Amino acid dipepetide frequency for Maize streak Reunion virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.762AlaAla: 4.762 ± 2.073
0.0AlaCys: 0.0 ± 0.0
0.952AlaAsp: 0.952 ± 1.252
6.667AlaGlu: 6.667 ± 2.795
5.714AlaPhe: 5.714 ± 2.226
8.571AlaGly: 8.571 ± 0.468
0.0AlaHis: 0.0 ± 0.0
0.0AlaIle: 0.0 ± 0.0
2.857AlaLys: 2.857 ± 1.346
2.857AlaLeu: 2.857 ± 2.187
0.0AlaMet: 0.0 ± 0.0
1.905AlaAsn: 1.905 ± 0.742
3.81AlaPro: 3.81 ± 2.532
2.857AlaGln: 2.857 ± 1.599
6.667AlaArg: 6.667 ± 1.944
5.714AlaSer: 5.714 ± 2.796
2.857AlaThr: 2.857 ± 1.194
0.0AlaVal: 0.0 ± 0.0
1.905AlaTrp: 1.905 ± 1.781
1.905AlaTyr: 1.905 ± 1.781
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.952CysGly: 0.952 ± 0.89
0.952CysHis: 0.952 ± 0.89
0.0CysIle: 0.0 ± 0.0
0.952CysLys: 0.952 ± 0.89
2.857CysLeu: 2.857 ± 1.097
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.952CysPro: 0.952 ± 0.708
0.952CysGln: 0.952 ± 0.823
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.952CysThr: 0.952 ± 0.823
0.952CysVal: 0.952 ± 0.708
0.952CysTrp: 0.952 ± 0.708
1.905CysTyr: 1.905 ± 0.742
0.0CysXaa: 0.0 ± 0.0
Asp
0.952AspAla: 0.952 ± 0.708
0.0AspCys: 0.0 ± 0.0
2.857AspAsp: 2.857 ± 1.194
6.667AspGlu: 6.667 ± 1.601
0.952AspPhe: 0.952 ± 0.708
2.857AspGly: 2.857 ± 1.097
0.0AspHis: 0.0 ± 0.0
3.81AspIle: 3.81 ± 0.729
0.0AspLys: 0.0 ± 0.0
4.762AspLeu: 4.762 ± 0.859
0.0AspMet: 0.0 ± 0.0
0.952AspAsn: 0.952 ± 0.708
5.714AspPro: 5.714 ± 1.636
0.952AspGln: 0.952 ± 0.823
0.952AspArg: 0.952 ± 1.252
1.905AspSer: 1.905 ± 1.781
2.857AspThr: 2.857 ± 0.463
0.952AspVal: 0.952 ± 1.252
0.952AspTrp: 0.952 ± 0.708
2.857AspTyr: 2.857 ± 1.194
0.0AspXaa: 0.0 ± 0.0
Glu
2.857GluAla: 2.857 ± 1.097
0.952GluCys: 0.952 ± 0.823
3.81GluAsp: 3.81 ± 0.729
1.905GluGlu: 1.905 ± 0.742
0.952GluPhe: 0.952 ± 0.89
0.0GluGly: 0.0 ± 0.0
0.952GluHis: 0.952 ± 0.823
1.905GluIle: 1.905 ± 0.742
0.952GluLys: 0.952 ± 0.708
0.952GluLeu: 0.952 ± 0.708
0.0GluMet: 0.0 ± 0.0
2.857GluAsn: 2.857 ± 0.463
1.905GluPro: 1.905 ± 0.742
1.905GluGln: 1.905 ± 0.948
1.905GluArg: 1.905 ± 0.742
3.81GluSer: 3.81 ± 1.024
4.762GluThr: 4.762 ± 0.859
8.571GluVal: 8.571 ± 1.363
2.857GluTrp: 2.857 ± 0.463
7.619GluTyr: 7.619 ± 2.211
0.0GluXaa: 0.0 ± 0.0
Phe
1.905PheAla: 1.905 ± 1.781
0.952PheCys: 0.952 ± 0.708
1.905PheAsp: 1.905 ± 0.742
5.714PheGlu: 5.714 ± 2.226
1.905PhePhe: 1.905 ± 0.742
3.81PheGly: 3.81 ± 0.943
0.952PheHis: 0.952 ± 0.89
2.857PheIle: 2.857 ± 1.097
3.81PheLys: 3.81 ± 0.729
2.857PheLeu: 2.857 ± 1.194
0.0PheMet: 0.0 ± 0.0
0.952PheAsn: 0.952 ± 0.89
4.762PhePro: 4.762 ± 1.393
3.81PheGln: 3.81 ± 1.484
0.952PheArg: 0.952 ± 1.252
0.952PheSer: 0.952 ± 0.89
0.952PheThr: 0.952 ± 0.89
5.714PheVal: 5.714 ± 0.705
0.0PheTrp: 0.0 ± 0.0
1.905PheTyr: 1.905 ± 1.415
0.0PheXaa: 0.0 ± 0.0
Gly
5.714GlyAla: 5.714 ± 1.829
0.0GlyCys: 0.0 ± 0.0
2.857GlyAsp: 2.857 ± 1.346
0.0GlyGlu: 0.0 ± 0.0
3.81GlyPhe: 3.81 ± 2.235
2.857GlyGly: 2.857 ± 1.596
0.0GlyHis: 0.0 ± 0.0
4.762GlyIle: 4.762 ± 0.833
1.905GlyLys: 1.905 ± 0.858
2.857GlyLeu: 2.857 ± 1.645
0.952GlyMet: 0.952 ± 0.823
5.714GlyAsn: 5.714 ± 2.239
4.762GlyPro: 4.762 ± 1.393
2.857GlyGln: 2.857 ± 1.194
1.905GlyArg: 1.905 ± 1.543
7.619GlySer: 7.619 ± 2.419
8.571GlyThr: 8.571 ± 0.468
3.81GlyVal: 3.81 ± 2.441
0.0GlyTrp: 0.0 ± 0.0
4.762GlyTyr: 4.762 ± 0.859
0.0GlyXaa: 0.0 ± 0.0
His
1.905HisAla: 1.905 ± 1.646
0.952HisCys: 0.952 ± 0.823
1.905HisAsp: 1.905 ± 0.742
0.952HisGlu: 0.952 ± 0.708
2.857HisPhe: 2.857 ± 0.463
0.952HisGly: 0.952 ± 1.252
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.952HisLys: 0.952 ± 0.89
4.762HisLeu: 4.762 ± 0.859
0.0HisMet: 0.0 ± 0.0
0.952HisAsn: 0.952 ± 0.708
5.714HisPro: 5.714 ± 2.796
1.905HisGln: 1.905 ± 0.742
0.952HisArg: 0.952 ± 0.89
0.0HisSer: 0.0 ± 0.0
0.952HisThr: 0.952 ± 0.89
1.905HisVal: 1.905 ± 0.742
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.857IleAla: 2.857 ± 2.187
0.952IleCys: 0.952 ± 1.252
0.952IleAsp: 0.952 ± 0.708
1.905IleGlu: 1.905 ± 0.742
2.857IlePhe: 2.857 ± 0.463
2.857IleGly: 2.857 ± 2.187
0.952IleHis: 0.952 ± 1.252
3.81IleIle: 3.81 ± 1.251
0.952IleLys: 0.952 ± 0.89
5.714IleLeu: 5.714 ± 1.636
1.905IleMet: 1.905 ± 0.742
0.0IleAsn: 0.0 ± 0.0
3.81IlePro: 3.81 ± 1.817
4.762IleGln: 4.762 ± 0.859
4.762IleArg: 4.762 ± 1.393
0.0IleSer: 0.0 ± 0.0
3.81IleThr: 3.81 ± 1.21
1.905IleVal: 1.905 ± 1.248
0.0IleTrp: 0.0 ± 0.0
1.905IleTyr: 1.905 ± 0.948
0.0IleXaa: 0.0 ± 0.0
Lys
3.81LysAla: 3.81 ± 1.484
0.0LysCys: 0.0 ± 0.0
3.81LysAsp: 3.81 ± 0.729
0.0LysGlu: 0.0 ± 0.0
2.857LysPhe: 2.857 ± 1.296
1.905LysGly: 1.905 ± 1.781
0.0LysHis: 0.0 ± 0.0
0.952LysIle: 0.952 ± 0.89
0.952LysLys: 0.952 ± 0.89
1.905LysLeu: 1.905 ± 0.742
0.0LysMet: 0.0 ± 0.0
0.952LysAsn: 0.952 ± 0.89
0.0LysPro: 0.0 ± 0.0
1.905LysGln: 1.905 ± 0.858
6.667LysArg: 6.667 ± 3.075
5.714LysSer: 5.714 ± 1.195
4.762LysThr: 4.762 ± 1.105
1.905LysVal: 1.905 ± 0.858
0.952LysTrp: 0.952 ± 0.823
2.857LysTyr: 2.857 ± 2.123
0.0LysXaa: 0.0 ± 0.0
Leu
1.905LeuAla: 1.905 ± 0.742
0.0LeuCys: 0.0 ± 0.0
1.905LeuAsp: 1.905 ± 0.858
2.857LeuGlu: 2.857 ± 0.463
1.905LeuPhe: 1.905 ± 0.742
3.81LeuGly: 3.81 ± 1.979
5.714LeuHis: 5.714 ± 1.516
1.905LeuIle: 1.905 ± 1.543
5.714LeuLys: 5.714 ± 1.195
8.571LeuLeu: 8.571 ± 1.758
0.0LeuMet: 0.0 ± 0.0
0.0LeuAsn: 0.0 ± 0.0
4.762LeuPro: 4.762 ± 2.082
7.619LeuGln: 7.619 ± 1.098
0.952LeuArg: 0.952 ± 1.252
4.762LeuSer: 4.762 ± 2.168
5.714LeuThr: 5.714 ± 2.226
4.762LeuVal: 4.762 ± 2.438
2.857LeuTrp: 2.857 ± 0.463
3.81LeuTyr: 3.81 ± 2.441
0.0LeuXaa: 0.0 ± 0.0
Met
0.952MetAla: 0.952 ± 0.89
0.0MetCys: 0.0 ± 0.0
0.952MetAsp: 0.952 ± 0.823
2.857MetGlu: 2.857 ± 1.596
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.905MetLeu: 1.905 ± 1.646
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.905MetArg: 1.905 ± 0.742
3.81MetSer: 3.81 ± 1.484
1.905MetThr: 1.905 ± 0.858
0.952MetVal: 0.952 ± 0.89
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.905AsnAla: 1.905 ± 0.742
0.952AsnCys: 0.952 ± 0.708
1.905AsnAsp: 1.905 ± 1.781
1.905AsnGlu: 1.905 ± 0.742
1.905AsnPhe: 1.905 ± 0.742
4.762AsnGly: 4.762 ± 3.309
2.857AsnHis: 2.857 ± 1.194
4.762AsnIle: 4.762 ± 0.859
1.905AsnLys: 1.905 ± 0.742
0.0AsnLeu: 0.0 ± 0.0
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
2.857AsnPro: 2.857 ± 1.599
1.905AsnGln: 1.905 ± 1.781
0.0AsnArg: 0.0 ± 0.0
2.857AsnSer: 2.857 ± 2.671
0.952AsnThr: 0.952 ± 1.252
1.905AsnVal: 1.905 ± 0.858
0.0AsnTrp: 0.0 ± 0.0
1.905AsnTyr: 1.905 ± 1.415
0.0AsnXaa: 0.0 ± 0.0
Pro
2.857ProAla: 2.857 ± 2.398
1.905ProCys: 1.905 ± 0.858
3.81ProAsp: 3.81 ± 1.484
0.0ProGlu: 0.0 ± 0.0
6.667ProPhe: 6.667 ± 2.565
8.571ProGly: 8.571 ± 1.752
4.762ProHis: 4.762 ± 2.082
2.857ProIle: 2.857 ± 1.097
2.857ProLys: 2.857 ± 1.194
2.857ProLeu: 2.857 ± 1.097
1.905ProMet: 1.905 ± 0.742
4.762ProAsn: 4.762 ± 0.859
9.524ProPro: 9.524 ± 1.491
1.905ProGln: 1.905 ± 1.358
8.571ProArg: 8.571 ± 1.363
15.238ProSer: 15.238 ± 1.546
8.571ProThr: 8.571 ± 1.326
7.619ProVal: 7.619 ± 1.749
2.857ProTrp: 2.857 ± 1.097
1.905ProTyr: 1.905 ± 0.948
0.0ProXaa: 0.0 ± 0.0
Gln
4.762GlnAla: 4.762 ± 2.082
0.0GlnCys: 0.0 ± 0.0
2.857GlnAsp: 2.857 ± 1.398
0.0GlnGlu: 0.0 ± 0.0
3.81GlnPhe: 3.81 ± 1.484
4.762GlnGly: 4.762 ± 1.393
3.81GlnHis: 3.81 ± 1.484
0.952GlnIle: 0.952 ± 0.89
2.857GlnLys: 2.857 ± 1.194
1.905GlnLeu: 1.905 ± 1.415
2.857GlnMet: 2.857 ± 0.53
0.952GlnAsn: 0.952 ± 0.708
4.762GlnPro: 4.762 ± 3.786
1.905GlnGln: 1.905 ± 0.742
2.857GlnArg: 2.857 ± 2.187
1.905GlnSer: 1.905 ± 1.358
2.857GlnThr: 2.857 ± 0.463
1.905GlnVal: 1.905 ± 1.358
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.762ArgAla: 4.762 ± 2.365
1.905ArgCys: 1.905 ± 0.742
2.857ArgAsp: 2.857 ± 1.097
2.857ArgGlu: 2.857 ± 0.463
0.952ArgPhe: 0.952 ± 0.89
7.619ArgGly: 7.619 ± 1.108
0.952ArgHis: 0.952 ± 0.89
0.0ArgIle: 0.0 ± 0.0
1.905ArgLys: 1.905 ± 0.858
4.762ArgLeu: 4.762 ± 1.314
0.952ArgMet: 0.952 ± 0.708
6.667ArgAsn: 6.667 ± 1.601
5.714ArgPro: 5.714 ± 1.195
1.905ArgGln: 1.905 ± 2.505
5.714ArgArg: 5.714 ± 1.87
7.619ArgSer: 7.619 ± 1.362
3.81ArgThr: 3.81 ± 1.715
2.857ArgVal: 2.857 ± 2.187
0.952ArgTrp: 0.952 ± 1.252
0.952ArgTyr: 0.952 ± 0.89
0.0ArgXaa: 0.0 ± 0.0
Ser
8.571SerAla: 8.571 ± 1.363
0.0SerCys: 0.0 ± 0.0
2.857SerAsp: 2.857 ± 0.463
8.571SerGlu: 8.571 ± 2.255
0.0SerPhe: 0.0 ± 0.0
2.857SerGly: 2.857 ± 0.463
1.905SerHis: 1.905 ± 0.742
3.81SerIle: 3.81 ± 1.715
3.81SerLys: 3.81 ± 1.21
5.714SerLeu: 5.714 ± 1.421
0.952SerMet: 0.952 ± 0.896
2.857SerAsn: 2.857 ± 2.671
6.667SerPro: 6.667 ± 1.944
0.952SerGln: 0.952 ± 0.89
8.571SerArg: 8.571 ± 2.207
4.762SerSer: 4.762 ± 2.073
7.619SerThr: 7.619 ± 2.971
4.762SerVal: 4.762 ± 1.314
1.905SerTrp: 1.905 ± 0.742
2.857SerTyr: 2.857 ± 1.097
0.0SerXaa: 0.0 ± 0.0
Thr
1.905ThrAla: 1.905 ± 1.543
1.905ThrCys: 1.905 ± 0.742
0.952ThrAsp: 0.952 ± 1.252
1.905ThrGlu: 1.905 ± 1.543
2.857ThrPhe: 2.857 ± 0.463
1.905ThrGly: 1.905 ± 0.858
0.952ThrHis: 0.952 ± 0.89
4.762ThrIle: 4.762 ± 0.859
1.905ThrLys: 1.905 ± 0.742
4.762ThrLeu: 4.762 ± 1.47
0.952ThrMet: 0.952 ± 0.89
0.952ThrAsn: 0.952 ± 0.89
16.19ThrPro: 16.19 ± 5.325
1.905ThrGln: 1.905 ± 1.358
8.571ThrArg: 8.571 ± 1.363
7.619ThrSer: 7.619 ± 1.163
4.762ThrThr: 4.762 ± 1.858
2.857ThrVal: 2.857 ± 1.194
1.905ThrTrp: 1.905 ± 0.858
3.81ThrTyr: 3.81 ± 1.21
0.0ThrXaa: 0.0 ± 0.0
Val
3.81ValAla: 3.81 ± 1.21
0.952ValCys: 0.952 ± 0.89
0.952ValAsp: 0.952 ± 0.708
1.905ValGlu: 1.905 ± 0.948
1.905ValPhe: 1.905 ± 1.543
4.762ValGly: 4.762 ± 1.36
0.952ValHis: 0.952 ± 0.823
1.905ValIle: 1.905 ± 2.505
1.905ValLys: 1.905 ± 1.781
4.762ValLeu: 4.762 ± 0.833
1.905ValMet: 1.905 ± 1.144
2.857ValAsn: 2.857 ± 2.123
11.429ValPro: 11.429 ± 1.126
3.81ValGln: 3.81 ± 1.484
1.905ValArg: 1.905 ± 1.781
0.952ValSer: 0.952 ± 0.89
0.952ValThr: 0.952 ± 1.252
2.857ValVal: 2.857 ± 1.346
0.952ValTrp: 0.952 ± 0.89
4.762ValTyr: 4.762 ± 2.201
0.0ValXaa: 0.0 ± 0.0
Trp
2.857TrpAla: 2.857 ± 1.194
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.905TrpGlu: 1.905 ± 0.742
1.905TrpPhe: 1.905 ± 2.505
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
4.762TrpLys: 4.762 ± 1.105
1.905TrpLeu: 1.905 ± 0.858
0.952TrpMet: 0.952 ± 0.823
0.952TrpAsn: 0.952 ± 0.89
1.905TrpPro: 1.905 ± 1.781
0.952TrpGln: 0.952 ± 0.708
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
1.905TrpThr: 1.905 ± 0.742
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.952TyrAla: 0.952 ± 0.708
0.952TyrCys: 0.952 ± 0.89
2.857TyrAsp: 2.857 ± 1.296
2.857TyrGlu: 2.857 ± 0.463
2.857TyrPhe: 2.857 ± 1.599
1.905TyrGly: 1.905 ± 0.742
1.905TyrHis: 1.905 ± 0.742
7.619TyrIle: 7.619 ± 1.098
0.952TyrLys: 0.952 ± 0.89
2.857TyrLeu: 2.857 ± 1.097
0.952TyrMet: 0.952 ± 0.823
0.952TyrAsn: 0.952 ± 0.708
4.762TyrPro: 4.762 ± 1.393
0.952TyrGln: 0.952 ± 0.708
1.905TyrArg: 1.905 ± 1.248
5.714TyrSer: 5.714 ± 0.926
3.81TyrThr: 3.81 ± 1.715
0.0TyrVal: 0.0 ± 0.0
0.952TyrTrp: 0.952 ± 0.708
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1051 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski