Amino acid dipepetide frequency for Dissoconium aciculare CBS 342.82

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.538AlaAla: 10.538 ± 0.068	1.158AlaCys: 1.158 ± 0.018	4.769AlaAsp: 4.769 ± 0.037	5.457AlaGlu: 5.457 ± 0.046	3.232AlaPhe: 3.232 ± 0.032	6.276AlaGly: 6.276 ± 0.04	2.033AlaHis: 2.033 ± 0.025	4.389AlaIle: 4.389 ± 0.033	4.201AlaLys: 4.201 ± 0.033	8.197AlaLeu: 8.197 ± 0.046	1.994AlaMet: 1.994 ± 0.018	3.19AlaAsn: 3.19 ± 0.032	5.042AlaPro: 5.042 ± 0.045	3.84AlaGln: 3.84 ± 0.038	5.726AlaArg: 5.726 ± 0.04	7.872AlaSer: 7.872 ± 0.046	5.759AlaThr: 5.759 ± 0.04	5.642AlaVal: 5.642 ± 0.042	1.204AlaTrp: 1.204 ± 0.017	2.211AlaTyr: 2.211 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	1.057CysAla: 1.057 ± 0.016	0.309CysCys: 0.309 ± 0.01	0.7CysAsp: 0.7 ± 0.014	0.622CysGlu: 0.622 ± 0.012	0.555CysPhe: 0.555 ± 0.011	0.961CysGly: 0.961 ± 0.017	0.364CysHis: 0.364 ± 0.01	0.718CysIle: 0.718 ± 0.013	0.503CysLys: 0.503 ± 0.011	1.281CysLeu: 1.281 ± 0.018	0.289CysMet: 0.289 ± 0.008	0.447CysAsn: 0.447 ± 0.011	0.676CysPro: 0.676 ± 0.014	0.465CysGln: 0.465 ± 0.011	0.892CysArg: 0.892 ± 0.018	1.017CysSer: 1.017 ± 0.017	0.738CysThr: 0.738 ± 0.015	0.8CysVal: 0.8 ± 0.015	0.186CysTrp: 0.186 ± 0.007	0.346CysTyr: 0.346 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.319AspAla: 5.319 ± 0.036	0.632AspCys: 0.632 ± 0.012	4.823AspAsp: 4.823 ± 0.058	4.555AspGlu: 4.555 ± 0.042	2.233AspPhe: 2.233 ± 0.025	4.17AspGly: 4.17 ± 0.036	1.428AspHis: 1.428 ± 0.019	2.816AspIle: 2.816 ± 0.029	2.193AspLys: 2.193 ± 0.023	5.164AspLeu: 5.164 ± 0.038	1.189AspMet: 1.189 ± 0.016	1.815AspAsn: 1.815 ± 0.02	3.152AspPro: 3.152 ± 0.025	1.935AspGln: 1.935 ± 0.023	3.301AspArg: 3.301 ± 0.035	4.003AspSer: 4.003 ± 0.034	2.767AspThr: 2.767 ± 0.023	3.824AspVal: 3.824 ± 0.03	0.855AspTrp: 0.855 ± 0.015	1.514AspTyr: 1.514 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	5.3GluAla: 5.3 ± 0.042	0.613GluCys: 0.613 ± 0.012	4.173GluAsp: 4.173 ± 0.041	4.811GluGlu: 4.811 ± 0.057	1.85GluPhe: 1.85 ± 0.021	3.505GluGly: 3.505 ± 0.03	1.492GluHis: 1.492 ± 0.02	2.982GluIle: 2.982 ± 0.024	3.376GluLys: 3.376 ± 0.035	4.968GluLeu: 4.968 ± 0.043	1.407GluMet: 1.407 ± 0.015	2.145GluAsn: 2.145 ± 0.024	2.497GluPro: 2.497 ± 0.027	2.627GluGln: 2.627 ± 0.03	4.156GluArg: 4.156 ± 0.04	4.124GluSer: 4.124 ± 0.036	3.295GluThr: 3.295 ± 0.023	3.432GluVal: 3.432 ± 0.032	0.803GluTrp: 0.803 ± 0.015	1.531GluTyr: 1.531 ± 0.022	0.0GluXaa: 0.0 ± 0.0
Phe	3.314PheAla: 3.314 ± 0.028	0.556PheCys: 0.556 ± 0.011	2.262PheAsp: 2.262 ± 0.022	2.127PheGlu: 2.127 ± 0.025	1.493PhePhe: 1.493 ± 0.021	2.73PheGly: 2.73 ± 0.03	0.902PheHis: 0.902 ± 0.015	1.649PheIle: 1.649 ± 0.022	1.345PheLys: 1.345 ± 0.021	3.355PheLeu: 3.355 ± 0.03	0.715PheMet: 0.715 ± 0.014	1.289PheAsn: 1.289 ± 0.017	1.865PhePro: 1.865 ± 0.021	1.342PheGln: 1.342 ± 0.016	2.021PheArg: 2.021 ± 0.024	2.831PheSer: 2.831 ± 0.029	2.109PheThr: 2.109 ± 0.022	2.351PheVal: 2.351 ± 0.026	0.602PheTrp: 0.602 ± 0.013	0.992PheTyr: 0.992 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	5.489GlyAla: 5.489 ± 0.041	0.87GlyCys: 0.87 ± 0.016	3.598GlyAsp: 3.598 ± 0.028	3.566GlyGlu: 3.566 ± 0.032	2.616GlyPhe: 2.616 ± 0.027	5.909GlyGly: 5.909 ± 0.066	1.709GlyHis: 1.709 ± 0.019	3.28GlyIle: 3.28 ± 0.028	3.306GlyLys: 3.306 ± 0.033	5.806GlyLeu: 5.806 ± 0.041	1.543GlyMet: 1.543 ± 0.021	2.482GlyAsn: 2.482 ± 0.026	3.192GlyPro: 3.192 ± 0.029	2.58GlyGln: 2.58 ± 0.028	4.334GlyArg: 4.334 ± 0.035	5.576GlySer: 5.576 ± 0.041	3.861GlyThr: 3.861 ± 0.033	4.154GlyVal: 4.154 ± 0.034	1.087GlyTrp: 1.087 ± 0.021	1.917GlyTyr: 1.917 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	2.197HisAla: 2.197 ± 0.026	0.364HisCys: 0.364 ± 0.01	1.534HisAsp: 1.534 ± 0.021	1.434HisGlu: 1.434 ± 0.02	0.933HisPhe: 0.933 ± 0.015	1.766HisGly: 1.766 ± 0.022	1.062HisHis: 1.062 ± 0.022	1.247HisIle: 1.247 ± 0.018	0.934HisLys: 0.934 ± 0.013	2.348HisLeu: 2.348 ± 0.026	0.5HisMet: 0.5 ± 0.01	0.906HisAsn: 0.906 ± 0.015	1.61HisPro: 1.61 ± 0.021	1.041HisGln: 1.041 ± 0.017	1.754HisArg: 1.754 ± 0.021	1.973HisSer: 1.973 ± 0.023	1.376HisThr: 1.376 ± 0.019	1.569HisVal: 1.569 ± 0.019	0.332HisTrp: 0.332 ± 0.009	0.673HisTyr: 0.673 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.569IleAla: 4.569 ± 0.035	0.768IleCys: 0.768 ± 0.015	2.953IleAsp: 2.953 ± 0.03	2.815IleGlu: 2.815 ± 0.028	1.921IlePhe: 1.921 ± 0.023	3.149IleGly: 3.149 ± 0.033	1.17IleHis: 1.17 ± 0.014	2.459IleIle: 2.459 ± 0.025	2.002IleLys: 2.002 ± 0.023	4.385IleLeu: 4.385 ± 0.035	0.982IleMet: 0.982 ± 0.014	1.711IleAsn: 1.711 ± 0.021	2.837IlePro: 2.837 ± 0.024	1.756IleGln: 1.756 ± 0.017	2.877IleArg: 2.877 ± 0.029	3.824IleSer: 3.824 ± 0.028	2.853IleThr: 2.853 ± 0.026	3.246IleVal: 3.246 ± 0.027	0.662IleTrp: 0.662 ± 0.013	1.332IleTyr: 1.332 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.202LysAla: 4.202 ± 0.034	0.483LysCys: 0.483 ± 0.012	2.628LysAsp: 2.628 ± 0.028	2.901LysGlu: 2.901 ± 0.033	1.394LysPhe: 1.394 ± 0.02	2.657LysGly: 2.657 ± 0.027	1.124LysHis: 1.124 ± 0.017	2.237LysIle: 2.237 ± 0.023	2.935LysLys: 2.935 ± 0.041	3.868LysLeu: 3.868 ± 0.032	0.942LysMet: 0.942 ± 0.015	1.601LysAsn: 1.601 ± 0.019	2.555LysPro: 2.555 ± 0.031	1.931LysGln: 1.931 ± 0.024	3.397LysArg: 3.397 ± 0.029	3.529LysSer: 3.529 ± 0.032	2.721LysThr: 2.721 ± 0.025	2.603LysVal: 2.603 ± 0.027	0.618LysTrp: 0.618 ± 0.012	1.255LysTyr: 1.255 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	8.287LeuAla: 8.287 ± 0.05	1.245LeuCys: 1.245 ± 0.02	5.091LeuAsp: 5.091 ± 0.033	5.289LeuGlu: 5.289 ± 0.043	3.184LeuPhe: 3.184 ± 0.032	5.638LeuGly: 5.638 ± 0.039	2.404LeuHis: 2.404 ± 0.025	3.841LeuIle: 3.841 ± 0.033	3.93LeuLys: 3.93 ± 0.034	8.391LeuLeu: 8.391 ± 0.056	1.683LeuMet: 1.683 ± 0.021	3.019LeuAsn: 3.019 ± 0.026	5.593LeuPro: 5.593 ± 0.041	4.071LeuGln: 4.071 ± 0.037	6.098LeuArg: 6.098 ± 0.042	7.227LeuSer: 7.227 ± 0.046	4.818LeuThr: 4.818 ± 0.04	5.214LeuVal: 5.214 ± 0.038	1.149LeuTrp: 1.149 ± 0.017	2.232LeuTyr: 2.232 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	2.131MetAla: 2.131 ± 0.024	0.277MetCys: 0.277 ± 0.009	1.127MetAsp: 1.127 ± 0.018	1.115MetGlu: 1.115 ± 0.017	0.723MetPhe: 0.723 ± 0.013	1.253MetGly: 1.253 ± 0.016	0.532MetHis: 0.532 ± 0.011	0.993MetIle: 0.993 ± 0.015	0.924MetLys: 0.924 ± 0.016	1.88MetLeu: 1.88 ± 0.022	0.568MetMet: 0.568 ± 0.016	0.772MetAsn: 0.772 ± 0.014	1.267MetPro: 1.267 ± 0.018	0.922MetGln: 0.922 ± 0.016	1.363MetArg: 1.363 ± 0.019	1.871MetSer: 1.871 ± 0.022	1.316MetThr: 1.316 ± 0.02	1.176MetVal: 1.176 ± 0.018	0.256MetTrp: 0.256 ± 0.008	0.5MetTyr: 0.5 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.488AsnAla: 3.488 ± 0.032	0.417AsnCys: 0.417 ± 0.011	2.1AsnAsp: 2.1 ± 0.024	1.914AsnGlu: 1.914 ± 0.022	1.357AsnPhe: 1.357 ± 0.018	2.862AsnGly: 2.862 ± 0.024	0.896AsnHis: 0.896 ± 0.013	1.983AsnIle: 1.983 ± 0.024	1.469AsnLys: 1.469 ± 0.02	3.15AsnLeu: 3.15 ± 0.032	0.751AsnMet: 0.751 ± 0.013	1.562AsnAsn: 1.562 ± 0.025	2.269AsnPro: 2.269 ± 0.022	1.255AsnGln: 1.255 ± 0.018	1.959AsnArg: 1.959 ± 0.02	2.743AsnSer: 2.743 ± 0.027	2.134AsnThr: 2.134 ± 0.024	2.342AsnVal: 2.342 ± 0.025	0.474AsnTrp: 0.474 ± 0.011	0.974AsnTyr: 0.974 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.624ProAla: 5.624 ± 0.043	0.567ProCys: 0.567 ± 0.012	2.963ProAsp: 2.963 ± 0.024	3.358ProGlu: 3.358 ± 0.028	1.956ProPhe: 1.956 ± 0.022	3.714ProGly: 3.714 ± 0.033	1.404ProHis: 1.404 ± 0.021	2.527ProIle: 2.527 ± 0.026	2.407ProLys: 2.407 ± 0.027	4.595ProLeu: 4.595 ± 0.036	1.057ProMet: 1.057 ± 0.017	2.109ProAsn: 2.109 ± 0.024	4.941ProPro: 4.941 ± 0.074	2.429ProGln: 2.429 ± 0.027	3.595ProArg: 3.595 ± 0.036	5.913ProSer: 5.913 ± 0.045	4.084ProThr: 4.084 ± 0.037	3.37ProVal: 3.37 ± 0.032	0.692ProTrp: 0.692 ± 0.013	1.388ProTyr: 1.388 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.8GlnAla: 3.8 ± 0.035	0.495GlnCys: 0.495 ± 0.01	2.123GlnAsp: 2.123 ± 0.021	2.29GlnGlu: 2.29 ± 0.025	1.235GlnPhe: 1.235 ± 0.018	2.381GlnGly: 2.381 ± 0.03	1.266GlnHis: 1.266 ± 0.02	1.999GlnIle: 1.999 ± 0.019	1.936GlnLys: 1.936 ± 0.024	3.477GlnLeu: 3.477 ± 0.029	0.871GlnMet: 0.871 ± 0.015	1.584GlnAsn: 1.584 ± 0.018	2.506GlnPro: 2.506 ± 0.03	2.988GlnGln: 2.988 ± 0.073	2.993GlnArg: 2.993 ± 0.028	3.374GlnSer: 3.374 ± 0.029	2.454GlnThr: 2.454 ± 0.026	2.146GlnVal: 2.146 ± 0.025	0.59GlnTrp: 0.59 ± 0.012	1.184GlnTyr: 1.184 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.449ArgAla: 5.449 ± 0.038	0.87ArgCys: 0.87 ± 0.016	3.639ArgAsp: 3.639 ± 0.031	3.995ArgGlu: 3.995 ± 0.037	2.158ArgPhe: 2.158 ± 0.022	3.848ArgGly: 3.848 ± 0.037	1.749ArgHis: 1.749 ± 0.021	3.028ArgIle: 3.028 ± 0.025	3.544ArgLys: 3.544 ± 0.032	5.755ArgLeu: 5.755 ± 0.04	1.42ArgMet: 1.42 ± 0.02	2.372ArgAsn: 2.372 ± 0.025	3.818ArgPro: 3.818 ± 0.035	2.878ArgGln: 2.878 ± 0.032	5.663ArgArg: 5.663 ± 0.05	5.347ArgSer: 5.347 ± 0.045	3.659ArgThr: 3.659 ± 0.034	3.458ArgVal: 3.458 ± 0.03	0.983ArgTrp: 0.983 ± 0.015	1.634ArgTyr: 1.634 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	7.425SerAla: 7.425 ± 0.049	0.973SerCys: 0.973 ± 0.017	4.34SerAsp: 4.34 ± 0.033	4.044SerGlu: 4.044 ± 0.036	2.9SerPhe: 2.9 ± 0.026	5.499SerGly: 5.499 ± 0.04	2.081SerHis: 2.081 ± 0.025	4.028SerIle: 4.028 ± 0.03	3.622SerLys: 3.622 ± 0.035	7.205SerLeu: 7.205 ± 0.044	1.703SerMet: 1.703 ± 0.02	3.14SerAsn: 3.14 ± 0.031	5.392SerPro: 5.392 ± 0.055	3.341SerGln: 3.341 ± 0.033	5.405SerArg: 5.405 ± 0.046	9.269SerSer: 9.269 ± 0.093	5.823SerThr: 5.823 ± 0.051	4.512SerVal: 4.512 ± 0.032	1.099SerTrp: 1.099 ± 0.016	1.973SerTyr: 1.973 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	5.778ThrAla: 5.778 ± 0.034	0.823ThrCys: 0.823 ± 0.015	2.797ThrAsp: 2.797 ± 0.025	2.885ThrGlu: 2.885 ± 0.026	2.269ThrPhe: 2.269 ± 0.023	3.985ThrGly: 3.985 ± 0.032	1.382ThrHis: 1.382 ± 0.019	3.171ThrIle: 3.171 ± 0.033	2.521ThrLys: 2.521 ± 0.03	5.254ThrLeu: 5.254 ± 0.039	1.184ThrMet: 1.184 ± 0.015	2.211ThrAsn: 2.211 ± 0.025	4.095ThrPro: 4.095 ± 0.033	2.149ThrGln: 2.149 ± 0.025	3.406ThrArg: 3.406 ± 0.03	5.809ThrSer: 5.809 ± 0.047	4.899ThrThr: 4.899 ± 0.06	3.569ThrVal: 3.569 ± 0.036	0.831ThrTrp: 0.831 ± 0.015	1.555ThrTyr: 1.555 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.517ValAla: 5.517 ± 0.035	0.875ValCys: 0.875 ± 0.016	3.604ValAsp: 3.604 ± 0.028	3.72ValGlu: 3.72 ± 0.031	2.246ValPhe: 2.246 ± 0.027	3.833ValGly: 3.833 ± 0.035	1.461ValHis: 1.461 ± 0.018	2.847ValIle: 2.847 ± 0.026	2.763ValLys: 2.763 ± 0.028	5.53ValLeu: 5.53 ± 0.042	1.249ValMet: 1.249 ± 0.019	2.124ValAsn: 2.124 ± 0.021	3.444ValPro: 3.444 ± 0.026	2.466ValGln: 2.466 ± 0.026	3.723ValArg: 3.723 ± 0.027	4.458ValSer: 4.458 ± 0.035	3.421ValThr: 3.421 ± 0.034	4.256ValVal: 4.256 ± 0.04	0.822ValTrp: 0.822 ± 0.014	1.593ValTyr: 1.593 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.072TrpAla: 1.072 ± 0.016	0.203TrpCys: 0.203 ± 0.007	0.814TrpAsp: 0.814 ± 0.015	0.746TrpGlu: 0.746 ± 0.014	0.51TrpPhe: 0.51 ± 0.011	0.76TrpGly: 0.76 ± 0.014	0.37TrpHis: 0.37 ± 0.009	0.756TrpIle: 0.756 ± 0.013	0.69TrpLys: 0.69 ± 0.013	1.341TrpLeu: 1.341 ± 0.021	0.361TrpMet: 0.361 ± 0.008	0.569TrpAsn: 0.569 ± 0.01	0.611TrpPro: 0.611 ± 0.012	0.632TrpGln: 0.632 ± 0.012	1.009TrpArg: 1.009 ± 0.018	1.085TrpSer: 1.085 ± 0.016	0.942TrpThr: 0.942 ± 0.015	0.762TrpVal: 0.762 ± 0.014	0.255TrpTrp: 0.255 ± 0.009	0.404TrpTyr: 0.404 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.178TyrAla: 2.178 ± 0.022	0.423TyrCys: 0.423 ± 0.009	1.651TyrAsp: 1.651 ± 0.02	1.441TyrGlu: 1.441 ± 0.019	1.085TyrPhe: 1.085 ± 0.017	1.981TyrGly: 1.981 ± 0.028	0.725TyrHis: 0.725 ± 0.012	1.32TyrIle: 1.32 ± 0.018	0.982TyrLys: 0.982 ± 0.015	2.455TyrLeu: 2.455 ± 0.022	0.56TyrMet: 0.56 ± 0.011	1.051TyrAsn: 1.051 ± 0.017	1.331TyrPro: 1.331 ± 0.02	1.043TyrGln: 1.043 ± 0.018	1.594TyrArg: 1.594 ± 0.02	1.927TyrSer: 1.927 ± 0.023	1.545TyrThr: 1.545 ± 0.022	1.527TyrVal: 1.527 ± 0.018	0.391TyrTrp: 0.391 ± 0.009	0.889TyrTyr: 0.889 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.021XaaXaa: 0.021 ± 0.019

Statistics based on 10290 proteins (4500263 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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