Amino acid dipepetide frequency for Bacteroidetes oral taxon 274 str. F0058

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.339AlaAla: 5.339 ± 0.136
0.773AlaCys: 0.773 ± 0.034
4.772AlaAsp: 4.772 ± 0.11
4.663AlaGlu: 4.663 ± 0.102
3.108AlaPhe: 3.108 ± 0.082
4.694AlaGly: 4.694 ± 0.112
1.081AlaHis: 1.081 ± 0.045
5.524AlaIle: 5.524 ± 0.118
4.872AlaLys: 4.872 ± 0.111
5.991AlaLeu: 5.991 ± 0.122
1.845AlaMet: 1.845 ± 0.056
3.282AlaAsn: 3.282 ± 0.072
1.816AlaPro: 1.816 ± 0.06
2.424AlaGln: 2.424 ± 0.062
2.924AlaArg: 2.924 ± 0.09
3.911AlaSer: 3.911 ± 0.086
4.158AlaThr: 4.158 ± 0.093
4.918AlaVal: 4.918 ± 0.115
0.495AlaTrp: 0.495 ± 0.032
2.577AlaTyr: 2.577 ± 0.069
0.0AlaXaa: 0.0 ± 0.0
Cys
0.631CysAla: 0.631 ± 0.032
0.2CysCys: 0.2 ± 0.02
0.598CysAsp: 0.598 ± 0.037
0.629CysGlu: 0.629 ± 0.03
0.603CysPhe: 0.603 ± 0.035
1.083CysGly: 1.083 ± 0.043
0.25CysHis: 0.25 ± 0.021
0.821CysIle: 0.821 ± 0.043
0.75CysLys: 0.75 ± 0.042
0.941CysLeu: 0.941 ± 0.041
0.257CysMet: 0.257 ± 0.019
0.626CysAsn: 0.626 ± 0.033
0.518CysPro: 0.518 ± 0.048
0.321CysGln: 0.321 ± 0.023
0.785CysArg: 0.785 ± 0.027
0.891CysSer: 0.891 ± 0.047
0.586CysThr: 0.586 ± 0.032
0.71CysVal: 0.71 ± 0.035
0.111CysTrp: 0.111 ± 0.011
0.523CysTyr: 0.523 ± 0.037
0.0CysXaa: 0.0 ± 0.0
Asp
3.294AspAla: 3.294 ± 0.073
0.743AspCys: 0.743 ± 0.04
3.128AspAsp: 3.128 ± 0.078
3.944AspGlu: 3.944 ± 0.085
3.348AspPhe: 3.348 ± 0.072
3.862AspGly: 3.862 ± 0.094
0.578AspHis: 0.578 ± 0.037
5.499AspIle: 5.499 ± 0.111
4.978AspLys: 4.978 ± 0.099
4.3AspLeu: 4.3 ± 0.094
1.623AspMet: 1.623 ± 0.059
3.913AspAsn: 3.913 ± 0.081
1.374AspPro: 1.374 ± 0.052
0.863AspGln: 0.863 ± 0.039
2.651AspArg: 2.651 ± 0.067
3.54AspSer: 3.54 ± 0.075
3.385AspThr: 3.385 ± 0.075
3.691AspVal: 3.691 ± 0.09
0.609AspTrp: 0.609 ± 0.031
2.913AspTyr: 2.913 ± 0.07
0.0AspXaa: 0.0 ± 0.0
Glu
4.61GluAla: 4.61 ± 0.099
0.571GluCys: 0.571 ± 0.032
2.871GluAsp: 2.871 ± 0.075
4.05GluGlu: 4.05 ± 0.103
2.679GluPhe: 2.679 ± 0.077
3.426GluGly: 3.426 ± 0.084
1.197GluHis: 1.197 ± 0.049
4.983GluIle: 4.983 ± 0.092
4.986GluLys: 4.986 ± 0.105
5.767GluLeu: 5.767 ± 0.128
1.618GluMet: 1.618 ± 0.053
3.572GluAsn: 3.572 ± 0.072
1.54GluPro: 1.54 ± 0.058
2.681GluGln: 2.681 ± 0.078
3.237GluArg: 3.237 ± 0.072
2.664GluSer: 2.664 ± 0.062
2.949GluThr: 2.949 ± 0.076
4.024GluVal: 4.024 ± 0.079
0.652GluTrp: 0.652 ± 0.035
2.714GluTyr: 2.714 ± 0.075
0.0GluXaa: 0.0 ± 0.0
Phe
3.712PheAla: 3.712 ± 0.092
0.74PheCys: 0.74 ± 0.035
3.502PheAsp: 3.502 ± 0.07
2.865PheGlu: 2.865 ± 0.074
2.499PhePhe: 2.499 ± 0.074
3.59PheGly: 3.59 ± 0.084
0.644PheHis: 0.644 ± 0.033
3.206PheIle: 3.206 ± 0.082
2.429PheLys: 2.429 ± 0.063
3.833PheLeu: 3.833 ± 0.079
1.209PheMet: 1.209 ± 0.048
2.158PheAsn: 2.158 ± 0.072
1.561PhePro: 1.561 ± 0.051
0.937PheGln: 0.937 ± 0.041
2.25PheArg: 2.25 ± 0.067
3.431PheSer: 3.431 ± 0.082
2.63PheThr: 2.63 ± 0.057
3.967PheVal: 3.967 ± 0.102
0.525PheTrp: 0.525 ± 0.032
2.004PheTyr: 2.004 ± 0.063
0.0PheXaa: 0.0 ± 0.0
Gly
4.242GlyAla: 4.242 ± 0.101
0.883GlyCys: 0.883 ± 0.052
3.351GlyAsp: 3.351 ± 0.079
3.648GlyGlu: 3.648 ± 0.076
3.247GlyPhe: 3.247 ± 0.085
4.524GlyGly: 4.524 ± 0.11
1.063GlyHis: 1.063 ± 0.046
5.6GlyIle: 5.6 ± 0.106
5.43GlyLys: 5.43 ± 0.112
5.249GlyLeu: 5.249 ± 0.102
1.585GlyMet: 1.585 ± 0.056
3.721GlyAsn: 3.721 ± 0.08
0.753GlyPro: 0.753 ± 0.038
1.994GlyGln: 1.994 ± 0.06
2.841GlyArg: 2.841 ± 0.081
4.092GlySer: 4.092 ± 0.093
3.588GlyThr: 3.588 ± 0.094
4.617GlyVal: 4.617 ± 0.098
0.676GlyTrp: 0.676 ± 0.029
3.169GlyTyr: 3.169 ± 0.075
0.0GlyXaa: 0.0 ± 0.0
His
0.777HisAla: 0.777 ± 0.039
0.285HisCys: 0.285 ± 0.022
0.747HisAsp: 0.747 ± 0.038
0.747HisGlu: 0.747 ± 0.036
0.922HisPhe: 0.922 ± 0.038
1.03HisGly: 1.03 ± 0.047
0.371HisHis: 0.371 ± 0.027
1.618HisIle: 1.618 ± 0.059
1.247HisLys: 1.247 ± 0.045
1.576HisLeu: 1.576 ± 0.048
0.179HisMet: 0.179 ± 0.016
1.136HisAsn: 1.136 ± 0.05
0.753HisPro: 0.753 ± 0.038
0.48HisGln: 0.48 ± 0.028
0.952HisArg: 0.952 ± 0.044
1.224HisSer: 1.224 ± 0.045
1.152HisThr: 1.152 ± 0.04
0.654HisVal: 0.654 ± 0.033
0.184HisTrp: 0.184 ± 0.017
0.889HisTyr: 0.889 ± 0.039
0.0HisXaa: 0.0 ± 0.0
Ile
6.291IleAla: 6.291 ± 0.111
0.929IleCys: 0.929 ± 0.037
5.678IleAsp: 5.678 ± 0.112
5.408IleGlu: 5.408 ± 0.11
3.602IlePhe: 3.602 ± 0.087
5.143IleGly: 5.143 ± 0.099
1.174IleHis: 1.174 ± 0.045
5.696IleIle: 5.696 ± 0.104
5.373IleLys: 5.373 ± 0.099
6.509IleLeu: 6.509 ± 0.12
1.57IleMet: 1.57 ± 0.042
4.163IleAsn: 4.163 ± 0.086
3.068IlePro: 3.068 ± 0.072
1.932IleGln: 1.932 ± 0.052
3.527IleArg: 3.527 ± 0.076
5.633IleSer: 5.633 ± 0.11
4.66IleThr: 4.66 ± 0.094
5.91IleVal: 5.91 ± 0.112
0.583IleTrp: 0.583 ± 0.037
3.164IleTyr: 3.164 ± 0.08
0.0IleXaa: 0.0 ± 0.0
Lys
4.736LysAla: 4.736 ± 0.101
0.55LysCys: 0.55 ± 0.036
3.974LysAsp: 3.974 ± 0.089
5.093LysGlu: 5.093 ± 0.117
2.601LysPhe: 2.601 ± 0.067
4.29LysGly: 4.29 ± 0.098
1.277LysHis: 1.277 ± 0.048
6.302LysIle: 6.302 ± 0.126
5.623LysLys: 5.623 ± 0.117
5.713LysLeu: 5.713 ± 0.106
2.283LysMet: 2.283 ± 0.061
4.933LysAsn: 4.933 ± 0.099
2.368LysPro: 2.368 ± 0.072
2.553LysGln: 2.553 ± 0.076
3.216LysArg: 3.216 ± 0.079
4.078LysSer: 4.078 ± 0.083
4.411LysThr: 4.411 ± 0.099
4.166LysVal: 4.166 ± 0.105
0.613LysTrp: 0.613 ± 0.033
3.181LysTyr: 3.181 ± 0.08
0.0LysXaa: 0.0 ± 0.0
Leu
5.96LeuAla: 5.96 ± 0.123
1.114LeuCys: 1.114 ± 0.043
4.958LeuAsp: 4.958 ± 0.113
4.574LeuGlu: 4.574 ± 0.092
4.216LeuPhe: 4.216 ± 0.106
5.463LeuGly: 5.463 ± 0.112
1.56LeuHis: 1.56 ± 0.053
6.168LeuIle: 6.168 ± 0.128
5.868LeuLys: 5.868 ± 0.119
8.306LeuLeu: 8.306 ± 0.165
2.09LeuMet: 2.09 ± 0.059
4.54LeuAsn: 4.54 ± 0.097
3.913LeuPro: 3.913 ± 0.084
2.941LeuGln: 2.941 ± 0.08
4.352LeuArg: 4.352 ± 0.094
6.67LeuSer: 6.67 ± 0.126
5.112LeuThr: 5.112 ± 0.111
5.044LeuVal: 5.044 ± 0.095
0.864LeuTrp: 0.864 ± 0.036
3.56LeuTyr: 3.56 ± 0.071
0.0LeuXaa: 0.0 ± 0.0
Met
1.901MetAla: 1.901 ± 0.053
0.233MetCys: 0.233 ± 0.018
1.048MetAsp: 1.048 ± 0.045
1.376MetGlu: 1.376 ± 0.057
1.237MetPhe: 1.237 ± 0.052
1.55MetGly: 1.55 ± 0.057
0.406MetHis: 0.406 ± 0.031
1.719MetIle: 1.719 ± 0.049
2.012MetLys: 2.012 ± 0.058
2.355MetLeu: 2.355 ± 0.065
0.669MetMet: 0.669 ± 0.036
1.368MetAsn: 1.368 ± 0.043
1.162MetPro: 1.162 ± 0.049
0.975MetGln: 0.975 ± 0.041
1.207MetArg: 1.207 ± 0.045
1.623MetSer: 1.623 ± 0.051
1.359MetThr: 1.359 ± 0.049
1.373MetVal: 1.373 ± 0.042
0.185MetTrp: 0.185 ± 0.017
0.891MetTyr: 0.891 ± 0.035
0.0MetXaa: 0.0 ± 0.0
Asn
3.651AsnAla: 3.651 ± 0.089
0.614AsnCys: 0.614 ± 0.038
2.81AsnAsp: 2.81 ± 0.077
2.807AsnGlu: 2.807 ± 0.068
2.514AsnPhe: 2.514 ± 0.076
3.628AsnGly: 3.628 ± 0.092
0.825AsnHis: 0.825 ± 0.039
5.435AsnIle: 5.435 ± 0.105
4.146AsnLys: 4.146 ± 0.107
4.428AsnLeu: 4.428 ± 0.097
1.482AsnMet: 1.482 ± 0.062
3.307AsnAsn: 3.307 ± 0.084
2.487AsnPro: 2.487 ± 0.07
1.431AsnGln: 1.431 ± 0.051
2.542AsnArg: 2.542 ± 0.069
3.404AsnSer: 3.404 ± 0.083
3.381AsnThr: 3.381 ± 0.089
3.292AsnVal: 3.292 ± 0.086
0.55AsnTrp: 0.55 ± 0.029
2.399AsnTyr: 2.399 ± 0.067
0.0AsnXaa: 0.0 ± 0.0
Pro
2.227ProAla: 2.227 ± 0.063
0.338ProCys: 0.338 ± 0.026
2.355ProAsp: 2.355 ± 0.065
2.338ProGlu: 2.338 ± 0.063
1.702ProPhe: 1.702 ± 0.056
1.262ProGly: 1.262 ± 0.048
0.768ProHis: 0.768 ± 0.041
2.59ProIle: 2.59 ± 0.055
2.373ProLys: 2.373 ± 0.063
2.858ProLeu: 2.858 ± 0.078
0.806ProMet: 0.806 ± 0.041
1.879ProAsn: 1.879 ± 0.057
0.929ProPro: 0.929 ± 0.04
1.578ProGln: 1.578 ± 0.051
1.191ProArg: 1.191 ± 0.047
2.093ProSer: 2.093 ± 0.06
2.023ProThr: 2.023 ± 0.06
2.394ProVal: 2.394 ± 0.06
0.217ProTrp: 0.217 ± 0.018
1.621ProTyr: 1.621 ± 0.055
0.0ProXaa: 0.0 ± 0.0
Gln
2.156GlnAla: 2.156 ± 0.058
0.291GlnCys: 0.291 ± 0.026
1.321GlnAsp: 1.321 ± 0.044
1.823GlnGlu: 1.823 ± 0.063
1.239GlnPhe: 1.239 ± 0.042
1.755GlnGly: 1.755 ± 0.064
0.566GlnHis: 0.566 ± 0.032
2.658GlnIle: 2.658 ± 0.076
2.762GlnLys: 2.762 ± 0.076
2.817GlnLeu: 2.817 ± 0.077
0.949GlnMet: 0.949 ± 0.04
1.909GlnAsn: 1.909 ± 0.059
1.053GlnPro: 1.053 ± 0.037
1.401GlnGln: 1.401 ± 0.062
1.661GlnArg: 1.661 ± 0.055
1.865GlnSer: 1.865 ± 0.051
2.191GlnThr: 2.191 ± 0.057
1.712GlnVal: 1.712 ± 0.052
0.386GlnTrp: 0.386 ± 0.029
1.48GlnTyr: 1.48 ± 0.05
0.0GlnXaa: 0.0 ± 0.0
Arg
2.631ArgAla: 2.631 ± 0.066
0.475ArgCys: 0.475 ± 0.024
2.265ArgAsp: 2.265 ± 0.057
2.702ArgGlu: 2.702 ± 0.076
2.409ArgPhe: 2.409 ± 0.071
2.563ArgGly: 2.563 ± 0.064
1.096ArgHis: 1.096 ± 0.048
3.857ArgIle: 3.857 ± 0.091
3.385ArgLys: 3.385 ± 0.072
4.668ArgLeu: 4.668 ± 0.091
1.215ArgMet: 1.215 ± 0.051
2.673ArgAsn: 2.673 ± 0.065
1.422ArgPro: 1.422 ± 0.061
2.239ArgGln: 2.239 ± 0.072
2.878ArgArg: 2.878 ± 0.089
2.388ArgSer: 2.388 ± 0.075
2.232ArgThr: 2.232 ± 0.061
2.676ArgVal: 2.676 ± 0.07
0.543ArgTrp: 0.543 ± 0.028
2.485ArgTyr: 2.485 ± 0.07
0.0ArgXaa: 0.0 ± 0.0
Ser
4.319SerAla: 4.319 ± 0.085
0.775SerCys: 0.775 ± 0.04
3.721SerAsp: 3.721 ± 0.076
3.592SerGlu: 3.592 ± 0.084
3.077SerPhe: 3.077 ± 0.086
4.421SerGly: 4.421 ± 0.101
1.161SerHis: 1.161 ± 0.047
5.062SerIle: 5.062 ± 0.112
4.179SerLys: 4.179 ± 0.086
6.254SerLeu: 6.254 ± 0.123
1.363SerMet: 1.363 ± 0.049
3.113SerAsn: 3.113 ± 0.082
2.278SerPro: 2.278 ± 0.061
2.005SerGln: 2.005 ± 0.052
2.711SerArg: 2.711 ± 0.076
4.024SerSer: 4.024 ± 0.106
3.284SerThr: 3.284 ± 0.086
4.729SerVal: 4.729 ± 0.086
0.621SerTrp: 0.621 ± 0.036
2.661SerTyr: 2.661 ± 0.074
0.0SerXaa: 0.0 ± 0.0
Thr
4.256ThrAla: 4.256 ± 0.088
0.435ThrCys: 0.435 ± 0.026
4.002ThrAsp: 4.002 ± 0.089
3.448ThrGlu: 3.448 ± 0.076
2.553ThrPhe: 2.553 ± 0.072
3.694ThrGly: 3.694 ± 0.089
0.98ThrHis: 0.98 ± 0.036
4.539ThrIle: 4.539 ± 0.088
3.547ThrLys: 3.547 ± 0.074
5.178ThrLeu: 5.178 ± 0.104
1.174ThrMet: 1.174 ± 0.042
2.659ThrAsn: 2.659 ± 0.078
2.5ThrPro: 2.5 ± 0.059
1.777ThrGln: 1.777 ± 0.055
1.989ThrArg: 1.989 ± 0.065
3.457ThrSer: 3.457 ± 0.085
3.356ThrThr: 3.356 ± 0.085
4.459ThrVal: 4.459 ± 0.091
0.462ThrTrp: 0.462 ± 0.027
2.103ThrTyr: 2.103 ± 0.063
0.0ThrXaa: 0.0 ± 0.0
Val
5.166ValAla: 5.166 ± 0.124
1.033ValCys: 1.033 ± 0.044
3.943ValAsp: 3.943 ± 0.095
4.176ValGlu: 4.176 ± 0.078
3.451ValPhe: 3.451 ± 0.091
4.554ValGly: 4.554 ± 0.085
0.904ValHis: 0.904 ± 0.04
4.746ValIle: 4.746 ± 0.106
4.285ValLys: 4.285 ± 0.097
5.723ValLeu: 5.723 ± 0.096
1.61ValMet: 1.61 ± 0.054
3.06ValAsn: 3.06 ± 0.072
2.283ValPro: 2.283 ± 0.063
1.672ValGln: 1.672 ± 0.047
3.009ValArg: 3.009 ± 0.076
4.817ValSer: 4.817 ± 0.099
3.222ValThr: 3.222 ± 0.09
5.175ValVal: 5.175 ± 0.107
0.818ValTrp: 0.818 ± 0.049
2.828ValTyr: 2.828 ± 0.08
0.0ValXaa: 0.0 ± 0.0
Trp
0.676TrpAla: 0.676 ± 0.033
0.113TrpCys: 0.113 ± 0.012
0.525TrpAsp: 0.525 ± 0.031
0.533TrpGlu: 0.533 ± 0.035
0.474TrpPhe: 0.474 ± 0.03
0.743TrpGly: 0.743 ± 0.039
0.285TrpHis: 0.285 ± 0.022
0.669TrpIle: 0.669 ± 0.036
0.734TrpLys: 0.734 ± 0.048
1.056TrpLeu: 1.056 ± 0.042
0.202TrpMet: 0.202 ± 0.017
0.492TrpAsn: 0.492 ± 0.033
0.073TrpPro: 0.073 ± 0.012
0.548TrpGln: 0.548 ± 0.032
0.472TrpArg: 0.472 ± 0.032
0.475TrpSer: 0.475 ± 0.028
0.498TrpThr: 0.498 ± 0.036
0.581TrpVal: 0.581 ± 0.036
0.131TrpTrp: 0.131 ± 0.016
0.394TrpTyr: 0.394 ± 0.027
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.595TyrAla: 2.595 ± 0.06
0.737TyrCys: 0.737 ± 0.048
2.666TyrAsp: 2.666 ± 0.064
2.378TyrGlu: 2.378 ± 0.066
2.212TyrPhe: 2.212 ± 0.065
2.997TyrGly: 2.997 ± 0.077
0.737TyrHis: 0.737 ± 0.037
3.323TyrIle: 3.323 ± 0.076
2.984TyrLys: 2.984 ± 0.064
3.749TyrLeu: 3.749 ± 0.075
0.921TyrMet: 0.921 ± 0.041
2.63TyrAsn: 2.63 ± 0.07
1.687TyrPro: 1.687 ± 0.051
1.242TyrGln: 1.242 ± 0.044
2.409TyrArg: 2.409 ± 0.072
3.068TyrSer: 3.068 ± 0.084
2.391TyrThr: 2.391 ± 0.072
2.383TyrVal: 2.383 ± 0.061
0.449TyrTrp: 0.449 ± 0.032
2.085TyrTyr: 2.085 ± 0.067
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1854 proteins (603910 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski