Amino acid dipepetide frequency for Tessaracoccus rhinocerotis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.168AlaAla: 17.168 ± 0.196	0.857AlaCys: 0.857 ± 0.029	7.779AlaAsp: 7.779 ± 0.095	8.211AlaGlu: 8.211 ± 0.094	3.505AlaPhe: 3.505 ± 0.067	11.15AlaGly: 11.15 ± 0.121	2.429AlaHis: 2.429 ± 0.053	4.772AlaIle: 4.772 ± 0.083	2.667AlaLys: 2.667 ± 0.061	12.41AlaLeu: 12.41 ± 0.131	2.825AlaMet: 2.825 ± 0.046	2.493AlaAsn: 2.493 ± 0.051	5.561AlaPro: 5.561 ± 0.095	3.555AlaGln: 3.555 ± 0.057	8.388AlaArg: 8.388 ± 0.127	6.132AlaSer: 6.132 ± 0.082	7.353AlaThr: 7.353 ± 0.1	10.704AlaVal: 10.704 ± 0.125	1.868AlaTrp: 1.868 ± 0.043	2.134AlaTyr: 2.134 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.754CysAla: 0.754 ± 0.026	0.073CysCys: 0.073 ± 0.009	0.438CysAsp: 0.438 ± 0.024	0.394CysGlu: 0.394 ± 0.02	0.209CysPhe: 0.209 ± 0.016	0.721CysGly: 0.721 ± 0.031	0.18CysHis: 0.18 ± 0.014	0.242CysIle: 0.242 ± 0.015	0.079CysLys: 0.079 ± 0.007	0.599CysLeu: 0.599 ± 0.022	0.116CysMet: 0.116 ± 0.011	0.144CysAsn: 0.144 ± 0.012	0.388CysPro: 0.388 ± 0.022	0.161CysGln: 0.161 ± 0.012	0.529CysArg: 0.529 ± 0.025	0.399CysSer: 0.399 ± 0.018	0.419CysThr: 0.419 ± 0.021	0.534CysVal: 0.534 ± 0.023	0.101CysTrp: 0.101 ± 0.01	0.126CysTyr: 0.126 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.304AspAla: 7.304 ± 0.092	0.34AspCys: 0.34 ± 0.021	4.049AspAsp: 4.049 ± 0.082	4.617AspGlu: 4.617 ± 0.066	1.889AspPhe: 1.889 ± 0.046	6.55AspGly: 6.55 ± 0.102	1.366AspHis: 1.366 ± 0.039	2.089AspIle: 2.089 ± 0.052	1.217AspLys: 1.217 ± 0.036	6.312AspLeu: 6.312 ± 0.084	0.916AspMet: 0.916 ± 0.03	1.218AspAsn: 1.218 ± 0.035	4.231AspPro: 4.231 ± 0.071	1.674AspGln: 1.674 ± 0.038	3.847AspArg: 3.847 ± 0.071	2.818AspSer: 2.818 ± 0.053	2.677AspThr: 2.677 ± 0.049	5.997AspVal: 5.997 ± 0.087	1.128AspTrp: 1.128 ± 0.038	1.274AspTyr: 1.274 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	7.615GluAla: 7.615 ± 0.11	0.415GluCys: 0.415 ± 0.021	3.3GluAsp: 3.3 ± 0.06	3.772GluGlu: 3.772 ± 0.073	2.013GluPhe: 2.013 ± 0.044	4.6GluGly: 4.6 ± 0.064	1.612GluHis: 1.612 ± 0.04	2.719GluIle: 2.719 ± 0.054	1.298GluLys: 1.298 ± 0.047	7.482GluLeu: 7.482 ± 0.094	1.139GluMet: 1.139 ± 0.032	1.25GluAsn: 1.25 ± 0.033	3.589GluPro: 3.589 ± 0.065	2.537GluGln: 2.537 ± 0.05	4.951GluArg: 4.951 ± 0.082	2.902GluSer: 2.902 ± 0.052	3.118GluThr: 3.118 ± 0.051	5.657GluVal: 5.657 ± 0.087	0.93GluTrp: 0.93 ± 0.032	1.173GluTyr: 1.173 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.65PheAla: 3.65 ± 0.063	0.26PheCys: 0.26 ± 0.017	2.313PheAsp: 2.313 ± 0.05	1.956PheGlu: 1.956 ± 0.047	1.011PhePhe: 1.011 ± 0.037	3.236PheGly: 3.236 ± 0.062	0.712PheHis: 0.712 ± 0.026	1.275PheIle: 1.275 ± 0.036	0.595PheLys: 0.595 ± 0.025	2.922PheLeu: 2.922 ± 0.067	0.583PheMet: 0.583 ± 0.023	0.945PheAsn: 0.945 ± 0.032	1.444PhePro: 1.444 ± 0.038	0.85PheGln: 0.85 ± 0.027	1.937PheArg: 1.937 ± 0.042	1.827PheSer: 1.827 ± 0.041	2.126PheThr: 2.126 ± 0.05	2.814PheVal: 2.814 ± 0.056	0.535PheTrp: 0.535 ± 0.022	0.662PheTyr: 0.662 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	9.557GlyAla: 9.557 ± 0.126	0.69GlyCys: 0.69 ± 0.03	5.163GlyAsp: 5.163 ± 0.098	5.515GlyGlu: 5.515 ± 0.076	3.269GlyPhe: 3.269 ± 0.055	7.59GlyGly: 7.59 ± 0.118	2.12GlyHis: 2.12 ± 0.044	4.416GlyIle: 4.416 ± 0.082	2.137GlyLys: 2.137 ± 0.046	9.106GlyLeu: 9.106 ± 0.122	2.139GlyMet: 2.139 ± 0.041	2.169GlyAsn: 2.169 ± 0.047	4.093GlyPro: 4.093 ± 0.062	2.81GlyGln: 2.81 ± 0.055	6.786GlyArg: 6.786 ± 0.086	5.402GlySer: 5.402 ± 0.083	5.596GlyThr: 5.596 ± 0.079	7.902GlyVal: 7.902 ± 0.105	1.926GlyTrp: 1.926 ± 0.049	2.177GlyTyr: 2.177 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.307HisAla: 2.307 ± 0.046	0.165HisCys: 0.165 ± 0.013	1.408HisAsp: 1.408 ± 0.037	1.329HisGlu: 1.329 ± 0.039	0.633HisPhe: 0.633 ± 0.025	2.068HisGly: 2.068 ± 0.04	0.666HisHis: 0.666 ± 0.031	0.702HisIle: 0.702 ± 0.028	0.373HisLys: 0.373 ± 0.02	2.36HisLeu: 2.36 ± 0.048	0.364HisMet: 0.364 ± 0.018	0.541HisAsn: 0.541 ± 0.024	1.516HisPro: 1.516 ± 0.042	0.65HisGln: 0.65 ± 0.024	1.725HisArg: 1.725 ± 0.046	1.129HisSer: 1.129 ± 0.034	1.177HisThr: 1.177 ± 0.032	1.92HisVal: 1.92 ± 0.05	0.366HisTrp: 0.366 ± 0.019	0.496HisTyr: 0.496 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	5.145IleAla: 5.145 ± 0.078	0.298IleCys: 0.298 ± 0.016	2.81IleAsp: 2.81 ± 0.055	2.474IleGlu: 2.474 ± 0.059	1.082IlePhe: 1.082 ± 0.042	4.018IleGly: 4.018 ± 0.079	0.826IleHis: 0.826 ± 0.031	1.702IleIle: 1.702 ± 0.046	0.838IleLys: 0.838 ± 0.029	3.248IleLeu: 3.248 ± 0.066	0.683IleMet: 0.683 ± 0.026	1.084IleAsn: 1.084 ± 0.032	2.059IlePro: 2.059 ± 0.049	1.029IleGln: 1.029 ± 0.029	2.587IleArg: 2.587 ± 0.048	2.465IleSer: 2.465 ± 0.05	2.66IleThr: 2.66 ± 0.058	3.455IleVal: 3.455 ± 0.065	0.555IleTrp: 0.555 ± 0.025	0.765IleTyr: 0.765 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	2.357LysAla: 2.357 ± 0.05	0.1LysCys: 0.1 ± 0.009	1.129LysAsp: 1.129 ± 0.033	1.146LysGlu: 1.146 ± 0.036	0.642LysPhe: 0.642 ± 0.025	1.647LysGly: 1.647 ± 0.046	0.499LysHis: 0.499 ± 0.021	0.826LysIle: 0.826 ± 0.033	0.723LysLys: 0.723 ± 0.036	2.187LysLeu: 2.187 ± 0.046	0.438LysMet: 0.438 ± 0.023	0.502LysAsn: 0.502 ± 0.022	1.141LysPro: 1.141 ± 0.037	0.783LysGln: 0.783 ± 0.033	1.393LysArg: 1.393 ± 0.043	1.241LysSer: 1.241 ± 0.04	1.103LysThr: 1.103 ± 0.033	2.044LysVal: 2.044 ± 0.055	0.335LysTrp: 0.335 ± 0.016	0.5LysTyr: 0.5 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	13.995LeuAla: 13.995 ± 0.159	0.608LeuCys: 0.608 ± 0.026	6.405LeuAsp: 6.405 ± 0.091	5.899LeuGlu: 5.899 ± 0.079	2.871LeuPhe: 2.871 ± 0.064	9.799LeuGly: 9.799 ± 0.103	2.052LeuHis: 2.052 ± 0.047	3.22LeuIle: 3.22 ± 0.062	1.816LeuLys: 1.816 ± 0.048	10.441LeuLeu: 10.441 ± 0.144	1.832LeuMet: 1.832 ± 0.049	2.065LeuAsn: 2.065 ± 0.044	5.69LeuPro: 5.69 ± 0.066	2.646LeuGln: 2.646 ± 0.054	7.388LeuArg: 7.388 ± 0.107	5.352LeuSer: 5.352 ± 0.067	6.108LeuThr: 6.108 ± 0.08	10.135LeuVal: 10.135 ± 0.114	1.258LeuTrp: 1.258 ± 0.041	1.607LeuTyr: 1.607 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	2.667MetAla: 2.667 ± 0.046	0.132MetCys: 0.132 ± 0.011	1.013MetAsp: 1.013 ± 0.037	0.92MetGlu: 0.92 ± 0.03	0.575MetPhe: 0.575 ± 0.026	1.677MetGly: 1.677 ± 0.046	0.371MetHis: 0.371 ± 0.021	0.783MetIle: 0.783 ± 0.031	0.488MetLys: 0.488 ± 0.022	2.072MetLeu: 2.072 ± 0.047	0.399MetMet: 0.399 ± 0.021	0.529MetAsn: 0.529 ± 0.023	1.137MetPro: 1.137 ± 0.031	0.549MetGln: 0.549 ± 0.021	1.452MetArg: 1.452 ± 0.038	1.47MetSer: 1.47 ± 0.04	1.6MetThr: 1.6 ± 0.042	1.773MetVal: 1.773 ± 0.042	0.257MetTrp: 0.257 ± 0.017	0.32MetTyr: 0.32 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.439AsnAla: 2.439 ± 0.051	0.147AsnCys: 0.147 ± 0.012	1.233AsnAsp: 1.233 ± 0.037	1.19AsnGlu: 1.19 ± 0.034	0.758AsnPhe: 0.758 ± 0.029	2.074AsnGly: 2.074 ± 0.055	0.568AsnHis: 0.568 ± 0.022	0.958AsnIle: 0.958 ± 0.028	0.487AsnLys: 0.487 ± 0.023	2.317AsnLeu: 2.317 ± 0.05	0.499AsnMet: 0.499 ± 0.021	0.7AsnAsn: 0.7 ± 0.032	1.746AsnPro: 1.746 ± 0.039	0.754AsnGln: 0.754 ± 0.03	1.544AsnArg: 1.544 ± 0.038	1.246AsnSer: 1.246 ± 0.035	1.428AsnThr: 1.428 ± 0.033	1.851AsnVal: 1.851 ± 0.044	0.442AsnTrp: 0.442 ± 0.021	0.614AsnTyr: 0.614 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	6.328ProAla: 6.328 ± 0.092	0.255ProCys: 0.255 ± 0.018	4.071ProAsp: 4.071 ± 0.072	4.474ProGlu: 4.474 ± 0.07	1.657ProPhe: 1.657 ± 0.044	5.47ProGly: 5.47 ± 0.079	1.127ProHis: 1.127 ± 0.032	1.83ProIle: 1.83 ± 0.043	1.097ProLys: 1.097 ± 0.033	4.577ProLeu: 4.577 ± 0.066	1.047ProMet: 1.047 ± 0.033	1.228ProAsn: 1.228 ± 0.033	2.509ProPro: 2.509 ± 0.063	1.661ProGln: 1.661 ± 0.045	3.244ProArg: 3.244 ± 0.049	3.411ProSer: 3.411 ± 0.076	3.675ProThr: 3.675 ± 0.066	4.754ProVal: 4.754 ± 0.07	0.909ProTrp: 0.909 ± 0.031	1.068ProTyr: 1.068 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.601GlnAla: 3.601 ± 0.059	0.136GlnCys: 0.136 ± 0.01	1.387GlnAsp: 1.387 ± 0.039	1.637GlnGlu: 1.637 ± 0.042	0.999GlnPhe: 0.999 ± 0.029	2.34GlnGly: 2.34 ± 0.042	0.715GlnHis: 0.715 ± 0.028	1.246GlnIle: 1.246 ± 0.037	0.548GlnLys: 0.548 ± 0.026	3.585GlnLeu: 3.585 ± 0.072	0.597GlnMet: 0.597 ± 0.024	0.609GlnAsn: 0.609 ± 0.021	1.814GlnPro: 1.814 ± 0.047	1.4GlnGln: 1.4 ± 0.044	2.357GlnArg: 2.357 ± 0.05	1.519GlnSer: 1.519 ± 0.038	1.459GlnThr: 1.459 ± 0.04	2.861GlnVal: 2.861 ± 0.056	0.616GlnTrp: 0.616 ± 0.024	0.675GlnTyr: 0.675 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	8.07ArgAla: 8.07 ± 0.125	0.477ArgCys: 0.477 ± 0.023	4.049ArgAsp: 4.049 ± 0.073	4.315ArgGlu: 4.315 ± 0.074	2.469ArgPhe: 2.469 ± 0.05	5.31ArgGly: 5.31 ± 0.079	1.649ArgHis: 1.649 ± 0.038	3.428ArgIle: 3.428 ± 0.06	1.606ArgLys: 1.606 ± 0.04	7.234ArgLeu: 7.234 ± 0.101	1.664ArgMet: 1.664 ± 0.041	1.671ArgAsn: 1.671 ± 0.041	3.841ArgPro: 3.841 ± 0.067	2.207ArgGln: 2.207 ± 0.053	6.675ArgArg: 6.675 ± 0.118	4.04ArgSer: 4.04 ± 0.059	4.256ArgThr: 4.256 ± 0.071	5.612ArgVal: 5.612 ± 0.089	1.275ArgTrp: 1.275 ± 0.043	1.437ArgTyr: 1.437 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	6.092SerAla: 6.092 ± 0.077	0.336SerCys: 0.336 ± 0.022	3.23SerAsp: 3.23 ± 0.064	3.236SerGlu: 3.236 ± 0.061	1.89SerPhe: 1.89 ± 0.044	5.811SerGly: 5.811 ± 0.074	1.138SerHis: 1.138 ± 0.031	2.166SerIle: 2.166 ± 0.048	1.223SerLys: 1.223 ± 0.036	5.245SerLeu: 5.245 ± 0.067	1.339SerMet: 1.339 ± 0.039	1.381SerAsn: 1.381 ± 0.036	3.181SerPro: 3.181 ± 0.062	1.688SerGln: 1.688 ± 0.039	3.873SerArg: 3.873 ± 0.075	3.304SerSer: 3.304 ± 0.068	3.353SerThr: 3.353 ± 0.057	4.513SerVal: 4.513 ± 0.07	1.069SerTrp: 1.069 ± 0.032	1.285SerTyr: 1.285 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	7.049ThrAla: 7.049 ± 0.089	0.409ThrCys: 0.409 ± 0.022	3.724ThrAsp: 3.724 ± 0.067	3.259ThrGlu: 3.259 ± 0.054	1.982ThrPhe: 1.982 ± 0.048	5.802ThrGly: 5.802 ± 0.083	1.209ThrHis: 1.209 ± 0.034	2.599ThrIle: 2.599 ± 0.062	1.251ThrLys: 1.251 ± 0.034	5.461ThrLeu: 5.461 ± 0.072	1.206ThrMet: 1.206 ± 0.033	1.386ThrAsn: 1.386 ± 0.036	3.802ThrPro: 3.802 ± 0.073	1.666ThrGln: 1.666 ± 0.043	3.769ThrArg: 3.769 ± 0.061	3.49ThrSer: 3.49 ± 0.061	4.081ThrThr: 4.081 ± 0.071	5.6ThrVal: 5.6 ± 0.092	1.071ThrTrp: 1.071 ± 0.036	1.357ThrTyr: 1.357 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	11.981ValAla: 11.981 ± 0.125	0.614ValCys: 0.614 ± 0.026	5.762ValAsp: 5.762 ± 0.085	5.697ValGlu: 5.697 ± 0.078	2.776ValPhe: 2.776 ± 0.058	7.643ValGly: 7.643 ± 0.091	1.895ValHis: 1.895 ± 0.042	3.612ValIle: 3.612 ± 0.073	1.589ValLys: 1.589 ± 0.04	9.439ValLeu: 9.439 ± 0.114	1.727ValMet: 1.727 ± 0.045	2.085ValAsn: 2.085 ± 0.049	4.836ValPro: 4.836 ± 0.068	2.215ValGln: 2.215 ± 0.049	5.896ValArg: 5.896 ± 0.079	4.968ValSer: 4.968 ± 0.07	5.815ValThr: 5.815 ± 0.085	9.693ValVal: 9.693 ± 0.133	1.294ValTrp: 1.294 ± 0.037	1.367ValTyr: 1.367 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.745TrpAla: 1.745 ± 0.047	0.135TrpCys: 0.135 ± 0.012	0.97TrpAsp: 0.97 ± 0.034	0.806TrpGlu: 0.806 ± 0.026	0.656TrpPhe: 0.656 ± 0.022	1.218TrpGly: 1.218 ± 0.036	0.381TrpHis: 0.381 ± 0.019	0.587TrpIle: 0.587 ± 0.025	0.332TrpLys: 0.332 ± 0.019	1.989TrpLeu: 1.989 ± 0.049	0.342TrpMet: 0.342 ± 0.018	0.474TrpAsn: 0.474 ± 0.025	0.799TrpPro: 0.799 ± 0.03	0.637TrpGln: 0.637 ± 0.022	1.362TrpArg: 1.362 ± 0.043	1.006TrpSer: 1.006 ± 0.034	1.051TrpThr: 1.051 ± 0.032	1.424TrpVal: 1.424 ± 0.04	0.418TrpTrp: 0.418 ± 0.023	0.38TrpTyr: 0.38 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.138TyrAla: 2.138 ± 0.042	0.16TyrCys: 0.16 ± 0.012	1.278TyrAsp: 1.278 ± 0.036	1.227TyrGlu: 1.227 ± 0.041	0.767TyrPhe: 0.767 ± 0.029	1.838TyrGly: 1.838 ± 0.043	0.381TyrHis: 0.381 ± 0.02	0.61TyrIle: 0.61 ± 0.025	0.375TyrLys: 0.375 ± 0.021	2.204TyrLeu: 2.204 ± 0.05	0.326TyrMet: 0.326 ± 0.018	0.523TyrAsn: 0.523 ± 0.023	1.013TyrPro: 1.013 ± 0.032	0.629TyrGln: 0.629 ± 0.028	1.581TyrArg: 1.581 ± 0.037	1.229TyrSer: 1.229 ± 0.037	1.118TyrThr: 1.118 ± 0.043	1.663TyrVal: 1.663 ± 0.043	0.357TyrTrp: 0.357 ± 0.017	0.508TyrTyr: 0.508 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3082 proteins (1069584 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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