Amino acid dipepetide frequency for Dipodomys ordii (Ord s kangaroo rat)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.601AlaAla: 6.601 ± 0.035
1.432AlaCys: 1.432 ± 0.012
2.864AlaAsp: 2.864 ± 0.015
4.651AlaGlu: 4.651 ± 0.026
2.669AlaPhe: 2.669 ± 0.017
4.662AlaGly: 4.662 ± 0.029
1.583AlaHis: 1.583 ± 0.011
2.882AlaIle: 2.882 ± 0.016
3.327AlaLys: 3.327 ± 0.021
7.248AlaLeu: 7.248 ± 0.032
1.535AlaMet: 1.535 ± 0.009
2.021AlaAsn: 2.021 ± 0.012
4.255AlaPro: 4.255 ± 0.03
3.325AlaGln: 3.325 ± 0.022
3.658AlaArg: 3.658 ± 0.023
5.894AlaSer: 5.894 ± 0.031
3.585AlaThr: 3.585 ± 0.02
4.676AlaVal: 4.676 ± 0.023
0.796AlaTrp: 0.796 ± 0.008
1.545AlaTyr: 1.545 ± 0.011
0.004AlaXaa: 0.004 ± 0.0
Cys
1.29CysAla: 1.29 ± 0.013
0.684CysCys: 0.684 ± 0.015
1.011CysAsp: 1.011 ± 0.011
1.238CysGlu: 1.238 ± 0.014
0.86CysPhe: 0.86 ± 0.01
1.712CysGly: 1.712 ± 0.022
0.659CysHis: 0.659 ± 0.008
0.948CysIle: 0.948 ± 0.009
1.115CysLys: 1.115 ± 0.012
2.17CysLeu: 2.17 ± 0.016
0.435CysMet: 0.435 ± 0.005
0.816CysAsn: 0.816 ± 0.01
1.371CysPro: 1.371 ± 0.016
1.086CysGln: 1.086 ± 0.012
1.286CysArg: 1.286 ± 0.012
1.985CysSer: 1.985 ± 0.015
1.101CysThr: 1.101 ± 0.01
1.347CysVal: 1.347 ± 0.011
0.283CysTrp: 0.283 ± 0.005
0.584CysTyr: 0.584 ± 0.007
0.002CysXaa: 0.002 ± 0.0
Asp
2.803AspAla: 2.803 ± 0.018
1.046AspCys: 1.046 ± 0.012
2.597AspAsp: 2.597 ± 0.021
3.322AspGlu: 3.322 ± 0.021
2.112AspPhe: 2.112 ± 0.015
3.213AspGly: 3.213 ± 0.02
1.152AspHis: 1.152 ± 0.009
2.542AspIle: 2.542 ± 0.016
2.435AspLys: 2.435 ± 0.017
4.999AspLeu: 4.999 ± 0.022
1.117AspMet: 1.117 ± 0.009
1.673AspAsn: 1.673 ± 0.013
2.952AspPro: 2.952 ± 0.016
1.827AspGln: 1.827 ± 0.012
2.482AspArg: 2.482 ± 0.018
4.233AspSer: 4.233 ± 0.022
2.515AspThr: 2.515 ± 0.016
2.964AspVal: 2.964 ± 0.022
0.605AspTrp: 0.605 ± 0.007
1.431AspTyr: 1.431 ± 0.011
0.003AspXaa: 0.003 ± 0.0
Glu
5.161GluAla: 5.161 ± 0.031
1.323GluCys: 1.323 ± 0.022
4.424GluAsp: 4.424 ± 0.025
7.964GluGlu: 7.964 ± 0.053
1.999GluPhe: 1.999 ± 0.013
4.138GluGly: 4.138 ± 0.026
1.508GluHis: 1.508 ± 0.012
3.04GluIle: 3.04 ± 0.017
5.238GluLys: 5.238 ± 0.036
6.414GluLeu: 6.414 ± 0.03
1.661GluMet: 1.661 ± 0.011
3.056GluAsn: 3.056 ± 0.018
3.296GluPro: 3.296 ± 0.022
3.166GluGln: 3.166 ± 0.021
3.939GluArg: 3.939 ± 0.027
4.384GluSer: 4.384 ± 0.021
3.314GluThr: 3.314 ± 0.019
4.107GluVal: 4.107 ± 0.023
0.669GluTrp: 0.669 ± 0.007
1.523GluTyr: 1.523 ± 0.015
0.004GluXaa: 0.004 ± 0.001
Phe
1.981PheAla: 1.981 ± 0.012
0.997PheCys: 0.997 ± 0.009
1.649PheAsp: 1.649 ± 0.012
1.933PheGlu: 1.933 ± 0.012
1.677PhePhe: 1.677 ± 0.014
2.237PheGly: 2.237 ± 0.014
1.042PheHis: 1.042 ± 0.008
1.914PheIle: 1.914 ± 0.014
1.717PheLys: 1.717 ± 0.012
4.308PheLeu: 4.308 ± 0.021
0.796PheMet: 0.796 ± 0.009
1.334PheAsn: 1.334 ± 0.012
2.061PhePro: 2.061 ± 0.014
1.776PheGln: 1.776 ± 0.012
1.929PheArg: 1.929 ± 0.017
3.446PheSer: 3.446 ± 0.018
2.054PheThr: 2.054 ± 0.014
2.171PheVal: 2.171 ± 0.015
0.492PheTrp: 0.492 ± 0.006
1.231PheTyr: 1.231 ± 0.011
0.003PheXaa: 0.003 ± 0.0
Gly
4.473GlyAla: 4.473 ± 0.025
1.278GlyCys: 1.278 ± 0.012
3.076GlyAsp: 3.076 ± 0.022
3.991GlyGlu: 3.991 ± 0.029
2.406GlyPhe: 2.406 ± 0.014
4.876GlyGly: 4.876 ± 0.037
1.699GlyHis: 1.699 ± 0.012
2.662GlyIle: 2.662 ± 0.016
3.68GlyLys: 3.68 ± 0.025
5.971GlyLeu: 5.971 ± 0.032
1.293GlyMet: 1.293 ± 0.012
2.353GlyAsn: 2.353 ± 0.017
4.375GlyPro: 4.375 ± 0.049
2.801GlyGln: 2.801 ± 0.021
3.793GlyArg: 3.793 ± 0.021
5.855GlySer: 5.855 ± 0.027
3.604GlyThr: 3.604 ± 0.02
3.496GlyVal: 3.496 ± 0.02
0.786GlyTrp: 0.786 ± 0.009
1.679GlyTyr: 1.679 ± 0.013
0.005GlyXaa: 0.005 ± 0.001
His
1.37HisAla: 1.37 ± 0.01
0.719HisCys: 0.719 ± 0.009
0.867HisAsp: 0.867 ± 0.008
1.295HisGlu: 1.295 ± 0.01
1.106HisPhe: 1.106 ± 0.008
1.561HisGly: 1.561 ± 0.012
0.94HisHis: 0.94 ± 0.01
1.241HisIle: 1.241 ± 0.009
1.255HisLys: 1.255 ± 0.011
2.976HisLeu: 2.976 ± 0.017
0.616HisMet: 0.616 ± 0.007
0.86HisAsn: 0.86 ± 0.008
1.713HisPro: 1.713 ± 0.012
1.353HisGln: 1.353 ± 0.014
1.633HisArg: 1.633 ± 0.012
2.367HisSer: 2.367 ± 0.016
1.558HisThr: 1.558 ± 0.015
1.493HisVal: 1.493 ± 0.013
0.343HisTrp: 0.343 ± 0.005
0.816HisTyr: 0.816 ± 0.008
0.003HisXaa: 0.003 ± 0.0
Ile
2.561IleAla: 2.561 ± 0.017
1.101IleCys: 1.101 ± 0.011
1.927IleAsp: 1.927 ± 0.014
2.495IleGlu: 2.495 ± 0.018
1.982IlePhe: 1.982 ± 0.013
2.155IleGly: 2.155 ± 0.015
1.323IleHis: 1.323 ± 0.012
2.381IleIle: 2.381 ± 0.017
2.518IleLys: 2.518 ± 0.019
4.702IleLeu: 4.702 ± 0.024
1.021IleMet: 1.021 ± 0.01
1.748IleAsn: 1.748 ± 0.011
2.635IlePro: 2.635 ± 0.017
2.277IleGln: 2.277 ± 0.015
2.293IleArg: 2.293 ± 0.012
3.669IleSer: 3.669 ± 0.019
2.551IleThr: 2.551 ± 0.017
2.491IleVal: 2.491 ± 0.018
0.517IleTrp: 0.517 ± 0.007
1.413IleTyr: 1.413 ± 0.01
0.003IleXaa: 0.003 ± 0.001
Lys
3.973LysAla: 3.973 ± 0.023
1.065LysCys: 1.065 ± 0.011
3.092LysAsp: 3.092 ± 0.019
5.004LysGlu: 5.004 ± 0.029
1.695LysPhe: 1.695 ± 0.013
3.153LysGly: 3.153 ± 0.026
1.376LysHis: 1.376 ± 0.013
2.648LysIle: 2.648 ± 0.016
4.656LysLys: 4.656 ± 0.039
5.054LysLeu: 5.054 ± 0.025
1.451LysMet: 1.451 ± 0.011
2.324LysAsn: 2.324 ± 0.019
3.042LysPro: 3.042 ± 0.022
2.568LysGln: 2.568 ± 0.018
3.249LysArg: 3.249 ± 0.019
3.967LysSer: 3.967 ± 0.025
3.038LysThr: 3.038 ± 0.02
3.365LysVal: 3.365 ± 0.024
0.573LysTrp: 0.573 ± 0.008
1.508LysTyr: 1.508 ± 0.016
0.003LysXaa: 0.003 ± 0.0
Leu
6.98LeuAla: 6.98 ± 0.031
2.24LeuCys: 2.24 ± 0.017
4.75LeuAsp: 4.75 ± 0.022
7.141LeuGlu: 7.141 ± 0.032
3.464LeuPhe: 3.464 ± 0.018
6.029LeuGly: 6.029 ± 0.028
2.836LeuHis: 2.836 ± 0.017
3.898LeuIle: 3.898 ± 0.021
5.691LeuLys: 5.691 ± 0.026
11.044LeuLeu: 11.044 ± 0.045
2.057LeuMet: 2.057 ± 0.013
3.473LeuAsn: 3.473 ± 0.019
6.168LeuPro: 6.168 ± 0.036
5.878LeuGln: 5.878 ± 0.03
6.008LeuArg: 6.008 ± 0.029
8.223LeuSer: 8.223 ± 0.032
5.145LeuThr: 5.145 ± 0.023
5.613LeuVal: 5.613 ± 0.026
1.168LeuTrp: 1.168 ± 0.011
2.548LeuTyr: 2.548 ± 0.015
0.008LeuXaa: 0.008 ± 0.001
Met
1.994MetAla: 1.994 ± 0.013
0.408MetCys: 0.408 ± 0.006
1.279MetAsp: 1.279 ± 0.009
1.906MetGlu: 1.906 ± 0.015
0.748MetPhe: 0.748 ± 0.008
1.302MetGly: 1.302 ± 0.011
0.468MetHis: 0.468 ± 0.006
0.842MetIle: 0.842 ± 0.008
1.453MetLys: 1.453 ± 0.011
2.053MetLeu: 2.053 ± 0.013
0.581MetMet: 0.581 ± 0.008
0.896MetAsn: 0.896 ± 0.009
1.101MetPro: 1.101 ± 0.011
0.922MetGln: 0.922 ± 0.008
1.058MetArg: 1.058 ± 0.008
1.625MetSer: 1.625 ± 0.011
1.121MetThr: 1.121 ± 0.009
1.447MetVal: 1.447 ± 0.011
0.236MetTrp: 0.236 ± 0.004
0.629MetTyr: 0.629 ± 0.006
0.001MetXaa: 0.001 ± 0.0
Asn
2.029AsnAla: 2.029 ± 0.011
0.803AsnCys: 0.803 ± 0.009
1.475AsnAsp: 1.475 ± 0.013
2.157AsnGlu: 2.157 ± 0.013
1.477AsnPhe: 1.477 ± 0.012
2.392AsnGly: 2.392 ± 0.018
0.943AsnHis: 0.943 ± 0.008
2.054AsnIle: 2.054 ± 0.013
2.188AsnLys: 2.188 ± 0.015
3.737AsnLeu: 3.737 ± 0.019
0.905AsnMet: 0.905 ± 0.009
1.503AsnAsn: 1.503 ± 0.012
2.229AsnPro: 2.229 ± 0.015
1.681AsnGln: 1.681 ± 0.018
1.807AsnArg: 1.807 ± 0.013
3.098AsnSer: 3.098 ± 0.022
1.994AsnThr: 1.994 ± 0.015
2.141AsnVal: 2.141 ± 0.014
0.443AsnTrp: 0.443 ± 0.006
1.091AsnTyr: 1.091 ± 0.01
0.002AsnXaa: 0.002 ± 0.0
Pro
5.018ProAla: 5.018 ± 0.031
1.177ProCys: 1.177 ± 0.014
2.823ProAsp: 2.823 ± 0.017
4.471ProGlu: 4.471 ± 0.021
1.955ProPhe: 1.955 ± 0.013
5.4ProGly: 5.4 ± 0.061
1.53ProHis: 1.53 ± 0.014
1.9ProIle: 1.9 ± 0.014
2.822ProLys: 2.822 ± 0.02
5.397ProLeu: 5.397 ± 0.025
1.152ProMet: 1.152 ± 0.01
1.85ProAsn: 1.85 ± 0.012
6.366ProPro: 6.366 ± 0.053
2.953ProGln: 2.953 ± 0.023
3.434ProArg: 3.434 ± 0.022
5.834ProSer: 5.834 ± 0.033
3.186ProThr: 3.186 ± 0.023
3.908ProVal: 3.908 ± 0.022
0.699ProTrp: 0.699 ± 0.007
1.508ProTyr: 1.508 ± 0.015
0.005ProXaa: 0.005 ± 0.001
Gln
3.585GlnAla: 3.585 ± 0.024
0.941GlnCys: 0.941 ± 0.011
2.367GlnAsp: 2.367 ± 0.015
3.924GlnGlu: 3.924 ± 0.025
1.339GlnPhe: 1.339 ± 0.01
2.877GlnGly: 2.877 ± 0.021
1.299GlnHis: 1.299 ± 0.011
1.938GlnIle: 1.938 ± 0.012
2.893GlnLys: 2.893 ± 0.021
4.848GlnLeu: 4.848 ± 0.028
1.155GlnMet: 1.155 ± 0.009
1.859GlnAsn: 1.859 ± 0.018
2.938GlnPro: 2.938 ± 0.024
3.179GlnGln: 3.179 ± 0.041
2.964GlnArg: 2.964 ± 0.021
3.2GlnSer: 3.2 ± 0.02
2.317GlnThr: 2.317 ± 0.015
2.873GlnVal: 2.873 ± 0.015
0.527GlnTrp: 0.527 ± 0.007
1.144GlnTyr: 1.144 ± 0.01
0.002GlnXaa: 0.002 ± 0.0
Arg
3.887ArgAla: 3.887 ± 0.022
1.181ArgCys: 1.181 ± 0.012
2.727ArgAsp: 2.727 ± 0.016
3.932ArgGlu: 3.932 ± 0.027
1.835ArgPhe: 1.835 ± 0.013
3.601ArgGly: 3.601 ± 0.023
1.53ArgHis: 1.53 ± 0.012
2.375ArgIle: 2.375 ± 0.014
3.7ArgLys: 3.7 ± 0.024
5.417ArgLeu: 5.417 ± 0.024
1.19ArgMet: 1.19 ± 0.009
2.126ArgAsn: 2.126 ± 0.013
3.391ArgPro: 3.391 ± 0.021
2.606ArgGln: 2.606 ± 0.018
4.402ArgArg: 4.402 ± 0.034
4.255ArgSer: 4.255 ± 0.029
2.827ArgThr: 2.827 ± 0.016
3.11ArgVal: 3.11 ± 0.02
0.683ArgTrp: 0.683 ± 0.008
1.429ArgTyr: 1.429 ± 0.009
0.005ArgXaa: 0.005 ± 0.001
Ser
5.339SerAla: 5.339 ± 0.024
1.869SerCys: 1.869 ± 0.015
3.871SerAsp: 3.871 ± 0.027
5.182SerGlu: 5.182 ± 0.027
3.142SerPhe: 3.142 ± 0.018
5.63SerGly: 5.63 ± 0.027
2.196SerHis: 2.196 ± 0.014
3.241SerIle: 3.241 ± 0.017
4.057SerLys: 4.057 ± 0.023
8.362SerLeu: 8.362 ± 0.031
1.673SerMet: 1.673 ± 0.011
2.689SerAsn: 2.689 ± 0.019
6.211SerPro: 6.211 ± 0.039
3.926SerGln: 3.926 ± 0.025
4.597SerArg: 4.597 ± 0.03
9.659SerSer: 9.659 ± 0.069
4.638SerThr: 4.638 ± 0.037
4.865SerVal: 4.865 ± 0.024
1.073SerTrp: 1.073 ± 0.01
2.131SerTyr: 2.131 ± 0.014
0.005SerXaa: 0.005 ± 0.001
Thr
3.731ThrAla: 3.731 ± 0.019
1.318ThrCys: 1.318 ± 0.014
2.42ThrAsp: 2.42 ± 0.014
3.518ThrGlu: 3.518 ± 0.018
2.129ThrPhe: 2.129 ± 0.014
3.529ThrGly: 3.529 ± 0.02
1.344ThrHis: 1.344 ± 0.012
2.409ThrIle: 2.409 ± 0.017
2.618ThrLys: 2.618 ± 0.017
5.363ThrLeu: 5.363 ± 0.022
1.161ThrMet: 1.161 ± 0.009
1.726ThrAsn: 1.726 ± 0.014
3.708ThrPro: 3.708 ± 0.027
2.36ThrGln: 2.36 ± 0.016
2.443ThrArg: 2.443 ± 0.014
4.723ThrSer: 4.723 ± 0.032
3.09ThrThr: 3.09 ± 0.034
3.863ThrVal: 3.863 ± 0.024
0.691ThrTrp: 0.691 ± 0.01
1.394ThrTyr: 1.394 ± 0.01
0.003ThrXaa: 0.003 ± 0.001
Val
4.23ValAla: 4.23 ± 0.021
1.472ValCys: 1.472 ± 0.013
2.909ValAsp: 2.909 ± 0.019
3.77ValGlu: 3.77 ± 0.023
2.44ValPhe: 2.44 ± 0.016
3.305ValGly: 3.305 ± 0.021
1.583ValHis: 1.583 ± 0.012
2.923ValIle: 2.923 ± 0.02
3.261ValLys: 3.261 ± 0.021
6.371ValLeu: 6.371 ± 0.029
1.342ValMet: 1.342 ± 0.011
2.188ValAsn: 2.188 ± 0.016
3.738ValPro: 3.738 ± 0.02
2.729ValGln: 2.729 ± 0.017
2.979ValArg: 2.979 ± 0.016
4.881ValSer: 4.881 ± 0.022
3.725ValThr: 3.725 ± 0.025
4.025ValVal: 4.025 ± 0.024
0.719ValTrp: 0.719 ± 0.008
1.633ValTyr: 1.633 ± 0.01
0.004ValXaa: 0.004 ± 0.001
Trp
0.793TrpAla: 0.793 ± 0.008
0.24TrpCys: 0.24 ± 0.005
0.637TrpAsp: 0.637 ± 0.008
0.788TrpGlu: 0.788 ± 0.009
0.442TrpPhe: 0.442 ± 0.007
0.718TrpGly: 0.718 ± 0.009
0.303TrpHis: 0.303 ± 0.005
0.546TrpIle: 0.546 ± 0.007
0.796TrpLys: 0.796 ± 0.008
1.254TrpLeu: 1.254 ± 0.011
0.311TrpMet: 0.311 ± 0.004
0.545TrpAsn: 0.545 ± 0.007
0.531TrpPro: 0.531 ± 0.007
0.503TrpGln: 0.503 ± 0.005
0.713TrpArg: 0.713 ± 0.009
0.851TrpSer: 0.851 ± 0.009
0.653TrpThr: 0.653 ± 0.007
0.704TrpVal: 0.704 ± 0.007
0.19TrpTrp: 0.19 ± 0.004
0.326TrpTyr: 0.326 ± 0.005
0.001TrpXaa: 0.001 ± 0.0
Tyr
1.405TyrAla: 1.405 ± 0.011
0.685TyrCys: 0.685 ± 0.007
1.258TyrAsp: 1.258 ± 0.013
1.645TyrGlu: 1.645 ± 0.013
1.267TyrPhe: 1.267 ± 0.011
1.656TyrGly: 1.656 ± 0.013
0.769TyrHis: 0.769 ± 0.008
1.379TyrIle: 1.379 ± 0.012
1.384TyrLys: 1.384 ± 0.015
2.664TyrLeu: 2.664 ± 0.014
0.617TyrMet: 0.617 ± 0.006
1.105TyrAsn: 1.105 ± 0.01
1.303TyrPro: 1.303 ± 0.012
1.246TyrGln: 1.246 ± 0.009
1.54TyrArg: 1.54 ± 0.012
2.203TyrSer: 2.203 ± 0.015
1.519TyrThr: 1.519 ± 0.012
1.565TyrVal: 1.565 ± 0.013
0.352TyrTrp: 0.352 ± 0.006
0.933TyrTyr: 0.933 ± 0.01
0.002TyrXaa: 0.002 ± 0.0
Xaa
0.005XaaAla: 0.005 ± 0.001
0.002XaaCys: 0.002 ± 0.0
0.003XaaAsp: 0.003 ± 0.0
0.004XaaGlu: 0.004 ± 0.0
0.003XaaPhe: 0.003 ± 0.0
0.006XaaGly: 0.006 ± 0.001
0.002XaaHis: 0.002 ± 0.0
0.003XaaIle: 0.003 ± 0.0
0.003XaaLys: 0.003 ± 0.001
0.007XaaLeu: 0.007 ± 0.001
0.001XaaMet: 0.001 ± 0.0
0.003XaaAsn: 0.003 ± 0.001
0.004XaaPro: 0.004 ± 0.001
0.003XaaGln: 0.003 ± 0.001
0.004XaaArg: 0.004 ± 0.001
0.004XaaSer: 0.004 ± 0.001
0.003XaaThr: 0.003 ± 0.0
0.006XaaVal: 0.006 ± 0.001
0.001XaaTrp: 0.001 ± 0.0
0.002XaaTyr: 0.002 ± 0.0
0.012XaaXaa: 0.012 ± 0.002
Statistics based on 26567 proteins (15473226 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski