Amino acid dipepetide frequency for Beihai weivirus-like virus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.687AlaAla: 12.687 ± 3.621
0.746AlaCys: 0.746 ± 0.414
3.731AlaAsp: 3.731 ± 0.594
5.97AlaGlu: 5.97 ± 1.982
2.985AlaPhe: 2.985 ± 2.342
7.463AlaGly: 7.463 ± 1.189
3.731AlaHis: 3.731 ± 0.739
7.463AlaIle: 7.463 ± 0.144
5.97AlaLys: 5.97 ± 3.351
8.209AlaLeu: 8.209 ± 3.441
2.985AlaMet: 2.985 ± 0.84
4.478AlaAsn: 4.478 ± 1.513
5.97AlaPro: 5.97 ± 2.017
2.239AlaGln: 2.239 ± 0.09
5.224AlaArg: 5.224 ± 1.099
2.985AlaSer: 2.985 ± 0.324
5.97AlaThr: 5.97 ± 6.017
3.731AlaVal: 3.731 ± 0.594
1.493AlaTrp: 1.493 ± 0.829
0.746AlaTyr: 0.746 ± 0.414
0.0AlaXaa: 0.0 ± 0.0
Cys
1.493CysAla: 1.493 ± 0.829
1.493CysCys: 1.493 ± 0.829
0.746CysAsp: 0.746 ± 0.414
0.746CysGlu: 0.746 ± 0.414
0.746CysPhe: 0.746 ± 0.414
3.731CysGly: 3.731 ± 0.739
0.0CysHis: 0.0 ± 0.0
0.746CysIle: 0.746 ± 0.414
0.0CysLys: 0.0 ± 0.0
2.239CysLeu: 2.239 ± 1.243
0.0CysMet: 0.0 ± 0.0
0.746CysAsn: 0.746 ± 0.414
2.985CysPro: 2.985 ± 1.657
0.746CysGln: 0.746 ± 0.414
0.0CysArg: 0.0 ± 0.0
2.239CysSer: 2.239 ± 0.09
2.239CysThr: 2.239 ± 0.09
0.746CysVal: 0.746 ± 0.414
0.746CysTrp: 0.746 ± 0.414
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.224AspAla: 5.224 ± 3.765
1.493AspCys: 1.493 ± 0.829
2.239AspAsp: 2.239 ± 1.243
1.493AspGlu: 1.493 ± 0.829
0.746AspPhe: 0.746 ± 0.919
3.731AspGly: 3.731 ± 0.739
1.493AspHis: 1.493 ± 0.829
2.239AspIle: 2.239 ± 1.243
3.731AspLys: 3.731 ± 0.739
8.209AspLeu: 8.209 ± 2.108
0.0AspMet: 0.0 ± 0.0
2.239AspAsn: 2.239 ± 0.09
2.985AspPro: 2.985 ± 0.324
1.493AspGln: 1.493 ± 1.837
5.224AspArg: 5.224 ± 1.567
2.985AspSer: 2.985 ± 1.657
2.985AspThr: 2.985 ± 1.657
5.224AspVal: 5.224 ± 1.567
0.746AspTrp: 0.746 ± 0.414
1.493AspTyr: 1.493 ± 0.829
0.0AspXaa: 0.0 ± 0.0
Glu
1.493GluAla: 1.493 ± 0.829
1.493GluCys: 1.493 ± 0.829
4.478GluAsp: 4.478 ± 1.153
5.224GluGlu: 5.224 ± 1.567
2.985GluPhe: 2.985 ± 1.657
3.731GluGly: 3.731 ± 2.072
2.239GluHis: 2.239 ± 1.423
2.985GluIle: 2.985 ± 1.009
1.493GluLys: 1.493 ± 0.829
2.239GluLeu: 2.239 ± 1.243
0.746GluMet: 0.746 ± 0.919
2.985GluAsn: 2.985 ± 0.324
5.224GluPro: 5.224 ± 2.9
0.0GluGln: 0.0 ± 0.0
5.224GluArg: 5.224 ± 1.567
5.97GluSer: 5.97 ± 0.649
2.239GluThr: 2.239 ± 1.243
1.493GluVal: 1.493 ± 0.829
0.0GluTrp: 0.0 ± 0.0
2.239GluTyr: 2.239 ± 0.09
0.0GluXaa: 0.0 ± 0.0
Phe
3.731PheAla: 3.731 ± 0.739
0.0PheCys: 0.0 ± 0.0
1.493PheAsp: 1.493 ± 0.829
3.731PheGlu: 3.731 ± 0.739
1.493PhePhe: 1.493 ± 0.829
2.239PheGly: 2.239 ± 1.423
0.746PheHis: 0.746 ± 0.919
1.493PheIle: 1.493 ± 0.829
4.478PheLys: 4.478 ± 1.153
2.985PheLeu: 2.985 ± 1.009
0.746PheMet: 0.746 ± 0.414
0.746PheAsn: 0.746 ± 0.414
0.746PhePro: 0.746 ± 0.414
0.746PheGln: 0.746 ± 0.414
2.239PheArg: 2.239 ± 0.09
3.731PheSer: 3.731 ± 0.594
3.731PheThr: 3.731 ± 0.739
1.493PheVal: 1.493 ± 0.829
0.0PheTrp: 0.0 ± 0.0
0.746PheTyr: 0.746 ± 0.414
0.0PheXaa: 0.0 ± 0.0
Gly
7.463GlyAla: 7.463 ± 3.855
2.239GlyCys: 2.239 ± 1.243
6.716GlyAsp: 6.716 ± 1.063
3.731GlyGlu: 3.731 ± 0.594
5.224GlyPhe: 5.224 ± 1.567
5.224GlyGly: 5.224 ± 1.099
2.985GlyHis: 2.985 ± 1.657
5.224GlyIle: 5.224 ± 2.432
3.731GlyLys: 3.731 ± 2.072
2.985GlyLeu: 2.985 ± 2.342
1.493GlyMet: 1.493 ± 0.829
2.985GlyAsn: 2.985 ± 0.324
5.224GlyPro: 5.224 ± 3.765
2.985GlyGln: 2.985 ± 0.324
3.731GlyArg: 3.731 ± 0.594
4.478GlySer: 4.478 ± 1.513
2.239GlyThr: 2.239 ± 1.243
8.209GlyVal: 8.209 ± 0.774
0.746GlyTrp: 0.746 ± 0.919
2.985GlyTyr: 2.985 ± 0.324
0.0GlyXaa: 0.0 ± 0.0
His
3.731HisAla: 3.731 ± 0.594
0.746HisCys: 0.746 ± 0.414
2.239HisAsp: 2.239 ± 0.09
0.746HisGlu: 0.746 ± 0.414
0.0HisPhe: 0.0 ± 0.0
3.731HisGly: 3.731 ± 0.739
0.0HisHis: 0.0 ± 0.0
0.746HisIle: 0.746 ± 0.414
0.746HisLys: 0.746 ± 0.414
2.985HisLeu: 2.985 ± 1.657
0.746HisMet: 0.746 ± 0.414
0.746HisAsn: 0.746 ± 0.919
2.239HisPro: 2.239 ± 1.243
0.0HisGln: 0.0 ± 0.0
1.493HisArg: 1.493 ± 0.504
0.746HisSer: 0.746 ± 0.919
0.746HisThr: 0.746 ± 0.414
1.493HisVal: 1.493 ± 0.504
0.746HisTrp: 0.746 ± 0.919
0.746HisTyr: 0.746 ± 0.919
0.0HisXaa: 0.0 ± 0.0
Ile
3.731IleAla: 3.731 ± 0.739
0.0IleCys: 0.0 ± 0.0
1.493IleAsp: 1.493 ± 0.829
3.731IleGlu: 3.731 ± 2.072
2.985IlePhe: 2.985 ± 1.657
3.731IleGly: 3.731 ± 0.739
0.0IleHis: 0.0 ± 0.0
2.985IleIle: 2.985 ± 2.342
2.239IleLys: 2.239 ± 1.243
2.985IleLeu: 2.985 ± 0.324
1.493IleMet: 1.493 ± 0.504
2.985IleAsn: 2.985 ± 1.009
2.239IlePro: 2.239 ± 1.423
3.731IleGln: 3.731 ± 0.594
4.478IleArg: 4.478 ± 0.18
2.985IleSer: 2.985 ± 0.324
3.731IleThr: 3.731 ± 0.594
4.478IleVal: 4.478 ± 0.18
0.746IleTrp: 0.746 ± 0.414
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.731LysAla: 3.731 ± 0.739
1.493LysCys: 1.493 ± 0.504
2.239LysAsp: 2.239 ± 1.243
1.493LysGlu: 1.493 ± 0.829
0.746LysPhe: 0.746 ± 0.414
2.239LysGly: 2.239 ± 0.09
2.985LysHis: 2.985 ± 0.324
2.239LysIle: 2.239 ± 1.243
4.478LysLys: 4.478 ± 2.486
5.224LysLeu: 5.224 ± 0.234
0.746LysMet: 0.746 ± 0.414
2.239LysAsn: 2.239 ± 1.243
2.239LysPro: 2.239 ± 1.243
4.478LysGln: 4.478 ± 1.513
2.985LysArg: 2.985 ± 1.657
1.493LysSer: 1.493 ± 0.829
2.985LysThr: 2.985 ± 1.657
2.985LysVal: 2.985 ± 1.657
1.493LysTrp: 1.493 ± 0.504
0.746LysTyr: 0.746 ± 0.414
0.0LysXaa: 0.0 ± 0.0
Leu
8.209LeuAla: 8.209 ± 3.441
2.239LeuCys: 2.239 ± 1.243
4.478LeuAsp: 4.478 ± 0.18
1.493LeuGlu: 1.493 ± 0.829
3.731LeuPhe: 3.731 ± 0.594
7.463LeuGly: 7.463 ± 0.144
2.985LeuHis: 2.985 ± 1.009
0.746LeuIle: 0.746 ± 0.414
4.478LeuLys: 4.478 ± 1.153
5.97LeuLeu: 5.97 ± 0.684
2.985LeuMet: 2.985 ± 0.823
2.239LeuAsn: 2.239 ± 1.423
4.478LeuPro: 4.478 ± 1.153
4.478LeuGln: 4.478 ± 1.513
4.478LeuArg: 4.478 ± 1.153
5.97LeuSer: 5.97 ± 0.649
2.239LeuThr: 2.239 ± 0.09
1.493LeuVal: 1.493 ± 0.504
0.0LeuTrp: 0.0 ± 0.0
1.493LeuTyr: 1.493 ± 0.829
0.0LeuXaa: 0.0 ± 0.0
Met
3.731MetAla: 3.731 ± 0.594
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.493MetGlu: 1.493 ± 0.504
0.746MetPhe: 0.746 ± 0.414
0.746MetGly: 0.746 ± 0.919
0.0MetHis: 0.0 ± 0.0
1.493MetIle: 1.493 ± 0.504
2.239MetLys: 2.239 ± 1.243
2.985MetLeu: 2.985 ± 0.324
0.0MetMet: 0.0 ± 0.0
0.746MetAsn: 0.746 ± 0.414
4.478MetPro: 4.478 ± 0.18
0.746MetGln: 0.746 ± 0.414
2.985MetArg: 2.985 ± 0.324
0.0MetSer: 0.0 ± 0.0
1.493MetThr: 1.493 ± 0.829
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.746MetTyr: 0.746 ± 0.414
0.0MetXaa: 0.0 ± 0.0
Asn
0.746AsnAla: 0.746 ± 0.919
1.493AsnCys: 1.493 ± 0.504
1.493AsnAsp: 1.493 ± 0.829
2.239AsnGlu: 2.239 ± 1.423
2.239AsnPhe: 2.239 ± 1.243
3.731AsnGly: 3.731 ± 0.739
0.746AsnHis: 0.746 ± 0.919
0.746AsnIle: 0.746 ± 0.919
1.493AsnLys: 1.493 ± 0.504
2.239AsnLeu: 2.239 ± 0.09
1.493AsnMet: 1.493 ± 0.504
0.0AsnAsn: 0.0 ± 0.0
2.239AsnPro: 2.239 ± 1.423
1.493AsnGln: 1.493 ± 0.504
1.493AsnArg: 1.493 ± 0.504
0.0AsnSer: 0.0 ± 0.0
2.985AsnThr: 2.985 ± 0.324
5.97AsnVal: 5.97 ± 0.684
1.493AsnTrp: 1.493 ± 0.504
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.731ProAla: 3.731 ± 3.26
0.746ProCys: 0.746 ± 0.414
4.478ProAsp: 4.478 ± 0.18
5.97ProGlu: 5.97 ± 1.982
1.493ProPhe: 1.493 ± 0.829
7.463ProGly: 7.463 ± 0.144
0.0ProHis: 0.0 ± 0.0
1.493ProIle: 1.493 ± 1.837
3.731ProLys: 3.731 ± 2.072
1.493ProLeu: 1.493 ± 0.504
0.746ProMet: 0.746 ± 0.414
0.746ProAsn: 0.746 ± 0.414
3.731ProPro: 3.731 ± 0.594
1.493ProGln: 1.493 ± 0.504
6.716ProArg: 6.716 ± 1.603
3.731ProSer: 3.731 ± 0.594
5.97ProThr: 5.97 ± 0.684
5.224ProVal: 5.224 ± 0.234
2.239ProTrp: 2.239 ± 0.09
1.493ProTyr: 1.493 ± 0.504
0.0ProXaa: 0.0 ± 0.0
Gln
3.731GlnAla: 3.731 ± 3.26
0.746GlnCys: 0.746 ± 0.414
2.239GlnAsp: 2.239 ± 0.09
0.0GlnGlu: 0.0 ± 0.0
0.746GlnPhe: 0.746 ± 0.919
2.239GlnGly: 2.239 ± 1.423
0.746GlnHis: 0.746 ± 0.414
2.985GlnIle: 2.985 ± 1.009
0.746GlnLys: 0.746 ± 0.414
2.239GlnLeu: 2.239 ± 0.09
0.746GlnMet: 0.746 ± 0.414
1.493GlnAsn: 1.493 ± 1.837
2.239GlnPro: 2.239 ± 1.243
0.746GlnGln: 0.746 ± 0.919
2.985GlnArg: 2.985 ± 0.324
5.224GlnSer: 5.224 ± 1.567
1.493GlnThr: 1.493 ± 0.504
2.985GlnVal: 2.985 ± 1.009
0.746GlnTrp: 0.746 ± 0.414
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
11.94ArgAla: 11.94 ± 0.036
2.239ArgCys: 2.239 ± 0.09
4.478ArgAsp: 4.478 ± 1.153
2.239ArgGlu: 2.239 ± 1.243
2.985ArgPhe: 2.985 ± 0.324
5.224ArgGly: 5.224 ± 5.098
1.493ArgHis: 1.493 ± 0.829
2.985ArgIle: 2.985 ± 1.657
2.239ArgLys: 2.239 ± 0.09
2.985ArgLeu: 2.985 ± 1.657
1.493ArgMet: 1.493 ± 0.829
2.985ArgAsn: 2.985 ± 2.342
1.493ArgPro: 1.493 ± 0.829
1.493ArgGln: 1.493 ± 0.829
2.985ArgArg: 2.985 ± 0.324
2.985ArgSer: 2.985 ± 1.009
5.224ArgThr: 5.224 ± 1.099
4.478ArgVal: 4.478 ± 1.513
1.493ArgTrp: 1.493 ± 0.829
2.239ArgTyr: 2.239 ± 1.243
0.0ArgXaa: 0.0 ± 0.0
Ser
5.97SerAla: 5.97 ± 1.982
1.493SerCys: 1.493 ± 0.829
1.493SerAsp: 1.493 ± 0.504
0.746SerGlu: 0.746 ± 0.414
0.746SerPhe: 0.746 ± 0.919
2.985SerGly: 2.985 ± 1.009
0.746SerHis: 0.746 ± 0.414
4.478SerIle: 4.478 ± 1.153
2.985SerLys: 2.985 ± 1.657
5.97SerLeu: 5.97 ± 0.649
3.731SerMet: 3.731 ± 0.594
2.239SerAsn: 2.239 ± 0.09
2.239SerPro: 2.239 ± 1.423
0.746SerGln: 0.746 ± 0.414
4.478SerArg: 4.478 ± 1.153
2.985SerSer: 2.985 ± 1.009
3.731SerThr: 3.731 ± 0.739
8.209SerVal: 8.209 ± 3.441
1.493SerTrp: 1.493 ± 0.829
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.478ThrAla: 4.478 ± 2.846
2.985ThrCys: 2.985 ± 1.657
2.985ThrAsp: 2.985 ± 1.009
4.478ThrGlu: 4.478 ± 2.486
2.239ThrPhe: 2.239 ± 0.09
5.224ThrGly: 5.224 ± 1.567
1.493ThrHis: 1.493 ± 0.504
3.731ThrIle: 3.731 ± 2.072
2.985ThrLys: 2.985 ± 1.657
2.985ThrLeu: 2.985 ± 0.324
0.746ThrMet: 0.746 ± 0.414
1.493ThrAsn: 1.493 ± 0.504
6.716ThrPro: 6.716 ± 1.603
5.224ThrGln: 5.224 ± 1.099
2.985ThrArg: 2.985 ± 3.675
2.239ThrSer: 2.239 ± 0.09
7.463ThrThr: 7.463 ± 3.855
2.239ThrVal: 2.239 ± 0.09
0.746ThrTrp: 0.746 ± 0.414
4.478ThrTyr: 4.478 ± 1.513
0.0ThrXaa: 0.0 ± 0.0
Val
4.478ValAla: 4.478 ± 0.18
0.746ValCys: 0.746 ± 0.414
5.224ValAsp: 5.224 ± 0.234
4.478ValGlu: 4.478 ± 0.18
2.239ValPhe: 2.239 ± 1.243
7.463ValGly: 7.463 ± 2.522
1.493ValHis: 1.493 ± 0.504
2.985ValIle: 2.985 ± 1.657
1.493ValLys: 1.493 ± 0.829
5.224ValLeu: 5.224 ± 0.234
1.493ValMet: 1.493 ± 0.504
2.239ValAsn: 2.239 ± 0.09
2.985ValPro: 2.985 ± 2.342
2.239ValGln: 2.239 ± 0.09
3.731ValArg: 3.731 ± 0.594
5.224ValSer: 5.224 ± 0.234
5.97ValThr: 5.97 ± 2.017
4.478ValVal: 4.478 ± 1.513
0.746ValTrp: 0.746 ± 0.414
2.985ValTyr: 2.985 ± 0.324
0.0ValXaa: 0.0 ± 0.0
Trp
2.239TrpAla: 2.239 ± 1.423
0.0TrpCys: 0.0 ± 0.0
2.239TrpAsp: 2.239 ± 0.09
2.239TrpGlu: 2.239 ± 1.243
0.0TrpPhe: 0.0 ± 0.0
0.746TrpGly: 0.746 ± 0.919
0.746TrpHis: 0.746 ± 0.414
2.985TrpIle: 2.985 ± 0.324
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
1.493TrpMet: 1.493 ± 0.829
0.0TrpAsn: 0.0 ± 0.0
1.493TrpPro: 1.493 ± 0.829
0.0TrpGln: 0.0 ± 0.0
0.746TrpArg: 0.746 ± 0.414
0.0TrpSer: 0.0 ± 0.0
0.746TrpThr: 0.746 ± 0.414
0.0TrpVal: 0.0 ± 0.0
1.493TrpTrp: 1.493 ± 0.829
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.985TyrAla: 2.985 ± 0.324
0.0TyrCys: 0.0 ± 0.0
1.493TyrAsp: 1.493 ± 0.504
2.239TyrGlu: 2.239 ± 0.09
2.239TyrPhe: 2.239 ± 0.09
1.493TyrGly: 1.493 ± 0.829
0.746TyrHis: 0.746 ± 0.414
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
1.493TyrLeu: 1.493 ± 0.829
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
0.746TyrPro: 0.746 ± 0.919
0.0TyrGln: 0.0 ± 0.0
1.493TyrArg: 1.493 ± 0.829
1.493TyrSer: 1.493 ± 0.829
3.731TyrThr: 3.731 ± 0.594
2.985TyrVal: 2.985 ± 0.324
0.0TyrTrp: 0.0 ± 0.0
1.493TyrTyr: 1.493 ± 0.504
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1341 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski