Amino acid dipepetide frequency for Lutzomyia reovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.329AlaAla: 3.329 ± 0.851
0.434AlaCys: 0.434 ± 0.251
2.46AlaAsp: 2.46 ± 0.444
1.737AlaGlu: 1.737 ± 0.466
2.026AlaPhe: 2.026 ± 0.38
2.171AlaGly: 2.171 ± 0.414
1.158AlaHis: 1.158 ± 0.301
6.946AlaIle: 6.946 ± 0.873
2.026AlaLys: 2.026 ± 0.648
6.512AlaLeu: 6.512 ± 1.11
0.579AlaMet: 0.579 ± 0.129
3.473AlaAsn: 3.473 ± 0.352
1.881AlaPro: 1.881 ± 0.622
2.894AlaGln: 2.894 ± 0.615
4.197AlaArg: 4.197 ± 0.911
3.907AlaSer: 3.907 ± 0.46
3.907AlaThr: 3.907 ± 0.433
3.329AlaVal: 3.329 ± 0.412
0.289AlaTrp: 0.289 ± 0.175
4.052AlaTyr: 4.052 ± 1.058
0.0AlaXaa: 0.0 ± 0.0
Cys
1.013CysAla: 1.013 ± 0.29
0.145CysCys: 0.145 ± 0.138
1.302CysAsp: 1.302 ± 0.494
0.0CysGlu: 0.0 ± 0.0
0.579CysPhe: 0.579 ± 0.353
0.434CysGly: 0.434 ± 0.229
0.724CysHis: 0.724 ± 0.333
0.434CysIle: 0.434 ± 0.19
0.289CysLys: 0.289 ± 0.208
0.579CysLeu: 0.579 ± 0.326
0.579CysMet: 0.579 ± 0.181
0.579CysAsn: 0.579 ± 0.229
0.289CysPro: 0.289 ± 0.151
0.724CysGln: 0.724 ± 0.27
0.724CysArg: 0.724 ± 0.281
0.724CysSer: 0.724 ± 0.305
1.158CysThr: 1.158 ± 0.545
0.289CysVal: 0.289 ± 0.151
0.289CysTrp: 0.289 ± 0.194
0.434CysTyr: 0.434 ± 0.208
0.0CysXaa: 0.0 ± 0.0
Asp
4.052AspAla: 4.052 ± 0.912
1.158AspCys: 1.158 ± 0.627
4.92AspAsp: 4.92 ± 0.536
2.315AspGlu: 2.315 ± 0.665
1.158AspPhe: 1.158 ± 0.306
2.315AspGly: 2.315 ± 0.639
0.868AspHis: 0.868 ± 0.338
5.499AspIle: 5.499 ± 0.911
1.737AspLys: 1.737 ± 0.262
4.052AspLeu: 4.052 ± 0.805
2.75AspMet: 2.75 ± 0.663
2.605AspAsn: 2.605 ± 0.613
3.618AspPro: 3.618 ± 0.473
3.763AspGln: 3.763 ± 0.355
2.75AspArg: 2.75 ± 0.579
3.329AspSer: 3.329 ± 0.796
4.052AspThr: 4.052 ± 0.787
2.75AspVal: 2.75 ± 0.685
0.289AspTrp: 0.289 ± 0.265
2.46AspTyr: 2.46 ± 0.506
0.0AspXaa: 0.0 ± 0.0
Glu
2.315GluAla: 2.315 ± 0.396
0.579GluCys: 0.579 ± 0.241
1.447GluAsp: 1.447 ± 0.183
1.158GluGlu: 1.158 ± 0.246
3.039GluPhe: 3.039 ± 0.685
1.013GluGly: 1.013 ± 0.31
1.447GluHis: 1.447 ± 0.344
3.907GluIle: 3.907 ± 0.398
1.592GluLys: 1.592 ± 0.514
4.92GluLeu: 4.92 ± 0.88
1.013GluMet: 1.013 ± 0.347
2.605GluAsn: 2.605 ± 0.54
1.881GluPro: 1.881 ± 0.366
2.026GluGln: 2.026 ± 0.442
2.171GluArg: 2.171 ± 0.741
2.171GluSer: 2.171 ± 0.568
2.605GluThr: 2.605 ± 0.583
2.605GluVal: 2.605 ± 0.381
0.434GluTrp: 0.434 ± 0.251
3.763GluTyr: 3.763 ± 0.522
0.0GluXaa: 0.0 ± 0.0
Phe
1.013PheAla: 1.013 ± 0.378
0.145PheCys: 0.145 ± 0.133
2.171PheAsp: 2.171 ± 0.571
1.737PheGlu: 1.737 ± 0.593
0.868PhePhe: 0.868 ± 0.277
2.026PheGly: 2.026 ± 0.57
1.013PheHis: 1.013 ± 0.362
3.618PheIle: 3.618 ± 0.705
2.75PheLys: 2.75 ± 0.647
2.171PheLeu: 2.171 ± 0.6
1.302PheMet: 1.302 ± 0.289
3.329PheAsn: 3.329 ± 0.73
1.737PhePro: 1.737 ± 0.563
1.592PheGln: 1.592 ± 0.365
1.881PheArg: 1.881 ± 0.384
4.197PheSer: 4.197 ± 0.74
3.618PheThr: 3.618 ± 0.714
1.737PheVal: 1.737 ± 0.421
0.289PheTrp: 0.289 ± 0.274
2.026PheTyr: 2.026 ± 0.488
0.0PheXaa: 0.0 ± 0.0
Gly
1.592GlyAla: 1.592 ± 0.488
0.145GlyCys: 0.145 ± 0.133
2.171GlyAsp: 2.171 ± 0.637
2.171GlyGlu: 2.171 ± 0.551
1.447GlyPhe: 1.447 ± 0.29
1.013GlyGly: 1.013 ± 0.328
0.579GlyHis: 0.579 ± 0.296
3.329GlyIle: 3.329 ± 0.707
2.171GlyLys: 2.171 ± 0.48
5.499GlyLeu: 5.499 ± 0.469
1.158GlyMet: 1.158 ± 0.232
1.013GlyAsn: 1.013 ± 0.353
0.868GlyPro: 0.868 ± 0.216
1.158GlyGln: 1.158 ± 0.345
2.75GlyArg: 2.75 ± 0.525
3.184GlySer: 3.184 ± 0.707
3.184GlyThr: 3.184 ± 0.442
1.737GlyVal: 1.737 ± 0.407
0.724GlyTrp: 0.724 ± 0.233
2.315GlyTyr: 2.315 ± 0.465
0.0GlyXaa: 0.0 ± 0.0
His
2.75HisAla: 2.75 ± 0.624
0.434HisCys: 0.434 ± 0.205
1.447HisAsp: 1.447 ± 0.254
1.737HisGlu: 1.737 ± 0.609
0.868HisPhe: 0.868 ± 0.438
0.868HisGly: 0.868 ± 0.296
1.302HisHis: 1.302 ± 0.442
4.052HisIle: 4.052 ± 0.888
1.158HisLys: 1.158 ± 0.455
3.618HisLeu: 3.618 ± 0.765
0.579HisMet: 0.579 ± 0.255
1.737HisAsn: 1.737 ± 0.754
1.013HisPro: 1.013 ± 0.504
1.737HisGln: 1.737 ± 0.478
2.171HisArg: 2.171 ± 0.471
1.447HisSer: 1.447 ± 0.426
3.329HisThr: 3.329 ± 0.659
1.592HisVal: 1.592 ± 0.505
0.145HisTrp: 0.145 ± 0.138
0.434HisTyr: 0.434 ± 0.159
0.0HisXaa: 0.0 ± 0.0
Ile
5.065IleAla: 5.065 ± 0.494
0.868IleCys: 0.868 ± 0.539
4.776IleAsp: 4.776 ± 0.737
3.473IleGlu: 3.473 ± 0.582
3.329IlePhe: 3.329 ± 0.722
5.065IleGly: 5.065 ± 1.019
1.881IleHis: 1.881 ± 0.525
6.657IleIle: 6.657 ± 0.884
2.894IleLys: 2.894 ± 0.619
5.21IleLeu: 5.21 ± 0.877
1.447IleMet: 1.447 ± 0.479
7.091IleAsn: 7.091 ± 1.292
5.21IlePro: 5.21 ± 1.456
6.078IleGln: 6.078 ± 0.456
5.21IleArg: 5.21 ± 0.764
6.368IleSer: 6.368 ± 0.781
10.854IleThr: 10.854 ± 1.737
4.052IleVal: 4.052 ± 0.679
0.434IleTrp: 0.434 ± 0.165
4.776IleTyr: 4.776 ± 0.604
0.0IleXaa: 0.0 ± 0.0
Lys
2.75LysAla: 2.75 ± 0.493
0.145LysCys: 0.145 ± 0.124
1.592LysAsp: 1.592 ± 0.605
0.868LysGlu: 0.868 ± 0.27
1.592LysPhe: 1.592 ± 0.632
1.592LysGly: 1.592 ± 0.493
1.158LysHis: 1.158 ± 0.349
2.605LysIle: 2.605 ± 0.813
1.447LysLys: 1.447 ± 0.4
4.197LysLeu: 4.197 ± 0.343
0.434LysMet: 0.434 ± 0.292
1.447LysAsn: 1.447 ± 0.438
1.592LysPro: 1.592 ± 0.418
2.605LysGln: 2.605 ± 0.492
1.447LysArg: 1.447 ± 0.429
3.039LysSer: 3.039 ± 0.664
3.473LysThr: 3.473 ± 0.826
1.158LysVal: 1.158 ± 0.283
0.289LysTrp: 0.289 ± 0.257
2.75LysTyr: 2.75 ± 0.755
0.0LysXaa: 0.0 ± 0.0
Leu
4.92LeuAla: 4.92 ± 0.897
1.013LeuCys: 1.013 ± 0.421
5.21LeuAsp: 5.21 ± 0.528
3.763LeuGlu: 3.763 ± 0.552
4.631LeuPhe: 4.631 ± 0.564
4.342LeuGly: 4.342 ± 0.663
4.342LeuHis: 4.342 ± 0.936
7.091LeuIle: 7.091 ± 0.822
3.184LeuLys: 3.184 ± 0.66
9.696LeuLeu: 9.696 ± 0.865
1.447LeuMet: 1.447 ± 0.386
5.499LeuAsn: 5.499 ± 0.708
5.933LeuPro: 5.933 ± 0.782
4.486LeuGln: 4.486 ± 0.66
5.499LeuArg: 5.499 ± 0.899
7.959LeuSer: 7.959 ± 1.313
7.236LeuThr: 7.236 ± 0.895
2.75LeuVal: 2.75 ± 0.63
0.724LeuTrp: 0.724 ± 0.275
3.618LeuTyr: 3.618 ± 0.487
0.0LeuXaa: 0.0 ± 0.0
Met
0.724MetAla: 0.724 ± 0.388
0.579MetCys: 0.579 ± 0.2
0.868MetAsp: 0.868 ± 0.238
1.158MetGlu: 1.158 ± 0.483
0.145MetPhe: 0.145 ± 0.124
0.724MetGly: 0.724 ± 0.251
0.434MetHis: 0.434 ± 0.199
2.315MetIle: 2.315 ± 0.494
0.579MetLys: 0.579 ± 0.21
2.605MetLeu: 2.605 ± 0.547
0.724MetMet: 0.724 ± 0.283
1.302MetAsn: 1.302 ± 0.345
1.302MetPro: 1.302 ± 0.206
1.302MetGln: 1.302 ± 0.4
1.302MetArg: 1.302 ± 0.552
1.302MetSer: 1.302 ± 0.577
2.315MetThr: 2.315 ± 0.388
1.447MetVal: 1.447 ± 0.361
0.0MetTrp: 0.0 ± 0.0
1.302MetTyr: 1.302 ± 0.496
0.0MetXaa: 0.0 ± 0.0
Asn
4.052AsnAla: 4.052 ± 0.818
0.868AsnCys: 0.868 ± 0.158
3.763AsnAsp: 3.763 ± 0.552
2.894AsnGlu: 2.894 ± 0.461
2.171AsnPhe: 2.171 ± 0.618
2.46AsnGly: 2.46 ± 0.532
2.75AsnHis: 2.75 ± 0.69
7.236AsnIle: 7.236 ± 1.429
1.881AsnLys: 1.881 ± 0.542
4.052AsnLeu: 4.052 ± 0.478
1.302AsnMet: 1.302 ± 0.302
2.75AsnAsn: 2.75 ± 0.519
1.881AsnPro: 1.881 ± 0.508
2.46AsnGln: 2.46 ± 0.417
2.605AsnArg: 2.605 ± 0.674
3.329AsnSer: 3.329 ± 0.368
3.618AsnThr: 3.618 ± 0.37
2.894AsnVal: 2.894 ± 0.375
0.724AsnTrp: 0.724 ± 0.272
3.184AsnTyr: 3.184 ± 0.431
0.0AsnXaa: 0.0 ± 0.0
Pro
3.184ProAla: 3.184 ± 0.542
0.434ProCys: 0.434 ± 0.217
2.171ProAsp: 2.171 ± 0.747
2.026ProGlu: 2.026 ± 0.453
1.881ProPhe: 1.881 ± 0.417
2.026ProGly: 2.026 ± 0.662
2.171ProHis: 2.171 ± 0.572
4.342ProIle: 4.342 ± 0.818
1.302ProLys: 1.302 ± 0.449
4.776ProLeu: 4.776 ± 0.711
1.302ProMet: 1.302 ± 0.452
3.039ProAsn: 3.039 ± 0.703
2.75ProPro: 2.75 ± 0.459
3.329ProGln: 3.329 ± 0.543
2.026ProArg: 2.026 ± 0.44
3.907ProSer: 3.907 ± 0.739
4.92ProThr: 4.92 ± 0.384
2.026ProVal: 2.026 ± 0.636
0.579ProTrp: 0.579 ± 0.208
4.776ProTyr: 4.776 ± 1.024
0.0ProXaa: 0.0 ± 0.0
Gln
3.473GlnAla: 3.473 ± 0.526
0.868GlnCys: 0.868 ± 0.244
2.171GlnAsp: 2.171 ± 0.493
2.75GlnGlu: 2.75 ± 0.452
2.605GlnPhe: 2.605 ± 0.245
1.158GlnGly: 1.158 ± 0.297
2.026GlnHis: 2.026 ± 0.291
4.776GlnIle: 4.776 ± 0.742
0.868GlnLys: 0.868 ± 0.409
6.078GlnLeu: 6.078 ± 0.89
0.868GlnMet: 0.868 ± 0.296
1.881GlnAsn: 1.881 ± 0.29
3.039GlnPro: 3.039 ± 0.455
3.329GlnGln: 3.329 ± 0.571
3.329GlnArg: 3.329 ± 0.831
3.618GlnSer: 3.618 ± 0.648
4.052GlnThr: 4.052 ± 0.698
3.039GlnVal: 3.039 ± 0.372
0.724GlnTrp: 0.724 ± 0.136
2.46GlnTyr: 2.46 ± 0.575
0.0GlnXaa: 0.0 ± 0.0
Arg
3.329ArgAla: 3.329 ± 0.65
0.579ArgCys: 0.579 ± 0.311
3.763ArgAsp: 3.763 ± 0.375
1.737ArgGlu: 1.737 ± 0.586
2.46ArgPhe: 2.46 ± 0.648
2.026ArgGly: 2.026 ± 0.363
1.302ArgHis: 1.302 ± 0.316
6.802ArgIle: 6.802 ± 0.254
1.737ArgLys: 1.737 ± 0.262
5.644ArgLeu: 5.644 ± 0.676
1.447ArgMet: 1.447 ± 0.338
3.039ArgAsn: 3.039 ± 0.729
1.737ArgPro: 1.737 ± 0.397
2.46ArgGln: 2.46 ± 0.693
2.75ArgArg: 2.75 ± 0.857
3.618ArgSer: 3.618 ± 0.692
3.763ArgThr: 3.763 ± 0.941
2.46ArgVal: 2.46 ± 0.495
0.724ArgTrp: 0.724 ± 0.317
3.618ArgTyr: 3.618 ± 0.543
0.0ArgXaa: 0.0 ± 0.0
Ser
3.039SerAla: 3.039 ± 0.789
0.724SerCys: 0.724 ± 0.344
5.065SerAsp: 5.065 ± 0.591
3.184SerGlu: 3.184 ± 0.944
2.026SerPhe: 2.026 ± 0.375
2.75SerGly: 2.75 ± 0.731
2.894SerHis: 2.894 ± 0.444
5.499SerIle: 5.499 ± 0.36
2.171SerLys: 2.171 ± 0.514
5.933SerLeu: 5.933 ± 0.544
1.447SerMet: 1.447 ± 0.549
3.184SerAsn: 3.184 ± 0.45
6.368SerPro: 6.368 ± 1.003
3.907SerGln: 3.907 ± 0.504
3.473SerArg: 3.473 ± 0.334
5.499SerSer: 5.499 ± 0.838
5.789SerThr: 5.789 ± 0.612
4.052SerVal: 4.052 ± 0.697
1.158SerTrp: 1.158 ± 0.265
2.46SerTyr: 2.46 ± 0.536
0.0SerXaa: 0.0 ± 0.0
Thr
4.197ThrAla: 4.197 ± 0.517
0.868ThrCys: 0.868 ± 0.248
4.776ThrAsp: 4.776 ± 0.804
3.763ThrGlu: 3.763 ± 0.839
4.631ThrPhe: 4.631 ± 0.728
1.737ThrGly: 1.737 ± 0.5
2.605ThrHis: 2.605 ± 0.435
7.236ThrIle: 7.236 ± 0.619
3.184ThrLys: 3.184 ± 0.547
7.815ThrLeu: 7.815 ± 0.964
1.592ThrMet: 1.592 ± 0.296
5.789ThrAsn: 5.789 ± 0.814
4.776ThrPro: 4.776 ± 0.827
4.92ThrGln: 4.92 ± 1.033
4.486ThrArg: 4.486 ± 0.624
6.946ThrSer: 6.946 ± 0.803
8.538ThrThr: 8.538 ± 1.14
2.315ThrVal: 2.315 ± 0.258
0.434ThrTrp: 0.434 ± 0.261
4.342ThrTyr: 4.342 ± 1.09
0.0ThrXaa: 0.0 ± 0.0
Val
2.315ValAla: 2.315 ± 0.296
0.434ValCys: 0.434 ± 0.314
2.75ValAsp: 2.75 ± 1.111
2.026ValGlu: 2.026 ± 0.329
1.737ValPhe: 1.737 ± 0.421
1.302ValGly: 1.302 ± 0.255
1.447ValHis: 1.447 ± 0.267
3.039ValIle: 3.039 ± 0.474
1.737ValLys: 1.737 ± 0.241
4.197ValLeu: 4.197 ± 0.62
1.013ValMet: 1.013 ± 0.342
3.329ValAsn: 3.329 ± 0.725
2.894ValPro: 2.894 ± 0.886
1.881ValGln: 1.881 ± 0.565
3.039ValArg: 3.039 ± 0.73
2.894ValSer: 2.894 ± 0.413
2.894ValThr: 2.894 ± 0.671
1.592ValVal: 1.592 ± 0.687
0.434ValTrp: 0.434 ± 0.247
2.315ValTyr: 2.315 ± 0.404
0.0ValXaa: 0.0 ± 0.0
Trp
0.579TrpAla: 0.579 ± 0.319
0.145TrpCys: 0.145 ± 0.133
0.289TrpAsp: 0.289 ± 0.164
0.289TrpGlu: 0.289 ± 0.19
0.434TrpPhe: 0.434 ± 0.255
0.145TrpGly: 0.145 ± 0.137
0.145TrpHis: 0.145 ± 0.138
0.579TrpIle: 0.579 ± 0.23
0.434TrpLys: 0.434 ± 0.262
0.868TrpLeu: 0.868 ± 0.259
0.434TrpMet: 0.434 ± 0.292
0.868TrpAsn: 0.868 ± 0.522
0.868TrpPro: 0.868 ± 0.266
0.434TrpGln: 0.434 ± 0.269
0.868TrpArg: 0.868 ± 0.334
0.434TrpSer: 0.434 ± 0.147
0.724TrpThr: 0.724 ± 0.481
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.145TrpTyr: 0.145 ± 0.128
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.618TyrAla: 3.618 ± 0.297
0.724TyrCys: 0.724 ± 0.345
3.329TyrAsp: 3.329 ± 0.589
3.907TyrGlu: 3.907 ± 0.679
1.592TyrPhe: 1.592 ± 0.39
3.039TyrGly: 3.039 ± 0.424
2.171TyrHis: 2.171 ± 0.356
4.776TyrIle: 4.776 ± 0.84
3.039TyrLys: 3.039 ± 0.619
4.92TyrLeu: 4.92 ± 0.662
0.868TyrMet: 0.868 ± 0.579
2.315TyrAsn: 2.315 ± 0.278
3.329TyrPro: 3.329 ± 0.895
2.026TyrGln: 2.026 ± 0.369
2.315TyrArg: 2.315 ± 0.883
2.75TyrSer: 2.75 ± 0.891
4.92TyrThr: 4.92 ± 0.65
1.592TyrVal: 1.592 ± 0.28
0.0TyrTrp: 0.0 ± 0.0
3.039TyrTyr: 3.039 ± 0.645
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (6911 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski