Amino acid dipepetide frequency for Yellowstone Lake virophage 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.083AlaAla: 3.083 ± 1.029
0.308AlaCys: 0.308 ± 0.204
2.312AlaAsp: 2.312 ± 0.66
1.233AlaGlu: 1.233 ± 0.483
2.621AlaPhe: 2.621 ± 0.548
3.7AlaGly: 3.7 ± 1.283
0.462AlaHis: 0.462 ± 0.273
3.854AlaIle: 3.854 ± 0.576
4.008AlaLys: 4.008 ± 0.648
4.316AlaLeu: 4.316 ± 1.064
0.771AlaMet: 0.771 ± 0.328
3.391AlaAsn: 3.391 ± 0.972
2.775AlaPro: 2.775 ± 0.782
2.158AlaGln: 2.158 ± 0.505
1.542AlaArg: 1.542 ± 0.534
5.087AlaSer: 5.087 ± 1.458
7.862AlaThr: 7.862 ± 2.018
2.466AlaVal: 2.466 ± 0.522
0.925AlaTrp: 0.925 ± 0.349
2.158AlaTyr: 2.158 ± 0.469
0.0AlaXaa: 0.0 ± 0.0
Cys
0.771CysAla: 0.771 ± 0.257
0.462CysCys: 0.462 ± 0.282
0.925CysAsp: 0.925 ± 0.383
0.617CysGlu: 0.617 ± 0.302
0.925CysPhe: 0.925 ± 0.272
1.387CysGly: 1.387 ± 0.451
0.0CysHis: 0.0 ± 0.0
0.925CysIle: 0.925 ± 0.354
1.542CysLys: 1.542 ± 0.535
0.925CysLeu: 0.925 ± 0.37
0.462CysMet: 0.462 ± 0.237
0.617CysAsn: 0.617 ± 0.282
0.925CysPro: 0.925 ± 0.299
0.771CysGln: 0.771 ± 0.396
0.462CysArg: 0.462 ± 0.274
0.154CysSer: 0.154 ± 0.17
1.079CysThr: 1.079 ± 0.531
0.462CysVal: 0.462 ± 0.234
0.154CysTrp: 0.154 ± 0.116
0.617CysTyr: 0.617 ± 0.334
0.0CysXaa: 0.0 ± 0.0
Asp
2.621AspAla: 2.621 ± 0.815
0.617AspCys: 0.617 ± 0.248
3.546AspAsp: 3.546 ± 1.041
4.316AspGlu: 4.316 ± 1.112
3.391AspPhe: 3.391 ± 0.77
3.7AspGly: 3.7 ± 0.941
0.617AspHis: 0.617 ± 0.327
5.087AspIle: 5.087 ± 0.652
5.241AspLys: 5.241 ± 1.267
4.47AspLeu: 4.47 ± 0.579
0.925AspMet: 0.925 ± 0.505
3.237AspAsn: 3.237 ± 0.753
0.925AspPro: 0.925 ± 0.424
0.925AspGln: 0.925 ± 0.388
2.312AspArg: 2.312 ± 0.578
2.929AspSer: 2.929 ± 0.534
2.312AspThr: 2.312 ± 0.536
3.237AspVal: 3.237 ± 0.693
0.771AspTrp: 0.771 ± 0.348
2.312AspTyr: 2.312 ± 0.689
0.0AspXaa: 0.0 ± 0.0
Glu
1.542GluAla: 1.542 ± 0.6
0.771GluCys: 0.771 ± 0.367
2.312GluAsp: 2.312 ± 0.663
3.391GluGlu: 3.391 ± 0.889
1.85GluPhe: 1.85 ± 0.559
3.7GluGly: 3.7 ± 1.109
0.462GluHis: 0.462 ± 0.307
4.625GluIle: 4.625 ± 0.99
4.779GluLys: 4.779 ± 1.217
6.32GluLeu: 6.32 ± 1.018
1.233GluMet: 1.233 ± 0.445
4.625GluAsn: 4.625 ± 0.832
1.696GluPro: 1.696 ± 0.602
3.391GluGln: 3.391 ± 1.152
2.775GluArg: 2.775 ± 0.556
4.162GluSer: 4.162 ± 0.876
2.312GluThr: 2.312 ± 0.629
3.083GluVal: 3.083 ± 0.604
0.462GluTrp: 0.462 ± 0.236
2.621GluTyr: 2.621 ± 0.737
0.0GluXaa: 0.0 ± 0.0
Phe
2.621PheAla: 2.621 ± 0.771
0.925PheCys: 0.925 ± 0.383
3.083PheAsp: 3.083 ± 0.926
2.158PheGlu: 2.158 ± 0.449
2.466PhePhe: 2.466 ± 1.224
1.85PheGly: 1.85 ± 0.536
0.154PheHis: 0.154 ± 0.158
4.625PheIle: 4.625 ± 1.204
5.087PheLys: 5.087 ± 0.928
3.237PheLeu: 3.237 ± 0.868
1.079PheMet: 1.079 ± 0.454
3.083PheAsn: 3.083 ± 0.675
2.312PhePro: 2.312 ± 0.584
1.079PheGln: 1.079 ± 0.443
0.925PheArg: 0.925 ± 0.295
1.696PheSer: 1.696 ± 0.509
2.929PheThr: 2.929 ± 0.695
2.004PheVal: 2.004 ± 0.488
0.0PheTrp: 0.0 ± 0.0
2.466PheTyr: 2.466 ± 0.901
0.0PheXaa: 0.0 ± 0.0
Gly
5.55GlyAla: 5.55 ± 2.085
0.462GlyCys: 0.462 ± 0.255
2.158GlyAsp: 2.158 ± 0.567
3.546GlyGlu: 3.546 ± 0.828
2.312GlyPhe: 2.312 ± 0.673
5.241GlyGly: 5.241 ± 1.251
1.079GlyHis: 1.079 ± 0.548
4.625GlyIle: 4.625 ± 0.759
4.47GlyLys: 4.47 ± 0.808
6.629GlyLeu: 6.629 ± 0.872
1.079GlyMet: 1.079 ± 0.378
5.087GlyAsn: 5.087 ± 1.534
0.771GlyPro: 0.771 ± 0.587
1.696GlyGln: 1.696 ± 0.356
2.004GlyArg: 2.004 ± 0.611
4.933GlySer: 4.933 ± 1.117
5.087GlyThr: 5.087 ± 1.142
2.158GlyVal: 2.158 ± 0.569
0.462GlyTrp: 0.462 ± 0.218
1.85GlyTyr: 1.85 ± 0.617
0.0GlyXaa: 0.0 ± 0.0
His
0.308HisAla: 0.308 ± 0.247
0.308HisCys: 0.308 ± 0.21
0.771HisAsp: 0.771 ± 0.354
0.154HisGlu: 0.154 ± 0.166
1.079HisPhe: 1.079 ± 0.361
1.079HisGly: 1.079 ± 0.445
0.154HisHis: 0.154 ± 0.156
0.771HisIle: 0.771 ± 0.391
0.617HisLys: 0.617 ± 0.258
1.696HisLeu: 1.696 ± 0.636
0.154HisMet: 0.154 ± 0.162
1.696HisAsn: 1.696 ± 0.624
0.154HisPro: 0.154 ± 0.17
0.771HisGln: 0.771 ± 0.377
0.617HisArg: 0.617 ± 0.362
0.771HisSer: 0.771 ± 0.371
0.771HisThr: 0.771 ± 0.295
0.154HisVal: 0.154 ± 0.116
0.308HisTrp: 0.308 ± 0.181
0.462HisTyr: 0.462 ± 0.264
0.0HisXaa: 0.0 ± 0.0
Ile
3.546IleAla: 3.546 ± 0.884
0.925IleCys: 0.925 ± 0.441
4.779IleAsp: 4.779 ± 1.128
5.55IleGlu: 5.55 ± 0.918
2.621IlePhe: 2.621 ± 0.831
3.237IleGly: 3.237 ± 1.0
0.925IleHis: 0.925 ± 0.307
6.166IleIle: 6.166 ± 1.351
7.091IleLys: 7.091 ± 1.632
7.091IleLeu: 7.091 ± 0.991
1.696IleMet: 1.696 ± 0.442
6.783IleAsn: 6.783 ± 1.035
2.929IlePro: 2.929 ± 0.718
2.929IleGln: 2.929 ± 0.577
2.929IleArg: 2.929 ± 0.887
4.47IleSer: 4.47 ± 0.673
5.704IleThr: 5.704 ± 0.715
3.391IleVal: 3.391 ± 0.601
0.771IleTrp: 0.771 ± 0.283
4.008IleTyr: 4.008 ± 0.872
0.0IleXaa: 0.0 ± 0.0
Lys
3.391LysAla: 3.391 ± 0.475
1.542LysCys: 1.542 ± 0.587
5.704LysAsp: 5.704 ± 1.301
6.629LysGlu: 6.629 ± 1.441
3.391LysPhe: 3.391 ± 0.865
1.85LysGly: 1.85 ± 0.469
1.233LysHis: 1.233 ± 0.524
6.166LysIle: 6.166 ± 1.447
11.716LysLys: 11.716 ± 2.124
6.937LysLeu: 6.937 ± 1.402
2.004LysMet: 2.004 ± 0.595
6.166LysAsn: 6.166 ± 1.257
2.312LysPro: 2.312 ± 0.645
3.854LysGln: 3.854 ± 0.861
4.316LysArg: 4.316 ± 0.873
4.625LysSer: 4.625 ± 0.855
5.087LysThr: 5.087 ± 0.871
4.008LysVal: 4.008 ± 1.01
1.079LysTrp: 1.079 ± 0.476
5.55LysTyr: 5.55 ± 1.395
0.0LysXaa: 0.0 ± 0.0
Leu
2.929LeuAla: 2.929 ± 0.496
1.696LeuCys: 1.696 ± 0.615
4.008LeuAsp: 4.008 ± 0.816
4.625LeuGlu: 4.625 ± 0.875
3.237LeuPhe: 3.237 ± 0.884
4.625LeuGly: 4.625 ± 1.433
1.233LeuHis: 1.233 ± 0.439
5.395LeuIle: 5.395 ± 0.858
8.324LeuLys: 8.324 ± 1.335
7.091LeuLeu: 7.091 ± 0.796
1.233LeuMet: 1.233 ± 0.426
7.091LeuAsn: 7.091 ± 1.282
3.7LeuPro: 3.7 ± 0.882
3.237LeuGln: 3.237 ± 0.709
3.7LeuArg: 3.7 ± 1.048
6.012LeuSer: 6.012 ± 1.054
6.937LeuThr: 6.937 ± 1.12
3.083LeuVal: 3.083 ± 0.593
0.617LeuTrp: 0.617 ± 0.332
5.55LeuTyr: 5.55 ± 0.923
0.0LeuXaa: 0.0 ± 0.0
Met
1.85MetAla: 1.85 ± 0.654
0.308MetCys: 0.308 ± 0.207
1.387MetAsp: 1.387 ± 0.443
1.233MetGlu: 1.233 ± 0.526
0.925MetPhe: 0.925 ± 0.488
2.312MetGly: 2.312 ± 0.678
0.0MetHis: 0.0 ± 0.0
1.387MetIle: 1.387 ± 0.452
1.85MetLys: 1.85 ± 0.509
2.158MetLeu: 2.158 ± 0.535
0.462MetMet: 0.462 ± 0.372
1.85MetAsn: 1.85 ± 0.489
1.079MetPro: 1.079 ± 0.419
1.387MetGln: 1.387 ± 0.503
0.925MetArg: 0.925 ± 0.419
2.158MetSer: 2.158 ± 0.416
1.542MetThr: 1.542 ± 0.539
0.462MetVal: 0.462 ± 0.284
0.308MetTrp: 0.308 ± 0.209
0.771MetTyr: 0.771 ± 0.461
0.0MetXaa: 0.0 ± 0.0
Asn
3.546AsnAla: 3.546 ± 0.762
1.079AsnCys: 1.079 ± 0.532
4.625AsnAsp: 4.625 ± 0.728
2.929AsnGlu: 2.929 ± 0.668
3.854AsnPhe: 3.854 ± 0.826
4.779AsnGly: 4.779 ± 1.569
0.771AsnHis: 0.771 ± 0.317
8.478AsnIle: 8.478 ± 1.147
5.858AsnLys: 5.858 ± 1.376
6.166AsnLeu: 6.166 ± 0.85
1.542AsnMet: 1.542 ± 0.767
4.933AsnAsn: 4.933 ± 0.931
4.779AsnPro: 4.779 ± 1.273
1.079AsnGln: 1.079 ± 0.343
1.85AsnArg: 1.85 ± 0.563
4.47AsnSer: 4.47 ± 1.029
6.32AsnThr: 6.32 ± 1.228
2.929AsnVal: 2.929 ± 0.636
0.617AsnTrp: 0.617 ± 0.329
3.546AsnTyr: 3.546 ± 0.517
0.0AsnXaa: 0.0 ± 0.0
Pro
2.929ProAla: 2.929 ± 0.697
0.617ProCys: 0.617 ± 0.358
2.621ProAsp: 2.621 ± 0.663
1.387ProGlu: 1.387 ± 0.656
1.85ProPhe: 1.85 ± 0.725
1.387ProGly: 1.387 ± 0.5
0.617ProHis: 0.617 ± 0.284
2.621ProIle: 2.621 ± 0.794
3.391ProLys: 3.391 ± 0.941
4.625ProLeu: 4.625 ± 0.904
0.925ProMet: 0.925 ± 0.493
2.312ProAsn: 2.312 ± 0.472
2.929ProPro: 2.929 ± 0.786
1.542ProGln: 1.542 ± 0.427
0.617ProArg: 0.617 ± 0.258
2.775ProSer: 2.775 ± 0.962
3.237ProThr: 3.237 ± 1.596
2.466ProVal: 2.466 ± 1.075
0.0ProTrp: 0.0 ± 0.0
1.387ProTyr: 1.387 ± 0.366
0.0ProXaa: 0.0 ± 0.0
Gln
2.312GlnAla: 2.312 ± 0.69
0.617GlnCys: 0.617 ± 0.344
0.925GlnAsp: 0.925 ± 0.419
2.312GlnGlu: 2.312 ± 0.645
2.466GlnPhe: 2.466 ± 0.754
1.387GlnGly: 1.387 ± 0.481
0.925GlnHis: 0.925 ± 0.41
2.775GlnIle: 2.775 ± 0.597
2.466GlnLys: 2.466 ± 0.978
3.391GlnLeu: 3.391 ± 0.768
2.004GlnMet: 2.004 ± 0.462
1.85GlnAsn: 1.85 ± 0.944
1.233GlnPro: 1.233 ± 0.436
1.079GlnGln: 1.079 ± 0.531
1.85GlnArg: 1.85 ± 0.56
2.775GlnSer: 2.775 ± 0.673
1.696GlnThr: 1.696 ± 0.524
1.85GlnVal: 1.85 ± 0.566
0.462GlnTrp: 0.462 ± 0.363
2.621GlnTyr: 2.621 ± 1.026
0.0GlnXaa: 0.0 ± 0.0
Arg
1.542ArgAla: 1.542 ± 0.589
0.462ArgCys: 0.462 ± 0.287
1.542ArgAsp: 1.542 ± 0.572
2.158ArgGlu: 2.158 ± 0.616
0.771ArgPhe: 0.771 ± 0.362
2.004ArgGly: 2.004 ± 0.493
0.925ArgHis: 0.925 ± 0.371
2.312ArgIle: 2.312 ± 0.416
3.546ArgLys: 3.546 ± 0.925
2.004ArgLeu: 2.004 ± 0.59
1.233ArgMet: 1.233 ± 0.475
3.7ArgAsn: 3.7 ± 0.761
1.542ArgPro: 1.542 ± 0.776
1.233ArgGln: 1.233 ± 0.406
1.542ArgArg: 1.542 ± 0.473
2.466ArgSer: 2.466 ± 1.371
1.696ArgThr: 1.696 ± 0.449
1.387ArgVal: 1.387 ± 0.367
0.462ArgTrp: 0.462 ± 0.287
2.312ArgTyr: 2.312 ± 0.493
0.0ArgXaa: 0.0 ± 0.0
Ser
3.237SerAla: 3.237 ± 0.892
0.925SerCys: 0.925 ± 0.355
3.546SerAsp: 3.546 ± 0.593
4.316SerGlu: 4.316 ± 1.203
2.466SerPhe: 2.466 ± 0.68
4.779SerGly: 4.779 ± 0.877
1.079SerHis: 1.079 ± 0.318
5.395SerIle: 5.395 ± 1.027
4.933SerLys: 4.933 ± 0.883
6.166SerLeu: 6.166 ± 1.09
1.387SerMet: 1.387 ± 0.305
3.546SerAsn: 3.546 ± 0.873
3.546SerPro: 3.546 ± 0.841
2.775SerGln: 2.775 ± 0.624
2.621SerArg: 2.621 ± 1.259
6.012SerSer: 6.012 ± 2.151
4.47SerThr: 4.47 ± 1.041
3.7SerVal: 3.7 ± 0.657
0.617SerTrp: 0.617 ± 0.256
3.391SerTyr: 3.391 ± 0.784
0.0SerXaa: 0.0 ± 0.0
Thr
5.395ThrAla: 5.395 ± 1.092
0.771ThrCys: 0.771 ± 0.434
2.621ThrAsp: 2.621 ± 0.543
2.929ThrGlu: 2.929 ± 0.639
2.466ThrPhe: 2.466 ± 0.599
6.937ThrGly: 6.937 ± 2.716
0.771ThrHis: 0.771 ± 0.257
5.087ThrIle: 5.087 ± 0.871
4.162ThrLys: 4.162 ± 0.917
4.162ThrLeu: 4.162 ± 1.174
2.158ThrMet: 2.158 ± 0.632
4.162ThrAsn: 4.162 ± 0.841
3.854ThrPro: 3.854 ± 0.706
3.854ThrGln: 3.854 ± 1.08
1.542ThrArg: 1.542 ± 0.46
4.933ThrSer: 4.933 ± 1.111
4.625ThrThr: 4.625 ± 1.321
3.083ThrVal: 3.083 ± 0.763
0.154ThrTrp: 0.154 ± 0.143
3.546ThrTyr: 3.546 ± 0.64
0.0ThrXaa: 0.0 ± 0.0
Val
3.7ValAla: 3.7 ± 0.667
0.462ValCys: 0.462 ± 0.201
3.391ValAsp: 3.391 ± 0.847
2.775ValGlu: 2.775 ± 0.531
1.696ValPhe: 1.696 ± 0.425
4.008ValGly: 4.008 ± 0.974
0.617ValHis: 0.617 ± 0.285
3.391ValIle: 3.391 ± 0.52
2.929ValLys: 2.929 ± 0.577
2.775ValLeu: 2.775 ± 0.815
1.079ValMet: 1.079 ± 0.386
3.854ValAsn: 3.854 ± 0.903
1.542ValPro: 1.542 ± 0.637
1.696ValGln: 1.696 ± 0.612
1.233ValArg: 1.233 ± 0.639
4.162ValSer: 4.162 ± 0.658
0.462ValThr: 0.462 ± 0.463
3.7ValVal: 3.7 ± 0.644
0.308ValTrp: 0.308 ± 0.183
2.466ValTyr: 2.466 ± 0.516
0.0ValXaa: 0.0 ± 0.0
Trp
0.925TrpAla: 0.925 ± 0.425
0.0TrpCys: 0.0 ± 0.0
0.617TrpAsp: 0.617 ± 0.326
0.617TrpGlu: 0.617 ± 0.267
0.308TrpPhe: 0.308 ± 0.207
0.617TrpGly: 0.617 ± 0.273
0.0TrpHis: 0.0 ± 0.0
0.462TrpIle: 0.462 ± 0.202
0.462TrpLys: 0.462 ± 0.209
0.617TrpLeu: 0.617 ± 0.286
0.154TrpMet: 0.154 ± 0.116
1.233TrpAsn: 1.233 ± 0.35
0.154TrpPro: 0.154 ± 0.154
0.308TrpGln: 0.308 ± 0.218
0.154TrpArg: 0.154 ± 0.116
0.462TrpSer: 0.462 ± 0.254
0.617TrpThr: 0.617 ± 0.227
0.308TrpVal: 0.308 ± 0.181
0.0TrpTrp: 0.0 ± 0.0
1.079TrpTyr: 1.079 ± 0.547
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.237TyrAla: 3.237 ± 0.701
0.925TyrCys: 0.925 ± 0.404
2.621TyrAsp: 2.621 ± 0.546
3.391TyrGlu: 3.391 ± 0.831
3.083TyrPhe: 3.083 ± 0.714
2.621TyrGly: 2.621 ± 0.522
0.771TyrHis: 0.771 ± 0.337
3.391TyrIle: 3.391 ± 0.759
5.087TyrLys: 5.087 ± 1.113
3.546TyrLeu: 3.546 ± 0.881
2.621TyrMet: 2.621 ± 0.664
4.933TyrAsn: 4.933 ± 0.927
1.079TyrPro: 1.079 ± 0.42
1.233TyrGln: 1.233 ± 0.518
0.925TyrArg: 0.925 ± 0.312
3.854TyrSer: 3.854 ± 0.963
2.466TyrThr: 2.466 ± 0.455
2.312TyrVal: 2.312 ± 0.616
0.617TyrTrp: 0.617 ± 0.266
3.237TyrTyr: 3.237 ± 0.57
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 26 proteins (6488 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski