Amino acid dipepetide frequency for Sorghum chlorotic spot virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.689AlaAla: 6.689 ± 1.109
0.669AlaCys: 0.669 ± 0.431
4.682AlaAsp: 4.682 ± 1.395
3.679AlaGlu: 3.679 ± 1.444
3.679AlaPhe: 3.679 ± 1.2
2.676AlaGly: 2.676 ± 1.121
1.003AlaHis: 1.003 ± 0.532
3.344AlaIle: 3.344 ± 0.862
2.007AlaLys: 2.007 ± 0.485
8.696AlaLeu: 8.696 ± 2.974
3.344AlaMet: 3.344 ± 1.56
3.344AlaAsn: 3.344 ± 0.667
1.003AlaPro: 1.003 ± 0.511
3.01AlaGln: 3.01 ± 0.896
4.682AlaArg: 4.682 ± 1.322
4.682AlaSer: 4.682 ± 1.9
3.679AlaThr: 3.679 ± 0.837
6.02AlaVal: 6.02 ± 1.422
0.0AlaTrp: 0.0 ± 0.142
2.676AlaTyr: 2.676 ± 0.56
0.0AlaXaa: 0.0 ± 0.0
Cys
1.338CysAla: 1.338 ± 0.906
0.669CysCys: 0.669 ± 0.404
3.01CysAsp: 3.01 ± 0.504
2.341CysGlu: 2.341 ± 0.84
1.003CysPhe: 1.003 ± 0.461
2.341CysGly: 2.341 ± 0.929
0.0CysHis: 0.0 ± 0.0
0.669CysIle: 0.669 ± 0.404
1.338CysLys: 1.338 ± 0.749
0.334CysLeu: 0.334 ± 0.467
0.0CysMet: 0.0 ± 0.0
0.334CysAsn: 0.334 ± 0.202
0.334CysPro: 0.334 ± 0.202
1.003CysGln: 1.003 ± 0.402
0.669CysArg: 0.669 ± 0.311
0.669CysSer: 0.669 ± 0.311
1.003CysThr: 1.003 ± 0.37
1.672CysVal: 1.672 ± 0.843
0.0CysTrp: 0.0 ± 0.0
0.334CysTyr: 0.334 ± 0.202
0.0CysXaa: 0.0 ± 0.0
Asp
3.01AspAla: 3.01 ± 0.578
1.672AspCys: 1.672 ± 0.226
3.01AspAsp: 3.01 ± 0.865
3.679AspGlu: 3.679 ± 0.585
4.013AspPhe: 4.013 ± 0.895
5.351AspGly: 5.351 ± 0.834
1.003AspHis: 1.003 ± 0.348
3.679AspIle: 3.679 ± 0.884
4.348AspLys: 4.348 ± 0.986
8.361AspLeu: 8.361 ± 1.627
0.669AspMet: 0.669 ± 0.404
2.676AspAsn: 2.676 ± 1.086
2.007AspPro: 2.007 ± 0.639
3.344AspGln: 3.344 ± 0.769
5.017AspArg: 5.017 ± 1.454
4.348AspSer: 4.348 ± 0.6
4.013AspThr: 4.013 ± 1.959
5.017AspVal: 5.017 ± 1.664
0.334AspTrp: 0.334 ± 0.477
1.003AspTyr: 1.003 ± 0.308
0.0AspXaa: 0.0 ± 0.0
Glu
7.023GluAla: 7.023 ± 1.31
0.669GluCys: 0.669 ± 0.311
6.689GluAsp: 6.689 ± 1.104
5.686GluGlu: 5.686 ± 0.8
3.01GluPhe: 3.01 ± 1.018
4.013GluGly: 4.013 ± 1.228
0.669GluHis: 0.669 ± 0.404
4.013GluIle: 4.013 ± 0.895
7.692GluLys: 7.692 ± 2.437
6.355GluLeu: 6.355 ± 1.192
2.341GluMet: 2.341 ± 0.678
2.341GluAsn: 2.341 ± 0.7
0.669GluPro: 0.669 ± 0.276
2.676GluGln: 2.676 ± 1.131
4.348GluArg: 4.348 ± 0.634
4.682GluSer: 4.682 ± 0.638
3.01GluThr: 3.01 ± 1.718
5.351GluVal: 5.351 ± 1.006
0.669GluTrp: 0.669 ± 0.434
1.338GluTyr: 1.338 ± 0.288
0.0GluXaa: 0.0 ± 0.0
Phe
3.679PheAla: 3.679 ± 1.102
1.003PheCys: 1.003 ± 0.434
3.01PheAsp: 3.01 ± 1.011
4.013PheGlu: 4.013 ± 0.485
2.341PhePhe: 2.341 ± 0.468
3.679PheGly: 3.679 ± 1.442
0.334PheHis: 0.334 ± 0.202
0.669PheIle: 0.669 ± 0.639
1.003PheLys: 1.003 ± 0.485
2.676PheLeu: 2.676 ± 0.936
1.672PheMet: 1.672 ± 0.909
3.01PheAsn: 3.01 ± 1.052
2.007PhePro: 2.007 ± 0.932
0.334PheGln: 0.334 ± 0.477
1.338PheArg: 1.338 ± 0.284
4.013PheSer: 4.013 ± 1.255
2.676PheThr: 2.676 ± 0.785
4.348PheVal: 4.348 ± 0.812
0.334PheTrp: 0.334 ± 0.202
1.003PheTyr: 1.003 ± 0.402
0.0PheXaa: 0.0 ± 0.0
Gly
1.672GlyAla: 1.672 ± 0.83
0.669GlyCys: 0.669 ± 0.404
4.682GlyAsp: 4.682 ± 1.19
4.348GlyGlu: 4.348 ± 0.87
2.676GlyPhe: 2.676 ± 0.715
5.017GlyGly: 5.017 ± 2.197
0.669GlyHis: 0.669 ± 0.404
2.007GlyIle: 2.007 ± 0.616
4.013GlyLys: 4.013 ± 1.317
4.013GlyLeu: 4.013 ± 1.304
1.672GlyMet: 1.672 ± 0.79
2.007GlyAsn: 2.007 ± 0.588
2.341GlyPro: 2.341 ± 0.677
0.669GlyGln: 0.669 ± 0.311
2.676GlyArg: 2.676 ± 0.595
3.679GlySer: 3.679 ± 0.509
5.351GlyThr: 5.351 ± 2.583
5.017GlyVal: 5.017 ± 1.48
0.0GlyTrp: 0.0 ± 0.0
2.676GlyTyr: 2.676 ± 0.878
0.0GlyXaa: 0.0 ± 0.0
His
1.672HisAla: 1.672 ± 0.7
0.669HisCys: 0.669 ± 0.423
1.672HisAsp: 1.672 ± 0.761
1.003HisGlu: 1.003 ± 0.348
0.334HisPhe: 0.334 ± 0.202
0.334HisGly: 0.334 ± 0.335
0.0HisHis: 0.0 ± 0.0
1.672HisIle: 1.672 ± 0.472
1.338HisLys: 1.338 ± 0.503
0.334HisLeu: 0.334 ± 0.335
0.334HisMet: 0.334 ± 0.335
1.338HisAsn: 1.338 ± 0.556
0.0HisPro: 0.0 ± 0.0
0.334HisGln: 0.334 ± 0.202
1.003HisArg: 1.003 ± 0.348
1.003HisSer: 1.003 ± 0.468
2.007HisThr: 2.007 ± 0.47
1.672HisVal: 1.672 ± 0.466
0.0HisTrp: 0.0 ± 0.0
0.334HisTyr: 0.334 ± 0.329
0.0HisXaa: 0.0 ± 0.0
Ile
3.01IleAla: 3.01 ± 0.941
1.003IleCys: 1.003 ± 0.348
3.01IleAsp: 3.01 ± 0.691
5.351IleGlu: 5.351 ± 0.952
1.672IlePhe: 1.672 ± 0.941
2.007IleGly: 2.007 ± 0.827
1.003IleHis: 1.003 ± 0.485
1.672IleIle: 1.672 ± 0.472
1.672IleLys: 1.672 ± 0.391
4.348IleLeu: 4.348 ± 0.835
0.669IleMet: 0.669 ± 0.408
2.007IleAsn: 2.007 ± 0.39
2.341IlePro: 2.341 ± 0.986
2.007IleGln: 2.007 ± 0.434
3.01IleArg: 3.01 ± 0.558
3.344IleSer: 3.344 ± 0.567
1.003IleThr: 1.003 ± 0.606
4.013IleVal: 4.013 ± 0.707
0.334IleTrp: 0.334 ± 0.202
1.003IleTyr: 1.003 ± 0.606
0.0IleXaa: 0.0 ± 0.0
Lys
3.679LysAla: 3.679 ± 1.145
0.669LysCys: 0.669 ± 0.404
5.351LysAsp: 5.351 ± 1.528
6.02LysGlu: 6.02 ± 2.185
3.344LysPhe: 3.344 ± 1.144
3.01LysGly: 3.01 ± 0.71
0.669LysHis: 0.669 ± 0.574
3.344LysIle: 3.344 ± 0.987
4.013LysLys: 4.013 ± 1.13
5.351LysLeu: 5.351 ± 1.087
2.007LysMet: 2.007 ± 0.767
2.341LysAsn: 2.341 ± 0.978
3.344LysPro: 3.344 ± 0.844
2.341LysGln: 2.341 ± 1.114
5.686LysArg: 5.686 ± 0.632
4.348LysSer: 4.348 ± 0.983
3.344LysThr: 3.344 ± 0.959
5.017LysVal: 5.017 ± 1.444
0.669LysTrp: 0.669 ± 0.772
2.341LysTyr: 2.341 ± 0.993
0.0LysXaa: 0.0 ± 0.0
Leu
6.02LeuAla: 6.02 ± 2.96
0.669LeuCys: 0.669 ± 0.434
5.017LeuAsp: 5.017 ± 1.014
5.351LeuGlu: 5.351 ± 0.983
6.02LeuPhe: 6.02 ± 1.368
4.682LeuGly: 4.682 ± 0.948
1.338LeuHis: 1.338 ± 0.556
3.01LeuIle: 3.01 ± 1.086
7.358LeuLys: 7.358 ± 2.546
6.355LeuLeu: 6.355 ± 0.966
3.344LeuMet: 3.344 ± 0.538
4.682LeuAsn: 4.682 ± 1.265
3.01LeuPro: 3.01 ± 1.016
4.682LeuGln: 4.682 ± 1.472
7.692LeuArg: 7.692 ± 2.343
5.351LeuSer: 5.351 ± 0.889
3.01LeuThr: 3.01 ± 0.557
4.682LeuVal: 4.682 ± 1.344
2.007LeuTrp: 2.007 ± 0.802
3.344LeuTyr: 3.344 ± 0.73
0.0LeuXaa: 0.0 ± 0.0
Met
3.344MetAla: 3.344 ± 1.375
0.0MetCys: 0.0 ± 0.0
0.669MetAsp: 0.669 ± 0.311
2.341MetGlu: 2.341 ± 0.798
1.003MetPhe: 1.003 ± 0.308
1.672MetGly: 1.672 ± 0.498
0.669MetHis: 0.669 ± 0.362
1.672MetIle: 1.672 ± 0.599
2.007MetLys: 2.007 ± 0.32
2.007MetLeu: 2.007 ± 0.994
1.672MetMet: 1.672 ± 0.52
1.003MetAsn: 1.003 ± 0.434
1.338MetPro: 1.338 ± 0.749
0.334MetGln: 0.334 ± 0.335
2.341MetArg: 2.341 ± 0.523
0.669MetSer: 0.669 ± 0.408
2.676MetThr: 2.676 ± 0.56
2.676MetVal: 2.676 ± 0.812
0.669MetTrp: 0.669 ± 0.38
1.003MetTyr: 1.003 ± 0.334
0.0MetXaa: 0.0 ± 0.0
Asn
4.348AsnAla: 4.348 ± 1.384
1.672AsnCys: 1.672 ± 0.69
3.01AsnAsp: 3.01 ± 0.892
3.01AsnGlu: 3.01 ± 1.096
2.007AsnPhe: 2.007 ± 0.434
2.676AsnGly: 2.676 ± 0.509
0.669AsnHis: 0.669 ± 0.542
1.003AsnIle: 1.003 ± 0.485
2.676AsnLys: 2.676 ± 1.016
3.01AsnLeu: 3.01 ± 1.127
2.341AsnMet: 2.341 ± 0.799
1.003AsnAsn: 1.003 ± 0.606
1.672AsnPro: 1.672 ± 0.865
0.669AsnGln: 0.669 ± 0.276
2.341AsnArg: 2.341 ± 0.904
4.013AsnSer: 4.013 ± 0.428
2.341AsnThr: 2.341 ± 0.468
3.344AsnVal: 3.344 ± 1.623
0.669AsnTrp: 0.669 ± 0.276
1.003AsnTyr: 1.003 ± 0.402
0.0AsnXaa: 0.0 ± 0.0
Pro
2.676ProAla: 2.676 ± 1.481
1.338ProCys: 1.338 ± 0.851
3.344ProAsp: 3.344 ± 0.869
2.341ProGlu: 2.341 ± 0.569
0.669ProPhe: 0.669 ± 0.276
1.672ProGly: 1.672 ± 0.478
1.338ProHis: 1.338 ± 0.667
1.003ProIle: 1.003 ± 0.485
3.344ProLys: 3.344 ± 0.567
2.676ProLeu: 2.676 ± 0.62
1.003ProMet: 1.003 ± 0.485
1.003ProAsn: 1.003 ± 0.485
1.338ProPro: 1.338 ± 0.438
1.672ProGln: 1.672 ± 0.226
2.007ProArg: 2.007 ± 0.617
1.338ProSer: 1.338 ± 0.498
1.003ProThr: 1.003 ± 0.485
1.338ProVal: 1.338 ± 0.621
0.0ProTrp: 0.0 ± 0.0
1.338ProTyr: 1.338 ± 0.373
0.0ProXaa: 0.0 ± 0.0
Gln
1.003GlnAla: 1.003 ± 0.878
0.669GlnCys: 0.669 ± 0.434
2.007GlnAsp: 2.007 ± 1.109
2.676GlnGlu: 2.676 ± 0.749
1.672GlnPhe: 1.672 ± 1.335
1.338GlnGly: 1.338 ± 0.498
1.338GlnHis: 1.338 ± 0.692
2.007GlnIle: 2.007 ± 0.532
1.672GlnLys: 1.672 ± 0.538
4.013GlnLeu: 4.013 ± 1.055
0.669GlnMet: 0.669 ± 0.434
1.672GlnAsn: 1.672 ± 0.391
0.0GlnPro: 0.0 ± 0.0
3.344GlnGln: 3.344 ± 1.046
2.007GlnArg: 2.007 ± 0.662
2.007GlnSer: 2.007 ± 0.616
4.013GlnThr: 4.013 ± 0.654
2.676GlnVal: 2.676 ± 0.748
0.669GlnTrp: 0.669 ± 0.362
1.003GlnTyr: 1.003 ± 0.58
0.0GlnXaa: 0.0 ± 0.0
Arg
4.348ArgAla: 4.348 ± 0.86
1.338ArgCys: 1.338 ± 0.894
2.676ArgAsp: 2.676 ± 0.796
4.013ArgGlu: 4.013 ± 0.933
2.341ArgPhe: 2.341 ± 1.411
2.341ArgGly: 2.341 ± 0.849
2.341ArgHis: 2.341 ± 0.701
4.013ArgIle: 4.013 ± 0.48
5.351ArgLys: 5.351 ± 0.571
5.686ArgLeu: 5.686 ± 1.7
1.672ArgMet: 1.672 ± 0.823
3.01ArgAsn: 3.01 ± 0.569
2.341ArgPro: 2.341 ± 0.7
1.672ArgGln: 1.672 ± 0.722
5.351ArgArg: 5.351 ± 2.016
4.348ArgSer: 4.348 ± 1.745
4.013ArgThr: 4.013 ± 1.186
4.682ArgVal: 4.682 ± 1.761
1.003ArgTrp: 1.003 ± 0.308
3.01ArgTyr: 3.01 ± 1.257
0.0ArgXaa: 0.0 ± 0.0
Ser
3.679SerAla: 3.679 ± 0.969
1.003SerCys: 1.003 ± 0.485
3.679SerAsp: 3.679 ± 0.831
4.682SerGlu: 4.682 ± 1.197
2.341SerPhe: 2.341 ± 0.342
3.344SerGly: 3.344 ± 2.207
1.003SerHis: 1.003 ± 0.308
3.679SerIle: 3.679 ± 1.674
5.351SerLys: 5.351 ± 1.413
7.023SerLeu: 7.023 ± 1.309
1.672SerMet: 1.672 ± 0.5
1.672SerAsn: 1.672 ± 0.532
2.341SerPro: 2.341 ± 0.849
2.341SerGln: 2.341 ± 0.365
4.682SerArg: 4.682 ± 0.778
3.01SerSer: 3.01 ± 0.865
4.013SerThr: 4.013 ± 0.548
8.361SerVal: 8.361 ± 1.616
0.669SerTrp: 0.669 ± 0.431
2.007SerTyr: 2.007 ± 0.47
0.0SerXaa: 0.0 ± 0.0
Thr
4.013ThrAla: 4.013 ± 1.037
1.338ThrCys: 1.338 ± 0.649
2.676ThrAsp: 2.676 ± 1.037
3.01ThrGlu: 3.01 ± 0.71
2.676ThrPhe: 2.676 ± 0.905
2.007ThrGly: 2.007 ± 0.39
1.338ThrHis: 1.338 ± 0.488
2.007ThrIle: 2.007 ± 1.232
2.341ThrLys: 2.341 ± 0.712
4.682ThrLeu: 4.682 ± 1.062
1.003ThrMet: 1.003 ± 0.37
2.676ThrAsn: 2.676 ± 0.44
2.341ThrPro: 2.341 ± 0.543
1.672ThrGln: 1.672 ± 1.471
3.01ThrArg: 3.01 ± 1.083
4.348ThrSer: 4.348 ± 1.053
3.344ThrThr: 3.344 ± 1.384
6.689ThrVal: 6.689 ± 0.975
1.672ThrTrp: 1.672 ± 0.472
2.341ThrTyr: 2.341 ± 0.428
0.0ThrXaa: 0.0 ± 0.0
Val
5.351ValAla: 5.351 ± 0.928
1.338ValCys: 1.338 ± 0.503
6.02ValAsp: 6.02 ± 1.033
6.355ValGlu: 6.355 ± 0.714
1.672ValPhe: 1.672 ± 0.56
4.013ValGly: 4.013 ± 1.237
1.672ValHis: 1.672 ± 1.01
4.013ValIle: 4.013 ± 0.558
6.689ValLys: 6.689 ± 1.074
6.02ValLeu: 6.02 ± 1.545
3.01ValMet: 3.01 ± 0.95
3.344ValAsn: 3.344 ± 0.781
2.341ValPro: 2.341 ± 0.594
2.341ValGln: 2.341 ± 0.615
4.682ValArg: 4.682 ± 1.197
7.358ValSer: 7.358 ± 1.242
3.344ValThr: 3.344 ± 0.958
6.355ValVal: 6.355 ± 1.151
1.338ValTrp: 1.338 ± 0.429
4.013ValTyr: 4.013 ± 1.114
0.0ValXaa: 0.0 ± 0.0
Trp
0.669TrpAla: 0.669 ± 0.404
0.669TrpCys: 0.669 ± 0.404
0.334TrpAsp: 0.334 ± 0.202
1.003TrpGlu: 1.003 ± 0.7
0.0TrpPhe: 0.0 ± 0.0
1.338TrpGly: 1.338 ± 0.551
0.0TrpHis: 0.0 ± 0.0
0.669TrpIle: 0.669 ± 0.404
0.669TrpLys: 0.669 ± 0.658
0.669TrpLeu: 0.669 ± 0.671
0.334TrpMet: 0.334 ± 0.344
0.669TrpAsn: 0.669 ± 0.542
0.0TrpPro: 0.0 ± 0.0
1.003TrpGln: 1.003 ± 0.308
0.669TrpArg: 0.669 ± 0.572
1.338TrpSer: 1.338 ± 0.509
0.334TrpThr: 0.334 ± 0.477
0.0TrpVal: 0.0 ± 0.0
0.334TrpTrp: 0.334 ± 0.406
0.669TrpTyr: 0.669 ± 0.404
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.341TyrAla: 2.341 ± 0.782
1.338TyrCys: 1.338 ± 0.438
2.007TyrAsp: 2.007 ± 0.602
2.341TyrGlu: 2.341 ± 1.255
0.669TyrPhe: 0.669 ± 0.362
2.341TyrGly: 2.341 ± 0.543
0.0TyrHis: 0.0 ± 0.0
0.334TyrIle: 0.334 ± 0.336
2.007TyrLys: 2.007 ± 1.022
5.017TyrLeu: 5.017 ± 1.666
0.0TyrMet: 0.0 ± 0.0
3.344TyrAsn: 3.344 ± 1.427
1.672TyrPro: 1.672 ± 0.391
1.003TyrGln: 1.003 ± 0.65
2.341TyrArg: 2.341 ± 0.901
2.007TyrSer: 2.007 ± 0.971
1.003TyrThr: 1.003 ± 0.606
2.341TyrVal: 2.341 ± 0.952
0.334TyrTrp: 0.334 ± 0.329
2.007TyrTyr: 2.007 ± 0.662
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2991 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski