Amino acid dipepetide frequency for Olleya aquimaris

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.717AlaAla: 3.717 ± 0.079	0.559AlaCys: 0.559 ± 0.028	3.285AlaAsp: 3.285 ± 0.068	4.008AlaGlu: 4.008 ± 0.074	3.427AlaPhe: 3.427 ± 0.056	3.843AlaGly: 3.843 ± 0.084	1.079AlaHis: 1.079 ± 0.037	5.606AlaIle: 5.606 ± 0.087	4.967AlaLys: 4.967 ± 0.082	6.335AlaLeu: 6.335 ± 0.091	1.363AlaMet: 1.363 ± 0.045	3.818AlaAsn: 3.818 ± 0.07	1.756AlaPro: 1.756 ± 0.047	2.5AlaGln: 2.5 ± 0.052	1.758AlaArg: 1.758 ± 0.048	4.19AlaSer: 4.19 ± 0.07	3.906AlaThr: 3.906 ± 0.09	3.787AlaVal: 3.787 ± 0.073	0.567AlaTrp: 0.567 ± 0.029	2.485AlaTyr: 2.485 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.452CysAla: 0.452 ± 0.025	0.097CysCys: 0.097 ± 0.011	0.521CysAsp: 0.521 ± 0.031	0.43CysGlu: 0.43 ± 0.024	0.42CysPhe: 0.42 ± 0.026	0.636CysGly: 0.636 ± 0.029	0.181CysHis: 0.181 ± 0.017	0.551CysIle: 0.551 ± 0.025	0.508CysLys: 0.508 ± 0.025	0.636CysLeu: 0.636 ± 0.029	0.114CysMet: 0.114 ± 0.012	0.461CysAsn: 0.461 ± 0.026	0.357CysPro: 0.357 ± 0.025	0.251CysGln: 0.251 ± 0.015	0.158CysArg: 0.158 ± 0.013	0.506CysSer: 0.506 ± 0.026	0.398CysThr: 0.398 ± 0.023	0.484CysVal: 0.484 ± 0.026	0.07CysTrp: 0.07 ± 0.013	0.293CysTyr: 0.293 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	4.216AspAla: 4.216 ± 0.081	0.511AspCys: 0.511 ± 0.03	3.339AspAsp: 3.339 ± 0.077	3.433AspGlu: 3.433 ± 0.07	3.725AspPhe: 3.725 ± 0.074	3.897AspGly: 3.897 ± 0.092	0.891AspHis: 0.891 ± 0.035	4.851AspIle: 4.851 ± 0.066	4.284AspLys: 4.284 ± 0.079	5.468AspLeu: 5.468 ± 0.078	1.137AspMet: 1.137 ± 0.036	4.123AspAsn: 4.123 ± 0.07	1.57AspPro: 1.57 ± 0.044	1.886AspGln: 1.886 ± 0.056	1.705AspArg: 1.705 ± 0.043	3.259AspSer: 3.259 ± 0.077	3.408AspThr: 3.408 ± 0.06	4.084AspVal: 4.084 ± 0.069	0.723AspTrp: 0.723 ± 0.034	3.041AspTyr: 3.041 ± 0.07	0.0AspXaa: 0.0 ± 0.0
Glu	4.811GluAla: 4.811 ± 0.084	0.319GluCys: 0.319 ± 0.024	4.144GluAsp: 4.144 ± 0.074	4.449GluGlu: 4.449 ± 0.09	2.858GluPhe: 2.858 ± 0.073	3.55GluGly: 3.55 ± 0.066	1.145GluHis: 1.145 ± 0.038	4.755GluIle: 4.755 ± 0.077	4.852GluLys: 4.852 ± 0.099	5.671GluLeu: 5.671 ± 0.098	1.249GluMet: 1.249 ± 0.039	4.157GluAsn: 4.157 ± 0.074	1.485GluPro: 1.485 ± 0.048	2.375GluGln: 2.375 ± 0.05	2.154GluArg: 2.154 ± 0.056	2.995GluSer: 2.995 ± 0.063	4.105GluThr: 4.105 ± 0.073	4.438GluVal: 4.438 ± 0.071	0.506GluTrp: 0.506 ± 0.026	2.202GluTyr: 2.202 ± 0.051	0.0GluXaa: 0.0 ± 0.0
Phe	2.929PheAla: 2.929 ± 0.059	0.452PheCys: 0.452 ± 0.026	3.529PheAsp: 3.529 ± 0.066	3.478PheGlu: 3.478 ± 0.06	2.54PhePhe: 2.54 ± 0.066	3.618PheGly: 3.618 ± 0.076	0.712PheHis: 0.712 ± 0.032	3.895PheIle: 3.895 ± 0.075	4.339PheLys: 4.339 ± 0.082	4.505PheLeu: 4.505 ± 0.093	1.045PheMet: 1.045 ± 0.034	3.874PheAsn: 3.874 ± 0.076	1.597PhePro: 1.597 ± 0.044	1.461PheGln: 1.461 ± 0.037	1.465PheArg: 1.465 ± 0.045	3.866PheSer: 3.866 ± 0.072	3.299PheThr: 3.299 ± 0.068	3.031PheVal: 3.031 ± 0.058	0.525PheTrp: 0.525 ± 0.025	2.134PheTyr: 2.134 ± 0.052	0.0PheXaa: 0.0 ± 0.0
Gly	3.847GlyAla: 3.847 ± 0.092	0.638GlyCys: 0.638 ± 0.034	3.576GlyAsp: 3.576 ± 0.084	3.327GlyGlu: 3.327 ± 0.07	3.686GlyPhe: 3.686 ± 0.07	4.347GlyGly: 4.347 ± 0.105	1.157GlyHis: 1.157 ± 0.04	4.892GlyIle: 4.892 ± 0.091	4.414GlyLys: 4.414 ± 0.079	5.797GlyLeu: 5.797 ± 0.083	1.388GlyMet: 1.388 ± 0.048	3.685GlyAsn: 3.685 ± 0.083	1.276GlyPro: 1.276 ± 0.039	2.117GlyGln: 2.117 ± 0.052	1.949GlyArg: 1.949 ± 0.049	3.743GlySer: 3.743 ± 0.079	4.145GlyThr: 4.145 ± 0.101	4.252GlyVal: 4.252 ± 0.075	0.698GlyTrp: 0.698 ± 0.031	2.67GlyTyr: 2.67 ± 0.06	0.0GlyXaa: 0.0 ± 0.0
His	0.945HisAla: 0.945 ± 0.032	0.176HisCys: 0.176 ± 0.014	0.88HisAsp: 0.88 ± 0.033	0.849HisGlu: 0.849 ± 0.03	1.167HisPhe: 1.167 ± 0.043	0.97HisGly: 0.97 ± 0.035	0.459HisHis: 0.459 ± 0.026	1.412HisIle: 1.412 ± 0.041	1.208HisLys: 1.208 ± 0.038	1.812HisLeu: 1.812 ± 0.05	0.3HisMet: 0.3 ± 0.02	1.076HisAsn: 1.076 ± 0.033	0.852HisPro: 0.852 ± 0.036	0.722HisGln: 0.722 ± 0.03	0.57HisArg: 0.57 ± 0.024	0.926HisSer: 0.926 ± 0.035	0.933HisThr: 0.933 ± 0.032	1.011HisVal: 1.011 ± 0.039	0.207HisTrp: 0.207 ± 0.014	0.862HisTyr: 0.862 ± 0.033	0.0HisXaa: 0.0 ± 0.0
Ile	5.486IleAla: 5.486 ± 0.093	0.6IleCys: 0.6 ± 0.029	5.169IleAsp: 5.169 ± 0.077	5.402IleGlu: 5.402 ± 0.081	3.401IlePhe: 3.401 ± 0.067	4.916IleGly: 4.916 ± 0.084	1.311IleHis: 1.311 ± 0.04	6.356IleIle: 6.356 ± 0.107	6.328IleLys: 6.328 ± 0.087	6.841IleLeu: 6.841 ± 0.112	1.328IleMet: 1.328 ± 0.043	5.302IleAsn: 5.302 ± 0.093	3.244IlePro: 3.244 ± 0.063	2.559IleGln: 2.559 ± 0.047	2.212IleArg: 2.212 ± 0.052	5.246IleSer: 5.246 ± 0.075	5.112IleThr: 5.112 ± 0.095	5.004IleVal: 5.004 ± 0.083	0.638IleTrp: 0.638 ± 0.025	2.814IleTyr: 2.814 ± 0.057	0.0IleXaa: 0.0 ± 0.0
Lys	5.271LysAla: 5.271 ± 0.097	0.357LysCys: 0.357 ± 0.023	4.927LysAsp: 4.927 ± 0.095	5.487LysGlu: 5.487 ± 0.095	2.751LysPhe: 2.751 ± 0.064	4.268LysGly: 4.268 ± 0.087	1.612LysHis: 1.612 ± 0.05	5.864LysIle: 5.864 ± 0.091	6.477LysLys: 6.477 ± 0.112	6.841LysLeu: 6.841 ± 0.096	1.862LysMet: 1.862 ± 0.043	5.229LysAsn: 5.229 ± 0.09	2.586LysPro: 2.586 ± 0.063	3.526LysGln: 3.526 ± 0.074	2.785LysArg: 2.785 ± 0.072	4.424LysSer: 4.424 ± 0.075	5.283LysThr: 5.283 ± 0.089	4.585LysVal: 4.585 ± 0.07	0.685LysTrp: 0.685 ± 0.032	2.999LysTyr: 2.999 ± 0.07	0.0LysXaa: 0.0 ± 0.0
Leu	5.556LeuAla: 5.556 ± 0.094	0.635LeuCys: 0.635 ± 0.028	5.693LeuAsp: 5.693 ± 0.088	6.108LeuGlu: 6.108 ± 0.095	4.901LeuPhe: 4.901 ± 0.091	5.676LeuGly: 5.676 ± 0.099	1.555LeuHis: 1.555 ± 0.047	7.064LeuIle: 7.064 ± 0.122	8.15LeuLys: 8.15 ± 0.115	8.413LeuLeu: 8.413 ± 0.13	1.954LeuMet: 1.954 ± 0.052	6.191LeuAsn: 6.191 ± 0.092	3.407LeuPro: 3.407 ± 0.058	3.293LeuGln: 3.293 ± 0.069	2.858LeuArg: 2.858 ± 0.051	6.43LeuSer: 6.43 ± 0.096	5.252LeuThr: 5.252 ± 0.092	5.57LeuVal: 5.57 ± 0.074	0.749LeuTrp: 0.749 ± 0.029	3.116LeuTyr: 3.116 ± 0.067	0.0LeuXaa: 0.0 ± 0.0
Met	1.369MetAla: 1.369 ± 0.041	0.126MetCys: 0.126 ± 0.012	1.059MetAsp: 1.059 ± 0.034	1.137MetGlu: 1.137 ± 0.041	0.816MetPhe: 0.816 ± 0.03	1.067MetGly: 1.067 ± 0.045	0.367MetHis: 0.367 ± 0.021	1.401MetIle: 1.401 ± 0.043	2.005MetLys: 2.005 ± 0.042	1.899MetLeu: 1.899 ± 0.05	0.508MetMet: 0.508 ± 0.028	1.103MetAsn: 1.103 ± 0.033	0.772MetPro: 0.772 ± 0.029	0.911MetGln: 0.911 ± 0.033	0.74MetArg: 0.74 ± 0.032	1.439MetSer: 1.439 ± 0.036	1.207MetThr: 1.207 ± 0.035	1.29MetVal: 1.29 ± 0.036	0.15MetTrp: 0.15 ± 0.013	0.708MetTyr: 0.708 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	4.064AsnAla: 4.064 ± 0.068	0.502AsnCys: 0.502 ± 0.028	3.714AsnAsp: 3.714 ± 0.077	3.394AsnGlu: 3.394 ± 0.062	3.165AsnPhe: 3.165 ± 0.081	4.193AsnGly: 4.193 ± 0.084	1.069AsnHis: 1.069 ± 0.042	5.186AsnIle: 5.186 ± 0.088	4.778AsnLys: 4.778 ± 0.089	5.764AsnLeu: 5.764 ± 0.094	1.277AsnMet: 1.277 ± 0.037	5.151AsnAsn: 5.151 ± 0.118	3.011AsnPro: 3.011 ± 0.075	2.858AsnGln: 2.858 ± 0.064	2.07AsnArg: 2.07 ± 0.046	4.216AsnSer: 4.216 ± 0.081	4.666AsnThr: 4.666 ± 0.09	3.746AsnVal: 3.746 ± 0.066	0.802AsnTrp: 0.802 ± 0.03	3.28AsnTyr: 3.28 ± 0.077	0.0AsnXaa: 0.0 ± 0.0
Pro	1.775ProAla: 1.775 ± 0.061	0.226ProCys: 0.226 ± 0.017	1.944ProAsp: 1.944 ± 0.055	2.858ProGlu: 2.858 ± 0.055	1.84ProPhe: 1.84 ± 0.048	1.684ProGly: 1.684 ± 0.053	0.553ProHis: 0.553 ± 0.027	2.721ProIle: 2.721 ± 0.06	2.67ProLys: 2.67 ± 0.059	2.913ProLeu: 2.913 ± 0.061	0.661ProMet: 0.661 ± 0.03	2.474ProAsn: 2.474 ± 0.054	0.739ProPro: 0.739 ± 0.036	1.091ProGln: 1.091 ± 0.042	0.853ProArg: 0.853 ± 0.034	2.057ProSer: 2.057 ± 0.049	2.14ProThr: 2.14 ± 0.057	2.122ProVal: 2.122 ± 0.054	0.272ProTrp: 0.272 ± 0.019	1.365ProTyr: 1.365 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	2.226GlnAla: 2.226 ± 0.052	0.186GlnCys: 0.186 ± 0.015	2.119GlnAsp: 2.119 ± 0.054	2.265GlnGlu: 2.265 ± 0.047	2.109GlnPhe: 2.109 ± 0.05	1.766GlnGly: 1.766 ± 0.051	0.779GlnHis: 0.779 ± 0.031	2.828GlnIle: 2.828 ± 0.06	2.643GlnLys: 2.643 ± 0.056	3.989GlnLeu: 3.989 ± 0.068	0.78GlnMet: 0.78 ± 0.036	2.294GlnAsn: 2.294 ± 0.054	1.29GlnPro: 1.29 ± 0.045	1.731GlnGln: 1.731 ± 0.05	1.245GlnArg: 1.245 ± 0.04	2.118GlnSer: 2.118 ± 0.051	2.214GlnThr: 2.214 ± 0.053	2.217GlnVal: 2.217 ± 0.052	0.366GlnTrp: 0.366 ± 0.019	1.467GlnTyr: 1.467 ± 0.041	0.0GlnXaa: 0.0 ± 0.0
Arg	2.0ArgAla: 2.0 ± 0.042	0.171ArgCys: 0.171 ± 0.016	1.724ArgAsp: 1.724 ± 0.046	1.868ArgGlu: 1.868 ± 0.049	1.777ArgPhe: 1.777 ± 0.049	1.804ArgGly: 1.804 ± 0.047	0.557ArgHis: 0.557 ± 0.024	2.449ArgIle: 2.449 ± 0.05	2.299ArgLys: 2.299 ± 0.051	3.036ArgLeu: 3.036 ± 0.058	0.711ArgMet: 0.711 ± 0.025	1.775ArgAsn: 1.775 ± 0.045	1.009ArgPro: 1.009 ± 0.042	1.233ArgGln: 1.233 ± 0.039	1.222ArgArg: 1.222 ± 0.042	1.638ArgSer: 1.638 ± 0.043	1.749ArgThr: 1.749 ± 0.053	1.982ArgVal: 1.982 ± 0.043	0.347ArgTrp: 0.347 ± 0.02	1.407ArgTyr: 1.407 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	3.626SerAla: 3.626 ± 0.074	0.618SerCys: 0.618 ± 0.032	3.569SerAsp: 3.569 ± 0.072	3.68SerGlu: 3.68 ± 0.064	3.613SerPhe: 3.613 ± 0.067	4.454SerGly: 4.454 ± 0.089	1.022SerHis: 1.022 ± 0.038	5.149SerIle: 5.149 ± 0.086	4.961SerLys: 4.961 ± 0.082	5.637SerLeu: 5.637 ± 0.088	1.127SerMet: 1.127 ± 0.036	4.327SerAsn: 4.327 ± 0.084	1.941SerPro: 1.941 ± 0.045	2.266SerGln: 2.266 ± 0.047	1.825SerArg: 1.825 ± 0.045	4.032SerSer: 4.032 ± 0.089	3.922SerThr: 3.922 ± 0.093	3.939SerVal: 3.939 ± 0.063	0.599SerTrp: 0.599 ± 0.023	2.635SerTyr: 2.635 ± 0.062	0.0SerXaa: 0.0 ± 0.0
Thr	3.676ThrAla: 3.676 ± 0.073	0.422ThrCys: 0.422 ± 0.025	3.57ThrAsp: 3.57 ± 0.074	3.694ThrGlu: 3.694 ± 0.065	3.41ThrPhe: 3.41 ± 0.068	3.968ThrGly: 3.968 ± 0.094	1.017ThrHis: 1.017 ± 0.041	5.838ThrIle: 5.838 ± 0.089	4.512ThrLys: 4.512 ± 0.068	6.015ThrLeu: 6.015 ± 0.087	1.002ThrMet: 1.002 ± 0.037	4.133ThrAsn: 4.133 ± 0.088	2.508ThrPro: 2.508 ± 0.067	2.144ThrGln: 2.144 ± 0.054	1.579ThrArg: 1.579 ± 0.046	4.225ThrSer: 4.225 ± 0.089	4.372ThrThr: 4.372 ± 0.103	4.103ThrVal: 4.103 ± 0.089	0.648ThrTrp: 0.648 ± 0.029	2.551ThrTyr: 2.551 ± 0.063	0.0ThrXaa: 0.0 ± 0.0
Val	4.106ValAla: 4.106 ± 0.073	0.529ValCys: 0.529 ± 0.028	3.764ValAsp: 3.764 ± 0.076	3.838ValGlu: 3.838 ± 0.073	3.706ValPhe: 3.706 ± 0.063	3.85ValGly: 3.85 ± 0.077	0.887ValHis: 0.887 ± 0.036	4.924ValIle: 4.924 ± 0.09	4.465ValLys: 4.465 ± 0.075	6.134ValLeu: 6.134 ± 0.082	1.292ValMet: 1.292 ± 0.039	3.94ValAsn: 3.94 ± 0.073	2.019ValPro: 2.019 ± 0.053	1.71ValGln: 1.71 ± 0.043	1.791ValArg: 1.791 ± 0.048	4.403ValSer: 4.403 ± 0.072	4.128ValThr: 4.128 ± 0.082	4.299ValVal: 4.299 ± 0.084	0.561ValTrp: 0.561 ± 0.025	2.432ValTyr: 2.432 ± 0.053	0.0ValXaa: 0.0 ± 0.0
Trp	0.508TrpAla: 0.508 ± 0.026	0.088TrpCys: 0.088 ± 0.01	0.606TrpAsp: 0.606 ± 0.027	0.615TrpGlu: 0.615 ± 0.031	0.552TrpPhe: 0.552 ± 0.027	0.506TrpGly: 0.506 ± 0.027	0.192TrpHis: 0.192 ± 0.014	0.681TrpIle: 0.681 ± 0.024	0.696TrpLys: 0.696 ± 0.031	0.956TrpLeu: 0.956 ± 0.035	0.288TrpMet: 0.288 ± 0.019	0.673TrpAsn: 0.673 ± 0.031	0.194TrpPro: 0.194 ± 0.016	0.388TrpGln: 0.388 ± 0.02	0.347TrpArg: 0.347 ± 0.022	0.681TrpSer: 0.681 ± 0.029	0.628TrpThr: 0.628 ± 0.03	0.556TrpVal: 0.556 ± 0.029	0.129TrpTrp: 0.129 ± 0.014	0.421TrpTyr: 0.421 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.378TyrAla: 2.378 ± 0.049	0.314TyrCys: 0.314 ± 0.018	2.419TyrAsp: 2.419 ± 0.052	1.898TyrGlu: 1.898 ± 0.05	2.43TyrPhe: 2.43 ± 0.058	2.59TyrGly: 2.59 ± 0.049	0.792TyrHis: 0.792 ± 0.033	2.845TyrIle: 2.845 ± 0.054	3.266TyrLys: 3.266 ± 0.074	3.906TyrLeu: 3.906 ± 0.067	0.686TyrMet: 0.686 ± 0.028	3.121TyrAsn: 3.121 ± 0.075	1.345TyrPro: 1.345 ± 0.044	1.607TyrGln: 1.607 ± 0.05	1.472TyrArg: 1.472 ± 0.043	2.549TyrSer: 2.549 ± 0.06	2.521TyrThr: 2.521 ± 0.064	2.279TyrVal: 2.279 ± 0.046	0.463TyrTrp: 0.463 ± 0.025	1.835TyrTyr: 1.835 ± 0.054	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2642 proteins (899899 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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