Amino acid dipepetide frequency for Gordonia soli NBRC 108243

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
19.024AlaAla: 19.024 ± 0.17
0.76AlaCys: 0.76 ± 0.024
10.009AlaAsp: 10.009 ± 0.101
7.362AlaGlu: 7.362 ± 0.081
3.335AlaPhe: 3.335 ± 0.052
11.814AlaGly: 11.814 ± 0.099
2.589AlaHis: 2.589 ± 0.044
5.699AlaIle: 5.699 ± 0.071
2.39AlaLys: 2.39 ± 0.054
12.009AlaLeu: 12.009 ± 0.108
2.592AlaMet: 2.592 ± 0.04
2.243AlaAsn: 2.243 ± 0.042
6.247AlaPro: 6.247 ± 0.081
3.605AlaGln: 3.605 ± 0.05
8.927AlaArg: 8.927 ± 0.077
6.384AlaSer: 6.384 ± 0.06
7.896AlaThr: 7.896 ± 0.077
11.765AlaVal: 11.765 ± 0.115
1.518AlaTrp: 1.518 ± 0.03
2.161AlaTyr: 2.161 ± 0.039
0.0AlaXaa: 0.0 ± 0.0
Cys
0.882CysAla: 0.882 ± 0.022
0.073CysCys: 0.073 ± 0.007
0.406CysAsp: 0.406 ± 0.017
0.303CysGlu: 0.303 ± 0.012
0.187CysPhe: 0.187 ± 0.01
0.764CysGly: 0.764 ± 0.025
0.144CysHis: 0.144 ± 0.009
0.244CysIle: 0.244 ± 0.012
0.08CysLys: 0.08 ± 0.007
0.519CysLeu: 0.519 ± 0.021
0.101CysMet: 0.101 ± 0.008
0.134CysAsn: 0.134 ± 0.009
0.372CysPro: 0.372 ± 0.018
0.138CysGln: 0.138 ± 0.008
0.504CysArg: 0.504 ± 0.017
0.41CysSer: 0.41 ± 0.015
0.401CysThr: 0.401 ± 0.017
0.566CysVal: 0.566 ± 0.019
0.095CysTrp: 0.095 ± 0.008
0.133CysTyr: 0.133 ± 0.01
0.0CysXaa: 0.0 ± 0.0
Asp
8.624AspAla: 8.624 ± 0.086
0.354AspCys: 0.354 ± 0.018
5.435AspAsp: 5.435 ± 0.071
4.511AspGlu: 4.511 ± 0.061
1.761AspPhe: 1.761 ± 0.036
6.489AspGly: 6.489 ± 0.065
1.902AspHis: 1.902 ± 0.037
2.7AspIle: 2.7 ± 0.043
1.155AspLys: 1.155 ± 0.033
6.989AspLeu: 6.989 ± 0.08
0.888AspMet: 0.888 ± 0.023
1.178AspAsn: 1.178 ± 0.032
4.793AspPro: 4.793 ± 0.066
1.892AspGln: 1.892 ± 0.032
5.73AspArg: 5.73 ± 0.069
3.364AspSer: 3.364 ± 0.052
3.522AspThr: 3.522 ± 0.046
5.807AspVal: 5.807 ± 0.08
0.957AspTrp: 0.957 ± 0.029
1.275AspTyr: 1.275 ± 0.034
0.0AspXaa: 0.0 ± 0.0
Glu
5.495GluAla: 5.495 ± 0.065
0.294GluCys: 0.294 ± 0.014
2.326GluAsp: 2.326 ± 0.048
2.301GluGlu: 2.301 ± 0.054
1.857GluPhe: 1.857 ± 0.036
3.178GluGly: 3.178 ± 0.051
1.453GluHis: 1.453 ± 0.031
3.018GluIle: 3.018 ± 0.044
1.296GluLys: 1.296 ± 0.034
6.122GluLeu: 6.122 ± 0.078
0.953GluMet: 0.953 ± 0.026
1.179GluAsn: 1.179 ± 0.034
2.883GluPro: 2.883 ± 0.042
2.038GluGln: 2.038 ± 0.042
4.489GluArg: 4.489 ± 0.061
3.278GluSer: 3.278 ± 0.044
2.748GluThr: 2.748 ± 0.041
4.681GluVal: 4.681 ± 0.061
0.809GluTrp: 0.809 ± 0.024
1.107GluTyr: 1.107 ± 0.028
0.0GluXaa: 0.0 ± 0.0
Phe
4.023PheAla: 4.023 ± 0.06
0.257PheCys: 0.257 ± 0.012
2.51PheAsp: 2.51 ± 0.047
1.415PheGlu: 1.415 ± 0.033
0.95PhePhe: 0.95 ± 0.032
3.513PheGly: 3.513 ± 0.053
0.574PheHis: 0.574 ± 0.02
1.032PheIle: 1.032 ± 0.027
0.4PheLys: 0.4 ± 0.017
2.459PheLeu: 2.459 ± 0.041
0.412PheMet: 0.412 ± 0.015
0.602PheAsn: 0.602 ± 0.02
1.344PhePro: 1.344 ± 0.03
0.62PheGln: 0.62 ± 0.019
1.762PheArg: 1.762 ± 0.037
1.604PheSer: 1.604 ± 0.036
2.04PheThr: 2.04 ± 0.04
2.732PheVal: 2.732 ± 0.044
0.41PheTrp: 0.41 ± 0.016
0.644PheTyr: 0.644 ± 0.021
0.0PheXaa: 0.0 ± 0.0
Gly
10.456GlyAla: 10.456 ± 0.085
0.685GlyCys: 0.685 ± 0.025
5.592GlyAsp: 5.592 ± 0.062
4.495GlyGlu: 4.495 ± 0.058
3.036GlyPhe: 3.036 ± 0.049
8.191GlyGly: 8.191 ± 0.115
2.051GlyHis: 2.051 ± 0.039
4.297GlyIle: 4.297 ± 0.058
2.128GlyLys: 2.128 ± 0.04
8.503GlyLeu: 8.503 ± 0.076
1.857GlyMet: 1.857 ± 0.036
1.775GlyAsn: 1.775 ± 0.038
4.615GlyPro: 4.615 ± 0.061
2.606GlyGln: 2.606 ± 0.042
7.01GlyArg: 7.01 ± 0.071
5.851GlySer: 5.851 ± 0.067
5.665GlyThr: 5.665 ± 0.064
8.186GlyVal: 8.186 ± 0.081
1.556GlyTrp: 1.556 ± 0.033
2.243GlyTyr: 2.243 ± 0.04
0.0GlyXaa: 0.0 ± 0.0
His
2.309HisAla: 2.309 ± 0.041
0.172HisCys: 0.172 ± 0.009
1.389HisAsp: 1.389 ± 0.026
1.051HisGlu: 1.051 ± 0.027
0.615HisPhe: 0.615 ± 0.022
2.052HisGly: 2.052 ± 0.038
0.708HisHis: 0.708 ± 0.019
0.824HisIle: 0.824 ± 0.026
0.311HisLys: 0.311 ± 0.015
2.252HisLeu: 2.252 ± 0.039
0.303HisMet: 0.303 ± 0.016
0.39HisAsn: 0.39 ± 0.016
1.685HisPro: 1.685 ± 0.034
0.596HisGln: 0.596 ± 0.02
2.146HisArg: 2.146 ± 0.042
1.113HisSer: 1.113 ± 0.031
1.139HisThr: 1.139 ± 0.029
1.667HisVal: 1.667 ± 0.037
0.33HisTrp: 0.33 ± 0.013
0.466HisTyr: 0.466 ± 0.017
0.0HisXaa: 0.0 ± 0.0
Ile
7.012IleAla: 7.012 ± 0.068
0.341IleCys: 0.341 ± 0.016
3.87IleAsp: 3.87 ± 0.049
2.58IleGlu: 2.58 ± 0.048
1.003IlePhe: 1.003 ± 0.029
4.908IleGly: 4.908 ± 0.06
0.773IleHis: 0.773 ± 0.023
1.642IleIle: 1.642 ± 0.033
0.734IleLys: 0.734 ± 0.023
3.432IleLeu: 3.432 ± 0.05
0.563IleMet: 0.563 ± 0.018
0.965IleAsn: 0.965 ± 0.023
2.53IlePro: 2.53 ± 0.043
0.842IleGln: 0.842 ± 0.026
3.039IleArg: 3.039 ± 0.044
2.477IleSer: 2.477 ± 0.037
2.946IleThr: 2.946 ± 0.046
4.297IleVal: 4.297 ± 0.052
0.502IleTrp: 0.502 ± 0.017
0.746IleTyr: 0.746 ± 0.021
0.0IleXaa: 0.0 ± 0.0
Lys
2.24LysAla: 2.24 ± 0.05
0.092LysCys: 0.092 ± 0.008
0.992LysAsp: 0.992 ± 0.03
0.826LysGlu: 0.826 ± 0.026
0.53LysPhe: 0.53 ± 0.02
1.449LysGly: 1.449 ± 0.04
0.386LysHis: 0.386 ± 0.017
0.929LysIle: 0.929 ± 0.029
0.696LysLys: 0.696 ± 0.033
1.782LysLeu: 1.782 ± 0.042
0.362LysMet: 0.362 ± 0.015
0.507LysAsn: 0.507 ± 0.02
1.094LysPro: 1.094 ± 0.029
0.602LysGln: 0.602 ± 0.022
1.389LysArg: 1.389 ± 0.035
1.181LysSer: 1.181 ± 0.03
1.227LysThr: 1.227 ± 0.033
1.756LysVal: 1.756 ± 0.038
0.243LysTrp: 0.243 ± 0.014
0.454LysTyr: 0.454 ± 0.02
0.0LysXaa: 0.0 ± 0.0
Leu
12.952LeuAla: 12.952 ± 0.103
0.648LeuCys: 0.648 ± 0.02
6.967LeuAsp: 6.967 ± 0.075
4.145LeuGlu: 4.145 ± 0.066
2.676LeuPhe: 2.676 ± 0.048
8.617LeuGly: 8.617 ± 0.073
1.832LeuHis: 1.832 ± 0.032
4.234LeuIle: 4.234 ± 0.053
1.507LeuLys: 1.507 ± 0.037
8.787LeuLeu: 8.787 ± 0.093
1.511LeuMet: 1.511 ± 0.031
1.707LeuAsn: 1.707 ± 0.036
5.298LeuPro: 5.298 ± 0.066
2.128LeuGln: 2.128 ± 0.04
7.403LeuArg: 7.403 ± 0.069
5.605LeuSer: 5.605 ± 0.061
6.392LeuThr: 6.392 ± 0.061
8.729LeuVal: 8.729 ± 0.074
1.182LeuTrp: 1.182 ± 0.034
1.569LeuTyr: 1.569 ± 0.032
0.0LeuXaa: 0.0 ± 0.0
Met
2.186MetAla: 2.186 ± 0.037
0.13MetCys: 0.13 ± 0.01
0.765MetAsp: 0.765 ± 0.022
0.611MetGlu: 0.611 ± 0.021
0.569MetPhe: 0.569 ± 0.022
1.298MetGly: 1.298 ± 0.03
0.345MetHis: 0.345 ± 0.015
0.915MetIle: 0.915 ± 0.023
0.353MetLys: 0.353 ± 0.018
1.715MetLeu: 1.715 ± 0.034
0.36MetMet: 0.36 ± 0.015
0.437MetAsn: 0.437 ± 0.016
1.017MetPro: 1.017 ± 0.023
0.447MetGln: 0.447 ± 0.017
1.35MetArg: 1.35 ± 0.031
1.713MetSer: 1.713 ± 0.034
1.812MetThr: 1.812 ± 0.036
1.571MetVal: 1.571 ± 0.032
0.223MetTrp: 0.223 ± 0.012
0.294MetTyr: 0.294 ± 0.014
0.0MetXaa: 0.0 ± 0.0
Asn
2.287AsnAla: 2.287 ± 0.038
0.133AsnCys: 0.133 ± 0.009
1.052AsnAsp: 1.052 ± 0.028
0.866AsnGlu: 0.866 ± 0.025
0.579AsnPhe: 0.579 ± 0.021
2.061AsnGly: 2.061 ± 0.05
0.429AsnHis: 0.429 ± 0.017
0.863AsnIle: 0.863 ± 0.027
0.409AsnLys: 0.409 ± 0.02
1.826AsnLeu: 1.826 ± 0.04
0.325AsnMet: 0.325 ± 0.015
0.46AsnAsn: 0.46 ± 0.018
1.594AsnPro: 1.594 ± 0.034
0.574AsnGln: 0.574 ± 0.023
1.487AsnArg: 1.487 ± 0.034
1.182AsnSer: 1.182 ± 0.028
1.204AsnThr: 1.204 ± 0.029
1.56AsnVal: 1.56 ± 0.035
0.31AsnTrp: 0.31 ± 0.016
0.457AsnTyr: 0.457 ± 0.016
0.0AsnXaa: 0.0 ± 0.0
Pro
6.92ProAla: 6.92 ± 0.081
0.235ProCys: 0.235 ± 0.013
4.893ProAsp: 4.893 ± 0.063
3.485ProGlu: 3.485 ± 0.05
1.601ProPhe: 1.601 ± 0.033
5.41ProGly: 5.41 ± 0.073
1.152ProHis: 1.152 ± 0.028
2.393ProIle: 2.393 ± 0.041
1.108ProLys: 1.108 ± 0.026
4.486ProLeu: 4.486 ± 0.057
1.037ProMet: 1.037 ± 0.022
1.126ProAsn: 1.126 ± 0.033
2.982ProPro: 2.982 ± 0.062
1.584ProGln: 1.584 ± 0.034
3.596ProArg: 3.596 ± 0.052
3.351ProSer: 3.351 ± 0.053
4.328ProThr: 4.328 ± 0.058
4.935ProVal: 4.935 ± 0.059
0.803ProTrp: 0.803 ± 0.023
1.052ProTyr: 1.052 ± 0.029
0.0ProXaa: 0.0 ± 0.0
Gln
3.087GlnAla: 3.087 ± 0.046
0.173GlnCys: 0.173 ± 0.011
1.043GlnAsp: 1.043 ± 0.026
1.039GlnGlu: 1.039 ± 0.024
0.881GlnPhe: 0.881 ± 0.026
1.861GlnGly: 1.861 ± 0.041
0.576GlnHis: 0.576 ± 0.017
1.578GlnIle: 1.578 ± 0.034
0.586GlnLys: 0.586 ± 0.022
2.861GlnLeu: 2.861 ± 0.053
0.584GlnMet: 0.584 ± 0.022
0.601GlnAsn: 0.601 ± 0.02
1.591GlnPro: 1.591 ± 0.031
1.201GlnGln: 1.201 ± 0.03
2.404GlnArg: 2.404 ± 0.043
1.539GlnSer: 1.539 ± 0.036
1.525GlnThr: 1.525 ± 0.03
2.496GlnVal: 2.496 ± 0.043
0.477GlnTrp: 0.477 ± 0.017
0.601GlnTyr: 0.601 ± 0.021
0.0GlnXaa: 0.0 ± 0.0
Arg
8.668ArgAla: 8.668 ± 0.085
0.497ArgCys: 0.497 ± 0.019
4.753ArgAsp: 4.753 ± 0.057
3.957ArgGlu: 3.957 ± 0.06
2.4ArgPhe: 2.4 ± 0.039
5.561ArgGly: 5.561 ± 0.061
1.855ArgHis: 1.855 ± 0.041
3.728ArgIle: 3.728 ± 0.055
1.423ArgLys: 1.423 ± 0.033
7.355ArgLeu: 7.355 ± 0.079
1.812ArgMet: 1.812 ± 0.031
1.532ArgAsn: 1.532 ± 0.03
4.386ArgPro: 4.386 ± 0.061
2.052ArgGln: 2.052 ± 0.038
7.268ArgArg: 7.268 ± 0.092
4.96ArgSer: 4.96 ± 0.059
4.8ArgThr: 4.8 ± 0.061
5.878ArgVal: 5.878 ± 0.073
1.431ArgTrp: 1.431 ± 0.032
1.696ArgTyr: 1.696 ± 0.037
0.0ArgXaa: 0.0 ± 0.0
Ser
7.911SerAla: 7.911 ± 0.078
0.337SerCys: 0.337 ± 0.016
3.818SerAsp: 3.818 ± 0.054
2.826SerGlu: 2.826 ± 0.047
1.642SerPhe: 1.642 ± 0.032
6.343SerGly: 6.343 ± 0.071
1.008SerHis: 1.008 ± 0.027
2.553SerIle: 2.553 ± 0.042
1.073SerLys: 1.073 ± 0.033
4.834SerLeu: 4.834 ± 0.052
1.344SerMet: 1.344 ± 0.025
1.069SerAsn: 1.069 ± 0.029
3.275SerPro: 3.275 ± 0.047
1.383SerGln: 1.383 ± 0.03
4.109SerArg: 4.109 ± 0.055
3.611SerSer: 3.611 ± 0.058
4.166SerThr: 4.166 ± 0.055
5.361SerVal: 5.361 ± 0.065
0.93SerTrp: 0.93 ± 0.03
1.149SerTyr: 1.149 ± 0.027
0.0SerXaa: 0.0 ± 0.0
Thr
8.48ThrAla: 8.48 ± 0.089
0.354ThrCys: 0.354 ± 0.014
4.641ThrAsp: 4.641 ± 0.054
3.405ThrGlu: 3.405 ± 0.048
1.841ThrPhe: 1.841 ± 0.04
6.06ThrGly: 6.06 ± 0.066
1.208ThrHis: 1.208 ± 0.03
2.914ThrIle: 2.914 ± 0.04
1.147ThrLys: 1.147 ± 0.031
5.536ThrLeu: 5.536 ± 0.054
1.125ThrMet: 1.125 ± 0.029
1.163ThrAsn: 1.163 ± 0.028
4.2ThrPro: 4.2 ± 0.054
1.409ThrGln: 1.409 ± 0.03
4.13ThrArg: 4.13 ± 0.056
3.864ThrSer: 3.864 ± 0.049
4.671ThrThr: 4.671 ± 0.066
6.354ThrVal: 6.354 ± 0.071
0.883ThrTrp: 0.883 ± 0.026
1.266ThrTyr: 1.266 ± 0.031
0.0ThrXaa: 0.0 ± 0.0
Val
12.068ValAla: 12.068 ± 0.122
0.63ValCys: 0.63 ± 0.02
6.823ValAsp: 6.823 ± 0.078
4.751ValGlu: 4.751 ± 0.062
2.617ValPhe: 2.617 ± 0.042
8.328ValGly: 8.328 ± 0.073
1.802ValHis: 1.802 ± 0.035
4.293ValIle: 4.293 ± 0.061
1.34ValLys: 1.34 ± 0.035
8.707ValLeu: 8.707 ± 0.094
1.405ValMet: 1.405 ± 0.034
1.79ValAsn: 1.79 ± 0.038
4.76ValPro: 4.76 ± 0.058
1.843ValGln: 1.843 ± 0.031
6.243ValArg: 6.243 ± 0.062
5.069ValSer: 5.069 ± 0.056
6.053ValThr: 6.053 ± 0.065
9.513ValVal: 9.513 ± 0.105
1.029ValTrp: 1.029 ± 0.026
1.52ValTyr: 1.52 ± 0.032
0.0ValXaa: 0.0 ± 0.0
Trp
1.484TrpAla: 1.484 ± 0.031
0.126TrpCys: 0.126 ± 0.009
0.761TrpAsp: 0.761 ± 0.022
0.611TrpGlu: 0.611 ± 0.02
0.558TrpPhe: 0.558 ± 0.019
0.986TrpGly: 0.986 ± 0.029
0.339TrpHis: 0.339 ± 0.016
0.704TrpIle: 0.704 ± 0.02
0.292TrpLys: 0.292 ± 0.015
1.585TrpLeu: 1.585 ± 0.038
0.325TrpMet: 0.325 ± 0.013
0.385TrpAsn: 0.385 ± 0.017
0.713TrpPro: 0.713 ± 0.023
0.543TrpGln: 0.543 ± 0.021
1.248TrpArg: 1.248 ± 0.034
1.014TrpSer: 1.014 ± 0.026
0.965TrpThr: 0.965 ± 0.025
1.082TrpVal: 1.082 ± 0.028
0.384TrpTrp: 0.384 ± 0.017
0.31TrpTyr: 0.31 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.222TyrAla: 2.222 ± 0.042
0.164TyrCys: 0.164 ± 0.011
1.28TyrAsp: 1.28 ± 0.032
0.966TyrGlu: 0.966 ± 0.028
0.668TyrPhe: 0.668 ± 0.02
1.914TyrGly: 1.914 ± 0.039
0.395TyrHis: 0.395 ± 0.016
0.644TyrIle: 0.644 ± 0.022
0.312TyrLys: 0.312 ± 0.014
2.128TyrLeu: 2.128 ± 0.037
0.252TyrMet: 0.252 ± 0.014
0.416TyrAsn: 0.416 ± 0.016
1.101TyrPro: 1.101 ± 0.027
0.6TyrGln: 0.6 ± 0.019
1.777TyrArg: 1.777 ± 0.039
1.169TyrSer: 1.169 ± 0.028
1.147TyrThr: 1.147 ± 0.028
1.645TyrVal: 1.645 ± 0.034
0.344TyrTrp: 0.344 ± 0.014
0.437TyrTyr: 0.437 ± 0.019
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4907 proteins (1606877 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski