Amino acid dipepetide frequency for Wuhan spider virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.662AlaAla: 6.662 ± 4.603
0.666AlaCys: 0.666 ± 0.547
1.999AlaAsp: 1.999 ± 1.641
3.331AlaGlu: 3.331 ± 1.012
3.997AlaPhe: 3.997 ± 1.352
6.662AlaGly: 6.662 ± 2.258
0.666AlaHis: 0.666 ± 0.755
4.664AlaIle: 4.664 ± 1.104
3.331AlaLys: 3.331 ± 1.305
3.331AlaLeu: 3.331 ± 0.694
2.665AlaMet: 2.665 ± 1.672
1.332AlaAsn: 1.332 ± 0.726
3.331AlaPro: 3.331 ± 1.345
3.331AlaGln: 3.331 ± 1.012
3.331AlaArg: 3.331 ± 1.129
1.999AlaSer: 1.999 ± 0.834
3.997AlaThr: 3.997 ± 2.036
5.996AlaVal: 5.996 ± 1.034
2.665AlaTrp: 2.665 ± 0.631
4.664AlaTyr: 4.664 ± 1.057
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.666CysAsp: 0.666 ± 0.547
1.332CysGlu: 1.332 ± 0.771
0.0CysPhe: 0.0 ± 0.0
1.999CysGly: 1.999 ± 1.502
0.0CysHis: 0.0 ± 0.0
0.666CysIle: 0.666 ± 0.501
0.666CysLys: 0.666 ± 0.501
1.999CysLeu: 1.999 ± 0.917
0.0CysMet: 0.0 ± 0.0
1.332CysAsn: 1.332 ± 0.497
1.332CysPro: 1.332 ± 0.497
1.332CysGln: 1.332 ± 0.497
1.332CysArg: 1.332 ± 1.001
1.332CysSer: 1.332 ± 0.771
0.666CysThr: 0.666 ± 0.501
0.666CysVal: 0.666 ± 0.501
0.666CysTrp: 0.666 ± 0.501
0.666CysTyr: 0.666 ± 0.755
0.0CysXaa: 0.0 ± 0.0
Asp
3.997AspAla: 3.997 ± 1.136
0.0AspCys: 0.0 ± 0.0
3.997AspAsp: 3.997 ± 1.657
3.331AspGlu: 3.331 ± 0.745
0.0AspPhe: 0.0 ± 0.0
2.665AspGly: 2.665 ± 0.688
1.332AspHis: 1.332 ± 0.689
3.997AspIle: 3.997 ± 0.969
2.665AspLys: 2.665 ± 1.283
4.664AspLeu: 4.664 ± 2.38
0.666AspMet: 0.666 ± 0.547
3.331AspAsn: 3.331 ± 1.145
1.332AspPro: 1.332 ± 0.689
3.331AspGln: 3.331 ± 0.694
1.332AspArg: 1.332 ± 0.845
1.999AspSer: 1.999 ± 0.485
2.665AspThr: 2.665 ± 0.631
3.331AspVal: 3.331 ± 1.339
2.665AspTrp: 2.665 ± 1.235
1.999AspTyr: 1.999 ± 1.506
0.0AspXaa: 0.0 ± 0.0
Glu
2.665GluAla: 2.665 ± 1.453
0.0GluCys: 0.0 ± 0.0
2.665GluAsp: 2.665 ± 0.869
0.666GluGlu: 0.666 ± 0.501
3.331GluPhe: 3.331 ± 0.616
1.332GluGly: 1.332 ± 0.845
2.665GluHis: 2.665 ± 1.427
3.331GluIle: 3.331 ± 1.279
1.332GluLys: 1.332 ± 0.497
4.664GluLeu: 4.664 ± 2.74
0.666GluMet: 0.666 ± 0.547
0.666GluAsn: 0.666 ± 0.501
4.664GluPro: 4.664 ± 1.62
3.997GluGln: 3.997 ± 2.017
4.664GluArg: 4.664 ± 1.933
3.331GluSer: 3.331 ± 1.76
3.997GluThr: 3.997 ± 1.538
3.331GluVal: 3.331 ± 0.511
0.666GluTrp: 0.666 ± 0.501
1.999GluTyr: 1.999 ± 0.562
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.999PheCys: 1.999 ± 0.917
2.665PheAsp: 2.665 ± 0.688
2.665PheGlu: 2.665 ± 2.003
0.666PhePhe: 0.666 ± 0.764
2.665PheGly: 2.665 ± 2.003
0.0PheHis: 0.0 ± 0.0
2.665PheIle: 2.665 ± 0.648
3.331PheLys: 3.331 ± 0.616
1.999PheLeu: 1.999 ± 1.641
0.666PheMet: 0.666 ± 0.547
1.332PheAsn: 1.332 ± 0.771
0.666PhePro: 0.666 ± 0.547
0.666PheGln: 0.666 ± 0.764
2.665PheArg: 2.665 ± 1.672
1.332PheSer: 1.332 ± 0.689
5.996PheThr: 5.996 ± 1.449
1.999PheVal: 1.999 ± 1.052
1.999PheTrp: 1.999 ± 0.956
3.331PheTyr: 3.331 ± 2.015
0.0PheXaa: 0.0 ± 0.0
Gly
4.664GlyAla: 4.664 ± 2.45
2.665GlyCys: 2.665 ± 0.994
1.332GlyAsp: 1.332 ± 1.001
1.332GlyGlu: 1.332 ± 1.001
2.665GlyPhe: 2.665 ± 0.631
2.665GlyGly: 2.665 ± 2.235
1.999GlyHis: 1.999 ± 0.917
5.33GlyIle: 5.33 ± 1.587
1.999GlyLys: 1.999 ± 0.834
6.662GlyLeu: 6.662 ± 1.232
0.666GlyMet: 0.666 ± 0.764
1.332GlyAsn: 1.332 ± 0.771
3.997GlyPro: 3.997 ± 3.282
0.666GlyGln: 0.666 ± 0.501
9.993GlyArg: 9.993 ± 6.929
3.331GlySer: 3.331 ± 1.564
5.33GlyThr: 5.33 ± 2.067
2.665GlyVal: 2.665 ± 1.235
0.0GlyTrp: 0.0 ± 0.0
1.999GlyTyr: 1.999 ± 0.834
0.0GlyXaa: 0.0 ± 0.0
His
2.665HisAla: 2.665 ± 0.869
0.0HisCys: 0.0 ± 0.0
2.665HisAsp: 2.665 ± 0.869
0.666HisGlu: 0.666 ± 0.547
0.0HisPhe: 0.0 ± 0.0
0.666HisGly: 0.666 ± 0.755
0.666HisHis: 0.666 ± 0.547
2.665HisIle: 2.665 ± 2.228
1.999HisLys: 1.999 ± 0.939
1.332HisLeu: 1.332 ± 0.497
0.666HisMet: 0.666 ± 0.755
0.666HisAsn: 0.666 ± 0.547
1.332HisPro: 1.332 ± 0.726
1.332HisGln: 1.332 ± 0.689
3.997HisArg: 3.997 ± 1.669
1.999HisSer: 1.999 ± 0.956
1.999HisThr: 1.999 ± 0.834
0.0HisVal: 0.0 ± 0.0
1.332HisTrp: 1.332 ± 0.689
1.332HisTyr: 1.332 ± 0.497
0.0HisXaa: 0.0 ± 0.0
Ile
7.328IleAla: 7.328 ± 1.77
0.666IleCys: 0.666 ± 0.501
3.331IleAsp: 3.331 ± 1.701
2.665IleGlu: 2.665 ± 0.869
1.332IlePhe: 1.332 ± 0.497
1.999IleGly: 1.999 ± 0.562
0.666IleHis: 0.666 ± 0.755
4.664IleIle: 4.664 ± 2.38
5.33IleLys: 5.33 ± 2.567
3.997IleLeu: 3.997 ± 0.956
0.666IleMet: 0.666 ± 0.547
3.997IleAsn: 3.997 ± 2.356
1.999IlePro: 1.999 ± 1.207
4.664IleGln: 4.664 ± 2.141
1.999IleArg: 1.999 ± 1.387
3.331IleSer: 3.331 ± 2.019
6.662IleThr: 6.662 ± 1.629
5.33IleVal: 5.33 ± 1.223
1.332IleTrp: 1.332 ± 0.845
3.331IleTyr: 3.331 ± 1.906
0.0IleXaa: 0.0 ± 0.0
Lys
4.664LysAla: 4.664 ± 1.302
0.0LysCys: 0.0 ± 0.0
1.999LysAsp: 1.999 ± 0.917
1.332LysGlu: 1.332 ± 0.845
5.33LysPhe: 5.33 ± 3.235
3.331LysGly: 3.331 ± 1.788
1.332LysHis: 1.332 ± 0.689
3.997LysIle: 3.997 ± 1.277
3.331LysLys: 3.331 ± 0.745
4.664LysLeu: 4.664 ± 2.106
2.665LysMet: 2.665 ± 1.542
1.999LysAsn: 1.999 ± 1.452
1.999LysPro: 1.999 ± 1.502
2.665LysGln: 2.665 ± 1.427
3.331LysArg: 3.331 ± 1.074
3.331LysSer: 3.331 ± 1.906
1.999LysThr: 1.999 ± 0.834
1.332LysVal: 1.332 ± 0.726
1.332LysTrp: 1.332 ± 1.094
1.999LysTyr: 1.999 ± 0.834
0.0LysXaa: 0.0 ± 0.0
Leu
5.33LeuAla: 5.33 ± 1.811
1.332LeuCys: 1.332 ± 0.771
3.997LeuAsp: 3.997 ± 0.926
10.66LeuGlu: 10.66 ± 2.752
1.999LeuPhe: 1.999 ± 0.917
5.33LeuGly: 5.33 ± 1.578
1.999LeuHis: 1.999 ± 0.834
3.997LeuIle: 3.997 ± 0.926
4.664LeuLys: 4.664 ± 2.74
7.328LeuLeu: 7.328 ± 2.724
1.332LeuMet: 1.332 ± 0.497
3.997LeuAsn: 3.997 ± 0.956
5.996LeuPro: 5.996 ± 0.487
4.664LeuGln: 4.664 ± 1.289
4.664LeuArg: 4.664 ± 1.009
3.331LeuSer: 3.331 ± 2.176
4.664LeuThr: 4.664 ± 1.136
3.331LeuVal: 3.331 ± 1.279
0.666LeuTrp: 0.666 ± 0.547
4.664LeuTyr: 4.664 ± 2.275
0.0LeuXaa: 0.0 ± 0.0
Met
0.666MetAla: 0.666 ± 0.547
0.0MetCys: 0.0 ± 0.0
0.666MetAsp: 0.666 ± 0.547
1.999MetGlu: 1.999 ± 0.917
2.665MetPhe: 2.665 ± 0.869
0.666MetGly: 0.666 ± 0.547
0.666MetHis: 0.666 ± 0.755
0.666MetIle: 0.666 ± 0.764
1.332MetLys: 1.332 ± 1.094
2.665MetLeu: 2.665 ± 1.486
0.666MetMet: 0.666 ± 0.764
1.999MetAsn: 1.999 ± 1.452
2.665MetPro: 2.665 ± 1.379
1.999MetGln: 1.999 ± 0.485
0.666MetArg: 0.666 ± 0.547
3.331MetSer: 3.331 ± 1.074
0.666MetThr: 0.666 ± 0.547
1.999MetVal: 1.999 ± 0.834
0.0MetTrp: 0.0 ± 0.0
0.666MetTyr: 0.666 ± 0.764
0.0MetXaa: 0.0 ± 0.0
Asn
1.999AsnAla: 1.999 ± 0.485
0.0AsnCys: 0.0 ± 0.0
3.997AsnAsp: 3.997 ± 1.079
1.332AsnGlu: 1.332 ± 0.771
1.999AsnPhe: 1.999 ± 0.562
0.0AsnGly: 0.0 ± 0.0
0.0AsnHis: 0.0 ± 0.0
1.332AsnIle: 1.332 ± 0.726
0.0AsnLys: 0.0 ± 0.0
9.327AsnLeu: 9.327 ± 1.838
0.666AsnMet: 0.666 ± 0.764
0.666AsnAsn: 0.666 ± 0.501
2.665AsnPro: 2.665 ± 1.18
3.331AsnGln: 3.331 ± 1.284
1.332AsnArg: 1.332 ± 0.726
2.665AsnSer: 2.665 ± 1.542
1.332AsnThr: 1.332 ± 1.094
4.664AsnVal: 4.664 ± 1.052
0.666AsnTrp: 0.666 ± 0.764
1.999AsnTyr: 1.999 ± 1.506
0.0AsnXaa: 0.0 ± 0.0
Pro
1.999ProAla: 1.999 ± 1.387
1.332ProCys: 1.332 ± 1.001
2.665ProAsp: 2.665 ± 1.69
2.665ProGlu: 2.665 ± 0.994
1.332ProPhe: 1.332 ± 0.726
3.997ProGly: 3.997 ± 1.079
2.665ProHis: 2.665 ± 0.688
4.664ProIle: 4.664 ± 1.009
3.997ProLys: 3.997 ± 1.124
3.997ProLeu: 3.997 ± 1.64
1.332ProMet: 1.332 ± 0.999
1.332ProAsn: 1.332 ± 0.845
5.33ProPro: 5.33 ± 1.376
3.331ProGln: 3.331 ± 1.708
5.33ProArg: 5.33 ± 1.943
5.33ProSer: 5.33 ± 1.587
0.666ProThr: 0.666 ± 0.501
3.997ProVal: 3.997 ± 1.104
0.0ProTrp: 0.0 ± 0.0
1.999ProTyr: 1.999 ± 0.956
0.0ProXaa: 0.0 ± 0.0
Gln
1.999GlnAla: 1.999 ± 1.387
1.999GlnCys: 1.999 ± 0.485
1.999GlnAsp: 1.999 ± 0.485
1.999GlnGlu: 1.999 ± 0.562
1.999GlnPhe: 1.999 ± 0.562
1.999GlnGly: 1.999 ± 0.485
1.999GlnHis: 1.999 ± 1.748
1.332GlnIle: 1.332 ± 1.094
1.332GlnLys: 1.332 ± 0.497
3.331GlnLeu: 3.331 ± 0.511
0.0GlnMet: 0.0 ± 0.0
2.665GlnAsn: 2.665 ± 1.193
5.33GlnPro: 5.33 ± 2.186
0.666GlnGln: 0.666 ± 0.755
3.331GlnArg: 3.331 ± 0.745
3.997GlnSer: 3.997 ± 1.46
1.999GlnThr: 1.999 ± 1.052
3.997GlnVal: 3.997 ± 1.136
0.666GlnTrp: 0.666 ± 0.755
1.999GlnTyr: 1.999 ± 1.052
0.0GlnXaa: 0.0 ± 0.0
Arg
11.992ArgAla: 11.992 ± 3.136
0.666ArgCys: 0.666 ± 0.755
3.331ArgAsp: 3.331 ± 1.145
3.997ArgGlu: 3.997 ± 1.835
3.331ArgPhe: 3.331 ± 1.775
9.327ArgGly: 9.327 ± 6.165
0.666ArgHis: 0.666 ± 0.501
3.331ArgIle: 3.331 ± 0.694
1.332ArgLys: 1.332 ± 1.001
5.33ArgLeu: 5.33 ± 1.274
3.331ArgMet: 3.331 ± 1.94
0.666ArgAsn: 0.666 ± 0.501
2.665ArgPro: 2.665 ± 1.453
2.665ArgGln: 2.665 ± 1.486
3.997ArgArg: 3.997 ± 0.956
4.664ArgSer: 4.664 ± 1.302
1.332ArgThr: 1.332 ± 1.001
3.997ArgVal: 3.997 ± 0.956
1.332ArgTrp: 1.332 ± 0.726
2.665ArgTyr: 2.665 ± 1.59
0.0ArgXaa: 0.0 ± 0.0
Ser
1.999SerAla: 1.999 ± 0.485
2.665SerCys: 2.665 ± 2.003
3.331SerAsp: 3.331 ± 1.322
0.666SerGlu: 0.666 ± 0.501
3.331SerPhe: 3.331 ± 0.694
5.996SerGly: 5.996 ± 2.679
0.666SerHis: 0.666 ± 0.501
4.664SerIle: 4.664 ± 1.221
3.331SerLys: 3.331 ± 2.195
6.662SerLeu: 6.662 ± 2.726
2.665SerMet: 2.665 ± 1.427
1.332SerAsn: 1.332 ± 1.118
2.665SerPro: 2.665 ± 0.631
1.332SerGln: 1.332 ± 1.118
6.662SerArg: 6.662 ± 2.756
1.332SerSer: 1.332 ± 1.001
3.331SerThr: 3.331 ± 1.145
1.332SerVal: 1.332 ± 0.689
1.332SerTrp: 1.332 ± 0.845
2.665SerTyr: 2.665 ± 0.688
0.0SerXaa: 0.0 ± 0.0
Thr
3.331ThrAla: 3.331 ± 0.511
1.332ThrCys: 1.332 ± 1.001
2.665ThrAsp: 2.665 ± 1.379
3.331ThrGlu: 3.331 ± 1.129
1.999ThrPhe: 1.999 ± 0.562
1.999ThrGly: 1.999 ± 1.502
5.996ThrHis: 5.996 ± 1.285
3.331ThrIle: 3.331 ± 0.694
3.997ThrLys: 3.997 ± 1.669
3.997ThrLeu: 3.997 ± 1.277
1.999ThrMet: 1.999 ± 1.39
1.999ThrAsn: 1.999 ± 0.562
4.664ThrPro: 4.664 ± 0.834
1.332ThrGln: 1.332 ± 0.497
2.665ThrArg: 2.665 ± 0.666
3.331ThrSer: 3.331 ± 1.166
4.664ThrThr: 4.664 ± 2.335
3.331ThrVal: 3.331 ± 1.322
1.332ThrTrp: 1.332 ± 1.094
2.665ThrTyr: 2.665 ± 1.338
0.0ThrXaa: 0.0 ± 0.0
Val
3.331ValAla: 3.331 ± 1.305
0.0ValCys: 0.0 ± 0.0
1.332ValAsp: 1.332 ± 0.689
3.997ValGlu: 3.997 ± 1.128
0.666ValPhe: 0.666 ± 0.501
4.664ValGly: 4.664 ± 0.919
2.665ValHis: 2.665 ± 0.869
6.662ValIle: 6.662 ± 0.628
3.997ValLys: 3.997 ± 1.669
4.664ValLeu: 4.664 ± 1.752
1.332ValMet: 1.332 ± 0.558
3.331ValAsn: 3.331 ± 2.195
3.331ValPro: 3.331 ± 1.339
0.0ValGln: 0.0 ± 0.0
3.331ValArg: 3.331 ± 1.074
3.997ValSer: 3.997 ± 1.46
2.665ValThr: 2.665 ± 2.473
6.662ValVal: 6.662 ± 0.628
1.999ValTrp: 1.999 ± 0.562
1.332ValTyr: 1.332 ± 1.094
0.0ValXaa: 0.0 ± 0.0
Trp
1.332TrpAla: 1.332 ± 0.845
1.332TrpCys: 1.332 ± 1.001
1.332TrpAsp: 1.332 ± 1.51
0.0TrpGlu: 0.0 ± 0.0
1.999TrpPhe: 1.999 ± 1.506
1.332TrpGly: 1.332 ± 0.497
1.332TrpHis: 1.332 ± 0.689
0.666TrpIle: 0.666 ± 0.755
1.332TrpLys: 1.332 ± 0.726
1.999TrpLeu: 1.999 ± 0.917
1.332TrpMet: 1.332 ± 0.771
1.332TrpAsn: 1.332 ± 0.726
0.0TrpPro: 0.0 ± 0.0
1.332TrpGln: 1.332 ± 0.845
1.332TrpArg: 1.332 ± 1.094
0.666TrpSer: 0.666 ± 0.547
1.332TrpThr: 1.332 ± 0.689
0.666TrpVal: 0.666 ± 0.764
0.666TrpTrp: 0.666 ± 0.501
0.666TrpTyr: 0.666 ± 0.547
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.999TyrAla: 1.999 ± 1.207
0.0TyrCys: 0.0 ± 0.0
2.665TyrAsp: 2.665 ± 0.869
2.665TyrGlu: 2.665 ± 0.666
0.666TyrPhe: 0.666 ± 0.764
1.999TyrGly: 1.999 ± 0.562
0.0TyrHis: 0.0 ± 0.0
2.665TyrIle: 2.665 ± 1.235
3.331TyrLys: 3.331 ± 2.195
1.332TyrLeu: 1.332 ± 1.001
1.999TyrMet: 1.999 ± 0.562
4.664TyrAsn: 4.664 ± 0.919
1.999TyrPro: 1.999 ± 0.562
1.999TyrGln: 1.999 ± 1.018
4.664TyrArg: 4.664 ± 1.181
3.331TyrSer: 3.331 ± 0.745
4.664TyrThr: 4.664 ± 1.358
1.332TyrVal: 1.332 ± 0.771
0.666TyrTrp: 0.666 ± 0.547
1.999TyrTyr: 1.999 ± 1.502
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1502 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski