer: 3.35 ± 0.591
3.35AsnThr: 3.35 ± 0.634
0.67AsnVal: 0.67 ± 0.481
0.67AsnTrp: 0.67 ± 0.29
1.675AsnTyr: 1.675 ± 1.387
0.0AsnXaa: 0.0 ± 0.0
Pro
5.36ProAla: 5.36 ± 1.952
0.0ProCys: 0.0 ± 0.0
1.675ProAsp: 1.675 ± 0.437
3.015ProGlu: 3.015 ± 1.29
1.34ProPhe: 1.34 ± 0.581
4.02ProGly: 4.02 ± 1.114
1.675ProHis: 1.675 ± 0.317
1.675ProIle: 1.675 ± 0.378
3.685ProLys: 3.685 ± 0.845
2.01ProLeu: 2.01 ± 1.33
0.0ProMet: 0.0 ± 0.0
1.005ProAsn: 1.005 ± 0.489
6.365ProPro: 6.365 ± 2.458
4.02ProGln: 4.02 ± 0.802
4.355ProArg: 4.355 ± 1.076
6.03ProSer: 6.03 ± 2.347
6.365ProThr: 6.365 ± 1.129
3.685ProVal: 3.685 ± 0.702
0.335ProTrp: 0.335 ± 0.277
2.345ProTyr: 2.345 ± 0.974
0.0ProXaa: 0.0 ± 0.0
Gln
4.69GlnAla: 4.69 ± 1.973
1.675GlnCys: 1.675 ± 0.54
1.675GlnAsp: 1.675 ± 0.604
1.34GlnGlu: 1.34 ± 0.461
1.34GlnPhe: 1.34 ± 0.343
2.68GlnGly: 2.68 ± 0.907
1.675GlnHis: 1.675 ± 0.587
1.675GlnIle: 1.675 ± 0.867
3.685GlnLys: 3.685 ± 1.288
3.015GlnLeu: 3.015 ± 0.821
0.0GlnMet: 0.0 ± 0.0
4.02GlnAsn: 4.02 ± 0.872
1.675GlnPro: 1.675 ± 0.469
3.015GlnGln: 3.015 ± 0.888
3.35GlnArg: 3.35 ± 0.848
2.345GlnSer: 2.345 ± 1.197
2.68GlnThr: 2.68 ± 0.816
1.005GlnVal: 1.005 ± 0.733
0.335GlnTrp: 0.335 ± 0.455
0.335GlnTyr: 0.335 ± 0.277
0.0GlnXaa: 0.0 ± 0.0
Arg
5.36ArgAla: 5.36 ± 1.17
0.67ArgCys: 0.67 ± 0.779
2.345ArgAsp: 2.345 ± 1.706
4.02ArgGlu: 4.02 ± 0.534
2.01ArgPhe: 2.01 ± 1.065
4.355ArgGly: 4.355 ± 0.989
1.005ArgHis: 1.005 ± 0.723
2.68ArgIle: 2.68 ± 0.578
1.34ArgLys: 1.34 ± 0.343
9.715ArgLeu: 9.715 ± 1.689
1.34ArgMet: 1.34 ± 0.392
5.025ArgAsn: 5.025 ± 1.182
5.025ArgPro: 5.025 ± 1.966
1.005ArgGln: 1.005 ± 0.437
11.055ArgArg: 11.055 ± 4.573
3.015ArgSer: 3.015 ± 1.233
2.345ArgThr: 2.345 ± 0.391
3.685ArgVal: 3.685 ± 0.98
0.67ArgTrp: 0.67 ± 0.29
2.345ArgTyr: 2.345 ± 1.338
0.0ArgXaa: 0.0 ± 0.0
Ser
4.355SerAla: 4.355 ± 0.934
2.68SerCys: 2.68 ± 1.161
3.35SerAsp: 3.35 ± 0.591
4.355SerGlu: 4.355 ± 1.714
2.345SerPhe: 2.345 ± 0.719
6.03SerGly: 6.03 ± 1.137
1.34SerHis: 1.34 ± 0.661
6.03SerIle: 6.03 ± 0.724
5.025SerLys: 5.025 ± 0.805
13.4SerLeu: 13.4 ± 0.824
0.67SerMet: 0.67 ± 0.695
4.69SerAsn: 4.69 ± 0.841
5.695SerPro: 5.695 ± 1.571
4.355SerGln: 4.355 ± 1.78
6.7SerArg: 6.7 ± 2.03
10.72SerSer: 10.72 ± 1.867
4.02SerThr: 4.02 ± 0.612
7.37SerVal: 7.37 ± 0.973
2.01SerTrp: 2.01 ± 0.421
3.685SerTyr: 3.685 ± 0.692
0.0SerXaa: 0.0 ± 0.0
Thr
3.015ThrAla: 3.015 ± 0.853
2.01ThrCys: 2.01 ± 0.797
2.68ThrAsp: 2.68 ± 0.928
3.35ThrGlu: 3.35 ± 0.413
2.345ThrPhe: 2.345 ± 0.681
4.69ThrGly: 4.69 ± 1.442
0.67ThrHis: 0.67 ± 0.412
2.345ThrIle: 2.345 ± 0.9
2.68ThrLys: 2.68 ± 0.451
5.36ThrLeu: 5.36 ± 0.663
0.335ThrMet: 0.335 ± 0.455
2.345ThrAsn: 2.345 ± 0.486
7.035ThrPro: 7.035 ± 1.719
1.675ThrGln: 1.675 ± 0.714
5.025ThrArg: 5.025 ± 1.286
6.365ThrSer: 6.365 ± 1.815
3.685ThrThr: 3.685 ± 1.104
2.345ThrVal: 2.345 ± 0.771
1.005ThrTrp: 1.005 ± 0.446
2.01ThrTyr: 2.01 ± 0.421
0.0ThrXaa: 0.0 ± 0.0
Val
7.035ValAla: 7.035 ± 0.842
0.335ValCys: 0.335 ± 0.238
2.01ValAsp: 2.01 ± 0.558
3.685ValGlu: 3.685 ± 1.079
2.68ValPhe: 2.68 ± 0.635
4.02ValGly: 4.02 ± 0.528
1.34ValHis: 1.34 ± 0.581
1.005ValIle: 1.005 ± 0.211
2.68ValLys: 2.68 ± 0.593
6.03ValLeu: 6.03 ± 2.046
1.34ValMet: 1.34 ± 0.626
2.01ValAsn: 2.01 ± 0.556
2.345ValPro: 2.345 ± 0.822
4.69ValGln: 4.69 ± 0.456
3.015ValArg: 3.015 ± 0.539
5.695ValSer: 5.695 ± 1.516
2.68ValThr: 2.68 ± 0.81
6.7ValVal: 6.7 ± 1.668
1.34ValTrp: 1.34 ± 0.52
1.34ValTyr: 1.34 ± 0.443
0.0ValXaa: 0.0 ± 0.0
Trp
1.675TrpAla: 1.675 ± 0.437
0.0TrpCys: 0.0 ± 0.0
0.67TrpAsp: 0.67 ± 0.44
1.34TrpGlu: 1.34 ± 0.654
0.0TrpPhe: 0.0 ± 0.0
0.67TrpGly: 0.67 ± 0.304
0.335TrpHis: 0.335 ± 0.277
1.005TrpIle: 1.005 ± 0.446
0.67TrpLys: 0.67 ± 0.29
1.675TrpLeu: 1.675 ± 0.633
1.005TrpMet: 1.005 ± 0.446
0.67TrpAsn: 0.67 ± 0.29
1.005TrpPro: 1.005 ± 0.446
1.005TrpGln: 1.005 ± 0.211
1.34TrpArg: 1.34 ± 0.52
2.01TrpSer: 2.01 ± 0.361
0.0TrpThr: 0.0 ± 0.0
0.67TrpVal: 0.67 ± 0.29
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.675TyrAla: 1.675 ± 0.424
0.0TyrCys: 0.0 ± 0.0
2.68TyrAsp: 2.68 ± 0.957
3.35TyrGlu: 3.35 ± 0.547
2.345TyrPhe: 2.345 ± 0.665
1.675TyrGly: 1.675 ± 0.301
1.34TyrHis: 1.34 ± 0.52
1.005TyrIle: 1.005 ± 0.211
4.02TyrLys: 4.02 ± 0.954
1.005TyrLeu: 1.005 ± 0.404
0.335TyrMet: 0.335 ± 0.277
1.005TyrAsn: 1.005 ± 0.47
0.67TyrPro: 0.67 ± 0.29
1.005TyrGln: 1.005 ± 0.437
1.005TyrArg: 1.005 ± 0.372
2.68TyrSer: 2.68 ± 0.687
2.345TyrThr: 2.345 ± 0.652
3.015TyrVal: 3.015 ± 0.792
1.005TyrTrp: 1.005 ± 0.733
1.005TyrTyr: 1.005 ± 0.531
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.335XaaVal: 0.335 ± 0.277
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2986 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski