Amino acid dipepetide frequency for Abditibacterium utsteinense

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.127AlaAla: 13.127 ± 0.159	0.865AlaCys: 0.865 ± 0.028	4.763AlaAsp: 4.763 ± 0.079	5.174AlaGlu: 5.174 ± 0.079	4.186AlaPhe: 4.186 ± 0.072	8.159AlaGly: 8.159 ± 0.094	2.166AlaHis: 2.166 ± 0.048	5.56AlaIle: 5.56 ± 0.078	4.706AlaLys: 4.706 ± 0.079	13.0AlaLeu: 13.0 ± 0.15	2.39AlaMet: 2.39 ± 0.046	3.142AlaAsn: 3.142 ± 0.062	6.937AlaPro: 6.937 ± 0.116	5.755AlaGln: 5.755 ± 0.098	8.697AlaArg: 8.697 ± 0.143	6.447AlaSer: 6.447 ± 0.09	5.988AlaThr: 5.988 ± 0.083	6.5AlaVal: 6.5 ± 0.082	1.348AlaTrp: 1.348 ± 0.038	2.03AlaTyr: 2.03 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	1.177CysAla: 1.177 ± 0.037	0.173CysCys: 0.173 ± 0.013	0.642CysAsp: 0.642 ± 0.028	0.578CysGlu: 0.578 ± 0.024	0.438CysPhe: 0.438 ± 0.017	1.09CysGly: 1.09 ± 0.037	0.215CysHis: 0.215 ± 0.016	0.411CysIle: 0.411 ± 0.019	0.259CysLys: 0.259 ± 0.016	0.848CysLeu: 0.848 ± 0.033	0.098CysMet: 0.098 ± 0.01	0.298CysAsn: 0.298 ± 0.018	0.506CysPro: 0.506 ± 0.023	0.315CysGln: 0.315 ± 0.016	0.554CysArg: 0.554 ± 0.022	0.496CysSer: 0.496 ± 0.025	0.337CysThr: 0.337 ± 0.023	0.607CysVal: 0.607 ± 0.027	0.095CysTrp: 0.095 ± 0.009	0.225CysTyr: 0.225 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	6.586AspAla: 6.586 ± 0.095	0.419AspCys: 0.419 ± 0.021	2.61AspAsp: 2.61 ± 0.053	3.705AspGlu: 3.705 ± 0.072	2.828AspPhe: 2.828 ± 0.06	4.284AspGly: 4.284 ± 0.072	0.707AspHis: 0.707 ± 0.024	2.381AspIle: 2.381 ± 0.053	2.02AspLys: 2.02 ± 0.052	5.264AspLeu: 5.264 ± 0.088	0.806AspMet: 0.806 ± 0.027	1.538AspAsn: 1.538 ± 0.042	2.172AspPro: 2.172 ± 0.05	1.228AspGln: 1.228 ± 0.036	2.123AspArg: 2.123 ± 0.046	2.825AspSer: 2.825 ± 0.052	2.176AspThr: 2.176 ± 0.048	3.596AspVal: 3.596 ± 0.062	0.85AspTrp: 0.85 ± 0.031	1.424AspTyr: 1.424 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	6.589GluAla: 6.589 ± 0.099	0.383GluCys: 0.383 ± 0.02	2.367GluAsp: 2.367 ± 0.046	3.579GluGlu: 3.579 ± 0.082	2.249GluPhe: 2.249 ± 0.048	3.701GluGly: 3.701 ± 0.07	0.975GluHis: 0.975 ± 0.033	4.825GluIle: 4.825 ± 0.081	3.606GluLys: 3.606 ± 0.067	5.616GluLeu: 5.616 ± 0.072	1.66GluMet: 1.66 ± 0.044	3.128GluAsn: 3.128 ± 0.05	2.122GluPro: 2.122 ± 0.051	1.828GluGln: 1.828 ± 0.049	4.071GluArg: 4.071 ± 0.074	3.621GluSer: 3.621 ± 0.054	3.916GluThr: 3.916 ± 0.062	4.21GluVal: 4.21 ± 0.075	0.845GluTrp: 0.845 ± 0.029	1.016GluTyr: 1.016 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	4.557PheAla: 4.557 ± 0.073	0.685PheCys: 0.685 ± 0.03	2.792PheAsp: 2.792 ± 0.054	2.771PheGlu: 2.771 ± 0.05	1.987PhePhe: 1.987 ± 0.05	3.902PheGly: 3.902 ± 0.067	0.832PheHis: 0.832 ± 0.029	1.816PheIle: 1.816 ± 0.042	1.417PheLys: 1.417 ± 0.041	4.36PheLeu: 4.36 ± 0.065	0.662PheMet: 0.662 ± 0.026	1.435PheAsn: 1.435 ± 0.037	2.185PhePro: 2.185 ± 0.048	1.401PheGln: 1.401 ± 0.038	2.222PheArg: 2.222 ± 0.048	3.284PheSer: 3.284 ± 0.058	1.942PheThr: 1.942 ± 0.048	2.987PheVal: 2.987 ± 0.049	0.843PheTrp: 0.843 ± 0.03	1.17PheTyr: 1.17 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	9.897GlyAla: 9.897 ± 0.124	0.793GlyCys: 0.793 ± 0.029	4.158GlyAsp: 4.158 ± 0.067	5.04GlyGlu: 5.04 ± 0.067	3.651GlyPhe: 3.651 ± 0.063	6.813GlyGly: 6.813 ± 0.123	1.638GlyHis: 1.638 ± 0.045	4.238GlyIle: 4.238 ± 0.059	3.777GlyLys: 3.777 ± 0.068	7.004GlyLeu: 7.004 ± 0.089	1.578GlyMet: 1.578 ± 0.048	2.687GlyAsn: 2.687 ± 0.049	2.585GlyPro: 2.585 ± 0.055	3.243GlyGln: 3.243 ± 0.057	4.716GlyArg: 4.716 ± 0.07	4.252GlySer: 4.252 ± 0.073	4.245GlyThr: 4.245 ± 0.078	5.618GlyVal: 5.618 ± 0.076	1.204GlyTrp: 1.204 ± 0.036	1.957GlyTyr: 1.957 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.764HisAla: 1.764 ± 0.039	0.227HisCys: 0.227 ± 0.015	0.974HisAsp: 0.974 ± 0.033	1.075HisGlu: 1.075 ± 0.031	1.182HisPhe: 1.182 ± 0.034	1.443HisGly: 1.443 ± 0.04	0.527HisHis: 0.527 ± 0.027	0.986HisIle: 0.986 ± 0.028	0.615HisLys: 0.615 ± 0.021	2.199HisLeu: 2.199 ± 0.045	0.268HisMet: 0.268 ± 0.016	0.59HisAsn: 0.59 ± 0.023	1.149HisPro: 1.149 ± 0.036	0.69HisGln: 0.69 ± 0.029	1.202HisArg: 1.202 ± 0.032	1.163HisSer: 1.163 ± 0.036	0.762HisThr: 0.762 ± 0.029	1.15HisVal: 1.15 ± 0.033	0.291HisTrp: 0.291 ± 0.017	0.488HisTyr: 0.488 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	6.467IleAla: 6.467 ± 0.089	0.633IleCys: 0.633 ± 0.024	2.765IleAsp: 2.765 ± 0.052	4.234IleGlu: 4.234 ± 0.081	2.285IlePhe: 2.285 ± 0.042	4.629IleGly: 4.629 ± 0.069	0.903IleHis: 0.903 ± 0.032	2.301IleIle: 2.301 ± 0.051	1.848IleLys: 1.848 ± 0.044	5.188IleLeu: 5.188 ± 0.076	0.748IleMet: 0.748 ± 0.032	1.615IleAsn: 1.615 ± 0.041	2.533IlePro: 2.533 ± 0.049	1.599IleGln: 1.599 ± 0.038	2.43IleArg: 2.43 ± 0.048	3.743IleSer: 3.743 ± 0.064	2.49IleThr: 2.49 ± 0.047	3.808IleVal: 3.808 ± 0.064	0.711IleTrp: 0.711 ± 0.027	1.399IleTyr: 1.399 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	3.94LysAla: 3.94 ± 0.076	0.338LysCys: 0.338 ± 0.019	1.654LysAsp: 1.654 ± 0.043	1.988LysGlu: 1.988 ± 0.049	1.582LysPhe: 1.582 ± 0.042	2.506LysGly: 2.506 ± 0.052	0.635LysHis: 0.635 ± 0.025	3.1LysIle: 3.1 ± 0.058	2.176LysLys: 2.176 ± 0.051	4.0LysLeu: 4.0 ± 0.07	1.515LysMet: 1.515 ± 0.041	2.512LysAsn: 2.512 ± 0.057	2.401LysPro: 2.401 ± 0.058	1.324LysGln: 1.324 ± 0.04	2.86LysArg: 2.86 ± 0.051	3.164LysSer: 3.164 ± 0.055	3.004LysThr: 3.004 ± 0.047	2.729LysVal: 2.729 ± 0.054	0.759LysTrp: 0.759 ± 0.027	0.899LysTyr: 0.899 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	10.494LeuAla: 10.494 ± 0.112	1.283LeuCys: 1.283 ± 0.041	5.487LeuAsp: 5.487 ± 0.075	6.749LeuGlu: 6.749 ± 0.085	4.073LeuPhe: 4.073 ± 0.08	8.289LeuGly: 8.289 ± 0.105	1.962LeuHis: 1.962 ± 0.044	4.777LeuIle: 4.777 ± 0.081	4.406LeuLys: 4.406 ± 0.062	10.319LeuLeu: 10.319 ± 0.157	2.022LeuMet: 2.022 ± 0.054	3.184LeuAsn: 3.184 ± 0.057	5.663LeuPro: 5.663 ± 0.078	4.474LeuGln: 4.474 ± 0.078	6.951LeuArg: 6.951 ± 0.099	7.619LeuSer: 7.619 ± 0.095	4.728LeuThr: 4.728 ± 0.074	6.335LeuVal: 6.335 ± 0.087	1.592LeuTrp: 1.592 ± 0.045	1.934LeuTyr: 1.934 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.192MetAla: 2.192 ± 0.044	0.159MetCys: 0.159 ± 0.013	0.75MetAsp: 0.75 ± 0.027	1.098MetGlu: 1.098 ± 0.034	0.592MetPhe: 0.592 ± 0.022	1.422MetGly: 1.422 ± 0.045	0.358MetHis: 0.358 ± 0.019	1.019MetIle: 1.019 ± 0.032	1.471MetLys: 1.471 ± 0.041	1.926MetLeu: 1.926 ± 0.05	0.552MetMet: 0.552 ± 0.027	1.007MetAsn: 1.007 ± 0.034	1.234MetPro: 1.234 ± 0.037	0.88MetGln: 0.88 ± 0.029	1.491MetArg: 1.491 ± 0.041	1.433MetSer: 1.433 ± 0.041	1.195MetThr: 1.195 ± 0.032	1.132MetVal: 1.132 ± 0.039	0.272MetTrp: 0.272 ± 0.015	0.199MetTyr: 0.199 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.995AsnAla: 3.995 ± 0.066	0.342AsnCys: 0.342 ± 0.019	1.645AsnAsp: 1.645 ± 0.044	2.028AsnGlu: 2.028 ± 0.043	1.659AsnPhe: 1.659 ± 0.043	3.562AsnGly: 3.562 ± 0.076	0.692AsnHis: 0.692 ± 0.03	1.612AsnIle: 1.612 ± 0.038	1.038AsnLys: 1.038 ± 0.035	3.813AsnLeu: 3.813 ± 0.059	0.6AsnMet: 0.6 ± 0.026	1.14AsnAsn: 1.14 ± 0.042	2.353AsnPro: 2.353 ± 0.048	1.475AsnGln: 1.475 ± 0.039	2.392AsnArg: 2.392 ± 0.05	2.444AsnSer: 2.444 ± 0.053	1.646AsnThr: 1.646 ± 0.041	2.164AsnVal: 2.164 ± 0.046	0.651AsnTrp: 0.651 ± 0.024	1.011AsnTyr: 1.011 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	5.177ProAla: 5.177 ± 0.086	0.341ProCys: 0.341 ± 0.02	3.137ProAsp: 3.137 ± 0.049	3.264ProGlu: 3.264 ± 0.059	2.265ProPhe: 2.265 ± 0.047	3.688ProGly: 3.688 ± 0.069	1.02ProHis: 1.02 ± 0.028	2.703ProIle: 2.703 ± 0.057	2.004ProLys: 2.004 ± 0.049	5.459ProLeu: 5.459 ± 0.078	0.977ProMet: 0.977 ± 0.032	2.009ProAsn: 2.009 ± 0.049	2.302ProPro: 2.302 ± 0.061	2.562ProGln: 2.562 ± 0.053	3.277ProArg: 3.277 ± 0.061	3.111ProSer: 3.111 ± 0.062	2.823ProThr: 2.823 ± 0.059	3.546ProVal: 3.546 ± 0.067	0.589ProTrp: 0.589 ± 0.023	1.103ProTyr: 1.103 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.326GlnAla: 3.326 ± 0.075	0.242GlnCys: 0.242 ± 0.016	1.331GlnAsp: 1.331 ± 0.031	1.811GlnGlu: 1.811 ± 0.043	1.633GlnPhe: 1.633 ± 0.039	2.449GlnGly: 2.449 ± 0.05	0.643GlnHis: 0.643 ± 0.027	3.094GlnIle: 3.094 ± 0.056	2.679GlnLys: 2.679 ± 0.05	3.773GlnLeu: 3.773 ± 0.07	1.007GlnMet: 1.007 ± 0.03	2.377GlnAsn: 2.377 ± 0.052	1.669GlnPro: 1.669 ± 0.041	1.353GlnGln: 1.353 ± 0.043	2.358GlnArg: 2.358 ± 0.047	3.191GlnSer: 3.191 ± 0.067	2.663GlnThr: 2.663 ± 0.051	2.44GlnVal: 2.44 ± 0.05	0.582GlnTrp: 0.582 ± 0.024	0.685GlnTyr: 0.685 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	8.168ArgAla: 8.168 ± 0.128	0.449ArgCys: 0.449 ± 0.02	3.881ArgAsp: 3.881 ± 0.066	4.813ArgGlu: 4.813 ± 0.078	3.196ArgPhe: 3.196 ± 0.064	4.969ArgGly: 4.969 ± 0.078	1.213ArgHis: 1.213 ± 0.037	3.14ArgIle: 3.14 ± 0.053	2.171ArgLys: 2.171 ± 0.048	6.321ArgLeu: 6.321 ± 0.094	1.155ArgMet: 1.155 ± 0.034	1.99ArgAsn: 1.99 ± 0.044	2.741ArgPro: 2.741 ± 0.06	2.405ArgGln: 2.405 ± 0.051	4.594ArgArg: 4.594 ± 0.087	3.179ArgSer: 3.179 ± 0.066	2.631ArgThr: 2.631 ± 0.049	4.741ArgVal: 4.741 ± 0.077	0.869ArgTrp: 0.869 ± 0.032	1.486ArgTyr: 1.486 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	7.143SerAla: 7.143 ± 0.103	0.534SerCys: 0.534 ± 0.022	3.416SerAsp: 3.416 ± 0.061	3.655SerGlu: 3.655 ± 0.057	2.65SerPhe: 2.65 ± 0.051	6.268SerGly: 6.268 ± 0.1	1.324SerHis: 1.324 ± 0.039	2.963SerIle: 2.963 ± 0.052	2.407SerLys: 2.407 ± 0.054	6.334SerLeu: 6.334 ± 0.08	1.269SerMet: 1.269 ± 0.037	2.407SerAsn: 2.407 ± 0.054	3.664SerPro: 3.664 ± 0.06	2.762SerGln: 2.762 ± 0.055	3.927SerArg: 3.927 ± 0.067	4.253SerSer: 4.253 ± 0.065	3.253SerThr: 3.253 ± 0.06	4.181SerVal: 4.181 ± 0.061	0.879SerTrp: 0.879 ± 0.03	1.427SerTyr: 1.427 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	5.008ThrAla: 5.008 ± 0.066	0.417ThrCys: 0.417 ± 0.022	2.263ThrAsp: 2.263 ± 0.05	2.475ThrGlu: 2.475 ± 0.05	2.277ThrPhe: 2.277 ± 0.051	4.191ThrGly: 4.191 ± 0.069	1.001ThrHis: 1.001 ± 0.031	2.536ThrIle: 2.536 ± 0.052	2.192ThrLys: 2.192 ± 0.047	6.28ThrLeu: 6.28 ± 0.082	0.906ThrMet: 0.906 ± 0.035	1.54ThrAsn: 1.54 ± 0.044	3.779ThrPro: 3.779 ± 0.067	2.161ThrGln: 2.161 ± 0.05	3.383ThrArg: 3.383 ± 0.048	3.384ThrSer: 3.384 ± 0.062	2.919ThrThr: 2.919 ± 0.068	3.466ThrVal: 3.466 ± 0.061	0.695ThrTrp: 0.695 ± 0.029	1.234ThrTyr: 1.234 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	7.854ValAla: 7.854 ± 0.093	0.7ValCys: 0.7 ± 0.028	3.043ValAsp: 3.043 ± 0.056	4.362ValGlu: 4.362 ± 0.078	2.756ValPhe: 2.756 ± 0.057	4.812ValGly: 4.812 ± 0.074	1.136ValHis: 1.136 ± 0.031	3.171ValIle: 3.171 ± 0.051	2.647ValLys: 2.647 ± 0.055	6.756ValLeu: 6.756 ± 0.089	1.432ValMet: 1.432 ± 0.036	1.94ValAsn: 1.94 ± 0.044	3.619ValPro: 3.619 ± 0.06	2.251ValGln: 2.251 ± 0.043	4.226ValArg: 4.226 ± 0.064	4.763ValSer: 4.763 ± 0.066	3.59ValThr: 3.59 ± 0.06	5.033ValVal: 5.033 ± 0.079	0.955ValTrp: 0.955 ± 0.031	1.305ValTyr: 1.305 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.2TrpAla: 1.2 ± 0.034	0.166TrpCys: 0.166 ± 0.013	0.594TrpAsp: 0.594 ± 0.023	0.69TrpGlu: 0.69 ± 0.025	0.615TrpPhe: 0.615 ± 0.027	0.983TrpGly: 0.983 ± 0.033	0.356TrpHis: 0.356 ± 0.017	0.722TrpIle: 0.722 ± 0.029	0.897TrpLys: 0.897 ± 0.037	1.49TrpLeu: 1.49 ± 0.043	0.463TrpMet: 0.463 ± 0.022	0.925TrpAsn: 0.925 ± 0.029	0.694TrpPro: 0.694 ± 0.027	0.693TrpGln: 0.693 ± 0.024	1.103TrpArg: 1.103 ± 0.037	0.971TrpSer: 0.971 ± 0.033	0.762TrpThr: 0.762 ± 0.028	0.769TrpVal: 0.769 ± 0.027	0.237TrpTrp: 0.237 ± 0.016	0.253TrpTyr: 0.253 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.283TyrAla: 2.283 ± 0.044	0.214TyrCys: 0.214 ± 0.014	1.268TyrAsp: 1.268 ± 0.035	1.216TyrGlu: 1.216 ± 0.034	1.148TyrPhe: 1.148 ± 0.033	1.935TyrGly: 1.935 ± 0.043	0.443TyrHis: 0.443 ± 0.022	0.973TyrIle: 0.973 ± 0.032	0.751TyrLys: 0.751 ± 0.029	2.39TyrLeu: 2.39 ± 0.055	0.274TyrMet: 0.274 ± 0.015	0.797TyrAsn: 0.797 ± 0.031	1.048TyrPro: 1.048 ± 0.039	0.905TyrGln: 0.905 ± 0.027	1.536TyrArg: 1.536 ± 0.045	1.373TyrSer: 1.373 ± 0.036	1.036TyrThr: 1.036 ± 0.032	1.34TyrVal: 1.34 ± 0.034	0.313TyrTrp: 0.313 ± 0.019	0.59TyrTyr: 0.59 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3182 proteins (1065418 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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