Amino acid dipepetide frequency for Halomonas taeanensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.963AlaAla: 12.963 ± 0.146	1.193AlaCys: 1.193 ± 0.035	6.322AlaAsp: 6.322 ± 0.079	7.417AlaGlu: 7.417 ± 0.095	3.954AlaPhe: 3.954 ± 0.069	9.43AlaGly: 9.43 ± 0.12	2.269AlaHis: 2.269 ± 0.047	5.375AlaIle: 5.375 ± 0.075	3.38AlaLys: 3.38 ± 0.068	14.19AlaLeu: 14.19 ± 0.15	3.522AlaMet: 3.522 ± 0.058	2.806AlaAsn: 2.806 ± 0.06	5.095AlaPro: 5.095 ± 0.091	4.214AlaGln: 4.214 ± 0.068	7.888AlaArg: 7.888 ± 0.1	6.953AlaSer: 6.953 ± 0.099	5.412AlaThr: 5.412 ± 0.075	7.329AlaVal: 7.329 ± 0.081	1.882AlaTrp: 1.882 ± 0.044	2.414AlaTyr: 2.414 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.877CysAla: 0.877 ± 0.028	0.135CysCys: 0.135 ± 0.011	0.542CysAsp: 0.542 ± 0.021	0.548CysGlu: 0.548 ± 0.024	0.336CysPhe: 0.336 ± 0.018	0.939CysGly: 0.939 ± 0.035	0.331CysHis: 0.331 ± 0.017	0.365CysIle: 0.365 ± 0.018	0.217CysLys: 0.217 ± 0.015	1.067CysLeu: 1.067 ± 0.031	0.215CysMet: 0.215 ± 0.014	0.221CysAsn: 0.221 ± 0.015	0.512CysPro: 0.512 ± 0.026	0.401CysGln: 0.401 ± 0.02	0.705CysArg: 0.705 ± 0.025	0.468CysSer: 0.468 ± 0.024	0.371CysThr: 0.371 ± 0.019	0.629CysVal: 0.629 ± 0.025	0.145CysTrp: 0.145 ± 0.012	0.257CysTyr: 0.257 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	7.181AspAla: 7.181 ± 0.096	0.534AspCys: 0.534 ± 0.025	4.13AspAsp: 4.13 ± 0.103	4.327AspGlu: 4.327 ± 0.072	2.172AspPhe: 2.172 ± 0.047	4.918AspGly: 4.918 ± 0.074	1.455AspHis: 1.455 ± 0.04	3.044AspIle: 3.044 ± 0.054	1.707AspLys: 1.707 ± 0.045	5.714AspLeu: 5.714 ± 0.076	1.427AspMet: 1.427 ± 0.037	1.648AspAsn: 1.648 ± 0.042	2.979AspPro: 2.979 ± 0.057	2.319AspGln: 2.319 ± 0.046	3.617AspArg: 3.617 ± 0.056	2.963AspSer: 2.963 ± 0.056	3.093AspThr: 3.093 ± 0.07	3.931AspVal: 3.931 ± 0.067	1.101AspTrp: 1.101 ± 0.033	1.777AspTyr: 1.777 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	8.525GluAla: 8.525 ± 0.102	0.499GluCys: 0.499 ± 0.022	3.31GluAsp: 3.31 ± 0.059	3.76GluGlu: 3.76 ± 0.08	1.605GluPhe: 1.605 ± 0.034	4.9GluGly: 4.9 ± 0.087	1.754GluHis: 1.754 ± 0.042	2.927GluIle: 2.927 ± 0.063	1.829GluLys: 1.829 ± 0.05	6.888GluLeu: 6.888 ± 0.08	1.463GluMet: 1.463 ± 0.037	1.453GluAsn: 1.453 ± 0.04	2.768GluPro: 2.768 ± 0.061	3.124GluGln: 3.124 ± 0.056	5.823GluArg: 5.823 ± 0.083	3.308GluSer: 3.308 ± 0.058	3.273GluThr: 3.273 ± 0.066	4.685GluVal: 4.685 ± 0.072	0.776GluTrp: 0.776 ± 0.027	