Amino acid dipepetide frequency for Atopobium minutum 10063974

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.898AlaAla: 11.898 ± 0.225
1.735AlaCys: 1.735 ± 0.06
5.862AlaAsp: 5.862 ± 0.128
5.33AlaGlu: 5.33 ± 0.127
3.552AlaPhe: 3.552 ± 0.088
7.378AlaGly: 7.378 ± 0.131
2.515AlaHis: 2.515 ± 0.083
5.774AlaIle: 5.774 ± 0.121
4.681AlaLys: 4.681 ± 0.108
11.069AlaLeu: 11.069 ± 0.186
2.539AlaMet: 2.539 ± 0.074
3.216AlaAsn: 3.216 ± 0.089
3.415AlaPro: 3.415 ± 0.105
5.935AlaGln: 5.935 ± 0.133
5.16AlaArg: 5.16 ± 0.108
6.529AlaSer: 6.529 ± 0.139
5.704AlaThr: 5.704 ± 0.115
7.036AlaVal: 7.036 ± 0.126
1.07AlaTrp: 1.07 ± 0.052
2.946AlaTyr: 2.946 ± 0.081
0.0AlaXaa: 0.0 ± 0.0
Cys
1.526CysAla: 1.526 ± 0.069
0.217CysCys: 0.217 ± 0.023
1.019CysAsp: 1.019 ± 0.049
0.837CysGlu: 0.837 ± 0.047
0.473CysPhe: 0.473 ± 0.028
1.451CysGly: 1.451 ± 0.059
0.301CysHis: 0.301 ± 0.023
0.9CysIle: 0.9 ± 0.046
0.583CysLys: 0.583 ± 0.035
1.08CysLeu: 1.08 ± 0.043
0.321CysMet: 0.321 ± 0.029
0.46CysAsn: 0.46 ± 0.032
0.671CysPro: 0.671 ± 0.037
0.385CysGln: 0.385 ± 0.029
0.559CysArg: 0.559 ± 0.033
0.863CysSer: 0.863 ± 0.041
0.827CysThr: 0.827 ± 0.04
1.271CysVal: 1.271 ± 0.053
0.133CysTrp: 0.133 ± 0.018
0.372CysTyr: 0.372 ± 0.03
0.0CysXaa: 0.0 ± 0.0
Asp
6.537AspAla: 6.537 ± 0.134
0.767AspCys: 0.767 ± 0.041
3.312AspAsp: 3.312 ± 0.11
4.716AspGlu: 4.716 ± 0.108
2.51AspPhe: 2.51 ± 0.073
4.548AspGly: 4.548 ± 0.107
1.09AspHis: 1.09 ± 0.049
3.531AspIle: 3.531 ± 0.093
3.092AspLys: 3.092 ± 0.083
5.228AspLeu: 5.228 ± 0.12
1.586AspMet: 1.586 ± 0.048
1.931AspAsn: 1.931 ± 0.076
2.699AspPro: 2.699 ± 0.081
1.786AspGln: 1.786 ± 0.06
2.484AspArg: 2.484 ± 0.076
3.224AspSer: 3.224 ± 0.088
3.615AspThr: 3.615 ± 0.091
4.62AspVal: 4.62 ± 0.092
0.679AspTrp: 0.679 ± 0.04
1.935AspTyr: 1.935 ± 0.065
0.0AspXaa: 0.0 ± 0.0
Glu
6.081GluAla: 6.081 ± 0.132
0.618GluCys: 0.618 ± 0.039
3.343GluAsp: 3.343 ± 0.096
3.9GluGlu: 3.9 ± 0.12
2.087GluPhe: 2.087 ± 0.062
3.846GluGly: 3.846 ± 0.092
1.555GluHis: 1.555 ± 0.06
3.208GluIle: 3.208 ± 0.091
3.468GluLys: 3.468 ± 0.093
6.846GluLeu: 6.846 ± 0.131
1.477GluMet: 1.477 ± 0.052
2.034GluAsn: 2.034 ± 0.069
2.023GluPro: 2.023 ± 0.071
3.292GluGln: 3.292 ± 0.084
3.452GluArg: 3.452 ± 0.1
2.862GluSer: 2.862 ± 0.076
2.682GluThr: 2.682 ± 0.078
4.29GluVal: 4.29 ± 0.111
0.595GluTrp: 0.595 ± 0.035
1.721GluTyr: 1.721 ± 0.057
0.0GluXaa: 0.0 ± 0.0
Phe
3.574PheAla: 3.574 ± 0.087
0.565PheCys: 0.565 ± 0.033
2.693PheAsp: 2.693 ± 0.071
2.418PheGlu: 2.418 ± 0.073
1.422PhePhe: 1.422 ± 0.061
3.208PheGly: 3.208 ± 0.092
0.644PheHis: 0.644 ± 0.04
2.424PheIle: 2.424 ± 0.083
1.596PheLys: 1.596 ± 0.057
2.995PheLeu: 2.995 ± 0.086
0.978PheMet: 0.978 ± 0.051
1.262PheAsn: 1.262 ± 0.056
1.166PhePro: 1.166 ± 0.045
0.827PheGln: 0.827 ± 0.038
1.254PheArg: 1.254 ± 0.046
2.801PheSer: 2.801 ± 0.069
2.208PheThr: 2.208 ± 0.06
3.112PheVal: 3.112 ± 0.083
0.403PheTrp: 0.403 ± 0.028
1.176PheTyr: 1.176 ± 0.05
0.0PheXaa: 0.0 ± 0.0
Gly
6.621GlyAla: 6.621 ± 0.131
1.164GlyCys: 1.164 ± 0.051
3.759GlyAsp: 3.759 ± 0.092
3.624GlyGlu: 3.624 ± 0.093
3.126GlyPhe: 3.126 ± 0.089
5.037GlyGly: 5.037 ± 0.129
1.549GlyHis: 1.549 ± 0.055
5.17GlyIle: 5.17 ± 0.123
4.247GlyLys: 4.247 ± 0.102
6.24GlyLeu: 6.24 ± 0.111
2.361GlyMet: 2.361 ± 0.072
2.324GlyAsn: 2.324 ± 0.076
1.856GlyPro: 1.856 ± 0.068
2.355GlyGln: 2.355 ± 0.078
3.335GlyArg: 3.335 ± 0.091
4.798GlySer: 4.798 ± 0.106
4.771GlyThr: 4.771 ± 0.111
5.649GlyVal: 5.649 ± 0.114
1.011GlyTrp: 1.011 ± 0.068
2.47GlyTyr: 2.47 ± 0.081
0.0GlyXaa: 0.0 ± 0.0
His
2.224HisAla: 2.224 ± 0.072
0.311HisCys: 0.311 ± 0.027
1.367HisAsp: 1.367 ± 0.052
1.444HisGlu: 1.444 ± 0.068
0.759HisPhe: 0.759 ± 0.035
1.606HisGly: 1.606 ± 0.057
0.44HisHis: 0.44 ± 0.029
1.365HisIle: 1.365 ± 0.064
1.027HisLys: 1.027 ± 0.047
1.762HisLeu: 1.762 ± 0.066
0.638HisMet: 0.638 ± 0.039
0.82HisAsn: 0.82 ± 0.04
1.103HisPro: 1.103 ± 0.051
0.681HisGln: 0.681 ± 0.041
0.962HisArg: 0.962 ± 0.043
1.299HisSer: 1.299 ± 0.049
1.471HisThr: 1.471 ± 0.06
1.492HisVal: 1.492 ± 0.057
0.223HisTrp: 0.223 ± 0.022
0.673HisTyr: 0.673 ± 0.036
0.0HisXaa: 0.0 ± 0.0
Ile
6.598IleAla: 6.598 ± 0.118
1.056IleCys: 1.056 ± 0.049
3.979IleAsp: 3.979 ± 0.097
3.72IleGlu: 3.72 ± 0.093
1.925IlePhe: 1.925 ± 0.069
4.297IleGly: 4.297 ± 0.091
1.078IleHis: 1.078 ± 0.041
3.313IleIle: 3.313 ± 0.112
2.625IleLys: 2.625 ± 0.078
4.712IleLeu: 4.712 ± 0.124
1.389IleMet: 1.389 ± 0.054
2.062IleAsn: 2.062 ± 0.062
2.801IlePro: 2.801 ± 0.081
1.878IleGln: 1.878 ± 0.07
2.652IleArg: 2.652 ± 0.081
4.157IleSer: 4.157 ± 0.098
3.74IleThr: 3.74 ± 0.092
4.743IleVal: 4.743 ± 0.116
0.514IleTrp: 0.514 ± 0.032
1.557IleTyr: 1.557 ± 0.052
0.0IleXaa: 0.0 ± 0.0
Lys
4.603LysAla: 4.603 ± 0.111
0.395LysCys: 0.395 ± 0.028
2.778LysAsp: 2.778 ± 0.078
2.891LysGlu: 2.891 ± 0.076
1.267LysPhe: 1.267 ± 0.059
3.102LysGly: 3.102 ± 0.08
1.113LysHis: 1.113 ± 0.045
2.645LysIle: 2.645 ± 0.074
2.899LysLys: 2.899 ± 0.091
4.485LysLeu: 4.485 ± 0.1
1.179LysMet: 1.179 ± 0.049
2.169LysAsn: 2.169 ± 0.07
2.341LysPro: 2.341 ± 0.078
2.316LysGln: 2.316 ± 0.076
2.897LysArg: 2.897 ± 0.076
2.717LysSer: 2.717 ± 0.082
3.515LysThr: 3.515 ± 0.102
3.243LysVal: 3.243 ± 0.078
0.428LysTrp: 0.428 ± 0.03
1.275LysTyr: 1.275 ± 0.05
0.0LysXaa: 0.0 ± 0.0
Leu
10.126LeuAla: 10.126 ± 0.158
1.461LeuCys: 1.461 ± 0.058
6.091LeuAsp: 6.091 ± 0.115
5.41LeuGlu: 5.41 ± 0.113
3.419LeuPhe: 3.419 ± 0.103
6.738LeuGly: 6.738 ± 0.124
1.976LeuHis: 1.976 ± 0.065
5.356LeuIle: 5.356 ± 0.121
3.91LeuLys: 3.91 ± 0.092
9.16LeuLeu: 9.16 ± 0.179
2.5LeuMet: 2.5 ± 0.076
2.979LeuAsn: 2.979 ± 0.084
3.965LeuPro: 3.965 ± 0.083
3.149LeuGln: 3.149 ± 0.093
4.489LeuArg: 4.489 ± 0.115
7.642LeuSer: 7.642 ± 0.127
5.563LeuThr: 5.563 ± 0.108
7.454LeuVal: 7.454 ± 0.123
0.812LeuTrp: 0.812 ± 0.037
2.613LeuTyr: 2.613 ± 0.074
0.0LeuXaa: 0.0 ± 0.0
Met
2.787MetAla: 2.787 ± 0.086
0.307MetCys: 0.307 ± 0.024
1.676MetAsp: 1.676 ± 0.053
1.377MetGlu: 1.377 ± 0.054
0.753MetPhe: 0.753 ± 0.044
1.944MetGly: 1.944 ± 0.063
0.599MetHis: 0.599 ± 0.041
1.219MetIle: 1.219 ± 0.062
1.052MetLys: 1.052 ± 0.047
2.498MetLeu: 2.498 ± 0.082
0.638MetMet: 0.638 ± 0.039
0.933MetAsn: 0.933 ± 0.041
1.254MetPro: 1.254 ± 0.048
1.088MetGln: 1.088 ± 0.045
1.473MetArg: 1.473 ± 0.059
2.04MetSer: 2.04 ± 0.07
1.375MetThr: 1.375 ± 0.049
1.895MetVal: 1.895 ± 0.058
0.217MetTrp: 0.217 ± 0.02
0.647MetTyr: 0.647 ± 0.036
0.0MetXaa: 0.0 ± 0.0
Asn
3.501AsnAla: 3.501 ± 0.094
0.424AsnCys: 0.424 ± 0.027
1.86AsnAsp: 1.86 ± 0.06
1.997AsnGlu: 1.997 ± 0.071
1.158AsnPhe: 1.158 ± 0.051
2.605AsnGly: 2.605 ± 0.086
0.7AsnHis: 0.7 ± 0.038
2.058AsnIle: 2.058 ± 0.072
1.831AsnLys: 1.831 ± 0.071
3.137AsnLeu: 3.137 ± 0.09
0.917AsnMet: 0.917 ± 0.039
1.553AsnAsn: 1.553 ± 0.077
2.187AsnPro: 2.187 ± 0.074
1.293AsnGln: 1.293 ± 0.057
1.557AsnArg: 1.557 ± 0.065
1.983AsnSer: 1.983 ± 0.064
2.343AsnThr: 2.343 ± 0.079
2.484AsnVal: 2.484 ± 0.069
0.366AsnTrp: 0.366 ± 0.023
1.091AsnTyr: 1.091 ± 0.046
0.0AsnXaa: 0.0 ± 0.0
Pro
3.9ProAla: 3.9 ± 0.088
0.473ProCys: 0.473 ± 0.026
2.527ProAsp: 2.527 ± 0.089
3.02ProGlu: 3.02 ± 0.089
1.549ProPhe: 1.549 ± 0.059
2.588ProGly: 2.588 ± 0.079
0.974ProHis: 0.974 ± 0.044
2.089ProIle: 2.089 ± 0.065
1.88ProLys: 1.88 ± 0.066
3.591ProLeu: 3.591 ± 0.085
0.792ProMet: 0.792 ± 0.04
1.455ProAsn: 1.455 ± 0.055
0.929ProPro: 0.929 ± 0.05
2.05ProGln: 2.05 ± 0.07
1.514ProArg: 1.514 ± 0.061
2.795ProSer: 2.795 ± 0.079
2.701ProThr: 2.701 ± 0.088
3.134ProVal: 3.134 ± 0.091
0.426ProTrp: 0.426 ± 0.034
1.365ProTyr: 1.365 ± 0.053
0.0ProXaa: 0.0 ± 0.0
Gln
4.761GlnAla: 4.761 ± 0.104
0.297GlnCys: 0.297 ± 0.028
2.31GlnAsp: 2.31 ± 0.079
2.251GlnGlu: 2.251 ± 0.072
1.172GlnPhe: 1.172 ± 0.051
2.425GlnGly: 2.425 ± 0.076
0.767GlnHis: 0.767 ± 0.034
2.265GlnIle: 2.265 ± 0.075
2.138GlnLys: 2.138 ± 0.071
4.157GlnLeu: 4.157 ± 0.106
1.095GlnMet: 1.095 ± 0.047
1.455GlnAsn: 1.455 ± 0.049
1.387GlnPro: 1.387 ± 0.059
2.021GlnGln: 2.021 ± 0.087
2.161GlnArg: 2.161 ± 0.072
2.463GlnSer: 2.463 ± 0.09
2.648GlnThr: 2.648 ± 0.076
2.815GlnVal: 2.815 ± 0.077
0.346GlnTrp: 0.346 ± 0.031
1.046GlnTyr: 1.046 ± 0.049
0.0GlnXaa: 0.0 ± 0.0
Arg
4.745ArgAla: 4.745 ± 0.115
0.618ArgCys: 0.618 ± 0.039
2.523ArgAsp: 2.523 ± 0.082
3.137ArgGlu: 3.137 ± 0.089
1.95ArgPhe: 1.95 ± 0.054
2.832ArgGly: 2.832 ± 0.078
1.013ArgHis: 1.013 ± 0.051
3.114ArgIle: 3.114 ± 0.089
2.527ArgLys: 2.527 ± 0.077
4.479ArgLeu: 4.479 ± 0.114
1.563ArgMet: 1.563 ± 0.047
1.657ArgAsn: 1.657 ± 0.052
1.862ArgPro: 1.862 ± 0.06
1.757ArgGln: 1.757 ± 0.063
2.834ArgArg: 2.834 ± 0.092
2.959ArgSer: 2.959 ± 0.083
2.738ArgThr: 2.738 ± 0.076
3.624ArgVal: 3.624 ± 0.098
0.532ArgTrp: 0.532 ± 0.03
1.741ArgTyr: 1.741 ± 0.071
0.0ArgXaa: 0.0 ± 0.0
Ser
6.445SerAla: 6.445 ± 0.127
1.017SerCys: 1.017 ± 0.05
3.906SerAsp: 3.906 ± 0.089
3.597SerGlu: 3.597 ± 0.088
3.085SerPhe: 3.085 ± 0.077
5.045SerGly: 5.045 ± 0.116
1.471SerHis: 1.471 ± 0.059
3.949SerIle: 3.949 ± 0.097
3.104SerLys: 3.104 ± 0.08
6.171SerLeu: 6.171 ± 0.111
1.659SerMet: 1.659 ± 0.059
2.437SerAsn: 2.437 ± 0.07
2.015SerPro: 2.015 ± 0.067
2.535SerGln: 2.535 ± 0.073
2.977SerArg: 2.977 ± 0.085
4.872SerSer: 4.872 ± 0.113
3.828SerThr: 3.828 ± 0.096
4.653SerVal: 4.653 ± 0.105
0.837SerTrp: 0.837 ± 0.039
2.547SerTyr: 2.547 ± 0.077
0.0SerXaa: 0.0 ± 0.0
Thr
5.874ThrAla: 5.874 ± 0.13
0.726ThrCys: 0.726 ± 0.038
3.523ThrAsp: 3.523 ± 0.084
2.909ThrGlu: 2.909 ± 0.079
2.048ThrPhe: 2.048 ± 0.072
4.507ThrGly: 4.507 ± 0.107
1.385ThrHis: 1.385 ± 0.056
3.879ThrIle: 3.879 ± 0.1
2.805ThrLys: 2.805 ± 0.087
5.655ThrLeu: 5.655 ± 0.11
1.33ThrMet: 1.33 ± 0.052
2.406ThrAsn: 2.406 ± 0.086
3.302ThrPro: 3.302 ± 0.092
2.551ThrGln: 2.551 ± 0.075
2.611ThrArg: 2.611 ± 0.072
4.209ThrSer: 4.209 ± 0.1
4.025ThrThr: 4.025 ± 0.101
4.366ThrVal: 4.366 ± 0.098
0.614ThrTrp: 0.614 ± 0.04
1.809ThrTyr: 1.809 ± 0.068
0.0ThrXaa: 0.0 ± 0.0
Val
7.699ValAla: 7.699 ± 0.144
1.498ValCys: 1.498 ± 0.057
4.691ValAsp: 4.691 ± 0.097
4.219ValGlu: 4.219 ± 0.101
2.809ValPhe: 2.809 ± 0.08
5.285ValGly: 5.285 ± 0.125
1.557ValHis: 1.557 ± 0.054
4.313ValIle: 4.313 ± 0.09
2.948ValLys: 2.948 ± 0.088
7.507ValLeu: 7.507 ± 0.142
1.846ValMet: 1.846 ± 0.062
2.351ValAsn: 2.351 ± 0.07
3.171ValPro: 3.171 ± 0.074
2.504ValGln: 2.504 ± 0.067
3.765ValArg: 3.765 ± 0.092
5.481ValSer: 5.481 ± 0.109
4.166ValThr: 4.166 ± 0.1
6.504ValVal: 6.504 ± 0.168
0.692ValTrp: 0.692 ± 0.039
2.128ValTyr: 2.128 ± 0.074
0.0ValXaa: 0.0 ± 0.0
Trp
0.822TrpAla: 0.822 ± 0.037
0.178TrpCys: 0.178 ± 0.018
0.628TrpAsp: 0.628 ± 0.041
0.597TrpGlu: 0.597 ± 0.037
0.464TrpPhe: 0.464 ± 0.038
0.751TrpGly: 0.751 ± 0.041
0.307TrpHis: 0.307 ± 0.027
0.593TrpIle: 0.593 ± 0.033
0.452TrpLys: 0.452 ± 0.031
1.115TrpLeu: 1.115 ± 0.049
0.329TrpMet: 0.329 ± 0.028
0.438TrpAsn: 0.438 ± 0.032
0.379TrpPro: 0.379 ± 0.026
0.452TrpGln: 0.452 ± 0.033
0.497TrpArg: 0.497 ± 0.033
0.649TrpSer: 0.649 ± 0.04
0.544TrpThr: 0.544 ± 0.037
0.6TrpVal: 0.6 ± 0.038
0.141TrpTrp: 0.141 ± 0.017
0.403TrpTyr: 0.403 ± 0.047
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.024TyrAla: 3.024 ± 0.083
0.421TyrCys: 0.421 ± 0.031
2.04TyrAsp: 2.04 ± 0.071
1.983TyrGlu: 1.983 ± 0.07
1.197TyrPhe: 1.197 ± 0.059
2.273TyrGly: 2.273 ± 0.066
0.634TyrHis: 0.634 ± 0.038
1.633TyrIle: 1.633 ± 0.057
1.395TyrLys: 1.395 ± 0.055
2.926TyrLeu: 2.926 ± 0.076
0.634TyrMet: 0.634 ± 0.037
1.107TyrAsn: 1.107 ± 0.059
1.228TyrPro: 1.228 ± 0.052
1.129TyrGln: 1.129 ± 0.054
1.573TyrArg: 1.573 ± 0.057
1.807TyrSer: 1.807 ± 0.07
2.068TyrThr: 2.068 ± 0.068
2.148TyrVal: 2.148 ± 0.065
0.297TyrTrp: 0.297 ± 0.029
0.978TyrTyr: 0.978 ± 0.055
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1539 proteins (511244 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski