Amino acid dipepetide frequency for Dolphin morbillivirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.279AlaAla: 3.279 ± 0.523
1.025AlaCys: 1.025 ± 0.398
2.46AlaAsp: 2.46 ± 0.524
3.074AlaGlu: 3.074 ± 1.529
1.64AlaPhe: 1.64 ± 0.447
4.714AlaGly: 4.714 ± 1.425
1.23AlaHis: 1.23 ± 0.589
3.484AlaIle: 3.484 ± 0.912
3.484AlaLys: 3.484 ± 0.764
6.969AlaLeu: 6.969 ± 1.365
1.23AlaMet: 1.23 ± 0.51
2.664AlaAsn: 2.664 ± 0.956
2.05AlaPro: 2.05 ± 0.928
1.845AlaGln: 1.845 ± 0.55
3.689AlaArg: 3.689 ± 1.153
3.689AlaSer: 3.689 ± 1.084
2.869AlaThr: 2.869 ± 0.665
5.329AlaVal: 5.329 ± 0.704
0.41AlaTrp: 0.41 ± 0.252
2.869AlaTyr: 2.869 ± 0.444
0.0AlaXaa: 0.0 ± 0.0
Cys
1.23CysAla: 1.23 ± 0.85
0.41CysCys: 0.41 ± 0.205
0.41CysAsp: 0.41 ± 0.239
1.025CysGlu: 1.025 ± 0.348
0.82CysPhe: 0.82 ± 0.31
0.82CysGly: 0.82 ± 0.514
0.205CysHis: 0.205 ± 0.266
0.41CysIle: 0.41 ± 0.257
1.025CysLys: 1.025 ± 0.549
0.82CysLeu: 0.82 ± 0.329
0.41CysMet: 0.41 ± 0.226
1.23CysAsn: 1.23 ± 0.48
0.615CysPro: 0.615 ± 0.246
0.615CysGln: 0.615 ± 0.385
0.82CysArg: 0.82 ± 0.41
1.845CysSer: 1.845 ± 0.433
0.82CysThr: 0.82 ± 0.359
1.23CysVal: 1.23 ± 0.445
0.0CysTrp: 0.0 ± 0.0
2.255CysTyr: 2.255 ± 0.458
0.0CysXaa: 0.0 ± 0.0
Asp
2.255AspAla: 2.255 ± 0.969
0.615AspCys: 0.615 ± 0.385
4.099AspAsp: 4.099 ± 1.107
3.689AspGlu: 3.689 ± 0.797
1.64AspPhe: 1.64 ± 0.699
1.64AspGly: 1.64 ± 0.442
1.23AspHis: 1.23 ± 0.613
4.304AspIle: 4.304 ± 0.894
2.05AspLys: 2.05 ± 0.764
7.174AspLeu: 7.174 ± 1.17
0.41AspMet: 0.41 ± 0.226
3.484AspAsn: 3.484 ± 0.44
4.099AspPro: 4.099 ± 0.997
1.845AspGln: 1.845 ± 0.467
3.484AspArg: 3.484 ± 0.867
3.074AspSer: 3.074 ± 0.399
2.869AspThr: 2.869 ± 0.954
3.484AspVal: 3.484 ± 0.744
0.82AspTrp: 0.82 ± 0.453
1.435AspTyr: 1.435 ± 0.463
0.0AspXaa: 0.0 ± 0.0
Glu
2.869GluAla: 2.869 ± 0.704
1.435GluCys: 1.435 ± 0.482
2.869GluAsp: 2.869 ± 0.71
3.074GluGlu: 3.074 ± 0.729
2.255GluPhe: 2.255 ± 0.965
3.279GluGly: 3.279 ± 0.462
1.23GluHis: 1.23 ± 0.474
5.329GluIle: 5.329 ± 0.502
3.279GluLys: 3.279 ± 0.519
4.919GluLeu: 4.919 ± 0.741
1.435GluMet: 1.435 ± 0.491
2.46GluAsn: 2.46 ± 0.901
3.074GluPro: 3.074 ± 1.04
0.615GluGln: 0.615 ± 0.294
2.255GluArg: 2.255 ± 0.816
6.149GluSer: 6.149 ± 1.92
4.714GluThr: 4.714 ± 1.031
4.919GluVal: 4.919 ± 0.524
0.82GluTrp: 0.82 ± 0.334
1.435GluTyr: 1.435 ± 0.405
0.0GluXaa: 0.0 ± 0.0
Phe
1.435PheAla: 1.435 ± 0.365
0.41PheCys: 0.41 ± 0.226
1.64PheAsp: 1.64 ± 0.187
1.64PheGlu: 1.64 ± 0.644
1.64PhePhe: 1.64 ± 0.791
2.46PheGly: 2.46 ± 0.433
0.615PheHis: 0.615 ± 0.385
3.074PheIle: 3.074 ± 0.848
2.46PheLys: 2.46 ± 0.737
3.689PheLeu: 3.689 ± 0.76
1.845PheMet: 1.845 ± 0.766
1.435PheAsn: 1.435 ± 0.383
0.82PhePro: 0.82 ± 0.739
0.615PheGln: 0.615 ± 0.336
2.664PheArg: 2.664 ± 1.064
1.64PheSer: 1.64 ± 0.714
1.025PheThr: 1.025 ± 0.436
2.05PheVal: 2.05 ± 0.665
0.41PheTrp: 0.41 ± 0.257
0.82PheTyr: 0.82 ± 0.329
0.0PheXaa: 0.0 ± 0.0
Gly
2.869GlyAla: 2.869 ± 0.454
0.615GlyCys: 0.615 ± 0.308
3.894GlyAsp: 3.894 ± 0.993
3.689GlyGlu: 3.689 ± 1.107
2.664GlyPhe: 2.664 ± 0.907
4.099GlyGly: 4.099 ± 0.844
1.23GlyHis: 1.23 ± 0.583
5.124GlyIle: 5.124 ± 0.849
2.46GlyLys: 2.46 ± 0.532
7.993GlyLeu: 7.993 ± 0.97
1.64GlyMet: 1.64 ± 0.514
2.46GlyAsn: 2.46 ± 0.724
2.46GlyPro: 2.46 ± 0.618
2.05GlyGln: 2.05 ± 0.403
2.255GlyArg: 2.255 ± 0.72
5.534GlySer: 5.534 ± 0.837
3.074GlyThr: 3.074 ± 1.345
4.509GlyVal: 4.509 ± 1.376
0.41GlyTrp: 0.41 ± 0.239
3.074GlyTyr: 3.074 ± 0.751
0.0GlyXaa: 0.0 ± 0.0
His
1.64HisAla: 1.64 ± 0.501
0.82HisCys: 0.82 ± 0.334
1.23HisAsp: 1.23 ± 0.771
1.23HisGlu: 1.23 ± 0.589
0.41HisPhe: 0.41 ± 0.257
1.435HisGly: 1.435 ± 0.492
1.23HisHis: 1.23 ± 0.409
1.025HisIle: 1.025 ± 0.508
0.82HisLys: 0.82 ± 0.297
1.845HisLeu: 1.845 ± 0.982
0.41HisMet: 0.41 ± 0.257
0.615HisAsn: 0.615 ± 0.291
1.025HisPro: 1.025 ± 0.358
1.64HisGln: 1.64 ± 0.705
1.845HisArg: 1.845 ± 0.915
0.82HisSer: 0.82 ± 0.244
0.615HisThr: 0.615 ± 0.254
1.845HisVal: 1.845 ± 0.453
0.615HisTrp: 0.615 ± 0.431
0.41HisTyr: 0.41 ± 0.226
0.0HisXaa: 0.0 ± 0.0
Ile
4.714IleAla: 4.714 ± 0.827
0.41IleCys: 0.41 ± 0.331
2.869IleAsp: 2.869 ± 0.896
4.714IleGlu: 4.714 ± 0.851
1.845IlePhe: 1.845 ± 0.476
5.329IleGly: 5.329 ± 0.798
1.845IleHis: 1.845 ± 0.527
6.764IleIle: 6.764 ± 1.501
6.969IleLys: 6.969 ± 1.079
7.993IleLeu: 7.993 ± 1.706
1.64IleMet: 1.64 ± 0.572
4.714IleAsn: 4.714 ± 1.186
3.279IlePro: 3.279 ± 0.673
2.46IleGln: 2.46 ± 1.322
4.304IleArg: 4.304 ± 0.499
7.584IleSer: 7.584 ± 1.496
4.919IleThr: 4.919 ± 0.42
4.099IleVal: 4.099 ± 0.982
0.205IleTrp: 0.205 ± 0.259
2.869IleTyr: 2.869 ± 1.157
0.0IleXaa: 0.0 ± 0.0
Lys
2.664LysAla: 2.664 ± 0.491
1.025LysCys: 1.025 ± 0.656
4.919LysAsp: 4.919 ± 1.302
4.099LysGlu: 4.099 ± 0.928
1.23LysPhe: 1.23 ± 0.59
3.689LysGly: 3.689 ± 0.685
0.615LysHis: 0.615 ± 0.294
4.304LysIle: 4.304 ± 0.869
3.074LysLys: 3.074 ± 1.045
6.149LysLeu: 6.149 ± 1.723
2.46LysMet: 2.46 ± 0.932
2.46LysAsn: 2.46 ± 0.589
2.46LysPro: 2.46 ± 0.876
1.23LysGln: 1.23 ± 0.482
3.894LysArg: 3.894 ± 0.904
4.304LysSer: 4.304 ± 1.057
1.435LysThr: 1.435 ± 0.633
3.484LysVal: 3.484 ± 0.698
0.0LysTrp: 0.0 ± 0.0
2.46LysTyr: 2.46 ± 1.087
0.0LysXaa: 0.0 ± 0.0
Leu
7.993LeuAla: 7.993 ± 1.374
1.845LeuCys: 1.845 ± 0.446
6.764LeuAsp: 6.764 ± 0.614
7.379LeuGlu: 7.379 ± 1.021
3.279LeuPhe: 3.279 ± 1.014
6.764LeuGly: 6.764 ± 1.406
2.46LeuHis: 2.46 ± 0.542
7.788LeuIle: 7.788 ± 1.686
5.944LeuLys: 5.944 ± 1.426
9.223LeuLeu: 9.223 ± 0.99
2.46LeuMet: 2.46 ± 0.792
3.484LeuAsn: 3.484 ± 0.798
2.664LeuPro: 2.664 ± 0.61
2.46LeuGln: 2.46 ± 0.621
5.739LeuArg: 5.739 ± 0.92
7.993LeuSer: 7.993 ± 1.692
7.788LeuThr: 7.788 ± 0.972
7.788LeuVal: 7.788 ± 1.075
1.025LeuTrp: 1.025 ± 0.333
2.664LeuTyr: 2.664 ± 0.947
0.0LeuXaa: 0.0 ± 0.0
Met
1.23MetAla: 1.23 ± 0.454
0.205MetCys: 0.205 ± 0.128
0.82MetAsp: 0.82 ± 0.31
0.82MetGlu: 0.82 ± 0.304
0.615MetPhe: 0.615 ± 0.336
1.435MetGly: 1.435 ± 0.734
0.205MetHis: 0.205 ± 0.238
3.689MetIle: 3.689 ± 0.598
1.845MetLys: 1.845 ± 0.639
2.46MetLeu: 2.46 ± 0.719
0.82MetMet: 0.82 ± 0.551
0.82MetAsn: 0.82 ± 0.329
1.025MetPro: 1.025 ± 0.29
0.615MetGln: 0.615 ± 0.336
1.025MetArg: 1.025 ± 0.378
3.074MetSer: 3.074 ± 1.086
2.255MetThr: 2.255 ± 0.601
1.64MetVal: 1.64 ± 0.875
0.205MetTrp: 0.205 ± 0.128
1.435MetTyr: 1.435 ± 0.436
0.0MetXaa: 0.0 ± 0.0
Asn
2.255AsnAla: 2.255 ± 0.832
1.23AsnCys: 1.23 ± 0.412
2.05AsnAsp: 2.05 ± 0.63
2.664AsnGlu: 2.664 ± 0.686
2.05AsnPhe: 2.05 ± 0.6
2.664AsnGly: 2.664 ± 0.799
0.82AsnHis: 0.82 ± 0.692
3.074AsnIle: 3.074 ± 0.599
2.869AsnLys: 2.869 ± 0.774
5.739AsnLeu: 5.739 ± 1.076
1.025AsnMet: 1.025 ± 0.306
1.435AsnAsn: 1.435 ± 0.262
2.05AsnPro: 2.05 ± 0.645
3.074AsnGln: 3.074 ± 0.284
2.255AsnArg: 2.255 ± 0.666
3.894AsnSer: 3.894 ± 0.59
1.64AsnThr: 1.64 ± 0.68
1.64AsnVal: 1.64 ± 0.555
0.615AsnTrp: 0.615 ± 0.385
1.845AsnTyr: 1.845 ± 0.915
0.0AsnXaa: 0.0 ± 0.0
Pro
2.46ProAla: 2.46 ± 0.966
0.205ProCys: 0.205 ± 0.128
3.074ProAsp: 3.074 ± 0.974
2.05ProGlu: 2.05 ± 0.373
1.025ProPhe: 1.025 ± 0.698
3.279ProGly: 3.279 ± 0.832
0.41ProHis: 0.41 ± 0.226
3.689ProIle: 3.689 ± 0.87
3.689ProLys: 3.689 ± 0.74
3.894ProLeu: 3.894 ± 1.429
1.025ProMet: 1.025 ± 0.388
1.435ProAsn: 1.435 ± 0.579
3.279ProPro: 3.279 ± 1.362
1.23ProGln: 1.23 ± 1.065
3.074ProArg: 3.074 ± 0.628
3.894ProSer: 3.894 ± 0.62
2.46ProThr: 2.46 ± 0.784
2.255ProVal: 2.255 ± 0.585
0.615ProTrp: 0.615 ± 0.318
2.05ProTyr: 2.05 ± 0.808
0.0ProXaa: 0.0 ± 0.0
Gln
3.074GlnAla: 3.074 ± 1.125
0.615GlnCys: 0.615 ± 0.246
2.05GlnAsp: 2.05 ± 0.54
1.64GlnGlu: 1.64 ± 0.725
0.41GlnPhe: 0.41 ± 0.226
2.05GlnGly: 2.05 ± 0.483
0.205GlnHis: 0.205 ± 0.128
3.074GlnIle: 3.074 ± 0.949
2.255GlnLys: 2.255 ± 0.871
2.664GlnLeu: 2.664 ± 0.364
1.23GlnMet: 1.23 ± 0.249
1.64GlnAsn: 1.64 ± 0.625
0.615GlnPro: 0.615 ± 0.308
2.255GlnGln: 2.255 ± 0.628
1.64GlnArg: 1.64 ± 0.632
3.279GlnSer: 3.279 ± 0.656
1.64GlnThr: 1.64 ± 0.359
1.64GlnVal: 1.64 ± 0.511
0.41GlnTrp: 0.41 ± 0.257
0.615GlnTyr: 0.615 ± 0.498
0.0GlnXaa: 0.0 ± 0.0
Arg
3.074ArgAla: 3.074 ± 0.99
1.025ArgCys: 1.025 ± 0.391
2.664ArgAsp: 2.664 ± 0.772
2.869ArgGlu: 2.869 ± 0.899
1.64ArgPhe: 1.64 ± 0.391
4.304ArgGly: 4.304 ± 0.954
1.64ArgHis: 1.64 ± 0.804
3.689ArgIle: 3.689 ± 1.047
2.46ArgLys: 2.46 ± 0.715
6.969ArgLeu: 6.969 ± 1.809
1.64ArgMet: 1.64 ± 0.395
2.46ArgAsn: 2.46 ± 0.599
2.664ArgPro: 2.664 ± 1.185
1.435ArgGln: 1.435 ± 0.314
3.074ArgArg: 3.074 ± 0.98
6.559ArgSer: 6.559 ± 1.253
2.664ArgThr: 2.664 ± 0.737
4.099ArgVal: 4.099 ± 1.045
0.615ArgTrp: 0.615 ± 0.396
2.05ArgTyr: 2.05 ± 0.88
0.0ArgXaa: 0.0 ± 0.0
Ser
4.509SerAla: 4.509 ± 1.317
1.845SerCys: 1.845 ± 0.694
3.689SerAsp: 3.689 ± 0.896
4.509SerGlu: 4.509 ± 1.354
2.869SerPhe: 2.869 ± 0.702
5.534SerGly: 5.534 ± 0.787
2.05SerHis: 2.05 ± 0.85
7.788SerIle: 7.788 ± 1.216
3.689SerLys: 3.689 ± 0.533
8.813SerLeu: 8.813 ± 1.284
2.664SerMet: 2.664 ± 0.734
4.714SerAsn: 4.714 ± 1.507
2.46SerPro: 2.46 ± 0.486
3.894SerGln: 3.894 ± 1.141
5.739SerArg: 5.739 ± 1.022
7.788SerSer: 7.788 ± 2.153
5.124SerThr: 5.124 ± 0.945
3.689SerVal: 3.689 ± 0.863
0.82SerTrp: 0.82 ± 0.399
2.255SerTyr: 2.255 ± 0.931
0.0SerXaa: 0.0 ± 0.0
Thr
5.739ThrAla: 5.739 ± 1.131
0.205ThrCys: 0.205 ± 0.271
1.64ThrAsp: 1.64 ± 0.602
3.894ThrGlu: 3.894 ± 0.752
1.845ThrPhe: 1.845 ± 0.555
3.279ThrGly: 3.279 ± 0.931
1.23ThrHis: 1.23 ± 0.378
5.124ThrIle: 5.124 ± 0.89
2.869ThrLys: 2.869 ± 0.715
4.509ThrLeu: 4.509 ± 0.521
1.025ThrMet: 1.025 ± 0.351
2.869ThrAsn: 2.869 ± 0.646
3.279ThrPro: 3.279 ± 1.037
1.64ThrGln: 1.64 ± 0.405
3.484ThrArg: 3.484 ± 0.784
4.509ThrSer: 4.509 ± 0.618
3.894ThrThr: 3.894 ± 0.704
3.484ThrVal: 3.484 ± 0.603
0.615ThrTrp: 0.615 ± 0.385
2.46ThrTyr: 2.46 ± 0.52
0.0ThrXaa: 0.0 ± 0.0
Val
2.664ValAla: 2.664 ± 0.973
1.025ValCys: 1.025 ± 0.304
3.279ValAsp: 3.279 ± 0.823
4.714ValGlu: 4.714 ± 1.539
1.435ValPhe: 1.435 ± 0.795
3.279ValGly: 3.279 ± 1.516
1.435ValHis: 1.435 ± 0.534
4.714ValIle: 4.714 ± 1.323
3.279ValLys: 3.279 ± 0.581
6.559ValLeu: 6.559 ± 1.322
1.435ValMet: 1.435 ± 0.794
2.664ValAsn: 2.664 ± 0.68
3.279ValPro: 3.279 ± 0.771
2.05ValGln: 2.05 ± 0.574
4.099ValArg: 4.099 ± 0.679
4.509ValSer: 4.509 ± 0.842
5.739ValThr: 5.739 ± 0.775
3.484ValVal: 3.484 ± 0.977
0.0ValTrp: 0.0 ± 0.0
2.869ValTyr: 2.869 ± 0.628
0.0ValXaa: 0.0 ± 0.0
Trp
1.025TrpAla: 1.025 ± 0.496
0.41TrpCys: 0.41 ± 0.532
0.615TrpAsp: 0.615 ± 0.308
0.205TrpGlu: 0.205 ± 0.266
1.23TrpPhe: 1.23 ± 0.467
0.41TrpGly: 0.41 ± 0.205
0.205TrpHis: 0.205 ± 0.128
0.41TrpIle: 0.41 ± 0.517
0.205TrpLys: 0.205 ± 0.256
0.82TrpLeu: 0.82 ± 0.272
0.0TrpMet: 0.0 ± 0.0
0.41TrpAsn: 0.41 ± 0.257
0.41TrpPro: 0.41 ± 0.257
0.0TrpGln: 0.0 ± 0.0
0.615TrpArg: 0.615 ± 0.308
1.025TrpSer: 1.025 ± 0.457
0.41TrpThr: 0.41 ± 0.257
0.205TrpVal: 0.205 ± 0.128
0.205TrpTrp: 0.205 ± 0.128
0.41TrpTyr: 0.41 ± 0.205
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.025TyrAla: 1.025 ± 0.538
1.64TyrCys: 1.64 ± 0.447
2.664TyrAsp: 2.664 ± 0.68
1.435TyrGlu: 1.435 ± 0.439
1.845TyrPhe: 1.845 ± 0.701
1.64TyrGly: 1.64 ± 0.666
1.435TyrHis: 1.435 ± 0.672
2.664TyrIle: 2.664 ± 0.29
1.23TyrLys: 1.23 ± 0.445
4.509TyrLeu: 4.509 ± 1.711
1.23TyrMet: 1.23 ± 0.546
1.435TyrAsn: 1.435 ± 0.365
3.484TyrPro: 3.484 ± 0.626
1.435TyrGln: 1.435 ± 0.355
1.64TyrArg: 1.64 ± 0.496
3.279TyrSer: 3.279 ± 1.42
1.64TyrThr: 1.64 ± 0.34
1.64TyrVal: 1.64 ± 0.947
0.41TyrTrp: 0.41 ± 0.257
1.025TyrTyr: 1.025 ± 0.29
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (4880 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski