Amino acid dipepetide frequency for Listeria phage A118 (Bacteriophage A118)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.339AlaAla: 6.339 ± 2.237
0.464AlaCys: 0.464 ± 0.221
3.556AlaAsp: 3.556 ± 0.434
5.953AlaGlu: 5.953 ± 0.677
3.247AlaPhe: 3.247 ± 0.999
6.185AlaGly: 6.185 ± 1.18
0.541AlaHis: 0.541 ± 0.256
5.644AlaIle: 5.644 ± 1.192
8.04AlaLys: 8.04 ± 1.569
6.881AlaLeu: 6.881 ± 1.178
2.551AlaMet: 2.551 ± 0.437
4.871AlaAsn: 4.871 ± 0.654
1.237AlaPro: 1.237 ± 0.366
2.629AlaGln: 2.629 ± 0.411
1.933AlaArg: 1.933 ± 0.425
4.097AlaSer: 4.097 ± 0.862
4.948AlaThr: 4.948 ± 0.697
4.484AlaVal: 4.484 ± 1.377
0.773AlaTrp: 0.773 ± 0.32
2.551AlaTyr: 2.551 ± 0.435
0.0AlaXaa: 0.0 ± 0.0
Cys
0.232CysAla: 0.232 ± 0.157
0.232CysCys: 0.232 ± 0.163
0.618CysAsp: 0.618 ± 0.258
0.541CysGlu: 0.541 ± 0.248
0.232CysPhe: 0.232 ± 0.138
1.082CysGly: 1.082 ± 0.431
0.155CysHis: 0.155 ± 0.1
0.077CysIle: 0.077 ± 0.086
0.309CysLys: 0.309 ± 0.143
0.773CysLeu: 0.773 ± 0.279
0.232CysMet: 0.232 ± 0.128
0.232CysAsn: 0.232 ± 0.14
0.387CysPro: 0.387 ± 0.253
0.077CysGln: 0.077 ± 0.075
0.464CysArg: 0.464 ± 0.157
0.309CysSer: 0.309 ± 0.146
0.077CysThr: 0.077 ± 0.085
0.232CysVal: 0.232 ± 0.135
0.077CysTrp: 0.077 ± 0.073
0.541CysTyr: 0.541 ± 0.195
0.0CysXaa: 0.0 ± 0.0
Asp
3.479AspAla: 3.479 ± 0.862
0.387AspCys: 0.387 ± 0.161
4.407AspAsp: 4.407 ± 0.841
5.18AspGlu: 5.18 ± 1.027
3.015AspPhe: 3.015 ± 0.477
3.324AspGly: 3.324 ± 0.451
0.232AspHis: 0.232 ± 0.11
4.02AspIle: 4.02 ± 0.413
5.334AspLys: 5.334 ± 0.579
5.18AspLeu: 5.18 ± 0.619
1.778AspMet: 1.778 ± 0.398
3.402AspAsn: 3.402 ± 0.486
0.928AspPro: 0.928 ± 0.192
1.237AspGln: 1.237 ± 0.265
1.701AspArg: 1.701 ± 0.423
4.329AspSer: 4.329 ± 0.816
2.706AspThr: 2.706 ± 0.411
2.86AspVal: 2.86 ± 0.396
1.082AspTrp: 1.082 ± 0.352
3.634AspTyr: 3.634 ± 0.677
0.0AspXaa: 0.0 ± 0.0
Glu
6.649GluAla: 6.649 ± 1.0
0.541GluCys: 0.541 ± 0.187
3.788GluAsp: 3.788 ± 0.771
6.803GluGlu: 6.803 ± 1.246
3.092GluPhe: 3.092 ± 0.618
2.319GluGly: 2.319 ± 0.481
1.314GluHis: 1.314 ± 0.384
5.953GluIle: 5.953 ± 0.868
8.891GluLys: 8.891 ± 0.928
8.427GluLeu: 8.427 ± 1.1
2.629GluMet: 2.629 ± 0.476
4.871GluAsn: 4.871 ± 0.634
1.469GluPro: 1.469 ± 0.429
2.938GluGln: 2.938 ± 0.653
3.247GluArg: 3.247 ± 0.621
4.097GluSer: 4.097 ± 0.486
3.479GluThr: 3.479 ± 0.536
4.484GluVal: 4.484 ± 0.801
0.85GluTrp: 0.85 ± 0.352
3.092GluTyr: 3.092 ± 0.575
0.0GluXaa: 0.0 ± 0.0
Phe
3.402PheAla: 3.402 ± 0.348
0.155PheCys: 0.155 ± 0.103
2.938PheAsp: 2.938 ± 0.604
2.397PheGlu: 2.397 ± 0.574
0.928PhePhe: 0.928 ± 0.215
2.319PheGly: 2.319 ± 0.365
0.387PheHis: 0.387 ± 0.198
2.938PheIle: 2.938 ± 0.491
2.474PheLys: 2.474 ± 0.369
3.402PheLeu: 3.402 ± 0.477
0.928PheMet: 0.928 ± 0.293
2.165PheAsn: 2.165 ± 0.355
0.618PhePro: 0.618 ± 0.238
1.314PheGln: 1.314 ± 0.295
0.928PheArg: 0.928 ± 0.286
3.556PheSer: 3.556 ± 0.478
2.783PheThr: 2.783 ± 0.52
3.015PheVal: 3.015 ± 0.482
0.696PheTrp: 0.696 ± 0.28
1.237PheTyr: 1.237 ± 0.314
0.0PheXaa: 0.0 ± 0.0
Gly
3.943GlyAla: 3.943 ± 1.254
0.773GlyCys: 0.773 ± 0.274
3.17GlyAsp: 3.17 ± 0.4
3.015GlyGlu: 3.015 ± 0.441
2.86GlyPhe: 2.86 ± 0.524
3.479GlyGly: 3.479 ± 0.48
0.773GlyHis: 0.773 ± 0.249
3.788GlyIle: 3.788 ± 0.479
4.948GlyLys: 4.948 ± 0.555
5.566GlyLeu: 5.566 ± 0.806
1.624GlyMet: 1.624 ± 0.328
4.097GlyAsn: 4.097 ± 0.651
0.232GlyPro: 0.232 ± 0.117
2.165GlyGln: 2.165 ± 0.411
1.933GlyArg: 1.933 ± 0.402
4.716GlySer: 4.716 ± 0.898
4.175GlyThr: 4.175 ± 0.723
3.865GlyVal: 3.865 ± 0.838
0.618GlyTrp: 0.618 ± 0.27
2.474GlyTyr: 2.474 ± 0.539
0.0GlyXaa: 0.0 ± 0.0
His
0.773HisAla: 0.773 ± 0.27
0.077HisCys: 0.077 ± 0.079
0.618HisAsp: 0.618 ± 0.204
0.85HisGlu: 0.85 ± 0.363
0.387HisPhe: 0.387 ± 0.191
0.387HisGly: 0.387 ± 0.16
0.464HisHis: 0.464 ± 0.201
0.773HisIle: 0.773 ± 0.29
0.618HisLys: 0.618 ± 0.264
1.16HisLeu: 1.16 ± 0.289
0.077HisMet: 0.077 ± 0.097
1.005HisAsn: 1.005 ± 0.353
0.618HisPro: 0.618 ± 0.218
0.387HisGln: 0.387 ± 0.22
0.541HisArg: 0.541 ± 0.216
0.85HisSer: 0.85 ± 0.231
0.85HisThr: 0.85 ± 0.28
0.928HisVal: 0.928 ± 0.303
0.387HisTrp: 0.387 ± 0.174
0.464HisTyr: 0.464 ± 0.196
0.0HisXaa: 0.0 ± 0.0
Ile
4.948IleAla: 4.948 ± 0.814
0.387IleCys: 0.387 ± 0.176
6.03IleAsp: 6.03 ± 0.745
7.808IleGlu: 7.808 ± 0.998
2.474IlePhe: 2.474 ± 0.622
2.706IleGly: 2.706 ± 0.442
1.237IleHis: 1.237 ± 0.365
4.407IleIle: 4.407 ± 0.592
7.654IleLys: 7.654 ± 0.973
5.102IleLeu: 5.102 ± 0.564
1.855IleMet: 1.855 ± 0.42
5.18IleAsn: 5.18 ± 0.578
2.165IlePro: 2.165 ± 0.347
2.397IleGln: 2.397 ± 0.493
2.087IleArg: 2.087 ± 0.329
4.484IleSer: 4.484 ± 0.602
3.788IleThr: 3.788 ± 0.502
3.247IleVal: 3.247 ± 0.474
0.541IleTrp: 0.541 ± 0.207
2.397IleTyr: 2.397 ± 0.533
0.0IleXaa: 0.0 ± 0.0
Lys
7.499LysAla: 7.499 ± 1.109
0.464LysCys: 0.464 ± 0.23
4.871LysAsp: 4.871 ± 0.564
8.04LysGlu: 8.04 ± 1.16
2.706LysPhe: 2.706 ± 0.5
5.025LysGly: 5.025 ± 0.686
0.85LysHis: 0.85 ± 0.289
4.407LysIle: 4.407 ± 0.745
8.427LysLys: 8.427 ± 0.882
7.19LysLeu: 7.19 ± 0.721
3.247LysMet: 3.247 ± 0.624
5.489LysAsn: 5.489 ± 0.761
2.242LysPro: 2.242 ± 0.422
4.793LysGln: 4.793 ± 0.699
3.788LysArg: 3.788 ± 0.609
5.489LysSer: 5.489 ± 1.602
5.953LysThr: 5.953 ± 0.712
5.721LysVal: 5.721 ± 0.628
1.546LysTrp: 1.546 ± 0.276
3.943LysTyr: 3.943 ± 0.559
0.0LysXaa: 0.0 ± 0.0
Leu
8.504LeuAla: 8.504 ± 1.049
0.541LeuCys: 0.541 ± 0.206
5.257LeuAsp: 5.257 ± 0.592
6.262LeuGlu: 6.262 ± 1.018
3.17LeuPhe: 3.17 ± 0.636
4.097LeuGly: 4.097 ± 0.625
0.85LeuHis: 0.85 ± 0.229
5.953LeuIle: 5.953 ± 0.755
9.045LeuLys: 9.045 ± 0.807
6.494LeuLeu: 6.494 ± 0.946
1.314LeuMet: 1.314 ± 0.373
5.412LeuAsn: 5.412 ± 0.669
2.551LeuPro: 2.551 ± 0.31
2.397LeuGln: 2.397 ± 0.423
2.629LeuArg: 2.629 ± 0.548
5.489LeuSer: 5.489 ± 0.662
4.793LeuThr: 4.793 ± 0.539
5.102LeuVal: 5.102 ± 0.578
0.387LeuTrp: 0.387 ± 0.183
2.86LeuTyr: 2.86 ± 0.52
0.0LeuXaa: 0.0 ± 0.0
Met
1.469MetAla: 1.469 ± 0.32
0.077MetCys: 0.077 ± 0.08
0.773MetAsp: 0.773 ± 0.239
1.16MetGlu: 1.16 ± 0.239
1.237MetPhe: 1.237 ± 0.317
1.624MetGly: 1.624 ± 0.313
0.232MetHis: 0.232 ± 0.145
1.778MetIle: 1.778 ± 0.389
2.087MetLys: 2.087 ± 0.398
1.624MetLeu: 1.624 ± 0.275
0.696MetMet: 0.696 ± 0.283
2.319MetAsn: 2.319 ± 0.457
0.773MetPro: 0.773 ± 0.287
1.16MetGln: 1.16 ± 0.281
1.005MetArg: 1.005 ± 0.26
2.474MetSer: 2.474 ± 0.361
2.397MetThr: 2.397 ± 0.386
1.392MetVal: 1.392 ± 0.252
0.309MetTrp: 0.309 ± 0.162
1.082MetTyr: 1.082 ± 0.258
0.0MetXaa: 0.0 ± 0.0
Asn
4.02AsnAla: 4.02 ± 0.888
0.387AsnCys: 0.387 ± 0.189
2.938AsnAsp: 2.938 ± 0.592
5.334AsnGlu: 5.334 ± 0.974
1.701AsnPhe: 1.701 ± 0.354
5.025AsnGly: 5.025 ± 0.672
0.773AsnHis: 0.773 ± 0.22
4.252AsnIle: 4.252 ± 0.625
5.257AsnLys: 5.257 ± 0.714
4.639AsnLeu: 4.639 ± 0.499
1.778AsnMet: 1.778 ± 0.297
4.871AsnAsn: 4.871 ± 0.894
1.855AsnPro: 1.855 ± 0.445
3.17AsnGln: 3.17 ± 0.478
2.783AsnArg: 2.783 ± 0.481
3.865AsnSer: 3.865 ± 0.778
3.556AsnThr: 3.556 ± 0.608
4.02AsnVal: 4.02 ± 0.488
0.541AsnTrp: 0.541 ± 0.267
2.629AsnTyr: 2.629 ± 0.567
0.0AsnXaa: 0.0 ± 0.0
Pro
2.087ProAla: 2.087 ± 0.436
0.232ProCys: 0.232 ± 0.118
1.624ProAsp: 1.624 ± 0.355
1.778ProGlu: 1.778 ± 0.374
0.618ProPhe: 0.618 ± 0.218
0.773ProGly: 0.773 ± 0.241
0.541ProHis: 0.541 ± 0.237
1.701ProIle: 1.701 ± 0.385
1.314ProLys: 1.314 ± 0.305
1.933ProLeu: 1.933 ± 0.416
0.464ProMet: 0.464 ± 0.195
1.392ProAsn: 1.392 ± 0.357
0.696ProPro: 0.696 ± 0.217
0.773ProGln: 0.773 ± 0.248
1.16ProArg: 1.16 ± 0.334
1.701ProSer: 1.701 ± 0.34
1.392ProThr: 1.392 ± 0.28
1.933ProVal: 1.933 ± 0.355
0.077ProTrp: 0.077 ± 0.081
0.541ProTyr: 0.541 ± 0.213
0.0ProXaa: 0.0 ± 0.0
Gln
3.479GlnAla: 3.479 ± 0.861
0.387GlnCys: 0.387 ± 0.183
1.546GlnAsp: 1.546 ± 0.45
3.015GlnGlu: 3.015 ± 0.628
1.624GlnPhe: 1.624 ± 0.317
1.778GlnGly: 1.778 ± 0.416
0.387GlnHis: 0.387 ± 0.22
3.324GlnIle: 3.324 ± 0.477
3.092GlnLys: 3.092 ± 0.605
3.402GlnLeu: 3.402 ± 0.546
0.541GlnMet: 0.541 ± 0.189
1.855GlnAsn: 1.855 ± 0.398
0.464GlnPro: 0.464 ± 0.198
2.087GlnGln: 2.087 ± 0.504
1.855GlnArg: 1.855 ± 0.38
2.087GlnSer: 2.087 ± 0.567
2.551GlnThr: 2.551 ± 0.331
2.474GlnVal: 2.474 ± 0.398
0.309GlnTrp: 0.309 ± 0.15
1.237GlnTyr: 1.237 ± 0.261
0.0GlnXaa: 0.0 ± 0.0
Arg
2.087ArgAla: 2.087 ± 0.459
0.155ArgCys: 0.155 ± 0.109
2.01ArgAsp: 2.01 ± 0.477
2.938ArgGlu: 2.938 ± 0.599
1.314ArgPhe: 1.314 ± 0.331
1.855ArgGly: 1.855 ± 0.422
0.464ArgHis: 0.464 ± 0.168
2.706ArgIle: 2.706 ± 0.502
3.943ArgLys: 3.943 ± 0.751
2.938ArgLeu: 2.938 ± 0.388
0.773ArgMet: 0.773 ± 0.271
1.469ArgAsn: 1.469 ± 0.422
0.85ArgPro: 0.85 ± 0.237
1.314ArgGln: 1.314 ± 0.434
1.314ArgArg: 1.314 ± 0.342
2.629ArgSer: 2.629 ± 0.41
1.933ArgThr: 1.933 ± 0.374
2.087ArgVal: 2.087 ± 0.466
0.618ArgTrp: 0.618 ± 0.25
1.469ArgTyr: 1.469 ± 0.408
0.0ArgXaa: 0.0 ± 0.0
Ser
5.644SerAla: 5.644 ± 1.492
0.155SerCys: 0.155 ± 0.128
4.175SerAsp: 4.175 ± 0.553
5.025SerGlu: 5.025 ± 0.672
2.938SerPhe: 2.938 ± 0.485
5.334SerGly: 5.334 ± 1.186
0.618SerHis: 0.618 ± 0.176
5.644SerIle: 5.644 ± 0.849
5.412SerLys: 5.412 ± 0.536
5.257SerLeu: 5.257 ± 0.729
1.237SerMet: 1.237 ± 0.255
4.639SerAsn: 4.639 ± 0.48
1.005SerPro: 1.005 ± 0.299
2.165SerGln: 2.165 ± 0.382
2.087SerArg: 2.087 ± 0.436
3.479SerSer: 3.479 ± 0.67
4.329SerThr: 4.329 ± 0.749
4.484SerVal: 4.484 ± 0.691
0.155SerTrp: 0.155 ± 0.098
2.474SerTyr: 2.474 ± 0.463
0.0SerXaa: 0.0 ± 0.0
Thr
4.716ThrAla: 4.716 ± 1.33
0.541ThrCys: 0.541 ± 0.206
2.706ThrAsp: 2.706 ± 0.542
4.793ThrGlu: 4.793 ± 0.795
3.092ThrPhe: 3.092 ± 0.59
3.788ThrGly: 3.788 ± 0.684
0.928ThrHis: 0.928 ± 0.282
5.18ThrIle: 5.18 ± 0.655
5.18ThrLys: 5.18 ± 0.691
4.639ThrLeu: 4.639 ± 0.596
1.469ThrMet: 1.469 ± 0.327
3.788ThrAsn: 3.788 ± 0.571
2.165ThrPro: 2.165 ± 0.45
1.392ThrGln: 1.392 ± 0.251
1.546ThrArg: 1.546 ± 0.423
4.329ThrSer: 4.329 ± 0.534
4.175ThrThr: 4.175 ± 0.746
4.097ThrVal: 4.097 ± 0.58
0.387ThrTrp: 0.387 ± 0.145
2.087ThrTyr: 2.087 ± 0.526
0.0ThrXaa: 0.0 ± 0.0
Val
5.025ValAla: 5.025 ± 0.743
0.387ValCys: 0.387 ± 0.188
4.407ValAsp: 4.407 ± 0.609
4.407ValGlu: 4.407 ± 0.53
2.087ValPhe: 2.087 ± 0.354
3.711ValGly: 3.711 ± 0.61
1.005ValHis: 1.005 ± 0.317
4.871ValIle: 4.871 ± 0.617
5.721ValLys: 5.721 ± 0.816
4.252ValLeu: 4.252 ± 0.485
1.005ValMet: 1.005 ± 0.249
2.783ValAsn: 2.783 ± 0.416
1.469ValPro: 1.469 ± 0.334
2.629ValGln: 2.629 ± 0.399
1.778ValArg: 1.778 ± 0.509
4.716ValSer: 4.716 ± 0.694
4.561ValThr: 4.561 ± 0.515
5.412ValVal: 5.412 ± 0.702
0.541ValTrp: 0.541 ± 0.232
2.087ValTyr: 2.087 ± 0.455
0.0ValXaa: 0.0 ± 0.0
Trp
0.696TrpAla: 0.696 ± 0.257
0.0TrpCys: 0.0 ± 0.0
0.541TrpAsp: 0.541 ± 0.194
0.928TrpGlu: 0.928 ± 0.334
0.387TrpPhe: 0.387 ± 0.179
0.618TrpGly: 0.618 ± 0.243
0.077TrpHis: 0.077 ± 0.074
1.082TrpIle: 1.082 ± 0.39
0.773TrpLys: 0.773 ± 0.276
1.314TrpLeu: 1.314 ± 0.385
0.309TrpMet: 0.309 ± 0.159
1.082TrpAsn: 1.082 ± 0.381
0.077TrpPro: 0.077 ± 0.081
0.541TrpGln: 0.541 ± 0.172
0.309TrpArg: 0.309 ± 0.211
0.309TrpSer: 0.309 ± 0.202
0.387TrpThr: 0.387 ± 0.181
0.696TrpVal: 0.696 ± 0.223
0.155TrpTrp: 0.155 ± 0.11
0.232TrpTyr: 0.232 ± 0.126
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.933TyrAla: 1.933 ± 0.365
0.541TyrCys: 0.541 ± 0.244
2.242TyrAsp: 2.242 ± 0.524
2.706TyrGlu: 2.706 ± 0.68
1.469TyrPhe: 1.469 ± 0.306
2.783TyrGly: 2.783 ± 0.545
0.387TyrHis: 0.387 ± 0.157
2.397TyrIle: 2.397 ± 0.555
3.247TyrLys: 3.247 ± 0.657
2.938TyrLeu: 2.938 ± 0.711
1.082TyrMet: 1.082 ± 0.274
2.474TyrAsn: 2.474 ± 0.582
0.928TyrPro: 0.928 ± 0.286
1.933TyrGln: 1.933 ± 0.446
1.778TyrArg: 1.778 ± 0.409
3.247TyrSer: 3.247 ± 0.537
2.165TyrThr: 2.165 ± 0.455
2.319TyrVal: 2.319 ± 0.463
0.464TyrTrp: 0.464 ± 0.211
2.551TyrTyr: 2.551 ± 0.603
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 73 proteins (12936 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski