Amino acid dipepetide frequency for Tilletia controversa (dwarf bunt fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.819AlaAla: 15.819 ± 0.099	0.906AlaCys: 0.906 ± 0.014	5.302AlaAsp: 5.302 ± 0.034	6.024AlaGlu: 6.024 ± 0.045	3.307AlaPhe: 3.307 ± 0.029	8.541AlaGly: 8.541 ± 0.058	2.474AlaHis: 2.474 ± 0.024	3.921AlaIle: 3.921 ± 0.031	4.094AlaLys: 4.094 ± 0.04	9.417AlaLeu: 9.417 ± 0.054	2.021AlaMet: 2.021 ± 0.022	3.128AlaAsn: 3.128 ± 0.028	6.87AlaPro: 6.87 ± 0.06	4.52AlaGln: 4.52 ± 0.035	6.739AlaArg: 6.739 ± 0.04	11.009AlaSer: 11.009 ± 0.072	6.202AlaThr: 6.202 ± 0.044	6.177AlaVal: 6.177 ± 0.04	1.169AlaTrp: 1.169 ± 0.017	2.051AlaTyr: 2.051 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.885CysAla: 0.885 ± 0.014	0.172CysCys: 0.172 ± 0.006	0.504CysAsp: 0.504 ± 0.01	0.414CysGlu: 0.414 ± 0.009	0.39CysPhe: 0.39 ± 0.008	0.732CysGly: 0.732 ± 0.013	0.247CysHis: 0.247 ± 0.007	0.463CysIle: 0.463 ± 0.009	0.386CysLys: 0.386 ± 0.011	0.921CysLeu: 0.921 ± 0.015	0.185CysMet: 0.185 ± 0.006	0.28CysAsn: 0.28 ± 0.008	0.567CysPro: 0.567 ± 0.011	0.317CysGln: 0.317 ± 0.008	0.6CysArg: 0.6 ± 0.012	0.785CysSer: 0.785 ± 0.015	0.562CysThr: 0.562 ± 0.012	0.619CysVal: 0.619 ± 0.013	0.147CysTrp: 0.147 ± 0.005	0.238CysTyr: 0.238 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	5.882AspAla: 5.882 ± 0.039	0.471AspCys: 0.471 ± 0.01	5.432AspAsp: 5.432 ± 0.057	4.794AspGlu: 4.794 ± 0.045	1.802AspPhe: 1.802 ± 0.021	4.722AspGly: 4.722 ± 0.027	1.207AspHis: 1.207 ± 0.016	2.23AspIle: 2.23 ± 0.021	1.832AspLys: 1.832 ± 0.023	4.661AspLeu: 4.661 ± 0.033	0.966AspMet: 0.966 ± 0.014	1.463AspAsn: 1.463 ± 0.014	3.332AspPro: 3.332 ± 0.027	1.849AspGln: 1.849 ± 0.018	3.213AspArg: 3.213 ± 0.035	4.137AspSer: 4.137 ± 0.032	2.567AspThr: 2.567 ± 0.023	3.654AspVal: 3.654 ± 0.034	0.754AspTrp: 0.754 ± 0.013	1.107AspTyr: 1.107 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.988GluAla: 5.988 ± 0.045	0.463GluCys: 0.463 ± 0.011	4.377GluAsp: 4.377 ± 0.043	5.707GluGlu: 5.707 ± 0.06	1.384GluPhe: 1.384 ± 0.018	4.223GluGly: 4.223 ± 0.036	1.425GluHis: 1.425 ± 0.017	2.065GluIle: 2.065 ± 0.024	2.593GluLys: 2.593 ± 0.03	5.05GluLeu: 5.05 ± 0.038	1.181GluMet: 1.181 ± 0.016	1.513GluAsn: 1.513 ± 0.018	2.539GluPro: 2.539 ± 0.027	2.537GluGln: 2.537 ± 0.023	4.44GluArg: 4.44 ± 0.039	3.637GluSer: 3.637 ± 0.028	2.624GluThr: 2.624 ± 0.024	3.287GluVal: 3.287 ± 0.031	0.746GluTrp: 0.746 ± 0.012	1.135GluTyr: 1.135 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	3.093PheAla: 3.093 ± 0.025	0.413PheCys: 0.413 ± 0.009	2.032PheAsp: 2.032 ± 0.022	1.753PheGlu: 1.753 ± 0.021	1.268PhePhe: 1.268 ± 0.018	2.735PheGly: 2.735 ± 0.032	0.794PheHis: 0.794 ± 0.011	1.239PheIle: 1.239 ± 0.018	1.157PheLys: 1.157 ± 0.019	2.904PheLeu: 2.904 ± 0.031	0.52PheMet: 0.52 ± 0.009	1.06PheAsn: 1.06 ± 0.014	1.723PhePro: 1.723 ± 0.016	1.136PheGln: 1.136 ± 0.015	1.824PheArg: 1.824 ± 0.018	2.747PheSer: 2.747 ± 0.023	1.725PheThr: 1.725 ± 0.02	2.099PheVal: 2.099 ± 0.02	0.458PheTrp: 0.458 ± 0.01	0.736PheTyr: 0.736 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	7.95GlyAla: 7.95 ± 0.054	0.688GlyCys: 0.688 ± 0.012	3.771GlyAsp: 3.771 ± 0.033	3.808GlyGlu: 3.808 ± 0.037	2.341GlyPhe: 2.341 ± 0.025	9.409GlyGly: 9.409 ± 0.115	1.801GlyHis: 1.801 ± 0.021	2.786GlyIle: 2.786 ± 0.023	3.373GlyLys: 3.373 ± 0.033	5.956GlyLeu: 5.956 ± 0.038	1.687GlyMet: 1.687 ± 0.026	2.411GlyAsn: 2.411 ± 0.026	4.586GlyPro: 4.586 ± 0.044	2.866GlyGln: 2.866 ± 0.033	4.821GlyArg: 4.821 ± 0.036	7.955GlySer: 7.955 ± 0.07	4.591GlyThr: 4.591 ± 0.038	4.342GlyVal: 4.342 ± 0.033	1.03GlyTrp: 1.03 ± 0.015	1.617GlyTyr: 1.617 ± 0.024	0.001GlyXaa: 0.001 ± 0.0
His	2.489HisAla: 2.489 ± 0.024	0.266HisCys: 0.266 ± 0.008	1.28HisAsp: 1.28 ± 0.016	1.168HisGlu: 1.168 ± 0.015	0.904HisPhe: 0.904 ± 0.014	1.794HisGly: 1.794 ± 0.022	1.188HisHis: 1.188 ± 0.027	1.015HisIle: 1.015 ± 0.017	0.775HisLys: 0.775 ± 0.014	2.348HisLeu: 2.348 ± 0.023	0.41HisMet: 0.41 ± 0.009	0.744HisAsn: 0.744 ± 0.012	1.895HisPro: 1.895 ± 0.026	1.305HisGln: 1.305 ± 0.024	1.688HisArg: 1.688 ± 0.019	2.104HisSer: 2.104 ± 0.025	1.335HisThr: 1.335 ± 0.017	1.383HisVal: 1.383 ± 0.018	0.313HisTrp: 0.313 ± 0.008	0.507HisTyr: 0.507 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	3.76IleAla: 3.76 ± 0.027	0.491IleCys: 0.491 ± 0.011	2.379IleAsp: 2.379 ± 0.025	2.211IleGlu: 2.211 ± 0.025	1.416IlePhe: 1.416 ± 0.022	2.633IleGly: 2.633 ± 0.024	0.944IleHis: 0.944 ± 0.015	1.667IleIle: 1.667 ± 0.022	1.666IleLys: 1.666 ± 0.021	3.492IleLeu: 3.492 ± 0.032	0.701IleMet: 0.701 ± 0.012	1.243IleAsn: 1.243 ± 0.016	2.5IlePro: 2.5 ± 0.022	1.491IleGln: 1.491 ± 0.017	2.538IleArg: 2.538 ± 0.023	3.11IleSer: 3.11 ± 0.026	2.131IleThr: 2.131 ± 0.025	2.548IleVal: 2.548 ± 0.025	0.491IleTrp: 0.491 ± 0.01	0.882IleTyr: 0.882 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.403LysAla: 4.403 ± 0.043	0.338LysCys: 0.338 ± 0.009	2.261LysAsp: 2.261 ± 0.021	2.729LysGlu: 2.729 ± 0.034	0.982LysPhe: 0.982 ± 0.015	2.897LysGly: 2.897 ± 0.032	0.966LysHis: 0.966 ± 0.015	1.546LysIle: 1.546 ± 0.019	2.781LysLys: 2.781 ± 0.039	3.306LysLeu: 3.306 ± 0.03	0.8LysMet: 0.8 ± 0.013	1.26LysAsn: 1.26 ± 0.016	2.098LysPro: 2.098 ± 0.026	1.6LysGln: 1.6 ± 0.018	3.256LysArg: 3.256 ± 0.031	2.764LysSer: 2.764 ± 0.025	2.362LysThr: 2.362 ± 0.023	2.418LysVal: 2.418 ± 0.025	0.487LysTrp: 0.487 ± 0.009	0.885LysTyr: 0.885 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	9.044LeuAla: 9.044 ± 0.051	1.014LeuCys: 1.014 ± 0.015	4.98LeuAsp: 4.98 ± 0.034	4.736LeuGlu: 4.736 ± 0.037	2.838LeuPhe: 2.838 ± 0.026	6.11LeuGly: 6.11 ± 0.037	2.204LeuHis: 2.204 ± 0.019	3.175LeuIle: 3.175 ± 0.036	3.354LeuLys: 3.354 ± 0.029	8.353LeuLeu: 8.353 ± 0.058	1.452LeuMet: 1.452 ± 0.018	2.725LeuAsn: 2.725 ± 0.025	6.256LeuPro: 6.256 ± 0.037	3.632LeuGln: 3.632 ± 0.034	6.354LeuArg: 6.354 ± 0.037	7.634LeuSer: 7.634 ± 0.041	4.638LeuThr: 4.638 ± 0.032	5.101LeuVal: 5.101 ± 0.039	0.966LeuTrp: 0.966 ± 0.014	1.782LeuTyr: 1.782 ± 0.02	0.0LeuXaa: 0.0 ± 0.0
Met	1.996MetAla: 1.996 ± 0.02	0.181MetCys: 0.181 ± 0.006	1.103MetAsp: 1.103 ± 0.015	1.025MetGlu: 1.025 ± 0.014	0.541MetPhe: 0.541 ± 0.01	1.434MetGly: 1.434 ± 0.021	0.427MetHis: 0.427 ± 0.01	0.658MetIle: 0.658 ± 0.011	0.663MetLys: 0.663 ± 0.011	1.713MetLeu: 1.713 ± 0.019	0.488MetMet: 0.488 ± 0.013	0.595MetAsn: 0.595 ± 0.012	1.236MetPro: 1.236 ± 0.018	0.774MetGln: 0.774 ± 0.013	1.299MetArg: 1.299 ± 0.016	1.837MetSer: 1.837 ± 0.021	1.091MetThr: 1.091 ± 0.015	1.056MetVal: 1.056 ± 0.012	0.19MetTrp: 0.19 ± 0.006	0.374MetTyr: 0.374 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.324AsnAla: 3.324 ± 0.027	0.279AsnCys: 0.279 ± 0.008	1.601AsnAsp: 1.601 ± 0.017	1.593AsnGlu: 1.593 ± 0.016	1.002AsnPhe: 1.002 ± 0.016	2.9AsnGly: 2.9 ± 0.031	0.693AsnHis: 0.693 ± 0.011	1.295AsnIle: 1.295 ± 0.02	1.225AsnLys: 1.225 ± 0.017	2.606AsnLeu: 2.606 ± 0.026	0.591AsnMet: 0.591 ± 0.011	1.337AsnAsn: 1.337 ± 0.022	2.071AsnPro: 2.071 ± 0.02	1.071AsnGln: 1.071 ± 0.015	1.726AsnArg: 1.726 ± 0.017	2.583AsnSer: 2.583 ± 0.027	1.829AsnThr: 1.829 ± 0.021	1.898AsnVal: 1.898 ± 0.021	0.362AsnTrp: 0.362 ± 0.009	0.648AsnTyr: 0.648 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	7.568ProAla: 7.568 ± 0.061	0.434ProCys: 0.434 ± 0.01	2.97ProAsp: 2.97 ± 0.025	3.092ProGlu: 3.092 ± 0.024	2.022ProPhe: 2.022 ± 0.02	4.487ProGly: 4.487 ± 0.047	1.574ProHis: 1.574 ± 0.02	2.312ProIle: 2.312 ± 0.022	2.117ProLys: 2.117 ± 0.026	5.073ProLeu: 5.073 ± 0.038	1.028ProMet: 1.028 ± 0.017	1.96ProAsn: 1.96 ± 0.022	6.356ProPro: 6.356 ± 0.074	2.456ProGln: 2.456 ± 0.029	3.702ProArg: 3.702 ± 0.027	8.018ProSer: 8.018 ± 0.055	4.748ProThr: 4.748 ± 0.039	3.7ProVal: 3.7 ± 0.027	0.603ProTrp: 0.603 ± 0.011	1.248ProTyr: 1.248 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	4.354GlnAla: 4.354 ± 0.037	0.329GlnCys: 0.329 ± 0.01	2.079GlnAsp: 2.079 ± 0.023	2.22GlnGlu: 2.22 ± 0.024	0.979GlnPhe: 0.979 ± 0.015	2.709GlnGly: 2.709 ± 0.032	1.569GlnHis: 1.569 ± 0.027	1.431GlnIle: 1.431 ± 0.018	1.492GlnLys: 1.492 ± 0.017	3.607GlnLeu: 3.607 ± 0.029	0.768GlnMet: 0.768 ± 0.013	1.179GlnAsn: 1.179 ± 0.019	2.778GlnPro: 2.778 ± 0.03	4.558GlnGln: 4.558 ± 0.116	3.06GlnArg: 3.06 ± 0.028	3.109GlnSer: 3.109 ± 0.033	2.206GlnThr: 2.206 ± 0.022	2.138GlnVal: 2.138 ± 0.022	0.429GlnTrp: 0.429 ± 0.011	0.859GlnTyr: 0.859 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	6.706ArgAla: 6.706 ± 0.04	0.646ArgCys: 0.646 ± 0.011	3.231ArgAsp: 3.231 ± 0.032	3.734ArgGlu: 3.734 ± 0.04	2.137ArgPhe: 2.137 ± 0.02	4.087ArgGly: 4.087 ± 0.04	1.614ArgHis: 1.614 ± 0.018	2.783ArgIle: 2.783 ± 0.024	3.263ArgLys: 3.263 ± 0.031	5.893ArgLeu: 5.893 ± 0.043	1.355ArgMet: 1.355 ± 0.019	2.026ArgAsn: 2.026 ± 0.021	4.169ArgPro: 4.169 ± 0.035	2.779ArgGln: 2.779 ± 0.027	5.994ArgArg: 5.994 ± 0.047	6.077ArgSer: 6.077 ± 0.048	4.028ArgThr: 4.028 ± 0.028	3.53ArgVal: 3.53 ± 0.03	0.899ArgTrp: 0.899 ± 0.014	1.405ArgTyr: 1.405 ± 0.018	0.001ArgXaa: 0.001 ± 0.0
Ser	10.737SerAla: 10.737 ± 0.075	0.68SerCys: 0.68 ± 0.012	4.439SerAsp: 4.439 ± 0.035	3.907SerGlu: 3.907 ± 0.028	2.908SerPhe: 2.908 ± 0.026	7.408SerGly: 7.408 ± 0.072	2.1SerHis: 2.1 ± 0.022	3.487SerIle: 3.487 ± 0.028	3.476SerLys: 3.476 ± 0.033	7.266SerLeu: 7.266 ± 0.046	1.739SerMet: 1.739 ± 0.023	3.028SerAsn: 3.028 ± 0.032	6.342SerPro: 6.342 ± 0.055	3.351SerGln: 3.351 ± 0.029	5.584SerArg: 5.584 ± 0.04	14.747SerSer: 14.747 ± 0.124	7.249SerThr: 7.249 ± 0.062	4.879SerVal: 4.879 ± 0.038	0.892SerTrp: 0.892 ± 0.014	1.68SerTyr: 1.68 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	6.853ThrAla: 6.853 ± 0.043	0.559ThrCys: 0.559 ± 0.012	2.754ThrAsp: 2.754 ± 0.025	2.635ThrGlu: 2.635 ± 0.021	2.041ThrPhe: 2.041 ± 0.019	4.294ThrGly: 4.294 ± 0.039	1.33ThrHis: 1.33 ± 0.016	2.476ThrIle: 2.476 ± 0.023	2.165ThrLys: 2.165 ± 0.026	5.082ThrLeu: 5.082 ± 0.031	1.088ThrMet: 1.088 ± 0.015	1.805ThrAsn: 1.805 ± 0.018	4.554ThrPro: 4.554 ± 0.041	1.978ThrGln: 1.978 ± 0.022	3.292ThrArg: 3.292 ± 0.025	6.606ThrSer: 6.606 ± 0.059	4.78ThrThr: 4.78 ± 0.057	3.433ThrVal: 3.433 ± 0.027	0.66ThrTrp: 0.66 ± 0.011	1.221ThrTyr: 1.221 ± 0.016	0.001ThrXaa: 0.001 ± 0.0
Val	5.755ValAla: 5.755 ± 0.04	0.668ValCys: 0.668 ± 0.012	3.598ValAsp: 3.598 ± 0.03	3.577ValGlu: 3.577 ± 0.032	1.979ValPhe: 1.979 ± 0.022	4.297ValGly: 4.297 ± 0.036	1.432ValHis: 1.432 ± 0.017	2.3ValIle: 2.3 ± 0.024	2.428ValLys: 2.428 ± 0.024	5.656ValLeu: 5.656 ± 0.037	1.048ValMet: 1.048 ± 0.014	1.713ValAsn: 1.713 ± 0.02	3.928ValPro: 3.928 ± 0.028	2.374ValGln: 2.374 ± 0.022	3.988ValArg: 3.988 ± 0.029	4.559ValSer: 4.559 ± 0.036	2.996ValThr: 2.996 ± 0.028	3.953ValVal: 3.953 ± 0.032	0.743ValTrp: 0.743 ± 0.013	1.224ValTyr: 1.224 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	1.101TrpAla: 1.101 ± 0.014	0.155TrpCys: 0.155 ± 0.006	0.717TrpAsp: 0.717 ± 0.012	0.641TrpGlu: 0.641 ± 0.012	0.37TrpPhe: 0.37 ± 0.008	0.684TrpGly: 0.684 ± 0.013	0.332TrpHis: 0.332 ± 0.009	0.548TrpIle: 0.548 ± 0.011	0.561TrpLys: 0.561 ± 0.011	1.104TrpLeu: 1.104 ± 0.017	0.264TrpMet: 0.264 ± 0.007	0.457TrpAsn: 0.457 ± 0.01	0.561TrpPro: 0.561 ± 0.011	0.457TrpGln: 0.457 ± 0.01	0.898TrpArg: 0.898 ± 0.014	0.953TrpSer: 0.953 ± 0.015	0.812TrpThr: 0.812 ± 0.014	0.717TrpVal: 0.717 ± 0.014	0.217TrpTrp: 0.217 ± 0.007	0.283TrpTyr: 0.283 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.986TyrAla: 1.986 ± 0.022	0.263TyrCys: 0.263 ± 0.008	1.265TyrAsp: 1.265 ± 0.017	1.148TyrGlu: 1.148 ± 0.014	0.804TyrPhe: 0.804 ± 0.013	1.69TyrGly: 1.69 ± 0.024	0.591TyrHis: 0.591 ± 0.014	0.897TyrIle: 0.897 ± 0.013	0.737TyrLys: 0.737 ± 0.013	1.94TyrLeu: 1.94 ± 0.021	0.388TyrMet: 0.388 ± 0.008	0.706TyrAsn: 0.706 ± 0.012	1.108TyrPro: 1.108 ± 0.016	0.801TyrGln: 0.801 ± 0.013	1.342TyrArg: 1.342 ± 0.017	1.527TyrSer: 1.527 ± 0.021	1.13TyrThr: 1.13 ± 0.017	1.282TyrVal: 1.282 ± 0.017	0.278TyrTrp: 0.278 ± 0.007	0.555TyrTyr: 0.555 ± 0.011	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.01XaaXaa: 0.01 ± 0.004

Statistics based on 9854 proteins (5235128 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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