1.193GluTyr: 1.193 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.688PheAla: 3.688 ± 0.062	0.388PheCys: 0.388 ± 0.018	2.45PheAsp: 2.45 ± 0.047	2.089PheGlu: 2.089 ± 0.044	1.32PhePhe: 1.32 ± 0.045	3.093PheGly: 3.093 ± 0.053	0.788PheHis: 0.788 ± 0.024	1.661PheIle: 1.661 ± 0.043	0.99PheLys: 0.99 ± 0.03	3.169PheLeu: 3.169 ± 0.061	0.868PheMet: 0.868 ± 0.029	1.039PheAsn: 1.039 ± 0.03	1.411PhePro: 1.411 ± 0.04	1.11PheGln: 1.11 ± 0.031	1.86PheArg: 1.86 ± 0.044	2.286PheSer: 2.286 ± 0.055	1.93PheThr: 1.93 ± 0.04	2.287PheVal: 2.287 ± 0.052	0.488PheTrp: 0.488 ± 0.024	0.868PheTyr: 0.868 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	7.693GlyAla: 7.693 ± 0.101	0.92GlyCys: 0.92 ± 0.029	4.776GlyAsp: 4.776 ± 0.089	5.757GlyGlu: 5.757 ± 0.084	3.149GlyPhe: 3.149 ± 0.056	6.613GlyGly: 6.613 ± 0.129	2.118GlyHis: 2.118 ± 0.055	4.509GlyIle: 4.509 ± 0.081	2.849GlyLys: 2.849 ± 0.055	9.494GlyLeu: 9.494 ± 0.117	2.475GlyMet: 2.475 ± 0.049	2.194GlyAsn: 2.194 ± 0.065	2.794GlyPro: 2.794 ± 0.047	3.4GlyGln: 3.4 ± 0.066	5.522GlyArg: 5.522 ± 0.078	4.423GlySer: 4.423 ± 0.075	3.717GlyThr: 3.717 ± 0.066	6.179GlyVal: 6.179 ± 0.088	1.371GlyTrp: 1.371 ± 0.038	2.332GlyTyr: 2.332 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	2.401HisAla: 2.401 ± 0.049	0.295HisCys: 0.295 ± 0.018	1.562HisAsp: 1.562 ± 0.042	1.364HisGlu: 1.364 ± 0.039	1.014HisPhe: 1.014 ± 0.031	2.177HisGly: 2.177 ± 0.054	0.842HisHis: 0.842 ± 0.033	0.922HisIle: 0.922 ± 0.031	0.544HisLys: 0.544 ± 0.023	2.658HisLeu: 2.658 ± 0.059	0.452HisMet: 0.452 ± 0.022	0.552HisAsn: 0.552 ± 0.024	1.586HisPro: 1.586 ± 0.042	1.107HisGln: 1.107 ± 0.037	1.741HisArg: 1.741 ± 0.034	1.133HisSer: 1.133 ± 0.03	0.941HisThr: 0.941 ± 0.028	1.418HisVal: 1.418 ± 0.032	0.448HisTrp: 0.448 ± 0.021	0.762HisTyr: 0.762 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.724IleAla: 5.724 ± 0.076	0.436IleCys: 0.436 ± 0.018	3.659IleAsp: 3.659 ± 0.058	3.569IleGlu: 3.569 ± 0.062	1.452IlePhe: 1.452 ± 0.042	4.423IleGly: 4.423 ± 0.077	0.984IleHis: 0.984 ± 0.028	2.037IleIle: 2.037 ± 0.051	1.437IleLys: 1.437 ± 0.042	3.879IleLeu: 3.879 ± 0.068	0.93IleMet: 0.93 ± 0.032	1.617IleAsn: 1.617 ± 0.037	2.053IlePro: 2.053 ± 0.046	1.465IleGln: 1.465 ± 0.035	2.822IleArg: 2.822 ± 0.056	2.775IleSer: 2.775 ± 0.062	2.672IleThr: 2.672 ± 0.048	3.041IleVal: 3.041 ± 0.063	0.45IleTrp: 0.45 ± 0.02	1.041IleTyr: 1.041 ± 0.033	0.0IleXaa: 0.0 ± 0.0
Lys	3.619LysAla: 3.619 ± 0.061	0.157LysCys: 0.157 ± 0.012	1.57LysAsp: 1.57 ± 0.044	1.652LysGlu: 1.652 ± 0.045	0.649LysPhe: 0.649 ± 0.024	2.348LysGly: 2.348 ± 0.049	0.656LysHis: 0.656 ± 0.023	1.16LysIle: 1.16 ± 0.036	1.072LysLys: 1.072 ± 0.038	2.908LysLeu: 2.908 ± 0.057	0.654LysMet: 0.654 ± 0.025	0.72LysAsn: 0.72 ± 0.031	1.541LysPro: 1.541 ± 0.041	1.239LysGln: 1.239 ± 0.043	2.541LysArg: 2.541 ± 0.062	1.581LysSer: 1.581 ± 0.04	1.471LysThr: 1.471 ± 0.036	2.28LysVal: 2.28 ± 0.052	0.291LysTrp: 0.291 ± 0.016	0.512LysTyr: 0.512 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	14.706LeuAla: 14.706 ± 0.152	1.113LeuCys: 1.113 ± 0.031	7.439LeuAsp: 7.439 ± 0.099	7.627LeuGlu: 7.627 ± 0.097	3.524LeuPhe: 3.524 ± 0.065	9.519LeuGly: 9.519 ± 0.121	2.27LeuHis: 2.27 ± 0.049	5.43LeuIle: 5.43 ± 0.078	3.753LeuLys: 3.753 ± 0.058	11.957LeuLeu: 11.957 ± 0.144	3.032LeuMet: 3.032 ± 0.054	2.943LeuAsn: 2.943 ± 0.056	6.181LeuPro: 6.181 ± 0.078	2.984LeuGln: 2.984 ± 0.052	6.634LeuArg: 6.634 ± 0.09	7.348LeuSer: 7.348 ± 0.104	6.073LeuThr: 6.073 ± 0.074	8.107LeuVal: 8.107 ± 0.11	1.463LeuTrp: 1.463 ± 0.047	2.349LeuTyr: 2.349 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	3.284MetAla: 3.284 ± 0.062	0.174MetCys: 0.174 ± 0.014	1.174MetAsp: 1.174 ± 0.033	1.15MetGlu: 1.15 ± 0.032	0.699MetPhe: 0.699 ± 0.029	1.909MetGly: 1.909 ± 0.041	0.519MetHis: 0.519 ± 0.024	1.314MetIle: 1.314 ± 0.041	0.812MetLys: 0.812 ± 0.029	2.84MetLeu: 2.84 ± 0.056	0.679MetMet: 0.679 ± 0.022	0.781MetAsn: 0.781 ± 0.024	1.455MetPro: 1.455 ± 0.038	0.978MetGln: 0.978 ± 0.034	1.689MetArg: 1.689 ± 0.04	1.849MetSer: 1.849 ± 0.037	1.794MetThr: 1.794 ± 0.041	1.72MetVal: 1.72 ± 0.044	0.193MetTrp: 0.193 ± 0.014	0.327MetTyr: 0.327 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.084AsnAla: 3.084 ± 0.051	0.21AsnCys: 0.21 ± 0.014	1.683AsnAsp: 1.683 ± 0.054	1.372AsnGlu: 1.372 ± 0.039	0.856AsnPhe: 0.856 ± 0.028	2.166AsnGly: 2.166 ± 0.05	0.58AsnHis: 0.58 ± 0.019	1.297AsnIle: 1.297 ± 0.039	0.614AsnLys: 0.614 ± 0.027	2.738AsnLeu: 2.738 ± 0.061	0.566AsnMet: 0.566 ± 0.025	0.709AsnAsn: 0.709 ± 0.028	1.61AsnPro: 1.61 ± 0.041	1.035AsnGln: 1.035 ± 0.033	1.859AsnArg: 1.859 ± 0.043	1.217AsnSer: 1.217 ± 0.035	1.254AsnThr: 1.254 ± 0.034	1.767AsnVal: 1.767 ± 0.042	0.355AsnTrp: 0.355 ± 0.021	0.676AsnTyr: 0.676 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	5.457ProAla: 5.457 ± 0.082	0.341ProCys: 0.341 ± 0.018	3.25ProAsp: 3.25 ± 0.068	3.812ProGlu: 3.812 ± 0.066	1.692ProPhe: 1.692 ± 0.041	4.201ProGly: 4.201 ± 0.07	1.1ProHis: 1.1 ± 0.035	1.886ProIle: 1.886 ± 0.047	1.341ProLys: 1.341 ± 0.033	5.57ProLeu: 5.57 ± 0.079	1.188ProMet: 1.188 ± 0.032	1.202ProAsn: 1.202 ± 0.037	2.07ProPro: 2.07 ± 0.051	1.859ProGln: 1.859 ± 0.042	2.883ProArg: 2.883 ± 0.055	2.962ProSer: 2.962 ± 0.045	2.245ProThr: 2.245 ± 0.05	3.692ProVal: 3.692 ± 0.057	0.812ProTrp: 0.812 ± 0.024	1.072ProTyr: 1.072 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	5.638GlnAla: 5.638 ± 0.096	0.315GlnCys: 0.315 ± 0.02	2.003GlnAsp: 2.003 ± 0.049	2.26GlnGlu: 2.26 ± 0.055	1.031GlnPhe: 1.031 ± 0.029	3.373GlnGly: 3.373 ± 0.064	0.979GlnHis: 0.979 ± 0.03	1.438GlnIle: 1.438 ± 0.039	0.904GlnLys: 0.904 ± 0.03	4.225GlnLeu: 4.225 ± 0.075	0.819GlnMet: 0.819 ± 0.025	0.791GlnAsn: 0.791 ± 0.03	1.877GlnPro: 1.877 ± 0.044	2.209GlnGln: 2.209 ± 0.059	3.42GlnArg: 3.42 ± 0.066	2.067GlnSer: 2.067 ± 0.048	1.703GlnThr: 1.703 ± 0.034	3.052GlnVal: 3.052 ± 0.058	0.594GlnTrp: 0.594 ± 0.021	0.727GlnTyr: 0.727 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	6.479ArgAla: 6.479 ± 0.086	0.589ArgCys: 0.589 ± 0.025	4.214ArgAsp: 4.214 ± 0.071	5.08ArgGlu: 5.08 ± 0.089	2.829ArgPhe: 2.829 ± 0.064	4.557ArgGly: 4.557 ± 0.074	2.25ArgHis: 2.25 ± 0.05	3.245ArgIle: 3.245 ± 0.056	1.728ArgLys: 1.728 ± 0.052	9.999ArgLeu: 9.999 ± 0.14	1.642ArgMet: 1.642 ± 0.036	1.571ArgAsn: 1.571 ± 0.033	3.005ArgPro: 3.005 ± 0.057	3.509ArgGln: 3.509 ± 0.062	5.662ArgArg: 5.662 ± 0.083	3.106ArgSer: 3.106 ± 0.049	2.663ArgThr: 2.663 ± 0.053	4.769ArgVal: 4.769 ± 0.069	1.051ArgTrp: 1.051 ± 0.037	2.086ArgTyr: 2.086 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	5.984SerAla: 5.984 ± 0.094	0.485SerCys: 0.485 ± 0.021	3.248SerAsp: 3.248 ± 0.06	3.187SerGlu: 3.187 ± 0.055	1.933SerPhe: 1.933 ± 0.043	5.339SerGly: 5.339 ± 0.088	1.345SerHis: 1.345 ± 0.038	2.47SerIle: 2.47 ± 0.056	1.412SerLys: 1.412 ± 0.04	7.09SerLeu: 7.09 ± 0.086	1.507SerMet: 1.507 ± 0.038	1.417SerAsn: 1.417 ± 0.037	2.963SerPro: 2.963 ± 0.059	2.331SerGln: 2.331 ± 0.056	4.298SerArg: 4.298 ± 0.064	3.351SerSer: 3.351 ± 0.062	2.749SerThr: 2.749 ± 0.056	3.887SerVal: 3.887 ± 0.059	0.734SerTrp: 0.734 ± 0.029	1.277SerTyr: 1.277 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	5.307ThrAla: 5.307 ± 0.081	0.403ThrCys: 0.403 ± 0.019	2.574ThrAsp: 2.574 ± 0.046	2.43ThrGlu: 2.43 ± 0.045	1.698ThrPhe: 1.698 ± 0.042	4.225ThrGly: 4.225 ± 0.069	1.171ThrHis: 1.171 ± 0.029	1.978ThrIle: 1.978 ± 0.045	1.052ThrLys: 1.052 ± 0.034	7.248ThrLeu: 7.248 ± 0.089	0.992ThrMet: 0.992 ± 0.027	1.188ThrAsn: 1.188 ± 0.033	3.462ThrPro: 3.462 ± 0.052	1.928ThrGln: 1.928 ± 0.039	3.471ThrArg: 3.471 ± 0.051	2.766ThrSer: 2.766 ± 0.047	2.7ThrThr: 2.7 ± 0.062	3.31ThrVal: 3.31 ± 0.065	0.66ThrTrp: 0.66 ± 0.028	1.048ThrTyr: 1.048 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	7.929ValAla: 7.929 ± 0.086	0.657ValCys: 0.657 ± 0.025	4.262ValAsp: 4.262 ± 0.066	4.664ValGlu: 4.664 ± 0.075	2.49ValPhe: 2.49 ± 0.054	5.283ValGly: 5.283 ± 0.08	1.446ValHis: 1.446 ± 0.038	3.919ValIle: 3.919 ± 0.066	2.086ValLys: 2.086 ± 0.052	7.57ValLeu: 7.57 ± 0.083	2.038ValMet: 2.038 ± 0.038	1.885ValAsn: 1.885 ± 0.045	3.3ValPro: 3.3 ± 0.057	2.099ValGln: 2.099 ± 0.042	4.228ValArg: 4.228 ± 0.06	4.406ValSer: 4.406 ± 0.074	3.936ValThr: 3.936 ± 0.057	5.571ValVal: 5.571 ± 0.086	0.79ValTrp: 0.79 ± 0.028	1.519ValTyr: 1.519 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	1.139TrpAla: 1.139 ± 0.035	0.186TrpCys: 0.186 ± 0.014	0.556TrpAsp: 0.556 ± 0.026	0.62TrpGlu: 0.62 ± 0.025	0.487TrpPhe: 0.487 ± 0.021	0.924TrpGly: 0.924 ± 0.029	0.426TrpHis: 0.426 ± 0.022	0.612TrpIle: 0.612 ± 0.025	0.373TrpLys: 0.373 ± 0.018	2.392TrpLeu: 2.392 ± 0.053	0.41TrpMet: 0.41 ± 0.021	0.337TrpAsn: 0.337 ± 0.015	0.731TrpPro: 0.731 ± 0.031	1.001TrpGln: 1.001 ± 0.036	1.23TrpArg: 1.23 ± 0.034	0.754TrpSer: 0.754 ± 0.024	0.551TrpThr: 0.551 ± 0.024	0.906TrpVal: 0.906 ± 0.028	0.28TrpTrp: 0.28 ± 0.018	0.323TrpTyr: 0.323 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.331TyrAla: 2.331 ± 0.045	0.252TyrCys: 0.252 ± 0.016	1.316TyrAsp: 1.316 ± 0.041	1.178TyrGlu: 1.178 ± 0.038	0.897TyrPhe: 0.897 ± 0.032	1.947TyrGly: 1.947 ± 0.045	0.633TyrHis: 0.633 ± 0.025	0.875TyrIle: 0.875 ± 0.03	0.523TyrLys: 0.523 ± 0.024	2.855TyrLeu: 2.855 ± 0.057	0.463TyrMet: 0.463 ± 0.021	0.576TyrAsn: 0.576 ± 0.022	1.24TyrPro: 1.24 ± 0.032	1.112TyrGln: 1.112 ± 0.032	2.139TyrArg: 2.139 ± 0.049	1.29TyrSer: 1.29 ± 0.032	1.06TyrThr: 1.06 ± 0.03	1.517TyrVal: 1.517 ± 0.041	0.354TyrTrp: 0.354 ± 0.018	0.706TyrTyr: 0.706 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3429 proteins (1106853 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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