Amino acid dipepetide frequency for Changjiang tombus-like virus 12

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.24AlaAla: 12.24 ± 5.947
1.224AlaCys: 1.224 ± 1.168
3.672AlaAsp: 3.672 ± 0.317
2.448AlaGlu: 2.448 ± 0.425
3.672AlaPhe: 3.672 ± 2.227
6.12AlaGly: 6.12 ± 2.019
1.224AlaHis: 1.224 ± 1.168
8.568AlaIle: 8.568 ± 2.444
2.448AlaLys: 2.448 ± 1.484
8.568AlaLeu: 8.568 ± 1.376
0.0AlaMet: 0.0 ± 0.0
6.12AlaAsn: 6.12 ± 0.109
9.792AlaPro: 9.792 ± 5.521
2.448AlaGln: 2.448 ± 0.425
11.016AlaArg: 11.016 ± 4.77
4.896AlaSer: 4.896 ± 0.851
8.568AlaThr: 8.568 ± 0.534
8.568AlaVal: 8.568 ± 4.354
1.224AlaTrp: 1.224 ± 0.742
7.344AlaTyr: 7.344 ± 0.633
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.224CysPhe: 1.224 ± 0.742
1.224CysGly: 1.224 ± 1.168
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.224CysGln: 1.224 ± 0.742
1.224CysArg: 1.224 ± 0.742
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
2.448CysVal: 2.448 ± 0.425
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.12AspAla: 6.12 ± 0.109
0.0AspCys: 0.0 ± 0.0
1.224AspAsp: 1.224 ± 0.742
2.448AspGlu: 2.448 ± 1.484
1.224AspPhe: 1.224 ± 1.168
3.672AspGly: 3.672 ± 2.227
2.448AspHis: 2.448 ± 1.484
0.0AspIle: 0.0 ± 0.0
1.224AspLys: 1.224 ± 0.742
2.448AspLeu: 2.448 ± 1.484
2.448AspMet: 2.448 ± 1.484
0.0AspAsn: 0.0 ± 0.0
2.448AspPro: 2.448 ± 0.425
2.448AspGln: 2.448 ± 1.484
1.224AspArg: 1.224 ± 1.168
4.896AspSer: 4.896 ± 1.059
4.896AspThr: 4.896 ± 1.059
2.448AspVal: 2.448 ± 1.484
0.0AspTrp: 0.0 ± 0.0
1.224AspTyr: 1.224 ± 0.742
0.0AspXaa: 0.0 ± 0.0
Glu
2.448GluAla: 2.448 ± 0.425
0.0GluCys: 0.0 ± 0.0
1.224GluAsp: 1.224 ± 0.742
3.672GluGlu: 3.672 ± 0.317
1.224GluPhe: 1.224 ± 0.742
2.448GluGly: 2.448 ± 0.425
3.672GluHis: 3.672 ± 2.227
1.224GluIle: 1.224 ± 0.742
3.672GluLys: 3.672 ± 0.317
2.448GluLeu: 2.448 ± 1.484
2.448GluMet: 2.448 ± 0.425
1.224GluAsn: 1.224 ± 0.742
3.672GluPro: 3.672 ± 2.227
4.896GluGln: 4.896 ± 1.059
6.12GluArg: 6.12 ± 1.801
2.448GluSer: 2.448 ± 1.484
2.448GluThr: 2.448 ± 2.335
4.896GluVal: 4.896 ± 1.059
1.224GluTrp: 1.224 ± 0.742
1.224GluTyr: 1.224 ± 1.168
0.0GluXaa: 0.0 ± 0.0
Phe
2.448PheAla: 2.448 ± 0.425
1.224PheCys: 1.224 ± 0.742
2.448PheAsp: 2.448 ± 1.484
1.224PheGlu: 1.224 ± 0.742
0.0PhePhe: 0.0 ± 0.0
1.224PheGly: 1.224 ± 0.742
0.0PheHis: 0.0 ± 0.0
2.448PheIle: 2.448 ± 0.425
0.0PheLys: 0.0 ± 0.0
1.224PheLeu: 1.224 ± 0.742
1.224PheMet: 1.224 ± 0.742
1.224PheAsn: 1.224 ± 1.168
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
2.448PheArg: 2.448 ± 1.484
0.0PheSer: 0.0 ± 0.0
4.896PheThr: 4.896 ± 2.761
3.672PheVal: 3.672 ± 1.593
1.224PheTrp: 1.224 ± 0.742
2.448PheTyr: 2.448 ± 1.484
0.0PheXaa: 0.0 ± 0.0
Gly
8.568GlyAla: 8.568 ± 0.534
0.0GlyCys: 0.0 ± 0.0
6.12GlyAsp: 6.12 ± 1.801
1.224GlyGlu: 1.224 ± 1.168
3.672GlyPhe: 3.672 ± 0.317
6.12GlyGly: 6.12 ± 1.801
1.224GlyHis: 1.224 ± 1.168
3.672GlyIle: 3.672 ± 2.227
1.224GlyLys: 1.224 ± 0.742
6.12GlyLeu: 6.12 ± 2.019
4.896GlyMet: 4.896 ± 0.49
3.672GlyAsn: 3.672 ± 0.317
2.448GlyPro: 2.448 ± 2.335
6.12GlyGln: 6.12 ± 0.109
3.672GlyArg: 3.672 ± 2.227
4.896GlySer: 4.896 ± 0.851
7.344GlyThr: 7.344 ± 3.186
8.568GlyVal: 8.568 ± 2.444
0.0GlyTrp: 0.0 ± 0.0
4.896GlyTyr: 4.896 ± 0.851
0.0GlyXaa: 0.0 ± 0.0
His
3.672HisAla: 3.672 ± 2.227
0.0HisCys: 0.0 ± 0.0
1.224HisAsp: 1.224 ± 0.742
3.672HisGlu: 3.672 ± 2.227
0.0HisPhe: 0.0 ± 0.0
2.448HisGly: 2.448 ± 0.425
0.0HisHis: 0.0 ± 0.0
1.224HisIle: 1.224 ± 0.742
0.0HisLys: 0.0 ± 0.0
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
1.224HisAsn: 1.224 ± 1.168
1.224HisPro: 1.224 ± 0.742
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.224HisSer: 1.224 ± 0.742
1.224HisThr: 1.224 ± 0.742
0.0HisVal: 0.0 ± 0.0
2.448HisTrp: 2.448 ± 0.425
2.448HisTyr: 2.448 ± 0.425
0.0HisXaa: 0.0 ± 0.0
Ile
1.224IleAla: 1.224 ± 1.168
0.0IleCys: 0.0 ± 0.0
2.448IleAsp: 2.448 ± 1.484
1.224IleGlu: 1.224 ± 1.168
0.0IlePhe: 0.0 ± 0.0
4.896IleGly: 4.896 ± 0.851
1.224IleHis: 1.224 ± 0.742
0.0IleIle: 0.0 ± 0.0
2.448IleLys: 2.448 ± 1.484
2.448IleLeu: 2.448 ± 0.425
2.448IleMet: 2.448 ± 0.414
2.448IleAsn: 2.448 ± 0.425
1.224IlePro: 1.224 ± 0.742
0.0IleGln: 0.0 ± 0.0
1.224IleArg: 1.224 ± 0.742
4.896IleSer: 4.896 ± 1.059
3.672IleThr: 3.672 ± 1.593
0.0IleVal: 0.0 ± 0.0
1.224IleTrp: 1.224 ± 0.742
1.224IleTyr: 1.224 ± 1.168
0.0IleXaa: 0.0 ± 0.0
Lys
9.792LysAla: 9.792 ± 5.938
0.0LysCys: 0.0 ± 0.0
2.448LysAsp: 2.448 ± 1.484
1.224LysGlu: 1.224 ± 0.742
2.448LysPhe: 2.448 ± 1.484
6.12LysGly: 6.12 ± 1.801
1.224LysHis: 1.224 ± 0.742
2.448LysIle: 2.448 ± 1.484
2.448LysLys: 2.448 ± 1.484
2.448LysLeu: 2.448 ± 2.335
0.0LysMet: 0.0 ± 0.0
0.0LysAsn: 0.0 ± 0.0
0.0LysPro: 0.0 ± 0.0
1.224LysGln: 1.224 ± 0.742
2.448LysArg: 2.448 ± 2.335
1.224LysSer: 1.224 ± 0.742
2.448LysThr: 2.448 ± 0.425
1.224LysVal: 1.224 ± 1.168
2.448LysTrp: 2.448 ± 0.425
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
11.016LeuAla: 11.016 ± 2.869
0.0LeuCys: 0.0 ± 0.0
2.448LeuAsp: 2.448 ± 0.425
4.896LeuGlu: 4.896 ± 2.969
0.0LeuPhe: 0.0 ± 0.0
11.016LeuGly: 11.016 ± 0.96
1.224LeuHis: 1.224 ± 0.742
3.672LeuIle: 3.672 ± 0.317
4.896LeuLys: 4.896 ± 1.059
7.344LeuLeu: 7.344 ± 1.276
0.0LeuMet: 0.0 ± 0.0
0.0LeuAsn: 0.0 ± 0.0
4.896LeuPro: 4.896 ± 1.059
2.448LeuGln: 2.448 ± 1.484
3.672LeuArg: 3.672 ± 0.317
8.568LeuSer: 8.568 ± 1.376
0.0LeuThr: 0.0 ± 0.0
6.12LeuVal: 6.12 ± 0.109
0.0LeuTrp: 0.0 ± 0.0
3.672LeuTyr: 3.672 ± 0.317
0.0LeuXaa: 0.0 ± 0.0
Met
3.672MetAla: 3.672 ± 0.317
0.0MetCys: 0.0 ± 0.0
1.224MetAsp: 1.224 ± 1.168
3.672MetGlu: 3.672 ± 2.227
0.0MetPhe: 0.0 ± 0.0
2.448MetGly: 2.448 ± 0.425
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.224MetLys: 1.224 ± 0.742
1.224MetLeu: 1.224 ± 0.742
0.0MetMet: 0.0 ± 0.0
1.224MetAsn: 1.224 ± 0.742
2.448MetPro: 2.448 ± 0.425
1.224MetGln: 1.224 ± 0.742
1.224MetArg: 1.224 ± 1.168
1.224MetSer: 1.224 ± 0.742
0.0MetThr: 0.0 ± 0.0
3.672MetVal: 3.672 ± 1.593
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.896AsnAla: 4.896 ± 4.671
1.224AsnCys: 1.224 ± 0.742
2.448AsnAsp: 2.448 ± 0.425
1.224AsnGlu: 1.224 ± 1.168
1.224AsnPhe: 1.224 ± 1.168
1.224AsnGly: 1.224 ± 1.168
0.0AsnHis: 0.0 ± 0.0
1.224AsnIle: 1.224 ± 0.742
0.0AsnLys: 0.0 ± 0.0
3.672AsnLeu: 3.672 ± 0.317
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
3.672AsnPro: 3.672 ± 1.593
2.448AsnGln: 2.448 ± 0.425
2.448AsnArg: 2.448 ± 2.335
1.224AsnSer: 1.224 ± 1.168
1.224AsnThr: 1.224 ± 0.742
2.448AsnVal: 2.448 ± 1.484
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.224ProAla: 1.224 ± 1.168
1.224ProCys: 1.224 ± 1.168
0.0ProAsp: 0.0 ± 0.0
3.672ProGlu: 3.672 ± 2.227
0.0ProPhe: 0.0 ± 0.0
3.672ProGly: 3.672 ± 1.593
0.0ProHis: 0.0 ± 0.0
0.0ProIle: 0.0 ± 0.0
3.672ProLys: 3.672 ± 0.317
8.568ProLeu: 8.568 ± 0.534
0.0ProMet: 0.0 ± 0.0
1.224ProAsn: 1.224 ± 1.168
2.448ProPro: 2.448 ± 0.425
0.0ProGln: 0.0 ± 0.0
6.12ProArg: 6.12 ± 2.019
6.12ProSer: 6.12 ± 0.109
3.672ProThr: 3.672 ± 1.593
7.344ProVal: 7.344 ± 1.276
1.224ProTrp: 1.224 ± 0.742
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.448GlnAla: 2.448 ± 1.484
1.224GlnCys: 1.224 ± 0.742
3.672GlnAsp: 3.672 ± 2.227
0.0GlnGlu: 0.0 ± 0.0
2.448GlnPhe: 2.448 ± 1.484
1.224GlnGly: 1.224 ± 1.168
2.448GlnHis: 2.448 ± 1.484
2.448GlnIle: 2.448 ± 0.425
1.224GlnLys: 1.224 ± 0.742
1.224GlnLeu: 1.224 ± 0.742
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.224GlnPro: 1.224 ± 0.742
0.0GlnGln: 0.0 ± 0.0
4.896GlnArg: 4.896 ± 1.059
2.448GlnSer: 2.448 ± 0.425
2.448GlnThr: 2.448 ± 0.425
4.896GlnVal: 4.896 ± 0.851
0.0GlnTrp: 0.0 ± 0.0
3.672GlnTyr: 3.672 ± 0.317
0.0GlnXaa: 0.0 ± 0.0
Arg
4.896ArgAla: 4.896 ± 0.851
1.224ArgCys: 1.224 ± 0.742
1.224ArgAsp: 1.224 ± 0.742
2.448ArgGlu: 2.448 ± 1.484
2.448ArgPhe: 2.448 ± 0.425
4.896ArgGly: 4.896 ± 0.851
1.224ArgHis: 1.224 ± 0.742
1.224ArgIle: 1.224 ± 1.168
3.672ArgLys: 3.672 ± 1.593
7.344ArgLeu: 7.344 ± 2.543
6.12ArgMet: 6.12 ± 2.019
2.448ArgAsn: 2.448 ± 0.425
2.448ArgPro: 2.448 ± 0.425
0.0ArgGln: 0.0 ± 0.0
4.896ArgArg: 4.896 ± 1.059
1.224ArgSer: 1.224 ± 0.742
4.896ArgThr: 4.896 ± 1.059
6.12ArgVal: 6.12 ± 2.019
1.224ArgTrp: 1.224 ± 0.742
6.12ArgTyr: 6.12 ± 3.711
0.0ArgXaa: 0.0 ± 0.0
Ser
12.24SerAla: 12.24 ± 0.217
0.0SerCys: 0.0 ± 0.0
0.0SerAsp: 0.0 ± 0.0
4.896SerGlu: 4.896 ± 1.059
2.448SerPhe: 2.448 ± 0.425
1.224SerGly: 1.224 ± 0.742
1.224SerHis: 1.224 ± 1.168
1.224SerIle: 1.224 ± 1.168
6.12SerLys: 6.12 ± 1.801
3.672SerLeu: 3.672 ± 2.227
0.0SerMet: 0.0 ± 0.0
3.672SerAsn: 3.672 ± 3.503
1.224SerPro: 1.224 ± 0.742
0.0SerGln: 0.0 ± 0.0
3.672SerArg: 3.672 ± 0.317
4.896SerSer: 4.896 ± 2.969
6.12SerThr: 6.12 ± 3.928
7.344SerVal: 7.344 ± 2.543
3.672SerTrp: 3.672 ± 2.227
1.224SerTyr: 1.224 ± 0.742
0.0SerXaa: 0.0 ± 0.0
Thr
7.344ThrAla: 7.344 ± 1.276
0.0ThrCys: 0.0 ± 0.0
3.672ThrAsp: 3.672 ± 0.317
4.896ThrGlu: 4.896 ± 2.761
3.672ThrPhe: 3.672 ± 1.593
8.568ThrGly: 8.568 ± 0.534
1.224ThrHis: 1.224 ± 0.742
2.448ThrIle: 2.448 ± 0.425
1.224ThrLys: 1.224 ± 0.742
6.12ThrLeu: 6.12 ± 3.928
2.448ThrMet: 2.448 ± 1.484
1.224ThrAsn: 1.224 ± 1.168
7.344ThrPro: 7.344 ± 3.186
2.448ThrGln: 2.448 ± 0.425
3.672ThrArg: 3.672 ± 1.593
2.448ThrSer: 2.448 ± 2.335
7.344ThrThr: 7.344 ± 3.186
4.896ThrVal: 4.896 ± 4.671
2.448ThrTrp: 2.448 ± 1.484
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
8.568ValAla: 8.568 ± 2.444
0.0ValCys: 0.0 ± 0.0
4.896ValAsp: 4.896 ± 1.059
6.12ValGlu: 6.12 ± 1.801
2.448ValPhe: 2.448 ± 1.484
7.344ValGly: 7.344 ± 3.186
1.224ValHis: 1.224 ± 0.742
1.224ValIle: 1.224 ± 0.742
4.896ValLys: 4.896 ± 0.851
7.344ValLeu: 7.344 ± 0.633
0.0ValMet: 0.0 ± 0.0
3.672ValAsn: 3.672 ± 3.503
1.224ValPro: 1.224 ± 1.168
3.672ValGln: 3.672 ± 0.317
4.896ValArg: 4.896 ± 0.851
7.344ValSer: 7.344 ± 1.276
7.344ValThr: 7.344 ± 5.096
11.016ValVal: 11.016 ± 2.869
0.0ValTrp: 0.0 ± 0.0
4.896ValTyr: 4.896 ± 0.851
0.0ValXaa: 0.0 ± 0.0
Trp
2.448TrpAla: 2.448 ± 1.484
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.224TrpGlu: 1.224 ± 0.742
0.0TrpPhe: 0.0 ± 0.0
2.448TrpGly: 2.448 ± 1.484
2.448TrpHis: 2.448 ± 0.425
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
2.448TrpLeu: 2.448 ± 1.484
1.224TrpMet: 1.224 ± 0.742
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.224TrpGln: 1.224 ± 0.742
0.0TrpArg: 0.0 ± 0.0
1.224TrpSer: 1.224 ± 0.742
2.448TrpThr: 2.448 ± 0.425
1.224TrpVal: 1.224 ± 0.742
1.224TrpTrp: 1.224 ± 1.168
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.896TyrAla: 4.896 ± 2.761
0.0TyrCys: 0.0 ± 0.0
2.448TyrAsp: 2.448 ± 1.484
2.448TyrGlu: 2.448 ± 0.425
1.224TyrPhe: 1.224 ± 1.168
6.12TyrGly: 6.12 ± 0.109
0.0TyrHis: 0.0 ± 0.0
2.448TyrIle: 2.448 ± 0.425
1.224TyrLys: 1.224 ± 0.742
1.224TyrLeu: 1.224 ± 0.742
0.0TyrMet: 0.0 ± 0.0
1.224TyrAsn: 1.224 ± 0.742
2.448TyrPro: 2.448 ± 1.484
6.12TyrGln: 6.12 ± 1.801
1.224TyrArg: 1.224 ± 0.742
3.672TyrSer: 3.672 ± 0.317
2.448TyrThr: 2.448 ± 0.425
1.224TyrVal: 1.224 ± 0.742
0.0TyrTrp: 0.0 ± 0.0
3.672TyrTyr: 3.672 ± 0.317
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (818 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski