Amino acid dipepetide frequency for Tanticharoenia sakaeratensis NBRC 103193

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.349AlaAla: 17.349 ± 0.178	1.522AlaCys: 1.522 ± 0.041	7.228AlaAsp: 7.228 ± 0.098	6.385AlaGlu: 6.385 ± 0.095	4.362AlaPhe: 4.362 ± 0.07	10.957AlaGly: 10.957 ± 0.107	3.199AlaHis: 3.199 ± 0.06	6.634AlaIle: 6.634 ± 0.082	2.568AlaLys: 2.568 ± 0.059	14.909AlaLeu: 14.909 ± 0.159	3.633AlaMet: 3.633 ± 0.051	2.654AlaAsn: 2.654 ± 0.056	7.029AlaPro: 7.029 ± 0.115	4.604AlaGln: 4.604 ± 0.08	10.906AlaArg: 10.906 ± 0.128	7.102AlaSer: 7.102 ± 0.086	6.668AlaThr: 6.668 ± 0.085	8.545AlaVal: 8.545 ± 0.113	1.851AlaTrp: 1.851 ± 0.052	2.509AlaTyr: 2.509 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	1.41CysAla: 1.41 ± 0.038	0.139CysCys: 0.139 ± 0.011	0.66CysAsp: 0.66 ± 0.028	0.423CysGlu: 0.423 ± 0.024	0.33CysPhe: 0.33 ± 0.019	1.114CysGly: 1.114 ± 0.033	0.257CysHis: 0.257 ± 0.016	0.426CysIle: 0.426 ± 0.022	0.141CysLys: 0.141 ± 0.011	0.933CysLeu: 0.933 ± 0.035	0.169CysMet: 0.169 ± 0.014	0.197CysAsn: 0.197 ± 0.013	0.493CysPro: 0.493 ± 0.021	0.235CysGln: 0.235 ± 0.016	0.683CysArg: 0.683 ± 0.028	0.479CysSer: 0.479 ± 0.022	0.522CysThr: 0.522 ± 0.022	0.797CysVal: 0.797 ± 0.029	0.12CysTrp: 0.12 ± 0.01	0.168CysTyr: 0.168 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	8.275AspAla: 8.275 ± 0.092	0.545AspCys: 0.545 ± 0.025	3.382AspAsp: 3.382 ± 0.069	3.055AspGlu: 3.055 ± 0.057	1.922AspPhe: 1.922 ± 0.048	5.417AspGly: 5.417 ± 0.083	1.572AspHis: 1.572 ± 0.039	2.944AspIle: 2.944 ± 0.056	1.029AspLys: 1.029 ± 0.029	6.111AspLeu: 6.111 ± 0.084	1.505AspMet: 1.505 ± 0.039	1.217AspAsn: 1.217 ± 0.035	3.916AspPro: 3.916 ± 0.065	1.755AspGln: 1.755 ± 0.038	4.744AspArg: 4.744 ± 0.073	2.29AspSer: 2.29 ± 0.057	3.03AspThr: 3.03 ± 0.051	4.455AspVal: 4.455 ± 0.071	1.016AspTrp: 1.016 ± 0.032	1.352AspTyr: 1.352 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	6.621GluAla: 6.621 ± 0.09	0.345GluCys: 0.345 ± 0.019	2.509GluAsp: 2.509 ± 0.055	2.122GluGlu: 2.122 ± 0.055	1.249GluPhe: 1.249 ± 0.038	3.588GluGly: 3.588 ± 0.073	1.218GluHis: 1.218 ± 0.037	2.929GluIle: 2.929 ± 0.061	1.326GluLys: 1.326 ± 0.044	4.059GluLeu: 4.059 ± 0.073	1.194GluMet: 1.194 ± 0.04	1.271GluAsn: 1.271 ± 0.04	2.388GluPro: 2.388 ± 0.048	1.853GluGln: 1.853 ± 0.043	4.412GluArg: 4.412 ± 0.079	2.067GluSer: 2.067 ± 0.049	3.572GluThr: 3.572 ± 0.067	2.814GluVal: 2.814 ± 0.053	0.575GluTrp: 0.575 ± 0.024	0.811GluTyr: 0.811 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.376PheAla: 4.376 ± 0.072	0.449PheCys: 0.449 ± 0.023	2.449PheAsp: 2.449 ± 0.052	1.731PheGlu: 1.731 ± 0.049	1.152PhePhe: 1.152 ± 0.036	3.672PheGly: 3.672 ± 0.069	0.803PheHis: 0.803 ± 0.031	1.305PheIle: 1.305 ± 0.041	0.577PheLys: 0.577 ± 0.025	3.097PheLeu: 3.097 ± 0.054	0.784PheMet: 0.784 ± 0.03	0.897PheAsn: 0.897 ± 0.032	1.528PhePro: 1.528 ± 0.035	0.939PheGln: 0.939 ± 0.033	2.213PheArg: 2.213 ± 0.049	2.236PheSer: 2.236 ± 0.054	1.829PheThr: 1.829 ± 0.048	2.64PheVal: 2.64 ± 0.053	0.537PheTrp: 0.537 ± 0.024	0.841PheTyr: 0.841 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	10.36GlyAla: 10.36 ± 0.116	0.94GlyCys: 0.94 ± 0.031	4.284GlyAsp: 4.284 ± 0.057	3.718GlyGlu: 3.718 ± 0.067	3.461GlyPhe: 3.461 ± 0.065	7.44GlyGly: 7.44 ± 0.115	2.51GlyHis: 2.51 ± 0.055	4.573GlyIle: 4.573 ± 0.077	2.133GlyLys: 2.133 ± 0.047	9.275GlyLeu: 9.275 ± 0.095	2.476GlyMet: 2.476 ± 0.049	2.197GlyAsn: 2.197 ± 0.052	3.972GlyPro: 3.972 ± 0.059	3.069GlyGln: 3.069 ± 0.047	6.775GlyArg: 6.775 ± 0.085	4.772GlySer: 4.772 ± 0.084	5.236GlyThr: 5.236 ± 0.079	6.227GlyVal: 6.227 ± 0.089	1.53GlyTrp: 1.53 ± 0.041	2.206GlyTyr: 2.206 ± 0.055	0.0GlyXaa: 0.0 ± 0.0
His	3.327HisAla: 3.327 ± 0.056	0.247HisCys: 0.247 ± 0.015	1.825HisAsp: 1.825 ± 0.045	1.197HisGlu: 1.197 ± 0.037	0.863HisPhe: 0.863 ± 0.028	2.524HisGly: 2.524 ± 0.049	0.8HisHis: 0.8 ± 0.033	1.027HisIle: 1.027 ± 0.032	0.444HisLys: 0.444 ± 0.02	2.355HisLeu: 2.355 ± 0.044	0.549HisMet: 0.549 ± 0.027	0.54HisAsn: 0.54 ± 0.022	1.68HisPro: 1.68 ± 0.038	0.674HisGln: 0.674 ± 0.027	1.743HisArg: 1.743 ± 0.039	1.006HisSer: 1.006 ± 0.031	1.095HisThr: 1.095 ± 0.033	2.067HisVal: 2.067 ± 0.047	0.426HisTrp: 0.426 ± 0.023	0.65HisTyr: 0.65 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	7.641IleAla: 7.641 ± 0.095	0.535IleCys: 0.535 ± 0.023	3.422IleAsp: 3.422 ± 0.059	3.047IleGlu: 3.047 ± 0.056	1.352IlePhe: 1.352 ± 0.034	5.147IleGly: 5.147 ± 0.079	0.881IleHis: 0.881 ± 0.032	1.714IleIle: 1.714 ± 0.053	0.815IleLys: 0.815 ± 0.029	4.272IleLeu: 4.272 ± 0.071	1.08IleMet: 1.08 ± 0.034	1.217IleAsn: 1.217 ± 0.037	2.362IlePro: 2.362 ± 0.048	1.099IleGln: 1.099 ± 0.03	3.295IleArg: 3.295 ± 0.055	2.72IleSer: 2.72 ± 0.055	2.56IleThr: 2.56 ± 0.053	4.213IleVal: 4.213 ± 0.073	0.616IleTrp: 0.616 ± 0.029	0.953IleTyr: 0.953 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	2.714LysAla: 2.714 ± 0.062	0.109LysCys: 0.109 ± 0.011	1.019LysAsp: 1.019 ± 0.037	0.775LysGlu: 0.775 ± 0.033	0.586LysPhe: 0.586 ± 0.027	1.685LysGly: 1.685 ± 0.039	0.445LysHis: 0.445 ± 0.024	1.164LysIle: 1.164 ± 0.037	0.588LysLys: 0.588 ± 0.031	2.245LysLeu: 2.245 ± 0.054	0.511LysMet: 0.511 ± 0.025	0.496LysAsn: 0.496 ± 0.023	1.498LysPro: 1.498 ± 0.039	0.714LysGln: 0.714 ± 0.03	1.723LysArg: 1.723 ± 0.042	1.282LysSer: 1.282 ± 0.036	1.41LysThr: 1.41 ± 0.043	1.405LysVal: 1.405 ± 0.044	0.247LysTrp: 0.247 ± 0.016	0.403LysTyr: 0.403 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	13.941LeuAla: 13.941 ± 0.142	1.126LeuCys: 1.126 ± 0.036	6.437LeuAsp: 6.437 ± 0.087	4.331LeuGlu: 4.331 ± 0.071	3.498LeuPhe: 3.498 ± 0.067	8.485LeuGly: 8.485 ± 0.096	2.593LeuHis: 2.593 ± 0.058	4.611LeuIle: 4.611 ± 0.073	2.237LeuLys: 2.237 ± 0.056	9.746LeuLeu: 9.746 ± 0.121	2.422LeuMet: 2.422 ± 0.053	2.389LeuAsn: 2.389 ± 0.05	6.328LeuPro: 6.328 ± 0.08	2.843LeuGln: 2.843 ± 0.057	8.134LeuArg: 8.134 ± 0.102	6.993LeuSer: 6.993 ± 0.098	5.771LeuThr: 5.771 ± 0.074	7.08LeuVal: 7.08 ± 0.101	1.284LeuTrp: 1.284 ± 0.038	2.134LeuTyr: 2.134 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	3.219MetAla: 3.219 ± 0.063	0.15MetCys: 0.15 ± 0.013	1.138MetAsp: 1.138 ± 0.034	0.889MetGlu: 0.889 ± 0.029	0.697MetPhe: 0.697 ± 0.026	1.757MetGly: 1.757 ± 0.043	0.545MetHis: 0.545 ± 0.023	1.343MetIle: 1.343 ± 0.037	0.636MetLys: 0.636 ± 0.026	2.715MetLeu: 2.715 ± 0.051	0.668MetMet: 0.668 ± 0.027	0.717MetAsn: 0.717 ± 0.025	1.765MetPro: 1.765 ± 0.039	0.897MetGln: 0.897 ± 0.028	1.988MetArg: 1.988 ± 0.041	1.737MetSer: 1.737 ± 0.041	2.115MetThr: 2.115 ± 0.043	1.686MetVal: 1.686 ± 0.039	0.226MetTrp: 0.226 ± 0.016	0.268MetTyr: 0.268 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.238AsnAla: 3.238 ± 0.058	0.208AsnCys: 0.208 ± 0.015	1.364AsnAsp: 1.364 ± 0.035	0.982AsnGlu: 0.982 ± 0.028	0.846AsnPhe: 0.846 ± 0.035	2.524AsnGly: 2.524 ± 0.055	0.519AsnHis: 0.519 ± 0.025	1.189AsnIle: 1.189 ± 0.034	0.419AsnLys: 0.419 ± 0.023	2.234AsnLeu: 2.234 ± 0.047	0.551AsnMet: 0.551 ± 0.02	0.636AsnAsn: 0.636 ± 0.026	1.695AsnPro: 1.695 ± 0.047	0.694AsnGln: 0.694 ± 0.033	1.63AsnArg: 1.63 ± 0.041	1.082AsnSer: 1.082 ± 0.041	1.37AsnThr: 1.37 ± 0.045	1.84AsnVal: 1.84 ± 0.049	0.413AsnTrp: 0.413 ± 0.02	0.608AsnTyr: 0.608 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	7.051ProAla: 7.051 ± 0.1	0.427ProCys: 0.427 ± 0.019	4.762ProAsp: 4.762 ± 0.08	3.442ProGlu: 3.442 ± 0.066	1.976ProPhe: 1.976 ± 0.045	5.318ProGly: 5.318 ± 0.066	1.41ProHis: 1.41 ± 0.037	2.276ProIle: 2.276 ± 0.047	1.341ProLys: 1.341 ± 0.037	5.081ProLeu: 5.081 ± 0.077	1.34ProMet: 1.34 ± 0.039	1.362ProAsn: 1.362 ± 0.035	3.001ProPro: 3.001 ± 0.062	1.966ProGln: 1.966 ± 0.051	3.412ProArg: 3.412 ± 0.062	3.229ProSer: 3.229 ± 0.056	2.827ProThr: 2.827 ± 0.056	4.605ProVal: 4.605 ± 0.067	0.818ProTrp: 0.818 ± 0.029	1.284ProTyr: 1.284 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	4.723GlnAla: 4.723 ± 0.074	0.221GlnCys: 0.221 ± 0.016	1.752GlnAsp: 1.752 ± 0.034	1.287GlnGlu: 1.287 ± 0.037	1.035GlnPhe: 1.035 ± 0.029	2.54GlnGly: 2.54 ± 0.052	0.751GlnHis: 0.751 ± 0.03	1.914GlnIle: 1.914 ± 0.04	0.787GlnLys: 0.787 ± 0.033	2.572GlnLeu: 2.572 ± 0.056	0.829GlnMet: 0.829 ± 0.029	0.882GlnAsn: 0.882 ± 0.031	1.849GlnPro: 1.849 ± 0.046	1.227GlnGln: 1.227 ± 0.046	2.247GlnArg: 2.247 ± 0.047	1.963GlnSer: 1.963 ± 0.042	2.19GlnThr: 2.19 ± 0.05	2.187GlnVal: 2.187 ± 0.047	0.37GlnTrp: 0.37 ± 0.016	0.69GlnTyr: 0.69 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	9.959ArgAla: 9.959 ± 0.106	0.626ArgCys: 0.626 ± 0.024	4.812ArgAsp: 4.812 ± 0.08	3.752ArgGlu: 3.752 ± 0.072	2.878ArgPhe: 2.878 ± 0.054	5.285ArgGly: 5.285 ± 0.072	2.199ArgHis: 2.199 ± 0.054	4.19ArgIle: 4.19 ± 0.07	1.711ArgLys: 1.711 ± 0.039	8.44ArgLeu: 8.44 ± 0.119	2.033ArgMet: 2.033 ± 0.045	1.95ArgAsn: 1.95 ± 0.048	4.094ArgPro: 4.094 ± 0.067	2.62ArgGln: 2.62 ± 0.049	6.388ArgArg: 6.388 ± 0.098	3.798ArgSer: 3.798 ± 0.062	4.07ArgThr: 4.07 ± 0.063	5.031ArgVal: 5.031 ± 0.068	0.998ArgTrp: 0.998 ± 0.031	1.774ArgTyr: 1.774 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	6.891SerAla: 6.891 ± 0.083	0.471SerCys: 0.471 ± 0.022	3.309SerAsp: 3.309 ± 0.056	2.514SerGlu: 2.514 ± 0.05	2.028SerPhe: 2.028 ± 0.049	5.929SerGly: 5.929 ± 0.083	1.302SerHis: 1.302 ± 0.037	2.577SerIle: 2.577 ± 0.048	1.023SerLys: 1.023 ± 0.031	5.733SerLeu: 5.733 ± 0.08	1.367SerMet: 1.367 ± 0.036	1.306SerAsn: 1.306 ± 0.041	3.104SerPro: 3.104 ± 0.061	1.577SerGln: 1.577 ± 0.036	3.912SerArg: 3.912 ± 0.058	3.084SerSer: 3.084 ± 0.059	2.904SerThr: 2.904 ± 0.07	4.211SerVal: 4.211 ± 0.065	0.815SerTrp: 0.815 ± 0.027	1.288SerTyr: 1.288 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	6.71ThrAla: 6.71 ± 0.084	0.482ThrCys: 0.482 ± 0.022	3.162ThrAsp: 3.162 ± 0.058	2.315ThrGlu: 2.315 ± 0.052	1.882ThrPhe: 1.882 ± 0.044	5.322ThrGly: 5.322 ± 0.071	1.411ThrHis: 1.411 ± 0.038	2.98ThrIle: 2.98 ± 0.05	1.136ThrLys: 1.136 ± 0.038	6.875ThrLeu: 6.875 ± 0.086	1.326ThrMet: 1.326 ± 0.042	1.352ThrAsn: 1.352 ± 0.042	3.974ThrPro: 3.974 ± 0.07	1.749ThrGln: 1.749 ± 0.049	3.828ThrArg: 3.828 ± 0.065	2.886ThrSer: 2.886 ± 0.067	3.333ThrThr: 3.333 ± 0.074	4.168ThrVal: 4.168 ± 0.069	0.76ThrTrp: 0.76 ± 0.029	1.286ThrTyr: 1.286 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	8.918ValAla: 8.918 ± 0.113	0.752ValCys: 0.752 ± 0.027	3.826ValAsp: 3.826 ± 0.064	3.479ValGlu: 3.479 ± 0.072	2.594ValPhe: 2.594 ± 0.051	5.281ValGly: 5.281 ± 0.083	1.61ValHis: 1.61 ± 0.042	3.587ValIle: 3.587 ± 0.06	1.365ValLys: 1.365 ± 0.038	7.9ValLeu: 7.9 ± 0.113	1.925ValMet: 1.925 ± 0.034	1.724ValAsn: 1.724 ± 0.043	4.289ValPro: 4.289 ± 0.064	2.175ValGln: 2.175 ± 0.045	5.323ValArg: 5.323 ± 0.086	4.719ValSer: 4.719 ± 0.076	4.501ValThr: 4.501 ± 0.065	5.726ValVal: 5.726 ± 0.092	1.011ValTrp: 1.011 ± 0.029	1.307ValTyr: 1.307 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.348TrpAla: 1.348 ± 0.035	0.162TrpCys: 0.162 ± 0.013	0.705TrpAsp: 0.705 ± 0.03	0.45TrpGlu: 0.45 ± 0.023	0.546TrpPhe: 0.546 ± 0.024	0.933TrpGly: 0.933 ± 0.029	0.483TrpHis: 0.483 ± 0.022	0.756TrpIle: 0.756 ± 0.03	0.336TrpLys: 0.336 ± 0.019	1.757TrpLeu: 1.757 ± 0.049	0.38TrpMet: 0.38 ± 0.02	0.44TrpAsn: 0.44 ± 0.021	0.814TrpPro: 0.814 ± 0.031	0.616TrpGln: 0.616 ± 0.025	1.427TrpArg: 1.427 ± 0.037	0.889TrpSer: 0.889 ± 0.029	0.811TrpThr: 0.811 ± 0.029	0.785TrpVal: 0.785 ± 0.026	0.249TrpTrp: 0.249 ± 0.015	0.292TrpTyr: 0.292 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.54TyrAla: 2.54 ± 0.047	0.24TyrCys: 0.24 ± 0.018	1.489TyrAsp: 1.489 ± 0.048	1.029TyrGlu: 1.029 ± 0.029	0.801TyrPhe: 0.801 ± 0.031	2.233TyrGly: 2.233 ± 0.056	0.531TyrHis: 0.531 ± 0.024	0.803TyrIle: 0.803 ± 0.027	0.405TyrLys: 0.405 ± 0.021	2.074TyrLeu: 2.074 ± 0.051	0.415TyrMet: 0.415 ± 0.02	0.594TyrAsn: 0.594 ± 0.028	1.149TyrPro: 1.149 ± 0.038	0.713TyrGln: 0.713 ± 0.03	1.824TyrArg: 1.824 ± 0.046	1.008TyrSer: 1.008 ± 0.035	1.126TyrThr: 1.126 ± 0.039	1.531TyrVal: 1.531 ± 0.04	0.319TyrTrp: 0.319 ± 0.016	0.591TyrTyr: 0.591 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3154 proteins (1028729 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---