Amino acid dipepetide frequency for Alloscardovia macacae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.337AlaAla: 12.337 ± 0.236
0.911AlaCys: 0.911 ± 0.042
6.718AlaAsp: 6.718 ± 0.147
6.548AlaGlu: 6.548 ± 0.126
3.711AlaPhe: 3.711 ± 0.087
8.369AlaGly: 8.369 ± 0.137
2.757AlaHis: 2.757 ± 0.083
4.673AlaIle: 4.673 ± 0.094
3.975AlaLys: 3.975 ± 0.107
11.053AlaLeu: 11.053 ± 0.174
2.621AlaMet: 2.621 ± 0.071
3.014AlaAsn: 3.014 ± 0.081
3.986AlaPro: 3.986 ± 0.097
5.605AlaGln: 5.605 ± 0.128
6.601AlaArg: 6.601 ± 0.143
6.98AlaSer: 6.98 ± 0.15
5.625AlaThr: 5.625 ± 0.11
8.625AlaVal: 8.625 ± 0.16
1.416AlaTrp: 1.416 ± 0.05
3.066AlaTyr: 3.066 ± 0.072
0.0AlaXaa: 0.0 ± 0.0
Cys
0.989CysAla: 0.989 ± 0.041
0.066CysCys: 0.066 ± 0.011
0.418CysAsp: 0.418 ± 0.028
0.466CysGlu: 0.466 ± 0.028
0.255CysPhe: 0.255 ± 0.025
0.775CysGly: 0.775 ± 0.039
0.177CysHis: 0.177 ± 0.022
0.45CysIle: 0.45 ± 0.032
0.154CysLys: 0.154 ± 0.02
0.564CysLeu: 0.564 ± 0.031
0.2CysMet: 0.2 ± 0.019
0.159CysAsn: 0.159 ± 0.016
0.412CysPro: 0.412 ± 0.03
0.187CysGln: 0.187 ± 0.02
0.327CysArg: 0.327 ± 0.027
0.475CysSer: 0.475 ± 0.034
0.493CysThr: 0.493 ± 0.03
0.693CysVal: 0.693 ± 0.045
0.098CysTrp: 0.098 ± 0.014
0.189CysTyr: 0.189 ± 0.018
0.0CysXaa: 0.0 ± 0.0
Asp
7.166AspAla: 7.166 ± 0.147
0.391AspCys: 0.391 ± 0.026
3.409AspAsp: 3.409 ± 0.097
4.746AspGlu: 4.746 ± 0.112
2.366AspPhe: 2.366 ± 0.077
5.064AspGly: 5.064 ± 0.125
1.039AspHis: 1.039 ± 0.049
3.666AspIle: 3.666 ± 0.087
2.034AspLys: 2.034 ± 0.065
4.493AspLeu: 4.493 ± 0.102
1.589AspMet: 1.589 ± 0.051
1.528AspAsn: 1.528 ± 0.057
2.814AspPro: 2.814 ± 0.083
1.536AspGln: 1.536 ± 0.051
2.534AspArg: 2.534 ± 0.073
3.544AspSer: 3.544 ± 0.085
3.887AspThr: 3.887 ± 0.089
5.334AspVal: 5.334 ± 0.096
0.782AspTrp: 0.782 ± 0.036
1.834AspTyr: 1.834 ± 0.055
0.0AspXaa: 0.0 ± 0.0
Glu
6.26GluAla: 6.26 ± 0.133
0.382GluCys: 0.382 ± 0.026
3.966GluAsp: 3.966 ± 0.095
4.312GluGlu: 4.312 ± 0.115
1.995GluPhe: 1.995 ± 0.07
4.28GluGly: 4.28 ± 0.106
1.566GluHis: 1.566 ± 0.066
2.893GluIle: 2.893 ± 0.087
3.4GluLys: 3.4 ± 0.089
5.934GluLeu: 5.934 ± 0.107
1.564GluMet: 1.564 ± 0.055
2.611GluAsn: 2.611 ± 0.071
2.328GluPro: 2.328 ± 0.073
2.611GluGln: 2.611 ± 0.077
4.184GluArg: 4.184 ± 0.104
3.623GluSer: 3.623 ± 0.083
3.141GluThr: 3.141 ± 0.082
4.15GluVal: 4.15 ± 0.096
0.704GluTrp: 0.704 ± 0.041
1.998GluTyr: 1.998 ± 0.067
0.002GluXaa: 0.002 ± 0.002
Phe
3.916PheAla: 3.916 ± 0.094
0.295PheCys: 0.295 ± 0.025
2.302PheAsp: 2.302 ± 0.067
2.228PheGlu: 2.228 ± 0.07
1.453PhePhe: 1.453 ± 0.063
3.261PheGly: 3.261 ± 0.083
0.723PheHis: 0.723 ± 0.038
1.996PheIle: 1.996 ± 0.066
0.952PheLys: 0.952 ± 0.045
3.064PheLeu: 3.064 ± 0.097
0.868PheMet: 0.868 ± 0.044
1.105PheAsn: 1.105 ± 0.046
1.295PhePro: 1.295 ± 0.052
0.918PheGln: 0.918 ± 0.046
1.443PheArg: 1.443 ± 0.051
2.728PheSer: 2.728 ± 0.074
2.757PheThr: 2.757 ± 0.087
2.784PheVal: 2.784 ± 0.075
0.482PheTrp: 0.482 ± 0.028
1.071PheTyr: 1.071 ± 0.047
0.0PheXaa: 0.0 ± 0.0
Gly
7.555GlyAla: 7.555 ± 0.137
0.596GlyCys: 0.596 ± 0.034
3.646GlyAsp: 3.646 ± 0.1
4.655GlyGlu: 4.655 ± 0.111
3.073GlyPhe: 3.073 ± 0.088
5.489GlyGly: 5.489 ± 0.116
1.643GlyHis: 1.643 ± 0.055
4.591GlyIle: 4.591 ± 0.104
3.468GlyLys: 3.468 ± 0.089
6.659GlyLeu: 6.659 ± 0.134
2.061GlyMet: 2.061 ± 0.068
2.289GlyAsn: 2.289 ± 0.073
2.078GlyPro: 2.078 ± 0.066
3.019GlyGln: 3.019 ± 0.083
4.018GlyArg: 4.018 ± 0.096
5.341GlySer: 5.341 ± 0.14
4.96GlyThr: 4.96 ± 0.121
6.38GlyVal: 6.38 ± 0.123
1.105GlyTrp: 1.105 ± 0.046
2.641GlyTyr: 2.641 ± 0.082
0.0GlyXaa: 0.0 ± 0.0
His
2.478HisAla: 2.478 ± 0.077
0.166HisCys: 0.166 ± 0.016
1.354HisAsp: 1.354 ± 0.05
1.389HisGlu: 1.389 ± 0.051
0.791HisPhe: 0.791 ± 0.04
1.625HisGly: 1.625 ± 0.063
0.564HisHis: 0.564 ± 0.038
1.359HisIle: 1.359 ± 0.049
0.705HisLys: 0.705 ± 0.038
1.689HisLeu: 1.689 ± 0.06
0.595HisMet: 0.595 ± 0.038
0.616HisAsn: 0.616 ± 0.033
1.232HisPro: 1.232 ± 0.055
0.695HisGln: 0.695 ± 0.038
1.171HisArg: 1.171 ± 0.05
1.293HisSer: 1.293 ± 0.049
1.605HisThr: 1.605 ± 0.06
2.016HisVal: 2.016 ± 0.065
0.329HisTrp: 0.329 ± 0.025
0.648HisTyr: 0.648 ± 0.034
0.0HisXaa: 0.0 ± 0.0
Ile
5.643IleAla: 5.643 ± 0.12
0.487IleCys: 0.487 ± 0.029
3.471IleAsp: 3.471 ± 0.085
2.962IleGlu: 2.962 ± 0.083
1.998IlePhe: 1.998 ± 0.074
3.637IleGly: 3.637 ± 0.098
1.232IleHis: 1.232 ± 0.049
3.177IleIle: 3.177 ± 0.104
1.541IleLys: 1.541 ± 0.053
4.937IleLeu: 4.937 ± 0.117
1.196IleMet: 1.196 ± 0.049
1.605IleAsn: 1.605 ± 0.062
2.912IlePro: 2.912 ± 0.076
1.803IleGln: 1.803 ± 0.057
2.998IleArg: 2.998 ± 0.076
3.773IleSer: 3.773 ± 0.089
3.566IleThr: 3.566 ± 0.091
4.102IleVal: 4.102 ± 0.104
0.529IleTrp: 0.529 ± 0.034
1.259IleTyr: 1.259 ± 0.05
0.0IleXaa: 0.0 ± 0.0
Lys
4.137LysAla: 4.137 ± 0.101
0.148LysCys: 0.148 ± 0.016
2.536LysAsp: 2.536 ± 0.073
2.236LysGlu: 2.236 ± 0.081
1.032LysPhe: 1.032 ± 0.047
2.398LysGly: 2.398 ± 0.075
0.795LysHis: 0.795 ± 0.038
1.884LysIle: 1.884 ± 0.061
2.328LysLys: 2.328 ± 0.08
3.366LysLeu: 3.366 ± 0.081
0.905LysMet: 0.905 ± 0.041
1.816LysAsn: 1.816 ± 0.064
1.75LysPro: 1.75 ± 0.062
1.352LysGln: 1.352 ± 0.053
2.345LysArg: 2.345 ± 0.069
2.368LysSer: 2.368 ± 0.072
2.62LysThr: 2.62 ± 0.073
2.543LysVal: 2.543 ± 0.075
0.434LysTrp: 0.434 ± 0.026
1.13LysTyr: 1.13 ± 0.047
0.002LysXaa: 0.002 ± 0.002
Leu
10.149LeuAla: 10.149 ± 0.15
0.846LeuCys: 0.846 ± 0.039
5.739LeuAsp: 5.739 ± 0.123
5.012LeuGlu: 5.012 ± 0.103
3.102LeuPhe: 3.102 ± 0.088
7.059LeuGly: 7.059 ± 0.143
1.966LeuHis: 1.966 ± 0.061
4.528LeuIle: 4.528 ± 0.109
3.314LeuLys: 3.314 ± 0.086
8.057LeuLeu: 8.057 ± 0.18
2.073LeuMet: 2.073 ± 0.071
3.143LeuAsn: 3.143 ± 0.073
4.221LeuPro: 4.221 ± 0.089
2.595LeuGln: 2.595 ± 0.069
5.009LeuArg: 5.009 ± 0.099
6.8LeuSer: 6.8 ± 0.117
6.2LeuThr: 6.2 ± 0.129
6.619LeuVal: 6.619 ± 0.131
1.111LeuTrp: 1.111 ± 0.05
2.373LeuTyr: 2.373 ± 0.071
0.0LeuXaa: 0.0 ± 0.0
Met
2.609MetAla: 2.609 ± 0.072
0.214MetCys: 0.214 ± 0.018
1.32MetAsp: 1.32 ± 0.056
1.17MetGlu: 1.17 ± 0.052
0.675MetPhe: 0.675 ± 0.033
1.702MetGly: 1.702 ± 0.063
0.516MetHis: 0.516 ± 0.036
1.154MetIle: 1.154 ± 0.056
1.175MetLys: 1.175 ± 0.044
2.209MetLeu: 2.209 ± 0.062
0.659MetMet: 0.659 ± 0.039
1.102MetAsn: 1.102 ± 0.047
1.293MetPro: 1.293 ± 0.048
0.757MetGln: 0.757 ± 0.038
1.609MetArg: 1.609 ± 0.057
1.934MetSer: 1.934 ± 0.068
1.877MetThr: 1.877 ± 0.058
1.68MetVal: 1.68 ± 0.063
0.291MetTrp: 0.291 ± 0.023
0.614MetTyr: 0.614 ± 0.035
0.0MetXaa: 0.0 ± 0.0
Asn
3.853AsnAla: 3.853 ± 0.094
0.195AsnCys: 0.195 ± 0.021
1.752AsnAsp: 1.752 ± 0.072
1.862AsnGlu: 1.862 ± 0.062
1.179AsnPhe: 1.179 ± 0.05
2.889AsnGly: 2.889 ± 0.081
0.62AsnHis: 0.62 ± 0.03
1.712AsnIle: 1.712 ± 0.064
1.077AsnLys: 1.077 ± 0.049
2.682AsnLeu: 2.682 ± 0.064
0.805AsnMet: 0.805 ± 0.04
1.03AsnAsn: 1.03 ± 0.053
2.011AsnPro: 2.011 ± 0.056
0.939AsnGln: 0.939 ± 0.046
1.636AsnArg: 1.636 ± 0.065
2.039AsnSer: 2.039 ± 0.072
2.152AsnThr: 2.152 ± 0.08
2.784AsnVal: 2.784 ± 0.078
0.489AsnTrp: 0.489 ± 0.031
0.971AsnTyr: 0.971 ± 0.046
0.0AsnXaa: 0.0 ± 0.0
Pro
4.63ProAla: 4.63 ± 0.12
0.246ProCys: 0.246 ± 0.022
2.968ProAsp: 2.968 ± 0.077
3.353ProGlu: 3.353 ± 0.086
1.534ProPhe: 1.534 ± 0.054
2.964ProGly: 2.964 ± 0.079
1.077ProHis: 1.077 ± 0.054
1.659ProIle: 1.659 ± 0.06
1.371ProLys: 1.371 ± 0.054
3.814ProLeu: 3.814 ± 0.081
0.75ProMet: 0.75 ± 0.039
1.243ProAsn: 1.243 ± 0.05
1.009ProPro: 1.009 ± 0.048
2.016ProGln: 2.016 ± 0.067
2.289ProArg: 2.289 ± 0.067
3.084ProSer: 3.084 ± 0.089
2.48ProThr: 2.48 ± 0.081
3.914ProVal: 3.914 ± 0.086
0.557ProTrp: 0.557 ± 0.036
1.345ProTyr: 1.345 ± 0.049
0.0ProXaa: 0.0 ± 0.0
Gln
3.919GlnAla: 3.919 ± 0.106
0.237GlnCys: 0.237 ± 0.023
1.75GlnAsp: 1.75 ± 0.061
1.937GlnGlu: 1.937 ± 0.067
1.216GlnPhe: 1.216 ± 0.047
2.387GlnGly: 2.387 ± 0.063
0.827GlnHis: 0.827 ± 0.04
2.059GlnIle: 2.059 ± 0.069
1.861GlnLys: 1.861 ± 0.069
3.498GlnLeu: 3.498 ± 0.078
1.062GlnMet: 1.062 ± 0.045
1.727GlnAsn: 1.727 ± 0.063
1.559GlnPro: 1.559 ± 0.066
1.603GlnGln: 1.603 ± 0.073
2.316GlnArg: 2.316 ± 0.067
2.261GlnSer: 2.261 ± 0.076
2.432GlnThr: 2.432 ± 0.073
2.361GlnVal: 2.361 ± 0.059
0.612GlnTrp: 0.612 ± 0.042
1.252GlnTyr: 1.252 ± 0.045
0.0GlnXaa: 0.0 ± 0.0
Arg
5.925ArgAla: 5.925 ± 0.123
0.359ArgCys: 0.359 ± 0.028
3.261ArgAsp: 3.261 ± 0.091
4.257ArgGlu: 4.257 ± 0.098
2.046ArgPhe: 2.046 ± 0.065
3.828ArgGly: 3.828 ± 0.085
1.227ArgHis: 1.227 ± 0.047
3.552ArgIle: 3.552 ± 0.081
2.195ArgLys: 2.195 ± 0.07
4.435ArgLeu: 4.435 ± 0.099
1.686ArgMet: 1.686 ± 0.049
1.589ArgAsn: 1.589 ± 0.064
1.987ArgPro: 1.987 ± 0.074
1.848ArgGln: 1.848 ± 0.059
3.586ArgArg: 3.586 ± 0.11
3.516ArgSer: 3.516 ± 0.09
3.646ArgThr: 3.646 ± 0.082
4.827ArgVal: 4.827 ± 0.105
0.748ArgTrp: 0.748 ± 0.038
1.773ArgTyr: 1.773 ± 0.051
0.0ArgXaa: 0.0 ± 0.0
Ser
7.794SerAla: 7.794 ± 0.145
0.441SerCys: 0.441 ± 0.036
3.787SerAsp: 3.787 ± 0.11
4.073SerGlu: 4.073 ± 0.092
2.568SerPhe: 2.568 ± 0.071
5.843SerGly: 5.843 ± 0.128
1.468SerHis: 1.468 ± 0.051
3.709SerIle: 3.709 ± 0.104
1.903SerLys: 1.903 ± 0.056
5.925SerLeu: 5.925 ± 0.099
1.739SerMet: 1.739 ± 0.059
1.673SerAsn: 1.673 ± 0.065
2.52SerPro: 2.52 ± 0.064
2.575SerGln: 2.575 ± 0.079
3.736SerArg: 3.736 ± 0.104
5.593SerSer: 5.593 ± 0.182
4.534SerThr: 4.534 ± 0.103
5.696SerVal: 5.696 ± 0.121
0.941SerTrp: 0.941 ± 0.039
1.882SerTyr: 1.882 ± 0.062
0.0SerXaa: 0.0 ± 0.0
Thr
6.648ThrAla: 6.648 ± 0.132
0.495ThrCys: 0.495 ± 0.028
3.703ThrAsp: 3.703 ± 0.091
3.262ThrGlu: 3.262 ± 0.079
2.35ThrPhe: 2.35 ± 0.065
4.927ThrGly: 4.927 ± 0.11
1.518ThrHis: 1.518 ± 0.064
3.382ThrIle: 3.382 ± 0.092
2.12ThrLys: 2.12 ± 0.062
6.153ThrLeu: 6.153 ± 0.143
1.352ThrMet: 1.352 ± 0.05
2.2ThrAsn: 2.2 ± 0.08
3.377ThrPro: 3.377 ± 0.08
2.402ThrGln: 2.402 ± 0.08
3.6ThrArg: 3.6 ± 0.089
4.482ThrSer: 4.482 ± 0.096
4.05ThrThr: 4.05 ± 0.099
5.696ThrVal: 5.696 ± 0.16
0.859ThrTrp: 0.859 ± 0.043
1.975ThrTyr: 1.975 ± 0.07
0.0ThrXaa: 0.0 ± 0.0
Val
8.039ValAla: 8.039 ± 0.17
0.721ValCys: 0.721 ± 0.038
4.98ValAsp: 4.98 ± 0.105
4.794ValGlu: 4.794 ± 0.121
2.737ValPhe: 2.737 ± 0.09
5.334ValGly: 5.334 ± 0.117
1.771ValHis: 1.771 ± 0.063
4.25ValIle: 4.25 ± 0.101
3.014ValLys: 3.014 ± 0.089
7.639ValLeu: 7.639 ± 0.127
1.712ValMet: 1.712 ± 0.059
2.646ValAsn: 2.646 ± 0.076
3.803ValPro: 3.803 ± 0.107
2.984ValGln: 2.984 ± 0.08
4.537ValArg: 4.537 ± 0.098
5.771ValSer: 5.771 ± 0.104
5.418ValThr: 5.418 ± 0.158
6.401ValVal: 6.401 ± 0.136
1.025ValTrp: 1.025 ± 0.045
2.216ValTyr: 2.216 ± 0.064
0.0ValXaa: 0.0 ± 0.0
Trp
1.136TrpAla: 1.136 ± 0.05
0.114TrpCys: 0.114 ± 0.015
0.818TrpAsp: 0.818 ± 0.039
0.666TrpGlu: 0.666 ± 0.035
0.507TrpPhe: 0.507 ± 0.034
0.889TrpGly: 0.889 ± 0.04
0.268TrpHis: 0.268 ± 0.024
0.695TrpIle: 0.695 ± 0.04
0.582TrpLys: 0.582 ± 0.033
1.345TrpLeu: 1.345 ± 0.059
0.418TrpMet: 0.418 ± 0.026
0.629TrpAsn: 0.629 ± 0.037
0.387TrpPro: 0.387 ± 0.027
0.562TrpGln: 0.562 ± 0.037
0.804TrpArg: 0.804 ± 0.037
0.886TrpSer: 0.886 ± 0.045
0.896TrpThr: 0.896 ± 0.043
0.854TrpVal: 0.854 ± 0.037
0.261TrpTrp: 0.261 ± 0.024
0.412TrpTyr: 0.412 ± 0.027
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.405TyrAla: 3.405 ± 0.082
0.236TyrCys: 0.236 ± 0.02
1.861TyrAsp: 1.861 ± 0.053
1.971TyrGlu: 1.971 ± 0.058
1.054TyrPhe: 1.054 ± 0.047
2.548TyrGly: 2.548 ± 0.071
0.568TyrHis: 0.568 ± 0.036
1.443TyrIle: 1.443 ± 0.048
0.957TyrLys: 0.957 ± 0.043
2.398TyrLeu: 2.398 ± 0.072
0.7TyrMet: 0.7 ± 0.034
0.952TyrAsn: 0.952 ± 0.051
1.329TyrPro: 1.329 ± 0.047
0.87TyrGln: 0.87 ± 0.04
1.55TyrArg: 1.55 ± 0.056
1.909TyrSer: 1.909 ± 0.06
2.211TyrThr: 2.211 ± 0.081
2.337TyrVal: 2.337 ± 0.073
0.354TyrTrp: 0.354 ± 0.025
0.88TyrTyr: 0.88 ± 0.042
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.002XaaLeu: 0.002 ± 0.002
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.002XaaTrp: 0.002 ± 0.002
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1550 proteins (560029 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski