Amino acid dipepetide frequency for Salmonella phage vB_SenS_SE1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.896AlaAla: 11.896 ± 1.359
0.728AlaCys: 0.728 ± 0.285
6.798AlaAsp: 6.798 ± 0.687
6.717AlaGlu: 6.717 ± 0.771
3.723AlaPhe: 3.723 ± 0.479
8.74AlaGly: 8.74 ± 0.832
1.942AlaHis: 1.942 ± 0.398
5.26AlaIle: 5.26 ± 0.704
5.989AlaLys: 5.989 ± 0.756
8.578AlaLeu: 8.578 ± 0.946
2.347AlaMet: 2.347 ± 0.535
4.289AlaAsn: 4.289 ± 0.68
3.156AlaPro: 3.156 ± 0.543
3.884AlaGln: 3.884 ± 0.724
5.098AlaArg: 5.098 ± 0.708
6.312AlaSer: 6.312 ± 0.67
5.827AlaThr: 5.827 ± 0.775
6.798AlaVal: 6.798 ± 0.783
1.619AlaTrp: 1.619 ± 0.31
3.237AlaTyr: 3.237 ± 0.459
0.0AlaXaa: 0.0 ± 0.0
Cys
1.133CysAla: 1.133 ± 0.308
0.324CysCys: 0.324 ± 0.17
0.566CysAsp: 0.566 ± 0.213
0.647CysGlu: 0.647 ± 0.24
0.0CysPhe: 0.0 ± 0.0
1.295CysGly: 1.295 ± 0.344
0.405CysHis: 0.405 ± 0.17
0.324CysIle: 0.324 ± 0.133
0.809CysLys: 0.809 ± 0.231
0.89CysLeu: 0.89 ± 0.318
0.162CysMet: 0.162 ± 0.117
0.647CysAsn: 0.647 ± 0.223
0.486CysPro: 0.486 ± 0.224
0.647CysGln: 0.647 ± 0.261
0.809CysArg: 0.809 ± 0.267
0.162CysSer: 0.162 ± 0.107
0.324CysThr: 0.324 ± 0.162
0.486CysVal: 0.486 ± 0.187
0.243CysTrp: 0.243 ± 0.113
0.486CysTyr: 0.486 ± 0.21
0.0CysXaa: 0.0 ± 0.0
Asp
7.041AspAla: 7.041 ± 0.749
0.647AspCys: 0.647 ± 0.318
3.965AspAsp: 3.965 ± 0.913
5.26AspGlu: 5.26 ± 1.053
2.509AspPhe: 2.509 ± 0.431
4.856AspGly: 4.856 ± 0.606
0.566AspHis: 0.566 ± 0.2
3.804AspIle: 3.804 ± 0.392
4.208AspLys: 4.208 ± 0.507
5.503AspLeu: 5.503 ± 0.734
1.457AspMet: 1.457 ± 0.362
2.913AspAsn: 2.913 ± 0.562
2.023AspPro: 2.023 ± 0.449
1.699AspGln: 1.699 ± 0.404
2.428AspArg: 2.428 ± 0.502
4.208AspSer: 4.208 ± 0.707
3.965AspThr: 3.965 ± 0.53
4.208AspVal: 4.208 ± 0.641
1.052AspTrp: 1.052 ± 0.245
2.104AspTyr: 2.104 ± 0.363
0.0AspXaa: 0.0 ± 0.0
Glu
6.717GluAla: 6.717 ± 0.969
0.486GluCys: 0.486 ± 0.223
4.856GluAsp: 4.856 ± 0.618
4.208GluGlu: 4.208 ± 0.744
2.266GluPhe: 2.266 ± 0.423
4.532GluGly: 4.532 ± 0.514
1.133GluHis: 1.133 ± 0.313
3.237GluIle: 3.237 ± 0.44
3.642GluLys: 3.642 ± 0.497
5.746GluLeu: 5.746 ± 0.946
2.509GluMet: 2.509 ± 0.444
2.59GluAsn: 2.59 ± 0.501
2.266GluPro: 2.266 ± 0.506
2.913GluGln: 2.913 ± 0.548
3.075GluArg: 3.075 ± 0.524
3.48GluSer: 3.48 ± 0.484
3.561GluThr: 3.561 ± 0.544
3.965GluVal: 3.965 ± 0.47
1.133GluTrp: 1.133 ± 0.258
2.104GluTyr: 2.104 ± 0.401
0.0GluXaa: 0.0 ± 0.0
Phe
2.671PheAla: 2.671 ± 0.43
0.486PheCys: 0.486 ± 0.179
2.59PheAsp: 2.59 ± 0.505
2.509PheGlu: 2.509 ± 0.41
0.728PhePhe: 0.728 ± 0.221
2.994PheGly: 2.994 ± 0.529
0.486PheHis: 0.486 ± 0.19
2.509PheIle: 2.509 ± 0.496
1.295PheLys: 1.295 ± 0.253
1.861PheLeu: 1.861 ± 0.467
0.405PheMet: 0.405 ± 0.192
1.942PheAsn: 1.942 ± 0.39
1.376PhePro: 1.376 ± 0.386
0.89PheGln: 0.89 ± 0.222
1.942PheArg: 1.942 ± 0.353
2.509PheSer: 2.509 ± 0.567
2.751PheThr: 2.751 ± 0.67
2.266PheVal: 2.266 ± 0.396
0.971PheTrp: 0.971 ± 0.29
1.052PheTyr: 1.052 ± 0.246
0.0PheXaa: 0.0 ± 0.0
Gly
6.798GlyAla: 6.798 ± 0.785
0.971GlyCys: 0.971 ± 0.313
4.451GlyAsp: 4.451 ± 0.624
4.451GlyGlu: 4.451 ± 0.417
2.509GlyPhe: 2.509 ± 0.427
5.989GlyGly: 5.989 ± 0.992
1.052GlyHis: 1.052 ± 0.286
3.156GlyIle: 3.156 ± 0.513
4.613GlyLys: 4.613 ± 0.546
5.746GlyLeu: 5.746 ± 0.625
2.185GlyMet: 2.185 ± 0.412
4.208GlyAsn: 4.208 ± 0.563
1.78GlyPro: 1.78 ± 0.361
3.399GlyGln: 3.399 ± 0.375
3.965GlyArg: 3.965 ± 0.548
5.746GlySer: 5.746 ± 0.845
4.613GlyThr: 4.613 ± 0.627
6.15GlyVal: 6.15 ± 0.641
1.214GlyTrp: 1.214 ± 0.36
2.671GlyTyr: 2.671 ± 0.447
0.0GlyXaa: 0.0 ± 0.0
His
1.619HisAla: 1.619 ± 0.384
0.486HisCys: 0.486 ± 0.184
0.89HisAsp: 0.89 ± 0.286
0.405HisGlu: 0.405 ± 0.165
0.486HisPhe: 0.486 ± 0.201
0.566HisGly: 0.566 ± 0.215
0.486HisHis: 0.486 ± 0.165
0.809HisIle: 0.809 ± 0.241
1.376HisLys: 1.376 ± 0.364
0.728HisLeu: 0.728 ± 0.29
0.324HisMet: 0.324 ± 0.201
1.052HisAsn: 1.052 ± 0.258
1.376HisPro: 1.376 ± 0.29
1.133HisGln: 1.133 ± 0.291
0.728HisArg: 0.728 ± 0.219
1.133HisSer: 1.133 ± 0.246
0.566HisThr: 0.566 ± 0.189
1.457HisVal: 1.457 ± 0.35
0.081HisTrp: 0.081 ± 0.069
0.566HisTyr: 0.566 ± 0.187
0.0HisXaa: 0.0 ± 0.0
Ile
5.017IleAla: 5.017 ± 0.721
0.809IleCys: 0.809 ± 0.215
3.561IleAsp: 3.561 ± 0.547
3.318IleGlu: 3.318 ± 0.377
1.133IlePhe: 1.133 ± 0.3
3.965IleGly: 3.965 ± 0.628
0.486IleHis: 0.486 ± 0.182
2.913IleIle: 2.913 ± 0.554
2.751IleLys: 2.751 ± 0.476
2.913IleLeu: 2.913 ± 0.513
1.052IleMet: 1.052 ± 0.242
2.266IleAsn: 2.266 ± 0.487
3.075IlePro: 3.075 ± 0.431
2.023IleGln: 2.023 ± 0.354
2.266IleArg: 2.266 ± 0.38
3.561IleSer: 3.561 ± 0.439
4.046IleThr: 4.046 ± 0.523
3.561IleVal: 3.561 ± 0.474
0.647IleTrp: 0.647 ± 0.265
1.538IleTyr: 1.538 ± 0.404
0.0IleXaa: 0.0 ± 0.0
Lys
6.636LysAla: 6.636 ± 0.816
0.728LysCys: 0.728 ± 0.235
2.428LysAsp: 2.428 ± 0.497
3.561LysGlu: 3.561 ± 0.537
2.185LysPhe: 2.185 ± 0.411
3.884LysGly: 3.884 ± 0.554
1.133LysHis: 1.133 ± 0.301
2.509LysIle: 2.509 ± 0.457
2.671LysLys: 2.671 ± 0.35
5.179LysLeu: 5.179 ± 0.761
2.023LysMet: 2.023 ± 0.558
2.266LysAsn: 2.266 ± 0.518
2.913LysPro: 2.913 ± 0.6
2.59LysGln: 2.59 ± 0.431
3.318LysArg: 3.318 ± 0.443
2.751LysSer: 2.751 ± 0.605
3.804LysThr: 3.804 ± 0.617
3.399LysVal: 3.399 ± 0.407
0.89LysTrp: 0.89 ± 0.221
2.104LysTyr: 2.104 ± 0.362
0.0LysXaa: 0.0 ± 0.0
Leu
8.254LeuAla: 8.254 ± 0.816
0.809LeuCys: 0.809 ± 0.263
4.856LeuAsp: 4.856 ± 0.576
4.856LeuGlu: 4.856 ± 0.574
1.942LeuPhe: 1.942 ± 0.399
4.532LeuGly: 4.532 ± 0.555
0.971LeuHis: 0.971 ± 0.289
3.642LeuIle: 3.642 ± 0.482
5.584LeuLys: 5.584 ± 0.705
5.908LeuLeu: 5.908 ± 0.724
1.699LeuMet: 1.699 ± 0.324
4.289LeuAsn: 4.289 ± 0.646
3.399LeuPro: 3.399 ± 0.596
3.318LeuGln: 3.318 ± 0.507
4.856LeuArg: 4.856 ± 0.625
4.532LeuSer: 4.532 ± 0.673
4.289LeuThr: 4.289 ± 0.636
5.989LeuVal: 5.989 ± 0.714
0.566LeuTrp: 0.566 ± 0.188
1.78LeuTyr: 1.78 ± 0.277
0.0LeuXaa: 0.0 ± 0.0
Met
2.913MetAla: 2.913 ± 0.437
0.405MetCys: 0.405 ± 0.173
1.538MetAsp: 1.538 ± 0.396
1.538MetGlu: 1.538 ± 0.33
1.133MetPhe: 1.133 ± 0.292
1.78MetGly: 1.78 ± 0.392
0.566MetHis: 0.566 ± 0.194
0.971MetIle: 0.971 ± 0.279
1.376MetLys: 1.376 ± 0.321
1.78MetLeu: 1.78 ± 0.336
0.728MetMet: 0.728 ± 0.278
0.809MetAsn: 0.809 ± 0.214
0.728MetPro: 0.728 ± 0.196
0.971MetGln: 0.971 ± 0.252
1.538MetArg: 1.538 ± 0.337
1.538MetSer: 1.538 ± 0.332
2.104MetThr: 2.104 ± 0.361
1.538MetVal: 1.538 ± 0.399
0.324MetTrp: 0.324 ± 0.137
0.647MetTyr: 0.647 ± 0.333
0.0MetXaa: 0.0 ± 0.0
Asn
4.208AsnAla: 4.208 ± 0.651
0.566AsnCys: 0.566 ± 0.213
4.37AsnAsp: 4.37 ± 0.483
2.913AsnGlu: 2.913 ± 0.466
1.538AsnPhe: 1.538 ± 0.311
5.26AsnGly: 5.26 ± 0.701
0.89AsnHis: 0.89 ± 0.216
3.075AsnIle: 3.075 ± 0.515
2.347AsnLys: 2.347 ± 0.453
2.832AsnLeu: 2.832 ± 0.373
0.647AsnMet: 0.647 ± 0.225
2.832AsnAsn: 2.832 ± 0.522
1.78AsnPro: 1.78 ± 0.467
1.376AsnGln: 1.376 ± 0.343
1.942AsnArg: 1.942 ± 0.474
2.751AsnSer: 2.751 ± 0.479
2.428AsnThr: 2.428 ± 0.56
3.156AsnVal: 3.156 ± 0.485
0.809AsnTrp: 0.809 ± 0.301
1.861AsnTyr: 1.861 ± 0.403
0.0AsnXaa: 0.0 ± 0.0
Pro
4.127ProAla: 4.127 ± 0.702
0.486ProCys: 0.486 ± 0.184
3.237ProAsp: 3.237 ± 0.388
4.208ProGlu: 4.208 ± 0.641
1.619ProPhe: 1.619 ± 0.416
2.671ProGly: 2.671 ± 0.591
0.324ProHis: 0.324 ± 0.144
1.538ProIle: 1.538 ± 0.299
1.78ProLys: 1.78 ± 0.411
2.913ProLeu: 2.913 ± 0.515
1.214ProMet: 1.214 ± 0.286
1.942ProAsn: 1.942 ± 0.407
0.89ProPro: 0.89 ± 0.288
1.538ProGln: 1.538 ± 0.355
1.619ProArg: 1.619 ± 0.369
2.023ProSer: 2.023 ± 0.387
2.023ProThr: 2.023 ± 0.372
3.561ProVal: 3.561 ± 0.464
0.243ProTrp: 0.243 ± 0.147
1.457ProTyr: 1.457 ± 0.33
0.0ProXaa: 0.0 ± 0.0
Gln
4.532GlnAla: 4.532 ± 0.661
0.243GlnCys: 0.243 ± 0.124
2.509GlnAsp: 2.509 ± 0.449
2.185GlnGlu: 2.185 ± 0.428
1.376GlnPhe: 1.376 ± 0.337
2.023GlnGly: 2.023 ± 0.434
0.971GlnHis: 0.971 ± 0.315
3.075GlnIle: 3.075 ± 0.515
2.347GlnLys: 2.347 ± 0.588
2.913GlnLeu: 2.913 ± 0.424
1.376GlnMet: 1.376 ± 0.273
2.023GlnAsn: 2.023 ± 0.38
2.509GlnPro: 2.509 ± 0.425
2.751GlnGln: 2.751 ± 0.7
2.671GlnArg: 2.671 ± 0.45
1.699GlnSer: 1.699 ± 0.341
2.428GlnThr: 2.428 ± 0.496
2.509GlnVal: 2.509 ± 0.364
0.728GlnTrp: 0.728 ± 0.248
1.699GlnTyr: 1.699 ± 0.365
0.0GlnXaa: 0.0 ± 0.0
Arg
5.26ArgAla: 5.26 ± 0.572
0.566ArgCys: 0.566 ± 0.241
3.237ArgAsp: 3.237 ± 0.539
3.156ArgGlu: 3.156 ± 0.455
1.619ArgPhe: 1.619 ± 0.297
3.884ArgGly: 3.884 ± 0.421
0.89ArgHis: 0.89 ± 0.271
2.671ArgIle: 2.671 ± 0.396
3.237ArgLys: 3.237 ± 0.701
3.884ArgLeu: 3.884 ± 0.575
1.214ArgMet: 1.214 ± 0.312
3.318ArgAsn: 3.318 ± 0.479
1.942ArgPro: 1.942 ± 0.44
3.318ArgGln: 3.318 ± 0.509
3.399ArgArg: 3.399 ± 0.543
2.185ArgSer: 2.185 ± 0.33
2.832ArgThr: 2.832 ± 0.527
4.046ArgVal: 4.046 ± 0.519
0.647ArgTrp: 0.647 ± 0.261
1.376ArgTyr: 1.376 ± 0.375
0.0ArgXaa: 0.0 ± 0.0
Ser
6.393SerAla: 6.393 ± 1.057
0.162SerCys: 0.162 ± 0.099
3.561SerAsp: 3.561 ± 0.475
3.156SerGlu: 3.156 ± 0.678
3.075SerPhe: 3.075 ± 0.455
5.017SerGly: 5.017 ± 0.763
1.133SerHis: 1.133 ± 0.344
2.59SerIle: 2.59 ± 0.442
3.156SerLys: 3.156 ± 0.459
4.856SerLeu: 4.856 ± 0.471
1.295SerMet: 1.295 ± 0.31
2.509SerAsn: 2.509 ± 0.373
2.509SerPro: 2.509 ± 0.442
2.185SerGln: 2.185 ± 0.642
3.075SerArg: 3.075 ± 0.426
2.751SerSer: 2.751 ± 0.492
4.775SerThr: 4.775 ± 0.648
4.289SerVal: 4.289 ± 0.788
0.971SerTrp: 0.971 ± 0.238
1.861SerTyr: 1.861 ± 0.364
0.0SerXaa: 0.0 ± 0.0
Thr
6.393ThrAla: 6.393 ± 0.793
0.566ThrCys: 0.566 ± 0.204
2.994ThrAsp: 2.994 ± 0.484
3.48ThrGlu: 3.48 ± 0.507
2.671ThrPhe: 2.671 ± 0.579
6.069ThrGly: 6.069 ± 0.851
0.566ThrHis: 0.566 ± 0.214
3.075ThrIle: 3.075 ± 0.412
2.671ThrLys: 2.671 ± 0.509
5.341ThrLeu: 5.341 ± 0.719
1.538ThrMet: 1.538 ± 0.362
1.861ThrAsn: 1.861 ± 0.348
3.399ThrPro: 3.399 ± 0.567
2.428ThrGln: 2.428 ± 0.455
3.156ThrArg: 3.156 ± 0.374
4.208ThrSer: 4.208 ± 0.684
4.046ThrThr: 4.046 ± 0.71
5.098ThrVal: 5.098 ± 0.609
0.809ThrTrp: 0.809 ± 0.246
2.104ThrTyr: 2.104 ± 0.458
0.0ThrXaa: 0.0 ± 0.0
Val
7.283ValAla: 7.283 ± 0.847
0.647ValCys: 0.647 ± 0.216
4.613ValAsp: 4.613 ± 0.447
4.775ValGlu: 4.775 ± 0.639
1.942ValPhe: 1.942 ± 0.5
3.723ValGly: 3.723 ± 0.401
0.971ValHis: 0.971 ± 0.248
4.289ValIle: 4.289 ± 0.516
4.208ValLys: 4.208 ± 0.555
4.775ValLeu: 4.775 ± 0.544
1.376ValMet: 1.376 ± 0.39
3.642ValAsn: 3.642 ± 0.609
2.266ValPro: 2.266 ± 0.516
3.075ValGln: 3.075 ± 0.453
4.046ValArg: 4.046 ± 0.498
4.856ValSer: 4.856 ± 0.705
5.179ValThr: 5.179 ± 0.639
4.694ValVal: 4.694 ± 0.788
1.133ValTrp: 1.133 ± 0.281
2.832ValTyr: 2.832 ± 0.444
0.0ValXaa: 0.0 ± 0.0
Trp
1.052TrpAla: 1.052 ± 0.291
0.162TrpCys: 0.162 ± 0.112
1.133TrpAsp: 1.133 ± 0.349
0.647TrpGlu: 0.647 ± 0.237
0.486TrpPhe: 0.486 ± 0.223
0.728TrpGly: 0.728 ± 0.214
0.486TrpHis: 0.486 ± 0.209
0.324TrpIle: 0.324 ± 0.129
0.566TrpLys: 0.566 ± 0.236
1.699TrpLeu: 1.699 ± 0.357
0.324TrpMet: 0.324 ± 0.164
0.809TrpAsn: 0.809 ± 0.257
0.486TrpPro: 0.486 ± 0.191
0.89TrpGln: 0.89 ± 0.256
0.971TrpArg: 0.971 ± 0.244
0.971TrpSer: 0.971 ± 0.302
1.052TrpThr: 1.052 ± 0.238
1.457TrpVal: 1.457 ± 0.335
0.243TrpTrp: 0.243 ± 0.124
0.486TrpTyr: 0.486 ± 0.203
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.994TyrAla: 2.994 ± 0.512
0.566TyrCys: 0.566 ± 0.202
2.266TyrAsp: 2.266 ± 0.509
2.428TyrGlu: 2.428 ± 0.397
1.295TyrPhe: 1.295 ± 0.353
3.156TyrGly: 3.156 ± 0.575
0.809TyrHis: 0.809 ± 0.241
1.133TyrIle: 1.133 ± 0.279
2.347TyrLys: 2.347 ± 0.467
2.023TyrLeu: 2.023 ± 0.292
0.971TyrMet: 0.971 ± 0.23
1.376TyrAsn: 1.376 ± 0.243
1.052TyrPro: 1.052 ± 0.34
1.538TyrGln: 1.538 ± 0.489
1.78TyrArg: 1.78 ± 0.369
1.942TyrSer: 1.942 ± 0.337
1.861TyrThr: 1.861 ± 0.423
1.78TyrVal: 1.78 ± 0.442
0.647TyrTrp: 0.647 ± 0.232
1.052TyrTyr: 1.052 ± 0.245
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 63 proteins (12358 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski