Amino acid dipepetide frequency for Phaeocystidibacter luteus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.343AlaAla: 5.343 ± 0.092
0.609AlaCys: 0.609 ± 0.027
4.24AlaAsp: 4.24 ± 0.077
5.058AlaGlu: 5.058 ± 0.075
3.651AlaPhe: 3.651 ± 0.056
5.364AlaGly: 5.364 ± 0.091
1.315AlaHis: 1.315 ± 0.043
5.053AlaIle: 5.053 ± 0.082
3.629AlaLys: 3.629 ± 0.075
7.099AlaLeu: 7.099 ± 0.114
1.998AlaMet: 1.998 ± 0.051
3.37AlaAsn: 3.37 ± 0.075
2.47AlaPro: 2.47 ± 0.054
2.962AlaGln: 2.962 ± 0.056
3.172AlaArg: 3.172 ± 0.058
4.879AlaSer: 4.879 ± 0.102
3.96AlaThr: 3.96 ± 0.105
4.992AlaVal: 4.992 ± 0.083
1.0AlaTrp: 1.0 ± 0.034
2.667AlaTyr: 2.667 ± 0.053
0.0AlaXaa: 0.0 ± 0.0
Cys
0.536CysAla: 0.536 ± 0.027
0.074CysCys: 0.074 ± 0.009
0.507CysAsp: 0.507 ± 0.024
0.461CysGlu: 0.461 ± 0.021
0.334CysPhe: 0.334 ± 0.031
0.678CysGly: 0.678 ± 0.033
0.208CysHis: 0.208 ± 0.016
0.447CysIle: 0.447 ± 0.023
0.284CysLys: 0.284 ± 0.018
0.543CysLeu: 0.543 ± 0.024
0.147CysMet: 0.147 ± 0.012
0.357CysAsn: 0.357 ± 0.022
0.357CysPro: 0.357 ± 0.021
0.202CysGln: 0.202 ± 0.016
0.259CysArg: 0.259 ± 0.016
0.556CysSer: 0.556 ± 0.025
0.459CysThr: 0.459 ± 0.026
0.457CysVal: 0.457 ± 0.023
0.1CysTrp: 0.1 ± 0.012
0.252CysTyr: 0.252 ± 0.018
0.0CysXaa: 0.0 ± 0.0
Asp
4.287AspAla: 4.287 ± 0.088
0.426AspCys: 0.426 ± 0.025
3.215AspAsp: 3.215 ± 0.062
4.304AspGlu: 4.304 ± 0.074
3.135AspPhe: 3.135 ± 0.062
4.494AspGly: 4.494 ± 0.07
1.125AspHis: 1.125 ± 0.035
3.934AspIle: 3.934 ± 0.071
2.655AspLys: 2.655 ± 0.064
5.483AspLeu: 5.483 ± 0.076
1.44AspMet: 1.44 ± 0.039
2.5AspAsn: 2.5 ± 0.071
2.456AspPro: 2.456 ± 0.06
1.847AspGln: 1.847 ± 0.047
2.798AspArg: 2.798 ± 0.058
4.302AspSer: 4.302 ± 0.101
3.25AspThr: 3.25 ± 0.091
4.289AspVal: 4.289 ± 0.071
0.936AspTrp: 0.936 ± 0.028
2.452AspTyr: 2.452 ± 0.053
0.0AspXaa: 0.0 ± 0.0
Glu
5.269GluAla: 5.269 ± 0.098
0.382GluCys: 0.382 ± 0.022
3.975GluAsp: 3.975 ± 0.069
5.614GluGlu: 5.614 ± 0.103
3.017GluPhe: 3.017 ± 0.056
4.576GluGly: 4.576 ± 0.081
1.36GluHis: 1.36 ± 0.039
4.637GluIle: 4.637 ± 0.079
3.85GluLys: 3.85 ± 0.084
6.543GluLeu: 6.543 ± 0.092
2.001GluMet: 2.001 ± 0.049
3.381GluAsn: 3.381 ± 0.064
2.023GluPro: 2.023 ± 0.047
2.227GluGln: 2.227 ± 0.054
3.641GluArg: 3.641 ± 0.07
4.064GluSer: 4.064 ± 0.073
3.35GluThr: 3.35 ± 0.062
5.3GluVal: 5.3 ± 0.089
1.025GluTrp: 1.025 ± 0.036
2.656GluTyr: 2.656 ± 0.057
0.0GluXaa: 0.0 ± 0.0
Phe
3.506PheAla: 3.506 ± 0.062
0.327PheCys: 0.327 ± 0.019
3.228PheAsp: 3.228 ± 0.066
3.366PheGlu: 3.366 ± 0.065
2.174PhePhe: 2.174 ± 0.06
3.876PheGly: 3.876 ± 0.067
0.863PheHis: 0.863 ± 0.033
3.104PheIle: 3.104 ± 0.061
2.175PheLys: 2.175 ± 0.054
3.906PheLeu: 3.906 ± 0.085
1.124PheMet: 1.124 ± 0.034
2.431PheAsn: 2.431 ± 0.052
1.68PhePro: 1.68 ± 0.044
1.554PheGln: 1.554 ± 0.044
2.121PheArg: 2.121 ± 0.055
3.494PheSer: 3.494 ± 0.073
3.092PheThr: 3.092 ± 0.06
3.151PheVal: 3.151 ± 0.065
0.648PheTrp: 0.648 ± 0.029
1.895PheTyr: 1.895 ± 0.045
0.0PheXaa: 0.0 ± 0.0
Gly
5.013GlyAla: 5.013 ± 0.082
0.677GlyCys: 0.677 ± 0.052
4.21GlyAsp: 4.21 ± 0.072
4.589GlyGlu: 4.589 ± 0.081
3.551GlyPhe: 3.551 ± 0.066
5.754GlyGly: 5.754 ± 0.117
1.383GlyHis: 1.383 ± 0.04
4.976GlyIle: 4.976 ± 0.073
3.748GlyLys: 3.748 ± 0.089
6.407GlyLeu: 6.407 ± 0.092
2.117GlyMet: 2.117 ± 0.046
3.445GlyAsn: 3.445 ± 0.078
1.994GlyPro: 1.994 ± 0.064
2.57GlyGln: 2.57 ± 0.059
3.232GlyArg: 3.232 ± 0.059
4.93GlySer: 4.93 ± 0.105
4.766GlyThr: 4.766 ± 0.119
5.412GlyVal: 5.412 ± 0.065
1.197GlyTrp: 1.197 ± 0.039
3.066GlyTyr: 3.066 ± 0.068
0.0GlyXaa: 0.0 ± 0.0
His
1.333HisAla: 1.333 ± 0.043
0.178HisCys: 0.178 ± 0.015
1.061HisAsp: 1.061 ± 0.03
1.249HisGlu: 1.249 ± 0.034
1.178HisPhe: 1.178 ± 0.038
1.307HisGly: 1.307 ± 0.036
0.572HisHis: 0.572 ± 0.025
1.352HisIle: 1.352 ± 0.038
0.902HisLys: 0.902 ± 0.032
2.032HisLeu: 2.032 ± 0.052
0.46HisMet: 0.46 ± 0.023
0.845HisAsn: 0.845 ± 0.03
1.139HisPro: 1.139 ± 0.035
0.692HisGln: 0.692 ± 0.027
1.025HisArg: 1.025 ± 0.033
1.206HisSer: 1.206 ± 0.036
1.077HisThr: 1.077 ± 0.043
1.275HisVal: 1.275 ± 0.031
0.326HisTrp: 0.326 ± 0.019
0.917HisTyr: 0.917 ± 0.031
0.0HisXaa: 0.0 ± 0.0
Ile
5.243IleAla: 5.243 ± 0.074
0.483IleCys: 0.483 ± 0.025
4.539IleAsp: 4.539 ± 0.07
4.933IleGlu: 4.933 ± 0.085
2.749IlePhe: 2.749 ± 0.055
4.737IleGly: 4.737 ± 0.084
1.522IleHis: 1.522 ± 0.039
3.799IleIle: 3.799 ± 0.078
2.563IleLys: 2.563 ± 0.061
5.994IleLeu: 5.994 ± 0.105
1.215IleMet: 1.215 ± 0.042
2.895IleAsn: 2.895 ± 0.057
3.047IlePro: 3.047 ± 0.054
2.514IleGln: 2.514 ± 0.049
3.348IleArg: 3.348 ± 0.062
4.593IleSer: 4.593 ± 0.068
3.904IleThr: 3.904 ± 0.081
4.292IleVal: 4.292 ± 0.069
0.755IleTrp: 0.755 ± 0.027
2.294IleTyr: 2.294 ± 0.055
0.0IleXaa: 0.0 ± 0.0
Lys
3.914LysAla: 3.914 ± 0.085
0.286LysCys: 0.286 ± 0.018
2.649LysAsp: 2.649 ± 0.065
3.493LysGlu: 3.493 ± 0.074
1.978LysPhe: 1.978 ± 0.049
3.27LysGly: 3.27 ± 0.072
1.086LysHis: 1.086 ± 0.035
2.895LysIle: 2.895 ± 0.065
3.132LysLys: 3.132 ± 0.079
4.476LysLeu: 4.476 ± 0.089
1.441LysMet: 1.441 ± 0.042
2.206LysAsn: 2.206 ± 0.051
1.885LysPro: 1.885 ± 0.053
1.487LysGln: 1.487 ± 0.043
2.762LysArg: 2.762 ± 0.061
3.413LysSer: 3.413 ± 0.072
2.539LysThr: 2.539 ± 0.059
3.632LysVal: 3.632 ± 0.066
0.795LysTrp: 0.795 ± 0.033
1.975LysTyr: 1.975 ± 0.05
0.0LysXaa: 0.0 ± 0.0
Leu
6.609LeuAla: 6.609 ± 0.097
0.615LeuCys: 0.615 ± 0.023
5.354LeuAsp: 5.354 ± 0.086
6.206LeuGlu: 6.206 ± 0.099
4.245LeuPhe: 4.245 ± 0.086
6.231LeuGly: 6.231 ± 0.092
1.964LeuHis: 1.964 ± 0.051
5.896LeuIle: 5.896 ± 0.106
4.888LeuLys: 4.888 ± 0.093
8.467LeuLeu: 8.467 ± 0.14
2.218LeuMet: 2.218 ± 0.051
4.762LeuAsn: 4.762 ± 0.08
3.918LeuPro: 3.918 ± 0.065
3.062LeuGln: 3.062 ± 0.057
4.47LeuArg: 4.47 ± 0.074
7.011LeuSer: 7.011 ± 0.088
5.116LeuThr: 5.116 ± 0.074
5.676LeuVal: 5.676 ± 0.083
1.094LeuTrp: 1.094 ± 0.033
3.147LeuTyr: 3.147 ± 0.062
0.0LeuXaa: 0.0 ± 0.0
Met
1.877MetAla: 1.877 ± 0.043
0.13MetCys: 0.13 ± 0.012
1.548MetAsp: 1.548 ± 0.037
1.682MetGlu: 1.682 ± 0.042
0.857MetPhe: 0.857 ± 0.03
1.782MetGly: 1.782 ± 0.036
0.506MetHis: 0.506 ± 0.021
1.458MetIle: 1.458 ± 0.045
1.955MetLys: 1.955 ± 0.043
2.12MetLeu: 2.12 ± 0.052
0.75MetMet: 0.75 ± 0.03
1.426MetAsn: 1.426 ± 0.039
1.017MetPro: 1.017 ± 0.033
0.775MetGln: 0.775 ± 0.028
1.476MetArg: 1.476 ± 0.038
1.833MetSer: 1.833 ± 0.041
1.436MetThr: 1.436 ± 0.039
1.521MetVal: 1.521 ± 0.041
0.243MetTrp: 0.243 ± 0.017
0.787MetTyr: 0.787 ± 0.028
0.0MetXaa: 0.0 ± 0.0
Asn
3.576AsnAla: 3.576 ± 0.071
0.398AsnCys: 0.398 ± 0.029
2.789AsnAsp: 2.789 ± 0.062
2.918AsnGlu: 2.918 ± 0.05
2.192AsnPhe: 2.192 ± 0.053
4.259AsnGly: 4.259 ± 0.124
1.015AsnHis: 1.015 ± 0.031
2.949AsnIle: 2.949 ± 0.058
1.9AsnLys: 1.9 ± 0.057
4.27AsnLeu: 4.27 ± 0.075
1.045AsnMet: 1.045 ± 0.029
2.19AsnAsn: 2.19 ± 0.061
2.89AsnPro: 2.89 ± 0.06
1.781AsnGln: 1.781 ± 0.045
2.408AsnArg: 2.408 ± 0.05
3.273AsnSer: 3.273 ± 0.066
2.72AsnThr: 2.72 ± 0.063
3.315AsnVal: 3.315 ± 0.071
0.784AsnTrp: 0.784 ± 0.031
1.886AsnTyr: 1.886 ± 0.045
0.0AsnXaa: 0.0 ± 0.0
Pro
2.738ProAla: 2.738 ± 0.058
0.279ProCys: 0.279 ± 0.02
2.552ProAsp: 2.552 ± 0.054
3.241ProGlu: 3.241 ± 0.06
1.905ProPhe: 1.905 ± 0.047
2.71ProGly: 2.71 ± 0.057
0.829ProHis: 0.829 ± 0.031
2.547ProIle: 2.547 ± 0.05
1.884ProLys: 1.884 ± 0.047
3.134ProLeu: 3.134 ± 0.062
0.994ProMet: 0.994 ± 0.033
2.324ProAsn: 2.324 ± 0.059
1.15ProPro: 1.15 ± 0.05
1.343ProGln: 1.343 ± 0.035
1.343ProArg: 1.343 ± 0.039
2.86ProSer: 2.86 ± 0.065
2.402ProThr: 2.402 ± 0.062
2.787ProVal: 2.787 ± 0.06
0.52ProTrp: 0.52 ± 0.025
1.559ProTyr: 1.559 ± 0.053
0.0ProXaa: 0.0 ± 0.0
Gln
2.405GlnAla: 2.405 ± 0.046
0.18GlnCys: 0.18 ± 0.015
1.733GlnAsp: 1.733 ± 0.043
2.206GlnGlu: 2.206 ± 0.057
1.766GlnPhe: 1.766 ± 0.043
2.057GlnGly: 2.057 ± 0.057
0.678GlnHis: 0.678 ± 0.028
2.293GlnIle: 2.293 ± 0.056
1.719GlnLys: 1.719 ± 0.05
3.349GlnLeu: 3.349 ± 0.059
0.985GlnMet: 0.985 ± 0.032
1.755GlnAsn: 1.755 ± 0.046
1.383GlnPro: 1.383 ± 0.043
1.314GlnGln: 1.314 ± 0.041
1.818GlnArg: 1.818 ± 0.043
2.376GlnSer: 2.376 ± 0.058
1.919GlnThr: 1.919 ± 0.048
2.523GlnVal: 2.523 ± 0.049
0.515GlnTrp: 0.515 ± 0.027
1.31GlnTyr: 1.31 ± 0.045
0.0GlnXaa: 0.0 ± 0.0
Arg
3.119ArgAla: 3.119 ± 0.058
0.264ArgCys: 0.264 ± 0.016
2.572ArgAsp: 2.572 ± 0.058
3.397ArgGlu: 3.397 ± 0.061
2.523ArgPhe: 2.523 ± 0.06
2.983ArgGly: 2.983 ± 0.051
0.869ArgHis: 0.869 ± 0.029
3.741ArgIle: 3.741 ± 0.067
2.816ArgLys: 2.816 ± 0.058
4.321ArgLeu: 4.321 ± 0.077
1.46ArgMet: 1.46 ± 0.04
2.303ArgAsn: 2.303 ± 0.055
1.763ArgPro: 1.763 ± 0.046
1.62ArgGln: 1.62 ± 0.05
2.436ArgArg: 2.436 ± 0.043
2.981ArgSer: 2.981 ± 0.063
2.523ArgThr: 2.523 ± 0.046
3.327ArgVal: 3.327 ± 0.056
0.744ArgTrp: 0.744 ± 0.032
1.954ArgTyr: 1.954 ± 0.048
0.0ArgXaa: 0.0 ± 0.0
Ser
5.328SerAla: 5.328 ± 0.097
0.644SerCys: 0.644 ± 0.036
4.044SerAsp: 4.044 ± 0.065
4.441SerGlu: 4.441 ± 0.085
3.721SerPhe: 3.721 ± 0.078
5.676SerGly: 5.676 ± 0.109
1.216SerHis: 1.216 ± 0.038
4.795SerIle: 4.795 ± 0.073
3.117SerLys: 3.117 ± 0.067
6.256SerLeu: 6.256 ± 0.09
1.733SerMet: 1.733 ± 0.044
3.479SerAsn: 3.479 ± 0.07
2.557SerPro: 2.557 ± 0.053
2.19SerGln: 2.19 ± 0.048
2.835SerArg: 2.835 ± 0.059
5.218SerSer: 5.218 ± 0.106
4.458SerThr: 4.458 ± 0.091
4.538SerVal: 4.538 ± 0.078
1.004SerTrp: 1.004 ± 0.045
2.584SerTyr: 2.584 ± 0.059
0.0SerXaa: 0.0 ± 0.0
Thr
4.319ThrAla: 4.319 ± 0.107
0.392ThrCys: 0.392 ± 0.023
3.355ThrAsp: 3.355 ± 0.097
3.459ThrGlu: 3.459 ± 0.058
2.831ThrPhe: 2.831 ± 0.057
4.714ThrGly: 4.714 ± 0.102
1.08ThrHis: 1.08 ± 0.033
3.891ThrIle: 3.891 ± 0.083
2.258ThrLys: 2.258 ± 0.055
5.463ThrLeu: 5.463 ± 0.078
1.125ThrMet: 1.125 ± 0.037
2.622ThrAsn: 2.622 ± 0.076
2.712ThrPro: 2.712 ± 0.076
1.806ThrGln: 1.806 ± 0.047
2.312ThrArg: 2.312 ± 0.057
4.209ThrSer: 4.209 ± 0.094
3.692ThrThr: 3.692 ± 0.106
4.298ThrVal: 4.298 ± 0.117
0.901ThrTrp: 0.901 ± 0.038
2.464ThrTyr: 2.464 ± 0.07
0.0ThrXaa: 0.0 ± 0.0
Val
4.812ValAla: 4.812 ± 0.074
0.478ValCys: 0.478 ± 0.022
4.485ValAsp: 4.485 ± 0.077
5.061ValGlu: 5.061 ± 0.086
3.167ValPhe: 3.167 ± 0.06
4.773ValGly: 4.773 ± 0.078
1.369ValHis: 1.369 ± 0.037
4.497ValIle: 4.497 ± 0.074
3.35ValLys: 3.35 ± 0.065
6.403ValLeu: 6.403 ± 0.1
1.588ValMet: 1.588 ± 0.039
3.471ValAsn: 3.471 ± 0.067
2.635ValPro: 2.635 ± 0.055
2.385ValGln: 2.385 ± 0.05
3.386ValArg: 3.386 ± 0.066
4.836ValSer: 4.836 ± 0.069
3.919ValThr: 3.919 ± 0.128
5.348ValVal: 5.348 ± 0.094
0.832ValTrp: 0.832 ± 0.031
2.733ValTyr: 2.733 ± 0.061
0.0ValXaa: 0.0 ± 0.0
Trp
0.882TrpAla: 0.882 ± 0.033
0.11TrpCys: 0.11 ± 0.012
0.88TrpAsp: 0.88 ± 0.037
0.891TrpGlu: 0.891 ± 0.033
0.612TrpPhe: 0.612 ± 0.029
0.962TrpGly: 0.962 ± 0.038
0.286TrpHis: 0.286 ± 0.019
0.909TrpIle: 0.909 ± 0.028
0.882TrpLys: 0.882 ± 0.034
1.238TrpLeu: 1.238 ± 0.041
0.495TrpMet: 0.495 ± 0.023
0.826TrpAsn: 0.826 ± 0.029
0.398TrpPro: 0.398 ± 0.022
0.462TrpGln: 0.462 ± 0.022
0.651TrpArg: 0.651 ± 0.032
1.048TrpSer: 1.048 ± 0.05
0.915TrpThr: 0.915 ± 0.038
0.965TrpVal: 0.965 ± 0.035
0.227TrpTrp: 0.227 ± 0.016
0.548TrpTyr: 0.548 ± 0.025
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.721TyrAla: 2.721 ± 0.057
0.286TyrCys: 0.286 ± 0.018
2.389TyrAsp: 2.389 ± 0.053
2.32TyrGlu: 2.32 ± 0.05
2.131TyrPhe: 2.131 ± 0.051
2.835TyrGly: 2.835 ± 0.053
0.881TyrHis: 0.881 ± 0.034
2.247TyrIle: 2.247 ± 0.051
1.608TyrLys: 1.608 ± 0.044
3.445TyrLeu: 3.445 ± 0.056
0.84TyrMet: 0.84 ± 0.029
1.969TyrAsn: 1.969 ± 0.05
1.626TyrPro: 1.626 ± 0.041
1.49TyrGln: 1.49 ± 0.039
2.226TyrArg: 2.226 ± 0.064
2.751TyrSer: 2.751 ± 0.057
2.407TyrThr: 2.407 ± 0.077
2.43TyrVal: 2.43 ± 0.051
0.542TyrTrp: 0.542 ± 0.024
1.735TyrTyr: 1.735 ± 0.051
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2801 proteins (972285 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski