Amino acid dipepetide frequency for Romboutsia hominis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	2.932AlaAla: 2.932 ± 0.085	0.704AlaCys: 0.704 ± 0.029	2.443AlaAsp: 2.443 ± 0.127	2.581AlaGlu: 2.581 ± 0.064	2.228AlaPhe: 2.228 ± 0.061	3.547AlaGly: 3.547 ± 0.081	0.797AlaHis: 0.797 ± 0.031	6.02AlaIle: 6.02 ± 0.095	4.939AlaLys: 4.939 ± 0.082	5.516AlaLeu: 5.516 ± 0.099	1.735AlaMet: 1.735 ± 0.044	2.864AlaAsn: 2.864 ± 0.065	1.341AlaPro: 1.341 ± 0.046	1.404AlaGln: 1.404 ± 0.046	1.776AlaArg: 1.776 ± 0.054	3.384AlaSer: 3.384 ± 0.068	3.017AlaThr: 3.017 ± 0.089	3.521AlaVal: 3.521 ± 0.081	0.291AlaTrp: 0.291 ± 0.022	2.047AlaTyr: 2.047 ± 0.056	0.0AlaXaa: 0.0 ± 0.0
Cys	0.649CysAla: 0.649 ± 0.03	0.193CysCys: 0.193 ± 0.021	0.763CysAsp: 0.763 ± 0.03	0.893CysGlu: 0.893 ± 0.041	0.401CysPhe: 0.401 ± 0.023	1.105CysGly: 1.105 ± 0.041	0.194CysHis: 0.194 ± 0.017	1.203CysIle: 1.203 ± 0.037	1.03CysLys: 1.03 ± 0.039	0.838CysLeu: 0.838 ± 0.034	0.348CysMet: 0.348 ± 0.021	0.697CysAsn: 0.697 ± 0.028	0.453CysPro: 0.453 ± 0.029	0.22CysGln: 0.22 ± 0.019	0.35CysArg: 0.35 ± 0.021	0.785CysSer: 0.785 ± 0.03	0.529CysThr: 0.529 ± 0.024	0.693CysVal: 0.693 ± 0.031	0.05CysTrp: 0.05 ± 0.007	0.382CysTyr: 0.382 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	2.762AspAla: 2.762 ± 0.161	0.619AspCys: 0.619 ± 0.037	2.894AspAsp: 2.894 ± 0.061	4.822AspGlu: 4.822 ± 0.069	2.598AspPhe: 2.598 ± 0.059	3.119AspGly: 3.119 ± 0.065	0.583AspHis: 0.583 ± 0.026	7.333AspIle: 7.333 ± 0.098	6.295AspLys: 6.295 ± 0.094	5.037AspLeu: 5.037 ± 0.086	1.672AspMet: 1.672 ± 0.044	3.58AspAsn: 3.58 ± 0.069	1.218AspPro: 1.218 ± 0.046	0.774AspGln: 0.774 ± 0.031	1.909AspArg: 1.909 ± 0.044	3.131AspSer: 3.131 ± 0.112	2.554AspThr: 2.554 ± 0.05	3.683AspVal: 3.683 ± 0.075	0.297AspTrp: 0.297 ± 0.021	2.808AspTyr: 2.808 ± 0.067	0.0AspXaa: 0.0 ± 0.0
Glu	3.837GluAla: 3.837 ± 0.081	0.798GluCys: 0.798 ± 0.032	4.592GluAsp: 4.592 ± 0.086	7.072GluGlu: 7.072 ± 0.12	3.11GluPhe: 3.11 ± 0.057	3.984GluGly: 3.984 ± 0.078	0.924GluHis: 0.924 ± 0.033	7.391GluIle: 7.391 ± 0.106	7.359GluLys: 7.359 ± 0.101	6.717GluLeu: 6.717 ± 0.095	1.808GluMet: 1.808 ± 0.05	5.69GluAsn: 5.69 ± 0.077	1.279GluPro: 1.279 ± 0.04	1.529GluGln: 1.529 ± 0.048	2.318GluArg: 2.318 ± 0.058	3.757GluSer: 3.757 ± 0.068	2.778GluThr: 2.778 ± 0.052	5.194GluVal: 5.194 ± 0.095	0.336GluTrp: 0.336 ± 0.022	3.226GluTyr: 3.226 ± 0.063	0.0GluXaa: 0.0 ± 0.0
Phe	2.229PheAla: 2.229 ± 0.063	0.484PheCys: 0.484 ± 0.023	2.466PheAsp: 2.466 ± 0.061	2.787PheGlu: 2.787 ± 0.059	1.793PhePhe: 1.793 ± 0.054	2.784PheGly: 2.784 ± 0.073	0.438PheHis: 0.438 ± 0.024	4.89PheIle: 4.89 ± 0.106	3.765PheLys: 3.765 ± 0.068	3.747PheLeu: 3.747 ± 0.075	1.223PheMet: 1.223 ± 0.037	2.881PheAsn: 2.881 ± 0.061	0.926PhePro: 0.926 ± 0.036	0.584PheGln: 0.584 ± 0.025	1.17PheArg: 1.17 ± 0.038	2.761PheSer: 2.761 ± 0.067	2.192PheThr: 2.192 ± 0.047	2.643PheVal: 2.643 ± 0.061	0.231PheTrp: 0.231 ± 0.014	1.629PheTyr: 1.629 ± 0.049	0.0PheXaa: 0.0 ± 0.0
Gly	3.898GlyAla: 3.898 ± 0.089	1.031GlyCys: 1.031 ± 0.043	3.014GlyAsp: 3.014 ± 0.07	3.968GlyGlu: 3.968 ± 0.086	2.979GlyPhe: 2.979 ± 0.065	4.271GlyGly: 4.271 ± 0.09	1.029GlyHis: 1.029 ± 0.04	6.893GlyIle: 6.893 ± 0.102	5.309GlyLys: 5.309 ± 0.086	5.624GlyLeu: 5.624 ± 0.09	1.853GlyMet: 1.853 ± 0.047	3.266GlyAsn: 3.266 ± 0.073	1.372GlyPro: 1.372 ± 0.072	1.486GlyGln: 1.486 ± 0.046	1.996GlyArg: 1.996 ± 0.047	3.747GlySer: 3.747 ± 0.077	3.131GlyThr: 3.131 ± 0.065	4.735GlyVal: 4.735 ± 0.084	0.404GlyTrp: 0.404 ± 0.025	2.993GlyTyr: 2.993 ± 0.059	0.0GlyXaa: 0.0 ± 0.0
His	0.659HisAla: 0.659 ± 0.034	0.181HisCys: 0.181 ± 0.015	0.723HisAsp: 0.723 ± 0.032	0.934HisGlu: 0.934 ± 0.037	0.554HisPhe: 0.554 ± 0.025	0.957HisGly: 0.957 ± 0.037	0.257HisHis: 0.257 ± 0.019	1.489HisIle: 1.489 ± 0.043	1.117HisLys: 1.117 ± 0.037	1.153HisLeu: 1.153 ± 0.039	0.386HisMet: 0.386 ± 0.022	0.838HisAsn: 0.838 ± 0.033	0.605HisPro: 0.605 ± 0.025	0.334HisGln: 0.334 ± 0.023	0.501HisArg: 0.501 ± 0.022	0.839HisSer: 0.839 ± 0.036	0.729HisThr: 0.729 ± 0.028	0.758HisVal: 0.758 ± 0.03	0.097HisTrp: 0.097 ± 0.008	0.509HisTyr: 0.509 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.89IleAla: 5.89 ± 0.094	1.285IleCys: 1.285 ± 0.038	6.954IleAsp: 6.954 ± 0.1	7.648IleGlu: 7.648 ± 0.112	4.104IlePhe: 4.104 ± 0.089	6.792IleGly: 6.792 ± 0.112	1.346IleHis: 1.346 ± 0.04	9.9IleIle: 9.9 ± 0.149	9.624IleLys: 9.624 ± 0.146	9.546IleLeu: 9.546 ± 0.127	2.387IleMet: 2.387 ± 0.053	7.147IleAsn: 7.147 ± 0.125	3.299IlePro: 3.299 ± 0.071	2.123IleGln: 2.123 ± 0.05	2.99IleArg: 2.99 ± 0.062	7.491IleSer: 7.491 ± 0.127	4.742IleThr: 4.742 ± 0.083	6.813IleVal: 6.813 ± 0.105	0.498IleTrp: 0.498 ± 0.028	4.078IleTyr: 4.078 ± 0.096	0.0IleXaa: 0.0 ± 0.0
Lys	4.481LysAla: 4.481 ± 0.079	0.894LysCys: 0.894 ± 0.043	6.604LysAsp: 6.604 ± 0.107	9.754LysGlu: 9.754 ± 0.127	3.322LysPhe: 3.322 ± 0.07	5.032LysGly: 5.032 ± 0.093	1.237LysHis: 1.237 ± 0.036	8.372LysIle: 8.372 ± 0.111	8.423LysLys: 8.423 ± 0.132	7.792LysLeu: 7.792 ± 0.093	2.57LysMet: 2.57 ± 0.055	7.103LysAsn: 7.103 ± 0.113	2.05LysPro: 2.05 ± 0.054	2.071LysGln: 2.071 ± 0.054	2.851LysArg: 2.851 ± 0.063	5.677LysSer: 5.677 ± 0.088	3.987LysThr: 3.987 ± 0.071	6.123LysVal: 6.123 ± 0.094	0.508LysTrp: 0.508 ± 0.024	4.523LysTyr: 4.523 ± 0.091	0.0LysXaa: 0.0 ± 0.0
Leu	5.162LeuAla: 5.162 ± 0.097	1.042LeuCys: 1.042 ± 0.038	5.773LeuAsp: 5.773 ± 0.075	6.599LeuGlu: 6.599 ± 0.095	3.661LeuPhe: 3.661 ± 0.067	6.343LeuGly: 6.343 ± 0.094	1.044LeuHis: 1.044 ± 0.035	8.28LeuIle: 8.28 ± 0.119	8.292LeuLys: 8.292 ± 0.094	7.559LeuLeu: 7.559 ± 0.103	2.263LeuMet: 2.263 ± 0.058	6.046LeuAsn: 6.046 ± 0.094	2.544LeuPro: 2.544 ± 0.062	1.823LeuGln: 1.823 ± 0.055	2.887LeuArg: 2.887 ± 0.06	6.677LeuSer: 6.677 ± 0.103	4.246LeuThr: 4.246 ± 0.072	5.964LeuVal: 5.964 ± 0.096	0.445LeuTrp: 0.445 ± 0.025	3.327LeuTyr: 3.327 ± 0.072	0.0LeuXaa: 0.0 ± 0.0
Met	1.809MetAla: 1.809 ± 0.058	0.282MetCys: 0.282 ± 0.018	1.557MetAsp: 1.557 ± 0.046	1.648MetGlu: 1.648 ± 0.045	1.059MetPhe: 1.059 ± 0.034	1.875MetGly: 1.875 ± 0.058	0.356MetHis: 0.356 ± 0.019	2.524MetIle: 2.524 ± 0.052	2.531MetLys: 2.531 ± 0.05	2.306MetLeu: 2.306 ± 0.055	0.803MetMet: 0.803 ± 0.036	1.737MetAsn: 1.737 ± 0.044	0.889MetPro: 0.889 ± 0.035	0.664MetGln: 0.664 ± 0.03	0.901MetArg: 0.901 ± 0.031	1.851MetSer: 1.851 ± 0.053	1.306MetThr: 1.306 ± 0.045	1.615MetVal: 1.615 ± 0.049	0.135MetTrp: 0.135 ± 0.013	0.969MetTyr: 0.969 ± 0.033	0.0MetXaa: 0.0 ± 0.0
Asn	2.866AsnAla: 2.866 ± 0.068	0.695AsnCys: 0.695 ± 0.033	3.216AsnAsp: 3.216 ± 0.06	4.74AsnGlu: 4.74 ± 0.082	2.477AsnPhe: 2.477 ± 0.055	3.41AsnGly: 3.41 ± 0.066	0.922AsnHis: 0.922 ± 0.03	8.44AsnIle: 8.44 ± 0.138	6.971AsnLys: 6.971 ± 0.119	6.172AsnLeu: 6.172 ± 0.09	1.813AsnMet: 1.813 ± 0.047	4.864AsnAsn: 4.864 ± 0.098	2.257AsnPro: 2.257 ± 0.054	1.589AsnGln: 1.589 ± 0.047	1.877AsnArg: 1.877 ± 0.045	3.799AsnSer: 3.799 ± 0.081	3.219AsnThr: 3.219 ± 0.069	3.779AsnVal: 3.779 ± 0.069	0.367AsnTrp: 0.367 ± 0.024	2.766AsnTyr: 2.766 ± 0.066	0.0AsnXaa: 0.0 ± 0.0
Pro	1.326ProAla: 1.326 ± 0.05	0.288ProCys: 0.288 ± 0.018	1.27ProAsp: 1.27 ± 0.036	1.784ProGlu: 1.784 ± 0.047	1.299ProPhe: 1.299 ± 0.04	1.673ProGly: 1.673 ± 0.054	0.481ProHis: 0.481 ± 0.024	2.908ProIle: 2.908 ± 0.064	2.327ProLys: 2.327 ± 0.063	2.198ProLeu: 2.198 ± 0.051	0.755ProMet: 0.755 ± 0.031	1.616ProAsn: 1.616 ± 0.043	0.562ProPro: 0.562 ± 0.031	0.839ProGln: 0.839 ± 0.032	0.798ProArg: 0.798 ± 0.033	1.783ProSer: 1.783 ± 0.051	1.545ProThr: 1.545 ± 0.049	1.919ProVal: 1.919 ± 0.057	0.197ProTrp: 0.197 ± 0.017	1.218ProTyr: 1.218 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	1.3GlnAla: 1.3 ± 0.04	0.219GlnCys: 0.219 ± 0.017	1.171GlnAsp: 1.171 ± 0.046	1.623GlnGlu: 1.623 ± 0.048	0.847GlnPhe: 0.847 ± 0.032	1.537GlnGly: 1.537 ± 0.062	0.291GlnHis: 0.291 ± 0.018	2.119GlnIle: 2.119 ± 0.052	1.949GlnLys: 1.949 ± 0.045	1.846GlnLeu: 1.846 ± 0.052	0.689GlnMet: 0.689 ± 0.028	1.466GlnAsn: 1.466 ± 0.046	0.571GlnPro: 0.571 ± 0.03	0.59GlnGln: 0.59 ± 0.036	0.896GlnArg: 0.896 ± 0.033	1.294GlnSer: 1.294 ± 0.04	1.03GlnThr: 1.03 ± 0.035	1.474GlnVal: 1.474 ± 0.042	0.136GlnTrp: 0.136 ± 0.013	0.844GlnTyr: 0.844 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	1.646ArgAla: 1.646 ± 0.05	0.417ArgCys: 0.417 ± 0.021	1.815ArgAsp: 1.815 ± 0.046	2.736ArgGlu: 2.736 ± 0.055	1.318ArgPhe: 1.318 ± 0.039	1.9ArgGly: 1.9 ± 0.056	0.496ArgHis: 0.496 ± 0.028	2.721ArgIle: 2.721 ± 0.064	2.893ArgLys: 2.893 ± 0.066	2.87ArgLeu: 2.87 ± 0.06	0.823ArgMet: 0.823 ± 0.033	1.949ArgAsn: 1.949 ± 0.048	0.86ArgPro: 0.86 ± 0.037	0.811ArgGln: 0.811 ± 0.031	1.313ArgArg: 1.313 ± 0.05	1.448ArgSer: 1.448 ± 0.041	1.341ArgThr: 1.341 ± 0.045	2.216ArgVal: 2.216 ± 0.053	0.188ArgTrp: 0.188 ± 0.017	1.478ArgTyr: 1.478 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	3.061SerAla: 3.061 ± 0.07	0.661SerCys: 0.661 ± 0.031	3.334SerAsp: 3.334 ± 0.131	3.756SerGlu: 3.756 ± 0.07	2.82SerPhe: 2.82 ± 0.059	3.899SerGly: 3.899 ± 0.072	0.939SerHis: 0.939 ± 0.038	7.372SerIle: 7.372 ± 0.122	6.397SerLys: 6.397 ± 0.098	6.022SerLeu: 6.022 ± 0.095	1.736SerMet: 1.736 ± 0.045	4.151SerAsn: 4.151 ± 0.09	1.574SerPro: 1.574 ± 0.049	1.661SerGln: 1.661 ± 0.042	2.001SerArg: 2.001 ± 0.047	4.309SerSer: 4.309 ± 0.087	3.279SerThr: 3.279 ± 0.086	3.843SerVal: 3.843 ± 0.062	0.332SerTrp: 0.332 ± 0.022	2.592SerTyr: 2.592 ± 0.055	0.0SerXaa: 0.0 ± 0.0
Thr	2.511ThrAla: 2.511 ± 0.078	0.504ThrCys: 0.504 ± 0.022	2.263ThrAsp: 2.263 ± 0.048	2.462ThrGlu: 2.462 ± 0.054	2.04ThrPhe: 2.04 ± 0.049	3.256ThrGly: 3.256 ± 0.071	0.8ThrHis: 0.8 ± 0.033	5.058ThrIle: 5.058 ± 0.07	4.086ThrLys: 4.086 ± 0.066	4.724ThrLeu: 4.724 ± 0.083	1.132ThrMet: 1.132 ± 0.038	2.973ThrAsn: 2.973 ± 0.073	1.797ThrPro: 1.797 ± 0.049	1.18ThrGln: 1.18 ± 0.036	1.379ThrArg: 1.379 ± 0.042	3.29ThrSer: 3.29 ± 0.101	2.749ThrThr: 2.749 ± 0.067	3.174ThrVal: 3.174 ± 0.066	0.324ThrTrp: 0.324 ± 0.019	2.009ThrTyr: 2.009 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	3.926ValAla: 3.926 ± 0.091	0.939ValCys: 0.939 ± 0.033	4.079ValAsp: 4.079 ± 0.073	4.508ValGlu: 4.508 ± 0.082	2.915ValPhe: 2.915 ± 0.057	4.722ValGly: 4.722 ± 0.075	0.841ValHis: 0.841 ± 0.034	6.253ValIle: 6.253 ± 0.093	5.478ValLys: 5.478 ± 0.091	6.078ValLeu: 6.078 ± 0.099	1.574ValMet: 1.574 ± 0.047	3.979ValAsn: 3.979 ± 0.079	1.872ValPro: 1.872 ± 0.046	1.275ValGln: 1.275 ± 0.041	1.891ValArg: 1.891 ± 0.05	4.583ValSer: 4.583 ± 0.062	2.966ValThr: 2.966 ± 0.064	4.936ValVal: 4.936 ± 0.095	0.33ValTrp: 0.33 ± 0.023	2.553ValTyr: 2.553 ± 0.061	0.0ValXaa: 0.0 ± 0.0
Trp	0.291TrpAla: 0.291 ± 0.019	0.064TrpCys: 0.064 ± 0.009	0.326TrpAsp: 0.326 ± 0.023	0.356TrpGlu: 0.356 ± 0.023	0.249TrpPhe: 0.249 ± 0.021	0.39TrpGly: 0.39 ± 0.025	0.095TrpHis: 0.095 ± 0.011	0.583TrpIle: 0.583 ± 0.032	0.367TrpLys: 0.367 ± 0.02	0.504TrpLeu: 0.504 ± 0.026	0.157TrpMet: 0.157 ± 0.015	0.336TrpAsn: 0.336 ± 0.02	0.14TrpPro: 0.14 ± 0.013	0.15TrpGln: 0.15 ± 0.016	0.165TrpArg: 0.165 ± 0.016	0.373TrpSer: 0.373 ± 0.023	0.253TrpThr: 0.253 ± 0.016	0.369TrpVal: 0.369 ± 0.02	0.069TrpTrp: 0.069 ± 0.009	0.237TrpTyr: 0.237 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.849TyrAla: 1.849 ± 0.047	0.477TyrCys: 0.477 ± 0.024	2.432TyrAsp: 2.432 ± 0.053	3.029TyrGlu: 3.029 ± 0.069	1.851TyrPhe: 1.851 ± 0.062	2.405TyrGly: 2.405 ± 0.061	0.552TyrHis: 0.552 ± 0.027	4.907TyrIle: 4.907 ± 0.085	4.223TyrLys: 4.223 ± 0.085	3.726TyrLeu: 3.726 ± 0.076	1.09TyrMet: 1.09 ± 0.035	3.056TyrAsn: 3.056 ± 0.074	1.178TyrPro: 1.178 ± 0.042	0.784TyrGln: 0.784 ± 0.031	1.27TyrArg: 1.27 ± 0.04	2.756TyrSer: 2.756 ± 0.063	2.122TyrThr: 2.122 ± 0.054	2.244TyrVal: 2.244 ± 0.052	0.238TyrTrp: 0.238 ± 0.016	1.712TyrTyr: 1.712 ± 0.052	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2851 proteins (844586 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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