Amino acid dipepetide frequency for Aureobasidium subglaciale (strain EXF-2481) (Aureobasidium pullulans var. subglaciale)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.317AlaAla: 9.317 ± 0.064	1.151AlaCys: 1.151 ± 0.016	4.394AlaAsp: 4.394 ± 0.031	5.127AlaGlu: 5.127 ± 0.041	3.301AlaPhe: 3.301 ± 0.028	5.752AlaGly: 5.752 ± 0.04	1.875AlaHis: 1.875 ± 0.018	4.357AlaIle: 4.357 ± 0.03	4.229AlaLys: 4.229 ± 0.035	7.885AlaLeu: 7.885 ± 0.05	2.055AlaMet: 2.055 ± 0.021	3.167AlaAsn: 3.167 ± 0.027	5.017AlaPro: 5.017 ± 0.048	3.718AlaGln: 3.718 ± 0.037	4.834AlaArg: 4.834 ± 0.029	7.752AlaSer: 7.752 ± 0.057	5.519AlaThr: 5.519 ± 0.039	5.467AlaVal: 5.467 ± 0.034	1.185AlaTrp: 1.185 ± 0.017	2.338AlaTyr: 2.338 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.986CysAla: 0.986 ± 0.018	0.256CysCys: 0.256 ± 0.008	0.674CysAsp: 0.674 ± 0.013	0.601CysGlu: 0.601 ± 0.012	0.558CysPhe: 0.558 ± 0.012	0.932CysGly: 0.932 ± 0.018	0.33CysHis: 0.33 ± 0.009	0.737CysIle: 0.737 ± 0.013	0.553CysLys: 0.553 ± 0.012	1.276CysLeu: 1.276 ± 0.018	0.289CysMet: 0.289 ± 0.008	0.475CysAsn: 0.475 ± 0.01	0.659CysPro: 0.659 ± 0.014	0.457CysGln: 0.457 ± 0.01	0.722CysArg: 0.722 ± 0.013	1.003CysSer: 1.003 ± 0.016	0.732CysThr: 0.732 ± 0.013	0.809CysVal: 0.809 ± 0.013	0.196CysTrp: 0.196 ± 0.006	0.366CysTyr: 0.366 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.95AspAla: 4.95 ± 0.037	0.647AspCys: 0.647 ± 0.011	4.394AspAsp: 4.394 ± 0.042	4.475AspGlu: 4.475 ± 0.038	2.318AspPhe: 2.318 ± 0.023	3.792AspGly: 3.792 ± 0.033	1.311AspHis: 1.311 ± 0.017	3.024AspIle: 3.024 ± 0.026	2.556AspLys: 2.556 ± 0.028	5.118AspLeu: 5.118 ± 0.04	1.436AspMet: 1.436 ± 0.016	2.007AspAsn: 2.007 ± 0.023	3.112AspPro: 3.112 ± 0.025	2.05AspGln: 2.05 ± 0.023	2.934AspArg: 2.934 ± 0.026	4.129AspSer: 4.129 ± 0.031	3.146AspThr: 3.146 ± 0.029	3.803AspVal: 3.803 ± 0.031	0.902AspTrp: 0.902 ± 0.015	1.658AspTyr: 1.658 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	5.337GluAla: 5.337 ± 0.038	0.572GluCys: 0.572 ± 0.012	4.263GluAsp: 4.263 ± 0.04	5.143GluGlu: 5.143 ± 0.057	1.798GluPhe: 1.798 ± 0.023	3.539GluGly: 3.539 ± 0.031	1.472GluHis: 1.472 ± 0.018	2.853GluIle: 2.853 ± 0.028	3.667GluLys: 3.667 ± 0.036	4.921GluLeu: 4.921 ± 0.038	1.478GluMet: 1.478 ± 0.018	2.109GluAsn: 2.109 ± 0.022	2.521GluPro: 2.521 ± 0.026	2.656GluGln: 2.656 ± 0.028	3.664GluArg: 3.664 ± 0.034	4.112GluSer: 4.112 ± 0.031	3.377GluThr: 3.377 ± 0.029	3.468GluVal: 3.468 ± 0.028	0.838GluTrp: 0.838 ± 0.012	1.611GluTyr: 1.611 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.322PheAla: 3.322 ± 0.03	0.585PheCys: 0.585 ± 0.012	2.345PheAsp: 2.345 ± 0.02	2.172PheGlu: 2.172 ± 0.023	1.662PhePhe: 1.662 ± 0.023	2.94PheGly: 2.94 ± 0.03	0.841PheHis: 0.841 ± 0.013	1.763PheIle: 1.763 ± 0.022	1.538PheLys: 1.538 ± 0.019	3.318PheLeu: 3.318 ± 0.03	0.819PheMet: 0.819 ± 0.012	1.472PheAsn: 1.472 ± 0.018	1.804PhePro: 1.804 ± 0.021	1.3PheGln: 1.3 ± 0.012	1.829PheArg: 1.829 ± 0.019	3.071PheSer: 3.071 ± 0.027	2.202PheThr: 2.202 ± 0.021	2.496PheVal: 2.496 ± 0.024	0.639PheTrp: 0.639 ± 0.012	1.088PheTyr: 1.088 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.266GlyAla: 5.266 ± 0.037	0.886GlyCys: 0.886 ± 0.017	3.451GlyAsp: 3.451 ± 0.028	3.328GlyGlu: 3.328 ± 0.033	2.757GlyPhe: 2.757 ± 0.027	5.33GlyGly: 5.33 ± 0.062	1.616GlyHis: 1.616 ± 0.018	3.405GlyIle: 3.405 ± 0.033	3.398GlyLys: 3.398 ± 0.034	5.916GlyLeu: 5.916 ± 0.043	1.639GlyMet: 1.639 ± 0.021	2.488GlyAsn: 2.488 ± 0.025	3.026GlyPro: 3.026 ± 0.032	2.556GlyGln: 2.556 ± 0.03	3.768GlyArg: 3.768 ± 0.031	5.391GlySer: 5.391 ± 0.045	3.826GlyThr: 3.826 ± 0.035	4.276GlyVal: 4.276 ± 0.034	1.131GlyTrp: 1.131 ± 0.017	2.132GlyTyr: 2.132 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	1.965HisAla: 1.965 ± 0.021	0.348HisCys: 0.348 ± 0.008	1.449HisAsp: 1.449 ± 0.019	1.364HisGlu: 1.364 ± 0.017	0.936HisPhe: 0.936 ± 0.016	1.621HisGly: 1.621 ± 0.02	0.867HisHis: 0.867 ± 0.017	1.215HisIle: 1.215 ± 0.015	1.006HisLys: 1.006 ± 0.016	2.26HisLeu: 2.26 ± 0.026	0.554HisMet: 0.554 ± 0.011	0.934HisAsn: 0.934 ± 0.015	1.559HisPro: 1.559 ± 0.019	0.999HisGln: 0.999 ± 0.016	1.441HisArg: 1.441 ± 0.022	1.86HisSer: 1.86 ± 0.025	1.41HisThr: 1.41 ± 0.02	1.517HisVal: 1.517 ± 0.018	0.344HisTrp: 0.344 ± 0.009	0.699HisTyr: 0.699 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.4IleAla: 4.4 ± 0.039	0.744IleCys: 0.744 ± 0.012	2.94IleAsp: 2.94 ± 0.026	2.819IleGlu: 2.819 ± 0.023	1.971IlePhe: 1.971 ± 0.025	3.212IleGly: 3.212 ± 0.033	1.177IleHis: 1.177 ± 0.015	2.505IleIle: 2.505 ± 0.028	2.36IleLys: 2.36 ± 0.023	4.299IleLeu: 4.299 ± 0.033	1.096IleMet: 1.096 ± 0.016	1.927IleAsn: 1.927 ± 0.023	2.848IlePro: 2.848 ± 0.026	1.824IleGln: 1.824 ± 0.022	2.632IleArg: 2.632 ± 0.025	3.967IleSer: 3.967 ± 0.034	2.963IleThr: 2.963 ± 0.025	3.228IleVal: 3.228 ± 0.028	0.729IleTrp: 0.729 ± 0.013	1.408IleTyr: 1.408 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.451LysAla: 4.451 ± 0.036	0.505LysCys: 0.505 ± 0.012	2.993LysAsp: 2.993 ± 0.026	3.278LysGlu: 3.278 ± 0.038	1.437LysPhe: 1.437 ± 0.018	2.911LysGly: 2.911 ± 0.03	1.251LysHis: 1.251 ± 0.018	2.325LysIle: 2.325 ± 0.023	3.413LysLys: 3.413 ± 0.042	4.062LysLeu: 4.062 ± 0.037	1.06LysMet: 1.06 ± 0.014	1.818LysAsn: 1.818 ± 0.021	2.72LysPro: 2.72 ± 0.027	2.094LysGln: 2.094 ± 0.023	3.39LysArg: 3.39 ± 0.029	3.65LysSer: 3.65 ± 0.032	3.096LysThr: 3.096 ± 0.03	2.905LysVal: 2.905 ± 0.031	0.666LysTrp: 0.666 ± 0.011	1.358LysTyr: 1.358 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	7.856LeuAla: 7.856 ± 0.047	1.255LeuCys: 1.255 ± 0.018	5.301LeuAsp: 5.301 ± 0.037	5.287LeuGlu: 5.287 ± 0.041	3.295LeuPhe: 3.295 ± 0.032	5.665LeuGly: 5.665 ± 0.034	2.217LeuHis: 2.217 ± 0.022	3.901LeuIle: 3.901 ± 0.034	4.131LeuLys: 4.131 ± 0.035	8.111LeuLeu: 8.111 ± 0.059	1.803LeuMet: 1.803 ± 0.018	3.218LeuAsn: 3.218 ± 0.028	5.461LeuPro: 5.461 ± 0.044	3.779LeuGln: 3.779 ± 0.039	5.511LeuArg: 5.511 ± 0.039	7.359LeuSer: 7.359 ± 0.054	4.901LeuThr: 4.901 ± 0.033	5.292LeuVal: 5.292 ± 0.04	1.157LeuTrp: 1.157 ± 0.016	2.356LeuTyr: 2.356 ± 0.02	0.0LeuXaa: 0.0 ± 0.0
Met	2.26MetAla: 2.26 ± 0.023	0.256MetCys: 0.256 ± 0.007	1.306MetAsp: 1.306 ± 0.016	1.186MetGlu: 1.186 ± 0.016	0.817MetPhe: 0.817 ± 0.015	1.421MetGly: 1.421 ± 0.019	0.565MetHis: 0.565 ± 0.011	1.062MetIle: 1.062 ± 0.015	0.982MetLys: 0.982 ± 0.016	1.984MetLeu: 1.984 ± 0.026	0.613MetMet: 0.613 ± 0.013	0.854MetAsn: 0.854 ± 0.014	1.417MetPro: 1.417 ± 0.017	0.988MetGln: 0.988 ± 0.016	1.286MetArg: 1.286 ± 0.017	2.14MetSer: 2.14 ± 0.023	1.386MetThr: 1.386 ± 0.018	1.355MetVal: 1.355 ± 0.016	0.262MetTrp: 0.262 ± 0.007	0.575MetTyr: 0.575 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.358AsnAla: 3.358 ± 0.031	0.434AsnCys: 0.434 ± 0.011	2.085AsnAsp: 2.085 ± 0.023	1.955AsnGlu: 1.955 ± 0.02	1.458AsnPhe: 1.458 ± 0.016	2.806AsnGly: 2.806 ± 0.026	0.904AsnHis: 0.904 ± 0.015	2.164AsnIle: 2.164 ± 0.022	1.776AsnLys: 1.776 ± 0.022	3.306AsnLeu: 3.306 ± 0.028	0.946AsnMet: 0.946 ± 0.015	1.679AsnAsn: 1.679 ± 0.025	2.328AsnPro: 2.328 ± 0.024	1.378AsnGln: 1.378 ± 0.017	1.824AsnArg: 1.824 ± 0.02	2.87AsnSer: 2.87 ± 0.028	2.444AsnThr: 2.444 ± 0.026	2.416AsnVal: 2.416 ± 0.022	0.556AsnTrp: 0.556 ± 0.01	1.113AsnTyr: 1.113 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.268ProAla: 5.268 ± 0.044	0.522ProCys: 0.522 ± 0.012	3.047ProAsp: 3.047 ± 0.027	3.584ProGlu: 3.584 ± 0.033	2.015ProPhe: 2.015 ± 0.022	3.481ProGly: 3.481 ± 0.03	1.322ProHis: 1.322 ± 0.018	2.515ProIle: 2.515 ± 0.025	2.627ProLys: 2.627 ± 0.028	4.603ProLeu: 4.603 ± 0.034	1.104ProMet: 1.104 ± 0.017	2.107ProAsn: 2.107 ± 0.021	4.609ProPro: 4.609 ± 0.067	2.529ProGln: 2.529 ± 0.033	3.205ProArg: 3.205 ± 0.034	5.976ProSer: 5.976 ± 0.055	4.042ProThr: 4.042 ± 0.032	3.469ProVal: 3.469 ± 0.03	0.686ProTrp: 0.686 ± 0.012	1.534ProTyr: 1.534 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.69GlnAla: 3.69 ± 0.035	0.454GlnCys: 0.454 ± 0.01	2.294GlnAsp: 2.294 ± 0.024	2.446GlnGlu: 2.446 ± 0.027	1.236GlnPhe: 1.236 ± 0.016	2.436GlnGly: 2.436 ± 0.025	1.222GlnHis: 1.222 ± 0.018	1.942GlnIle: 1.942 ± 0.018	2.082GlnLys: 2.082 ± 0.024	3.402GlnLeu: 3.402 ± 0.028	0.951GlnMet: 0.951 ± 0.017	1.639GlnAsn: 1.639 ± 0.023	2.559GlnPro: 2.559 ± 0.031	2.873GlnGln: 2.873 ± 0.058	2.654GlnArg: 2.654 ± 0.029	3.338GlnSer: 3.338 ± 0.035	2.53GlnThr: 2.53 ± 0.023	2.171GlnVal: 2.171 ± 0.021	0.559GlnTrp: 0.559 ± 0.011	1.203GlnTyr: 1.203 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.563ArgAla: 4.563 ± 0.03	0.722ArgCys: 0.722 ± 0.014	3.219ArgAsp: 3.219 ± 0.031	3.514ArgGlu: 3.514 ± 0.033	2.046ArgPhe: 2.046 ± 0.022	3.417ArgGly: 3.417 ± 0.035	1.529ArgHis: 1.529 ± 0.018	2.781ArgIle: 2.781 ± 0.026	3.454ArgLys: 3.454 ± 0.028	5.218ArgLeu: 5.218 ± 0.042	1.325ArgMet: 1.325 ± 0.016	2.244ArgAsn: 2.244 ± 0.024	3.365ArgPro: 3.365 ± 0.037	2.664ArgGln: 2.664 ± 0.027	4.664ArgArg: 4.664 ± 0.051	4.713ArgSer: 4.713 ± 0.034	3.24ArgThr: 3.24 ± 0.027	3.201ArgVal: 3.201 ± 0.027	0.844ArgTrp: 0.844 ± 0.014	1.575ArgTyr: 1.575 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	7.269SerAla: 7.269 ± 0.059	0.966SerCys: 0.966 ± 0.017	4.398SerAsp: 4.398 ± 0.035	4.06SerGlu: 4.06 ± 0.029	3.067SerPhe: 3.067 ± 0.028	5.471SerGly: 5.471 ± 0.044	1.983SerHis: 1.983 ± 0.022	4.144SerIle: 4.144 ± 0.035	3.816SerLys: 3.816 ± 0.034	7.259SerLeu: 7.259 ± 0.051	1.842SerMet: 1.842 ± 0.018	3.198SerAsn: 3.198 ± 0.028	5.411SerPro: 5.411 ± 0.048	3.322SerGln: 3.322 ± 0.036	4.92SerArg: 4.92 ± 0.038	9.331SerSer: 9.331 ± 0.106	6.071SerThr: 6.071 ± 0.055	4.775SerVal: 4.775 ± 0.04	1.104SerTrp: 1.104 ± 0.018	2.165SerTyr: 2.165 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	5.469ThrAla: 5.469 ± 0.037	0.81ThrCys: 0.81 ± 0.015	2.919ThrAsp: 2.919 ± 0.031	3.044ThrGlu: 3.044 ± 0.027	2.349ThrPhe: 2.349 ± 0.024	4.058ThrGly: 4.058 ± 0.035	1.37ThrHis: 1.37 ± 0.018	3.269ThrIle: 3.269 ± 0.03	2.817ThrLys: 2.817 ± 0.03	5.405ThrLeu: 5.405 ± 0.036	1.266ThrMet: 1.266 ± 0.016	2.337ThrAsn: 2.337 ± 0.022	4.323ThrPro: 4.323 ± 0.038	2.296ThrGln: 2.296 ± 0.02	3.219ThrArg: 3.219 ± 0.027	5.882ThrSer: 5.882 ± 0.054	4.614ThrThr: 4.614 ± 0.049	3.749ThrVal: 3.749 ± 0.028	0.859ThrTrp: 0.859 ± 0.015	1.698ThrTyr: 1.698 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	5.324ValAla: 5.324 ± 0.038	0.845ValCys: 0.845 ± 0.016	3.747ValAsp: 3.747 ± 0.027	3.761ValGlu: 3.761 ± 0.031	2.458ValPhe: 2.458 ± 0.021	3.871ValGly: 3.871 ± 0.037	1.391ValHis: 1.391 ± 0.016	2.905ValIle: 2.905 ± 0.027	3.033ValLys: 3.033 ± 0.03	5.517ValLeu: 5.517 ± 0.042	1.393ValMet: 1.393 ± 0.016	2.277ValAsn: 2.277 ± 0.022	3.425ValPro: 3.425 ± 0.03	2.466ValGln: 2.466 ± 0.024	3.356ValArg: 3.356 ± 0.027	4.805ValSer: 4.805 ± 0.039	3.574ValThr: 3.574 ± 0.032	4.227ValVal: 4.227 ± 0.035	0.87ValTrp: 0.87 ± 0.015	1.779ValTyr: 1.779 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.082TrpAla: 1.082 ± 0.017	0.212TrpCys: 0.212 ± 0.007	0.837TrpAsp: 0.837 ± 0.013	0.753TrpGlu: 0.753 ± 0.012	0.539TrpPhe: 0.539 ± 0.011	0.866TrpGly: 0.866 ± 0.014	0.355TrpHis: 0.355 ± 0.008	0.777TrpIle: 0.777 ± 0.015	0.786TrpLys: 0.786 ± 0.015	1.355TrpLeu: 1.355 ± 0.02	0.37TrpMet: 0.37 ± 0.009	0.63TrpAsn: 0.63 ± 0.012	0.59TrpPro: 0.59 ± 0.012	0.61TrpGln: 0.61 ± 0.01	0.907TrpArg: 0.907 ± 0.015	1.141TrpSer: 1.141 ± 0.017	0.927TrpThr: 0.927 ± 0.015	0.79TrpVal: 0.79 ± 0.014	0.271TrpTrp: 0.271 ± 0.008	0.43TrpTyr: 0.43 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.305TyrAla: 2.305 ± 0.023	0.439TyrCys: 0.439 ± 0.011	1.704TyrAsp: 1.704 ± 0.02	1.504TyrGlu: 1.504 ± 0.019	1.189TyrPhe: 1.189 ± 0.016	2.065TyrGly: 2.065 ± 0.026	0.754TyrHis: 0.754 ± 0.013	1.405TyrIle: 1.405 ± 0.018	1.161TyrLys: 1.161 ± 0.016	2.642TyrLeu: 2.642 ± 0.025	0.676TyrMet: 0.676 ± 0.012	1.217TyrAsn: 1.217 ± 0.02	1.491TyrPro: 1.491 ± 0.021	1.121TyrGln: 1.121 ± 0.017	1.542TyrArg: 1.542 ± 0.018	2.081TyrSer: 2.081 ± 0.023	1.752TyrThr: 1.752 ± 0.021	1.609TyrVal: 1.609 ± 0.018	0.43TyrTrp: 0.43 ± 0.01	0.946TyrTyr: 0.946 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10792 proteins (4879484 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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